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https://read.qxmd.com/read/38446563/association-of-demographic-characteristics-and-laboratory-values-in-diabetic-foot-infections-leading-to-lower-extremity-amputation
#1
JOURNAL ARTICLE
Allen J Kempf, Ellianne M Nasser, Idorenyin F Udoeyo, Isana Fils-Aime
BACKGROUND: Lower-extremity amputations are a common complication of poorly controlled diabetes and contribute to significant morbidity and mortality in diabetic patients. We sought to determine whether objective data points obtained on presentation or hospital admission, including white blood cell (WBC) count, hemoglobin A1c (HbA1c), C-reactive protein (CRP), and descriptive patient demographics allow for the ability to predict optimal amputation levels and outcomes of lower-extremity amputation in the diabetic population...
2024: Journal of the American Podiatric Medical Association
https://read.qxmd.com/read/38219509/advanced-wound-healing-in-a-patient-with-transmetatarsal-amputation-caused-by-severe-diabetic-foot-infection-a-case-report
#2
V R Serrudo, R Saurral, R Pool, A Kruler, N Sanchez, L M Carrio
Introduction and importance: Diabetic foot accounts for 50% to 95 % of non-traumatic amputations. The healing process of a surgical wound resulting from amputation in the diabetic foot is complex, and it is difficult to achieve an optimal outcome, which should include obtaining a functional stump for the patient. Healing is mainly hindered by infection, vascular disease, and wound size. In turn, biofilm formation significantly delays the healing process, increasing morbidity and impairing the amputee's quality of life...
January 10, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38164900/single-center-outcomes-of-percutaneous-deep-vein-arterialization-in-patients-with-end-stage-peripheral-artery-disease
#3
JOURNAL ARTICLE
Krystina N Choinski, Ajit G Rao, Prakash Krishnan, Rami O Tadros, Raman Sharma, Peter L Faries
Background: Peripheral artery disease (PAD) can present as chronic limb threatening ischemia (CLTI) with ischemic pain and tissue loss. Progression of distal disease can lead to a "no option" or end-stage disease without traditional open or endovascular revascularization due to lack of pedal targets. Innovations in endovascular technology allow for the use of percutaneous deep vein arterialization (pDVA) to treat patients with CLTI. Purpose: We describe our experience and technique for treating four patients with end-stage PAD with pDVA...
January 2, 2024: Vascular and Endovascular Surgery
https://read.qxmd.com/read/38111147/healing-rates-and-outcomes-following-closed-transmetatarsal-amputations-a-systematic-review-and-random-effects-meta-analysis-of-proportions
#4
REVIEW
Tyler Coye, Elizabeth Ansert, Mehmet A Suludere, Jayer Chung, Gu Eon Kang, Lawrence A Lavery
Transmetatarsal amputation (TMA) is a common surgical procedure for addressing severe forefoot pathologies, such as peripheral vascular disease and diabetic foot infections. Variability in research methodologies and findings within the existing literature has hindered a comprehensive understanding of healing rates and complications following TMA. This meta-analysis and systematic review aims to consolidate available evidence, synthesising data from multiple studies to assess healing rates and complications associated with closed TMA procedures...
December 18, 2023: Wound Repair and Regeneration
https://read.qxmd.com/read/37861666/a-preliminary-look-at-the-macrovascular-system-for-transmetatarsal-amputation-success
#5
JOURNAL ARTICLE
Elizabeth Ansert, John Najjar, Robert J Snyder
OBJECTIVE: Transmetatarsal amputation (TMA) is a commonly used level of amputation that preserves most of the foot's function and independence. However, many TMAs fail, and patients go onto higher amputations. The primary endpoint of this study is to determine if source artery occlusions are correlated with TMA flap failure. METHODS: A total of 82 patients with TMAs were retrospectively reviewed for healing rates between 2009 and 2019 at a single center. Forty-five of the patients had an angiogram, which was analyzed for source artery and overall TMA failure...
