keyword
MENU ▼
Read by QxMD icon Read
search

ya

keyword
https://www.readbyqxmd.com/read/29454274/a-multifaceted-coating-on-titanium-dictates-osteoimmunomodulation-and-osteo-angio-genesis-towards-ameliorative-osseointegration
#1
Long Bai, Zhibin Du, Jingjing Du, Wei Yao, Jiaming Zhang, Zeming Weng, Si Liu, Ya Zhao, Yanlian Liu, Xiangyu Zhang, Xiaobo Huang, Xiaohong Yao, Ross Crawford, Ruiqiang Hang, Di Huang, Bin Tang, Yin Xiao
A multifaceted coating for hard tissue implants, with favorable osteogenesis, angiogenesis, and osteoimmunomodulation abilities, would be of great value since it could improve osseointegration and alleviate prosthesis loosening. However, to date there are few coatings that fully satisfy these criteria. Herein we describe a microporous TiO 2 coating decorated with hydroxyapatite (HA) nanoparticles that is generated by micro-arc oxidation of pure titanium (Ti) and followed annealing. By altering the annealing temperature, it is possible to simultaneously tune the coating's physical (morphology and wettability) and chemical (composites and crystallinity) properties...
February 6, 2018: Biomaterials
https://www.readbyqxmd.com/read/29453968/lipoprotein-lipase-biosynthesis-regulatory-factors-and-its-role-in-atherosclerosis-and-other-diseases
#2
REVIEW
Ping-Ping He, Ting Jiang, Xin-Ping OuYang, Ya-Qin Liang, Jie-Qiong Zou, Yan Wang, Qian-Qian Shen, Li Liao, Xi-Long Zheng
Lipoprotein lipase (LPL) is a rate-limiting enzyme that catalyzes hydrolysis of the triglyceride (TG) core of circulating TG-rich lipoproteins including chylomicrons (CM), low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL). A variety of parenchymal cells can synthesize and secrete LPL. Recent studies have demonstrated that complicated processes are involved in LPL biosynthesis, secretion and transport. The enzyme activity of LPL is regulated by many factors, such as apolipoproteins, angiopoietins, hormones and miRNAs...
February 14, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29453688/rapid-optimization-of-spore-production-from-bacillus-amyloliquefaciens-in-submerged-cultures-based-on-dipicolinic-acid-fluorimetry-assay
#3
Hang Ren, Ya-Ting Su, Xiao-Hua Guo
Some optimization techniques have been widely applied for spore fermentation based on the plate counting. This study optimized the culture medium for the spore production of Bacillus amyloliquefaciens BS-20 and investigated the feasibility of using a dipicolonic acid (DPA) fluorimetry assay as a simpler alternative to plate counting for evaluating spore yields. Through the single-factor experiment, the metal ions and agro-industrial raw materials that significantly enhanced spore production were determined...
February 16, 2018: AMB Express
https://www.readbyqxmd.com/read/29453660/verification-of-candidate-microrna-markers-for-parathyroid-carcinoma
#4
Ya Hu, Xiang Zhang, Ming Cui, Zhe Su, Mengyi Wang, Quan Liao, Yupei Zhao
PURPOSE: Parathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited number of samples. The aim of the present study was to verify a group of miRNA markers in a new series of samples to explore their potential significance in PCa diagnosis. METHODS: A total of 58 tissue samples, including 17 PCa lesions and 41 sporadic parathyroid adenomas (PAds), were obtained from 56 primary hyperparathyroidism (pHPT) patients...
February 16, 2018: Endocrine
https://www.readbyqxmd.com/read/29453559/regulation-of-h-pyrophosphatase-by-14-3-3-proteins-from-arabidopsis-thaliana
#5
Yu-Di Hsu, Yu-Fen Huang, Yih-Jiuan Pan, Li-Kun Huang, Ya-Yun Liao, Wei-Hua Lin, Tzu-Yin Liu, Ching-Hung Lee, Rong-Long Pan
Plant vacuolar H + -transporting inorganic pyrophosphatase (V-PPase; EC 3.6.1.1) is a crucial enzyme that exists on the tonoplast to maintain pH homeostasis across the vacuolar membrane. This enzyme generates proton gradient between cytosol and vacuolar lumen by hydrolysis of a metabolic byproduct, pyrophosphate (PP i ). The regulation of V-PPase at protein level has drawn attentions of many workers for decades, but its mechanism is still unclear. In this work, we show that AVP1, the V-PPase from Arabidopsis thaliana, is a target protein for regulatory 14-3-3 proteins at the vacuolar membrane, and all twelve 14-3-3 isoforms were analyzed for their association with AVP1...
