keyword
MENU ▼
Read by QxMD icon Read
search

CB

keyword
https://www.readbyqxmd.com/read/29243876/familial-transmission-of-externalizing-syndromes-in-extended-swedish-families
#1
Kenneth S Kendler, Henrik Ohlsson, Jan Sundquist, Kristina Sundquist
Risk for criminal behavior (CB), alcohol use disorder (AUD), and drug abuse (DA) are known to be familial. We know less about their transmission across three generations. We examined 844,109 probands born in Sweden 1980-1990, their parents, aunts/uncles, and grandparents for registration in population-based registers for CB, AUD, and DA. Mean tetrachoric relative-proband correlations (95% CIs) were highest for DA (+0.24, 0.24-0.25), followed by CB (+0.23,0.22-0.23) and AUD (+0.17, 0.16-0.17). AUD and CB were relatively stably transmitted across generations, while DA resemblance among relatives was stronger in the younger generations...
December 15, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29242997/synergistic-production-of-20-s-protopanaxadiol-from-protopanaxadiol-type-ginsenosides-by-%C3%AE-glycosidases-from-dictyoglomus-turgidum-and-caldicellulosiruptor-bescii
#2
Ji-Hyeon Choi, Min-Ju Seo, Kyung-Chul Shin, Ki Won Lee, Deok-Kun Oh
20(S)-Protopanaxadiol (APPD) has potential uses in the pharmaceutical, cosmetic, and food industries because of its anti-stress, anti-fatigue, anti-cancer, anti-inflammatory, and anti-wrinkle properties. However, APPD production is difficult because β-glycosidases that convert the protopanaxadiol (PPD)-type ginsenoside compound K to APPD are rare. β-Glycosidase from Dictyoglomus turgidum (DT-bgl) has the highest specific activity for converting compound K to APPD, but exhibits no activity towards the α-L-arabinopyranoside moiety in compound Y...
December 14, 2017: AMB Express
https://www.readbyqxmd.com/read/29237838/a-single-amino-acid-substitution-within-the-paramyxovirus-sendai-virus-nucleoprotein-is-a-critical-determinant-for-production-of-ifn-beta-inducing-copyback-type-defective-interfering-genomes
#3
Asuka Yoshida, Ryoko Kawabata, Tomoyuki Honda, Kouji Sakai, Yasushi Ami, Takemasa Sakaguchi, Takashi Irie
One of the first defenses against infecting pathogens is the innate immune system activated by cellular recognition of pathogen-associated molecular patterns (PAMPs). Although virus-derived RNA species, especially copyback (cb)-type defective-interfering (DI) genomes, have been shown to serve as real PAMPs, which strongly induce interferon (IFN)-beta during mononegavirus infection, the mechanisms underlying DI generation remain unclear. Here, for the first time, we identified a single amino acid substitution causing production of cbDI genomes by successful isolation of two distinct types of viral clones with cbDI-producing and cbDI-non-producing phenotypes, from the stock Sendai virus (SeV) strain Cantell, which is widely used in a number of studies on anti-viral innate immunity as a representative IFN-beta-inducing virus...
December 13, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29237554/feature-based-attention-potentiates-recovery-of-fine-direction-discrimination-in-cortically-blind-patients
#4
Matthew R Cavanaugh, Antoine Barbot, Marisa Carrasco, Krystel R Huxlin
Training chronic, cortically-blind (CB) patients on a coarse [left-right] direction discrimination and integration (CDDI) task recovers performance on this task at trained, blind field locations. However, fine direction difference (FDD) thresholds remain elevated at these locations, limiting the usefulness of recovered vision in daily life. Here, we asked if this FDD impairment can be overcome by training CB subjects with endogenous, feature-based attention (FBA) cues. Ten CB subjects were recruited and trained on CDDI and FDD with an FBA cue or FDD with a neutral cue...
