keyword
MENU ▼
Read by QxMD icon Read
search

curious

keyword
https://www.readbyqxmd.com/read/28231704/genetic-correlations-between-behavioural-responses-and-performance-traits-in-laying-hens
#1
Iwona Rozempolska-Rucińska, Grzegorz Zięba, Lucyna Kibała, Tomasz Paweł Próchniak, Marek Łukaszewicz
The aim of the study was to evaluate genetic correlations between the behavioural profile and performance in laying hens as an indirect answer to the question whether the observed behavioural responses are associated with increased levels of stress in these birds. The assessment of birds' temperament was carried out using the Novel Objects Test. The behavioural test was conducted in two successive generations comprising 9483 Rhode Island White birds (approx. 4700 individuals per generation) and 4326 Rhode Island Red birds (approx...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28227037/an-end-to-end-secure-cbir-over-encrypted-medical-database
#2
Reda Bellafqira, Gouenou Coatrieux, Dalel Bouslimi, Gwenole Quellec, Reda Bellafqira, Gouenou Coatrieux, Dalel Bouslimi, Gwenole Quellec, Gwenole Quellec, Reda Bellafqira, Dalel Bouslimi, Gouenou Coatrieux
In this paper, we propose a new secure content based image retrieval (SCBIR) system adapted to the cloud framework. This solution allows a physician to retrieve images of similar content within an outsourced and encrypted image database, without decrypting them. Contrarily to actual CBIR approaches in the encrypted domain, the originality of the proposed scheme stands on the fact that the features extracted from the encrypted images are themselves encrypted. This is achieved by means of homomorphic encryption and two non-colluding servers, we however both consider as honest but curious...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28223501/biosynthetic-pathway-of-aliphatic-formates-via-a-baeyer-villiger-oxidation-in-mechanism-present-in-astigmatid-mites
#3
Nobuhiro Shimizu, Daisuke Sakata, Eric A Schmelz, Naoki Mori, Yasumasa Kuwahara
Astigmatid mites depend on bioactive glandular secretions, pheromones, and defensive agents to mediate intra- and interspecies interactions. Aliphatic formates, such as (Z,Z)-8,11-heptadecadienyl formate (8,11-F17) and (Z)-8-heptadecenyl formate (8-F17), are rarely encountered natural products that are abundant in Sancassania sp. Sasagawa (Acari: Acaridae) mite secretions. Linoleic acid and oleic acid are predicted as key intermediates in the synthesis of the closely related aliphatic formates. To gain insight in this biosynthetic pathway, acarid mite feeding experiments were conducted using (13)C-labeled precursors to precisely track incorporation...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28215044/developing-caring-conversations-in-care-homes-an-appreciative-inquiry
#4
Belinda Dewar, Tamsin MacBride
Relationship-centred practice is key to delivering quality care in care homes. Evidence is strong about the centrality of human interaction in developing relationships that promote dignity and compassion. The Caring Conversations framework is a framework for delivering compassionate care based on human interactions that was developed in the acute healthcare setting. The key attributes are: be courageous, connect emotionally, be curious, consider other perspectives, collaborate, compromise and celebrate. This paper reports on a study to explore its relevance to the care home setting and the development of an educational intervention, based on the framework, to enhance development of human interaction...
February 19, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28212816/social-science-s-curious-war-with-pop-culture-and-how-it-was-lost-the-media-violence-debate-and-the-risks-it-holds-for-social-science
#5
REVIEW
Christopher J Ferguson, Eugene Beresin
For nearly half a century, psychologists, pediatricians and psychiatrists have studied the potential impact of media violence on aggression and societal violence, particularly among youth. Despite hundreds of studies, scholars have failed to find consensus on potential effects. Nonetheless, professional organizations such as the American Academy of Pediatrics and American Psychological Association have released policy statements conclusively linking violent media to societal concerns. In reaction, some scholars have accused these professional groups of distorting evidence and failing to inform the public of the inconsistent nature of studies in this field...
February 14, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28198489/negative-effects-of-divalent-mineral-cations-on-the-bioaccessibility-of-carotenoids-from-plant-food-matrices-and-related-physical-properties-of-gastro-intestinal-fluids
#6
Joana Corte-Real, Marie Bertucci, Christos Soukoulis, Charles Desmarchelier, Patrick Borel, Elke Richling, Lucien Hoffmann, Torsten Bohn
Carotenoid intake and tissue levels have been frequently associated with reduced risk of chronic diseases. However, their bioavailability is low and influenced by many dietary related parameters. Divalent mineral cations have been suggested to interfere with carotenoid digestion and to hamper micellarization, a prerequisite for their uptake, via complexation of bile salts and precipitation of fatty acids. In the present investigation, we have evaluated the effects of increasing concentrations of magnesium (0-300 mg L(-1)), calcium (0-1500 mg L(-1)), zinc (0-200 mg L(-1)), and sodium (0-1500 mg L(-1); control monovalent cation), on carotenoid bioaccessibility from frequently consumed food items rich in carotenoids (tomato juice, carrot juice, apricot nectar, spinach and field salad), following simulated gastro-intestinal digestion...
