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Cognitive behavioral therapy app

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https://www.readbyqxmd.com/read/28687533/mobile-health-technology-using-a-wearable-sensorband-for-female-college-students-with-problem-drinking-an-acceptability-and-feasibility-study
#1
Noelle Regina Leonard, Michelle Silverman, Dawa Phuti Sherpa, Madeline A Naegle, Hyorim Kim, Donna L Coffman, Marcy Ferdschneider
BACKGROUND: An increasing number of mobile app interventions have been developed for problem drinking among college students; however, few studies have examined the integration of a mobile app with continuous physiological monitoring and alerting of affective states related to drinking behaviors. OBJECTIVE: The aim of this paper was to evaluate the acceptability and feasibility of Mind the Moment (MtM), a theoretically based intervention for female college students with problem drinking that combines brief, in-person counseling with ecological momentary intervention (EMI) on a mobile app integrated with a wearable sensorband...
July 7, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28597477/effective-expression-of-drebrin-in-hippocampus-improves-cognitive-function-and-alleviates-lesions-of-alzheimer-s-disease-in-app-swe-ps1-%C3%AE-e9-mice
#2
Yan Liu, Yan-Feng Xu, Ling Zhang, Lan Huang, Pin Yu, Hua Zhu, Wei Deng, Chuan Qin
AIMS: Alzheimer's disease (AD), a progressive development dementia, is increasingly impacting patients' living conditions worldwide. Despite medical care and funding support, there are still no highly individualized drugs and practical strategies for clinical prevention and treatment. Developmentally regulated brain protein (abbreviated as Drebrin or Dbn, also known as Dbn1 in mouse) exists in neurons, especially in dendrites, and is an actin-binding protein that modulates synaptic morphology and long-term memory...
July 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28596145/supporting-homework-compliance-in-cognitive-behavioural-therapy-essential-features-of-mobile-apps
#3
Wei Tang, David Kreindler
Cognitive behavioral therapy (CBT) is one of the most effective psychotherapy modalities used to treat depression and anxiety disorders. Homework is an integral component of CBT, but homework compliance in CBT remains problematic in real-life practice. The popularization of the mobile phone with app capabilities (smartphone) presents a unique opportunity to enhance CBT homework compliance; however, there are no guidelines for designing mobile phone apps created for this purpose. Existing literature suggests 6 essential features of an optimal mobile app for maximizing CBT homework compliance: (1) therapy congruency, (2) fostering learning, (3) guiding therapy, (4) connection building, (5) emphasis on completion, and (6) population specificity...
June 8, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28593105/photobiomodulation-with-near-infrared-light-helmet-in-a-pilot-placebo-controlled-clinical-trial-in-dementia-patients-testing-memory-and-cognition
#4
Marvin H Berman, James P Halper, Trent W Nichols, H Jarrett, Alan Lundy, Jason H Huang
Alzheimer's disease (AD) is a common, chronic expensive debilitating neurodegenerative disease with no current treatments to prevent the physical deterioration of the brain and the consequent cognitive deficits. The current pathophysiology of Alzheimer's disease is the accumulation of neurofibrillary tangles (NFTs) of hyperphosphorylated tau protein and amyloid-beta (Aβ) plaques. Antibody therapy of Tau and Amyloid beta, vaccines and other methods to decrease Tau and or Amyloid have not been successful after considerable pharmaceutical and biotech efforts...
2017: Journal of neurology and neuroscience
https://www.readbyqxmd.com/read/28588005/delivering-cognitive-behavior-therapy-to-young-adults-with-symptoms-of-depression-and-anxiety-using-a-fully-automated-conversational-agent-woebot-a-randomized-controlled-trial
#5
Kathleen Kara Fitzpatrick, Alison Darcy, Molly Vierhile
BACKGROUND: Web-based cognitive-behavioral therapeutic (CBT) apps have demonstrated efficacy but are characterized by poor adherence. Conversational agents may offer a convenient, engaging way of getting support at any time. OBJECTIVE: The objective of the study was to determine the feasibility, acceptability, and preliminary efficacy of a fully automated conversational agent to deliver a self-help program for college students who self-identify as having symptoms of anxiety and depression...
