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https://www.readbyqxmd.com/read/29149797/findings-from-a-strength-based-moderate-intensity-exercise-interventions-for-individuals-with-dementia-innovative-practice
#1
Nicole Dawson, Hayden Gerhart, Katherine S Judge
Limited evidence exists regarding exercise interventions with individuals with dementia, which is often due to heterogeneity of methodology and outcomes being assessed. This led to the development and evaluation of a moderate-intensity home-based functional exercise program guided by theories from exercise science and the Strength-Based Approach. Data indicated excellent treatment adherence (99.04%) along with high levels of acceptability and feasibility in this sample (age 76.63 years (9.84); Mini Mental State Exam 18...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29149791/the-dementia-care-coordination-program-engaging-health-systems-in-caregiver-supports
#2
Pamela Nadash, Nina M Silverstein, Frank Porell
This paper reports on a process evaluation using mixed methods to assess a Dementia Care Coordination Program, which is distinctive in using the medical system, rather than direct outreach, to identify and refer families to supports provided by an Alzheimer's Association chapter via dedicated care consultants. One care consultant received referrals from individual physicians, while the other, employed by a health plan, received referrals from health plan case managers. Through key informant interviews, focus groups, and physician and caregiver surveys, we identified key issues, finding high rates of stakeholder satisfaction, but some practical issues around information sharing and data tracking...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29149772/natural-history-of-infantile-onset-spinal-muscular-atrophy
#3
Stephen J Kolb, Christopher S Coffey, Jon W Yankey, Kristin Krosschell, W David Arnold, Seward B Rutkove, Kathryn J Swoboda, Sandra P Reyna, Ai Sakonju, Basil T Darras, Richard Shell, Nancy Kuntz, Diana Castro, Julie Parsons, Anne M Connolly, Claudia A Chiriboga, Craig McDonald, W Bryan Burnette, Klaus Werner, Mathula Thangarajh, Perry B Shieh, Erika Finanger, Merit E Cudkowicz, Michelle M McGovern, D Elizabeth McNeil, Richard Finkel, Susan T Iannaccone, Edward Kaye, Allison Kingsley, Samantha R Renusch, Vicki L McGovern, Xueqian Wang, Phillip G Zaworski, Thomas W Prior, Arthur H M Burghes, Amy Bartlett, John T Kissel
OBJECTIVE: Infantile-onset spinal muscular atrophy (SMA) is the most common genetic cause of infant mortality, typically resulting in death prior to age 2. Clinical trials in this population require an understanding of disease progression and identification of meaningful biomarkers to hasten therapeutic development and predict outcomes. METHODS: A longitudinal, multi-center, prospective natural history study enrolled 26 SMA infants, and 27 control infants less than six months of age...
November 17, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29149677/effects-of-deslorelin-implants-on-reproduction-and-feeding-behavior-in-tasmanian-devils-sarcophilus-harrisii-housed-in-free-range-enclosures
#4
Holly R Cope, Carolyn J Hogg, Karen Fagg, Olivia Barnard, Peter J White, Catherine A Herbert
In captive breeding programs, it is becoming increasingly important to maximize the retention of genetic diversity by managing the reproductive contribution of each individual, which can be facilitated through the use of selective contraception. This becomes critical when captive populations are held for several generations, and managers must prevent the confines of housing space and financial support from compromising genetic integrity. For example, the Tasmanian devil insurance population, established in 2006, is strategically managed to equalize founder representation...
November 4, 2017: Theriogenology
https://www.readbyqxmd.com/read/29149635/the-association-between-adolescent-cannabis-use-and-anxiety-a-parallel-process-analysis
#5
Jacqueline Duperrouzel, Samuel W Hawes, Catalina Lopez-Quintero, Ileana Pacheco-Colón, Jonathan Comer, Raul Gonzalez
INTRODUCTION: Associations between anxiety symptoms and cannabis use have been previously explored, yet the directionality of these associations remains highly debatable. The present study aims to prospectively examine patterns of cannabis use and anxiety during adolescence focusing on their co-development and bidirectional influences. METHODS: Adolescents (n=250) of predominantly Hispanic ethnicity, aged 14-17 at baseline, exposed to drugs, alcohol, or cigarettes completed three (bi-annual) assessments across a 1-year period...
