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Frankincense

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https://www.readbyqxmd.com/read/29316908/efficacy-and-safety-of-curcumin-and-its-combination-with-boswellic-acid-in-osteoarthritis-a-comparative-randomized-double-blind-placebo-controlled-study
#1
Armine Haroyan, Vahan Mukuchyan, Nana Mkrtchyan, Naira Minasyan, Srbuhi Gasparyan, Aida Sargsyan, Mikael Narimanyan, Areg Hovhannisyan
BACKGROUND: The aim of this clinical trial was to assess the efficacy and safety of curcuminoid complex extract from turmeric rhizome with turmeric volatile oil (CuraMed®) and its combination with boswellic acid extract from Indian frankincense root (Curamin®) vs placebo for the treatment of 40- to 70-year-old patients with osteoarthritis (OA). METHODS: The effects of CuraMed® 500-mg capsules (333 mg curcuminoids) and Curamin® 500-mg capsules (350 mg curcuminoids and 150 mg boswellic acid) taken orally three times a day for 12 weeks in 201 patients was investigated in a three-arm, parallel-group, randomized, double-blinded, placebo-controlled trial...
January 9, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29275327/standardised-frankincense-extract-new-possible-therapeutic-option-for-patients-with-relapsing-remitting-multiple-sclerosis
#2
EDITORIAL
Francesco Patti
No abstract text is available yet for this article.
December 23, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29248894/a-standardised-frankincense-extract-reduces-disease-activity-in-relapsing-remitting-multiple-sclerosis-the-saba-phase-iia-trial
#3
Klarissa Hanja Stürner, Jan-Patrick Stellmann, Jan Dörr, Friedemann Paul, Tim Friede, Sven Schammler, Stefanie Reinhardt, Susanne Gellissen, Gainet Weissflog, Tobias Djamsched Faizy, Oliver Werz, Sabine Fleischer, Lea A I Vaas, Frank Herrmann, Ole Pless, Roland Martin, Christoph Heesen
OBJECTIVE: To investigate whether oral administration of a standardised frankincense extract (SFE) is safe and reduces disease activity in patients with relapsing-remitting multiple sclerosis (RRMS). METHODS: We performed an investigator-initiated, bicentric phase IIa, open-label, baseline-to-treatment pilot study with an oral SFE in patients with RRMS (NCT01450124). After a 4-month baseline observation phase, patients were treated for 8 months with an option to extend treatment for up to 36 months...
December 16, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29192445/-effects-of-frankincense-and-myrrh-essential-oil-on-transdermal-absorption-of-ferulic-acid-in-chuanxiong
#4
Yong-Mei Guan, Ling Tao, Xiao-Fang Zhu, Zhen-Zhong Zang, Chen Jin, Li-Hua Chen
The aim of this paper was to explore the effects of Frankincense and Myrrh essential oil on transdermal absorption, and investigate the mechanism of permeation on the microstructure and molecular structure of stratum corneum. Through the determination of stratum corneum/medium partition coefficient of ferulicacid in Chuanxiong influenced by Frankincense and Myrrh essential oil, the effects of volatile oil of frankincense and Myrrh on the the microscopic and molecular structure of stratum corneum were explored by observation of skin stratum corneum structure under scanning electron microscopy, and investigation of frankincense and myrrh essential oil effects on the molecular structure of keratin and lipids in stratum corneum under Fourier transform infrared spectroscopy...
September 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29115548/frankincense-pine-needle-and-geranium-essential-oils-suppress-tumor-progression-through-the-regulation-of-the-ampk-mtor-pathway-in-breast-cancer
#5
Peng Ren, Xiang Ren, Lei Cheng, Lixin Xu
BC (BC), as the most common malignancy in women worldwide, is associated with high morbidity and mortality. However, chemoresistance and toxicity are the main causes that limit the success of treatment in aggressive BC cases. Thus, there is a vital need to identify and develop novel therapeutic agents. Frankincense, pine needle and geranium essential oils have been reported to play critical biological activities in cancer. However, to the best of our knowledge whether frankincense, pine needle and geranium essential oils have any effect on the progression of BC in MCF-7 cells remains unclear...