June 6, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28570436/integration-of-mobile-health-technology-in-the-treatment-of-chronic-pain-a-critical-review
#6
Lalitha V Sundararaman, Robert R Edwards, Edgar L Ross, Robert N Jamison
This article provides a critical overview and best-evidence synthesis of the use of mobile health (mHealth) technology among persons with chronic pain and their health care providers and examines the future benefits and barriers of implementing mHealth technology in clinical care. We critically review articles about electronic pain diaries, pain assessment programs, text messaging, and smartphone pain apps for management of persons with pain. Also presented are findings on the utility of activity trackers and use of telehealth to deliver cognitive behavioral therapy...
July 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28541464/quality-and-usability-of-arthritic-pain-self-management-apps-for-older-adults-a-systematic-review
#7
Priyanka Bhattarai, Tro Newton-John, Jane L Phillips
Objective.:  To appraise the quality and usability of currently available pain applications that could be used by community-dwelling older adults to self-manage their arthritic pain. Methods. : A systematic review. Searches were conducted in App Store and Google Play to identify pain self-management apps relevant to arthritic pain management. English language pain management apps providing pain assessment and documentation function and pain management education were considered for inclusion...
May 25, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28499574/use-of-computer-and-mobile-technologies-in-the-treatment-of-depression
#8
REVIEW
Judith A Callan, Jesse Wright, Greg J Siegle, Robert H Howland, Britney B Kepler
Major depression (MDD) is a common and disabling disorder. Research has shown that most people with MDD receive either no treatment or inadequate treatment. Computer and mobile technologies may offer solutions for the delivery of therapies to untreated or inadequately treated individuals with MDD. The authors review currently available technologies and research aimed at relieving symptoms of MDD. These technologies include computer-assisted cognitive-behavior therapy (CCBT), web-based self-help, Internet self-help support groups, mobile psychotherapeutic interventions (i...
June 2017: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/28494802/reducing-depressive-symptomatology-with-a-smartphone-app-study-protocol-for-a-randomized-placebo-controlled-trial
#9
Cezar Giosan, Oana Cobeanu, Cristina Mogoaşe, Aurora Szentagotai, Vlad Mureşan, Rareș Boian
BACKGROUND: Depression has become one of the leading contributors to the global disease burden. Evidence-based treatments for depression are available, but access to them is still limited in some instances. As technology has become more integrated into mental health care, computerized cognitive behavioral therapy (CBT) protocols have become available and have been recently transposed to mobile environments (e.g., smartphones) in the form of "apps." Preliminary research on some depression apps has shown promising results in reducing subthreshold or mild to moderate depressive symptoms...
May 12, 2017: Trials
https://www.readbyqxmd.com/read/28413833/beneficial-effects-of-a-pyrroloquinolinequinone-containing-dietary-formulation-on-motor-deficiency-cognitive-decline-and-mitochondrial-dysfunction-in-a-mouse-model-of-alzheimer-s-disease
#10
Darrell Sawmiller, Song Li, Takashi Mori, Ahsan Habib, David Rongo, Vedad Delic, Patrick C Bradshaw, R Douglas Shytle, Cyndy Sanberg, Paula Bickford, Jun Tan
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is linked to oxidative stress, altered amyloid precursor protein (APP) proteolysis, tau hyperphosphorylation and the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles (NFT). A growing body of evidence suggests that mitochondrial dysfunction can be a key promoter of all of these pathologies and predicts that restoration of mitochondrial function might be a potential therapeutic strategy for AD. Therefore, in the present study, we tested the beneficial effect of a nutraceutical formulation Nutrastem II (Nutra II), containing NT020 (a mitochondrial restorative and antioxidant proprietary formulation) and pyrroloquinolinequinone (PQQ, a stimulator of mitochondria biogenesis) in 5XFAD transgenic mice...
April 2017: Heliyon
https://www.readbyqxmd.com/read/28400355/mobile-phone-delivered-cognitive-behavioral-therapy-for-insomnia-a-randomized-waitlist-controlled-trial
#11
Corine Hg Horsch, Jaap Lancee, Fiemke Griffioen-Both, Sandor Spruit, Siska Fitrianie, Mark A Neerincx, Robbert Jan Beun, Willem-Paul Brinkman
BACKGROUND: This study is one of the first randomized controlled trials investigating cognitive behavioral therapy for insomnia (CBT-I) delivered by a fully automated mobile phone app. Such an app can potentially increase the accessibility of insomnia treatment for the 10% of people who have insomnia. OBJECTIVE: The objective of our study was to investigate the efficacy of CBT-I delivered via the Sleepcare mobile phone app, compared with a waitlist control group, in a randomized controlled trial...
