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https://www.readbyqxmd.com/read/28528268/optimistic-honesty-understanding-surgeon-and-patient-perspectives-on-hopeful-communication-in-pancreatic-cancer-care
#1
Kim Blakely, Paul J Karanicolas, Frances C Wright, Lesley Gotlib Conn
BACKGROUND: Prognosis conversations between surgical oncologists and patients with pancreatic cancer are critically important and challenging. Surgeons and their patients often have discrepant understandings of prognosis despite extensive conversations. Little is known about how surgeons approach prognosis conversations with these patients; patients' experiences with these conversations are also not well understood. This qualitative study sought to better understand surgeon and patient perspectives on communication in pancreatic cancer care with a view toward improvement...
May 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28527441/an-assessment-of-low-lying-excitation-energies-and-triplet-instabilities-of-organic-molecules-with-an-ab-initio-bethe-salpeter-equation-approach-and-the-tamm-dancoff-approximation
#2
Tonatiuh Rangel, Samia M Hamed, Fabien Bruneval, Jeffrey B Neaton
The accurate prediction of singlet and triplet excitation energies is an area of intense research of significant fundamental interest and critical for many applications. Most calculations of singlet and triplet energies use time-dependent density functional theory (TDDFT) in conjunction with an approximate exchange-correlation functional. In this work, we examine and critically assess an alternative method for predicting low-lying neutral excitations with similar computational cost, the ab initio Bethe-Salpeter equation (BSE) approach, and compare results against high-accuracy wavefunction-based methods...
May 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28527377/fishing-for-leadership-the-role-diversification-plays-in-facilitating-change-agents
#3
Joshua S Stoll
Leadership is often viewed as being critical to successful natural resource management. This research focuses on a set of leaders identified through a social network analysis of fishers in a rural coastal region. Leaders' connections to different fisheries are evaluated, and these actors are found to be significantly more diversified than other fishers in the area. Drawing on theory related to institutional entrepreneurship and a series of in-depth interviews with these actors, this paper puts forward several hypotheses to explain how diverse social-ecological connections facilitate leadership...
May 17, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28526979/the-probabilities-of-one-and-multi-track-events-for-modeling-radiation-induced-cell-kill
#4
Uwe Schneider, Fabiano Vasi, Jürgen Besserer
In view of the clinical importance of hypofractionated radiotherapy, track models which are based on multi-hit events are currently reinvestigated. These models are often criticized, because it is believed that the probability of multi-track hits is negligible. In this work, the probabilities for one- and multi-track events are determined for different biological targets. The obtained probabilities can be used with nano-dosimetric cluster size distributions to obtain the parameters of track models. We quantitatively determined the probabilities for one- and multi-track events for 100, 500 and 1000 keV electrons, respectively...
May 19, 2017: Radiation and Environmental Biophysics
https://www.readbyqxmd.com/read/28526695/-thinking-ethics-a-novel-pilot-proof-of-concept-program-of-integrating-ethics-into-the-physiology-curriculum-in-south-india
#5
Savitha D, Manjulika Vaz, Mario Vaz
Integrating medical ethics into the physiology teaching-learning program has been largely unexplored in India. The objective of this exercise was to introduce an interactive and integrated ethics program into the Physiology course of first-year medical students and to evaluate their perceptions. Sixty medical students (30 men, 30 women) underwent 11 sessions over a 7-mo period. Two of the Physiology faculty conducted these sessions (20-30 min each) during the routine physiology (theory/practicals) classes that were of shorter duration and could, therefore, accommodate the discussion of related ethical issues...
June 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28525718/on-the-stability-of-the-parent-anion-of-the-potential-radiosensitizer-8-bromoadenine-formed-by-low-energy-3-ev-electron-attachment
#6
Robin Schürmann, Katrin Tanzer, Iwona Dabkowska, Stephan Paul Denifl, Ilko Bald
8-Bromoadenine (8BrA) is a potential DNA radiosensitizer for cancer radiation therapy due to its efficient interaction with low energy electrons (LEEs). LEEs are a short-living species generated during the radiation damage of DNA by high energy radiation as it is applied in cancer radiation therapy. Electron attachment to 8BrA in the gas phase results in a stable parent anion below 3 eV electron energy in addition to fragmentation products formed by resonant exocyclic bond cleavages. Density functional theory (DFT) calculations of the 8BrA- anion reveal an exotic bond between the bromine and the C8 atom with a bond length of 2...
May 19, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28524690/new-easy-plane-cp-n-1-fixed-points
#7
Jonathan D'Emidio, Ribhu K Kaul
We study fixed points of the easy-plane CP^{N-1} field theory by combining quantum Monte Carlo simulations of lattice models of easy-plane SU(N) superfluids with field theoretic renormalization group calculations, by using ideas of deconfined criticality. From our simulations, we present evidence that at small N our lattice model has a first-order phase transition which progressively weakens as N increases, eventually becoming continuous for large values of N. Renormalization group calculations in 4-ε dimensions provide an explanation of these results as arising due to the existence of an N_{ep} that separates the fate of the flows with easy-plane anisotropy...