November 1, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29109091/transcriptomic-profiling-of-mda-mb-231-cells-exposed-to-boswellia-serrata-and-3-o-acetyl-b-boswellic-acid-er-upr-mediated-programmed-cell-death
#6
REVIEW
Elizabeth A Mazzio, Charles A Lewis, Karam F A Soliman
BACKGROUND/AIM: Triple-negative breast cancer (TNBC) is characterized by the absence of hormone receptors (estrogen, progesterone and human epidermal growth factor receptor-2) and a relatively poor prognosis due to inefficacy of hormone receptor-based chemotherapies. It is imperative that we continue to explore natural products with potential to impede growth and metastasis of TNBC. In this study, we screened over 1,000 natural products for capacity to induce cell death in TNBC (MDA-MB -231) cells...
November 2017: Cancer Genomics & Proteomics
https://www.readbyqxmd.com/read/29053752/rhizospheric-microbial-communities-associated-with-wild-and-cultivated-frankincense-producing-boswellia-sacra-tree
#7
Abdul Latif Khan, Sajjad Asaf, Ahmed Al-Rawahi, In-Jung Lee, Ahmed Al-Harrasi
Boswellia sacra, a frankincense producing endemic tree, has been well known for its cultural, religious and economic values. However, the tree has been least explored for the associated microsymbiota in the rhizosphere. The current study elucidates the fungal and bacterial communities of the rhizospheric regions of the wild and cultivated B. sacra tree populations through next generation sequencing. The sequence analysis showed the existence of 1006±8.9 and 60.6±3.1 operational taxonomic unit (OTUs) for bacterial and fungal communities respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28959837/-effects-of-frankincense-and-myrrh-essential-oil-on-transdermal-absorption-in-vitro-of-chuanxiong-and-penetration-mechanism-of-skin-blood-flow
#8
Xiao-Fang Zhu, Jing Luo, Yong-Mei Guan, Ya-Ting Yu, Chen Jin, Wei-Feng Zhu, Hong-Ning Liu
The aim of this paper was to explore the effects of Frankincense and Myrrh essential oil on transdermal absorption in vitro of Chuanxiong, and to investigate the possible penetration mechanism of their essential oil from the perspective of skin blood perfusion changes. Transdermal tests were performed in vitro with excised mice skin by improved Franz diffusion cells. The cumulative penetration amounts of ferulic acid in Chuanxiong were determined by HPLC to investigate the effects of Frankincense and Myrrh essential oil on transdermal permeation properties of Chuanxiong...