April 11, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28330719/nicotinamide-mononucleotide-inhibits-jnk-activation-to-reverse-alzheimer-disease
#12
Zhiwen Yao, Wenhao Yang, Zhiqiang Gao, Peng Jia
Amyloid-β (Aβ) oligomers have been accepted as major neurotoxic agents in the therapy of Alzheimer's disease (AD). It has been shown that the activity of nicotinamide adenine dinucleotide (NAD+) is related with the decline of Aβ toxicity in AD. Nicotinamide mononucleotide (NMN), the important precursor of NAD+, is produced during the reaction of nicotinamide phosphoribosyl transferase (Nampt). This study aimed to figure out the potential therapeutic effects of NMN and its underlying mechanisms in APPswe/PS1dE9 (AD-Tg) mice...
March 19, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28246073/mobile-technology-use-by-people-experiencing-multiple-sclerosis-fatigue-survey-methodology
#13
Kirsten Van Kessel, Duncan R Babbage, Nicholas Reay, Warren M Miner-Williams, Paula Kersten
BACKGROUND: Fatigue is one of the most commonly reported symptoms of multiple sclerosis (MS). It has a profound impact on all spheres of life, for people with MS and their relatives. It is one of the key precipitants of early retirement. Individual, group, and Internet cognitive behavioral therapy-based approaches to supporting people with MS to manage their fatigue have been shown to be effective. OBJECTIVE: The aim of this project was to (1) survey the types of mobile devices and level of Internet access people with MS use or would consider using for a health intervention and (2) characterize the levels of fatigue severity and their impact experienced by the people in our sample to provide an estimate of fatigue severity of people with MS in New Zealand...
February 28, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28110674/evolution-of-cognitive-behavioral-therapy-for-eating-disorders
#14
W Stewart Agras, Ellen E Fitzsimmons-Craft, Denise E Wilfley
The evolution of cognitive-behavioral therapy (CBT) for the treatment of bulimic disorders is described in this review. The impacts of successive attempts to enhance CBT such as the addition of exposure and response prevention; the development of enhanced CBT; and broadening the treatment from bulimia nervosa to binge eating disorder are considered. In addition to developing advanced forms of CBT, shortening treatment to guided self-help was the first step in broadening access to treatment. The use of technology such as computer-based therapy and more recently the Internet, promises further broadening of access to self-help and to therapist guided treatment...
January 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28031038/using-a-smartphone-app-to-reduce-cognitive-vulnerability-and-mild-depressive-symptoms-study-protocol-of-an-exploratory-randomized-controlled-trial
#15
Cezar Giosan, Cristina Mogoaşe, Oana Cobeanu, Aurora Szentágotai Tătar, Vlad Mureşan, Rareș Boian
BACKGROUND: Depression is a major challenge worldwide, with significant increasing personal, economic, and societal costs. Although empirically supported treatments have been developed, they are not always available for patients in routine clinical care. Therefore, we need effective and widely accessible strategies to prevent the onset of the very first depressive symptoms. Mental health apps could prove a valuable solution for this desideratum. Although preliminary research has indicated that such apps can be useful in treating depression, no study has attempted to test their utility in preventing depressive symptoms...
December 28, 2016: Trials
https://www.readbyqxmd.com/read/27964740/lw-afc-a-new-formula-derived-from-liuwei-dihuang-decoction-ameliorates-behavioral-and-pathological-deterioration-via-modulating-the-neuroendocrine-immune-system-in-prp-ha%C3%AE-ppswe-ps1-%C3%AE-e9-transgenic-mice
#16
Jian-Hui Wang, Xi Lei, Xiao-Rui Cheng, Xiao-Rui Zhang, Gang Liu, Jun-Ping Cheng, Yi-Ran Xu, Ju Zeng, Wen-Xia Zhou, Yong-Xiang Zhang
BACKGROUND: Accumulating evidence implicates the neuroendocrine immunomodulation (NIM) network in the physiopathological mechanism of Alzheimer's disease (AD). Notably, we previously revealed that the NIM network is dysregulated in the PrP-hAβPPswe/PS1(ΔE9) (APP/PS1) transgenic mouse model of AD. METHODS: After treatment with a novel Liuwei Dihuang formula (LW-AFC), mice were cognitively evaluated in behavioral experiments. Neuron loss, amyloid-β (Aβ) deposition, and Aβ level were analyzed using Nissl staining, immunofluorescence, and an AlphaLISA assay, respectively...
