keyword
https://read.qxmd.com/read/38281307/cognitive-behavioral-therapy-for-insomnia-self-management-mobile-apps-a-review-of-efficacy-and-quality
#21
JOURNAL ARTICLE
Anderson B Rowan, Anna T Magnante, Nicole Urh, Lynette Figueroa
Cognitive behavioral therapy for insomnia (CBT-I) is the recommended treatment for insomnia, yet multiple barriers limit utilization. Digital CBT-I may present a solution, though related reviews have focused on Internet-based delivery rather than app use. The high utilization of health apps and prevalence of sleep apps indicate the need to equip clinicians with app-specific research. Toward this end, we reviewed efficacy and quality data on self-management CBT-I smartphone apps, revealing efficacy research on eleven apps, five of which were publicly available...
January 28, 2024: Journal of Clinical Psychology in Medical Settings
https://read.qxmd.com/read/38252172/development-and-pre-pilot-testing-of-stamp%C3%A2-%C3%A2-cbt-an-mhealth-app-combining-pain-cognitive-behavioral-therapy-and-opioid-support-for-patients-with-advanced-cancer-and-pain
#22
RANDOMIZED CONTROLLED TRIAL
Desiree R Azizoddin, Sara M DeForge, Ashton Baltazar, Robert R Edwards, Matthew Allsop, James A Tulsky, Michael S Businelle, Kristin L Schreiber, Andrea C Enzinger
PURPOSE: We developed and piloted a mobile health app to deliver cognitive behavioral therapy for pain (pain-CBT), remote symptom monitoring, and pharmacologic support for patients with pain from advanced cancer. METHODS: Using an iterative process of patient review and feedback, we developed the STAMP + CBT app. The app delivers brief daily lessons from pain-CBT and pain psychoeducation, adapted for advanced cancer. Daily surveys assess physical symptoms, psychological symptoms, opioid utilization and relief...
January 22, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38236638/testing-an-evidence-based-self-help-program-for-infertility-related-distress-protocol-for-a-randomized-controlled-trial
#23
JOURNAL ARTICLE
Jennifer L Gordon, Megan M L Poulter, Ashley A Balsom, Tavis S Campbell
BACKGROUND: Infertility-the inability to achieve pregnancy despite ≥12 months of focused attempts to conceive-is experienced by 1 in 6 couples. Women typically carry a disproportionate share of the psychological burden associated with infertility, experiencing poor quality of life, and 30%-40% experiencing depressive mood or anxiety. Unfortunately, currently available psychological interventions targeting infertility-related distress are associated with modest effects. OBJECTIVE: Our team, in collaboration with patient advisors, has designed a self-help intervention for infertility-related distress involving 7 weekly 10-minute videos addressing the cognitive, behavioral, and interpersonal challenges associated with infertility, delivered through a mobile app...
January 18, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38236634/development-and-usability-testing-of-an-mhealth-tool-for-trauma-informed-prevention-of-substance-use-hiv-acquisition-and-risky-sexual-behaviors-among-adolescents-mixed-methods-study
#24
JOURNAL ARTICLE
Carla Kmett Danielson, Angela Moreland, Austin Hahn, Devin Banks, Kenneth J Ruggiero
BACKGROUND: Youth who experience traumatic events are at a substantially higher risk of engaging in substance use and sexual risk behaviors and problems (eg, HIV acquisition) than their non-trauma-exposed counterparts. Evidence-based substance use and risky sexual behavior prevention may reduce the risk of these outcomes. Trauma-focused mental health treatment provides a window of opportunity for the implementation of such preventive work with these youth. However, overburdened clinicians face challenges in adding prevention content while implementing evidence-based treatments...
January 18, 2024: JMIR Formative Research
https://read.qxmd.com/read/38216233/availability-of-internet-based-cognitive-behavioral-therapies-for-depression-a-systematic-review
#25
REVIEW
John F Buss, Joshua S Steinberg, Gregory Banks, Deena Horani, Lauren A Rutter, Akash R Wasil, Israel Ramirez, Lorenzo Lorenzo-Luaces
We examined the availability and components of internet-based cognitive-behavioral therapies (iCBTs) for depression tested in randomized-controlled trials (RCTs). The objectives of this literature review were to determine the extent to which research-validated iCBTs were available to the public, as well as to determine their therapeutic content. A literature review of RCTs for iCBTs was conducted on July 30, 2021. For each iCBT, interventions were rated by content and compared to commercially available smartphone apps...
