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Ethanol ablation

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https://www.readbyqxmd.com/read/29023719/natural-variability-and-effects-of-cleaning-and-storage-procedures-on-vertebral-chemistry-of-the-blacktip-shark-carcharhinus-limbatus
#1
J P Lewis, W F Patterson, J K Carlson
Key methodological assumptions regarding the degree of natural variability and influence of sample handling and storage of elasmobranch vertebral chemistry were assessed using laser-ablation inductively coupled plasma mass spectrometry. Vertebral chemistry of juvenile blacktip sharks Carcharhinus limbatus was examined to identify whether differences existed among different regions of the vertebral column, between thoracic vertebrae of individual fish or within individual vertebrae. Additionally, the effects of bleach exposure and storage in ethanol on vertebral chemistry were compared...
October 10, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28974113/combined-radiofrequency-ablation-and-ethanol-injection-versus-repeat-hepatectomy-for-elderly-patients-with-recurrent-hepatocellular-carcinoma-after-initial-hepatic-surgery
#2
Shuling Chen, Zhenwei Peng, Han Xiao, Manxia Lin, Zebin Chen, Chunlin Jiang, Wenjie Hu, Xiaoyan Xie, Longzhong Liu, Baogang Peng, Ming Kuang
PURPOSE: To retrospectively compare the efficacy and safety of combined radiofrequency ablation and percutaneous ethanol injection (RFA-PEI) with repeat hepatectomy for elderly patients with initial recurrent hepatocellular carcinoma (HCC) after hepatic surgery. METHODS: From January 2009 to June 2015, 105 elderly patients (≥ 70 years) who underwent RFA-PEI (n = 57) or repeated hepatectomy (n = 48) for recurrent HCC ≤ 5.0 cm were included in the study...
October 4, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28970243/efficacy-and-safety-of-ethanol-ablation-for-branchial-cleft-cysts
#3
E J Ha, S M Baek, J H Baek, S Y Shin, M Han, C-H Kim
BACKGROUND AND PURPOSE: Branchial cleft cyst is a common congenital lesion of the neck. This study evaluated the efficacy and safety of ethanol ablation as an alternative treatment to surgery for branchial cleft cyst. MATERIALS AND METHODS: Between September 2006 and October 2016, ethanol ablation was performed in 22 patients who refused an operation for a second branchial cleft cyst. After the exclusion of 2 patients who were lost to follow-up, the data of 20 patients were retrospectively evaluated...
September 28, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28944178/alcohol-septal-ablation-in-which-patients-and-why
#4
Paolo Spirito, Jessica Rossi, Barry J Maron
At present, surgical septal myectomy is regarded as the "gold standard" treatment for most patients with obstructive hypertrophic cardiomyopathy (HCM) and drug-refractory symptoms. However, the best results are obtained by those surgeons who have extensive experience with this operation at a small number of referral centers. In the mid-1990s, percutaneous alcohol septal ablation was introduced as an alternative to myectomy to reduce LV outflow gradient and heart failure symptoms in patients with obstructive HCM...
July 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28940897/effects-of-sample-cleaning-and-storage-on-the-elemental-composition-of-shark-vertebrae
#5
John A Mohan, Thomas C TinHan, Nathan R Miller, R J David Wells
RATIONALE: Application of vertebral chemistry in elasmobranchs has the potential to progress our understanding of individual migration patterns and population dynamics. However, the influence of handling artifacts such as sample cleaning and storage on vertebral chemistry is unclear and requires experimental investigation. METHODS: Vertebrae centra from blacktip sharks (Carcharhinus limbatus) were cleaned with bleach (NaOCl) for five minutes (m), 1 hour (h) and 24 (h) in a cleaning experiment and stored frozen, in 70% ethanol, and 10% formalin treatments for 20 days in a storage experiment...
