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https://www.readbyqxmd.com/read/27915477/treadmill-exercise-improves-memory-function-depending-on-circadian-rhythm-changes-in-mice
#1
Dong Sup Hwang, Hyo Bum Kwak, Il Gyu Ko, Sung Eun Kim, Jun Jang Jin, Eun Sang Ji, Hyun Hee Choi, Oh Young Kwon
PURPOSE: Exercise enhances memory function by increasing neurogenesis in the hippocampus, and circadian rhythms modulate synaptic plasticity in the hippocampus. The circadian rhythm-dependent effects of treadmill exercise on memory function in relation with neurogenesis were investigated using mice. METHODS: The step-down avoidance test was used to evaluate short-term memory, the 8-arm maze test was used to test spatial learning ability, and 5-bromo-2'-deoxyuridine immunofluorescence was used to assess neurogenesis...
November 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27915207/fixed-distance-walk-tests-at-comfortable-and-fast-speed-potential-tools-for-the-functional-assessment-of-coronary-patients
#2
Marie-Doriane Morard, Delphine Besson, Davy Laroche, Alexandre Naaïm, Vincent Gremeaux, Jean-Marie Casillas
OBJECTIVES: There is ambiguity concerning the walk tests available for functional assessment of coronary patients, particularly for the walking speed. This study explores the psychometric properties of two walking tests, based on fixed-distance tests, at comfortable and fast velocity, in stabilized patients at the end of a cardiac rehabilitation program. METHODS: At a three-day interval 58 coronary patients (mean age of 64.85±6.03 years, 50 men) performed three walk tests, the first two at a comfortable speed in a random order (6-minute walk test - 6MWT - and 400-metre comfortable walk test - 400mCWT) and the third at a brisk speed (200-metre fast walk test - 200mFWT)...
November 30, 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27914305/effectiveness-of-a-cross-circuit-exercise-training-program-in-improving-the-fitness-of-overweight-or-obese-adolescents-with-intellectual-disability-enrolled-in-special-education-schools
#3
Wen-Lan Wu, Yu-Fen Yang, I-Hua Chu, Hsiu-Tao Hsu, Feng-Hua Tsai, Jing-Min Liang
This study assessed the effects of a cross-circuit training intervention program on the body composition, cardiorespiratory fitness, balance, and muscular strength endurance of overweight or obese students with intellectual disability. A total of 43 students with intellectual disability (aged 13-19 years) were enrolled in this program; 28 overweight/obese students were assigned to either an obesity-control group (n=14) or obesity-exercise group (n=14), and those with normal weight were assigned to a normal weight group (n=15)...
November 30, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27913834/key-role-of-pacing-site-as-determinant-factor-of-exercise-testing-performance-in-pediatric-patients-with-chronic-ventricular-pacing
#4
Michel Cabrera Ortega, Hiram Tápanes Duamy, Dunia B Benítez Ramos
Chronic right ventricular (RV) apical pacing has been associated with deterioration of functional capacity and chronotropic incompetence during exercise testing in children. The effects of alternative pacing site on exercise performance in pediatric population remain unknown. We evaluated the influence of ventricular pacing site on exercise capacity in pediatric patients with complete congenital atrioventricular block requiring permanent pacemaker therapy. Sixty-four children paced from RV apex (n = 26), RV midseptum (n = 15) and left ventricular (LV) apex (n = 23) were studied cross-sectionally...
December 2, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27909228/divergent-outcomes-of-fructose-consumption-on-exercise-capacity-of-rats-friend-or-foe
#5
Angela Sun, An Huang, Elizabeth Kertowidjojo, Su Song, Thomas H Hintze, Dong Sun
To test the hypothesis that high fructose (HF) consumption divergently affects exercise capability, as a function of feeding duration, rats were fed a normal (as control) or a normal caloric diet with HF for 3, 6, 10 and 30 days respectively, and run on a treadmill. Results show that running distance and work were significantly increased, associated with greater exercise oxygen consumption in rats fed HF for 3 (HF-3D) and 6 days, but were decreased in rats fed HF for 30 days (HF-30D) compared to their respective control rats...