November 1, 2023: Advances in Skin & Wound Care
https://read.qxmd.com/read/37838089/morbidity-and-mortality-of-the-transmetatarsal-amputation-a-comparative-nsqip-analysis
#6
JOURNAL ARTICLE
Russell Hill, Kavya Ajbani, Benita Jebackumar, Temitope Adebayo, Andrew J Meyr
The objective of this investigation was to compare the morbidity and mortality of the transmetatarsal amputation to other frequently performed surgical procedures utilizing a large US database. The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database was interrogated for the purposes of this investigation. We initially extracted data related to the Current Procedural Terminology (CPT) code 28805 (amputation, foot; transmetatarsal) and the variable labels "estimated probability of morbidity" and "estimated probability of mortality"...
October 12, 2023: Journal of Foot and Ankle Surgery
https://read.qxmd.com/read/37834881/the-opportunity-for-impactful-integration-of-vascular-and-podiatric-care
#7
JOURNAL ARTICLE
Young Kim, Kevin W Southerland
BACKGROUND: The importance of collaboration between vascular and podiatric surgeons has been well-established. High-level partnerships are integral to the development of multidisciplinary programs and wound care centers, ultimately resulting in improved patient outcomes. This vascular-podiatric integration is not universal, however, and podiatric surgery may not be aligned within a vascular surgery division at many institutions. As one such institution, we reviewed our single-center experience in order to identify opportunities for the impactful integration of vascular-podiatric patient care...
September 27, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37799837/superior-mesenteric-artery-mycotic-aneurysm-repaired-with-bifurcated-saphenous-vein-graft
#8
Nicholas Girardi, Richard Denney, Lacey LaGrone
A mycotic aneurysm of the superior mesenteric artery caused by Enterococcus faecalis was successfully treated with aneurysmectomy and reconstruction with a bifurcated saphenous vein graft. A 49-year-old man with a history of type 2 diabetes mellitus and a recent left transmetatarsal amputation for osteomyelitis presented to the emergency department with severe abdominal pain, an unexplained 30-lb weight loss, and wound dehiscence. Computed tomography angiography showed an aneurysm of the superior mesenteric artery and a splenic abscess...
September 2023: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/37661019/30-day-readmission-following-outpatient-transmetatarsal-amputation-in-the-geriatric-population-an-acs-nsqip-analysis
#9
JOURNAL ARTICLE
Dominick J Casciato, Karen Kirkham, Jacob Wynes
Whether secondary to deformity, traumatic injury, infection, neoplasm, or ischemic disease, the transmetatarsal amputation provides a functional means of limb preservation prior to major proximal amputation. With similar readmission rates following inpatient and outpatient surgery, prevention of an unnecessary admission among vulnerable patients, specifically geriatrics, proves beneficial. This investigation examines differences among geriatric patients admitted and not requiring readmission following outpatient transmetatarsal amputation...
September 1, 2023: Journal of Foot and Ankle Surgery
https://read.qxmd.com/read/37643450/use-of-the-allg%C3%A3-wer-donati-suture-technique-for-wound-closure-following-transmetatarsal-amputation
#10
JOURNAL ARTICLE
Zachery Weyandt, Thomas Poynter, Nicolas Laco, Jonathan Towarnicki, Stephanie Coleman
INTRODUCTION: The Allgöwer-Donati suture technique reportedly has lower incision perfusion impairment compared with other suture techniques. The authors of the present case series hypothesized that suture technique selection to achieve lower incision perfusion impairment may result in improved healing rates and decreased incidence of wound complications in partial foot amputations, specifically TMAs. OBJECTIVE: To evaluate the efficacy of TMA with skin closure completed using the Allgöwer-Donati suture technique...
August 2023: Wounds: a Compendium of Clinical Research and Practice
https://read.qxmd.com/read/37622404/success-of-transmetatarsal-amputation-for-limb-salvage-in-patients-with-peripheral-artery-disease
#11
JOURNAL ARTICLE
David H Truong, Anthony K Ngoo, Shirling Tsai, Anna K Yang, Dane K Wukich, Lawrence A Lavery
Limb salvage is a difficult path for patients to travel as there is no guarantee of the outcome, often the major factor is perfusion. For patients who underwent transmetatarsal amputation (TMA), success rate is crucial as the next option is most likely a major amputation. We performed a 10 years (2010-2020) retrospective review of patients that underwent a TMA and had an angiogram or computed tomography angiography (CTA) perioperatively at the Dallas VA Medical Center. Failure after TMA was defined as a patient requiring a proximal amputation within 1 year...
