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Multivessel coronary artery disease

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https://www.readbyqxmd.com/read/28514396/-long-term-results-of-different-approaches-to-revascularization-in-non-st-segment-elevation-acute-coronary-syndrome-and-multiple-coronary-atherosclerosis
#1
V I Ganyukov, R S Tarasov, Yu N Neverova, N A Kochergin, O L Barbarash, L S Barbarash
AIM: To assess the long-term results of different approaches to treating patients with non-ST-segment elevation acute coronary syndrome (NSTE ACS) and multivessel coronary artery disease (MVCAD). SUBJECTS AND METHODS: A total of 150 patients with NSTE ACS, in whom coronary angiography revealed MVCAD, were examined. The patients were divided into 3 groups according to the selected treatment policy: 1) percutaneous coronary intervention (PCI) (n=91 (60.6%)); 2) coronary artery bypass grafting (CABG) (n=40 (26...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28504219/one-year-clinical-results-of-the-italian-diffuse-multivessel-disease-absorb-prospective-registry-it-disappears
#2
Luca Testa, Marco De Carlo, Alessandro Petrolini, Claudio Rapetto, Ferdinando Varbella, Bernardo Cortese, Gabriele Gabrielli, Salvatore Geraci, Bruno Loi, Giacomo Boccuzzi, Giuseppe Tarantini, Daniela Fischetti, Paolo Calabria, Fabrizio Tomai, Flavio Ribichini, Corrado Tamburino, Ciro Indolfi, Antonio L Bartorelli, Anna Sonia Petronio, Francesco Bedogni
AIMS: The present multicentre prospective study, IT-DISAPPEARS, was designed with the aim of evaluating early and long-term clinical outcomes of the Absorb BVS in patients with long coronary lesions and/or multivessel coronary artery disease. The aim of this article is to present the one-year clinical results of this study. METHODS AND RESULTS: Between November 2014 and January 2016, we enrolled 1,002 patients undergoing BVS implantation (long lesion [≥ 24 mm] of a single vessel in 80...
May 16, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28495897/geographical-difference-of-the-interaction-of-sex-with-treatment-strategy-in-patients-with-multivessel-disease-and-left-main-disease-a-meta-analysis-from-syntax-synergy-between-pci-with-taxus-and-cardiac-surgery-precombat-bypass-surgery-versus-angioplasty-using
#3
Yohei Sotomi, Yoshinobu Onuma, Rafael Cavalcante, Jung-Min Ahn, Cheol Whan Lee, David van Klaveren, Robbert J de Winter, Joanna J Wykrzykowska, Vasim Farooq, Marie-Claude Morice, Ewout W Steyerberg, Seung-Jung Park, Patrick W Serruys
BACKGROUND: The impact of sex on clinical outcomes of percutaneous coronary intervention and coronary artery bypass graft for patients with multivessel coronary disease and unprotected left main disease could be dissimilar between Western and Asian populations. METHODS AND RESULTS: To assess clinical outcomes after percutaneous coronary intervention or coronary artery bypass graft in women and men with multivessel coronary disease and unprotected left main disease, a pooled analysis (n=3280) was performed using the patient-level data from 3 large randomized trials: SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery), PRECOMBAT (Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease), and BEST (Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients with Multivessel Coronary Artery Disease) trials...
May 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28495431/evolution-of-australian-percutaneous-coronary-intervention-from-the-melbourne-interventional-group%C3%A2-mig-registry
#4
Julian Yeoh, Matias B Yudi, Nick Andrianopoulos, Bryan P Yan, David J Clark, Stephen J Duffy, Angela Brennan, Gishel New, Melanie Freeman, David Eccleston, Martin Sebastian, Christopher M Reid, William Wilson, Andrew E Ajani
Percutaneous coronary intervention (PCI) continues to evolve with shifting patient demographics, treatments, and outcomes. We sought to document the specific changes observed over a 9-year period in a contemporary Australian PCI cohort. The Melbourne Interventional Group is an established multicenter PCI registry in Melbourne, Australia. Data were collected prospectively with 30-day and 12-month follow-ups. Demographic, procedural, and outcome data for all consecutive patients were analyzed with a year-to-year comparison from 2005 to 2013...
