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https://www.readbyqxmd.com/read/28339969/the-quality-of-eggs-organic-and-nutraceutical-vs-conventional-and-their-technological-properties
#1
Agnieszka Filipiak-Florkiewicz, Katarzyna Deren, Adam Florkiewicz, Kinga Topolska, Leslaw Juszczak, Ewa Cieslik
The aim of the study was to compare the quality of commercially available eggs: organic (attested organic farm) - OE, nutraceutical (enriched in n-3 fatty acids) - NE, vs. conventional (cage raising system) - CE and their technological (emulsifying) properties. Their basic chemical composition (i.e., moisture, protein, fat, ash) as well as mineral (Na, K, Ca, Mg, Zn, Fe, Mn, Cu) contents were assessed, and fatty acid profiles were determined. Next, the suitability of the eggs for mayonnaise production was assessed...
February 23, 2017: Poultry Science
https://www.readbyqxmd.com/read/28334508/dietary-fatty-acids-influence-sperm-quality-and-function
#2
A Ferramosca, N Moscatelli, M Di Giacomo, V Zara
Recently, obesity has been linked to male infertility. In animal models the administration of a high-fat diet caused a reduction in sperm quality, by impairing gamete energy metabolism. The aim of this study was to investigate a possible effect of dietary fatty acids supplementation in the modulation of sperm energy metabolism and, in turn, in the improvement of sperm quality in rats fed a high-fat diet. Sexually mature male Sprague-Dawley rats were divided into four groups and fed for 4 weeks a standard diet (control group), a high-fat diet (enriched in 35% of fat and 15% sucrose), a high-fat diet supplemented with 2...
March 23, 2017: Andrology
https://www.readbyqxmd.com/read/28332578/a-new-class-of-inhibitors-of-the-arac-family-virulence-regulator-vibrio-cholerae-toxt
#3
Anne K Woodbrey, Evans O Onyango, Maria Pellegrini, Gabriela Kovacikova, Ronald K Taylor, Gordon W Gribble, F Jon Kull
Vibrio cholerae is responsible for the diarrheal disease cholera that infects millions of people worldwide. While vaccines protecting against cholera exist, and oral rehydration therapy is an effective treatment method, the disease will remain a global health threat until long-term solutions such as improved sanitation and access to clean water become widely available. Because of this, there is a pressing need for potent therapeutics that can either mitigate cholera symptoms, or act prophylactically to prevent the virulent effects of a cholera infection...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327516/an-extract-from-shrimp-processing-by-products-protects-sh-sy5y-cells-from-neurotoxicity-induced-by-a%C3%AE-25-35
#4
Yongping Zhang, Guangling Jiao, Cai Song, Shelly Gu, Richard E Brown, Junzeng Zhang, Pingcheng Zhang, Jacques Gagnon, Steven Locke, Roumiana Stefanova, Claude Pelletier, Yi Zhang, Hongyu Lu
Increased evidence suggests that marine unsaturated fatty acids (FAs) can protect neurons from amyloid-β (Aβ)-induced neurodegeneration. Nuclear magnetic resonance (NMR), high performance liquid chromatography (HPLC) and gas chromatography (GC) assays showed that the acetone extract 4-2A obtained from shrimp Pandalus borealis industry processing wastes contained 67.19% monounsaturated FAs and 16.84% polyunsaturated FAs. The present study evaluated the anti-oxidative and anti-inflammatory effects of 4-2A in Aβ25-35-insulted differentiated SH-SY5Y cells...
March 22, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28319105/link-of-dietary-patterns-with-metabolic-syndrome-analysis-of-the-national-health-and-nutrition-examination-survey
#5
M Mazidi, S Pennathur, F Afshinnia
BACKGROUND: Population-based interventions aimed at halting the increasing prevalence of metabolic syndrome (MetS) require thorough understanding of dietary interplays. Objective is to identify the independent dietary nutrients associated with MetS and its components using dietary pattern identification and the single-nutrient approaches in The United States. METHODS: This is a cross-sectional observation. Participants are selected from the National Health and Nutrition Examination Survey (NHANES) with available dietary intake, biochemical and anthropometrical data from 2001 to 2012...