November 4, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29149155/lower-cutoffs-for-lc-ms-ms-urine-drug-testing-indicates-better-patient-compliance
#6
Kevin Krock, Amadeo Pesce, Dennis Ritz, Richard Thomas, Agnes Cua, Ryan Rogers, Phil Lipnick, Kristen Kilbourn
BACKGROUND: Urine drug testing is used by health care providers to determine a patient's compliance to their prescribed regimen and to detect non-prescribed medications and illicit drugs. However, the cutoff levels used by clinical labs are often arbitrarily set and may not reflect the urine drug concentrations of compliant patients. OBJECTIVES: Our aim was to test the hypothesis that commonly used cutoffs for many prescribed and illicit drugs were set too high, and methods using these cutoffs may yield a considerable number of false-negative results...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29149133/computer-based-exercise-program-effects-of-a-12-week-intervention-on-mood-and-fatigue-in-pediatric-patients-with-cancer%C3%A2
#7
Anna-Maria Platschek, Laura Kehe, Vera Abeln, Frank Berthold, Thorsten Simon, Heiko Strüder
BACKGROUND: Increasing rates of survival present a new set of physical and psychological challenges for children dealing with side effects during cancer treatment. Physical activity has been shown to be an effective strategy to reduce several side effects.
. OBJECTIVES: The purpose of this pilot study was to determine the benefits of a 12-week computer-based exercise intervention on perceived physical, motivational, and fatigue syndrome and psychological state...
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29149129/oncology-nurse-generalist-competencies-oncology-nursing-society-s-initiative-to-establish-best-practice
#8
Michele E Gaguski, Kim George, Susan D Bruce, Edie Brucker, Carol Leija, Kristine LeFebvre, Heather Mackey
BACKGROUND: A project team was formulated to create evidence-based oncology nurse generalist competencies (ONGCs) to establish best practices in competency development, including high-risk tasks, critical thinking criteria, and measurement of key areas for oncology nurses.
. OBJECTIVES: This article aims to describe the process and the development of ONGCs. 
. METHODS: This article explains how the ONGCs were accomplished, and includes outcomes and suggestions for use in clinical practice...
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29149064/who-participates-in-the-great-shakeout-why-audience-segmentation-is-the-future-of-disaster-preparedness-campaigns
#9
Rachel M Adams, Beth Karlin, David P Eisenman, Johanna Blakley, Deborah Glik
Background: In 2008, the Southern California Earthquake Center in collaboration with the U.S. Geological Survey Earthquake Hazards Program launched the first annual Great ShakeOut, the largest earthquake preparedness drill in the history of the United States. Materials and Methods: We collected online survey data from 2052 campaign registrants to assess how people participated, whether audience segments shared behavioral patterns, and whether these segments were associated with five social cognitive factors targeted by the ShakeOut campaign...
November 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29148965/nonclinical-safety-assessment-of-anti-factor-d-key-strategies-and-challenges-for-the-nonclinical-development-of-intravitreal-biologics
#10
Vladimir Bantseev, Rebecca Erickson, Douglas Leipold, Caroline Amaya, Paul E Miller, Helen Booler, Evan A Thackaberry
PURPOSE: The nonclinical toxicology program described here was designed to characterize the safety profile of anti-factor D (AFD; FCFD4514S, lampalizumab) to support intravitreal (ITV) administration in patients with geographic atrophy (GA). METHODS: The toxicity of AFD was assessed in a single-dose and 6-month repeat-dose study in monkeys at doses up to 10 mg/eye. Toxicity was assessed by clinical ophthalmic examinations, intraocular pressure measurements, ocular photography, electroretinography, fluorescein angiography, optical coherence tomography, and anatomic pathology...