February 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929699/-transmission-and-development-of-foreign-medicinal-materials-in-the-tang-and-song-dynasties
#9
Meng-Hua Wu, Zhong-Zhen Zhao, Hui Cao
Many foreign medicinal materials that were imported to China via the Silk Road and maritime trade have enriched Chinese medicine. Imported foreign medicines reached a high point by the Tang and Song Dynasties, particularly in the case of aromatic medicines, which supplemented domestic Chinese aromatics and were widely employed in official dispensaries in the Song Dynasty. This study investigated historical records related to imported Chinese medicines in the Tang and Song periods, focusing on their varieties, quantity, use, and localization trends...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28740739/a-combined-water-extract-of-frankincense-and-myrrh-alleviates-neuropathic-pain-in-mice-via-modulation-of-trpv1
#10
Danyou Hu, Changming Wang, Fengxian Li, Shulan Su, Niuniu Yang, Yan Yang, Chan Zhu, Hao Shi, Lei Yu, Xiao Geng, Leying Gu, Xiaolin Yuan, Zhongli Wang, Guang Yu, Zongxiang Tang
Frankincense and myrrh are widely used in clinics as a pair of herbs to obtain a synergistic effect for relieving pain. To illuminate the analgesia mechanism of frankincense and myrrh, we assessed its effect in a neuropathic pain mouse model. Transient receptor potential vanilloid 1 (TRPV1) plays a crucial role in neuropathic pain and influences the plasticity of neuronal connectivity. We hypothesized that the water extraction of frankincense and myrrh (WFM) exerted its analgesia effect by modulating the neuronal function of TRPV1...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28738439/terpenoids-from-the-oleo-gum-resin-of-boswellia-serrata-and-their-antiplasmodial-effects-in-vitro
#11
Hippolyt L Greve, Marcel Kaiser, Reto Brun, Thomas J Schmidt
In the course of our ongoing search for new natural products as leads against protozoal diseases, the dichloromethane extract of Indian frankincense, the oleo-gum-resin obtained from Boswellia serrata, showed in vitro activity against Plasmodium falciparum. Bioactivity-guided fractionation led to the isolation of eight diterpenes: (1S,3E,7E,11R)-verticilla-3,7,12(18)-triene (1), cembrene A (2), serratol (3), 1S,3E,7R,8R,11E-7,8-epoxy-cembra-3,11-dien-1-ol (4), incensole oxide (5), rel (1S,3R,7E,11S,12R)-1,12-epoxy-4-methylenecembr-7-ene-3, 11-diol (6), isoincensole oxide (7), and isodecaryiol (8)...
October 2017: Planta Medica
https://www.readbyqxmd.com/read/28633539/a-survey-on-chemical-constituents-and-indications-of-aromatic-waters-soft-drinks-hydrosols-used-in-persian-nutrition-culture-and-folk-medicine-for-neurological-disorders-and-mental-health
#12
Azadeh Hamedi, Ardalan Pasdaran, Zahra Zebarjad, Mahmoodreza Moein
In Persian nutrition culture, drinking aromatic waters (hydrosols, distillate) has a long history as functional beverages or therapeutic remedies. The co-distilled water with essential oils, which contains partial amounts of more water-soluble volatile compounds are diluted and used as beverages. Since the solubility of volatile components is different in water, the overall composition, and thus the biological activities of aromatic waters seem to be different from the essential oils they were co-distilled with...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28549801/methanolic-extract-of-boswellia-serrata-exhibits-anti-cancer-activities-by-targeting-microsomal-prostaglandin-e-synthase-1-in-human-colon-cancer-cells
#13
Tayebeh Ranjbarnejad, Massoud Saidijam, Shirin Moradkhani, Rezvan Najafi
BACKGROUND: Colorectal cancer (CRC) is the most common cancer. A proper method to reduce mortality of CRC is chemoprevention to prevent initiation and promotion of intestinal tumorgenesis. One of the promising and developing chemopreventive agents is natural compounds found in plants. Frankincense, the resin extract from the Boswellia specious, has been used in traditional and modern medicine for treating various diseases with very minimal side effects. In the current study, we investigated the anti-cancer activity of methanolic extract of Boswellia serrata (B...
May 24, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28437753/p-gp-modulatory-acetyl-11-keto-%C3%AE-boswellic-acid-based-nanoemulsified-carrier-system-for-augmented-oral-chemotherapy-of-docetaxel
#14
Gitu Pandey, Naresh Mittapelly, Guru Raghavendra Valicherla, Ravi Prakash Shukla, Shweta Sharma, Venkatesh Teja Banala, Sandeep Urandur, Arun Kumar Jajoriya, Kalyan Mitra, D P Mishra, J R Gayen, P R Mishra
In spite of being a very potent and promising drug against many types of cancer, docetaxel suffers the disadvantage of low solubility and poor bioavailability rendering it unsuitable for oral administration. Also, the available marketed formulation for intravenous administration has its inherent drawbacks owing to the presence of polysorbate 80. Here, we exploited the anticancer and P-gp inhibitory potential of naturally occurring frankincense oil to fabricate a stable docetaxel loaded nanoemulsified carrier system for oral delivery...
