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Idiopathic granulomatous mastitis

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https://www.readbyqxmd.com/read/28931582/steroids-administered-after-vacuum-assisted-biopsy-in-the-management-of-idiopathic-granulomatous-mastitis
#1
J Q Deng, L Yu, Y Yang, X J Feng, J Sun, J Liu, F S Fan, L Q Liao
AIMS: The aetiology and treatment options for idiopathic granulomatous mastitis (IGM) are controversial. The aim was to study the clinical and diagnostic features and discuss medical and surgical treatment for IGM in our patients. METHODS: Sixty-five patients who met the histological criteria for IGM were retrospectively studied. The diagnosis of IGM was confirmed using Mammotome (an ultrasound-guided, vacuum-assisted biopsy system), core needle biopsy, quadrantectomy or segmental resection...
October 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28856149/is-idiopathic-granulomatous-mastitis-a-surgical-disease-the-jury-is-still-out
#2
Demetrios Moris, Christos Damaskos, Spyridon Davakis, Michail Vailas, Nikolaos Garmpis, Eleftherios Spartalis, Michael Kontos, Konstantinos Kontzoglou
Idiopathic granulomatous mastitis (IGM), is a rare entity of chronic inflammatory disorder of the breast of unknown etiology. Very few cases have been described so far, almost exclusively in women. Here we describe a case of IGM in a 53-year-old man presented with a right breast mass, progressively enlarging during the last 6 months. Due to the findings of clinical examination and CT-scan, the suspicion for a potentially malignant lesion was given and the decision for surgical resection was made. Microscopic analysis of the specimen showed non-caseating granulomas around mammary lobules, findings compatible with IGM...
August 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28845595/idiopathic-granulomatous-mastitis-associated-with-hyperprolactinemia-a-nonoperative-approach
#3
John Li, Hugh P McGregor
There is increasing evidence associating idiopathic granulomatous mastitis (IGM) with hyperprolactinemia. All documented cases have involved the patient having at least one operative procedure before the association has been made. We present a 55 year old female with IGM associated with risperidone induced hyperprolactinemia. She was successfully treated with a dopamine agonist, bromocriptine. We demonstrated that complete resolution can be achieved without surgical intervention, by targeting serum prolactin levels...
August 27, 2017: Breast Journal
https://www.readbyqxmd.com/read/28764247/idiopathic-granulomatous-mastitis-a-clinical-puzzle-in-breast-lump-cases
#4
Vivek G Nath, Rakesh Sahoo, Avinash Sahoo, Jithendra Kumar Barad, K A Arun
Idiopathic granulomatous mastitis (IGM) is a rare benign disease, characterized by chronic inflammation and granulomatous disease process. A middle aged lady with breast lump for six months with equivocal mammographic and ultrasound results underwent lumpectomy and biopsy. Ruling out all other possible granulomatous diseases and malignancy, a diagnosis of IGM was made. IGM becomes clinically significant as it closely mimics carcinoma breast and some inflammatory and infectious pathology.
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28749045/factors-related-to-recurrence-of-idiopathic-granulomatous-mastitis-what-do-we-learn-from-a-multicentre-study
#5
Erdal Uysal, Atilla Soran, Efe Sezgin
BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast with unknown aetiology. Its treatment is controversial and the recurrence rate is high. The objectives of this study were to examine the demographic, sociocultural and clinical characteristics observed among a large cohort of IGM patients from Turkey and to identify factors related to the recurrence of IGM. METHODS: The study was designed as a multicentre retrospective study including 22 breast centres in Turkey...
July 27, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28740962/the-effect-of-corticosteroid-treatment-on-bilateral-idiopathic-granulomatous-mastitis
#6
Fatih Çiftci, İbrahim Abdurrahman, Zeynep Tatar
Idiopathic granulomatous mastitis (IGM) is the commonly encountered form of granulomatous mastitis that may result into repetitive infections and/or abscess formation. Mastitis may develop secondary to a systemic disorder such as tuberculosis, diabetes mellitus, or rheumatoid arthritis, or it may develop as an idiopathic disorder. Idiopathic granulomatous mastitis is the most frequent form of all granulomatous diseases affecting the breast. This disorder frequently presents as painful and fast-growing mass in the breast...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28740959/idiopathic-granulomatous-mastitis-an-institutional-experience
#7
Seetharam Prasad, Padmapriya Jaiprakash, Aniket Dave, Deepti Pai
OBJECTIVE: To study idiopathic granulomatous mastitis with respect to its various clinical features, etiologic factors, treatment modalities and complications. MATERIAL AND METHODS: Retrospective study of all patients who were diagnosed with idiopathic granulomatous mastitis from 1(st) January 2006 to 31(st) December 2014 at Kasturba Hospital, Manipal, India (a tertiary care referral centre). The research was performed according to the World Medical Association Declaration of Helsinki...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28739122/idiopathic-granulomatous-mastitis-a-diagnostic-and-therapeutic-challenge
#8
C M Freeman, B T Xia, G C Wilson, J D Lewis, S Khan, S J Lee, E E Lower, M J Edwards, E A Shaughnessy
BACKGROUND: Idiopathic granulomatous mastitis is a rare benign breast disease of women of reproductive age. It usually presents as a painful mass. Since the etiology is unclear, directed diagnosis and management is lacking. METHODS: This is a retrospective chart review of 14 patients, over twelve years (2004-2016), identified through query of pathology findings. RESULTS: Two asymptomatic patients were diagnosed after oncologic breast resection following neoadjuvant chemotherapy...
