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https://www.readbyqxmd.com/read/29346436/bone-marrow-concentrate-promotes-bone-regeneration-with-a-suboptimal-dose-of-rhbmp-2
#1
Kazuhiro Egashira, Yoshinori Sumita, Weijian Zhong, Takashi I, Seigo Ohba, Kazuhiro Nagai, Izumi Asahina
Bone marrow concentrate (BMC), which is enriched in mononuclear cells (MNCs) and platelets, has recently attracted the attention of clinicians as a new optional means for bone engineering. We previously reported that the osteoinductive effect of bone morphogenetic protein-2 (BMP-2) could be enhanced synergistically by co-transplantation of peripheral blood (PB)-derived platelet-rich plasma (PRP). This study aims to investigate whether BMC can effectively promote bone formation induced by low-dose BMP-2, thereby reducing the undesirable side-effects of BMP-2, compared to PRP...
2018: PloS One
https://www.readbyqxmd.com/read/29338274/frequency-and-correlation-of-lip-prints-fingerprints-and-abo-blood-groups-in-population-of-sriganganagar-district-rajasthan
#2
Harpreet Sandhu, Pradhuman Verma, Sarfaraz Padda, Seetharamaiha Sunder Raj
OBJECTIVE: To investigate the frequency and uniqueness of different lip print patterns, fingerprint patterns in relation to gender and ABO Rh blood groups among a semi-urban population of Sriganganagar, Rajasthan. MATERIALS AND METHODS: The study was conducted on 1200 healthy volunteers aged 18-30 years. The cheiloscopic and dermatographic data of each subject were obtained and were analysed according to the Suzuki and Tsuchihashi and Henry systems of classification, respectively...
November 2017: Acta Medica Academica
https://www.readbyqxmd.com/read/29336112/is-there-an-association-of-abo-blood-groups-and-rhesus-factor-with-alopecia-areata
#3
Zeynep Gizem Kaya İslamoğlu, Mehmet Unal
BACKGROUND/OBJECTIVES: Alopecia areata (AA) is an autoimmune disease characterized by noncicatricial hair loss localized on hair, beard, mustache, eyebrow, eyelash, and sometimes on the body. Although etiopathogenesis is not fully understood, many studies show remarkable associations between various diseases and ABO blood groups. However, there is no study with AA and blood groups. METHODS: Healthy people and patients with AA were included in this study. A total of 155 patients with AA and 299 healthy controls were included in the study...
January 15, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29335464/evaluation-of-endothelial-function-by-vop-and-inflammatory-biomarkers-in-patients-with-arterial-hypertension
#4
Camillo L C Junqueira, Maria Eliane C Magalhães, Andréa Araújo Brandão, Esmeralci Ferreira, Adriana S M Junqueira, José Firmino N Neto, Maria das Graças C Souza, Daniel Alexandre Bottino, Eliete Bouskela
Hypertension is associated with microcirculatory impairment. Our objectives were to evaluate endothelial function and inflammatory biomarkers in patients with resistant (RH) and mild to moderate (MMH) arterial hypertension in comparison to normotensives (control group-CG). Three groups, 25 patients each, have been investigated, by anamnesis, venous occlusion plethysmography (VOP) and serum determination of adhesion molecules (VCAM, ICAM), adiponectin, endothelin and C-reactive protein (CRP). Patients not using statins and with or without blood pressure control were also analyzed...
January 15, 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29330014/frequency-of-red-blood-cell-genotypes-in-multi-transfused-patients-and-blood-donors-from-minas-gerais-southeast-brazil
#5
Vitor Mendonça Alves, Fernanda Bernadelli De Vito, Paulo Roberto Juliano Martins, Sheila Soares Silva, Lilian Castilho, Helio Moraes-Souza
BACKGROUND AND OBJECTIVES: The frequency of red blood cell (RBC) antigens in Brazil varies due to differences in the ethnic groups in different regions; however, these studies have not been performed in Minas Gerais, where African admixture is more prevalent in comparison with other states. Due to these facts, this study aimed to determine the frequency of RBC genotypes on Rh, Kell, Duffy and Kidd systems in blood donors and multi-transfused patients from Minas Gerais, Southeast Brazil...
