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https://www.readbyqxmd.com/read/28738316/-what-kept-me-going-a-qualitative-study-of-avoidant-responses-to-war-related-adversity-and-perpetration-of-violence-by-former-forcibly-recruited-children-and-youth-in-the-acholi-region-of-northern-uganda
#1
Helle Harnisch, Edith Montgomery
This qualitative study investigates what, according to 36 former forcibly recruited women and men, enabled them to "keep on going" during and after their forced recruitment in the twenty-year-long civil war in northern Uganda. Furthermore, the study conveys the ways most of the former forcibly recruited kept on going and today cope with ongoing war-related adversity and difficult reintegration processes without relying on psycho-social intervention. Thirty-five of the 36 women and men were forcibly recruited when they were children by the Lord's Resistance Army (LRA) from the Acholi region of northern Uganda...
July 11, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28737954/an-app-a-day-keeps-the-doctor-away-guided-education-and-training-via-smartphones-in-subthreshold-post-traumatic-stress-disorder
#2
Michael J Roy, Michelle E Costanzo, Krista B Highland, Cara Olsen, Denece Clayborne, Wendy Law
Post traumatic stress disorder (PTSD) symptoms are common in military service members (SMs), but stigma can impede treatment initiation. Smartphone applications (apps) are available anywhere, anytime, with the potential to both mitigate the impact of stigma and reduce PTSD symptom severity. We provided 144 SMs or family members, with subthreshold PTSD symptoms (PTSD Checklist [PCL] scores of 28-49), with apps promoting psychoeducation, social engagement, and relaxation and randomized them to 6 weeks of resilience enhancement (brief cognitive-behavioral session, followed by daily text messages directing app use) or a control group (daily text messages of inspirational quotes)...
July 24, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28737489/nfatc2-enhances-tumor-initiating-phenotypes-through-the-nfatc2-sox2-aldh-axis-in-lung-adenocarcinoma
#3
Zhi-Jie Xiao, Jing Liu, Si-Qi Wang, Yun Zhu, Xu-Yuan Gao, Vicky Pui-Chi Tin, Jing Qin, Jun-Wen Wang, Maria Pik Wong
Tumor initiating cells (TIC) are dynamic cancer cell subsets that display enhanced tumor functions and resilience to treatment but the mechanism of TIC induction or maintenance in lung cancer is not fully understood. In this study, we show the calcium pathway transcription factor NFATc2 is a novel regulator of lung TIC phenotypes, including tumorspheres, cell motility, tumorigenesis, as well as in vitro and in vivo responses to chemotherapy and targeted therapy. In human lung cancers, high NFATc2 expression predicted poor tumor differentiation, adverse recurrence-free and cancer-specific overall survivals...
July 24, 2017: ELife
https://www.readbyqxmd.com/read/28737175/natural-variation-of-macrophage-activation-as-disease-relevant-phenotype-predictive-of-inflammation-and-cancer-survival
#4
Konrad Buscher, Erik Ehinger, Pritha Gupta, Akula Bala Pramod, Dennis Wolf, George Tweet, Calvin Pan, Charles D Mills, Aldons J Lusis, Klaus Ley
Although mouse models exist for many immune-based diseases, the clinical translation remains challenging. Most basic and translational studies utilize only a single inbred mouse strain. However, basal and diseased immune states in humans show vast inter-individual variability. Here, focusing on macrophage responses to lipopolysaccharide (LPS), we use the hybrid mouse diversity panel (HMDP) of 83 inbred strains as a surrogate for human natural immune variation. Since conventional bioinformatics fail to analyse a population spectrum, we highlight how gene signatures for LPS responsiveness can be derived based on an Interleukin-12β and arginase expression ratio...
July 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/28736897/taking-culture-seriously-can-we-improve-the-developmental-health-and-well-being-of-australian-aboriginal-children-in-out-of-home-care
#5
S Raman, S Ruston, S Irwin, P Tran, P Hotton, S Thorne
BACKGROUND: Children in out-of-home care have well-documented health and developmental needs. Research suggests that Aboriginal children in care have unmet health and intervention needs. In metropolitan Sydney, Kari Aboriginal Resources Inc. (KARI), an Aboriginal organization, provides support to indigenous children in care, including clinical assessment and intervention. We wanted to determine the health and developmental needs of a subset of children in out-of-home care with KARI, who had been in stable care for at least a year...
July 23, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28736840/issop-position-statement-on-migrant-child-health
#6
REVIEW
(no author information available yet)
Greater numbers of children are on the move than ever before. In 2015, the number of forcibly displaced people across the globe reached 65.3 million. Of the more than 1 million migrants, asylum seekers, and refugees who arrived in Europe in 2015, nearly one third were children, and 90,000 of these children were unaccompanied. Child migrants are among the most vulnerable, even after arriving at their destination. The health of migrant children is related to their health status before their journey, the conditions during their journey and at their destination, and the physical and mental health of their caregivers...