January 2024: Behavior Therapy
https://read.qxmd.com/read/38214614/current-evidence-on-the-efficacy-of-mental-health-smartphone%C3%A2-apps-for-symptoms-of-depression-and-anxiety-a-meta-analysis-of-176-randomized-controlled-trials
#26
JOURNAL ARTICLE
Jake Linardon, John Torous, Joseph Firth, Pim Cuijpers, Mariel Messer, Matthew Fuller-Tyszkiewicz
The mental health care available for depression and anxiety has recently undergone a major technological revolution, with growing interest towards the potential of smartphone apps as a scalable tool to treat these conditions. Since the last comprehensive meta-analysis in 2019 established positive yet variable effects of apps on depressive and anxiety symptoms, more than 100 new randomized controlled trials (RCTs) have been carried out. We conducted an updated meta-analysis with the objectives of providing more precise estimates of effects, quantifying generalizability from this evidence base, and understanding whether major app and trial characteristics moderate effect sizes...
February 2024: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://read.qxmd.com/read/38201011/information-and-communication-technology-based-application-for-cognitive-behavioral-therapy-among-community-dwelling-older-adults-with-insomnia-development-and-validation-study
#27
JOURNAL ARTICLE
Yeonhee Lee, Inseong Kim, Seonheui Lee, Soyoung Yu
This study developed an information and communication technology-based mobile application to administer cognitive behavioral therapy to community-dwelling older adults with insomnia. First, the content of the application was determined through a systematic review and preference survey. Preference data on the perception, needs, and preference for non-face-to-face service content were collected from 15 July 2021 to 31 August 2021 from 100 community-dwelling older adults aged 65 years and older. In the design stage, the structure and function of the application were determined, and an interface was designed...
January 2, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38177830/developing-a-novel-mobile-application-for-cognitive-behavioral-therapy-for-insomnia-for-people-with-schizophrenia-integration-of-wearable-and-environmental-sleep-sensors
#28
JOURNAL ARTICLE
Jae Min Jeon, Junhua Ma, Paulyn Kwak, Bing Dang, Italo Buleje, Sonia Ancoli-Israel, Atul Malhotra, Ellen E Lee
BACKGROUND: People with serious mental illnesses (SMIs) have three-fold higher rates of comorbid insomnia than the general population, which has downstream effects on cognitive, mental, and physical health. Cognitive Behavioral Therapy for Insomnia (CBT-i) is a safe and effective first-line treatment for insomnia, though the therapy's effectiveness relies on completing nightly sleep diaries which can be challenging for some people with SMI and comorbid cognitive deficits. Supportive technologies such as mobile applications and sleep sensors may aid with completing sleep diaries...
January 4, 2024: Sleep & Breathing
https://read.qxmd.com/read/38142630/effectiveness-of-telerehabilitation-plus-virtual-reality-tele-rv-in-cognitive-e-social-functioning-a-randomized-clinical-study-on-parkinson-s-disease
#29
RANDOMIZED CONTROLLED TRIAL
Maria Grazia Maggio, Antonina Luca, Calogero Edoardo Cicero, Rocco Salvatore Calabrò, Filippo Drago, Mario Zappia, Alessandra Nicoletti
INTRODUCTION: Telemedicine could represent an emerging and innovative approach to support cognitive and behavioral rehabilitation reducing the overload of healthcare facilities, favoring home care therapy. The present study aimed to assess the potential efficacy of Tele-VR apps in enhancing cognitive performance and improving social skills in patients with Parkinson's disease (PD). METHODS: Thirty-four patients with PD were included in the study. Patients were assigned to one of the following treatment groups: Experimental Group 1 (EG1) underwent a Tele-VR program using two cognitive rehabilitation applications (app) on smartphones (Neuronation-Brain Training and Train your Brain); Experimental Group 2 (EG2) received a Tele-VR program through one cognitive rehabilitation app (Neuronation-Brain Training) and one socio-cognitive rehabilitation App (The Sims) on smartphones; Active Control Group (aCG) performed a conventional training using pencil and paper exercises (Not-VR)...
February 2024: Parkinsonism & related Disorders
https://read.qxmd.com/read/38142018/knockdown-of-bace1-by-a-multistage-brain-targeting-polyion-complex-improved-memory-and-learning-behaviors-in-app-ps1-transgenic-mouse-model
#30
JOURNAL ARTICLE
Tingting Jia, Hongbo Wang, Wenya Chi, Wenbo Zhou, Lingyi Guo, Yu Dai, Kangqing Bian, Zhiguo Sun, Xueying Ding, Yuan Yu
Cleavage of Amyloid precursor protein (APP) by the β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the rate-limiting step in the production of amyloid-β (Aβ) synaptotoxins. The siRNA-mediated silencing to attenuate the expression of BACE1 to ameliorate cognitive dysfunction in mice had been investigated. To improve therapeutic gene delivery to the central nervous system, cationic copolymer poly(ethylene glycol)-b-poly[N-(N'-{N''-[N'''-(2-aminoethyl)-2-aminoethyl]-2-aminoethyl}-2-aminoethyl)aspartamide]-cholesterol was synthesized, then RVG29 and Tet1 peptides were exploited as ligands to construct a dual-targeting brain gene delivery polyion complex (Tet1/RVG29-PIC)...
