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food antibiotic residues

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https://www.readbyqxmd.com/read/27879173/residue-depletion-of-oxytetracycline-otc-and-4-epi-oxytetracycline-4-epi-otc-in-broiler-chicken-s-claws-by-liquid-chromatography-tandem-mass-spectrometry-lc-ms-ms
#1
J Cornejo, E Pokrant, D Araya, C Briceño, H Hidalgo, A Maddaleno, C Araya-Jordán, B San Martin
Antibiotics are widely used in poultry production for treatment of bacterial diseases. However, residues may remain in products and by-products destined for human consumption or animal feeding. The claws of chickens are a by-product from the poultry industry, which can directly or indirectly enter the food chain as meals destined to feed other productive animals. Thus, it becomes necessary to determine and quantify antimicrobial residues present in this matrix. The objective of the present study was to assess the depletion of oxytetracycline (OTC) and its metabolite 4-epi-OTC in broiler chicken's claws...
November 23, 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/27873208/validation-procedure-for-multiplex-antibiotic-immunoassays-using-flow-based-chemiluminescence-microarrays
#2
Verena Katharina Meyer, Daniela Meloni, Fabio Olivo, Erwin Märtlbauer, Richard Dietrich, Reinhard Niessner, Michael Seidel
Small molecules like antibiotics or other pharmaceuticals can be detected and quantified, among others, with indirect competitive immunoassays. With regard to multiplex quantification, these tests can be performed as chemiluminescence microarray immunoassays, in which, in principle, the analyte in the sample and the same substance immobilized on the chip surface compete for a limited number of specific antibody binding sites. The amount of the specific primary antibody that has been bound to the surface is visualized by means of a chemiluminescence reaction...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27857835/antibiotics-practice-and-opinions-of-cambodian-commercial-farmers-animal-feed-retailers-and-veterinarians
#3
Chhorvoin Om, Mary-Louise McLaws
BACKGROUND: Cambodia has reported multidrug resistant bacteria in poultry, similar to other countries in the region. We visited commercial food animal farms to explore opinions and antibiotic practices on the farms. METHODS: We used individual in-depth qualitative interviews with 16 commercial farmers, four feed retailers and nine veterinarians from food animal industry and government offices from the southwestern region of Phnom Penh. Transcribed interviews were thematically analysed...
2016: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/27826358/use-of-molecular-typing-to-investigate-bacterial-translocation-from-the-intestinal-tract-of-chlorpyrifos-exposed-rats
#4
Claire Joly Condette, Bertin Elion Dzon, Farida Hamdad, Maurice Biendo, Véronique Bach, Hafida Khorsi-Cauet
BACKGROUND: Human are confronted on a daily basis with contaminant pesticide residues in food, water and other components of the environment. Although the digestive system is the first organ to come into contact with food contaminants, very few data are available on the impact of low-dose pesticide exposure during the in utero and postnatal periods on intestinal bacterial translocation (BT). Previous studies have revealed that chlorpyrifos (CPF) exposure is associated with intestinal dysbiosis and the contamination of sterile organs...
2016: Gut Pathogens
https://www.readbyqxmd.com/read/27816225/multiresidue-analysis-of-cephalosporin-antibiotics-in-bovine-milk-based-on-molecularly-imprinted-polymer-extraction-followed-by-liquid-chromatography-tandem-mass-spectrometry
#5
A N Baeza, J L Urraca, R Chamorro, G Orellana, M Castellari, M C Moreno-Bondi
This work reports the preparation of molecularly imprinted polymers (MIPs) selective to cephalosporin (CF) antibiotics, and their application as molecularly imprinted solid-phase extraction (MISPE) sorbents for the determination of these antimicrobials in milk samples. Several functional monomers and cross-linkers have been screened to select the best combination that provides high selectivity for the simultaneous multiresidue extraction of cefthiofur (THIO), cefazolin (AZO), cefquinome (QUI), cephapirin (API), cephalexin (ALE) and cephalonium (ALO) from the samples...