May 5, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28521557/metacognitive-verb-production-in-adolescents-the-link-to-complex-syntax
#8
Marilyn A Nippold, Laura M Vigeland, Megan W Frantz-Kaspar
Metacognitive verbs (MCVs) such as believe, know and think allow a speaker to describe the thoughts, feelings and perspectives of the self and others. As such, these words reflect the speaker's awareness of differing mental events and activities, or Theory of Mind (ToM). This study investigated the use of MCVs in adolescents with typical language development in relation to the production of complex sentences. It was of interest to determine the frequency with which adolescents used MCVs and to explore the links between MCVs and different types of subordinate clauses...
May 19, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28521086/a-computational-exploration-of-h2s-and-co2-capture-by-ionic-liquids-based-on-%C3%AE-amino-acid-anion-and-n7-n9-dimethyladeninium-cation
#9
Badrosadat Seyedhosseini, Mohammad Izadyar, Mohammad Reza Housaindokht
Hydrogen sulfide (H2S) and carbon dioxide (CO2) adsorption on a series of the aliphatic amino acid ionic liquids (AAILs) composed of N7,N9- dimethyladeninium cation with amino acid anions (AA= Gly, Ala, Val, Leu and Ile) as the functionalized ILs with dual groups of amine have been investigated. Based on the obtained data, the possible sites of H2S adsorption are twice as CO2 on the ionic liquids and also the average adsorption energy of H2S (∆E=-51.5 kJ.mol-1) in the most stable region of adsorption is twice greater than that of CO2 (∆E=-25...
May 18, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28520447/-controversies-around-qalys
#10
Vladimír Rogalewicz, Miroslav Barták
The paper summarizes the criticisms of the QALY concept utilization in health-economic evaluations that has been growing stronger in the last years. Despite of its limitations, the QALY concept has been routinely used in many countries incl. the Czech Republic. However, some states disapproved QALYs as an optimizing criterion at the level of their political decisions. The critical reflection concerns both the theoretical and the experimental issues. Based on a literary review, fundamental arguments against the concept are summarized, and a synthesis of material objections is presented...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28520433/toward-a-rigorous-definition-of-a-strength-of-any-interaction-between-bader-s-atomic-basins
#11
Ivan V Ananyev, Valentina A Karnoukhova, Artem O Dmitrienko, Konstantin A Lyssenko
Strength of interaction between Bader's atomic basins, enclosed by zero-flux surfaces of electron distribution, was proposed to be a measure of elastic deformation of an interaction. The set containing 53 atomic aggregate and covering all range of interaction strength (from van-der-Waals interactions to triple covalent bonds) was calculated by DFT and perturbation theory methods. Further analysis was performed to seek correlations between various local quantities based on electron density and effective force constants of stretching diatomic vibrations...
May 18, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28517968/a-community-based-qualitative-study-of-intergenerational-resilience-with-palestinian-refugee-families-facing-structural-violence-and-historical-trauma
#12
Devin G Atallah
The purpose of this study was to explore resilience processes in Palestinian refugee families living under Israeli occupation for multiple generations. Qualitative methods, critical postcolonial theories, and community-based research approaches were used to examine intergenerational protective practices and to contribute to reconceptualizations of resilience from indigenous perspectives. First, the researcher developed a collaborative partnership with a nongovernmental organization (NGO) in a UN refugee camp in the occupied West Bank...
January 1, 2017: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28516394/linguistic-asymmetry-egocentric-anchoring-and-sensory-modality-as-factors-for-the-observed-association-between-time-and-space-perception
#13
Eunice E Hang Choy, Him Cheung
Temporal and spatial representations have been consistently shown to be inextricably intertwined. However, the exact nature of time-space mapping remains unknown. On the one hand, the conceptual metaphor theory postulates unilateral, asymmetric mapping of time onto space, that is, time is perceived in spatial terms but the perception of space is relatively independent of time. On the other hand, a theory of magnitude assumes bilateral and symmetric interactions between temporal and spatial perceptions. In the present paper, we argue that the concepts of linguistic asymmetry, egocentric anchoring, and sensory modality provide potential explanations for why evidences favoring both asymmetry and symmetry have been obtained...
May 17, 2017: Cognitive Processing
https://www.readbyqxmd.com/read/28516127/a-pilot-study-for-linking-adolescent-patients-to-an-interactive-tobacco-prevention-program
#14
Karen S Calabro, Salma K Marani, Thuan A Le, Georges E Khalil, Irene M Tami-Maury, Alexander V Prokhorov
CONTEXT: The American Academy of Pediatrics and professional guidelines recommend intervening with adolescents about avoiding tobacco use in the health-care setting. Barriers in the clinical setting limit consistent provision of this critical service. OBJECTIVES: This pilot study compared 2 approaches for referring adolescents to an evidence-based tobacco prevention and cessation program in the outpatient setting. Secondary aims assessed tobacco use, knowledge, and program evaluation...
