keyword
MENU ▼
Read by QxMD icon Read
search

ubiquitation

keyword
https://www.readbyqxmd.com/read/27926882/effect-of-reduced-humic-acid-on-the-transport-of-ferrihydrite-nanoparticles-under-anoxic-conditions
#1
Peng Liao, Wenlu Li, Dengjun Wang, Yi Jiang, Chao Pan, John D Fortner, Songhu Yuan
Humic acid (HA) occurs ubiquitously in the subsurface environments and is well-known to play a critical role in the fate and transport of ferrihydrite nanoparticles (NPs) and NPs-associated contaminants. Under anoxic conditions, HA can readily be reduced by microorganisms or geochemical reducing species, and the mechanisms and kinetics of ferrihydrite reduction by reduced HA (HAred) are well-documented; however, the role of these redox reactions on the transport of ferrihydrite NPs is largely underestimated...
December 1, 2016: Water Research
https://www.readbyqxmd.com/read/27926825/mycobacterium-malmesburyense-sp-nov-a-novel-non-tuberculous-mycobacterium-species-revealed-by-multiple-gene-sequence-characterization
#2
Nomakorinte Gcebe, Victor Rutten, Nicolaas Gey van Pittius, Brendon Naicker, Anita Michel
Non-tuberculous mycobacteria (NTM) are ubiquitous in the environment and an increasing number of NTM species have been isolated and characterized from both humans and animals, highlighting the zoonotic potential of these bacteria. Host exposure to NTM may impact on cross-reactive immune responsiveness which may affect diagnosis of bovine tuberculosis and may also play a role in the variability of the efficacy of Mycobacterium bovis BCG vaccination against tuberculosis. In this study we characterized 10 NTM isolates originating from water, soil, nasal swabs of cattle and African buffalo as well as bovine tissue samples...
December 5, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27925794/endocrine-and-emotional-response-to-exclusion-among-women-and-men-cortisol-salivary-alpha-amylase-and-mood
#3
Liat Helpman, Julia Penso, Orna Zagoory-Sharon, Ruth Feldman, Eva Gilboa-Schechtman
BACKGROUND AND OBJECTIVES: Social exclusion is ubiquitous and painful. Evolutionary models indicate sex differences in coping with social stress. Recent empirical data suggests different sex patterns in hypothalamic-pituitary-adrenal (HPA) and sympathetic-adrenal-medullary (SAM) reactivity. The present study sought to test this hypothesis. DESIGN: We examined differences in endocrine and emotional response to exclusion by using a virtual ball tossing paradigm (Cyberball)...
December 7, 2016: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/27925698/frustrated-lewis-pairs-like-reactivity-of-rare-earth-metal-complexes-1-4-addition-reactions-and-polymerizations-of-conjugated-polar-alkenes
#4
Pengfei Xu, Yingming Yao, Xin Xu
Three rare-earth aryloxide ion pairs ([L1REOAr]+[B(C6F5)4]-; L1 = CH3C(2,6-iPr2C6H3N)CHC(CH3)(NCH2CH2PPh2); RE = Sc, Y, Lu; Ar = 2,6-tBu2C6H3) are reported, which feature RE/P combinations exhibiting frustrated Lewis pair (FLP)-like 1,4-addition reactions towards conjugated carbonyl substrates e.g. enone, ynone and acrylic substrates. Furthermore, these RE/P complexes are found to be effective catalysts for polymerizations of conjugated polar alkene monomers. Mechanistic studies reveal that the polymerizations are initiated by novel FLP-type 1,4-additions, rather than traditional and ubiquitous covalent RE-E (E = H, C, N, etc...
December 7, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27925403/heterogeneously-catalyzed-aerobic-oxidation-of-5-hydroxymethylfurfural-to-2-5-furandicarboxylic-acid-with-manganese-dioxide
#5
Eri Hayashi, Tasuku Komanoya, Keigo Kamata, Michikazu Hara
A simple non-precious metal catalyst system based on cost-effective and ubiquitously available MnO2, NaHCO3, and molecular oxygen was used to convert 5-hydroxymethylfurfural to 2,5-difurandicarboxylic acid as a bioplastics precursor in 91% yield. The MnO2 catalyst could be recovered by simple filtration and reused several times. The present system was also applicable to the aerobic oxidation of other biomass-derived substrates and the gram-scale oxidation of HMF to FDCA, in which 2.36 g (86% yield) of the analytically pure FDCA could be isolated...
