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https://www.readbyqxmd.com/read/29329787/outcomes-of-multisegmental-transforaminal-enlarged-decompression-plus-posterior-pedicle-screw-fixation-for-multilevel-lumbar-spinal-canal-stenosis-associated-with-lumbar-instability
#1
Chao Sun, Wei Ji Tian, Hui Xin Liu, Ping Guo Guan
PURPOSE: The aim of this study was to evaluate the clinical and radiologic results of multisegmental transforaminal enlarged decompression (TED) plus posterior pedicle screw fixation in the treatment of multilevel lumbar spinal canal stenosis (LSCS) with lumbar instability (MLSCSI). METHODS: 113 patients with MLSCSI underwent surgery were recruited in this study. All patients were suffering from symptoms typical of degenerative LSCS and treated with either TED plus fusion (TEDF group) or conventional laminectomy plus fusion (CLF group)...
January 9, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29329586/il-33-st2-signaling-contributes-to-radicular-pain-by-modulating-mapk-and-nf-%C3%AE%C2%BAb-activation-and-inflammatory-mediator-expression-in-the-spinal-cord-in-rat-models-of-noncompressive-lumber-disk-herniation
#2
Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou, Jian-Gang Luo
BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the nervous system. Thus, the purpose of this study is to investigate the expression of IL-33 and its receptor ST2 in the dorsal spinal cord and to elucidate whether the inhibition of spinal IL-33 expression significantly attenuates pain-related behaviors in rat models of noncompressive lumbar disc herniation...
January 12, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29325949/the-comparison-of-med-and-peld-in-the-treatment-of-adolescent-lumbar-disc-herniation-a-five-year-retrospective-follow-up
#3
Haiyin Li, Changqing Li, Changqing Jiang, Xuesong Mu, Weiren Lan, Yue Zhou
No abstract text is available yet for this article.
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29322966/the-influence-of-adjunctive-caudal-epidural-steroid-injection-on-the-therapeutic-effect-of-transforaminal-epidural-steroid-injection
#4
Atilla Kircelli, Tufan Cansever, Cem Yılmaz
BACKGROUND: Epidural steroid injection is widely used to treat the short and long-term symptoms of low back and radicular pain. To the best of our knowledge, the influence of transforaminal epidural steroid injection (TFSI) combined with caudal epidural steroid injection (CESI) on pain intensity, patient satisfaction, and quality of life in lumbar radiculopathy has not been examined. AIM: To evaluate the short and long-term efficacy of TFSI, and TFSI combined with CESI (TFSI + CESI) in patients with lumbar radiculopathy...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29322911/comparison-of-lumbar-pedicular-dynamic-stabilisation-systems-versus-fusion-for-the-treatment-of-lumbar-degenerative-disc-disease-a-meta-analysis
#5
Y-J Huang, S-J Zhao, Q Zhang, L-M Nong, N-W Xu
This study aimed to systematically compare the safety, effectiveness and radiological changes after lumbar pedicular dynamic stabilisation systems and fusion to treat lumbar degenerative disc disease . All studies that were performed to compare various lumbar pedicular dynamic stabilisation systems with any lumbar fusion to treat lumbar degenerative disc disease and were published until April 30, 2015 were acquired through a comprehensive search in various databases. A meta-analysis was performed after the methodological qualities of trials were assessed and after data were extracted...
March 2017: Acta Orthopaedica Belgica
https://www.readbyqxmd.com/read/29322267/association-of-decision-making-in-spinal-surgery-with-specialty-and-emotional-involvement-the-indications-in-spinal-surgery-indiana-survey
#6
Nico Sollmann, Carmen Morandell, Lucia Albers, Michael Behr, Alexander Preuss, Andreas Dinkel, Bernhard Meyer, Sandro M Krieg
BACKGROUND: Although recent trials provided level I evidence for the most common degenerative lumbar spinal disorders, treatment still varies widely. Thus, the Indications in Spinal Surgery (INDIANA) survey explores whether decision-making is influenced by specialty or personal emotional involvement of the treating specialist. METHOD: Nationwide, neurosurgeons and orthopedic surgeons specialized in spine surgery were asked to answer an Internet-based questionnaire with typical clinical patient cases of lumbar disc herniation (DH), lumbar spinal stenosis (SS), and lumbar degenerative spondylolisthesis (SL)...
January 10, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29321948/performance-of-an-annular-closure-device-in-a-real-world-heterogeneous-at-risk-lumbar-discectomy-population
#7
Adisa Kuršumović, Stefan Rath
Study design/setting Retrospective analysis of single-center registry outcomes data. Objective Assess the utility of an annular closure device (ACD) as an adjunct to limited discectomy for lumbar disc herniation (LDH). Background Recurrent lumbar disc herniation (rLDH) following limited discectomy persists at clinically significant rates, especially in large annular defect (at least 6 mm width) patients. While the etiology of reherniation is often multifactorial, inadequate annular occlusion remains one of the foremost considerations...