February 16, 2018: Journal of Membrane Biology
https://www.readbyqxmd.com/read/29453048/a-system-composed-of-a-biofilm-electrode-reactor-and-a-microbial-fuel-cell-constructed-wetland-exhibited-efficient-sulfamethoxazole-removal-but-induced-sul-genes
#6
Shuai Zhang, Hai-Liang Song, Xiao-Li Yang, Hua Li, Ya-Wen Wang
The aim of this work was to study sulfamethoxazole (SMX) removal efficiency and fate of corresponding sul genes in a stacked microbial fuel cell-constructed wetland coupled biofilm electrode reactor system (MFC-CW-BER). Findings showed that two stacked MFC-CWs could provide a relatively stable electricity supply to support the biofilm for SMX removal. Excellent SMX removal (>99.29%) was obtained in the BER-MFC-CW. Compared with the 2000 µg L -1 SMX influent, the relative abundance of the sul genes in biofilm media and effluent was enhanced with continuously high concentrations of SMX (4000 μg L -1 )...
February 7, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29452165/the-beneficial-role-of-early-exercise-training-following-stroke-and-possible-mechanisms
#7
REVIEW
Ying Xing, Si-Dong Yang, Fang Dong, Man-Man Wang, Ya-Shuo Feng, Feng Zhang
Exercise training is a regular therapy for stroke patients in clinic. However, whether the early exercise is beneficial for stroke patients is still controversial. The review was performed in databases of OVID, PUBMED, and ISI Web of Science, from respective inception to December 2017. In this review, we summarize the effect of different exercise intensity, initiation time, and style on ischemic stroke. Moreover, the possible mechanism is also discussed. The conclusion is that the voluntary exercise is better in promoting the functional recovery following stroke compared to forced exercise; too early initiated exercise might play a harmful role following stroke, while early initiated exercise might exert benefits after stroke; mild and moderate intensity exercise training could generate better neuroprotection in comparison with high intensity exercise training; early excise training could regulate the process of brain edema, cell apoptosis, oxidative damage, stem cells and other mechanisms in order to exert neuroprotection for brain...
February 13, 2018: Life Sciences
https://www.readbyqxmd.com/read/29451186/-lactobacillus-acidophilus-and-bifidobacterium-longum-supernatants-upregulate-the-serotonin-transporter-expression-in-intestinal-epithelial-cells
#8
Ya-Nan Cao, Li-Juan Feng, Bang-Mao Wang, Kui Jiang, Shu Li, Xin Xu, Wei-Qiang Wang, Jing-Wen Zhao, Yu-Ming Wang
Background/Aims: Probiotics play a role in relieving irritable bowel syndrome (IBS); however, the underlying mechanism is yet unclear. The aim of the study was to investigate the effects of the supernatants of Lactobacillus acidophilus and Bifidobacterium longum on the expression of serotonin transporter (SERT) messenger ribonucleic acid (mRNA) and protein. Materials and Methods: HT-29 and Caco-2 cells were treated with different concentrations of L. acidophilus and B...
January 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29451146/safety-and-efficiency-of-trabectome-mediated-trabecular-meshwork-ablation-for-chinese-glaucoma-patients-a-two-year-retrospective-multicentre-study
#9
Ya-Long Dang, Yu-Jie Cen, Ying Hong, Ping Huang, Ning-Li Wang, Chao Wang, Chun Zhang
Background: The aim of the study was to evaluate the long-term safety and efficacy of the Trabectome for Chinese glaucoma patients. Methods: This was a multicenter, retrospective, observational study. Glaucoma patients, except those with neovascular glaucoma, with/without a visually significant cataract were enrolled. The patients received Trabectome or a combined surgery with phacoemulsification and intraocular lens implantation. The primary outcome evaluation was a reduction in intraocular pressure (IOP), and the secondary outcomes were a reduction in glaucoma medication, the 2-year success percentages, and complications...
February 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29451143/familial-nonmedullary-thyroid-carcinoma-a-retrospective-analysis-of-117-families
#10
Ya-Bing Zhang, Xiao-Xin Wang, Xi-Wei Zhang, Zheng-Jiang Li, Jie Liu, Zhen-Gang Xu, Ping-Zhang Tang
Background: The first and most important step in characterizing familial nonmedullary thyroid carcinoma (NMTC) is to distinguish the true familial patients, which is the prerequisite for all accurate analyses. This study aimed to investigate whether patients from families with ≥3 first-degree relatives affected with NMTC have different characteristics than patients from families with only two affected members, and to compare these patients with those with sporadic disease. Methods: We analyzed the clinicopathological features and prognosis of 209 familial and 1120 sporadic cases of NMTC...
