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Ethanol ablation

B Liu, J Long, W Wang, G Huang, C Jiang, X Zhang, M Liu, P Liang, J Yu, X Xie, M Kuang
AIM: To evaluate the technical feasibility and treatment results of ultrasound (US)-guided percutaneous radiofrequency ablation (RFA) combined with ethanol ablation (EA) for hepatocellular carcinoma (HCC) in the caudate lobe. MATERIALS AND METHODS: The institutional review board approved this retrospective study and the requirement for informed consent was waived. From October 2009 to June 2016, there were 49 patients with HCC in the caudate lobe underwent ablation...
April 4, 2018: Clinical Radiology
A Ito, T Ebata, Y Yokoyama, T Igami, T Mizuno, J Yamaguchi, S Onoe, M Nagino
BACKGROUND: Only a few reports exist on the use of ethanol ablation for posthepatectomy bile leakage. The aim of this study was to assess the value of ethanol ablation in refractory bile leakage. METHODS: Medical records of consecutive patients who underwent a first hepatobiliary resection with bilioenteric anastomosis between 2007 and 2016 were reviewed retrospectively, with special attention to bile leakage and ethanol ablation therapy. Bile leakage was graded as A/B1/B2 according to the International Study Group of Liver Surgery definition...
April 4, 2018: British Journal of Surgery
Ahmed Eissa, Ahmed El Sherbiny, Eugenio Martorana, Giacomo M Pirola, Stefano Puliatti, Michele Scialpi, Salvatore Micali, Bernardo Rocco, Evangelos Liatsikos, Alberto Breda, Francesco Porpiglia, Giampaolo Bianchi
INTRODUCTION: Renal cysts are common findings in nearly 10% of general population. According to Bosniak classification, they are classified into simple and complex renal cysts based on their CT characteristics. The majority of simple renal cysts are asymptomatic and require no intervention. Once they become symptomatic or complicated, a non-conservative management should be considered. EVIDENCE ACQUISITION: This paper is a narrative review of existing manuscripts regarding the non-conservative management of renal cysts...
April 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Shuling Chen, Zhenwei Peng, Manxia Lin, Zebin Chen, Wenjie Hu, Xiaoyan Xie, LongZhong Liu, Guojun Qian, Baogang Peng, Bin Li, Ming Kuang
OBJECTIVES: To compare combined percutaneous radiofrequency ablation and ethanol injection (RFA-PEI) with hepatic resection (HR) in the treatment of resectable solitary hepatocellular carcinoma (HCC) with 2.1-5.0 cm diameter. METHODS: From June 2009 to December 2015, 271 patients whom underwent RFA-PEI (n = 141) or HR (n = 130) in three centres were enrolled. The overall survival (OS) and recurrence-free survival (RFS) between groups were compared with Kaplan-Meier method and log-rank tests...
March 29, 2018: European Radiology
Naveen Kalra, Mandeep Kang, Ajay K Duseja, Anmol Bhatia, Virendra Singh, Radha K Dhiman, Arvind Rajwanshi, Yogesh K Chawla, Niranjan Khandelwal
Background & objective: It has been shown that the combined use of alcohol before radiofrequency ablation (RFA) helps to augment the therapeutic advantage of RFA. The present study was conducted to compare the outcome of treatment with RFA alone and RFA with alcohol as ablative technique in patients with small hepatocellular carcinomas (HCCs), who were not candidates for surgery. Methods: Fifty patients with chronic liver disease and concurrent HCC were enrolled in this prospective study...
November 2017: Indian Journal of Medical Research
Jun-Ho Choi, Do Hyun Park, Myung-Hwan Kim, Hee Sang Hwang, Seung-Mo Hong, Tae Jun Song, Sang Soo Lee, Dong-Wan Seo, Sung Koo Lee
OBJECTIVES: Little is known about the standard care of small (less than 2 cm in diameter) pancreatic neuroendocrine tumors (PNETs). The aim of this study was to determine the clinical outcomes of small PNETs after endoscopic ultrasound (EUS)-guided ethanol-lipiodol ablation (EUS-ELA). METHODS: In this prospective cohort study, consecutive patients who underwent EUS-ELA for PNETs were enrolled and were followed for ≥ 3 years. Treatment efficacy was the primary outcome measure...