December 7, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27924930/new-principle-for-measuring-arterial-blood-oxygenation-enabling-motion-robust-remote-monitoring
#6
Mark van Gastel, Sander Stuijk, Gerard de Haan
Finger-oximeters are ubiquitously used for patient monitoring in hospitals worldwide. Recently, remote measurement of arterial blood oxygenation (SpO2) with a camera has been demonstrated. Both contact and remote measurements, however, require the subject to remain static for accurate SpO2 values. This is due to the use of the common ratio-of-ratios measurement principle that measures the relative pulsatility at different wavelengths. Since the amplitudes are small, they are easily corrupted by motion-induced variations...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27924497/a-strategy-combining-higher-energy-c-trap-dissociation-with-neutral-loss-and-product-ion-based-ms-n-acquisition-for-global-profiling-and-structure-annotation-of-fatty-acids-conjugates
#7
Qi-Rui Bi, Jin-Jun Hou, Min Yang, Yao Shen, Peng Qi, Rui-Hong Feng, Zhuo Dai, Bing-Peng Yan, Jian-Wei Wang, Xiao-Jian Shi, Wan-Ying Wu, De-An Guo
Fatty acids conjugates (FACs) are ubiquitous but found in trace amounts in the natural world. They are composed of multiple unknown substructures and side chains. Thus, FACs are difficult to be analyzed by traditional mass spectrometric methods. In this study, an integrated strategy was developed to global profiling and targeted structure annotation of FACs in complex matrix by LTQ Orbitrap. Dicarboxylic acid conjugated bufotoxins (DACBs) in Venenum bufonis (VB) were used as model compounds. The new strategy (abbreviated as HPNA) combined higher-energy C-trap dissociation (HCD) with product ion- (PI), neutral loss- (NL) based MS(n) (n ≥ 3) acquisition in both positive-ion mode and negative-ion mode...
December 6, 2016: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/27924481/machine-learning-approaches-toward-building-predictive-models-for-small-molecule-modulators-of-mirna-and-its-utility-in-virtual-screening-of-molecular-databases
#8
Vinita Periwal, Vinod Scaria
The ubiquitous role of microRNAs (miRNAs) in a number of pathological processes has suggested that they could act as potential drug targets. RNA-binding small molecules offer an attractive means for modulating miRNA function. The availability of bioassay data sets for a variety of biological assays and molecules in public domain provides a new opportunity toward utilizing them to create models and further utilize them for in silico virtual screening approaches to prioritize or assign potential functions for small molecules...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27924291/data-on-isoaspartylation-of-neuronal-elavl-proteins
#9
Mario A Pulido, Meleeneh Kazarian DerHartunian, Prerna Sehgal, Ite A Laird-Offringa
This article contains experimental data examining the propensity of neuronal ELAVL proteins to become isoaspartylated. The data are related to the article "Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4" (M.A. Pulido, M.K. DerHartunian, Z. Qin, E.M. Chung, D.S. Kang, A.W. Woodham, J.A. Tsou, R. Klooster, O. Akbari, L. Wang, W.M. Kast, S.V. Liu, J.J.G.M. Verschuuren, D.W. Aswad, I.A. Laird-Offringa, 2016) [1], in which it was reported that the N-terminal region of recombinant human ELAVL4 protein, incubated under physiological conditions, acquires a type of highly immunogenic protein damage...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27924124/arsenic-stress-affects-the-expression-profile-of-genes-of-14-3-3-proteins-in-the-shoot-of-mycorrhiza-colonized-rice
#10
Varsha Pathare, Sudhakar Srivastava, Balasaheb V Sonawane, Penna Suprasanna
The intimate association between the arbuscular mycorrhizal fungi and host plants helps the latter in phosphate acquisition in exchange of carbohydrates and in enhanced stress tolerance. Similarly, the ubiquitous 14-3-3 protein family is known to be a major regulator of plant metabolism and stress responses. However, the involvement of mycorrhiza and plant 14-3-3 proteins interaction in plant response to environmental stimuli, such as arsenic (As) stress, is yet unknown. In this study, we analysed the impact of the As stress on the expression profile of 14-3-3 genes in the shoot of mycorrhiza colonized rice (Oryza sativa) plants...