April 15, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28386311/antioxidant-and-ex-vivo-immune-system-regulatory-properties-of-boswellia-serrata-extracts
#15
Daniela Beghelli, Gloria Isani, Paola Roncada, Giulia Andreani, Onelia Bistoni, Martina Bertocchi, Giulio Lupidi, Alessia Alunno
Boswellia serrata (BS) is an important traditional medicinal plant that currently represents an interesting topic for pharmaceutical research since it possesses several pharmacological properties (e.g., anti-inflammatory, antimicrobial, and antitumour). The safety and versatility of this dietary supplement should allow for its use in numerous pathological conditions; however the quality of the extracts needs to be standardized to increase the clinical success rate resulting from its use. In the present study, different commercially available B...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28381769/a-review-of-anti-inflammatory-terpenoids-from-the-incense-gum-resins-frankincense-and-myrrh
#16
Toshio Morikawa, Hisashi Matsuda, Masayuki Yoshikawa
Frankincense and myrrh have been used as incense in religious and cultural ceremonies since the beginning of written history. Their common medicinal properties are used in the treatment for inflammatory conditions, some cancerous diseases, and wound healing. In the course of our characterization of the anti-inflammatory constituents from frankincense and myrrh, several terpenoid constituents were found to inhibit nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Here we review the structure of those terpenoid constituents from the gum resins of frankincense and myrrh and evaluate their anti-inflammatory effects by their nitric oxide production inhibitory activity...
August 1, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28326753/effects-of-essential-oil-exposure-on-salivary-estrogen-concentration-in-perimenopausal-women
#17
Kazuyuki Shinohara, Hirokazu Doi, Chizu Kumagai, Erika Sawano, Wataru Tarumi
OBJECTIVES: The menopausal transition is the time from the onset of menstrual changes until one year after the final menstrual period. During this phase, perimenopausal women experience a variety of health-related symptoms, which seemingly derive from declining level of estrogen secretion. It has long been recognized that some essential oils have the efficacy of alleviating menopausal symptoms. On the basis of this, it is possible that these essential oils have the potency to facilitate estrogen secretion in women...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28278495/antioxidant-supplements-and-gastrointestinal-diseases-a-critical-appraisal
#18
Islam Khan, Sue E Samson, Ashok Kumar Grover
The gastrointestinal tract digests and absorbs dietary nutrients, protects the body against physical and chemical damage from contents in its lumen, provides immunity against external antigens, and keeps an optimum environment for the gut microbiota. These functions cannot be performed normally in several diseases of which the following are discussed here: irritable bowel syndrome and inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Because these diseases are associated with oxidative stress, a host of antioxidant supplements are used for maintenance and recovery of the gut functions...
2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/27975612/search-for-new-antiprotozoal-leads-in-oleo-gum-resins-from-plants-of-the-family-burseraceae-indian-frankincense-and-myrrh
#19
H L Greve, M Kaiser, R Brun, T J Schmidt
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27975355/-christmas-from-an-allergist-s-perspective
#20
REVIEW
Bettina Wedi
The customs and traditions associated with Christmas may result in allergic reactions to allergens that are typical for this period. On the one hand the rise in prevalence of allergic diseases has continued in the industrialized world for the last decades and allergies are regarded as widespread diseases. On the other hand the 21th century is a time of "allergy delusion". This review summarizes the facts about allergic reactions to Christmas typical decoration, food and behavior. Taken together, allergic reactions to Christmas tree, poinsettia, Christmas cactus, perfumed candles, Christmas typical food, common gifts like mobile phones and laptops, frankincense, myrrh and pollens have been described but in very rare instances...
December 2016: Deutsche Medizinische Wochenschrift
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