March 25, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Niusha Lasemi, Oscar Bomati Miguel, Ruth Lahoz, Vassili Lennikov, Ulrich Pacher, Christian Rentenberger, Wolfgang Kautek
Homogeneous polycrystalline FexOy nanoparticles were generated by ablation of iron targets in water by nanosecond laser pulses at 532 nm. In ethanol, crystalline core-shell Fe/FexOy structures with size medians around 20 nm were produced. The ablation of FeWxOy targets in water resulted in crystalline hollow shells and homogeneous FeWxOy nanoparticles. In contrast, amorphous core-shell FeWxOy nanoparticles with a median size of 17 nm were produced in ethanol. The size distribution of both the FexOy and the FeWxOy particles showed a slight dependence on fluence and pulse number...
March 15, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
Jin Ho Choi, Sang Hyub Lee, Young Hoon Choi, Jinwoo Kang, Woo Hyun Paik, Dong-Won Ahn, Ji Kon Ryu, Yong-Tae Kim
Background: Endoscopic ultrasound-guided ethanol ablation (EUS-EA) is a recently introduced treatment for pancreatic cystic lesions (PCLs). However, clinical benefits such as survival gain and maintenance of quality of life (QOL) have not been fully established. The aim of this study was to evaluate the clinical benefits of EUS-EA compared with the natural course (NC) of PCLs. Methods: This retrospective comparative study of patients with PCLs investigated an EUS-EA group ( n = 118) and an NC group ( n = 428)...
2018: Therapeutic Advances in Gastroenterology
C Rubod, E Jean Dit Gautier, C Yazbeck
Surgical management of ovarian endometrioma is most often part of a global approach of endometriosis pathology. Isolated endometrioma are rare. Laparoscopic cystectomy is the gold standard for surgical management of endometrioma. Nevertheless, this technique impacts the ovarian function. The hemostasis of the ovarian cyst bed should be performed to conserve the ovarian stroma. Ultrasonography-guided cyst aspiration, laparoscopic drainage and simple bipolar coagulation are not recommended as first line of treatment...
March 3, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
Francisca Vaz Bravo, Jorge Da Silva, Robin Barry Chan, Gilbert Di Paolo, Andreia Teixeira-Castro, Tiago Gil Oliveira
Phospholipase D (PLD) is a key player in the modulation of multiple aspects of cell physiology and has been proposed as a therapeutic target for Alzheimer's disease (AD). Here, we characterize a PLD mutant, pld-1, using the Caenorhabditis elegans animal model. We show that pld-1 animals present decreased phosphatidic acid levels, that PLD is the only source of total PLD activity and that pld-1 animals are more sensitive to the acute effects of ethanol. We further show that PLD is not essential for survival or for the normal performance in a battery of behavioral tests...
February 23, 2018: Scientific Reports
Marco Calandri, Carlo Gazzera, Steven Yevich, Katia Lapenna, Maria Marenco, Andrea Veltri, Gianluca Paraluppi, Paolo Fonio
BACKGROUND: To evaluate the safety and efficacy of percutaneous ablation for HCC hepatic recurrence along surgical resection margins to achieve complete cure or bridge for additional treatment. No current recommendations exist for these lesions. METHODS: Retrospective review of post-surgical recurrent HCC located along surgical margins treated by percutaneous ultrasound-guided ablation from 2006-2014. Ablation was performed by radiofrequency ablation (RFA) or percutaneous ethanol injection (PEI), selected for recurrence in proximity to extrahepatic organs...
February 21, 2018: Minerva Chirurgica
(no author information available yet)
No abstract text is available yet for this article.
February 19, 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
M A Gondal, T A Fasasi, Umair Baig, A Mekki
In this work, pulsed laser ablation in liquid (PLAL) technique was applied to synthesize colloidal nanoparticles of zirconium oxide (ZrO2) in three different aqueous media (de-ionized water, ethanol and acetone). The structure, morphology, composition and optical properties of the synthesized nanoparticles were characterized by XRD, SEM, TEM, XPS, UV-Vis spectrophotometer and FT-IR analysis respectively. The structural analysis by XRD reveals the formation of mixture of monoclinic and tetragonal phases of nanocrystalline zirconia...
June 1, 2018: Journal of Nanoscience and Nanotechnology
Emma Burch, Lacey Lubeley, James Murakami
Objectives: Sialorrhea is a common health and psychosocial problem for children with neuromuscular dysfunction secondary to a variety of disorders such as cerebral palsy. Current accepted treatments include the injection of botulinum toxin into the submandibular glands for temporary symptom relief. The purpose of this study is to demonstrate the feasibility of percutaneous ethanol injection for longer lasting salivary gland ablation in an animal model. Material and Methods: Twenty rats were used in this study...
