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https://www.readbyqxmd.com/read/29331570/meningeal-marginal-zone-b-cell-lymphoma-the-meningioma-trap
#1
Alexandre Villeneuve, François Rubin, Pierre Bonfils
OBJECTIVE: To report a case of marginal zone MALT lymphoma of the temporal dura mater, initially mistaken for temporal meningioma. CASE REPORT: A 60-year-old immunocompetent woman, followed for more than 10 years for temporal meningioma causing vertigo and mixed hearing loss, presented with cervical lymphadenopathy, revealing marked progression of an intracranial lesion, leading to a diagnosis of marginal zone MALT lymphoma based on histological examination of a cervical lymph node...
January 10, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29290031/specialized-plant-metabolism-characteristics-and-impact-on-target-molecule-biotechnological-production
#2
REVIEW
Hélio Nitta Matsuura, Sonia Malik, Fernanda de Costa, Morteza Yousefzadi, Mohammad Hossein Mirjalili, Randolph Arroo, Avninder S Bhambra, Miroslav Strnad, Mercedes Bonfill, Arthur Germano Fett-Neto
Plant secondary metabolism evolved in the context of highly organized and differentiated cells and tissues, featuring massive chemical complexity operating under tight environmental, developmental and genetic control. Biotechnological demand for natural products has been continuously increasing because of their significant value and new applications, mainly as pharmaceuticals. Aseptic production systems of plant secondary metabolites have improved considerably, constituting an attractive tool for increased, stable and large-scale supply of valuable molecules...
December 30, 2017: Molecular Biotechnology
https://www.readbyqxmd.com/read/29287622/transcranial-magnetic-stimulation-and-subjective-tinnitus-a-review-of-the-literature-2014-2016
#3
A Londero, P Bonfils, J P Lefaucheur
Subjective tinnitus is a symptom in many ENT pathologies, for which there is no curative treatment. It may be poorly tolerated by some patients, who develop attention or sleep disorder or even major anxiety and depression, severely impairing quality of life. Pathophysiological models of the genesis and maintenance of tinnitus symptomatology highlight maladaptive cerebral plasticity induced by peripheral hearing loss. Although not fully elucidated, these changes in neuronal activity are the target of various attempts at neuromodulation, particularly using repetitive transcranial magnetic stimulation (rTMS), which has been the focus of various clinical studies and meta-analyses...
December 26, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29283434/elevation-of-the-head-during-intensive-care-management-in-people-with-severe-traumatic-brain-injury
#4
REVIEW
Jose D Alarcon, Andres M Rubiano, David O Okonkwo, Jairo Alarcón, Maria José Martinez-Zapata, Gerard Urrútia, Xavier Bonfill Cosp
BACKGROUND: Traumatic brain injury (TBI) is a major public health problem and a fundamental cause of morbidity and mortality worldwide. The burden of TBI disproportionately affects low- and middle-income countries. Intracranial hypertension is the most frequent cause of death and disability in brain-injured people. Special interventions in the intensive care unit are required to minimise factors contributing to secondary brain injury after trauma. Therapeutic positioning of the head (different degrees of head-of-bed elevation (HBE)) has been proposed as a low cost and simple way of preventing secondary brain injury in these people...
December 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29258300/orbital-misalignment-of-the-neptune-mass-exoplanet-gj-436b-with-the-spin-of-its-cool-star
#5
Vincent Bourrier, Christophe Lovis, Hervé Beust, David Ehrenreich, Gregory W Henry, Nicola Astudillo-Defru, Romain Allart, Xavier Bonfils, Damien Ségransan, Xavier Delfosse, Heather M Cegla, Aurélien Wyttenbach, Kevin Heng, Baptiste Lavie, Francesco Pepe
The angle between the spin of a star and the orbital planes of its planets traces the history of the planetary system. Exoplanets orbiting close to cool stars are expected to be on circular, aligned orbits because of strong tidal interactions with the stellar convective envelope. Spin-orbit alignment can be measured when the planet transits its star, but such ground-based spectroscopic measurements are challenging for cool, slowly rotating stars. Here we report the three-dimensional characterization of the trajectory of an exoplanet around an M dwarf star, derived by mapping the spectrum of the stellar photosphere along the chord transited by the planet...
December 18, 2017: Nature
https://www.readbyqxmd.com/read/29222942/microbial-communities-in-natural-rubber-coagula-during-maturation-impacts-on-technological-properties-of-dry-natural-rubber
#6
Mélanie Salomez, Maeva Subileau, Tatiana Vallaeys, Sylvain Santoni, Fréderic Bonfils, Jérôme Sainte-Beuve, Jutharat Intapun, Françoise Granet, Laurent Vaysse, Éric Dubreucq
AIM: To characterize microbial communities present in natural rubber coagula from Hevea brasiliensis latex during maturation and identify microbial taxa (bacteria and fungi) having an impact on dry natural rubber properties. METHODS AND RESULTS: Microbial community dynamics in natural rubber coagula maturated under controlled conditions were compared and related with the evolution of dry natural rubber properties. The pyrosequencing of 16S (119,837 effective reads) and 18S (131,879 effective reads) rRNA gene regions was performed on 21 samples covering different maturation times and two aeration conditions...