November 6, 2017: Curēus
https://www.readbyqxmd.com/read/29321344/a-genetic-variant-in-col11a1-is-functionally-associated-with-lumbar-disc-herniation-in-chinese-population
#8
Wenjun Liu, Guisen Sun, Longsheng Guo, Lulu Wang, Weiqiang Fan, Minglei Lang, Dan Chen, Xinhao Yi
This study aimed to explore whether the genetic variant of COL11A1 is functionally associated with the development of lumbar disc herniation (LDH) in Chinese population. SNP rs1676486 of COL11A1 was genotyped in 647 patients and 532 healthy controls. The differences of genotype and allele distributions between LDH patients and healthy controls were evaluated using the χ² test. One-way ANOVA test was used to compare the relationship between genotypes and clinical features including tissue expression of COL11A1 and the degree of disc degeneration...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29316495/vdr-and-gc-gene-polymorphisms-modulate-the-risk-of-lumbar-disc-degeneration-in-iran
#9
Sohail Mashayekhi, Alia Saberi, Zivar Salehi, Gelareh Biazar, Roghayeh Mehrdel
OBJECTIVE: Lumbar disc degeneration (LDD) occurs commonly in humans. Vitamin D metabolic and signaling pathway plays a significant role in intervertebral disc degeneration. The aim of this study was to evaluate the influence of the genetic polymorphism in the two key genes of 1,25-(OH)2-D3 pathway, VDR (vitamin D receptor) and GC (group-specific component), in LDD development. PATIENTS AND METHODS: Two single-nucleotide polymorphisms, VDR rs2228570 (FokI) and GC rs7041, were genotyped in 180 patients with LDD and 230 healthy individuals...
December 29, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29315127/tidemark-avulsions-are-a-predominant-form-of-endplate-irregularity
#10
Britta Berg-Johansen, Deeptee Jain, Ellen C Liebenberg, Aaron J Fields, Thomas M Link, Conor W O'Neill, Jeffrey C Lotz
STUDY DESIGN: Descriptive histologic and MRI study of human cadaveric spines. OBJECTIVE: To identify and characterize common endplate pathologies to form a histologic foundation for an etiology-based classification system. SUMMARY OF BACKGROUND DATA: Irregularities at the spinal disc-vertebra interface are associated with back pain and intervertebral disc herniation injuries. However, there is currently a lack of consensus regarding terminology for classification...
January 8, 2018: Spine
https://www.readbyqxmd.com/read/29315122/should-patients-with-recurrent-lumbar-disc-herniations-be-fused
#11
Michael J Elsenbeck, Stephen Fernicola, Scott C Wagner
No abstract text is available yet for this article.
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29312845/transforaminal-percutaneous-endoscopic-discectomy-using-transforaminal-endoscopic-spine-system-technique-pitfalls-that-a-beginner-should-avoid
#12
REVIEW
Stylianos Kapetanakis, Grigorios Gkasdaris, Antonios G Angoules, Panagiotis Givissis
Transforaminal Percutaneous Endoscopic Discectomy (TPED) is a minimally invasive technique mainly used for the treatment of lumbar disc herniation from a lateral approach. Performed under local anesthesia, TPED has been proven to be a safe and effective technique which has been also associated with shorter rehabilitation period, reduced blood loss, trauma, and scar tissue compared to conventional procedures. However, the procedure should be performed by a spine surgeon experienced in the specific technique and capable of recognizing or avoiding various challenging conditions...
December 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29310920/total-hip-arthroplasty-patients-with-fixed-spinopelvic-alignment-are-at-higher-risk-of-hip-dislocation
#13
Christina I Esposito, Kaitlin M Carroll, Peter K Sculco, Douglas E Padgett, Seth A Jerabek, David J Mayman
BACKGROUND: Sitting radiographs have been used as a pre-operative tool to plan patient-specific total hip arthroplasty (THA) component position that would improve hip stability. Previous work has demonstrated that spinal mobility may impact functional acetabular position when seated. We sought to determine whether patients who dislocate following THA have different sitting spinopelvic alignment or acetabular component orientation compared to patients who did not dislocate. METHODS: A consecutive series of 1000 patients underwent post-operative low-dose biplanar spine-to-ankle lateral radiographs in standing and sitting positions 1 year following THA...
December 13, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29307048/biomechanical-analysis-of-a-new-lumbar-interspinous-device-with-optimized-topology
#14
Chen-Sheng Chen, Shih-Liang Shih
Interspinous spacers used stand-alone preserve joint movement but provide little protection for diseased segments of the spine. Used as adjuncts with fusion, interspinous spacers offer rigid stability but may accelerate degeneration on adjacent levels. Our new device is intended to balance the stability and preserves motion provided by the implant. A new interspinous spacer was devised according to the results of topology optimization studies. Four finite element (FE) spine models were created that consisted of an intact spine without an implant, implantation of the novel, the device for intervertebral assisted motion (DIAM system), and the Dynesys system...