October 2017: Journal of Oral & Maxillofacial Research
Sora Choi, Afua A Gyamfi, Prince Neequaye, Samuel Addo, Frank J Gonzalez, Maxwell A Gyamfi
The pregnane X receptor (PXR, NR1I2) is a xenobiotic-sensing nuclear receptor that defends against toxic agents. We have shown that PXR promotes chronic ethanol (EtOH)-induced steatosis. Therefore, we examined the role of PXR in binge EtOH-induced hepatotoxicity. Male wild type (WT) and Pxr-null mice were orally administered three binge doses of EtOH (4.5 g/kg, every 12 hours) and euthanized four hours after the final dose. Pxr-null mice displayed higher basal mRNA levels of hepatic lipogenic transcription factor sterol regulatory element binding protein 1c (Srebp-1c) and its target stearoyl-CoA desaturase 1 (Scd1) and the lipid peroxide detoxifying aldo-keto reductase 1b7 (Akr1b7) and higher protein levels of EtOH-metabolizing alcohol dehydrogenase 1 (ADH1)...
February 5, 2018: Journal of Pharmacology and Experimental Therapeutics
Naiem Nassiri, Lauren A Huntress, Mitchell Simon, Susan Murphy
OBJECTIVE: No standardized therapeutic algorithm or embolic agent of choice has yet been identified for management of congenital peripheral venous malformations (VMs). Treatment options and reported outcomes therefore vary widely. Herein, we present an institution-wide algorithm for management of symptomatic congenital peripheral VMs using a single embolotherapeutic modality. METHODS: During 36 months, patients with symptomatic congenital peripheral VMs underwent contrast-enhanced magnetic resonance imaging...
January 29, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Baoxian Liu, Chunlin Jiang, Shuling Chen, Guangliang Huang, Yu Wang, Jiaping Li, Ming Xu, Xiaoyan Xie, Ming Kuang
PURPOSE: To retrospectively investigate the efficacy of multipronged ethanol ablation with or without transarterial chemoembolization (TACE) in the treatment of intermediate hepatocellular carcinoma (HCC) (3.1-5.0 cm in diameter) at high-risk locations . MATERIAL AND METHODS: From March 2009 to April 2014, 25 consecutive patients with intermediate HCC who underwent multipronged ethanol ablation combined with TACE were included in the combination treatment group, while 50 patients who underwent multipronged ethanol ablation alone were included in the control group...
February 1, 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
Sang Hyub Lee
The decision of the appropriate treatment for pancreatic cystic lesions (PCLs) is becoming increasingly important as the number of incidentally found PCLs increases. A range of modalities have been attempted because there has been an increasing demand for minimally invasive treatment for PCLs due to the large burden of a surgical resection. Endoscopic treatment using endoscopic ultrasonography (EUS), a representative of minimally invasive therapy, can be categorized into two types: ablation therapy by the injection of drugs and topical thermal coagulative therapy through the high topical energy...
January 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
Chan Park, Chong Hyun Suh, Ji Eun Shin, Jung Hwan Baek
BACKGROUND: Understanding the characteristics of the middle cervical sympathetic ganglion (MCSG) may minimize procedure-related complications and maximize efficacy during surgery or ultrasound (US)-guided procedures. The location and detection rate of the MCSG were variable in small population studies. Therefore, a large population study or meta-analysis could give more information about the MCSG. OBJECTIVES: We aim to review the published literature and evaluate the anatomical features of the MCSG, including the detection rate, location, size, and a normal variation, and to review the clinical relevance of MCSG for procedures including, US-guided ganglion block, ethanol ablation (EA), or radiofrequency ablation (RFA)...
January 2018: Pain Physician
C X Ge, M Z Tai, T Chen, K L Li, Z P Qin
Objective: To analyze the clinical data and summarize therapeutic experiences of cervicofacial venous malformations involving isthmus faucium area. Methods: Clinical records from 143 patients with venous malformations involving isthmus faucium area treated at our hospital between January 2012 and January 2016 were reviewed. There were 70 males and 73 females. Age ranged from 1 to 52 years old, with a median age of 14.5 years. There were 19 cases with lesions involving in only 1 subanatomic area above and 124 cases with lesions involving in more than 1 subanatomic areas, including 63 cases with lesions involving in more than 2 areas...
December 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
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