March 20, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28304335/the-relationship-between-fatty-acids-and-different-depression-related-brain-regions-and-their-potential-role-as-biomarkers-of-response-to-antidepressants
#6
REVIEW
Maria Fernanda Fernandes, David M Mutch, Francesco Leri
Depression is a complex disorder influenced by a variety of biological and environmental factors. Due to significant heterogeneity, there are remarkable differences in how patients respond to treatment. A primary objective of psychiatric research is to identify biological markers that could be used to better predict and enhance responses to antidepressant treatments. Diet impacts various aspects of health, including depression. The fatty acid composition of the Western diet, which has a high ratio of n-6:n-3 polyunsaturated fatty acids, is associated with increased incidence of depression...
March 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28304067/lipid-remodelling-in-human-melanoma-cells-in-response-to-uva-exposure
#7
Elisabete Maciel, Juliana Felgueiras, Eduarda M P Silva, Fernando Ricardo, Ana S P Moreira, Tânia Melo, Ana Campos, Margarida Fardilha, Pedro Domingues, M Rosário Domingues
Extensive exposure to UVA is thought to increase the risk of malignancy and the progression of melanoma, the most serious type of skin cancer. It is well known that alterations in lipid metabolism represent an early event in carcinogenesis, but the impact of UVA exposure on the lipid composition of cancer cells is still largely unknown. In this study we aimed at investigating lipid remodeling in human melanoma cells in response to UVA exposure. After UVA irradiation, lipid extracts were either immediately collected from SK-MEL-28 cells or collected after a recovery period of 2 h or 24 h...
March 17, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28298542/lipid-emulsion-added-to-a-liquid-high-carbohydrate-diet-and-voluntary-running-exercise-reduce-lipogenesis-and-ameliorate-early-stage-hepatic-steatosis-in-mice
#8
Kuan-Hsun Huang, Lei Hao, Philip B Smith, Connie J Rogers, Andrew D Patterson, A Catharine Ross
Background: The use of parenteral nutrition formulas is often associated with the development of hepatic steatosis. We have shown previously that the addition of a lipid emulsion (LE) rich in n-6 (ω-6) fatty acids (FAs) ameliorated triglyceride (TG) accumulation in the livers of nonobese mice fed a high-carbohydrate diet (HCD) for 5 wk. However, it remains unclear how rapidly this condition develops and whether it can be prevented by LE with or without a running wheel for voluntary exercise (Exe).Objective: We investigated in an 8-d study whether mice develop steatosis and whether the administration of LE with or without Exe reduces the concentration of total FAs and prevents an increase in the expression of genes in the liver associated with lipogenesis...
March 15, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28298293/discovery-and-fine-mapping-of-loci-associated-with-monounsaturated-fatty-acids-through-trans-ethnic-meta-analysis-in-chinese-and-european-populations
#9
Yao Hu, Toshiko Tanaka, Jingwen Zhu, Weihua Guan, Jason H Y Wu, Bruce M Psaty, Barbara McKnight, Irena B King, Qi Sun, Melissa Richard, Ani Manichaikul, Alexis C Frazier-Wood, Edmond K Kabagambe, Paul N Hopkins, Jose M Ordovas, Luigi Ferrucci, Stefania Bandinelli, Donna K Arnett, Yii-Der I Chen, Shuang Liang, David S Siscovick, Michael Y Tsai, Stephen S Rich, Myriam Fornage, Frank B Hu, Eric B Rimm, Majken K Jensen, Rozenn N Lemaitre, Dariush Mozaffarian, Lyn M Steffen, Andrew P Morris, Huaixing Li, Xu Lin
Monounsaturated fatty acids (MUFAs) are unsaturated fatty acids with one double bond and are derived from endogenous synthesis and dietary intake. Accumulating evidence has suggested that plasma and erythrocyte MUFA levels were associated with cardiometabolic disorders including cardiovascular disease (CVD), type 2 diabetes (T2D) and metabolic syndrome (MS). Previous genome-wide association studies (GWAS) have identified seven loci for plasma and erythrocyte palmitoleic acid and oleic acid levels in populations of European origin...
March 15, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28297799/-a-serum-lipidomic-study-of-patients-with-non-alcoholic-fatty-liver-disease
#10
R X Yang, C X Hu, Y Q Mi, W L Sun, G Y Chen, Q Pan, F Shen, G W Xu, J G Fan
Objective: To investigate the serum lipidomic profile in patients with nonalcoholic fatty liver disease (NAFLD), and to analyze the lipid metabolism characteristics of NAFLD. Methods: The subjects were divided into control group (23 patients) and pathologically confirmed NAFLD group (42 patients), and ultra-high-performance liquid chromatography-tandem mass spectrometry was used to measure serum lipidomic metabolites. The partial least squares-discriminant analysis (PLS-DA) model was established to analyze the differences in lipid metabolism with reference to the univariate analysis...