October 2016: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/27923992/sinorhizobium-meliloti-ybey-is-an-endoribonuclease-with-unprecedented-catalytic-features-acting-as-silencing-enzyme-in-riboregulation
#11
Margarida Saramago, Alexandra Peregrina, Marta Robledo, Rute G Matos, Rolf Hilker, Javier Serrania, Anke Becker, Cecilia M Arraiano, José I Jiménez-Zurdo
Structural and biochemical features suggest that the almost ubiquitous bacterial YbeY protein may serve catalytic and/or Hfq-like protective functions central to small RNA (sRNA)-mediated regulation and RNA metabolism. We have biochemically and genetically characterized the YbeY ortholog of the legume symbiont Sinorhizobium meliloti (SmYbeY). Co-immunoprecipitation (CoIP) with a FLAG-tagged SmYbeY yielded a poor enrichment in RNA species, compared to Hfq CoIP-RNA uncovered previously by a similar experimental setup...
December 6, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27923613/an-arabidopsis-thaliana-receptor-dead-kinase1-rdk1-gene-functions-as-a-positive-regulator-in-plant-responses-to-aba
#12
Dhinesh Kumar, Ritesh Kumar, Dongwon Baek, Tae-Kyung Hyun, Woo Sik Chung, Dae-Jin Yun, Jae-Yean Kim
Abscisic acid (ABA) is a major phytohormone involved in important stress-related and developmental plant processes. Membrane-delimited ABA signal transduction plays an important role in early ABA signaling, but the molecular mechanisms connecting core signaling components to the plasma membrane (PM) are unclear. Plants have evolved a large number of receptor-like kinases (RLKs) to modulate diverse biological processes by perceiving extracellular stimuli and activating downstream signaling responses. Here, a putative leucine-rich repeat (LRR)-RLK gene named RECEPTOR DEAD KINASE1 (AtRDK1) was identified and characterized in Arabidopsis thaliana...
December 3, 2016: Molecular Plant
https://www.readbyqxmd.com/read/27923199/the-importance-of-vial-composition-in-hplc-analysis-an-unusual-case-of-phosphorous-pseudorotation
#13
Rebecca Arvary, Ian Mangion
Glass HPLC vials are ubiquitous in analytical laboratories and vendors have developed many varieties to meet the various needs of scientists. As such there may be multiple types of vials being used simultaneously in a single laboratory without much consideration as to which is best suited for analytical method development and validation. This study highlights the possibility of vial composition as a potential factor that impacts solution stability. Here we describe a case where the type of HPLC vial used results in an interesting phosphorous pseudorotation driven by the mild alkalinity of glass...
October 6, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27922613/elements-of-biological-oscillations-in-time-and-space
#14
Yangxiaolu Cao, Allison Lopatkin, Lingchong You
Oscillations in time and space are ubiquitous in nature and play critical roles in dynamic cellular processes. Although the molecular mechanisms underlying the generation of the dynamics are diverse, several distinct regulatory elements have been recognized as being critical in producing and modulating oscillatory dynamics. These include negative and positive feedback, time delay, nonlinearity in regulation, and random fluctuations ('noise'). Here we discuss the specific roles of these five elements in promoting or attenuating oscillatory dynamics, by drawing on insights from quantitative analyses of natural or synthetic biological networks...
December 6, 2016: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/27920768/the-shifts-of-diazotrophic-communities-in-spring-and-summer-associated-with-coral-galaxea-astreata-pavona-decussata-and-porites-lutea
#15
Yanying Zhang, Qingsong Yang, Juan Ling, Joy D Van Nostrand, Zhou Shi, Jizhong Zhou, Junde Dong
The coral holobiont often resides in oligotrophic waters; both coral cells and their symbiotic dinoflagellates possess ammonium assimilation enzymes and potentially benefit from the nitrogen fixation of coral-associated diazotrophs. However, the seasonal dynamics of coral-associated diazotrophs are not well characterized. Here, the seasonal variations of diazotrophic communities associated with three corals, Galaxea astreata, Pavona decussata, and Porites lutea, were studied using nifH gene amplicon pyrosequencing techniques...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27920252/group-i-paks-promote-skeletal-myoblast-differentiation-in-vivo-and-in-vitro
#16
Giselle A Joseph, Min Lu, Maria Radu, Jennifer K Lee, Steven J Burden, Jonathan Chernoff, Robert S Krauss
Skeletal myogenesis is regulated by signal transduction, but the factors and mechanisms involved are not well understood. The group I Paks, Pak1 and Pak2, are related protein kinases and direct effectors of Cdc42 and Rac1. Group I Paks are ubiquitously expressed and specifically required for myoblast fusion in Drosophila We report that both Pak1 and Pak2 are activated during mammalian myoblast differentiation. One pathway of activation is initiated by N-cadherin ligation, and involves the cadherin co-receptor Cdo with its downstream effector, Cdc42...