October 29, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27807600/metagenomic-analysis-reveals-the-influences-of-milk-containing-antibiotics-on-the-rumen-microbes-of-calves
#6
Wei Li, Yunsheng Han, Xue Yuan, Guan Wang, Zhibo Wang, Qiqi Pan, Yan Gao, Yongli Qu
Milk containing antibiotics is used as cost-effective feed for calves, which may lead to antibiotic residues-associated food safety problems. This study aims to investigate the influence of antibiotics on rumen microbes. Through metagenomic sequencing, the rumen microbial communities of calves fed with pasteurized milk containing antibiotics (B1), milk containing antibiotics (B2) and fresh milk (B3) were explored. Each milk group included calves in 2 (T1), 3 (T2) and 6 (T3) months of age. Using FastQC software and SOAPdenovo 2, the filtered data, respectively, were performed with quality control and sequence splicing...
November 2, 2016: Archives of Microbiology
https://www.readbyqxmd.com/read/27752951/veterinary-pharmaceuticals-in-aqueous-systems-and-associated-effects-an-update
#7
Samuel Obimakinde, Olalekan Fatoki, Beatrice Opeolu, Olatunde Olatunji
Environmental studies have shown that pharmaceuticals can contaminate aqueous matrices, such as groundwater, surface water, sediment as well as aquatic flora and fauna. Effluents from sewage and wastewater treatment plants, pharmaceutical industries and hospitals have been implicated in such contamination. Recent studies have however revealed significant concentrations of pharmaceuticals in wastewater from animal facilities in proximal aquatic habitats. Furthermore, epidemiological studies have shown a consistent positive correlation between exposure to some drugs of veterinary importance and increased adverse effects in aquatic biota largely due to induction of endocrine disruption, antibiotic resistance, neurotoxicity, genotoxicity and oxidative stress...
October 18, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27752947/use-of-commercial-organic-fertilizer-increases-the-abundance-of-antibiotic-resistance-genes-and-antibiotics-in-soil
#8
Xue Zhou, Min Qiao, Feng-Hua Wang, Yong-Guan Zhu
The application of manure-based commercial organic fertilizers (COFs) is becoming increasingly extensive because of the expanding market for organic food. The present study examined the effects of repeated applications of chicken or swine manure-based COFs on the fate of antibiotics and antibiotic resistance genes (ARGs) in soil by conducting a soil microcosm experiment. Application of COFs significantly increased antibiotics residues, as well as the relative abundance of ARGs and the integrase gene of class 1 integrons (intΙ1) in soil...
October 17, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27750097/food-safety-in-scavenger-conservation-diet-associated-exposure-to-livestock-pharmaceuticals-and-opportunist-mycoses-in-threatened-cinereous-and-egyptian-vultures
#9
Guillermo Blanco, Alexandra Junza, Dolores Barrón
Pharmaceuticals from veterinary treatments may enter terrestrial food webs when medicated livestock are available to wildlife in supplementary feeding stations aimed at the conservation of endangered scavengers. Here, we hypothesized that the exposure risk to livestock fluoroquinolones, as indicators of pharmaceutical burden in food, is related to the variable reliance of scavengers on domestic versus wild animal carcasses. Since the misuse of broad-spectrum antibiotics is a major predisposing factor for opportunistic mycoses, we evaluated disease signs potentially associated with diet-dependent drug exposure in nestlings of two threatened vultures...
October 14, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/27733794/screening-of-antibiotics-and-chemical-analysis-of-penicillin-residue-in-fresh-milk-and-traditional-dairy-products-in-oyo-state-nigeria
#10
Isaac Olufemi Olatoye, Oluwayemisi Folashade Daniel, Sunday Ayobami Ishola
BACKGROUND AND AIM: There are global public health and economic concerns on chemical residues in food of animal origin. The use of antibiotics in dairy cattle for the treatment of diseases such as mastitis has contributed to the presence of residues in dairy products. Penicillin residues as low as 1 ppb can lead to allergic reactions and shift of resistance patterns in microbial population as well as interfere with the processing of several dairy products. Antibiotic monitoring is an essential quality control measure in safe milk production...
September 2016: Veterinary World
https://www.readbyqxmd.com/read/27720116/multi-residue-analysis-of-pesticides-plant-hormones-veterinary-drugs-and-mycotoxins-using-hilic-chromatography-ms-ms-in-various-food-matrices
#11
G P Danezis, C J Anagnostopoulos, K Liapis, M A Koupparis
One of the recent trends in Analytical Chemistry is the development of economic, quick and easy hyphenated methods to be used in a field that includes analytes of different classes and physicochemical properties. In this work a multi-residue method was developed for the simultaneous determination of 28 xenobiotics (polar and hydrophilic) using hydrophilic interaction liquid chromatography technique (HILIC) coupled with triple quadrupole mass spectrometry (LC-MS/MS) technology. The scope of the method includes plant growth regulators (chlormequat, daminozide, diquat, maleic hydrazide, mepiquat, paraquat), pesticides (cyromazine, the metabolite of the fungicide propineb PTU (propylenethiourea), amitrole), various multiclass antibiotics (tetracyclines, sulfonamides quinolones, kasugamycin and mycotoxins (aflatoxin B1, B2, fumonisin B1 and ochratoxin A)...
