Suke Deng, Jiacheng Wang, Yan Hu, Yajie Sun, Xiao Yang, Bin Zhang, Yue Deng, Wenwen Wei, Zhanjie Zhang, Lu Wen, You Qin, Fang Huang, Yuhan Sheng, Chao Wan, Kunyu Yang
Immunotherapy has revolutionized the treatment of cancer. However, its efficacy remains to be optimized. There are at least two major challenges in effectively eradicating cancer cells by immunotherapy. Firstly, cancer cells evade immune cell killing by down-regulating cell surface immune sensors. Secondly, immune cell dysfunction impairs their ability to execute anti-cancer functions. Radiotherapy, one of the cornerstones of cancer treatment, has the potential to enhance the immunogenicity of cancer cells and trigger an anti-tumor immune response...
April 8, 2024: Journal of Nanobiotechnology