January 2024: International Wound Journal
https://read.qxmd.com/read/37524241/minor-and-major-amputation-rates-following-midfoot-charcot-reconstructive-surgery
#12
JOURNAL ARTICLE
Sara Mateen, Michael A Thomas, Asma Jappar, Andrew J Meyr, Noman A Siddiqui
Charcot neuroarthropathy (CNA) is a progressive disease that affects the bones and joints of the foot. To prevent collapse and loss of stability within the pedal architecture, CNA should be diagnosed and managed early. The objective of this retrospective study was to review patients who underwent midfoot CNA reconstructive surgery and evaluate subsequent rates of minor and major amputations. Secondary objectives include identifying patients that underwent midfoot CAN with and without a subtalar joint arthrodesis...
July 29, 2023: Journal of Foot and Ankle Surgery
https://read.qxmd.com/read/37463195/the-diabetic-foot-pain-depression-cycle
#13
JOURNAL ARTICLE
Brandon M Brooks, Chia-Ding Shih, Bradley M Brooks, Dyane E Tower, Tiffany T Tran, Janet E Simon, David G Armstrong
BACKGROUND: More than 86,000 Americans with type 2 diabetes mellitus (T2DM) undergo nontraumatic lower-extremity amputations annually. The opioid-prescribing practice of podiatric surgeons remains understudied. We hypothesized that patients with T2DM who undergo any forefoot amputation while using antidepressant medication will have reduced odds of using opioids beyond 7 days. METHODS: We completed a retrospective cohort study examining patients with T2DM who underwent forefoot amputation (toe, ray, transmetatarsal)...
2023: Journal of the American Podiatric Medical Association
https://read.qxmd.com/read/37435393/risk-factors-for-failure-after-surgery-in-patients-with-diabetic-foot-syndrome
#14
JOURNAL ARTICLE
Helen Anwander, David Vonwyl, Verena Hecht, Moritz Tannast, Christophe Kurze, Fabian Krause
BACKGROUND: In the present study, we aimed to identify risk factors for failure (defined as reoperation within 60 days) after debridement or amputation at the lower extremity in patients with diabetic foot syndrome and to develop a model using the significant risk factors to predict the success rate at different levels of amputation. METHODS: Between September 2012 and November 2016, we performed a prospective observational cohort study of 174 surgeries in 105 patients with diabetic foot syndrome...
July 2023: Foot & ankle orthopaedics
https://read.qxmd.com/read/37289940/the-use-of-flap-techniques-to-preserve-limb-length-in-patients-with-transmetatarsal-amputations
#15
JOURNAL ARTICLE
Romina Deldar, Adaah A Sayyed, Gina Cach, Christopher Choi, Firras Garada, Jayson N Atves, John S Steinberg, Kenneth L Fan, Christopher E Attinger, Karen K Evans
BACKGROUND: Chronic lower extremity (LE) wounds affect up to 13% of the United States population. Transmetatarsal amputation (TMA) is frequently performed in comorbid patients with chronic forefoot wounds. TMA allows limb salvage and preserves functional gait, without need for prosthesis. Traditionally, when tension-free primary closure is not possible, a higher-level amputation is performed. This is the first series to evaluate the outcomes following local and free flap coverage of TMA stumps in patients with chronic foot wounds...
June 7, 2023: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/37263414/comparing-patient-and-provider-priorities-around-amputation-level-outcomes-using-multiple-criteria-decision-analysis
#16
JOURNAL ARTICLE
Diana Poehler, Joseph Czerniecki, Daniel Norvell, Alison Henderson, James Dolan, Beth Devine
BACKGROUND: Patients with chronic limb threatening ischemia may require a transmetatarsal or a transtibial amputation (TMA or TTA). When making an amputation-level decision, these patients face a tradeoff - a TMA preserves more limb and may provide better mobility, but has a lower probability of primary wound healing and may therefore result in additional same or higher level amputation surgeries with an associated negative impact on function. Understanding differences in how patients and providers prioritize these tradeoffs and other outcomes may enhance shared-decision making...