July 23, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28736806/a-skill-set-for-supporting-displaced-children-in-psychological-recovery-after-disasters
#7
REVIEW
Betty Pfefferbaum, Anne K Jacobs, Russell T Jones, Gilbert Reyes, Karen F Wyche
Helping children, adolescents, and families displaced following a natural disaster is a daunting task made more challenging by the relatively small research base to inform services and interventions. This paper describes the current literature pertaining to intervention practices used with displaced youth. Where gaps in the literature exist, we pull from the more general research on relocation and post-disaster intervention to assist practitioners in tailoring their efforts. Specifically discussed are ways to enhance youth resilience, to help youth build new social connections and adjust to change and uncertainty while coping with trauma-related symptoms, and to meet needs through the systems in which children are embedded...
September 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28736756/advancing-the-science-of-myocardial-recovery-with-mechanical-circulatory-support-a-working-group-of-the-national-heart-lung-and-blood-institute
#8
Stavros G Drakos, Francis D Pagani, Martha S Lundberg, J Timothy Baldwin
The medical burden of heart failure (HF) has spurred interest in clinicians and scientists to develop therapies to restore the function of a failing heart. To advance this agenda, the National Heart Lung Blood Institute (NHLBI) convened a Working Group of experts on June 2-3, 2016 in Bethesda Maryland to develop recommendations for the NHLBI aimed at advancing the science of cardiac recovery in the setting of mechanical circulatory support (MCS). MSC devices effectively reduce volume and pressure overload that drives the cycle of progressive myocardial dysfunction, thereby triggering structural and functional reverse remodeling...
June 2017: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/28735767/measuring-participation-in-chronic-back-pain-patients-the-5-item-pain-disability-index
#9
Ashley B McKillop, Linda J Carroll, Bruce D Dick, Michele C Battié
BACKGROUND CONTEXT: Of the three broad outcome domains of body functions and structures, activities, and participation (e.g., engaging in valued social roles) outlined in the World Health Organization's (WHO) International Classification of Functioning, Disability and Health (ICF), it has been argued that participation is the most important to individuals, particularly those with chronic health problems. Yet, participation is not commonly measured in back pain research. PURPOSE: The aim of this study was to investigate the construct validity of a modified 5-Item Pain Disability Index (PDI) score as a measure of participation in people with chronic back pain...
July 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28735641/risk-and-resilience-brain-networks-in-treatment-resistant-schizophrenia
#10
Eleni P Ganella, Caio Seguin, Cali F Bartholomeusz, Sarah Whittle, Chad Bousman, Cassandra M J Wannan, Maria A Di Biase, Christina Phassouliotis, Ian Everall, Christos Pantelis, Andrew Zalesky
BACKGROUND: Genes, molecules and neural circuits that are associated with, or confer risk to developing schizophrenia have been studied and mapped. It is hypothesized that certain neural systems may counterbalance familial risk of schizophrenia, and thus confer resilience to developing the disorder. This study sought to identify resting-state functional brain connectivity (rs-FC) representing putative risk or resilience endophenotypes in schizophrenia. METHODS: Resting-state functional magnetic resonance imaging (rs-fMRI) was performed in 42 individuals with treatment resistant schizophrenia (TRS), 16 unaffected first-degree family members (UFM) and 42 healthy controls...
July 20, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28735591/-we-expect-seniors-to-be-able-to-prepare-and-recover-from-a-cyclone-as-well-as-younger-members-of-this-community-emergency-management-s-expectations-of-older-adults-residing-in-aging-remote-hamlets-on-australia-s-cyclone-prone-coastline
#11
Sandra Astill, Evonne Miller
OBJECTIVE: To investigate the extent to which older residents feel they can remain "self-reliant" during future natural disasters and to compare the findings with the viewpoints of local policy-makers and with those charged with caring for the elderly both on a day-to-day basis and in times of crisis. METHODS: This study used an array of non-probability snowballing techniques to seek the participation of senior citizens over the age of 65 years, emergency services officers, community health carers, and local government disaster managers located in aging, remote, coastal Australian communities vulnerable to cyclones and storm surges...
July 24, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28735391/toward-a-resilient-functional-microbiome-drought-tolerance-alleviating-microbes-for-sustainable-agriculture
#12
Venkatachalam Lakshmanan, Prasun Ray, Kelly D Craven
In recent years, the utilization of novel sequencing techniques opened a new field of research into plant microbiota and was used to explore a wide diversity of microorganisms both inside and outside of plant host tissues, i.e., the endosphere and rhizosphere, respectively. An early realization from such research was that species richness and diversity of the plant microbiome are both greater than believed even a few years ago, and soil is likely home to the most abundant and diverse microbial habitats known...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28734937/longitudinal-examination-of-resilience-after-traumatic-brain-injury-a-traumatic-brain-injury-model-systems-study
#13
Jennifer H Marwitz, Adam P Sima, Jeffrey S Kreutzer, Laura E Dreer, Thomas F Bergquist, Ross Zafonte, Douglas Johnson-Greene, Elizabeth R Felix
OBJECTIVE: To evaluate the trajectory of resilience during the first year following a moderate-severe TBI, factors associated with resilience at 3, 6 and 12-months post-injury, and changing relationships over time between resilience and other factors. DESIGN: Longitudinal analysis of an observational cohort. SETTING: Five inpatient rehabilitation centers. PARTICIPANTS: Patients with TBI (N = 195) enrolled in the resilience module of the TBI Model Systems study with data collected at 3, 6, and 12-month follow-up...