April 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28471093/hybrid-coronary-revascularization-versus-coronary-artery-bypass-grafting-in-patients-with-multivessel-coronary-artery-disease-a-meta-analysis
#5
Partha Sardar, Amartya Kundu, Michelle Bischoff, Saurav Chatterjee, Theophilus Owan, Ramez Nairooz, Jay Giri, Michael E Halkos, Henry Liberman, John S Douglas, Debabrata Mukherjee
OBJECTIVES: This meta-analysis evaluated the effectiveness of hybrid coronary revascularization (HCR) compared to coronary artery bypass grafting (CABG) for the treatment of multivessel coronary artery disease (MVCAD). BACKGROUND: HCR involves a combination of surgical and percutaneous techniques, which in selected patients may present an alternative to conventional CABG. METHODS: Databases were searched through June 30, 2016, and studies comparing HCR with CABG for treatment of MVCAD were selected...
May 4, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28454806/assessing-micro-vascular-resistances-via-imr-to-predict-outcome-in-stemi-patients-with-multivessel-disease-undergoing-primary-pci-amicro-rationale-and-design-of-a-prospective-multicenter-clinical-trial
#6
Massimo Fineschi, Edoardo Verna, Giuseppe Mezzapelle, Davide Bartolini, Giovanni Turiano, Antonio Manari, Katia Lucarelli, Lucia Uguccioni, Alessandra Repetto, Giuseppe Tarantini
BACKGROUND: In STEMI patients treated with primary percutaneous coronary angioplasty (PPCI) the evaluation of coronary microcirculatory resistance index (IMR) predict the extent of microvascular damage and left ventricular (LV) remodeling. However, the impact of IMR on the clinical outcome after PPCI in patients with multivessel disease (MVD) remains unsettled. AIM: We designed a prospective multicenter controlled clinical trial to evaluate the prognostic value of IMR in terms of clinical outcome and left ventricular remodeling in STEMI patients with MVD undergoing PPCI...
May 2017: American Heart Journal
https://www.readbyqxmd.com/read/28449776/incident-myocardial-infarction-and-very-late-stent-thrombosis-in-outpatients-with%C3%A2-stable-coronary-artery-disease
#7
Gilles Lemesle, Olivier Tricot, Thibaud Meurice, Robert Lallemant, Maxence Delomez, Octave Equine, Nicolas Lamblin, Christophe Bauters
BACKGROUND: Current data are lacking for incidence, correlates, and prognosis associated with incident myocardial infarction (MI) in patients with stable coronary artery disease (CAD). Furthermore, the contribution of very late stent thrombosis (VLST) to these events remains poorly understood. OBJECTIVES: This study aimed to analyze the residual risk of MI, together with relevant associated factors, and related mortality in stable CAD outpatients. METHODS: The multicenter CORONOR (Suivi d'une cohorte de patients COROnariens stables en region NORd-Pas-de-Calais) study enrolled 4,184 unselected outpatients with stable CAD (i...
May 2, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28441643/ventricular-rupture-following-myocardial-infarction
#8
Christian Fielder Camm, Stefan Neubauer, David P Taggart, Oliver J Rider
A 70-year-old man presented with prolonged cardiac chest pain and was awaiting coronary artery bypass surgery following angiography showing extensive multivessel disease. Following further chest pain, cardiac magnetic resonance imaging showed extensive, contained, ventricular rupture, which was managed aggressively with combined bypass surgery and rupture repair.
May 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28431047/impact-of-the-syntax-scores-i-and-ii-in-patients-with-diabetes-and-multivessel-coronary-disease-a-pooled-analysis-of-patient-level-data-from-the-syntax-precombat-and-best-trials
#9
Rafael Cavalcante, Yohei Sotomi, Massimo Mancone, Cheol Whan Lee, Jung-Min Ahn, Yoshinobu Onuma, Pedro A Lemos, Robert-Jan van Geuns, Seung-Jung Park, Patrick W Serruys
Aims: To assess the impact of the SYNTAX scores I and II in outcomes after percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) for patients with diabetes and multivessel disease (MVD). Methods and Results: We performed a patient-level pooled analysis of three large randomized trials of patients with MVD. The impact of coronary anatomic complexity as measured by the SYNTAX score in the differences in outcomes following PCI and CABG was assessed at a median follow-up of 5 years...
April 18, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28429698/coronary-microvascular-dysfunction-equivalent-to-left-main-coronary-artery-disease
#10
Cafer Panç, Mehmet Kocaağa, Onur Erdoğan, Remzi Sarıkaya, Sabahattin Umman
Coronary microvascular dysfunction, also known as cardiac syndrome X, is a clinical syndrome presenting with typical angina and evidence of myocardial ischemia in the absence of flow-limiting stenosis on coronary angiography. Of patients undergoing coronary angiography due to suspected myocardial ischemia, 50% are found to have normal or near-normal coronary arteries. Described in this case report is a patient who developed hypotension and ST segment depressions during treadmill exercise test. Left main coronary artery or multivessel disease was suspected...