February 15, 2017: Food & Function
https://www.readbyqxmd.com/read/28191472/suppression-of-excessive-histone-deacetylases-activity-in-diabetic-hearts-attenuates-myocardial-ischemia-reperfusion-injury-via-mitochondria-apoptosis-pathway
#7
Yang Wu, Yan Leng, Qingtao Meng, Rui Xue, Bo Zhao, Liying Zhan, Zhongyuan Xia
Background. Histone deacetylases (HDACs) play a pivotal role in signaling modification and gene transcriptional regulation that are essential for cardiovascular pathophysiology. Diabetic hearts with higher HDACs activity were more vulnerable to myocardial ischemia/reperfusion (MI/R) injury compared with nondiabetic hearts. We are curious about whether suppression of excessive HDACs activity in diabetic heart protects against MI/R injury. Methods. Diabetic rats were subjected to 45 min of ischemia, followed by 3 h of reperfusion...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28191370/overestimating-overdiagnosis-in-breast-cancer-screening
#8
EDITORIAL
Alan Hollingsworth
Overdiagnosis in breast cancer has been a focus of increasing concern with wide ranges of calculations made indirectly through the study of prospective randomized trials and analyses of large registries. While most admit that some degree of overdiagnosis is inherent with ductal carcinoma in situ (DCIS), the rate of overdiagnosis with invasive disease is highly controversial. Although it is generally accepted that overdiagnosis is calculated through indirect means and deductive reasoning, this is not entirely the case...
January 9, 2017: Curēus
https://www.readbyqxmd.com/read/28185164/in-vivo-uptake-of-rare-earth-metals-by-triple-negative-breast-cancer-cells
#9
Luca Roncati, Antonietta Morena Gatti, Giuseppe Barbolini, Francesco Piscioli, Teresa Pusiol, Antonio Maiorana
Rare earth metals (REM) are a group of 17 chemical elements in the periodic table, namely scandium (Sc), yttrium (Y) and the lanthanides. In relation to atomic volume and geological behavior, the lanthanides are further subdivided into light, medium and heavy REM. They find many applications in the technological field; however, their impact on the human health is still conflicting and, for many aspects, unknown. During a research program carried on 113 cases of female breast cancer, immunohistochemically categorized in Her2-positive (29 cases), Her2-negative (57 cases) and triple negative (27 cases), aimed to evaluate the role of environmental particulate in carcinogenesis by elemental microanalysis, for the first time in literature we have detected a REM uptake, in detail europium (Eu), dysprosium (Dy) and praseodymium (Pr), inside the neoplastic cells belonging to a single triple negative breast cancer...
February 9, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28174316/density-dependent-recycling-promotes-the-long-term-survival-of-bacterial-populations-during-periods-of-starvation
#10
Sotaro Takano, Bogna J Pawlowska, Ivana Gudelj, Tetsuya Yomo, Saburo Tsuru
: The amount of natural resources in the Earth's environment is in flux, which can trigger catastrophic collapses of ecosystems. How populations survive under nutrient-poor conditions is a central question in ecology. Curiously, some bacteria persist for a long time in nutrient-poor environments. Although this survival may be accomplished through cell death and the recycling of dead cells, the importance of these processes and the mechanisms underlying the survival of the populations have not been quantitated...
February 7, 2017: MBio
https://www.readbyqxmd.com/read/28168063/a-rare-case-of-vancomycin-induced-linear-immunoglobulin-a-bullous-dermatosis
#11
Pinky Jha, Kurtis Swanson, Jeremiah Stromich, Basia M Michalski, Edit Olasz
Linear IgA bullous dermatosis (LABD) is an autoimmune vesiculobullous disease, which is typically idiopathic but can also rarely be caused by medications or infections. Vancomycin is the most common drug associated with LABD. Lesions typically appear 24 hours to 15 days after the first dose of vancomycin. It is best characterized pathologically by subepidermal bulla (blister) formation with linear IgA deposition at the dermoepidermal junction. Here we report an 86-year-old male with a history of left knee osteoarthritis who underwent a left knee arthroplasty and subsequently developed a prosthetic joint infection...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/28163047/curious-case-of-wheezing-carcinoid-heart-disease
#12
Dhaval Desai, M Fuad Jan, Nataly Stenzel, Paul Werner, A Jamil Tajik
No abstract text is available yet for this article.
February 2, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28153580/from-planar-cell-polarity-to-ciliogenesis-and-back-the-curious-tale-of-the-ppe-and-cplane-proteins
#13
REVIEW
Paul N Adler, John B Wallingford
Why some genes are more popular than others remains an open question, but one example of this phenomenon involves the genes controlling planar cell polarity (PCP), the polarization of cells within a plane of a tissue. Indeed, the so-called 'core' PCP genes such as dishevelled, frizzled, and prickle have been extensively studied both in animal models and by human genetics. By contrast, other genes that influence PCP signaling have received far less attention. Among the latter are inturned, fuzzy, and fritz, but recent work should bring these once obscure regulators into the limelight...