July 19, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28734859/provider-health-and-wellness
#14
REVIEW
Anil Nanda, Anita Wasan, James Sussman
Provider health and wellness is a significant issue and can impact patient care, including patient satisfaction, quality of care, medical errors, malpractice risk, as well as provider and office staff turnover and early retirement. Health and wellness encompasses various areas including burnout, depression, divorce, and suicide and affects providers of all specialties and at all levels of training. Providers deal with many everyday stresses, including electronic health records, office politics, insurance and billing issues, dissatisfied patients, and their own personal and family issues...
July 19, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28734593/unifying-research-on-social-ecological-resilience-and-collapse
#15
REVIEW
Graeme S Cumming, Garry D Peterson
Ecosystems influence human societies, leading people to manage ecosystems for human benefit. Poor environmental management can lead to reduced ecological resilience and social-ecological collapse. We review research on resilience and collapse across different systems and propose a unifying social-ecological framework based on (i) a clear definition of system identity; (ii) the use of quantitative thresholds to define collapse; (iii) relating collapse processes to system structure; and (iv) explicit comparison of alternative hypotheses and models of collapse...
July 19, 2017: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/28734167/mindfulness-practice-moderates-the-relationship-between-craving-and-substance-use-in-a-clinical-sample
#16
Matthew C Enkema, Sarah Bowen
Relapse following treatment for substance use disorders is highly prevalent, and craving has been shown to be a primary predictor of relapse. Mindfulness-Based Relapse Prevention (MBRP) is a psychosocial aftercare program integrating mindfulness and cognitive-behavioral approaches, aimed at reducing the risk and severity of relapse. Results from a recent randomized clinical trial demonstrate enhanced remission resilience for MBRP participants versus both cognitive-behavioral and treatment-as-usual controls...
June 29, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28733919/substance-use-violence-and-antiretroviral-adherence-a-latent-class-analysis-of-women-living-with-hiv-in-canada
#17
Allison Carter, Eric Abella Roth, Erin Ding, M-J Milloy, Mary Kestler, Shahab Jabbari, Kath Webster, Alexandra de Pokomandy, Mona Loutfy, Angela Kaida
We used latent class analysis to identify substance use patterns for 1363 women living with HIV in Canada and assessed associations with socio-economic marginalization, violence, and sub-optimal adherence to combination antiretroviral therapy (cART). A six-class model was identified consisting of: abstainers (26.3%), Tobacco Users (8.81%), Alcohol Users (31.9%), 'Socially Acceptable' Poly-substance Users (13.9%), Illicit Poly-substance Users (9.81%) and Illicit Poly-substance Users of All Types (9.27%). Multinomial logistic regression showed that women experiencing recent violence had significantly higher odds of membership in all substance use latent classes, relative to Abstainers, while those reporting sub-optimal cART adherence had higher odds of being members of the poly-substance use classes only...
July 21, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28733859/the-past-and-future-in-understanding-the-health-risks-of-and-responses-to-climate-variability-and-change
#18
Kristie L Ebi, Jeremy J Hess
Climate change and health was established as a formal field of endeavor in the early 1990s, with the number of publications increasing since the mid-2000s. The key findings in assessment reports from the Intergovernmental Panel on Climate Change in 1995, 2001, 2007, and 2014 indicate the progress in understanding the magnitude and pattern of the health risks of a changing climate. The assessments maintained a similar structure, focusing on assessing the state of knowledge of individual climate-sensitive health outcomes, with confidence in the key findings tending to increase over time with greater understanding...
July 21, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28733297/behind-the-smile-qualitative-study-of-caregivers-anguish-and-management-responses-while-caring-for-someone-living-with-heart-failure
#19
Jennifer Wingham, Julia Frost, Nicky Britten
BACKGROUND: Caregivers support self-management in heart failure but often experience stress, anxiety and ill health as a result of providing care. AIMS: 1. To identify the factors that contribute to the experience of anguish.2. To understand how caregivers learn to live with what is frequently a challenging and demanding role. METHODS: Individual interviews with caregivers who had been caring for someone with heart failure for a minimum of 6 months...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28732806/artemisia-annua-dried-leaf-tablets-treated-malaria-resistant-to-act-and-i-v-artesunate-case-reports
#20
Nsengiyumva Bati Daddy, Luc Malemo Kalisya, Pascal Gisenya Bagire, Robert L Watt, Melissa J Towler, Pamela J Weathers
BACKGROUND: Dried leaf Artemisia annua (DLA) has shown efficacy against Plasmodium sp. in rodent studies and in small clinical trials. Rodent malaria also showed resiliency against the evolution of artemisinin drug resistance. PURPOSE: This is a case report of a last resort treatment of patients with severe malaria who were responding neither to artemisinin combination therapy (ACT) nor i.v. artesunate. STUDY DESIGN: Of many patients treated with ACTs and i...
August 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
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