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https://www.readbyqxmd.com/read/28087483/cell-number-per-spheroid-and-electrical-conductivity-of-nanowires-influence-the-function-of-silicon-nanowired-human-cardiac-spheroids
#1
Yu Tan, Dylan Richards, Robert C Coyle, Jenny Yao, Ruoyu Xu, Wenyu Gou, Hongjun Wang, Donald R Menick, Bozhi Tian, Ying Mei
: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide an unlimited cell source to treat cardiovascular diseases, the leading cause of death worldwide. However, current hiPSC-CMs retain an immature phenotype that leads to difficulties for integration with adult myocardium after transplantation. To address this, we recently utilized electrically conductive silicon nanowires (e-SiNWs) to facilitate self-assembly of hiPSC-CMs to form nanowired hiPSC cardiac spheroids...
January 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28087139/retention-of-faculty-of-color-in-academic-nursing
#2
Nalo Hamilton, Emily A Haozous
BACKGROUND: Racial and ethnic diversity among nursing faculty is low, preventing schools of nursing (SON) from reflecting the populations that they serve academically and clinically. Few studies address the experience and success of faculty of color (FOC) in nursing. PURPOSE: The purpose of this article is to summarize the current literature related to FOC retention and promotion. METHODS: We reviewed 25 articles from the nursing literature following PRISMA guidelines, using a critical race theory framework...
December 8, 2016: Nursing Outlook
https://www.readbyqxmd.com/read/28081016/graphene-as-a-flexible-template-for-controlling-magnetic-interactions-between-metal-atoms
#3
Sungwoo Lee, Dongwook Kim, Alex W Robertson, Euijoon Yoon, Suklyun Hong, Jisoon Ihm, Jaejun Yu, Jamie H Warner, Gun-Do Lee
Metal-doped graphene produces magnetic moments that have potential application in spintronics. Here we use density function theory computational methods to show how the magnetic interaction between metal atoms doped in graphene can be controlled by the degree of flexure in a graphene membrane. Bending graphene by flexing causes the distance between two substitutional Fe atoms covalently bonded in graphene to gradually increase and these results in the magnetic moment disappearing at a critical strain value...
January 12, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28080305/critical-review-of-the-building-downwash-algorithms-in-aermod
#4
Ron L Petersen, Sergio Guerra, Anthony Bova
This paper documents theoretical and other problems in PRIME along with CFD simulations and wind tunnel observations that support these findings. While AERMOD/PRIME may provide accurate and unbiased estimates (within a factor of two) for some building configurations, a major review and update is needed so that accurate estimates can be obtained for other building configurations where significant overpredictions or underpredictions are common due to downwash effects. This will ensure that regulatory evaluations subject to dispersion modeling requirements can be based on an accurate model...
January 12, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28079226/in-silico-kinetics-of-alkaline-hydrolysis-of-1-3-5-trinitro-1-3-5-triazinane-rdx-m06-2x-investigation
#5
L K Sviatenko, L Gorb, D Leszczynska, S I Okovytyy, M K Shukla, J Leszczynski
Alkaline hydrolysis of RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine), as one of the most promising methods for nitrocompound remediation, was investigated computationally at the PCM(Pauling)/M06-2X/6-311++G(d,p) level of theory. Computational simulation shows that RDX hydrolysis is a highly exothermic multistep process involving initial deprotonation and nitrite elimination, cycle cleavage, further transformation of cycle-opened intermediates to end products caused by a series of C-N bond ruptures, hydroxide attachments, and proton transfers...
January 12, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28073338/microaggressions-and-daily-experience
#6
Anthony D Ong, Anthony L Burrow
Psychologists use the term microaggressions to describe subtle forms of bias and discrimination experienced by members of marginalized groups. Lilienfeld (2017, this issue) makes an important contribution to the literature by presenting a critical review of the meaning and measurement of microaggression experiences. In this commentary, we argue that advancing the construct of microaggressions rests on research approaches that move beyond static representations of individuals to dynamic frameworks that observe people's lives as they unfold day to day...
January 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28072543/nanoscale-nucleation-and-growth-of-electrodeposited-lithium-metal
#7
Allen Pei, Guangyuan Zheng, Feifei Shi, Yuzhang Li, Yi Cui
Lithium metal has re-emerged as an exciting anode for high energy lithium-ion batteries due to its high specific capacity of 3,860 mAh g(-1) and lowest electrochemical potential of all known materials. However, lithium has been plagued by the issues of dendrite formation, high chemical reactivity with electrolyte, and infinite relative volume expansion during plating and stripping, which present safety hazards and low cycling efficiency in batteries with lithium metal electrodes. There have been a lot of recent studies on Li metal although little work has focused on the initial nucleation and growth behavior of Li metal, neglecting a critical fundamental scientific foundation of Li plating...