February 20, 2017: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/28297159/identification-of-leptin-gene-polymorphisms-associated-with-carcass-traits-and-fatty-acid-composition-in-japanese-black-cattle
#11
Fuki Kawaguchi, Kazuki Okura, Kenji Oyama, Hideyuki Mannen, Shinji Sasazaki
Previous studies have indicated that some leptin gene polymorphisms were associated with economically important traits in cattle breeds. However, polymorphisms in the leptin gene have not been reported thus far in Japanese Black cattle. Here, we aimed to identify the leptin gene polymorphisms which are associated with carcass traits and fatty acid composition in Japanese Black cattle. We sequenced the full-length coding sequence of leptin gene for eight Japanese Black cattle. Sequence comparison revealed eight single nucleotide polymorphisms (SNPs)...
March 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28287421/in-depth-lipidomic-analysis-of-molecular-species-of-triacylglycerides-diacylglycerides-glycerophospholipids-and-sphingolipids-of-buttermilk-by-gc-ms-fid-hplc-elsd-and-uplc-qtof-ms
#12
Pilar Castro-Gómez, Olimpio Montero, Javier Fontecha
Buttermilk, a byproduct of butter manufacturing, has gained considerable attention due to its high concentration of polar lipids as phospho- and sphingolipids from the milk fat globule membrane (MFGM). These polar lipids (PLs) are essential components of all cellular membranes and exert a variety of indispensable metabolic, neurological, and intracellular signaling processes. Despite its importance, there are few research studies that report a comprehensive characterization of the lipid molecular species of MFGM that could contribute to a better understanding of their putative healthful activities...
March 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28286737/pdgf-induced-fibroblast-growth-requires-monounsaturated-fatty-acid-production-by-stearoyl-coa-desaturase
#13
Alexandra Coomans de Brachène, Nicolas Dif, Audrey de Rocca Serra, Chloé Bonnineau, Amélie I Velghe, Yvan Larondelle, Donatienne Tyteca, Jean-Baptiste Demoulin
Stearoyl-coenzyme A desaturase (SCD) catalyzes the Δ9-cis desaturation of saturated fatty acids (SFA) to generate monounsaturated fatty acids (MUFA). This enzyme is highly up-regulated by platelet-derived growth factor (PDGF) in human fibroblasts. Accordingly, the analysis of cellular fatty acids by gas chromatography showed that PDGF significantly increased the proportion of MUFA, particularly palmitoleate, in cellular lipids. To further analyze the role of SCD in fibroblasts, we used small hairpin RNA targeting SCD (shSCD), which decreased the MUFA content...
March 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/28285975/monounsaturated-fatty-acids-might-be-key-factors-in-the-mediterranean-diet-that-suppress-rheumatoid-arthritis-disease-activity-the-tomorrow-study
#14
Yoshinari Matsumoto, Yuko Sugioka, Masahiro Tada, Tadashi Okano, Kenji Mamoto, Kentaro Inui, Daiki Habu, Tatsuya Koike
BACKGROUND & AIMS: The Mediterranean diet is reportedly effective in suppressing disease activity in rheumatoid arthritis (RA), but the key elements responsible for this effect remain unknown. The presented study therefore aimed to identify such elements. METHODS: This study included 208 consecutive patients with RA (RA group) and 205 age- and sex-matched healthy volunteers (controls) from the prospective "TOMORROW" cohort study that has been ongoing since 2010 were included in this study...
February 21, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28273841/comprehensive-metabolomic-analysis-in-blood-urine-fat-and-muscle-in-men-with-metabolic-syndrome-a-randomized-placebo-controlled-clinical-trial-on-the-effects-of-resveratrol-after-four-months-treatment
#15
Anne Sofie Korsholm, Thomas Nordstrøm Kjær, Marie Juul Ornstrup, Steen Bønløkke Pedersen
Resveratrol possesses several beneficial metabolic effects in rodents, while the effects of resveratrol in humans remain unclear. Therefore, we performed a non-targeted comprehensive metabolomic analysis on blood, urine, adipose tissue, and skeletal muscle tissue in middle-aged men with metabolic syndrome randomized to either resveratrol or placebo treatment for four months. Changes in steroid hormones across all four matrices were the most pronounced changes observed. Resveratrol treatment reduced sulfated androgen precursors in blood, adipose tissue, and muscle tissue, and increased these metabolites in urine...