May 30, 2023: Annals of Vascular Surgery
https://read.qxmd.com/read/37212776/assessment-of-the-risk-factors-determining-the-prognosis-of-major-and-minor-limb-amputations-in-patients-with-diabetic-foot-ulcers
#17
JOURNAL ARTICLE
Kürşat Tuğrul Okur, Fırat Ozan, Murat Kahraman, Muhammed Melez, Ömer Can Ünlü, İbrahim Altun
BACKGROUND: Diabetes mellitus (DM) is a major global health problem, and its incidence is growing. Depending on this increase, the number of diabetes-related complications will also rise. OBJECTIVES: This study aimed to determine the risk factors associated with major and minor amputations resulting from diabetes. MATERIAL AND METHODS: Patients diagnosed with diabetic foot complications (n = 371) and hospitalized between January 2019 and March 2020 were retrospectively evaluated using information obtained from the database of Diabetic Foot Wound Clinic...
May 22, 2023: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://read.qxmd.com/read/37029973/new-antioxidant-therapy-for-hard-to-heal-neuroischaemic-diabetic-foot-ulcers-with-deep-exposure
#18
JOURNAL ARTICLE
Elena Pérez-Zabala, Andima Basterretxea, Begoña Castro, Alfonso Aizpuru, Jose Antonio Arancon, Carla Moreno, Arrate Zubizarreta, Zohartze Larizgoitia, August Ysa, Marta Lobato, Ainara Larrazabal
OBJECTIVE: To evaluate the clinical efficacy of a new antioxidant therapy for the treatment of complex neuroischaemic diabetic foot ulcers (DFUs). METHOD: A prospective case series study has been conducted in patients with complex neuroischaemic DFUs after transmetatarsal amputation. DFUs were locally treated with an antioxidant dressing twice a week for the first two weeks, and then once a week until the end of the study or complete wound closure. Patients were followed-up for eight weeks and assessed weekly to analyse wound outcome...
April 2, 2023: Journal of Wound Care
https://read.qxmd.com/read/36988702/inframalleolar-thrice-distal-puncture-in-a-single-endovascular-treatment-session-for-successful-revascularization
#19
JOURNAL ARTICLE
Issei Ota, Tetsuya Nomura, Kenshi Ono, Yu Sakaue, Keisuke Shoji, Naotoshi Wada
BACKGROUND: Most patients with chronic limb-threatening ischemia (CLTI) have infrapopliteal arterial disease, which are often challenging to treat. In endovascular treatment (EVT) for these complex lesions, establishing retrograde access is an essential option not only for guidewire crossing but also for device delivery. However, no EVT case has yet been reported requiring inframalleolar thrice distal puncture in a single EVT session so far. CASE PRESENTATION: A 60-year-old CLTI patient with grade 3 Wound, Ischemia and foot Infection (WIfI) classification underwent EVT for occluded dorsal artery and posterior tibial artery...
March 29, 2023: CVIR Endovascular
https://read.qxmd.com/read/36943915/risk-factors-for-a-failed-transmetatarsal-amputation-in-patients-with-diabetes
#20
JOURNAL ARTICLE
Itay Ron, Cynthia Kyin, Bezalel Peskin, Nabil Ghrayeb, Doron Norman, Tal Ben-Kiki, Jacob Shapira
BACKGROUND: Transmetatarsal amputation (TMA) is a well-recognized limb-salvage procedure, often indicated for the treatment of diabetic foot infections. Currently, there is no widespread agreement in the literature with regard to the factors associated with failure of TMA. This study aimed to define risk factors for the failure of TMA, defined as below-the-knee or above-the-knee amputation, in patients with diabetes. METHODS: This retrospective cohort study included 341 patients who underwent primary TMA...
May 3, 2023: Journal of Bone and Joint Surgery. American Volume
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