September 20, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28926900/-the-combination-of-percutaneous-iohexol-ethanol-injection-with-radiofrequency-ablation-for-the-treatment-of-primary-liver-cancer-in-high-risk-locations
#6
W Sun, X Y Ding, J L Chen, W D Li, X Y Wang, X D Guo, Y J Shen, S S Sun
Objective: To investigate the safety and efficacy of radiofrequency ablation (RFA) with percutaneous iohexol-ethanol injection (PIEI), compared with RFA plus transcatheter arterial chemoembolization (TACE) for patients with primary liver cancer(PLC)in high-risk locations. Methods: From January 2012 to December 2014, 54 patients with PLC in high-risk locations were enrolled. They were divided into Group A (RFA combined with PIEI) and Group B (RFA plus TACE). The efficacy and adverse events were assessed. Results: 54 patients had 74 lesions in high-risk locations...
September 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28821832/development-of-enhanced-ethanol-ablation-as-an-alternative-to-surgery-in-treatment-of-superficial-solid-tumors
#7
Robert Morhard, Corrine Nief, Carlos Barrero Castedo, Fangyao Hu, Megan Madonna, Jenna L Mueller, Mark W Dewhirst, David F Katz, Nirmala Ramanujam
While surgery is at the foundation of cancer treatment, its access is limited in low-income countries. Here, we describe development of a low-cost alternative therapy based on intratumoral ethanol injection suitable for resource-limited settings. Although ethanol-based tumor ablation is successful in treating hepatocellular carcinomas, the necessity for multiple treatments, injection of large fluid volumes, and decreased efficacy in treatment of non-capsulated tumors limit its applicability. To address these limitations, we investigated an enhanced ethanol ablation strategy to retain ethanol within the tumor through the addition of ethyl cellulose...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819950/successful-eus-guided-ethanol-ablation-of-insulinoma-four-year-follow-up-case-report-and-literature-review
#8
Krzysztof Dąbkowski, Paula Gajewska, Kamila Walter, Magdalena Londzin-Olesik, Andrzej Białek, Elżbieta Andrysiak-Mammos, Beata Kos-Kudła, Teresa Starzyńska
INTRODUCTION: EUS-guided ethanol ablation of insulinoma is a new method of treatment of this neuroendocrine tumour. Ablation is recommended in patients who are poor surgical candidates or refuse surgery. We present a case of an 81-year-old female with symptomatic insulinoma, treated successfully with EUS-guided alcoholic ablation, along with a literature review including 28 other previously described cases. The effectiveness, safety of the therapy, and technical procedure-related issues are summarised...
2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28802565/the-safety-and-efficacy-of-an-alcohol-free-pancreatic-cyst-ablation-protocol
#9
Matthew T Moyer, Setareh Sharzehi, Abraham Mathew, John M Levenick, Brandy D Headlee, Jonathan T Blandford, Heather D Heisey, James H Birkholz, Brooke B Ancrile, Jennifer L Maranki, Niraj J Gusani, Thomas J McGarrity, Charles E Dye
BACKGROUND & AIMS: Endoscopic ultrasound (EUS)-guided chemoablation with ethanol lavage followed by infusion of paclitaxel is effective for the treatment of mucinous pancreatic cysts. However, complications arise in 3%-10% of patients, presumably linked to the inflammatory effects of ethanol. We aimed to determine whether alcohol is required for effective pancreatic cyst ablation, if removing alcohol from the ablation process would improve complication rates, and whether a multi-agent chemotherapeutic cocktail could increase the rate of complete cyst resolution compared with findings reported from previous trials using alcohol followed by paclitaxel alone...
August 9, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28797186/ethanol-and-thermal-ablation-for-malignant-thyroid-tumours
#10
So Yeong Jeong, Jung Hwan Baek, Young Jun Choi, Jeong Hyun Lee
Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid malignancy and has a good prognosis and low mortality rate. Surgery is the standard treatment for patients with primary and recurrent thyroid cancer. Although patients with PTC usually exhibit excellent treatment outcome, the incidence of recurrence in the neck ranges from 20% to 59%. When a patient with thyroid cancer is contraindicated for surgery, ultrasound (US)-guided ablation techniques, including ethanol ablation (EA) and thermal ablations, are suggested alternatives...