January 2017: Health Services Research and Managerial Epidemiology
https://www.readbyqxmd.com/read/28515688/insulin-resistance-as-a-link-between-amyloid-beta-and-tau-pathologies-in-alzheimer-s-disease
#15
Roger J Mullins, Thomas C Diehl, Chee W Chia, Dimitrios Kapogiannis
Current hypotheses and theories regarding the pathogenesis of Alzheimer's disease (AD) heavily implicate brain insulin resistance (IR) as a key factor. Despite the many well-validated metrics for systemic IR, the absence of biomarkers for brain-specific IR represents a translational gap that has hindered its study in living humans. In our lab, we have been working to develop biomarkers that reflect the common mechanisms of brain IR and AD that may be used to follow their engagement by experimental treatments...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28515313/low-temperature-nullifies-the-circadian-clock-in-cyanobacteria-through-hopf-bifurcation
#16
Yoriko Murayama, Hiroshi Kori, Chiaki Oshima, Takao Kondo, Hideo Iwasaki, Hiroshi Ito
Cold temperatures lead to nullification of circadian rhythms in many organisms. Two typical scenarios explain the disappearance of rhythmicity: the first is oscillation death, which is the transition from self-sustained oscillation to damped oscillation that occurs at a critical temperature. The second scenario is oscillation arrest, in which oscillation terminates at a certain phase. In the field of nonlinear dynamics, these mechanisms are called the Hopf bifurcation and the saddle-node on an invariant circle bifurcation, respectively...
May 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28513739/vapour-liquid-interfacial-properties-of-square-well-chains-from-density-functional-theory-and-monte-carlo-simulation
#17
Francisco José Martínez-Ruiz, Felipe J Blas, A Ignacio Moreno-Ventas Bravo, José Manuel Míguez, Luis G MacDowell
The statistical associating fluid theory for attractive potentials of variable range (SAFT-VR) density functional theory (DFT) developed by [Gloor et al., J. Chem. Phys., 2004, 121, 12740-12759] is used to predict the interfacial behaviour of molecules modelled as fully-flexible square-well chains formed from tangentially-bonded monomers of diameter σ and potential range λ = 1.5σ. Four different model systems, comprising 4, 8, 12, and 16 monomers per molecule, are considered. In addition to that, we also compute a number of interfacial properties of molecular chains from direct simulation of the vapour-liquid interface...
May 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28513191/the-antecedents-and-outcomes-of-dyadic-coping-in-close-personal-relationships-a-systematic-review-and-narrative-synthesis
#18
Helen R Staff, Faye F Didymus, Susan H Backhouse
BACKGROUND AND OBJECTIVES: Theories of dyadic coping and empirical literature have intermittently and inconsistently highlighted antecedents and outcomes of dyadic coping. The purpose of this review was to systematically identify the antecedents and outcomes of dyadic coping in close personal relationships. DESIGN: A PRISMA-guided systematic review and narrative synthesis. METHODS: Literature searches were conducted using CINAHL, PubMed, PsycINFO, and citation pearl growing to identify studies that were relevant to the aim of the review...
May 17, 2017: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/28512309/triplet-cooper-pairs-induced-in-diffusive-s-wave-superconductors-interfaced-with-strongly-spin-polarized-magnetic-insulators-or-half-metallic-ferromagnets
#19
Jabir Ali Ouassou, Avradeep Pal, Mark Blamire, Matthias Eschrig, Jacob Linder
Interfacing superconductors with strongly spin-polarized magnetic materials opens the possibility to discover new spintronic devices in which spin-triplet Cooper pairs play a key role. Motivated by the recent derivation of spin-polarized quasiclassical boundary conditions capable of describing such a scenario in the diffusive limit, we consider the emergent physics in hybrid structures comprised of a conventional s-wave superconductor (e.g. Nb, Al) and either strongly spin-polarized ferromagnetic insulators (e...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28512221/shear-bands-as-manifestation-of-a-criticality-in-yielding-amorphous-solids
#20
Giorgio Parisi, Itamar Procaccia, Corrado Rainone, Murari Singh
Amorphous solids increase their stress as a function of an applied strain until a mechanical yield point whereupon the stress cannot increase anymore, afterward exhibiting a steady state with a constant mean stress. In stress-controlled experiments, the system simply breaks when pushed beyond this mean stress. The ubiquity of this phenomenon over a huge variety of amorphous solids calls for a generic theory that is free of microscopic details. Here, we offer such a theory: The mechanical yield is a thermodynamic phase transition, where yield occurs as a spinodal phenomenon...
May 16, 2017: Proceedings of the National Academy of Sciences of the United States of America
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