January 10, 2017: Nano Letters
https://www.readbyqxmd.com/read/28072462/reliability-of-the-electrocortical-response-to-gains-and-losses-in-the-doors-task
#8
Amanda R Levinson, Brittany C Speed, Zachary P Infantolino, Greg Hajcak
The ability to differentiate between rewards and losses is critical for motivated action, and aberrant reward and loss processing has been associated with psychopathology. The reward positivity (RewP) and feedback negativity (FN) are ERPs elicited by monetary gains and losses, respectively, and are promising individual difference measures. However, few studies have reported on the psychometric properties of the RewP and FN-crucial characteristics necessary for valid individual difference measures. The current study examined the internal consistency and 1-week test-retest reliability of the RewP and FN as elicited by the doors task among 59 young adults...
January 10, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28070932/the-experience-of-adult-children-of-mothers-with-intellectual-disability-a-qualitative-retrospective-study-from-poland
#9
Agnieszka Wołowicz-Ruszkowska, David McConnell
BACKGROUND: Little is known about the experience of growing up with a mother with intellectual disability. The aim of this study was to explore this experience from the perspective of adult children. METHOD: In-depth interviews with 23 adult children brought up by mothers with moderate-to-severe intellectual disability. The interview data were analysed using grounded theory methods. RESULTS: The childhood experiences of the interviewees and the role their mothers played in their upbringing varied, depending in part on the involvement of extended family...
January 10, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28069045/improving-nursing-home-care-through-feedback-on-performance-data-inform-protocol-for-a-cluster-randomized-trial
#10
Matthias Hoben, Peter G Norton, Liane R Ginsburg, Ruth A Anderson, Greta G Cummings, Holly J Lanham, Janet E Squires, Deanne Taylor, Adrian S Wagg, Carole A Estabrooks
BACKGROUND: Audit and feedback is effective in improving the quality of care. However, methods and results of international studies are heterogeneous, and studies have been criticized for a lack of systematic use of theory. In TREC (Translating Research in Elder Care), a longitudinal health services research program, we collect comprehensive data from care providers and residents in Canadian nursing homes to improve quality of care and life of residents, and quality of worklife of caregivers...
January 10, 2017: Trials
https://www.readbyqxmd.com/read/28069014/cultural-elements-underlying-the-community-health-representative-client-relationship-on-navajo-nation
#11
Vikas Gampa, Casey Smith, Olivia Muskett, Caroline King, Hannah Sehn, Jamy Malone, Cameron Curley, Chris Brown, Mae-Gilene Begay, Sonya Shin, Adrianne Katrina Nelson
BACKGROUND: Navajo Nation Community Health Representatives (CHR) are trained community health workers (CHWs) who provide crucial services for patients and families. The success of the CHRs' interventions depends on the interactions between the CHRs and their clients. This research investigates the culturally specific factors that build and sustain the CHR-client interaction. METHODS: In-depth interviews were conducted with 16 CHRs on Navajo Nation. Interviews were transcribed and coded according to relevant themes...
January 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28068516/a-dft-study-on-the-complex-formation-between-desferrithiocin-and-metal-ions-mg-2-al-3-ca-2-mn-2-fe-3-co-2-ni-2-cu-2-zn-2
#12
Sadegh Kaviani, Mohammad Izadyar, Mohammad Reza Housaindokht
In recent years, Metal-chelating compounds, namely siderphores have been considered very much because of their crucial role in various fields of the environmental researches. Their importance lies in the fact that they are able to be bonded to a variety of metals in addition to iron. A theoretical study on the structures of desferrithiocin siderphore coordinated to Mg(2+), Al(3+), Ca(2+), Mn(2+), Fe(3+), Co(2+), Ni(2+), Cu(2+) and Zn(2+) metal ions was carried out, using the CAM-B3LYP/6-31G(d) level of the theory in the water...
January 3, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28068468/aggregation-kinetics-and-self-assembly-mechanisms-of-graphene-quantum-dots-in-aqueous-solutions-cooperative-effects-of-ph-and-electrolytes
#13
Qingqing Li, Baoliang Chen, Baoshan Xing
The cooperative effects of pH and electrolytes on the aggregation of GQDs and the aggregate morphologies are characterized. Because GQDs have an average size of 9 nm with abundant O-functionalized edges, their suspension was very stable even in a high electrolyte concentration and low pH solution. Divalent cations (Mg2+ and Ca2+) exceled at aggregating the GQD nanoplates, while monovalent cations (Na+ and K+) did not disturb the stability. For Na+ and K+, positive linear correlations were observed between the critical coagulation concentration (CCC) and pH levels...