August 11, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28795996/initial-alpha-fetoprotein-response-predicts-prognosis-in-hepatitis-b-related-solitary-hcc-patients-after-radiofrequency-ablation
#11
Su Jong Yu, Jee Hye Kwon, Won Kim, Jung-Hwan Yoon, Jeong Min Lee, Jae Young Lee, Eun Ju Cho, Jeong-Hoon Lee, Hwi Young Kim, Yong Jin Jung, Yoon Jun Kim
BACKGROUND: Radiofrequency ablation (RFA) is effective for early-stage hepatocellular carcinoma but recurrence is problem. GOALS: To identify prognostic factors including alpha-fetoprotein (AFP) for overall survival and intrahepatic recurrence after RFA. PATIENTS AND METHODS: Not only naïve but also previously treated patients with solitary hepatitis B virus-related hepatocellular carcinoma <5 cm were prospectively enrolled and a ≥50% decrease from baseline to 1 month after RFA was defined as an initial AFP response...
August 8, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28755102/non-surgical-ablative-therapies-for-inoperable-benign-insulinoma
#12
REVIEW
C Mele, A Brunani, B Damascelli, V Tichà, L Castello, G Aimaretti, M Scacchi, P Marzullo
PURPOSE: Benign insulinoma is the most common functioning neuroendocrine tumor of the pancreas. The gold-standard therapeutic approach for insulinoma is surgery, which allows for tumor removal, histology and immunochemical analyses. If surgery is not feasible, minimally invasive ablative procedures performed by interventional radiology can lead to partial or complete remission of hormone hypersecretion and tumor control in insulinoma patients. METHODS: We performed a review of existing literature on non-chemotherapeutic/radioactive ablative techniques employed for the treatment of benign, otherwise inoperable, pancreatic insulinoma...
July 28, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28718950/radiofrequency-ablation-for-the-management-of-thyroid-nodules-a-critical-appraisal-of-the-literature
#13
REVIEW
Roberto Cesareo, Andrea Palermo, Valerio Pasqualini, Roberto Cianni, Gianluigi Gaspa, Silvia Manfrini, Claudio Maurizio Pacella
The majority of benign thyroid nodules are asymptomatic, remain stable in size and do not require treatment. However, a minority of patients with growing nodules may have local symptoms or cosmetic concerns, and thus demand surgical therapy. The timely use of ultrasound-guided, minimally invasive thermal therapies has changed the natural history of benign, enlarging thyroid nodules (TNs). These procedures produce persistent shrinkage of TNs and an improvement of local symptoms. Among the various procedures, percutaneous ethanol injection represents the first-line treatment for thyroid cysts, while in solid cold nodules, laser and radiofrequency ablation (RFA) have proven to be very effective and safe techniques in producing significant volume reduction that remains stable over several years...
July 18, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28693505/effects-of-radiofrequency-ablation-versus-other-ablating-techniques-on-hepatocellular-carcinomas-a-systematic-review-and-meta-analysis
#14
Wen Luo, Yunfei Zhang, Guangbin He, Ming Yu, Minjuan Zheng, Liwen Liu, Xiaodong Zhou
BACKGROUND: Percutaneous ablation has quickly arisen as one of the important alternative treatments for hepatocellular carcinoma (HCC). We aimed to compare the therapeutic effects of radiofrequency ablation (RFA) and other ablative techniques on HCCs. METHODS: Databases were searched to identify literature on complete tumor ablation (CTA), overall survival (OS), local tumor recurrence (LTR), and complications of RFA in the treatment of HCC, compared with those of microwave ablation (MWA), percutaneous ethanol injection (PEI), PEI plus RFA, cryoablation (CRA), laser ablation (LSA), and high-intensity focused ultrasound...
July 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28663262/ethanol-ablation-of-ranulas-short-term-follow-up-results-and-clinicoradiologic-factors-for-successful-outcome
#15
K H Ryu, J H Lee, J Y Lee, S R Chung, M S Chung, H W Kim, Y J Choi, J H Baek
BACKGROUND AND PURPOSE: Surgical excision of an affected sublingual gland for treatment of a ranula can carry a potential of a nerve damage or postoperative complications. However, there have been little studies about effective minimally invasive therapeutic method, yet. Our aim was to evaluate the efficacy and safety of ethanol ablation of ranulas and the clinicoradiologic factors that can predict outcome. MATERIALS AND METHODS: This retrospective study evaluated 23 patients with ranulas treated by percutaneous ethanol ablation...
