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Multivessel coronary artery disease

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https://www.readbyqxmd.com/read/28182034/topical-vasodilator-response-in-skeletonized-internal-mammary-artery-is-there-really-a-difference
#1
Syed Raza Shah, Syed Arbab Shah, Muhammad Ahmed Jangda, Mohammad Danial Yaqub, Ayesha Altaf Jangda, Maham Khan, Muhammad Asim Khan, Brian Tomkins
AIM OF THE STUDY: Coronary artery bypass graft surgery is the gold standard for the treatment of multivessel and left main coronary artery disease. However, there is considerable debate that whether left internal mammary artery (IMA) should be taken as pedicled or skeletonized. This study was conducted to assess the difference in blood flow after the application of topical vasodilator in skeletonized and pedicled IMA. MATERIALS AND METHODS: In this study, each patient underwent either skeletonized (n = 25) or pedicled IMA harvesting (n = 25)...
January 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28165613/outcomes-of-coronary-artery-bypass-graft-surgery-versus-drug-eluting-stents-in-older-adults
#2
Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
OBJECTIVES: Little data are available to compare coronary artery bypass graft surgery (CABG) vs percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in older adults. We evaluate the long-term outcomes of CABG vs PCI with DES in older adults with left main or multivessel coronary artery disease (CAD). DESIGN: Individual patient-level meta-analysis. SETTINGS: Databases from the BEST, PRECOMBAT, and SYNTAX trials were combined...
February 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28153633/comparison-of-the-presence-of-fragmented-qrs-complexes-in-the-inferior-versus-the-anterior-leads-for-predicting-coronary-artery-disease-severity
#3
Mehmet Eyuboglu, Ugur Kucuk, Omer Senarslan, Bahri Akdeniz
INTRODUCTION: Fragmented QRS complexes (fQRS) are a sign of myocardial scar and are associated with adverse outcomes and mortality in patients with coronary artery disease (CAD). However, little is known about the significance of fQRS or of their localization on electrocardiography (ECG) in patients without known CAD. We aimed to investigate the association between localization of fQRS on ECG and CAD severity in patients undergoing a first diagnostic coronary angiography. METHODS: We enrolled 135 consecutive patients who had a narrow fQRS on ECG and underwent a first diagnostic coronary angiography...
February 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28150287/complete-percutaneous-revascularization-feasibility-in-ischemic-heart-failure-is-related-to-improve-outcomes-insights-from-the-commit-hf-registry
#4
Łukasz Pyka, Michał Hawranek, Mateusz Tajstra, Jarosław Gorol, Andrzej Lekston, Mariusz Gąsior
BACKGROUND AND AIM: Heart failure (HF) is the major cause of death in cardiovascular disease. In a post-STICH landscape, we lack data on the role of percutaneous coronary intervention (PCI) in systolic HF patients. Complete revascularization remains a key unanswered question in ischemic HF. METHODS: The COMMIT-HF is an ongoing systolic HF registry (inclusion criteria: HF with left ventricular ejection fraction ≤35%, exclusion: acute coronary syndrome). A total of 1798 patients were enrolled...
February 2, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28129316/coronary-artery-disease-complexity-on-the-outcomes-of-a-staged-approach-of-pci-followed-by-minimally-invasive-valve-surgery
#5
Andrés M Pineda, Saqib A Gowani, Christos G Mihos, Ramesh Chandra, Orlando Santana, Joseph Lamelas, Nirat Beohar
OBJECTIVE: A staged approach of percutaneous coronary intervention (PCI) followed by minimally invasive valve surgery (MIVS) is an alternative to the combined coronary artery bypass graft and valve surgery for patients with concomitant coronary artery (CAD) and valvular heart disease. We sought to evaluate the impact of the complexity of CAD, as assessed by the Syntax score, on the outcomes of the staged approach. METHODS: We retrospectively evaluated 138 patients who underwent PCI and MIVS at our institution between January 2009 and June 2013...