December 21, 2023: International Journal of Pharmaceutics
https://read.qxmd.com/read/38111016/amyloid-%C3%AE-specific-regulatory-t-cells-attenuate-alzheimer-s-disease-pathobiology-in-app-ps1-mice
#31
JOURNAL ARTICLE
Pravin Yeapuri, Jatin Machhi, Yaman Lu, Mai Mohamed Abdelmoaty, Rana Kadry, Milankumar Patel, Shaurav Bhattarai, Eugene Lu, Krista L Namminga, Katherine E Olson, Emma G Foster, R Lee Mosley, Howard E Gendelman
BACKGROUND: Regulatory T cells (Tregs) maintain immune tolerance. While Treg-mediated neuroprotective activities are now well-accepted, the lack of defined antigen specificity limits their therapeutic potential. This is notable for neurodegenerative diseases where cell access to injured brain regions is required for disease-specific therapeutic targeting and improved outcomes. To address this need, amyloid-beta (Aβ) antigen specificity was conferred to Treg responses by engineering the T cell receptor (TCR) specific for Aβ (TCRA β )...
December 18, 2023: Molecular Neurodegeneration
https://read.qxmd.com/read/38055315/self-guided-mental-health-apps-targeting-racial-and-ethnic-minority-groups-scoping-review
#32
REVIEW
Fiby Saad, Mia Eisenstadt, Shaun Liverpool, Courtney Carlsson, Isabella Vainieri
BACKGROUND: The use of mental health apps (MHAs) is increasing rapidly. However, little is known about the use of MHAs by racial and ethnic minority groups. OBJECTIVE: In this review, we aimed to examine the acceptability and effectiveness of MHAs among racial and ethnic minority groups, describe the purposes of using MHAs, identify the barriers to MHA use in racial and ethnic minority groups, and identify the gaps in the literature. METHODS: A systematic search was conducted on August 25, 2023, using Web of Science, Embase, PsycINFO, PsycArticles, PsycExtra, and MEDLINE...
December 6, 2023: JMIR Mental Health
https://read.qxmd.com/read/38043266/attenuated-memory-impairment-and-neuroinflammation-in-alzheimer-s-disease-by-aucubin-via-the-inhibition-of-erk-fos-axis
#33
JOURNAL ARTICLE
Cuicui Wang, Xiaolin Cui, Zhenfang Dong, Yingchao Liu, Pengcheng Xia, Xueying Wang, Zhi Zhang, Shuyi Yu, Shuang Wu, Huan Liu, Shuai Zong, Zhiming Lu
Alzheimer's disease (AD) is a degenerative illness accompanied by cognitive and memory loss. In addition to the widely accepted, convincing amyloid cascade hypothesis, the activation of glial cells and neuroinflammation, especially the microglia-mediated neuroinflammation, has an essential role in the development and progression of AD. Therefore, the anti-inflammatory treatment is becoming a promising therapeutic strategy. Aucubin (Au) is a natural product derived from many plants with anti-inflammatory and antioxidant activities...
December 2, 2023: International Immunopharmacology
https://read.qxmd.com/read/38029300/use-and-engagement-with-low-intensity-cognitive-behavioral-therapy-techniques-employed-within-an-app-to-support-worry-management-analysis-of-log-data
#34
JOURNAL ARTICLE
Paul Farrand, Patrick Raue, Earlise Ward, Dean Repper, Patricia Areán
BACKGROUND: Low-Intensity Cognitive Behavioral Therapy (CBT) self-help has been implemented into mental health service delivery to manage excessive worry associated with Generalized Anxiety Disorder (GAD) and support emotional wellbeing. However, being predominantly available within a written format presents barriers to access limiting scalability. A solution could be to incorporate low-intensity CBT techniques derived from an evidence-based protocol within a mental health wellbeing app for worry management supported through an algorithmically driven conversational agent...