December 1, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27909152/involvement-of-mesolimbic-dopaminergic-network-in-neuropathic-pain-relief-by-treadmill-exercise-a-study-for-specific-neural-control-with-gi-dreadd-in-mice
#6
Kenta Wakaizumi, Takashige Kondo, Yusuke Hamada, Michiko Narita, Rui Kawabe, Hiroki Narita, Moe Watanabe, Shigeki Kato, Emiko Senba, Kazuto Kobayashi, Naoko Kuzumaki, Akihiro Yamanaka, Hiroshi Morisaki, Minoru Narita
BACKGROUND: Exercise alleviates pain and it is a central component of treatment strategy for chronic pain in clinical setting. However, little is known about mechanism of this exercise-induced hypoalgesia. The mesolimbic dopaminergic network plays a role in positive emotions to rewards including motivation and pleasure. Pain negatively modulates these emotions, but appropriate exercise is considered to activate the dopaminergic network. We investigated possible involvement of this network as a mechanism of exercise-induced hypoalgesia...
2016: Molecular Pain
https://www.readbyqxmd.com/read/27908464/effects-of-different-duration-exercise-programs-in-children-with-severe-burns
#7
Robert P Clayton, Paul Wurzer, Clark R Andersen, Ronald P Mlcak, David N Herndon, Oscar E Suman
INTRODUCTION: Burns lead to persistent and detrimental muscle breakdown and weakness. Standard treatment at our institution includes a voluntary 12-week rehabilitative exercise program to limit and reverse the effects of increased muscle catabolism. In the present work, we investigated if different durations of exercise, 6 or 12 weeks, produce comparable improvements in muscle strength, body composition, and cardiopulmonary fitness. METHODS: We prospectively enrolled and randomized patients with ≥30% total body surface area (TBSA) burned to receive 6 or 12 weeks of exercise rehabilitation...
November 28, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27904422/the-effect-of-preventive-therapeutic-and-protective-exercises-on-hippocampal-memory-mediators-in-stressed-rats
#8
Maryam Radahmadi, Nasrin Hosseini, Hojjatallah Alaei, Mohammad Reza Sharifi
BACKGROUND: Exercise plays a significant role in learning and memory. The present study focuses on the hippocampal corticosterone (CORT), interleukin-1 beta (IL-1β), glucose, and brain-derived neurotrophic factor (BDNF) levels in preventive, therapeutic, and protective exercises in stressful conditions. METHODS: Forty male rats were randomly divided into four groups: the control group and the preventive, therapeutic, and protective exercise groups. The treadmill running was applied at a speed of 20-21m/min and a chronic stress of 6 hours/day for 21 days...
September 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27904240/effectiveness-of-exercise-on-functional-mobility-in-adults-with-cerebral-palsy-a-systematic-review
#9
Hillary Lawrence, Sara Hills, Nicole Kline, Kyra Weems, Antonette Doty
Purpose: We identified evidence evaluating the effect of exercise on functional mobility in adults (aged 18 y or older) with cerebral palsy (CP). Method: An exhaustive search was conducted using the electronic databases PubMed, MEDLINE, CINAHL, PsycINFO, SPORTDiscus, and Cochrane Database of Systematic Reviews from the earliest available evidence (1975) to the present (January 2016) for studies whose participants were ambulatory adults with CP receiving conservative treatment to address functional mobility limitations...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27903538/right-ventricular-dysfunction-impairs-effort-tolerance-independent-of-left-ventricular-function-among-patients-undergoing-exercise-stress-myocardial-perfusion-imaging
#10
Jiwon Kim, Antonino Di Franco, Tania Seoane, Aparna Srinivasan, Polydoros N Kampaktsis, Alexi Geevarghese, Samantha R Goldburg, Saadat A Khan, Massimiliano Szulc, Mark B Ratcliffe, Robert A Levine, Ashley E Morgan, Pooja Maddula, Meenakshi Rozenstrauch, Tara Shah, Richard B Devereux, Jonathan W Weinsaft
BACKGROUND: Right ventricular (RV) and left ventricular (LV) function are closely linked due to a variety of factors, including common coronary blood supply. Altered LV perfusion holds the potential to affect the RV, but links between LV ischemia and RV performance, and independent impact of RV dysfunction on effort tolerance, are unknown. METHODS AND RESULTS: The population comprised 2051 patients who underwent exercise stress myocardial perfusion imaging and echo (5...