April 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28421591/-full-plastic-jacket-reconstruction-of-18-cm-of-coronary-arteries-with-bioresorbable-vascular-scaffolds-in-a-young-patient-with-st-elevation-myocardial-infarction-and-multivessel-disease
#11
Andrea Denegri, Antonio Halais Frangieh, Fabrizio D'Ascenzo, Jelena Rima Ghadri, Fabian Nietlispach, Christian Templin
No abstract text is available yet for this article.
2017: Cardiology Journal
https://www.readbyqxmd.com/read/28415731/gap-in-gender-parity-gender-disparities-in-incidence-and-clinical-impact-of-chronic-total-occlusion-in-non-infarct-artery-in-patients-with-non-st-segment-elevation-myocardial-infarction-and-multivessel-coronary-artery-disease
#12
Mateusz Tajstra, Michał Hawranek, Piotr Desperak, Aneta Ciślak, Mariusz Gąsior
A chronic total occlusion in a non-infarct-related artery is an independent predictor of mortality in non-ST elevation myocardial infarction. There are no mortality data about the impact of a chronic total occlusion in patients with non-ST elevation myocardial infarction according to gender. The purpose of this study was to evaluate the prevalence of the chronic total occlusion in in men and women and examine its impact on clinical outcomes. Data from consecutive patients with multivessel coronary artery disease treated in a high-volume center between 2006 and 2012 were included in a prospective registry and divided according to gender and the presence of chronic total occlusion...
March 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28409009/prognosis-of-complete-versus-incomplete-revascularisation-of-patients-with-stemi-with-multivessel-coronary-artery-disease-an-observational-study
#13
Aukelien C Dimitriu-Leen, Maaike P J Hermans, Caroline E Veltman, Bas L van der Hoeven, Alexander R van Rosendael, Erik W van Zwet, Martin J Schalij, Victoria Delgado, Jeroen J Bax, Arthur J H A Scholte
OBJECTIVE: The best strategy in patients with acute ST-segment elevation myocardial infarction (STEMI) with multivessel coronary artery disease (CAD) regarding completeness of revascularisation of the non-culprit lesion(s) is still unclear. To establish which strategy should be followed, survival rates over a longer period should be evaluated. The aim of this study was to investigate whether complete revascularisation, compared with incomplete revascularisation, is associated with reduced short-term and long-term all-cause mortality in patients with first STEMI and multivessel CAD...
2017: Open Heart
https://www.readbyqxmd.com/read/28404623/fractional-flow-reserve-guided-complete-revascularization-improves-the-prognosis-in-patients-with-st-segment-elevation-myocardial-infarction-and-severe-nonculprit-disease-a-danami-3-primulti-substudy-primary-pci-in-patients-with-st-elevation-myocardial-infarction
#14
Jacob Lønborg, Thomas Engstrøm, Henning Kelbæk, Steffen Helqvist, Lene Kløvgaard, Lene Holmvang, Frants Pedersen, Erik Jørgensen, Kari Saunamäki, Peter Clemmensen, Ole De Backer, Jan Ravkilde, Hans-Henrik Tilsted, Anton Boel Villadsen, Jens Aarøe, Svend Eggert Jensen, Bent Raungaard, Lars Køber, Dan Eik Høfsten
BACKGROUND: The impact of disease severity on the outcome after complete revascularization in patients with ST-segment-elevation myocardial infarction and multivessel disease is uncertain. The objective of this post hoc study was to evaluate the impact of number of diseased vessel, lesion location, and severity of the noninfarct-related stenosis on the effect of fractional flow reserve-guided complete revascularization. METHODS AND RESULTS: In the DANAMI-3-PRIMULTI study (Primary PCI in Patients With ST-Elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization), we randomized 627 ST-segment-elevation myocardial infarction patients to fractional flow reserve-guided complete revascularization or infarct-related percutaneous coronary intervention only...
April 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28400078/comparison-of-coronary-artery-bypass-grafting-and-drug-eluting-stents-in-patients-with-chronic-kidney-disease-and-multivessel-disease-a-meta-analysis
#15
Yushu Wang, Sui Zhu, Peijuan Gao, Qing Zhang
BACKGROUND: The optimal revascularization strategy of coronary artery bypass grafting (CABG) versus percutaneous coronary intervention with drug-eluting stent (PCI-DES) in patients with chronic kidney disease (CKD) and multivessel disease (MVD) remains unclear. METHODS: Pubmed, EMBASE and Cochrane Library electronic databases were searched from inception until June 2016. Studies that evaluate the comparative benefits of DES versus CABG in CKD patients with multi-vessel disease were considered for inclusion...