November 28, 2023: JMIR MHealth and UHealth
https://read.qxmd.com/read/38027836/promoting-couples-resilience-to-relationship-obsessive-compulsive-disorder-rocd-symptoms-using-a-cbt-based-mobile-application-a-randomized-controlled-trial
#35
JOURNAL ARTICLE
Milana Gorelik, Ohad Szepsenwol, Guy Doron
Relationship Obsessive Compulsive Disorder (ROCD) is a disabling form of obsessive-compulsive disorder (OCD) centering on interpersonal relationships. Previous findings suggest ROCD symptoms are particularly detrimental to romantic relationships. In this randomized controlled trial (RCT), we assessed influence a CBT-based mobile application used by both partners on resilience to ROCD symptoms, cognitions, and relationship dissatisfaction. The app consists of brief, daily exercises targeting OCD symptoms, related cognitions and attachment insecurities...
November 2023: Heliyon
https://read.qxmd.com/read/38026413/interventions-to-reduce-stress-and-prevent-burnout-in-healthcare-professionals-supported-by-digital-applications-a-scoping-review
#36
REVIEW
Daniela Adam, Julia Berschick, Julia K Schiele, Martin Bogdanski, Marleen Schröter, Melanie Steinmetz, Anna K Koch, Jalid Sehouli, Sylvia Reschke, Wiebke Stritter, Christian S Kessler, Georg Seifert
AIM: Healthcare professionals are at increased risk of burnout, primarily due to workplace-related stressors. The COVID-19 pandemic has further increased this risk. Different interventions exist with varying degrees of effectiveness; little is reported on the content and implementation of such programs. This review fills this gap, with attention to recent programs using digital components. METHODS: PubMed, Embase, PsycInfo, and Google Scholar were searched between January 24th and 28th, 2022, limited to the last 5 years (≥2017)...
2023: Frontiers in Public Health
https://read.qxmd.com/read/38015607/treatment-responsivity-in-adolescents-with-disruptive-behavior-problems-co-creation-of-a-virtual-reality-based-add-on-intervention
#37
JOURNAL ARTICLE
Renée E Klein Schaarsberg, Amber Z Ribberink, Babette Osinga, Levi van Dam, Ramón J L Lindauer, Arne Popma
BACKGROUND: We developed Street Temptations (ST) as an add-on intervention to increase the treatment responsivity of adolescents with disruptive behavior problems. ST's primary aim is to improve adolescents' mentalizing abilities in order to help them engage in and benefit from psychotherapy. Additionally, virtual reality (VR) is used to work in a more visual, less verbal, fashion. OBJECTIVE: By recapping the lessons learned while developing ST so far, we aim to design the following study on ST...
November 28, 2023: JMIR Formative Research
https://read.qxmd.com/read/37991839/self-guided-digital-intervention-for-depression-in-adolescents-feasibility-and-preliminary-efficacy-study
#38
JOURNAL ARTICLE
Ian Miller, Emily Peake, Gabriel Strauss, Elise Vierra, Xin Koepsell, Brandon Shalchi, Aarthi Padmanabhan, Jessica Lake
BACKGROUND: Depression in adolescents is a large and growing problem; however, access to effective mental health care continues to be a challenge. Digitally based interventions may serve to bridge this access gap for adolescents in need of care. Digital interventions that deliver components of cognitive behavioral therapy (CBT) have been shown to reduce symptoms of depression, and virtual reality (VR) may be a promising adjunctive component. However, research on these types of treatments in adolescents and young adults is limited...
November 22, 2023: JMIR Formative Research
https://read.qxmd.com/read/37976479/the-use-of-telemedicine-in-outpatient-pain-management-a-scoping-review
#39
JOURNAL ARTICLE
Michael Hill-Oliva, Kelvin K Ampen-Darko, Paul Shekane, Samantha Walsh, Samuel DeMaria, Jonathan Gal, Alopi Patel
BACKGROUND: Telemedicine is an increasingly important tool in outpatient pain management. Telemedicine can be implemented through various strategies and a multitude of approaches have been described in existing literature. OBJECTIVES: This scoping review aims to survey how telemedicine has been approached in published literature, providing insight for continued implementation. STUDY DESIGN: Scoping review. SETTING: Outpatient pain management...
November 2023: Pain Physician
https://read.qxmd.com/read/37971800/assessing-the-efficacy-and-safety-of-a-digital-therapeutic-for-symptoms-of-depression-in-adolescents-protocol-for-a-randomized-controlled-trial
#40
JOURNAL ARTICLE
Daniella J Furman, Shana A Hall, Claudia Avina, Vera N Kulikov, Jessica I Lake, Aarthi Padmanabhan
BACKGROUND: Depression is a serious, prevalent, recurrent, and undertreated disorder in adolescents. Low levels of treatment seeking and treatment adherence in this age group, combined with a growing national crisis in access to mental health care, have increased efforts to identify effective treatment alternatives for this demographic. Digital health interventions for mental illness can provide cost-effective, engaging, and accessible means of delivering psychotherapy to adolescents...
November 16, 2023: JMIR Research Protocols
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