October 26, 2016: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27597982/in-vitro-effects-of-some-botanicals-with-anti-inflammatory-and-antitoxic-activity
#12
Gianandrea Guidetti, Alessandro Di Cerbo, Angela Giovazzino, Valentina Rubino, Anna Teresa Palatucci, Sara Centenaro, Elena Fraccaroli, Laura Cortese, Maria Grazia Bonomo, Giuseppina Ruggiero, Sergio Canello, Giuseppe Terrazzano
Several extrinsic factors, like drugs and chemicals, can foster autoimmunity. Tetracyclines, in particular oxytetracycline (OTC), appear to correlate with the emergence of immune-mediated diseases. Accumulation of OTC, the elective drug for gastrointestinal and respiratory infectious disease treatment in broiler chickens, was reported in chicken edible tissues and could represent a potential risk for pets and humans that could assume this antibiotic as residue in meat or in meat-derived byproducts. We investigated the in vitro anti-inflammatory properties of a pool of thirteen botanicals as a part of a nutraceutical diet, with proven immunomodulatory activity...
2016: Journal of Immunology Research
https://www.readbyqxmd.com/read/27595038/a-confirmatory-method-based-on-hplc-ms-ms-for-the-detection-and-quantification-of-residue-of-tetracyclines-in-nonmedicated-feed
#13
Rosa E Gavilán, Carolina Nebot, Maria Veiga-Gómez, Paula Roca-Saavedra, Beatriz Vazquez Belda, Carlos M Franco, Alberto Cepeda
The Commission Regulation 574/2011/EC set up maximum levels of coccidiostats and histomonostats in nonmedicated feed as a consequence of carry-over during manufacturing. Carry-over takes place from medicated to nonmedicated feed during feed production. Similar contamination could also occur for other pharmaceuticals such as tetracyclines, a group of antibiotics commonly employed in food production animal. The objective of this work is to present a simple and fast method for the simultaneous detection of four tetracyclines (chlortetracycline, doxycycline, oxytetracycline, and tetracycline) in nontarget feed at a μg/kg level...
2016: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/27591630/combination-of-hollow-fiber-liquid-phase-microextraction-followed-by-hplc-dad-and-multivariate-curve-resolution-to-determine-antibacterial-residues-in-foods-of-animal-origin
#14
Fateme Tajabadi, Mahnaz Ghambarian, Yadollah Yamini, Najmeh Yazdanfar
In the present research, a carrier mediated hollow fiber based liquid-phase microextraction approach (HF-LPME) prior to high performance liquid chromatography-diode array detection (HPLC-DAD) was developed for the simultaneous determination of the antibacterial residues of four tetracyclines (TCs) and five quinolones (QNs), which are commonly used as veterinary medicines. In order to obtain high extraction efficiency, the parameters affecting HF-LPME were optimized using a three-factor and three-level Box-Behnken design under response surface methodology...
November 1, 2016: Talanta
https://www.readbyqxmd.com/read/27548983/-distribution-and-risk-assessment-of-sulfonamides-antibiotics-in-soil-and-vegetables-from-feedlot-livestock
#15
Cai-xia Jin, Xiao-wei Si, Zi-ying Wang, Qin-wen Zhang
Soil and vegetable samples were collected from 13 different livestock farms of different sizes in Xinxiang of China, and the residues of three sulfonamides including sulfadiazine, sulfamonomethoxine, and sulfamethoxazole were analyzed by HPLC with a fluorimetric detector, The results indicated that the total concentration ranges of the three sulfonamides in soil and vegetable were 7.60-176.26 µg · kg⁻¹ and ND-32, 70 µg · kg⁻¹, respectively. The mean concentrations were 70.73 µg · kg⁻¹ and 7.08 µg · kg⁻¹ for soil and vegetables...