December 16, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29328528/evaluation-of-the-use-of-recombinant-human-basic-fibroblast-growth-factor-in-combination-with-negative-pressure-wound-therapy-with-instillation-and-dwell-time-in-porcine-full-thickness-wound-model
#6
Hiroto Saijo, Deepak V Kilpadi, Sadanori Akita
NPWT with instillation and dwell time (NPWTi-d), which combines NPWT with wound irrigation, has been clinically applied as a more effective treatment than conventional NPWT. Commercially available recombinant human basic fibroblast growth factor (rh-bFGF) has been demonstrated to be beneficial for use over the wound beds. The objective of this study was to evaluate the effectiveness of combined treatment with NPWTi-d and rh-bFGF. Six pigs received 12 full-thickness excisional skin wounds and were treated with 6 different treatment groups for each pair...
January 12, 2018: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29319244/seroprevalence-of-toxoplasma-gondii-among-pregnant-women-in-northeast-india
#7
Biswajyoti Borkakoty, Dipankar Biswas, Aniruddha Jakharia, Jagadish Mahanta
Objective: Toxoplasma gondii infection is primarily asymptomatic and one third of world's population is estimated to be infected by this protozoan parasite. This study was carried out to determine the seroprevalence of T. gondii infection among pregnant women from north east India, where data on this important parasitic infection is scanty. Methods: A total of 1141 serum archival samples collected from antenatal clinic attendees in 2007-09, were screened for T. gondii IgG by ELISA and analyzed with their socio demographic information...
October 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29296782/whole-exome-sequencing-for-rh-genotyping-and-alloimmunization-risk-in-children-with-sickle-cell-anemia
#8
Stella T Chou, Jonathan M Flanagan, Sunitha Vege, Naomi L C Luban, R Clark Brown, Russell E Ware, Connie M Westhoff
RH genes are highly polymorphic and encode the most complex of the 35 human blood group systems. This genetic diversity contributes to Rh alloimmunization in patients with sickle cell anemia (SCA) and is not avoided by serologic Rh-matched red cell transfusions. Standard serologic testing does not distinguish variant Rh antigens. Single nucleotide polymorphism (SNP)-based DNA arrays detect many RHD and RHCE variants, but the number of alleles tested is limited. We explored a next-generation sequencing (NGS) approach using whole-exome sequencing (WES) in 27 Rh alloimmunized and 27 matched non-alloimmunized patients with SCA who received chronic red cell transfusions and were enrolled in a multicenter study...
August 8, 2017: Blood Advances
https://www.readbyqxmd.com/read/29288728/the-rs243866-243865-polymorphisms-in-mmp-2-gene-and-the-relationship-with-bp-control-in-obese-resistant-hypertensive-subjects
#9
Alessandra M V Ritter, Ana Paula de Faria, Natália R Barbaro, Andréa R Sabbatini, Nathália Batista Corrêa, Veridiana Brunelli, Andre Fattoni, Rivadavio Amorim, Rodrigo Modolo, Heitor Moreno
We sought to investigate whether the polymorphisms rs243865 (-1306C>T); rs243866 (-1575G>A) and rs2285053 (-735C>T) in metalloproteinases 2 - MMP-2 gene and rs17576 (Q279R), rs17577 (Q668R) and rs3918242 (-1562C>T) in MMP-9 gene are associated with clinical outcomes in obese resistant hypertensive (RH) subjects. One hundred and twenty RH were enrolled in this cross-sectional study and divided into obese (n=63) and non-obese (n=57) according to body mass index. Genotypes were determined by real-time PCR using TaqMan probes...
December 27, 2017: Gene
https://www.readbyqxmd.com/read/29246245/abo-and-rhesus-blood-group-distribution-and-frequency-among-blood-donors-at-kilimanjaro-christian-medical-center-moshi-tanzania
#10
Ola Jahanpour, Jeremia J Pyuza, Ernest O Ntiyakunze, Alex Mremi, Elichilia R Shao
OBJECTIVE: This study aims to determine the distribution of blood groups and the demographic background of blood donors in a referral hospital in Northern Tanzania. RESULTS: The most common blood group was O (52.3%) and the least common was AB (3.18%). 97.7% of the blood donors were Rh positive and the rest were Rh negative. Most donors were young adults, representing the age group of 19-29. The majority of donors were male (88.1%) and the majority (90.8%) were replacement while the remainder was voluntary donors...