July 8, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28733047/idiopathic-granulomatous-mastitis-a-rare-benign-entitiy-that-can-simulate-breast-cancer
#9
Caridad Marín Hernández, Antonio Piñero Madrona, Pedro José Gil Vázquez, Pedro José Galindo Fernández, Pascual Parrilla Paricio
No abstract text is available yet for this article.
July 18, 2017: Cirugía Española
https://www.readbyqxmd.com/read/28731822/treatments-for-idiopathic-granulomatous-mastitis-systematic-review-and-meta-analysis
#10
Xin Lei, Kai Chen, Liling Zhu, Erwei Song, Fengxi Su, Shunrong Li
OBJECTIVES: Idiopathic granulomatous mastitis (IGM) is a benign breast disease with no ideal treatment regimen so far. This study aimed to evaluate the complete remission/resolution (CR) rate and recurrence rate of different treatment options. METHODS: We systematically searched and identified eligible studies from January 1, 2010, to December 31, 2015, in PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Medline databases. We included original studies reporting the CR and/or recurrence rate of each treatment used...
September 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28729183/differentiation-between-idiopathic-granulomatous-mastitis-and-malignant-breast-lesions-using-strain-ratio-on-ultrasonic-elastography
#11
B Yağcı, I Erdem Toslak, B Çekiç, M Öz, B R Karakaş, M Akdemir, S Yıldız, D Süren, D Bova
PURPOSE: The goal of this study was to investigate the strain elastography imaging characteristics of idiopathic granulomatous mastitis (IGM) and compare strain ratio values of IGM with those of breast cancer. MATERIAL AND METHODS: Twenty-three consecutive women with IGM (mean age, 37.9±6.6 [SD] years; range: 26-52 years) and 45 women with malignant breast tumor (mean age, 52.8±12.0 [SD], range, 32-77 years) who had been scheduled for ultrasound-guided core biopsy were recruited to the study...
July 17, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28655119/follow-up-of-granulomatous-mastitis-with-monitoring-versus-surgery
#12
Hasan Çalış, Serif Melih Karabeyoglu
BACKGROUND: IGM (Idiopathic Granulomatous Mastitis) is a rare, chronic, non-malignant and non-life-threatening breast disease. Clinically and radiologically, it has similar characteristics with other granulomatous diseases and breast carcinomas. METHODS: The patients whom diagnosed IGM according to pathology report were retrospectively evaluated between November 2014 and January 2016. The demographic properties, complaints during admission, diagnosis and treatment methods and clinical results were obtained via investigation of the patient files...
June 23, 2017: Breast Disease
https://www.readbyqxmd.com/read/28442140/cystic-neutrophilic-granulomatous-mastitis-associated-with-corynebacterium-including-corynebacterium-kroppenstedtii
#13
Kate J Johnstone, Jennifer Robson, Sarah G Cherian, Jenny Wan Sai Cheong, Kris Kerr, Judith F Bligh
Granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. Once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous mastitis (CNGM). We describe 15 cases with histological features either confirming (n = 12) or suggesting (n = 3) CNGM, and concurrent microbiological evidence of Corynebacterium species. The organism was detected by culture or 16S rRNA gene sequencing of specimens obtained at surgery or fine needle aspiration...
June 2017: Pathology
https://www.readbyqxmd.com/read/28331742/negative-pressure-wound-therapy-in-chronic-inflammatory-breast-diseases
#14
Ozan Barış Namdaroğlu, Hilmi Yazıcı, Ahmet Mücteba Öztürk, Savaş Yakan, Mehmet Yıldırım, Ahmet Deniz Uçar, Nazif Erkan
Mastitis is inflammation of breast tissue that may or may not originate from an infection. Two different forms of mastitis have been described, lactational and non-lactational. Lactational mastitis is the most common type and generally conservative therapy that includes milk removal and physical therapy provides symptomatic relief, but antibiotic therapy is also needed. Common types of non-lactational mastitis are periductal mastitis and idiopathic granulomatous mastitis. Treatment includes antibiotics, drainage, and surgery, but usually this is a chronic process and a therapeutic management algorithm for chronic breast inflammation is unclear and has no consensus...