December 13, 2016: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/27852560/safety-acceptability-and-use-of-a-smartphone-app-blueice-for-young-people-who-self-harm-protocol-for-an-open-phase-i-trial
#17
Paul Stallard, Joanna Porter, Rebecca Grist
BACKGROUND: Up to 18% of adolescents will engage in an act of self-harm before young adulthood, with the majority of acts occurring in private. Mobile apps may offer a way of providing support for young people at times of distress to prevent self-harm. OBJECTIVE: This is a proof-of-concept study designed to explore the safety, acceptability, feasibility, and usability of a smartphone app, BlueIce, with young people who are self-harming. METHODS: In this phase I open trial we will evaluate BlueIce, a smartphone app developed and coproduced with young people with lived experience of self-harm...
November 16, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27833071/cognitive-behavior-therapy-for-anxious-and-depressed-youth-improving-homework-adherence-through-mobile-technology
#18
Pamela Wilansky, J Mikael Eklund, Tracy Milner, David Kreindler, Amy Cheung, Tim Kovacs, Shahin Shooshtari, Arlene Astell, Arto Ohinmaa, Joanna Henderson, John Strauss, Rosemary Sl Mills
BACKGROUND: Anxiety and mood disorders are the most common mental illnesses, peaking during adolescence and affecting approximately 25% of Canadians aged 14-17 years. If not successfully treated at this age, they often persist into adulthood, exerting a great social and economic toll. Given the long-term impact, finding ways to increase the success and cost-effectiveness of mental health care is a pressing need. Cognitive behavior therapy (CBT) is an evidence-based treatment for mood and anxiety disorders throughout the lifespan...
November 10, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27598869/preclinical-assessment-of-young-blood-plasma-for-alzheimer-disease
#19
Jinte Middeldorp, Benoit Lehallier, Saul A Villeda, Suzanne S M Miedema, Emily Evans, Eva Czirr, Hui Zhang, Jian Luo, Trisha Stan, Kira I Mosher, Eliezer Masliah, Tony Wyss-Coray
Importance: Alzheimer disease (AD) pathology starts long before clinical symptoms manifest, and there is no therapy to treat, delay, or prevent the disease. A shared blood circulation between 2 mice (aka parabiosis) or repeated injections of young blood plasma (plasma from 2- to 3-month-old mice) into old mice has revealed benefits of young plasma on synaptic function and behavior. However, to our knowledge, the potential benefit of young blood has not been tested in preclinical models of neurodegeneration or AD...
November 1, 2016: JAMA Neurology
https://www.readbyqxmd.com/read/27565118/an-internet-based-intervention-for-depression-in-primary-care-in-spain-a-randomized-controlled-trial
#20
Jesús Montero-Marín, Ricardo Araya, María C Pérez-Yus, Fermín Mayoral, Margalida Gili, Cristina Botella, Rosa Baños, Adoración Castro, Pablo Romero-Sanchiz, Yolanda López-Del-Hoyo, Raquel Nogueira-Arjona, Margarita Vives, Antoni Riera, Javier García-Campayo
BACKGROUND: Depression is the most prevalent cause of illness-induced disability worldwide. Face-to-face psychotherapeutic interventions for depression can be challenging, so there is a need for other alternatives that allow these interventions to be offered. One feasible alternative is Internet-based psychological interventions. This is the first randomized controlled trial (RCT) on the effectiveness of an Internet-based intervention on depression in primary health care in Spain. OBJECTIVE: Our aim was to compare the effectiveness of a low-intensity therapist-guided (LITG) Internet-based program and a completely self-guided (CSG) Internet-based program with improved treatment as usual (iTAU) care for depression...
August 26, 2016: Journal of Medical Internet Research
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