December 9, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29212556/clinical-interval-and-diagnostic-characteristics-in-a-cohort-of-bladder-cancer-patients-in-spain-a-multicenter-observational-study
#7
Xavier Bonfill, María José Martinez-Zapata, Robin W M Vernooij, María José Sánchez, María Morales Suárez-Varela, Javier De la Cruz, José Ignacio Emparanza, Montserrat Ferrer, José Ignacio Pijoan, Joan Palou, Stefanie Schmidt, Eva Madrid, Víctor Abraira, Javier Zamora
OBJECTIVE: We performed a cohort study in seven hospitals in Spain to determine the clinical characteristics of incident patients with bladder cancer, the diagnostic process, and the conditions that might affect health care interval times. RESULTS: 314 patients with bladder cancer were included, 70.3 (Standard Deviation [SD] 11.2) years old and 85.0% male. Clinical stage was T1 in 45.9% of patients. The median interval time between first consultation and diagnosis was of 104...
December 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29209024/future-loss-of-arctic-sea-ice-cover-could-drive-a-substantial-decrease-in-california-s-rainfall
#8
Ivana Cvijanovic, Benjamin D Santer, Céline Bonfils, Donald D Lucas, John C H Chiang, Susan Zimmerman
From 2012 to 2016, California experienced one of the worst droughts since the start of observational records. As in previous dry periods, precipitation-inducing winter storms were steered away from California by a persistent atmospheric ridging system in the North Pacific. Here we identify a new link between Arctic sea-ice loss and the North Pacific geopotential ridge development. In a two-step teleconnection, sea-ice changes lead to reorganization of tropical convection that in turn triggers an anticyclonic response over the North Pacific, resulting in significant drying over California...
December 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/29180574/mir-126-5p-promotes-retinal-endothelial-cell-survival-through-setd5-regulatio-in-neurons
#9
Villain Gaëlle, Poissonnier Loïc, Noueihed Baraa, Bonfils Gaëlle, Rivera Jose Carlos, Chemtob Sylvain, Soncin Fabrice, Mattot Virginie
MicroRNAs are key regulators of angiogenesis, as illustrated by the vascular defects observed in miR-126-deficient animals. While the miR-126 duplex gives rise to two mature microRNAs (miR-126-3p and -5p), these defects were attributed to the loss of miR-126-3p while the role of miR-126-5p during normal angiogenesis in vivo remains unknown. Here, we show that miR-126-5p is expressed in endothelial but also by retinal ganglion cells (RGC) of the postnatal retina and participates in protecting endothelial cells from apoptosis during the establishment of the retinal vasculature...
November 27, 2017: Development
https://www.readbyqxmd.com/read/29164603/18f-pet-with-florbetapir-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#10
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Xavier Bonfill Cosp, Leon Flicker
BACKGROUND: 18F-florbetapir uptake by brain tissue measured by positron emission tomography (PET) is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using amyloid biomarkers tests like 18F-florbetapir...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164602/18f-pet-with-flutemetamol-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#11
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Leon Flicker, Xavier Bonfill Cosp
BACKGROUND: 18F-flutemetamol uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and the confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using some amyloid biomarkers tests like 18F-flutemetamol...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164600/18f-pet-with-florbetaben-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#12
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Leon Flicker, Xavier Bonfill Cosp
BACKGROUND: 18F-florbetaben uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using some amyloid biomarkers tests like 18F-florbetaben...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29159793/curative-radiation-therapy-for-very-elderly-bladder-cancer-patients-with-localized-disease
#13
M Bonet, T Bonfill, M Nuñez, L De Verdonces, E Mur, E Gallardo, L Fernandez-Morales, A Aguilar, J Prats, M Arenas
PURPOSE: To report the outcomes of a cohort of very elderly muscle-invasive bladder cancer (MIBC) patients treated with contemporary 3D-conformal radiation therapy (3D-CRT) with or without concurrent chemotherapy, after transurethral resection of bladder tumor (TURBT). METHODS: From February 2010 to January 2014, a total of 41 patients older than 75 years, with T2-3 N0-1 high-grade MIBC, a Karnofsky index (KI) of at least 90% and/or a Barthel scale score of at least 95, were treated with TURBT followed by radiotherapy (RT) with or without chemotherapy, and were prospectively followed-up...