April 15, 2016: Huan Jing Ke Xue= Huanjing Kexue
https://www.readbyqxmd.com/read/27462521/insights-into-the-interactions-between-tetracycline-its-degradation-products-and-bovine-serum-albumin
#16
Xingyu Tong, Manfei Mao, Jingqian Xie, Kefeng Zhang, Dongmei Xu
Tetracyclines (TCs) are the most widely used antibiotics in the world. Because antibiotics have low bioavailability and are difficult to completely remove using current sewage treatment facilities, residual TCs and their degradation products in the environment, animal and plant foodstuffs and personal care products may enter the body through the food chain, thus causing unpredictable effects on human health. We studied bovine serum albumin (BSA) (a functional protein) as a target of tetracycline-induced toxicity by examining its interactions with TC, anhydrotetracycline (ATC) and epitetracycline (ETC), based on a fluorescence spectroscopy and molecular docking method under simulated physiological conditions...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27385382/distribution-of-chloramphenicol-to-tissues-plasma-and-urine-in-pigs-after-oral-intake-of-low-doses
#17
Bitte Aspenström-Fagerlund, Erik Nordkvist, Anna Törnkvist, Per Wallgren, Ron Hoogenboom, Bjorn Berendsen, Kristina Granelli
Toxic effects of chloramphenicol in humans caused the ban for its use in food-producing animals in the EU. A minimum required performance level (MRPL) was specified for chloramphenicol at 0.3 μg kg(-1) for various matrices, including urine. In 2012, residues of chloramphenicol were found in pig urine and muscle without signs of illegal use. Regarding its natural occurrence in straw, it was hypothesised that this might be the source, straw being compulsory for use as bedding material for pigs in Sweden. Therefore, we investigated if low daily doses of chloramphenicol (4, 40 and 400 μg/pig) given orally during 14 days could result in residues in pig tissues and urine...
September 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/27379026/genomic-microbial-epidemiology-is-needed-to-comprehend-the-global-problem-of-antibiotic-resistance-and-to-improve-pathogen-diagnosis
#18
REVIEW
Ethan R Wyrsch, Piklu Roy Chowdhury, Toni A Chapman, Ian G Charles, Jeffrey M Hammond, Steven P Djordjevic
Contamination of waste effluent from hospitals and intensive food animal production with antimicrobial residues is an immense global problem. Antimicrobial residues exert selection pressures that influence the acquisition of antimicrobial resistance and virulence genes in diverse microbial populations. Despite these concerns there is only a limited understanding of how antimicrobial residues contribute to the global problem of antimicrobial resistance. Furthermore, rapid detection of emerging bacterial pathogens and strains with resistance to more than one antibiotic class remains a challenge...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27374578/monitoring-and-determination-of-sulfonamide-antibiotics-sulfamethoxydiazine-sulfamethazine-sulfamethoxazole-and-sulfadiazine-in-imported-pangasius-catfish-products-in-thailand-using-liquid-chromatography-coupled-with-tandem-mass-spectrometry
#19
Worawat Jansomboon, Suwanna Kitpati Boontanon, Narin Boontanon, Chongrak Polprasert, Chau Thi Da
This research aimed to monitor the concentrations of sulfamethoxydiazine (SMD), sulfamethazine (SMT), sulfamethoxazole (SMX) and sulfadiazine (SDZ) in imported Pangasius catfish products in Thailand. The residues of the four sulfonamides (SAs) were analyzed by extraction process and liquid chromatography coupled with tandem mass spectrometry. The highest concentrations found were 10.97ng/g for SMD, 6.23ng/g for SMT, 11.13ng/g for SDZ and 245.91ng/g for SMX, which was higher than the European Union (EU) standard (100ng/g)...
December 1, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27283636/a-high-sensitivity-terahertz-spectroscopy-technology-for-tetracycline-hydrochloride-detection-using-metamaterials
#20
Jianyuan Qin, Lijuan Xie, Yibin Ying
Antibiotic residues in animal-derived food due to their overuse in veterinary medicine will have potential adverse effects on human health. The rapid and accurate detection of these drugs is essential for ensuring human food safety. In particular, the current detection methods are usually limited by the low sensitivity or the tedious pre-treatment. Here we demonstrate that metamaterials operating at terahertz frequencies, acting as highly sensitive sensors, show promising potential for the detection of tetracycline hydrochloride (TCH)...
November 15, 2016: Food Chemistry
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