January 9, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28068459/does-pharmacogenomic-testing-improve-clinical-outcomes-for-major-depressive-disorder-a-systematic-review-of-clinical-trials-and-cost-effectiveness-studies
#14
Joshua D Rosenblat, Yena Lee, Roger S McIntyre
OBJECTIVE: Pharmacogenomic testing has become scalable and available to the general public. Pharmacogenomics has shown promise for predicting antidepressant response and tolerability in the treatment of major depressive disorder (MDD). In theory, pharmacogenomics can improve clinical outcomes by guiding antidepressant selection and dosing. The current systematic review examines the extant literature to determine the impact of pharmacogenomic testing on clinical outcomes in MDD and assesses its cost-effectiveness...
January 3, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28068295/support-vector-machines-to-detect-physiological-patterns-for-eeg-and-emg-based-human-computer-interaction-a-review
#15
L R Quitadamo, F Cavrini, L Sbernini, F Riillo, L Bianchi, S Seri, G Saggio
Support vector machines (SVMs) are widely used classifiers for detecting physiological patterns in human-computer interaction (HCI). Their success is due to their versatility, robustness and large availability of free dedicated toolboxes. Frequently in the literature, insufficient details about the SVM implementation and/or parameters selection are reported, making it impossible to reproduce study analysis and results. In order to perform an optimized classification and report a proper description of the results, it is necessary to have a comprehensive critical overview of the applications of SVM...
January 9, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28064526/understanding-social-norms-and-violence-in-childhood-theoretical-underpinnings-and-strategies-for-intervention
#16
P S Lilleston, L Goldmann, R K Verma, J McCleary-Sills
Violence in childhood is a widespread human rights violation that crosses cultural, social and economic lines. Social norms, the shared perceptions about others that exist within social groups, are a critical driver that can either prevent or perpetuate violence in childhood. This review defines injunctive and descriptive social norms and lays out a conceptual framework for the relationship between social norms and violence in childhood, including the forces shaping social norms, the mechanisms through which these norms influence violence in childhood (e...
January 9, 2017: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/28064109/interagency-collaboration-strengthening-substance-abuse-resources-in-child-welfare
#17
Amy S He, Jon Phillips
Supporting child welfare (CW) workers' ability to accurately assess substance abuse needs and link families to appropriate services is critical given the high prevalence of parental substance use disorders (SUD) among CW-involved cases. Several barriers hinder this process, including CW workers' lack of expertise for identifying SUD needs and scarcity of treatment resources. Drawing from theories and emergent literature on interagency collaboration, this study examined the role of collaboration in increasing the availability of resources for identifying and treating SUDs in CW agencies...
January 5, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28063432/is-sodium-a-superconductor-under-high-pressure
#18
Roxanne Tutchton, Xiaojia Chen, Zhigang Wu
Superconductivity has been predicted or measured for most alkali metals under high pressure, but the computed critical temperature (Tc) of sodium (Na) at the face-centered cubic (fcc) phase is vanishingly low. Here we report a thorough, first-principles investigation of superconductivity in Na under pressures up to 260 GPa, where the metal-to-insulator transition occurs. Linear-response calculations and density functional perturbation theory were employed to evaluate phonon distributions and the electron-phonon coupling for bcc, fcc, cI16, and tI19 Na...
January 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28061328/calcium-hypothesis-of-alzheimer-s-disease-and-brain-aging-a%C3%A2-framework-for-integrating-new-evidence-into-a-comprehensive-theory-of-pathogenesis
#19
(no author information available yet)
This article updates the Calcium Hypothesis of Alzheimer's disease and brain aging on the basis of emerging evidence since 1994 (The present article, with the subtitle "New evidence for a central role of Ca(2+) in neurodegeneration," includes three appendices that provide context and further explanations for the rationale for the revisions in the updated hypothesis-the three appendices are as follows: Appendix I "Emerging concepts on potential pathogenic roles of [Ca(2+)]," Appendix II "Future studies to validate the central role of dysregulated [Ca(2+)] in neurodegeneration," and Appendix III "Epilogue: towards a comprehensive hypothesis...
January 3, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28060507/combining-internally-contracted-states-and-matrix-product-states-to-perform-multireference-perturbation-theory
#20
Sandeep Sharma, Gerald Knizia, Sheng Guo, Ali Alavi
We present two efficient and intruder-free methods for treating dynamic correlation on top of general multi-configuration reference wave functions---including such as obtained by the density matrix renormalization group (DMRG) with large active spaces. The new methods are the second order variant of the recently proposed multi-reference linearized coupled cluster method (MRLCC) [S. Sharma, A. Alavi, J. Chem. Phys. 143, 102815 (2015)], and of N-electron valence perturbation theory (NEVPT2), with expected accuracies similar to MRCI+Q and (at least) CASPT2, respectively...
January 6, 2017: Journal of Chemical Theory and Computation
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