December 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29244085/effects-of-cold-exposure-on-physiology-meat-quality-and-behavior-of-turkey-hens-and-toms-crated-at-transport-density
#11
Z A Henrikson, C J Vermette, K Schwean-Lardner, T G Crowe
The impact of cold exposure while crated at a density characteristic of transport (83 kg/m2) was assessed in 12-wk-old turkey hens and 16-wk-old toms. Turkeys (72 toms, 72 hens) were randomly divided into 3 male and 3 female groups: 2 moderate 20°C groups with either 30% or 80% RH and a cold group exposed to -18°C, with uncontrolled, high RH. Groups of 8 birds (one replicate unit) were observed in a climate-controlled chamber for 8 h prior to slaughter. Core body temperature (CBT), live shrink, heterophil-lymphocyte ratio (HLR), and change in blood glucose levels were assessed; meat quality measures included thigh and breast muscle pH and L*, a*, and b* color values...
December 13, 2017: Poultry Science
https://www.readbyqxmd.com/read/29199733/a-robust-portable-and-backflow-free-micromixing-device-based-on-both-capillary-and-vacuum-driven-flows
#12
Yaguang Zhai, Anyang Wang, Domin Koh, Philip Schneider, Kwang W Oh
In capillary- or vacuum-driven microfluidics, surge backflow events are common when merging or pumping two similar or dissimilar liquids together if a pressure difference exists between them. In this work, a robust, portable micromixing device that is insensitive to backflow was designed, fabricated and characterised. A capillary-driven pressure balancing bypass connected between two inlet ports diminished the initial pressure difference caused by capillarity and gravity present in each liquid at the two inlet ports...
December 4, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/29193618/distribution-of-abo-rh-blood-groups-and-their-association-with-hepatitis-b-virus-infection-in-3-8-million-chinese-adults-a-population-based-cross-sectional-study
#13
Jue Liu, Shikun Zhang, Min Liu, Qiaomei Wang, Haiping Shen, Yiping Zhang
ABO and rhesus (Rh) blood groups play a vital role in blood transfusion safety, clinical practice and are thought to be linked with disease susceptibility. The results from previous studies that focused on the association between blood groups and hepatitis B virus (HBV) infection remain controversial. China has the world's largest burden of HBV infection. We assessed the distribution of ABO/Rh blood groups in Chinese adults and examined the association between these groups and HBV infection. We did a nationwide cross-sectional study using data from a physical check-up program from 31 provinces examined between 2010 and 2012...
November 28, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29193130/evaluation-of-a-lateral-flow-based-technology-card-for-blood-typing-using-a-simplified-protocol-in-a-model-of-extreme-blood-sampling-conditions
#14
Benoît Clavier, Thomas Pouget, Anne Sailliol
BACKGROUND: Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick results. STUDY DESIGN AND METHODS: A simplified protocol was developed for the lateral flow-based device MDmulticard ABO-D-Rh subgroups-K. Its performance was compared to a reference method (PK7300, Beckman Coulter) in native blood samples from donors...
November 29, 2017: Transfusion
https://www.readbyqxmd.com/read/29193104/transfusion-strategy-for-weak-d-type-4-0-based-on-rhd-alleles-and-rh-haplotypes-in-tunisia
#15
Mouna Ouchari, Kshitij Srivastava, Houda Romdhane, Saloua Jemni Yacoub, Willy Albert Flegel
BACKGROUND: With more than 460 RHD alleles, this gene is the most complex and polymorphic among all blood group systems. The Tunisian population has the largest known prevalence of weak D Type 4.0 alleles, occurring in one of 105 RH haplotypes. We aimed to establish a rationale for the transfusion strategy of weak D Type 4.0 in Tunisia. STUDY DESIGN AND METHODS: Donors were randomly screened for the serologic weak D phenotype. The RHD coding sequence and parts of the introns were sequenced...