April 2016: Journal of Breast Health (2013)
https://www.readbyqxmd.com/read/28321344/pituitary-adenoma-and-hyperprolactinemia-accompanied-by-idiopathic-granulomatous-mastitis
#15
Sebahattin Destek, Vahit Onur Gul, Serkan Ahioglu, Kursat Rahmi Serin
Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive use. A 39-year-old patient with no history of oral contraceptive use presented with complaints such as redness, pain, and swelling in her left breast. Ultrasound and magnetic resonance imaging (MRI) revealed a suspicious inflamed mass lesion...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28273980/risperidone-induced-granulomatous-mastitis-secondary-to-hyperprolactinemia-in-a-non-pregnant-woman-a-rare-case-report-in-a-bipolar-disorder
#16
Sadhana Holla, M B Amberkar, Avinash Kamath, Meena Kumari Kamalkishore, Balaji Ommurugan
Idiopathic granulomatous lesion is a rare entity of the breast seen in young-middle aged women. Diagnosis and management of granulomatous lesions with known aetiology does not impose major clinical problems. However, most often these lesions are undetected or unnoticed due to lack of timely diagnosis and inappropriate management, as primarily it is idiopathic. Hyperprolactinemia have been proposed as one of the mechanisms underlying the development of granulomatous lesions of the breast. We report a case of hyperprolactinemia due to risperidone therapy for bipolar mood disorder in a woman who eventually developed granulomatous mastitis...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28271562/erythema-nodosum-in-association-with-idiopathic-granulomatous-mastitis-a-case-series-and-review-of-the-literature
#17
LETTER
R Fruchter, C Castilla, E Ng, M K Pomeranz, A N Femia
No abstract text is available yet for this article.
March 8, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28217653/corticosteroid-and-azithromycin-in-idiopathic-granulomatous-mastitis
#18
Marzieh Salehi, Maryam Salehi, Nader Kalbasi, Atousa Hakamifard, Hassan Salehi, Mohammad Mahdi Salehi, Jalil Sharifian
BACKGROUND: Mastitis is an inflammatory disorder in breast tissues due to bacterial factors, mycobacterial infections or autoimmune diseases. Idiopathic granulomatous mastitis (IGM) is a form of mastitis which may be affected by systematic diseases such as sarcoidosis, and infectious causes such as mycobacterium and fungus. This study evaluates the efficacy of medical therapy with a combination of corticosteroid and Azithromycin in patients with IGM. MATERIALS AND METHODS: This study is a clinical trial research carried out in Alzahra Hospital (Isfahan, Iran) in 2013 on granulomatous mastitis patients...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28188314/firm-non-tender-mass-in-right-breast-%C3%A2-worsening-nonproductive-cough-%C3%A2-pleuritic-pain-%C3%A2-dx
#19
Trang D Lehman, Zubin Damania, Clifford N Tschetter, Norman L Lehman
Granulomatous lesions, such as foreign body granuloma, idiopathic granulomatous mastitis (IGM), and sarcoidosis can mimic breast carcinoma. IGM is associated with elevated prolactin (eg, pregnancy or oral contraceptive use) and is usually subareolar. Infection, however, is also commonly subareolar.
January 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/28050664/rifampicin-for-idiopathic-granulomatous-lobular-mastitis-a-promising-alternative-for-treatment
#20
Omar Farouk, Mohamed Abdelkhalek, Ahmed Abdallah, Ahmed Shata, Ahmed Senbel, Essam Attia, Mohamed Abd Elghaffar, Mahmoud Mesbah, Nermine Soliman, Maha Amin, Dina El-Tantawy
BACKGROUND: Idiopathic granulomatous lobular mastitis (IGLM) is a chronic, non-caseating, inflammatory breast disease of obscure aetiology characterized by multiple masses, abscesses and sinus formation. There is no standard treatment to date, but surgical procedures and systemic corticosteroids are effective in its treatment despite high recurrence rates. PATIENTS AND METHODS: This prospective study including 30 patients with IGLM between November 2012 and May 2016 aimed to investigate the possibility of administration of Rifampicin (300 mg twice daily for a period of 6-9 months) as an alternative therapy for both surgery and corticosteroids in patients with IGLM...
May 2017: World Journal of Surgery
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