December 5, 2016: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/27919888/identification-of-a-novel-lincomycin-resistance-mutation-associated-with-activation-of-antibiotic-production-in-streptomyces-coelicolor-a3-2
#17
Guojun Wang, Masumi Izawa, Xiaoge Yang, Dongbo Xu, Yukinori Tanaka, Kozo Ochi
Comparative genome sequencing analysis of a lincomycin-resistant strain of Streptomyces coelicolor A3 (2) and the wild type strain identified a novel mutation conferring a high level of lincomycin resistance. Surprisingly, the new mutation was an in-frame DNA deletion in the genes SCO4597-SCO4598, resulting in formation of the hybrid gene linR SCO4597 and SCO4598 encode two histidine kinases, which, together with SCO4596, encoding a response regulator, constitute a unique two-component system. Sequence analysis indicated that these three genes and their arrangement patterns are ubiquitous among all Streptomyces genomes sequenced to date, suggesting these genes play important regulatory roles...
December 5, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27919756/molecular-identification-and-functional-delineation-of-a-glutathione-reductase-homologue-from-disk-abalone-haliotis-discus-discus-insights-as-a-potent-player-in-host-antioxidant-defense
#18
H M L P B Herath, P D S U Wickramasinghe, S D N K Bathige, R G P T Jayasooriya, Gi-Young Kim, Myoung Ae Park, Chul Kim, Jehee Lee
Glutathione reductase (GSR) is an enzyme that catalyzes the biochemical conversion of oxidized glutathione (GSSG) into the reduced form (GSH). Since the ratio between the two forms of glutathione (GSH/GSSG) is important for the optimal function of GSH to act as an antioxidant against H2O2, the contribution of GSR as an enzymatic regulatory agent to maintain the proper ratio is essential. Abalones are marine mollusks that frequently encounter environmental factors that can trigger the overproduction of reactive oxygen species (ROS) such as H2O2...
December 2, 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27919712/extracts-from-two-ubiquitous-mediterranean-plants-ameliorate-cellular-and-animal-models-of-neurodegenerative-proteinopathies
#19
Michelle Briffa, Stephanie Ghio, Johanna Neuner, Alison J Gauci, Rebecca Cacciottolo, Christelle Marchal, Mario Caruana, Christophe Cullin, Neville Vassallo, Ruben J Cauchi
A signature feature of age-related neurodegenerative proteinopathies is the misfolding and aggregation of proteins, typically amyloid-β (Aβ) in Alzheimer's disease (AD) and α-synuclein (α-syn) in Parkinson's disease (PD), into soluble oligomeric structures that are highly neurotoxic. Cellular and animal models that faithfully replicate the hallmark features of these disorders are being increasing exploited to identify disease-modifying compounds. Natural compounds have been identified as a useful source of bioactive molecules with promising neuroprotective capabilities...
December 2, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27919551/defining-the-core-microbiome-in-corals-microbial-soup
#20
REVIEW
Alejandra Hernandez-Agreda, Ruth D Gates, Tracy D Ainsworth
Corals are considered one of the most complex microbial biospheres studied to date, hosting thousands of bacterial phylotypes in species-specific associations. There are, however, substantial knowledge gaps and challenges in understanding the functional significance of bacterial communities and bacterial symbioses of corals. The ubiquitous nature of some bacterial interactions has only recently been investigated and an accurate differentiation between the healthy (symbiotic) and unhealthy (dysbiotic) microbial state has not yet been determined...
December 2, 2016: Trends in Microbiology
keyword
keyword
69814
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"