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Frankincense

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https://www.readbyqxmd.com/read/28633539/a-survey-on-chemical-constituents-and-indications-of-aromatic-waters-soft-drinks-hydrosols-used-in-persian-nutrition-culture-and-folk-medicine-for-neurological-disorders-and-mental-health
#1
Azadeh Hamedi, Ardalan Pasdaran, Zahra Zebarjad, Mahmoodreza Moein
In Persian nutrition culture, drinking aromatic waters (hydrosols, distillate) has a long history as functional beverages or therapeutic remedies. The co-distilled water with essential oils, which contains partial amounts of more water-soluble volatile compounds are diluted and used as beverages. Since the solubility of volatile components is different in water, the overall composition, and thus the biological activities of aromatic waters seem to be different from the essential oils they were co-distilled with...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28549801/methanolic-extract-of-boswellia-serrata-exhibits-anti-cancer-activities-by-targeting-microsomal-prostaglandin-e-synthase-1-in-human-colon-cancer-cells
#2
Tayebeh Ranjbarnejad, Massoud Saidijam, Shirin Moradkhani, Rezvan Najafi
BACKGROUND: Colorectal cancer (CRC) is the most common cancer. A proper method to reduce mortality of CRC is chemoprevention to prevent initiation and promotion of intestinal tumorgenesis. One of the promising and developing chemopreventive agents is natural compounds found in plants. Frankincense, the resin extract from the Boswellia specious, has been used in traditional and modern medicine for treating various diseases with very minimal side effects. In the current study, we investigated the anti-cancer activity of methanolic extract of Boswellia serrata (B...
May 24, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28437753/p-gp-modulatory-acetyl-11-keto-%C3%AE-boswellic-acid-based-nanoemulsified-carrier-system-for-augmented-oral-chemotherapy-of-docetaxel
#3
Gitu Pandey, Naresh Mittapelly, Guru Raghavendra Valicherla, Ravi Prakash Shukla, Shweta Sharma, Venkatesh Teja Banala, Sandeep Urandur, Arun Kumar Jajoriya, Kalyan Mitra, D P Mishra, J R Gayen, P R Mishra
In spite of being a very potent and promising drug against many types of cancer, docetaxel suffers the disadvantage of low solubility and poor bioavailability rendering it unsuitable for oral administration. Also, the available marketed formulation for intravenous administration has its inherent drawbacks owing to the presence of polysorbate 80. Here, we exploited the anticancer and P-gp inhibitory potential of naturally occurring frankincense oil to fabricate a stable docetaxel loaded nanoemulsified carrier system for oral delivery...
April 15, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28386311/antioxidant-and-ex-vivo-immune-system-regulatory-properties-of-boswellia-serrata-extracts
#4
Daniela Beghelli, Gloria Isani, Paola Roncada, Giulia Andreani, Onelia Bistoni, Martina Bertocchi, Giulio Lupidi, Alessia Alunno
Boswellia serrata (BS) is an important traditional medicinal plant that currently represents an interesting topic for pharmaceutical research since it possesses several pharmacological properties (e.g., anti-inflammatory, antimicrobial, and antitumour). The safety and versatility of this dietary supplement should allow for its use in numerous pathological conditions; however the quality of the extracts needs to be standardized to increase the clinical success rate resulting from its use. In the present study, different commercially available B...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28381769/a-review-of-anti-inflammatory-terpenoids-from-the-incense-gum-resins-frankincense-and-myrrh
#5
Toshio Morikawa, Hisashi Matsuda, Masayuki Yoshikawa
Frankincense and myrrh have been used as incense in religious and cultural ceremonies since the beginning of written history. Their common medicinal properties are used in the treatment for inflammatory conditions, some cancerous diseases, and wound healing. In the course of our characterization of the anti-inflammatory constituents from frankincense and myrrh, several terpenoid constituents were found to inhibit nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Here we review the structure of those terpenoid constituents from the gum resins of frankincense and myrrh and evaluate their anti-inflammatory effects by their nitric oxide production inhibitory activity...