January 27, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28121665/body-mass-index-carotid-plaque-and-clinical-outcomes-in-patients-with-coronary-artery-disease
#6
Hyun Woong Park, Ki-Hong Kim, In Girl Song, Taek-Geun Kwon, Wan Ho Kim, Jang-Ho Bae
OBJECTIVES: We evaluated the relationship among BMI, carotid sonographic findings, and long-term (5 years) cardiovascular events in Asian patients with coronary artery disease (CAD). PATIENTS AND METHODS: The study population consisted of 1342 consecutive patients with CAD, who were stratified into four groups according to weight status, as defined by the WHO for the Asian population: underweight (group I: BMI<18.5 kg/m, n=38); normal weight (group II: 18.5≤BMI<23...
January 31, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28112467/predictors-of-long-term-outcomes-after-bypass-grafting-versus-drug-eluting-stent-implantation-for-left-main-or-multivessel-coronary-artery-disease
#7
Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Minkyu Han, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
BACKGROUND: We assessed predictors of long-term outcomes after coronary artery bypass grafting (CABG) versus those after percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in 3,230 patients with left main or multivessel coronary artery disease (CAD). METHODS AND RESULTS: Data were pooled from the BEST, PRECOMBAT, and SYNTAX trials. Age, chronic kidney disease, chronic obstructive lung disease, left ventricular dysfunction, and peripheral arterial disease (PAD) were common predictors of all-cause mortality...
January 23, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28109574/revascularization-strategies-and-outcomes-in-elderly-patients-with-multivessel-coronary-disease
#8
J Trevor Posenau, Daniel M Wojdyla, Linda K Shaw, Karen P Alexander, E Magnus Ohman, Manesh R Patel, Peter K Smith, Sunil V Rao
BACKGROUND: Balancing risks and benefits of revascularization in elderly patients with multivessel coronary artery disease (CAD) is challenging. The appropriate revascularization strategy for elderly patients with multivessel CAD is unclear. METHODS: We used the Duke Databank for Cardiovascular Disease to identify patients aged 75 years or more who had multivessel disease and treatment with percutaneous coronary intervention or coronary artery bypass graft surgery (CABG) within 30 days of the index catheterization between October 1, 2003, and June 30, 2013...
January 18, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28100876/primary-percutaneous-coronary-intervention-followed-by-valve-surgery-for-acute-coronary-syndrome-at-left-main-trunk-complicated-with-severe-aortic-stenosis
#9
Akira Shikuma, Jun Shiraishi, Kazunari Okawa, Masaki Yashige, Keisuke Shoji, Daisuke Ito, Masayoshi Kimura, Eigo Kishita, Yusuke Nakagawa, Masayuki Hyogo, Akiyuki Takahashi, Takahisa Sawada
An 89-year-old woman appeared to have acute coronary syndrome at the left main trunk (LMT) complicated with severe aortic stenosis, moderate-severe mitral regurgitation, depressed left ventricular (LV) function, and multivessel disease. Because of sustained hypotension even under intra-aortic balloon pumping support during emergency coronary angiograhy, we performed primary percutaneous coronary intervention solely for the LMT lesion using a bare metal stent, leading to recovery from the shock state. On the second hospital day, based on our heart-team consensus, we performed aortic valve replacement and coronary artery bypass grafting surgery, and added edge-to-edge repair (Alfieri stitch) of the mitral valve, resulting in complete revascularization and dramatically improved LV function...