December 10, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29235702/in-vitro-evaluation-of-resilient-liner-after-brushing-with-conventional-and-experimental-ricinus-communis-based-dentifrices
#5
Maurício Malheiros Badaró, Talita Pereira Prates, Vanessa Maria Fagundes Leite-Fernandes, Viviane de Cássia Oliveira, Helena de Freitas Oliveira Paranhos, Cláudia Helena Silva-Lovato
PURPOSE: To evaluate the effect of experimental (Ricinus communis) and commercial dentifrices used for denture cleaning on abrasiveness (gravimetric method; roughness), hardness, and color stability of a resilient relining material. MATERIALS AND METHODS: Sixty circular (15 × 3 mm) specimens were distributed into four groups: C (control; brushing with water); CO (brushing with Colgate - for natural teeth); CB (brushing with Corega Brite - for complete dentures); RC (brushing with experimental dentifrice)...
December 13, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29232479/metabolomic-pathways-to-osteoporosis-in-middle-aged-women-a-genome-metabolome-wide-mendelian-randomization-study
#6
Alireza Moayyeri, Ching-Lung Cheung, Kathryn Cb Tan, John A Morris, Agustin Cerani, Robert P Mohney, J Brent Richard, Christopher Hammond, Tim D Spector, Cristina Menni
The metabolic state of the body can be a major determinant of bone health. We used a Mendelian Randomization approach to identify metabolites causally associated with bone mass to better understand the biological mechanisms of osteoporosis. We tested bone phenotypes (femoral neck, total hip, and lumbar spine BMD) for association with 280 fasting blood metabolites in 6055 women from TwinsUK cohort with genome-wide genotyping scans. Causal associations between metabolites and bone phenotypes were further assessed in a bidirectional Mendelian Randomization study using genetic markers/scores as instrumental variables...
December 12, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29227564/novel-mold-resistant-building-materials-impregnated-with-thermally-reduced-nano-silver
#7
Yen-Chi Chen, Kuo-Pin Yu, Wen-Cheng Shao, Chao-Heng Tseng, Wen-Chi Pan
In this study, we evaluated the long-term antifungal effectiveness of 3 types of interior building materials (gypsum board (GB), cement board (CB) and softwood plywood (S-PW)) impregnated with thermally reduced silver nanoparticles supported by titanium dioxide (AgNPs/TiO2 ) under 95% relative humidity for four weeks. AgNPs/TiO2 was synthesized at two thermal reduction temperatures (TRTs, 120 and 200°C) with two different AgNP weight percentages (2 and 5 wt%). Four different silver loading levels (SLLs, 0...
December 11, 2017: Indoor Air
https://www.readbyqxmd.com/read/29227008/ice-or-fire-comparison-of-second-generation-cryoballoon-ablation-and-radiofrequency-ablation-in-patients-with-symptomatic-persistent-atrial-fibrillation-and-an-enlarged-left-atrium
#8
Ersan Akkaya, Alexander Berkowitsch, Sergej Zaltsberg, Harald Greiss, Christian W Hamm, Johannes Sperzel, Thomas Neumann, Malte Kuniss
INTRODUCTION: We aimed to compare arrhythmia recurrence rates after second-generation cryoballoon (CB-Adv) ablation and radiofrequency (RF) ablation in patients with symptomatic persistent atrial fibrillation (AF) and left atrial (LA) enlargement. METHODS AND RESULTS: Persistent AF patients with LA enlargement were compared using a propensity-score-matching algorithm, and 111 patients treated with CB-Adv ablation and 111 patients treated with RF ablation were selected...
December 11, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29226799/evaluation-of-a-school-based-cognitive-behavioral-depression-prevention-program
#9
Pernilla Garmy, Eva K Clausson, Agneta Berg, Katarina Steen Carlsson, Ulf Jakobsson
AIM: The aim of this study was to investigate the feasibility and cost-utility of a school-based cognitive-behavioral (CB) depression prevention program. METHODS: A quasi-experimental trial with an intervention group and a control group, with follow-up measurements obtained at three and 12 months after baseline, was conducted. The setting was six Swedish municipalities. The participants were students in grade 8 (median age: 14). A total of 462 students (79% girls) were allocated to the school-based CB prevention program, and 486 students (46% girls) were allocated to the control group...