June 29, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28628747/laser-ablation-of-silver-in-liquid-organic-monomer-influence-of-experimental-parameters-on-the-synthesized-silver-nanoparticles-graphite-colloids
#16
Maxime Delmée, Grégory Mertz, Julien Bardon, Adeline Marguier, Lydie Ploux, Vincent Roucoules, David Ruch
During the past decade, synthesizing silver nanoparticles (Ag NPs) by liquid phase-pulsed laser ablation (LP-PLA) has attracted a lot of attention. Basically, this technique allows producing various metallic nanoparticles with controlled size, shape, composition, or surroundings in several liquids (i.e., water, ethanol, acetone, toluene, and so forth). Recently, such processes have been studied in liquid organic monomer such as methyl methacrylate (MMA). However, the influence of the laser parameters on the materials synthesized in such reactive liquid and their features were not fully investigated so far...
July 3, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28589088/a-2016-italian-survey-about-guidelines-and-clinical-management-of-thyroid-nodules
#17
Roberto Negro, Roberto Attanasio, Franco Grimaldi, Andrea Frasoldati, Rinaldo Guglielmi, Enrico Papini
BACKGROUND: While thyroid nodules are frequent in endocrine clinical practice, patients are often asymptomatic and euthyroid, and death is rare in cases of malignancy. OBJECTIVES: To evaluate the perception of current international guidelines regarding thyroid nodule management among Italian endocrinologists, and to compare daily clinical practice with suggested recommendations. METHODS: Italian Association of Clinical Endocrinologists (AME) members were invited to participate in a Web-based survey...
April 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/28511236/long-term-outcomes-after-endoscopic-ultrasound-guided-ablation-of-pancreatic-cysts
#18
Jun-Ho Choi, Dong Wan Seo, Tae Jun Song, Do Hyun Park, Sang Soo Lee, Sung Koo Lee, Myung-Hwan Kim
Background and study aims The aim of this study was to investigate the long-term outcomes after endoscopic ultrasound (EUS)-guided pancreatic cyst ablation. Patients and methods In a single-center, prospective study, 164 patients with pancreatic cysts underwent EUS-guided cyst ablation using ethanol with paclitaxel. The inclusion criteria were as follows: unilocular or oligolocular cysts; clinically indeterminate cysts that required EUS fine-needle aspiration; and/or cysts that grew during the observation period...
September 2017: Endoscopy
https://www.readbyqxmd.com/read/28490991/other-non-surgical-treatments-for-liver-cancer
#19
Paul Revel-Mouroz, Philippe Otal, Marion Jaffro, Antoine Petermann, Olivier Meyrignac, Pierre Rabinel, Fatima-Zohra Mokrane
Interventional radiology plays a major role in the modern management of liver cancers, in primary hepatic malignancies or metastases and in palliative or curative situations. Radiological treatments are divided in two categories based on their approach: endovascular treatment and direct transcapsular access. Endovascular treatments include mainly three applications: transarterial chemoembolization (TACE), transarterial radioembolization (TARE) and portal vein embolization (PVE). TACE and TARE share an endovascular arterial approach, consisting of a selective catheterization of the hepatic artery or its branches...
March 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/28458908/endoscopic-ultrasound-guided-ethanol-ablation-therapy-for-pancreatic-insulinoma-an-unusual-strategy
#20
Adriana de Sousa Lages, Isabel Paiva, Patrícia Oliveira, Francisco Portela, Francisco Carrilho
SUMMARY: Insulinomas are the most frequent cause of hyperinsulinaemic hypoglycaemia. Although surgical enucleation is the standard treatment, a few other options are available to high-risk patients who are elderly or present with co-morbidities. We present a case report of an 89-year-old female patient who was admitted to the emergency department due to recurrent hypoglycaemia, especially during fasting. Laboratory work-up raised the suspicion of hyperinsulinaemic hypoglycaemia, and abdominal CT scan revealed a 12 mm nodular hypervascular lesion of the pancreatic body suggestive of neuroendocrine tumour...
2017: Endocrinology, Diabetes & Metabolism Case Reports
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