April 8, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28374179/revascularization-for-advanced-coronary-artery-disease-in-type-2-diabetic-patients-choosing-wisely-between-pci-and-surgery
#16
REVIEW
Louai Razzouk, Frederick Feit, Michael E Farkouh
PURPOSE OF REVIEW: Patients with type 2 diabetes mellitus (T2DM) are at an increased risk of systemic atherosclerosis and advanced coronary artery disease (CAD). Herein, we review clinical trials comparing surgical to percutaneous revascularization in the context of the unique pathophysiology in this patient population, and seek to answer the question of optimal strategy of revascularization. RECENT FINDINGS: Early studies showed a signal towards benefit of surgical revascularization over percutaneous revascularization in this group, but there was a paucity of randomized clinical trials (RCT) to directly support this finding...
May 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28367087/expression-of-sterol-regulatory-element-binding-proteins-in-epicardial-adipose-tissue-in-patients-with-coronary-artery-disease-and-diabetes-mellitus-preliminary-study
#17
Luis M Pérez-Belmonte, Inmaculada Moreno-Santos, Fernando Cabrera-Bueno, Gemma Sánchez-Espín, Daniel Castellano, Miguel Such, María G Crespo-Leiro, Fernando Carrasco-Chinchilla, Luis Alonso-Pulpón, Miguel López-Garrido, Amalio Ruiz-Salas, Víctor M Becerra-Muñoz, Juan J Gómez-Doblas, Eduardo de Teresa-Galván, Manuel Jiménez-Navarro
Objectives: Sterol regulatory element-binding proteins (SREBP) genes are crucial in lipid biosynthesis and cardiovascular homeostasis. Their expression in epicardial adipose tissue (EAT) and their influence in the development of coronary artery disease (CAD) and type-2 diabetes mellitus remain to be determined. The aim of our study was to evaluate the expression of SREBP genes in EAT in patients with CAD according to diabetes status and its association with clinical and biochemical data. Methods: SREBP-1 and SREBP-2 mRNA expression levels were measured in EAT from 49 patients with CAD (26 with diabetes) and 23 controls without CAD or diabetes...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28353317/self-expanding-stentys-stent-in-daily-routine-use
#18
Michał Kidawa, Krzysztof Chiżyński, Michał Kacprzak, Anna Ledakowicz-Polak, Marzenna Zielińska
In the era of modern interventional cardiology implantation of balloon expandable stent is a finishing touch of almost every coronary angioplasty. However sometimes we face clinical situation when decision on stent diameter is complicated, especially in ectatic part of arteries, in situations when artery lumen is obscured with thrombus or when reference diameter of proximal and distal part of lesion vary greatly. That is why idea of self-apposing stent similar to one used in peripheral vascular interventions was adopted into cardiology...
March 29, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28353212/stress-induced-alteration-of-left-ventricular-eccentricity-an-additional-marker-of-multivessel-cad
#19
Alessia Gimelli, Riccardo Liga, Assuero Giorgetti, Mirta Casagranda, Paolo Marzullo
BACKGROUND: Abnormal left ventricular (LV) eccentricity index (EI) is a marker of adverse cardiac remodeling. However, the interaction between stress-induced alterations of EI and major cardiac parameters has not been explored. We sought to evaluate the relationship between LV EI and coronary artery disease (CAD) burden in patients submitted to myocardial perfusion imaging (MPI). METHODS AND RESULTS: Three-hundred and forty-three patients underwent MPI and coronary angiography...
March 28, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28351907/frequency-predictors-and-implications-of-abnormal-blood-pressure-responses-during-dobutamine-stress-echocardiography
#20
Sara Abram, Adelaide M Arruda-Olson, Christopher G Scott, Patricia A Pellikka, Vuyisile T Nkomo, Jae K Oh, Alberto Milan, Mohamed M Abidian, Robert B McCully
BACKGROUND: It is not known whether abnormal blood pressure (BP) responses during dobutamine stress echocardiography (DSE) are associated with abnormal test results, nor if such results indicate obstructive coronary artery disease (CAD). We sought to define the frequency of abnormal BP responses during DSE and their impact on accuracy of test results. METHODS AND RESULTS: We studied 21 949 patients who underwent DSE at Mayo Clinic, Rochester, MN, grouped by peak systolic BP achieved during the test...
April 2017: Circulation. Cardiovascular Imaging
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