February 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29451138/detection-of-repair-of-the-zone-of-calcified-cartilage-with-osteoarthritis-through-mesenchymal-stem-cells-by-ultrashort-echo-time-magnetic-resonance-imaging
#11
REVIEW
Quan Zhou, Shao-Lin Li, Ya-Jun Ma, Vicki de Tal, Wei Li, Ying-Hua Zhao
Objective: Currently, magnetic resonance imaging (MRI) is the most commonly used imaging modality for observing the growth and development of mesenchymal stem cells (MSCs) after in vivo transplantation to treat osteoarthritis (OA). However, it is a challenge to accurately monitor the treatment effects of MSCs in the zone of calcified cartilage (ZCC) with OA. This is especially true in the physiological and biochemical views that are not accurately detected by MRI contrast agents. In contrast, ultrashort time echo (UTE) MRI has been shown to be sensitive to the presence of the ZCC, creating the potential for more effectively observing the repair of the ZCC in OA by MSCs...
February 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29450425/in-situ-growth-of-all-inorganic-perovskite-nanocrystals-on-black-phosphorus-nanosheets
#12
Hao Huang, Jia Li, Ya Yi, Jiahong Wang, Yihong Kang, Paul K Chu, H C Ong, Xue-Feng Yu
This communication describes a novel low-dimensional nanohybrid structure consisting of all-inorganic perovskite nanocrystals (NCs) growing in situ on two-dimensional (2D) black phosphorus (BP) nanosheets. Such a nanohybrid structure promises synergetic properties by combining the respective strengths of perovskite materials and BP, which opens new opportunities for next-generation optoelectronic devices.
February 16, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29449876/authenticity-analyses-of-rhizoma-paridis-using-barcoding-coupled-with-high-resolution-melting-bar-hrm-analysis-to-control-its-quality-for-medicinal-plant-product
#13
Bao-Zhong Duan, Ya-Ping Wang, Hai-Lan Fang, Chao Xiong, Xi-Wen Li, Ping Wang, Shi-Lin Chen
Background: Rhizoma Paridis (Chonglou) is a commonly used and precious traditional Chinese medicine. Paris polyphylla Smith var. yunnanensis (Franch.) Hand. -Mazz. and Paris polyphylla Smith var . chinensis (Franch.) Hara are the two main sources of Chonglou under the monograph of Rhizoma Paridis in Chinese Pharmacopoeia. In the local marketplace, however, this medicine is prone to be accidentally contaminated, deliberately substituted or admixed with other species that are similar to Rhizoma Paridis in shape and color...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29449644/inhibition-of-the-jnk-mapk-signaling-pathway-by-myogenesis-associated-mirnas-is-required-for-skeletal-muscle-development
#14
Shu-Juan Xie, Jun-Hao Li, Hua-Feng Chen, Ye-Ya Tan, Shu-Rong Liu, Yin Zhang, Hui Xu, Jian-Hua Yang, Shun Liu, Ling-Ling Zheng, Mian-Bo Huang, Yan-Hua Guo, Qi Zhang, Hui Zhou, Liang-Hu Qu
Skeletal muscle differentiation is controlled by multiple cell signaling pathways, however, the JNK/MAPK signaling pathway dominating this process has not been fully elucidated. Here, we report that the JNK/MAPK pathway was significantly downregulated in the late stages of myogenesis, and in contrast to P38/MAPK pathway, it negatively regulated skeletal muscle differentiation. Based on the PAR-CLIP-seq analysis, we identified six elevated miRNAs (miR-1a-3p, miR-133a-3p, miR-133b-3p, miR-206-3p, miR-128-3p, miR-351-5p), namely myogenesis-associated miRNAs (mamiRs), negatively controlled the JNK/MAPK pathway by repressing multiple factors for the phosphorylation of the JNK/MAPK pathway, including MEKK1, MEKK2, MKK7, and c-Jun but not JNK protein itself, and as a result, expression of transcriptional factor MyoD and mamiRs were further promoted...
February 15, 2018: Cell Death and Differentiation
https://www.readbyqxmd.com/read/29449539/g9a-promotes-gastric-cancer-metastasis-by-upregulating-itgb3-in-a-set-domain-independent-manner
#15
Lei Hu, Ming-de Zang, He-Xiao Wang, Bao-Gui Zhang, Zhen-Qiang Wang, Zhi-Yuan Fan, Huo Wu, Jian-Fang Li, Li-Ping Su, Min Yan, Zhi-Qiang Zhu, Qiu-Meng Yang, Qiang Huang, Bing-Ya Liu, Zheng-Gang Zhu
Tumor metastasis is the leading cause of death in patients with advanced gastric cancer (GC). Limited therapeutic regimens are available for this condition, which is associated with a poor prognosis, and the mechanisms underlying tumor metastasis remain unclear. In the present study, increased histone methyltransferase G9A expression in GC tissues correlated with advanced stage and shorter overall survival, and in vitro and in vivo experiments revealed that G9A promoted tumor invasion and metastasis. Moreover, we observed that Reg IV induced G9A via the p-ERK/p-SP1 pathway...