January 30, 2017: Trends in Cell Biology
https://www.readbyqxmd.com/read/28153532/fty720-fingolimod-reverses-%C3%AE-synuclein-induced-downregulation-of-brain-derived-neurotrophic-factor-mrna-in-oln-93-oligodendroglial-cells
#14
Ismael Segura-Ulate, Barbara Yang, Javier Vargas-Medrano, Ruth G Perez
Multiple system atrophy (MSA) is a demyelinating neurodegenerative disorder characterized by accumulation of aggregated α-synuclein (aSyn) inside oligodendrocyte precursors, mature oligodendroglia, and neurons. MSA dysfunction is associated with loss of trophic factor production by glial and neuronal cells. Here, we report that recombinant wild type human aSyn uptake by OLN-93, an oligodendroglia cell-line, reduced brain-derived neurotrophic factor (BDNF) expression. Furthermore, OLN-93 cells stably transfected with human wild type or an MSA-associated mutant aSyn, A53E that produces neuronal and glial inclusions, reduced BDNF mRNA to nearly unmeasurable qPCR levels...
January 31, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28152065/microsporidia-infection-impacts-the-host-cell-s-cycle-and-reduces-host-cell-apoptosis
#15
Raquel Martín-Hernández, Mariano Higes, Soledad Sagastume, Ángeles Juarranz, Joyce Dias-Almeida, Giles E Budge, Aránzazu Meana, Neil Boonham
Intracellular parasites can alter the cellular machinery of host cells to create a safe haven for their survival. In this regard, microsporidia are obligate intracellular fungal parasites with extremely reduced genomes and hence, they are strongly dependent on their host for energy and resources. To date, there are few studies into host cell manipulation by microsporidia, most of which have focused on morphological aspects. The microsporidia Nosema apis and Nosema ceranae are worldwide parasites of honey bees, infecting their ventricular epithelial cells...
2017: PloS One
https://www.readbyqxmd.com/read/28137328/impact-of-dietary-fat-composition-on-prediabetes-a-12-year-follow-up-study
#16
Sridevi Krishnan, Lyn M Steffen, Chad M Paton, Jamie A Cooper
OBJECTIVE: Dietary fatty acid composition likely affects prediabetic conditions such as isolated impaired fasting glucose (IFG) or impaired glucose tolerance (IGT); however, this risk has not been evaluated in a large population nor has it been followed prospectively. DESIGN: Diet, physical activity, anthropometric, socio-economic and blood glucose data from the Atherosclerosis Risk in Communities (ARIC) study were obtained from BioLINCC. Cox proportional hazards regression models were used to evaluate associations of dietary SFA, MUFA, PUFA, n-3 fatty acid (FA) and n-6 FA intakes with incidence of one (isolated IFG) or two (IFG with IGT) prediabetic conditions at the end of 12-year follow-up...
January 31, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28135270/optimal-sequential-immunization-can-focus-antibody-responses-against-diversity-loss-and-distraction
#17
Shenshen Wang
Affinity maturation is a Darwinian process in which B lymphocytes evolve potent antibodies to encountered antigens and generate immune memory. Highly mutable complex pathogens present an immense antigenic diversity that continues to challenge natural immunity and vaccine design. Induction of broadly neutralizing antibodies (bnAbs) against this diversity by vaccination likely requires multiple exposures to distinct but related antigen variants, and yet how affinity maturation advances under such complex stimulation remains poorly understood...
January 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28127818/ablating-the-obscure-the-curious-case-of-the-vein-of-marshall
#18
EDITORIAL
Bruce B Lerman
No abstract text is available yet for this article.
January 27, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28114637/high-prices-for-drugs-with-generic-alternatives-the-curious-case-of-duexis
#19
Aaron Hakim, Joseph S Ross
No abstract text is available yet for this article.
January 23, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28114434/co-infecting-reptarenaviruses-can-be-vertically-transmitted-in-boa-constrictor
#20
Saskia Keller, Udo Hetzel, Tarja Sironen, Yegor Korzyukov, Olli Vapalahti, Anja Kipar, Jussi Hepojoki
Boid inclusion body disease (BIBD) is an often fatal disease affecting mainly constrictor snakes. BIBD has been associated with infection, and more recently with coinfection, by various reptarenavirus species (family Arenaviridae). Thus far BIBD has only been reported in captive snakes, and neither the incubation period nor the route of transmission are known. Herein we provide strong evidence that co-infecting reptarenavirus species can be vertically transmitted in Boa constrictor. In total we examined five B...
January 2017: PLoS Pathogens
keyword
keyword
6980
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"