November 17, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29148855/effects-of-virtual-reality-based-training-with-bts-nirvana-on-functional-recovery-in-stroke-patients-preliminary-considerations
#11
Rosaria De Luca, Margherita Russo, Antonino Naro, Provvidenza Tomasello, Simona Leonardi, Floriana Santamaria, Latella Desireè, Alessia Bramanti, Giuseppe Silvestri, Placido Bramanti, Rocco Salvatore Calabrò
AIM OF THE STUDY: cognitive impairment occurs frequently in post-stroke patients. This study aimed to determine the effects of a virtual reality training (VRT) with BTs-Nirvana (BTsN) on the recovery of cognitive functions in stroke patients, using the Interactive-Semi-Immersive Program (I-SIP). MATERIALS AND METHODS: We enrolled 12 subjects (randomly divided into two groups: experimental group -EG; and control group -CG), who attended the Laboratory of Robotic and Cognitive Rehabilitation of IRCCS Neurolesi of Messina from January to June 2016...
November 17, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29148633/clinical-assessment-of-cardiovascular-disease-associated-risk-factors-in-jimmatown-southwest-ethiopia-a-community-based-cross-%C3%A2-sectional-study
#12
Hailemichael Desalegn, Sintayehu Fekadu, Amare Deribew
Introduction: Cardiovascular disease has been identified as emerging epidemic in developing world and Sub-saharan Africa. The prevalence of risk factors associated with cardiovascular disease is not clearly established in our country. We conducted this study to determine the prevalence of cardiovascular disease associated risk factors in Jimma town. Methods: A cross-sectional study was conducted in sampled adults in Jimma town. Multi-stage sampling was used by combining simple random sampling to select kebeles of Jimma town and then systematic random sampling to select the house hold ...
January 2017: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/29148615/farmers-perspective-on-herbicide-resistant-weeds-and-application-of-resistance-management-strategies-results-from-a-german-survey
#13
Lena Ulber, Dagmar Rissel
BACKGROUND: A herbicide resistance survey was conducted in Germany to determine farmers' awareness of herbicide resistance and experience with resistant weeds, the used information sources on herbicide resistance and methods employed to confirm resistance. In addition, the application pattern and perception of resistance management strategies by farmers were assessed. RESULTS: The majority of farmers (88%) was aware of the presence of herbicide resistance cases in Germany and 64% and 50% of farmers reported that resistant weeds were detected in their county or on their farm, respectively...
November 17, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29148330/risk-factors-for-falls-among-older-adults-following-transition-from-nursing-home-to-the-community
#14
Jing Marrero, Richard H Fortinsky, George A Kuchel, Julie Robison
This study analyzes the incidence of falls for older adults who transitioned from institutions to the community through the Connecticut Money Follows the Person demonstration program, identifying intrinsic and extrinsic fall risk factors for this population. This prospective cohort study analyzed data from 648 Money Follows the Person participants aged 65 years and older, using 6- and 12-month posttransition surveys. Of the 648 participants, 161 (25.2%) fell in the first 6 months after transition, while 156 (24...
March 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29148146/factors-influencing-nurse-assessed-quality-nursing-care-a-cross-sectional-study-in-hospitals
#15
Ying Liu, Yupin Aungsuroch
AIM: To propose a hypothesized theoretical model and apply it to examine the structural relationships among work environment, patient-to-nurse ratio, job satisfaction, burnout, intention to leave and quality nursing care. BACKGROUND: Improving quality nursing care is a first consideration in nursing management globally. A better understanding of factors influencing quality nursing care can help hospital administrators implement effective programs to improve quality of services...
November 17, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29147951/satisfaction-with-mental-health-navigation-services-piloting-an-evaluation-with-a-new-scale
#16
Keera N Fishman, Anthony J Levitt, Roula Markoulakis, Staci Weingust
As mental health navigation services continue to be implemented, the need for valid and reliable tools to assess the quality of these services increases. While case managers target individuals with severe mental illness and aim to reduce burden and cost, and increase independence, navigation services target all individuals with a range of mental health and/or substance use issues, with the aim of reducing barriers to treatment and coordinating individualized care. The current study evaluated satisfaction with a navigation service using a new 22-item questionnaire, the Navigation Satisfaction Tool (NAVSAT)...