November 20, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29150349/frontal-sinus-revision-rate-after-nasal-polyposis-surgery-including-frontal-recess-clearance-and-middle-turbinectomy-a-long-term-analysis
#14
Hakim Benkhatar, Idir Khettab, Philippe Sultanik, Ollivier Laccourreye, Pierre Bonfils
OBJECTIVE: To determine the frontal sinus revision rate after nasal polyposis (NP) surgery including frontal recess clearance (FRC) and middle turbinectomy (MT), to search for predictive factors and to analyse surgical management. METHODS: Longitudinal analysis of 153 patients who consecutively underwent bilateral sphenoethmoidectomy with FRC and MT for NP with a minimum follow-up of 7 years. Decision of revision surgery was made in case of medically refractory chronic frontal sinusitis or frontal mucocele...
November 14, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29103474/effectiveness-and-cost-effectiveness-of-double-reading-in-digital-mammography-screening-a-systematic-review-and-meta-analysis
#15
Margarita Posso, Teresa Puig, Misericòrdia Carles, Montserrat Rué, Carlos Canelo-Aybar, Xavier Bonfill
PURPOSE: Double reading is the strategy of choice for mammogram interpretation in screening programmes. It remains, however, unknown whether double reading is still the strategy of choice in the context of digital mammography. Our aim was to determine the effectiveness and cost-effectiveness of double reading versus single reading of digital mammograms in screening programmes. METHODS: We performed a systematic review by searching the PubMed, Embase, and Cochrane Library databases up to April 2017...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29098554/seom-clinical-guideline-in-nasopharynx-cancer-2017
#16
M Pastor, A Lopez Pousa, E Del Barco, P Perez Segura, B Gonzalez Astorga, B Castelo, T Bonfill, J Martinez Trufero, J Jose Grau, R Mesia
Nasopharyngeal carcinoma (NPC) is distinct from other cancers of the head and neck in biology, epidemiology, histology, natural history, and response to treatment. Radiation therapy is an essential component of curative-intent of non-disseminated disease and the association of chemotherapy improves the rates of survival. In the case of metastatic disease stages, treatment requires platinum/gemcitabine-based chemotherapy and patients may achieve a long survival time.
November 2, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29077821/novel-stabilization-technique-for-insertion-of-bonfils-intubating-endoscope-the-pool-cue-grip
#17
K Singh, R Seebaransingh
No abstract text is available yet for this article.
November 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29064949/metacognition-is-necessary-for-the-emergence-of-motivation-in-people-with-schizophrenia-spectrum-disorders-a-necessary-condition-analysis
#18
Lauren Luther, Kelsey A Bonfils, Ruth L Firmin, Kelly D Buck, Jimmy Choi, Giancarlo Dimaggio, Raffaele Popolo, Kyle S Minor, Paul H Lysaker
Metacognition deficits are a putative cause of reduced motivation in people with schizophrenia spectrum disorders. However, it is unclear whether certain levels of metacognition are necessary for motivation to emerge. This study used a Necessary Condition Analysis to test whether metacognition was necessary for the presence of motivation and to identify the minimum level of metacognition necessary for high motivation to be possible in people with schizophrenia spectrum disorders (N = 175). Participants completed clinician-rated measures of metacognition and motivation...
October 23, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28973390/association-of-krouse-classification-for-sinonasal-inverted-papilloma-with-recurrence-a-systematic-review-and-meta-analysis
#19
Quentin Lisan, Antoine Moya-Plana, Pierre Bonfils
Importance: The risk factors for the recurrence of sinonasal inverted papilloma are still unclear. Objective: To investigate the potential association between the Krouse classification and the recurrence rates of sinonasal inverted papilloma. Data Sources: The EMBASE and MEDLINE databases were searched for the period January 1, 1964, through September 30, 2016, using the following search strategy: (paranasal sinuses [Medical Subject Headings (MeSH) terms] OR sinonasal [all fields]) AND (inverted papilloma [MeSH terms] OR (inverted [all fields] AND papilloma [all fields])...
November 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28928475/isolation-of-the-antibiotic-methyl-r-e-3-1-hydroxy-4-oxocyclopent-2-en-1-yl-acrylate-ea-2801-from-trichoderma-atroviridae
#20
Emilie Adelin, Géraldine Le Goff, Pascal Retailleau, Mercedes Bonfill, Jamal Ouazzani
The endophytic Trichoderma atroviridae UB-LMA was isolated as a symbiont of Taxus baccata and analyzed for its antimicrobial activity. By applying an original approach consisting of solid-state cultivation coupled with solid-phase extraction, a new methyl (R,E)-3-(1-hydroxy-4-oxocyclopent-2-en-1-yl)-acrylate derivative named EA-2801 (1) was isolated together with the previously reported isonitrin A and dermadin methyl ester. The chemical structure of 1 was determined by NMR and MS. Compound 1 showed antimicrobial activity against a panel of Gram-positive and -negative bacteria...
November 2017: Journal of Antibiotics
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