November 29, 2017: Transfusion
https://www.readbyqxmd.com/read/29172950/the-safety-and-feasibility-of-three-dimensional-visualization-technology-assisted-right-posterior-lobe-allied-with-part-of-v-and-viii-sectionectomy-for-right-hepatic-malignancy-therapy
#16
Min Hu, Haoyu Hu, Wei Cai, Zhikang Mo, Nan Xiang, Jian Yang, Chihua Fang
BACKGROUND: Hepatectomy is the optimal method for liver cancer; the virtual liver resection based on three-dimensional visualization technology (3-DVT) could provide better preoperative strategy for surgeon. We aim to introduce right posterior lobe allied with part of V and VIII sectionectomy assisted by 3-DVT as a promising treatment for massive or multiple right hepatic malignancies to retain maximum residual liver volume on the basis of R0 resection. METHODS: Among 126 consecutive patients who underwent hepatectomy, 9 (7%) underwent right posterior lobe allied with part of V and VIII sectionectomy...
November 27, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29153948/rh-blood-phenotyping-d-e-e-c-c-microarrays-using-multichannel-surface-plasmon-resonance-imaging
#17
Chinnawut Pipatpanukul, Sasaki Takeya, Akira Baba, Ratthasart Amarit, Armote Somboonkaew, Boonsong Sutapun, Pimpun Kitpoka, Mongkol Kunakorn, Toemsak Srikhirin
The application of Surface Plasmon Resonance Imaging (SPRi) for the detection of transmembrane antigen of the Rhesus (Rh) blood group system is demonstrated. Clinically significant Rh blood group system antigens, including D, C, E, c, and e, can be simultaneously identified via solid phase immobilization assay, which offers significant time savings and assay simplification. Red blood cells (RBCs) flowed through the micro-channel, where a suitable condition for Rh blood group detection was an RBC dilution of 1:10 with a stop-flow condition...
November 2, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29119571/targeted-exome-sequencing-defines-novel-and-rare-variants-in-complex-blood-group-serology-cases-for-a-red-blood-cell-reference-laboratory-setting
#18
Elizna M Schoeman, Eileen V Roulis, Yew-Wah Liew, Jacqueline R Martin, Tanya Powley, Brett Wilson, Glenda M Millard, Eunike C McGowan, Genghis H Lopez, Helen O'Brien, Jennifer A Condon, Robert L Flower, Catherine A Hyland
BACKGROUND: We previously demonstrated that targeted exome sequencing accurately defined blood group genotypes for reference panel samples characterized by serology and single-nucleotide polymorphism (SNP) genotyping. Here we investigate the application of this approach to resolve problematic serology and SNP-typing cases. STUDY DESIGN AND METHODS: The TruSight One sequencing panel and MiSeq platform was used for sequencing. CLC Genomics Workbench software was used for data analysis of the blood group genes implicated in the serology and SNP-typing problem...
November 8, 2017: Transfusion
https://www.readbyqxmd.com/read/29076664/routine-preoperative-blood-group-and-save-testing-is-unnecessary-for-elective-laparoscopic-cholecystectomy
#19
Ashutosh Tandon, Kashif Shahzad, Quentin Nunes, Milind Shrotri, Raimundas Lunevicius
Background: Although the practice of preoperative testing of ABO group and Rh (D) type for elective cholecystectomy has deep historical roots, it is not evidence-based. We aimed to assess the preoperative blood group and save testing practice for a cohort of patients subjected to elective laparoscopic cholecystectomy for symptomatic cholecystolithiasis between January 2010 and October 2014. Methods: National Health Service (NHS) hospital based, surgical procedure-specific, retrospective study was conducted...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29072060/risk-factors-for-hydatidiform-mole-is-husband%C3%A2-s-job-a-major-risk-factor
#20
Hourieh Shamshiri Milani, Morteza Abdollahi, Sara Torbati, Taha Asbaghi, Eznollah Azargashb
Background: The hydatidiform mole (HM) is a precancerous placenta considered as a gestational trophoblastic disease (GTD). It may convert to more invasive forms of gestational trophoblastic neoplasia (GTN), endangering women’s health by more severe complications. Most GTN cases originate from HM, which is associated with uterine bleeding, preeclampsia and thyroid problems. Its etiology has not been adequately explored, but some risk factors have been reported. The aim of the present study was to assess any relationships between molar pregnancy and factors including mothers’ and husbands’ occupations...
October 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
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