November 16, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/29147863/prognostic-relevance-of-programmed-cell-death-ligand-1-expression-in-glioblastoma
#17
Kyu Sang Lee, Kyoungyul Lee, Sumi Yun, Seyoung Moon, Yujun Park, Jung Ho Han, Chae-Yong Kim, Hye Seung Lee, Gheeyoung Choe
The aim of this study was to determine the clinicopathological significance of programmed cell death ligand 1 (PD-L1) expression in glioblastoma (GBM). In a retrospective cohort of 115 consecutive patients with GBM, PD-L1 expression was determined using immunohistochemistry (IHC). Membranous and fibrillary PD-L1 staining of any intensity in > 5% neoplastic cells and tumour infiltrating immune cells (TIIs) was considered positive staining. In addition, isocitrate dehydrogenase-1 (IDH-1) (R132H) expression and cluster of differentiation 3 (CD3)-positive T-cell infiltration were investigated using IHC...
November 16, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29147079/laboratory-evaluation-of-residual-efficacy-of-actellic-300-cs-pirimiphos-methyl-and-k-othrine-wg-250-deltamethrin-on-different-indoor-surfaces
#18
Kolade T Ibrahim, Kehinde O Popoola, Kenneth O Akure
The nature and type of local indoor resting wall surfaces to certain level influences the residual bio-efficacy of insecticides used in indoor residual spraying programs. Knockdown and mortality effects of an organophosphate Actellic 300 CS and pyrethroid K-Othrine WG 250 insecticides on the field-collected Culex quinquefasciatus were assessed bimonthly from July to November 2014, using World Health Organization (WHO) cones bioassay test. Knockdown and mortality rates were subjected to statistical analysis using χ(2) and Student t tests...
2017: International Journal of Insect Science
https://www.readbyqxmd.com/read/29146737/rheumatic-disorders-associated-with-immune-checkpoint-inhibitors-in-patients-with-cancer-clinical-aspects-and-relationship-with-tumour-response-a-single-centre-prospective-cohort-study
#19
Marie Kostine, Léa Rouxel, Thomas Barnetche, Rémi Veillon, Florent Martin, Caroline Dutriaux, Léa Dousset, Anne Pham-Ledard, Sorilla Prey, Marie Beylot-Barry, Amaury Daste, Marine Gross-Goupil, Julie Lallier, Alain Ravaud, Edouard Forcade, Bernard Bannwarth, Marie-Elise Truchetet, Christophe Richez, Nadia Mehsen, Thierry Schaeverbeke
OBJECTIVES: To evaluate the prevalence and type of rheumatic immune-related adverse events (irAEs) in patients receiving immune checkpoint inhibitors (ICIs), as well as the correlation with tumour response. METHODS: This was a single-centre prospective observational study including all cancer patients receiving ICIs. The occurrence of irAEs and tumour response was assessed on a regular basis. Patients who experienced musculoskeletal symptoms were referred to the department of rheumatology for clinical evaluation and management...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29146566/improving-transition-to-employment-for-youth-with-physical-disabilities-protocol-for-a-peer-electronic-mentoring-intervention
#20
Sally Lindsay, Jennifer Stinson, Mary Stergiou-Kita, Joanne Leck
BACKGROUND: Although youth with disabilities have much to gain from employment readiness programs, they are often excluded from or have limited access to vocational programs. One encouraging approach to address gaps in vocational programming is through peer electronic mentoring (e-mentoring), which may facilitate a smoother transition to adulthood by offering support to enhance coping skills. Despite the increase in online communities, little is known about their impact on vocational mentoring for youth with physical disabilities and their parents...
November 16, 2017: JMIR Research Protocols
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