February 7, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28066641/completeness-of-revascularization-in-multivessel-coronary-artery-disease
#10
COMMENT
Yader Sandoval, Emmanouil S Brilakis, Santiago Garcia
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28066575/choosing-between-percutaneous-coronary-intervention-and-coronary-artery-bypass-graft-surgery-for-nondiabetic-patients-with-multivessel-disease
#11
EDITORIAL
Aeshita Dwivedi, Sripal Bangalore
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28063673/-coronary-artery-bypass-graft-surgery-with-bilateral-internal-mamary-artery-short-term-results
#12
Josías Caleb Ríos Ortega, Paul Castañeda Castillo, Luisa Talledo Paredes, Franz Soplopuco Palacios, Necemio Aranda Pretell, Yemmy Pérez Valverde, Julio Morón Castro, Andrés Reyes Torres
INTRODUCTION: Coronary artery bypass graft (CABG) surgery remains the gold standard in the treatment of multivessel coronary disease. Several studies have shown that CABG with bilateral internal mammary arteries (BIMA) has better results in long-term survival. METHODOLOGY: We conducted a retrospective investigation in CABG surgeries with BIMA, performed from January 2012 to December 2015 in the National Cardiovascular Institute, INCOR, EsSalud. The objectives were determine the mortality and major cardiovascular events at 30 days follow up...
January 4, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28057282/culprit-vessel-versus-multivessel-versus-in-hospital-staged-intervention-for-patients-with-st-segment-elevation-myocardial%C3%A2-infarction-and-multivessel-disease-stratified-analyses-in-high-risk-patient-groups-and-anatomic%C3%A2-subsets-of-nonculprit-disease
#13
M Bilal Iqbal, Imad J Nadra, Lillian Ding, Anthony Fung, Eve Aymong, Albert W Chan, Steven Hodge, Anthony Della Siega, Simon D Robinson
OBJECTIVES: This study evaluated revascularization strategies for patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease. BACKGROUND: In patients with STEMI and multivessel disease, it is unclear whether multivessel intervention (MVI), culprit vessel intervention (CVI) only (CVI-O) or CVI with staged revascularization (CVI-S) is associated with improved outcomes. Whether MVI at primary percutaneous coronary intervention may benefit specific patient groups is unclear...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28030655/percutaneous-coronary-intervention-with-bioresorbable-scaffolds-in-a-young-child
#14
Tamim M Nazif, Sanjog Kalra, Ziad A Ali, Dimitrios Karmpaliotis, Mariel E Turner, Thomas J Starc, Yang Cao, Charles C Marboe, Michael B Collins, Martin B Leon, Ajay J Kirtane
Importance: Although much less frequent than in adults, coronary artery disease requiring revascularization may develop in children because of homozygous familial hypercholesterolemia or other underlying conditions. Percutaneous coronary intervention (PCI) with a bioresorbable scaffold (BRS) may have advantages over metallic coronary stents in this population. Objective: To present a case of the successful treatment of unstable, multivessel coronary artery disease in a child with PCI with BRS implantation...
December 28, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/28029362/impact-of-multivessel-coronary-artery-disease-with-versus-without-left-main-coronary-artery-disease-on-long-term-mortality-after-coronary-bypass-grafting-versus-drug-eluting-stent-implantation
#15
Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
Limited data are available on the impact of concomitant left main coronary artery disease (CAD) on mortality after revascularization of multivessel coronary artery disease (MVD) alone or multivessel plus left main coronary artery disease (MVLMD). This study compared long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) with drug-eluting stents in 2,887 patients with MVD or MVLMD. Data were pooled from the BEST, PRECOMBAT, and SYNTAX trials. The primary outcome was death due to any cause...