November 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27901338/determinant-factors-of-peak-treadmill-speed-in-physically-active-men
#11
Leonardo Alves Pasqua, Mayara V Damasceno, Salomão Bueno, Alessandro M Zagatto, Gustavo G DE Araújo, Adriano E Lima-Silva, Rômulo Bertuzzi
BACKGROUND: The aim of the present study was to determine whether physiological factors and maximal dynamic strength are able to determine the peak treadmill speed (PTS) in physically active individuals. METHODS: One hundred and fifty physically active healthy males voluntarily visit the laboratory on three separate occasions and underwent the following activities: first visit: IPAQ (short version), anthropometric measurements, and a maximal incremental test performed for physiological variables (maximal oxygen uptake ( ) and respiratory compensation point (RCP); second visit: constant speed test for running economy (RE) measurement, and familiarization with the maximum dynamic strength (1RM) test in the leg press exercise; third visit: 1RM test...
November 30, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27901314/effects-of-hypoxia-and-hypercapnic-hypoxia-on-oxygen-transport-and-acid-base-status-in-the-atlantic-blue-crab-callinectes-sapidus-during-exercise
#12
Mark P Lehtonen, Louis E Burnett
The responses of estuarine invertebrates to hypoxic conditions are well established. However, many studies have investigated hypoxia as an isolated condition despite its frequent co-occurrence with hypercapnia (elevated CO2 ). Although many studies suggest deleterious effects, hypercapnia has been observed to improve blue crab walking performance in hypoxia. To investigate the physiological effects of combined hypercapnic hypoxia, we measured Po2 , pH, [l-lactate], Pco2 , and total O2 in pre- and postbranchial hemolymph sampled from blue crabs during walking exercise...
November 30, 2016: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
https://www.readbyqxmd.com/read/27900294/efficacy-of-autologous-leukocyte-reduced-platelet-rich-plasma-therapy-for-patellar-tendinopathy-in-a-rat-treadmill-model
#13
Mamoru Yoshida, Hiroki Funasaki, Keishi Marumo
BACKGROUND: An autologous platelet-rich plasma (PRP) therapy has currently been applied for the tendinopathy; however, its efficacy and an optimal platelets concentration in PRP were uncertain. We analyzed them in an animal model prepared using a repetitive running exercise. METHODS: We made the tendinopathy rat model of patellar tendon using a rodent treadmill machine. Rats with tendinopathy were injected with leukocyte-reduced PRP at the platelets concentration of 1...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27900177/high-intensity-interval-training-to-improve-fitness-in-children-with-cerebral-palsy
#14
Reidun Lauglo, Torstein Vik, Torarin Lamvik, Dorthe Stensvold, Ane-Kristine Finbråten, Trine Moholdt
AIM: To evaluate effects of high-intensity interval training (HIT) on aerobic exercise capacity, quality of life, and body composition in children with cerebral palsy (CP). METHODS: This was a baseline control trial. Children with CP, Gross Motor Function Classification System (GMFCS) levels I-IV, and age 10-17 years were included. The primary outcome, peak, and submaximum oxygen uptake (VO2peak, VO2submax) were measured at enrolment to the study (T0), after a pretraining period (T1), and after HIT (T2)...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27892886/safety-profile-and-utility-of-treadmill-exercise-in-patients-with-high-gradient-hypertrophic-cardiomyopathy
#15
Lars Lindholm Sorensen, Hsin-Yueh Liang, Aurelio Pinheiro, Alex Hilser, Veronica Dimaano, Niels Thue Olsen, Thomas Fritz Hansen, Peter Sogaard, Alexandra Nowbar, Chiara Pisanello, Iraklis Pozios, Susan Phillip, Xun Zhou, Roselle Abraham, Theodore P Abraham
: Exercise echocardiography in the evaluation of hypertrophic cardiomyopathy (HCM) provides valuable information for risk stratification, selection of optimal treatment, and prognostication. However, HCM patients with left ventricular outflow tract gradients ≥30mm Hg are often excluded from exercise testing because of safety considerations. We examined the safety and utility of exercise testing in patients with high-gradient HCM. METHODS: We evaluated clinical characteristics, hemodynamics, and imaging variables in 499 consecutive patients with HCM who performed 959 exercise tests...