December 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29226709/enhanced-brain-network-activity-in-complex-movement-rhythms-a-simultaneous-fmri-eeg-study
#10
Bhim Mani Adhikari, Charles M Epstein, Mukesh Dhamala
Generating movement rhythms is known to involve a network of distributed brain regions associated with motor planning, control, execution, and perception of timing for the repertoire of motor actions. What brain areas are bound in the network and how the network activity is modulated by rhythmic complexity have not been completely explored. To contribute to answering these questions, we designed a study in which nine healthy participants performed simple to complex rhythmic finger movement tasks while undergoing simultaneous functional magnetic resonance imaging and electroencephalography (fMRI-EEG) recordings of their brain activity during the tasks and rest...
December 10, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/29225299/predictors-of-a-persistent-status-of-pulmonary-vein-electrical-isolation-by-a-cryoballoon-application-for-drug-refractory-atrial-fibrillation
#11
Naohiko Kawaguchi, Kaoru Okishige, Yasuteru Yamauchi, Manabu Kurabayashi, Kenzo Hirao
BACKGROUND: Pulmonary vein isolation (PVI) using a cryoballoon (CB) is utilized for treating atrial fibrillation. This study aimed to assess the effect of the procedural characteristics of CB-based PVI (CB-PVI) on late PV reconnections.Methods and Results:A total of 389 consecutive patients underwent the CB-PVI as their index procedure; 45 consecutive patients underwent re-do procedures (184±87 days after the index CB-PVI). A total of 146 of 178 PVs (82%) remained isolated. The occlusion grade was evaluated in 171 PVs...
December 8, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29223457/adsorption-behavior-and-mechanism-of-acidic-blue-25-dye-onto-cucurbit-8-uril-a-spectral-and-dft-study
#12
Hanhan Luo, Xiangyu Huang, Yuhan Luo, Zhuang Li, Lan Li, Chao Gao, Jinyan Xiong, Wei Li
The acidic blue 25 (AB25) dye was efficiently adsorbed by CB [8]; the saturated adsorption capacity (qexp) reached 434.8mg/g and was far higher than those of previous reported adsorbents. The Langmuir and Freundich isotherms were used to fit the equilibrium data, and the results showed that the Freundlich isotherm seemed to agree better with the AB25 adsorption. The adsorption kinetics followed the pseudo-second-order model. Calculated thermodynamic parameters showed that the adsorption of AB25 onto CB [8] was a spontaneous and enthalpy-driven process...
December 5, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29222976/enhanced-electrocatalytic-activity-and-stability-of-monodisperse-pt-nanocomposites-for-direct-methanol-fuel-cells
#13
Sinan Eris, Zeynep Daşdelen, Fatih Sen
Direct methanol fuel cells (DMFCs) are one of the most important fuel cells operating at low temperature using methanol as fuel and they need very efficient catalysts to activate the methanol. Generally, the most efficient fuel cell catalysts are platinum-based nanoparticles that can be used by different supporting materials such as different as prepared and functionalized carbon derivatives. For this purpose, herein, the carbon black has been mainly functionalized with an acidification process in order to increase the electrical conductivity and heterogeneous electron transfer rate of supporting materials...
December 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29221292/a-comparative-study-of-conventional-cytology-and-cell-block-method-in-the-diagnosis-of-pleural-effusion
#14
Theerada Assawasaksakul, Viboon Boonsarngsuk, Pimpin Incharoen
Background: In a patient with pleural effusion, cytological study (CS) is one of the most useful investigations, especially when malignancy is suspected. Instead of applying only CS, the pleural fluid can be further processed using the cell block (CB) technique, which may augment the diagnostic utility. The aim of this study was to compare the diagnostic yields of CS, CB, and the combination of both, regardless of the etiology of pleural effusion. Methods: A cross-sectional study was conducted on patients with pleural effusions who underwent thoracentesis from June 2015 to May 2016...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29218907/emergence-of-pathway-level-composite-biomarkers-from-converging-gene-set-signals-of-heterogeneous-transcriptomic-responses
#15
Samir Rachid Zaim, Qike Li, A Grant Schissler, Yves A Lussier
Recent precision medicine initiatives have led to the expectation of improved clinical decisionmaking anchored in genomic data science. However, over the last decade, only a handful of new single-gene product biomarkers have been translated to clinical practice (FDA approved) in spite of considerable discovery efforts deployed and a plethora of transcriptomes available in the Gene Expression Omnibus. With this modest outcome of current approaches in mind, we developed a pilot simulation study to demonstrate the untapped benefits of developing disease detection methods for cases where the true signal lies at the pathway level, even if the pathway's gene expression alterations may be heterogeneous across patients...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29217026/ciliary-body-location-in-eyes-with-and-without-primary-congenital-glaucoma
#16
Ghadah Al Nosair, Rajiv Khandekar, Mohammed Al-Shamrani, Deepak P Edward
OBJECTIVE: To compare the location of ciliary body (CB) in children with and without primary congenital glaucoma (PCG). METHODS: In this cross-sectional study, we enrolled Saudi children who were less than 5 years old. CB distance (CBD) was measured and compared in eyes with PCG (PCG group) and without PCG (control group). CBD was measured with a caliper and defined as the distance between the edge of the corneoscleral limbus and the anterior edge of CB as delineated by transillumination...