March 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28270158/replacing-american-snacks-with-tree-nuts-increases-consumption-of-key-nutrients-among-us-children-and-adults-results-of-an-nhanes-modeling-study
#16
Colin D Rehm, Adam Drewnowski
BACKGROUND: Replacing typical American snacks with tree nuts may be an effective way to improve diet quality and compliance with the 2015-2020 Dietary Guidelines for Americans (DGAs). OBJECTIVE: To assess and quantify the impact of replacing typical snacks with composite tree nuts or almonds on diet metrics, including empty calories (i.e., added sugars and solid fats), individual fatty acids, macronutrients, nutrients of public health concern, including sodium, fiber and potassium, and summary measures of diet quality...
March 7, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28264745/dietary-verbascoside-supplementation-in-donkeys-effects-on-milk-fatty-acid-profile-during-lactation-and-serum-biochemical-parameters-and-oxidative-markers
#17
A G D'Alessandro, F Vizzarri, M Palazzo, G Martemucci
Various uses of donkeys' milk have been recently proposed for human consumption on the basis of its nutritional characteristics. Improvements in milk fatty acid profile and animal oxidative status can be induced through dietary supplementation of phenolic compounds. The study aimed to evaluate in donkeys the effects of dietary supplementation with verbascoside (VB) on: (i) the fatty acid profile and vitamins A and E contents of milk during a whole lactation, and (ii) blood biochemical parameters and markers of oxidative status of the animals...
March 7, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28261812/the-fatty-acid-profile-of-fat-depots-from-santa-in%C3%A3%C2%AAs-sheep-fed-spineless-cactus-opuntia-ficus-indica-mill
#18
Roberto G Costa, Michelly D A Almeida, George Rodrigo B Cruz, Edvaldo M Beltrão Filho, Neila L Ribeiro, Marta S Madruga, Rita de Cássia R E Queiroga
BACKGROUND: Fat is the tissue that varies most in animals from both a quantitative and distribution perspective. It plays a fundamental biological role as energy storage during food scarcity. Renal, pelvic and internal fat are deposited first. These fats are used identify fatty acid profiles that may be considered beneficial or unhealthy. The aim of this study is to evaluate the fatty acid profile of fat depots in Santa Inês sheep finished in confinement with spineless cactus in their diets...
March 6, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28259683/inhibition-of-sebum-production-with-the-acetyl-coenzyme-a-carboxylase-inhibitor-olumacostat-glasaretil
#19
David W Hunt, Geoffrey C Winters, Roger W Brownsey, Jerzy E Kulpa, Kathryn L Gilliland, Diane M Thiboutot, Hans E Hofland
Olumacostat glasaretil (OG) is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC), the enzyme which controls the first, rate limiting step in fatty acid biosynthesis. Inhibition of ACC activity in the sebaceous glands is designed to substantially impact sebum production since over 80% of human sebum components contain fatty acids. OG inhibits de novo lipid synthesis in primary and transformed human sebocytes. TrueMass® Sebum Panel analyses revealed a reduction in saturated and monounsaturated fatty acyl chains across lipid species, including di- and triacylglycerols, phospholipids, cholesteryl esters, and wax esters in OG treated sebocytes...
March 1, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28254018/volatile-flavor-constituents-in-the-pork-broth-of-black-pig
#20
Jian Zhao, Meng Wang, Jianchun Xie, Mengyao Zhao, Li Hou, Jingjing Liang, Shi Wang, Jie Cheng
Pork of black-pig in China is well known for its quality and preferred by consumers. However, there is a lack of research on its flavors. By solvent assisted flavor evaporation combined with GC-MS, 104 volatile compounds in the stewed pork broth of black-pig were identified with the dominant amounts of fatty acids, alcohols, and esters. By aroma extract dilution analysis-GC-O method, 27 odor-active compounds were characterized, including 2-methyl-3-furanthiol, 3-(methylthio)propanal, 2-furfurylthiol, γ-decalactone, nonanal, (E)-2-nonenal, and (E,E)-2,4-decadienal that had high FD factors...
July 1, 2017: Food Chemistry
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