February 15, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29449536/impaired-autophagic-flux-is-associated-with-the-severity-of-trauma-and-the-role-of-a-2a-r-in-brain-cells-after-traumatic-brain-injury
#16
Xu-Jia Zeng, Ping Li, Ya-Lei Ning, Yan Zhao, Yan Peng, Nan Yang, Zi-Ai Zhao, Jiang-Fan Chen, Yuan-Guo Zhou
Recent studies have shown that after traumatic brain injury (TBI), the number of autophagosomes is markedly increased in brain cells surrounding the wound; however, whether autophagy is enhanced or suppressed by TBI remains controversial. In our study, we used a controlled cortical impact system to establish models of mild, moderate and severe TBI. In the mild TBI model, the levels of autophagy-related protein 6 (Beclin1) and autophagy-related protein 12 (ATG12)-autophagy-related protein 5 (ATG5) conjugates were increased, indicating the enhanced initiation of autophagy...
February 14, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29449183/altered-resting-state-voxel-level-whole-brain-functional-connectivity-in-depressed-parkinson-s-disease
#17
Hansheng Wang, Huiyue Chen, Jiahui Wu, Li Tao, Ya Pang, Min Gu, Fajin Lv, Tianyou Luo, Oumei Cheng, Ke Sheng, Jin Luo, Yida Hu, Weidong Fang
BACKGROUND: Depression is one of the most common non-motor symptoms in Parkinson's disease (PD), but its pathogenesis is still not very clear. Recently, degree centrality, a voxel-level whole-brain functional connectivity (FC) analysis of resting-state functional magnetic resonance imaging, has provided the most promising way to explore the neural network mechanisms underlying depressed PD. METHODS: Degree centrality, voxel-wise image and clinical symptoms correlation and secondary seed-based FC analyses were performed in twenty-seven drug-naïve, early stage depressed PD patients, 27 non-depressed PD patients and 27 healthy controls (HCs) to reveal voxel-level whole-brain FC changes in depressed PD...
February 9, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29449087/two-dimensional-correlation-spectroscopic-studies-on-coordination-between-organic-ligands-and-ni-2-ions
#18
Ya-Nan Bao, Yi-Wei Zeng, Ran Guo, Mesude Ablikim, Hai-Fang Shi, Li-Min Yang, Zhan-Lan Yang, Yi-Zhuang Xu, Isao Noda, Jin-Guang Wu
3 A 2g → 3 T 1g (P) transition band of Ni 2+ is used to probe the coordination of Ni 2+ . Two-dimensional asynchronous spectra (2DCOS) are generated using the Double Asynchronous Orthogonal Sample Design (DAOSD), Asynchronous Spectrum with Auxiliary Peaks (ASAP) and Two-Trace Two-Dimensional (2T2D) approaches. Cross peaks relevant to the 3 A 2g → 3 T 1g (P) transition band of Ni 2+ are utilized to probe coordination between Ni 2+ and various ligands. We studied the spectral behavior of the 3 A 2g → 3 T 1g (P) transition band when Ni 2+ is coordinated with ethylenediaminetetraacetic acid disodium salt (EDTA)...
December 7, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29449021/effect-of-matrix-metalloproteinase-8-inhibitor-on-resin-dentin-bonds
#19
Qianmin Ou, Ya Hu, Siqi Yao, Yan Wang, Xuefeng Lin
OBJECTIVES: This study investigated the effect of matrix metalloproteinase 8 (MMP-8) on resin-dentin bonds, assessed the mechanical properties of the interfaces over time, and discussed the potential application of MMP-8 inhibitor I (MMP8-I) as a specific MMP-8 inhibitor to be incorporated into dental adhesives. METHODS: The activation and inhibition of MMP-8 was detected by colorimetric assay. After 1 day, 6 months and 1 year of storage of Control, MMP8-I, and chlorhexidine (CHX) groups, the microtensile bond strengths (μTBS) were used to evaluate the bond strength and failure mode distributions, and nanoleakage analysis was used to evaluate the minor scattered silver particles...
February 12, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29448753/tailored-pt-tio%C3%A2-photocatalyst-with-controllable-phase-prepared-via-a-modified-sol-gel-process-for-dye-degradation
#20
Bing-Shun Huang, En-Chin Su, Yun-Ya Huang, Hui-Hsin Tseng
Pt/TiO2 photocatalysts with controllable phase were successfully prepared by controlling the hydrolysis pH values during the sol-gel process followed by Pt photodeposition. The effect of different phases of TiO2 coated with Pt on the catalytic properties and the photocatalytic activities were also investigated. The characterization results of the synthesis of TiO2 under neutral/alkaline and acidic conditions during the hydrolysis step revealed the facile formation of the anatase phase and the brookite/rutile phase, respectively...
March 1, 2018: Journal of Nanoscience and Nanotechnology
keyword
keyword
69826
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"