December 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29214671/multilayer-cucurbit-6-uril-based-magnetic-nanoparticles-prepared-via-host-guest-interaction-remarkable-adsorbent-for-the-removal-of-low-density-lipoprotein-from-plasma
#17
Dandan Jiang, Xiqian Li, Qiong Jia
Efficient removal of low density lipoprotein (LDL) is a key challenge since its high level in plasma is a primary risk factor in the pathogenesis of atherosclerotic cardiovascular disease. In this work, a facile synthesis strategy based on host-guest interactions was developed to prepare multilayer cucurbit[6]uril-based magnetic nanoparticles, MNPs-(HA-DAH5/HA-CB[6]5). The compound was employed as a blood purification material for the removal of LDL from plasma because it had good blood compatibilitiy and could be easily separated with an external magnet...
December 6, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29214478/cigarette-butts-abundance-and-association-of-mercury-and-lead-along-the-persian-gulf-beach-an-initial-investigation
#18
Sina Dobaradaran, Torsten C Schmidt, Iraj Nabipour, Afshin Ostovar, Alireza Raeisi, Reza Saeedi, Maryam Khorsand, Nahid Khajeahmadi, Mozhgan Keshtkar
The toxic metal contents of cigarette butts and distribution of cigarette butts have not been studied well in maritime environment. In the present study, cigarette butts distribution and the associations of Hg and Pb from cigarette butts were monitored along the Persian Gulf with 10 days interval sampling time. The number of cigarette butts, and Hg and Pb associations of butts were found to vary widely between 2 and 38 items per square meter, 2.5 and 86.32 ng/g cigarette butt (CB), as well as 650 and 8630 ng/g CB, respectively...
December 7, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29214038/cell-bound-complement-activation-products-in-sle
#19
REVIEW
Rosalind Ramsey-Goldman, Jian Li, Thierry Dervieux, Roberta Vezza Alexander
Diagnosis of SLE is based on clinical manifestations and laboratory findings. Timely diagnosis and treatment are important to control disease activity and prevent organ damage. However, diagnosis is challenging because of the heterogeneity in clinical signs and symptoms, and also because the disease presents with alternating periods of flare and quiescence. As SLE is an autoimmune disease characterised by the formation of autoantibodies, diagnostic immunology laboratory tests for detecting and quantifying autoantibodies are commonly used for the diagnosis and classification of SLE...
2017: Lupus Science & Medicine
https://www.readbyqxmd.com/read/29211812/a-simulation-study-on-the-impact-of-the-blood-flow-dependent-component-in-18f-av45-suvr-in-alzheimer-s-disease
#20
Julie Ottoy, Jeroen Verhaeghe, Ellis Niemantsverdriet, Sebastiaan Engelborghs, Sigrid Stroobants, Steven Staelens
BACKGROUND: Increased brain uptake on [18F]AV45 PET is a biomarker for Alzheimer's disease (AD). The standardised uptake value ratio (SUVR) is widely used for quantification but is subject to variability. Here we evaluate how SUVR of a cortical target region is affected by blood flow changes in the target and two frequently used reference regions. METHODS: Regional baseline time-activity curves (TACs) were simulated based on metabolite-corrected plasma input functions and pharmacokinetic parameters obtained from our previously acquired data in healthy control (HC; n = 10), amnestic mild cognitive impairment (aMCI; n = 15) and AD cohorts (n = 9)...
2017: PloS One
keyword
keyword
69773
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"