15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28012553/comparison-of-percutaneous-coronary-intervention-versus-coronary-artery-bypass-grafting-for-unprotected-left-main-coronary-artery-disease
#16
REVIEW
Syed Yaseen Naqvi, Jordan Klein, Tisa Saha, Daniel J McCormick, Sheldon Goldberg
Coronary artery bypass grafting (CABG) decreases mortality in patients with significant left main (LM) coronary artery disease and for years remained the therapy of choice for patients with this ominous lesion. Advances in percutaneous coronary intervention (PCI) have enabled it to become an alternative to CABG. The results of observational registries and randomized comparisons have shown the safety and efficacy of PCI in appropriately selected patients with low or intermediate angiographic risk scores. Furthermore, the use of physiological measures of flow limitation and the use of intracoronary imaging techniques has added benefit and improved outcomes...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28007297/comparison-of-outcomes-of-staged-complete-revascularization-versus-culprit-lesion-only-revascularization-for-st-elevation-myocardial-infarction-and-multivessel-coronary-artery-disease
#17
Marcello Marino, Gabriele Crimi, Sergio Leonardi, Marco Ferlini, Alessandra Repetto, Rita Camporotondo, Andrea Demarchi, Ilaria De Pascali, Francesca Falcinella, Luigi Oltrona Visconti, Stefano De Servi, Maurizio Ferrario, Gaetano Maria De Ferrari, Massimiliano Gnecchi
The management of noninfarct-related arteries in patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary disease (MVD) is still debated. We evaluated the prognostic impact of staged complete revascularization with percutaneous coronary intervention (PCI) in STEMI patients with MVD admitted to our hospital from 2005 to 2013. Patients undergoing staged complete revascularization (n = 300) were compared with 1:1 propensity score-matched patients with culprit lesion-only treatment (n = 300)...
December 9, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28007199/coronary-artery-bypass-surgery-versus%C3%A2-drug-eluting-stent-implantation-for%C3%A2-left%C3%A2-main-or-multivessel-coronary-artery%C3%A2-disease-a-meta-analysis-of-individual-patient-data
#18
Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Pannipa Suwannasom, Erhan Tenekecioglu, Sung-Cheol Yun, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
OBJECTIVES: The authors undertook a patient-level meta-analysis to compare long-term outcomes after coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in 3,280 patients with left main or multivessel coronary artery disease (CAD). BACKGROUND: The relative efficacy and safety of CABG versus PCI with DES for left main or multivessel CAD remain controversial. METHODS: Data were pooled from the BEST (Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease), PRECOMBAT (Premier of Randomized Comparison of Bypass Surgery vs...
December 26, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27998824/plaque-surface-irregularity-and-calcification-length-within-carotid-plaque-predict-secondary-events-in-patients-with-coronary-artery-disease
#19
Shinichi Nonin, Shinichi Iwata, Kenichi Sugioka, Suwako Fujita, Naoki Norioka, Asahiro Ito, Masashi Nakagawa, Minoru Yoshiyama
BACKGROUND AND AIMS: Although comprehensive risk factor modification is recommended, a uniform management strategy does not necessarily prevent secondary events in patients with coronary artery disease (CAD). Therefore, identification of high-risk patients who may benefit from more intensive interventions may improve prognosis. Carotid ultrasound can reliably identify systemic atherosclerosis, and carotid plaque and intima-media thickness (IMT) are known independent risk factors for CAD...
January 2017: Atherosclerosis
https://www.readbyqxmd.com/read/27993757/percutaneous-intervention-in-chronic-total-coronary-occlusions-caused-by-in-stent-restenosis-procedural-results-and-long-term-clinical-outcomes-in-the-toro-spanish-registry-of-chronic-total-occlusion-secondary-to-an-occlusive-in-stent-restenosis-multicenter
#20
José M de la Torre Hernandez, José R Rumoroso, Asier Subinas, Nieves Gonzalo, Soledad Ojeda, Manuel Pan, Victoria Martín Yuste, Alfonso Suárez, Felipe Hernández, Luis Teruel, José Moreu, José M Cubero, José D Cascón, Hugo Vinhas, Íñigo Lozano, Javier Martin Moreiras, Armando Pérez de Prado, Javier Goicolea, Javier Escaned
AIMS: Limited data exist on the treatment and outcomes of patients with chronic total occlusions due to in-stent restenosis (CTO-ISR). We sought to evaluate results and clinical outcomes in percutaneous interventions over CTO-ISR. METHODS AND RESULTS: Registry in 16 centers involving consecutive patients undergoing attempt of percutaneous intervention over CTO-ISR. A total of 233 patients were included, 192 (82.4%) with successful acute result. Success rate was significantly lower in patients with: lesion in circumflex artery, ostial lesion, J score > 3 and no femoral access...
December 20, 2016: EuroIntervention
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