October 20, 2016: American Heart Journal
https://www.readbyqxmd.com/read/27889837/exercise-training-effects-on-memory-and-hippocampal-viscoelasticity-in-multiple-sclerosis-a-novel-application-of-magnetic-resonance-elastography
#16
Brian M Sandroff, Curtis L Johnson, Robert W Motl
INTRODUCTION: Cognitive impairment is common and debilitating among persons with multiple sclerosis (MS) and might be managed with exercise training. However, the effects of exercise training on viscoelastic brain properties in this population are unknown. The present pilot study adopted a single-blind randomized controlled trial (RCT) design and is the first to examine the effect of an aerobic exercise training intervention on learning and memory and hippocampal viscoelasticity using magnetic resonance elastography (MRE) in persons with MS...
November 26, 2016: Neuroradiology
https://www.readbyqxmd.com/read/27889467/treadmill-exercise-decreases-amyloid-%C3%AE-burden-possibly-via-activation-of-sirt-1-signaling-in-a-mouse-model-of-alzheimer-s-disease
#17
Jung-Hoon Koo, Eun-Bum Kang, Yoo-Sung Oh, Dae-Seung Yang, Joon-Yong Cho
Accumulation of amyloid-β (Aβ) correlates significantly with progressive cognitive deficits, a main symptom of Alzheimer's disease (AD). Although treadmill exercise reduces Aβ levels, the molecular mechanisms underlying the effects are not fully understood. We hypothesize that treadmill exercise decreases Aβ production and alleviates cognitive deficits by activating the non-amyloidogenic pathway via SIRT-1 signaling. Treadmill exercise improved cognitive deficits and alleviated neurotoxicity. Most importantly, treadmill exercise increased SIRT-1 level, which subsequently resulted in increased ADAM-10 level by down-regulation of ROCK-1 and upregulation of RARβ, ultimately facilitating the non-amyloidogenic pathway...
November 23, 2016: Experimental Neurology
https://www.readbyqxmd.com/read/27884590/physical-activity-induced-protection-against-breast-cancer-risk-associated-with-delayed-parity
#18
Kathleen M Sturgeon, Aaron Schweitzer, John J Leonard, Deirdre K Tobias, Ying Liu, Elizabeth Cespedes Feliciano, Vasanti S Malik, Amit Joshi, Bernard Rosner, Bart C De Jonghe
Epidemiological evidence indicates that physical activity between menarche and first pregnancy is associated with a lower risk of breast cancer among women with at least 20years between these reproductive events. The mechanism by which physical activity during this interval confers protection is unknown. This study used a novel animal model to assess potentially protective effects of physical activity on tumor development in delayed parity. Thirty-six female Sprague Dawley rats received an i.p. injection of 50mg/kg N-methyl-N-nitrosourea (MNU) at 5weeks of age...
November 21, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/27884511/effects-of-previous-physical-training-on-adriamycin-nephropathy-and-its-relationship-with-endothelial-lesions-and-angiogenesis-in-the-renal-cortex
#19
Camila M Faleiros, Heloisa Francescato, Marcelo Papoti, Lucas Chaves, Cleonice Silva, Roberto Costa, Terezila Machado Coimbra
AIMS: Adriamycin (ADR)-induced nephropathy is one of the most experimental models used in progressive kidney disease. A single dose of this drug induces a progressive and irreversible proteinuria that progresses to focal segmental glomerulosclerosis and tubulointerstitial lesions. Regular physical activity has been considered as a therapeutic intervention in several diseases. This study evaluated the influence of previous physical training in renal damage induced by ADR and the role of endothelial lesions and angiogenesis in this process...
November 21, 2016: Life Sciences
https://www.readbyqxmd.com/read/27882731/reproducibility-of-corrected-qt-interval-in-pediatric-genotyped-long-qt-syndrome
#20
Yoshiharu Ogawa, Toshikatsu Tanaka, Sachiko Kido
Reproducibility of corrected QT interval (QTc), especially QTc after exercise, has not been thoroughly investigated. We reviewed charts of pediatric patients who underwent treadmill-exercise stress testing without medication multiple times within 1 year. In patients with long-QT syndrome (LQTS; n = 22), the discrepancy in QTc between two treadmill exercise stress tests using Fridericia's formula was 14 ± 12 ms at rest, 13 ± 12 ms 4 min after exercise, with a maximum of 14 ± 12 ms after exercise. There was no statistically significant difference in QTc between the two tests...
November 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
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