January 6, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29306376/sonography-guided-lumbar-nerve-and-facet-blocks-the-first-report-of-clinical-outcome-from-iran
#15
H Sadeghian, R Motiei-Langroudi
INTRODUCTION: Nerve root block (NRB) and facet block (FB) are viable options for pain arising from facet and lumbar disc herniation (LDH) not responding to conservative therapy but still not suitable for surgery. Classically, they are performed under fluoroscopy and computed tomography (CT) guidance, which have the disadvantages of radiation exposure and limited accessibility. The aim of this study was to assess the effectiveness of US guided FB and NRB in patients suffering from facet arthropathy and LDH...
February 2018: Radiography
https://www.readbyqxmd.com/read/29304802/evaluation-of-the-influence-of-kyphosis-and-scoliosis-on-intervertebral-disc-extrusion-in-french-bulldogs
#16
Maria Claudia C M Inglez de Souza, Richard Ryan, Gert Ter Haar, Rowena M A Packer, Holger A Volk, Steven De Decker
BACKGROUND: Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and intervertebral disc degeneration. It is however unknown if an abnormal spinal curvature also predisposes dogs to develop clinically relevant intervertebral disc herniations. The aim of this study was to evaluate if the occurrence of thoracic vertebral malformations, kyphosis or scoliosis would be associated with a higher prevalence of cervical or thoracolumbar intervertebral disc extrusion in French bulldogs...
January 5, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29303471/comparison-of-percutaneous-endoscopic-transforaminal-discectomy-microendoscopic-discectomy-and-microdiscectomy-for-symptomatic-lumbar-disc-herniation-minimum-2-year-follow-up-results
#17
Xinyu Liu, Suomao Yuan, Yonghao Tian, Lianlei Wang, Liangtai Gong, Yanping Zheng, Jianmin Li
OBJECTIVE This study aimed to evaluate the clinical outcomes of percutaneous endoscopic transforaminal discectomy (PETD), microendoscopic discectomy (MED), and microdiscectomy (MD) for treatment of symptomatic lumbar disc herniation (LDH). METHODS One hundred ninety-two patients with symptomatic LDH at L3-4 and L4-5 were included in this study. The mean (± SD) age of patients was 34.2 ± 2.6 years (range 18-62 years). The patients were divided into groups as follows: group A was treated with PETD and included 60 patients (31 men and 29 women) with a mean age of 36...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29303469/percutaneous-transforaminal-endoscopic-discectomy-compared-with-microendoscopic-discectomy-for-lumbar-disc-herniation-1-year-results-of-an-ongoing-randomized-controlled-trial
#18
Zihao Chen, Liangming Zhang, Jianwen Dong, Peigen Xie, Bin Liu, Qiyou Wang, Ruiqiang Chen, Feng Feng, Bu Yang, Tao Shu, Shangfu Li, Yang Yang, Lei He, Mao Pang, Limin Rong
OBJECTIVE A prospective randomized controlled study was conducted to clarify whether percutaneous transforaminal endoscopic discectomy (PTED) results in better clinical outcomes and less surgical trauma than microendoscopic discectomy (MED). METHODS In this single-center, open-label, randomized controlled trial, patients were included if they had persistent signs and symptoms of radiculopathy with corresponding imaging-confirmed lumbar disc herniation. Patients were randomly allocated to the PTED or the MED group by computer-generated randomization codes...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29301175/whole-spine-disc-degeneration-survey-according-to-the-ages-and-sex-using-pfirrmann-disc-degeneration-grades
#19
Chang Hyun Oh, Seung Hwan Yoon
OBJECTIVE: Pfirrmann disc grade is a useful scoring tool for evaluating disc degeneration, but normal values according to aging process has not been elucidated. This study was conducted to identify the prevalence and pattern of whole spine disc degeneration according to ages and gender differences. METHODS: Total 653 patients (336 male and 317 female patients, 48.1±58.7 years old) who took whole spine magnetic resonance images were enrolled in this study. There were 19 cases in their 2nd decades and 74 cases in 3rd decades, 141 cases in 4th decades, 129 cases in 5th decades, 139 cases in 6th decades, and 93 cases in 7th decades, 58 cases in over 8th decades...
December 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29299677/compression-of-a-giant-pseudomeningocele-causing-transient-anoxic-seizures-a-case-report
#20
Alhafidz Hamdan, A Saxena, G Rao, M Ivanov
Transient anoxic seizure upon application of pressure on a giant pseudomeningocele has never been reported in the literature; such abrupt changes in intracranial pressure due to large volume of cerebrospinal fluid (CSF) translocation, if left untreated may lead to permanent cerebral hypoxic injury and death. Here we describe a case of a 26-year-old woman who had undergone lumbar disc surgery in another unit few months ago and developed a large lump around her back. Any pressure on the lump resulted in headaches and at times episodes of seizures...
January 3, 2018: Acta Neurochirurgica
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