April 4, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28326753/effects-of-essential-oil-exposure-on-salivary-estrogen-concentration-in-perimenopausal-women
#6
Kazuyuki Shinohara, Hirokazu Doi, Chizu Kumagai, Erika Sawano, Wataru Tarumi
OBJECTIVES: The menopausal transition is the time from the onset of menstrual changes until one year after the final menstrual period. During this phase, perimenopausal women experience a variety of health-related symptoms, which seemingly derive from declining level of estrogen secretion. It has long been recognized that some essential oils have the efficacy of alleviating menopausal symptoms. On the basis of this, it is possible that these essential oils have the potency to facilitate estrogen secretion in women...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28278495/antioxidant-supplements-and-gastrointestinal-diseases-a-critical-appraisal
#7
Islam Khan, Sue E Samson, Ashok Kumar Grover
The gastrointestinal tract digests and absorbs dietary nutrients, protects the body against physical and chemical damage from contents in its lumen, provides immunity against external antigens, and keeps an optimum environment for the gut microbiota. These functions cannot be performed normally in several diseases of which the following are discussed here: irritable bowel syndrome and inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Because these diseases are associated with oxidative stress, a host of antioxidant supplements are used for maintenance and recovery of the gut functions...
2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/27975612/search-for-new-antiprotozoal-leads-in-oleo-gum-resins-from-plants-of-the-family-burseraceae-indian-frankincense-and-myrrh
#8
H L Greve, M Kaiser, R Brun, T J Schmidt
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27975355/-christmas-from-an-allergist-s-perspective
#9
REVIEW
Bettina Wedi
The customs and traditions associated with Christmas may result in allergic reactions to allergens that are typical for this period. On the one hand the rise in prevalence of allergic diseases has continued in the industrialized world for the last decades and allergies are regarded as widespread diseases. On the other hand the 21th century is a time of "allergy delusion". This review summarizes the facts about allergic reactions to Christmas typical decoration, food and behavior. Taken together, allergic reactions to Christmas tree, poinsettia, Christmas cactus, perfumed candles, Christmas typical food, common gifts like mobile phones and laptops, frankincense, myrrh and pollens have been described but in very rare instances...
December 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27765357/a-single-dose-randomized-cross-over-two-way-open-label-study-for-comparing-the-absorption-of-boswellic-acids-and-its-lecithin-formulation
#10
RANDOMIZED CONTROLLED TRIAL
Antonella Riva, Paolo Morazzoni, Christian Artaria, Pietro Allegrini, Jürgen Meins, Daniele Savio, Giovanni Appendino, Manfred Schubert-Zsilavecz, Mona Abdel-Tawab
BACKGROUND: The oral administration of the gum resin extracts of Indian frankincense (Boswellia serrata Roxb. ex Colebr) results in very low plasma concentrations of boswellic acids (BAs), being far below the pharmacologically active concentrations required in vitro for anti-inflammatory activity. For that reason the use of Indian frankincense in clinical practice and pharmaceutical development has substantially lagged behind. Recently the application of new formulation technologies resulted in a formulation of frankincense extract with lecithin, which revealed improved absorption and tissue penetration of BAs in a rodent study, leading for the first time to plasma concentrations of BAs in the range of their anti-inflammatory activity...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27699963/the-cis-and-trans-olibanic-acids-key-odorants-of-frankincense
#11
Céline Cerutti-Delasalle, Mohamed Mehiri, Cecilia Cagliero, Patrizia Rubiolo, Carlo Bicchi, Uwe J Meierhenrich, Nicolas Baldovini
Frankincense (olibanum) is one of the oldest aromatic materials used by humans, but the key molecular constituents contributing to its characteristic odor remained unknown. Reported herein is the discovery that (1S,2S)-(+)-trans- and (1S,2R)-(+)-cis-2-octylcyclopropyl-1-carboxylic acids are highly potent and substantive odorants occurring in ppm amounts in all of the frankincense samples analyzed, even those showing radically different volatile compositions. These cyclopropyl-derived acids provide the very characteristic old churchlike endnote of the frankincense odor...
October 24, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27531547/cancer-chemopreventive-effects-of-boswellia-sacra-gum-resin-hydrodistillates-on-invasive-urothelial-cell-carcinoma-report-of-a-case
#12
Ding Xia, Weiwei Lou, Kar-Ming Fung, Cole L Wolley, Mahmoud M Suhail, Hsueh-Kung Lin
A 52-year-old Hispanic male presented with hematuria and was later diagnosed with a large invasive high-grade urothelial cell carcinoma (UCC) of the urinary bladder, but with ambiguous pT1/pT2 staging regarding musclaris propria invasion by UCC. The conventional treatment including radical cystoprostatectomy followed by neoadjuvant chemotherapy with or without radiation therapy was presented. The patient decided to delay the standard therapy until a later stage, but elected to go through transurethral resection of bladder tumor (TURBT) without Bacillus Calmette-Guérin instillation...
August 16, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27516988/therapeutic-effect-of-frankincense-in-a-rat-model-of-alzheimer-s-disease
#13
Siamak Beheshti, Rezvan Aghaie
OBJECTIVE: Frankincense improves memory in different models of learning. However, its influence on models of Alzheimer's disease (AD) has not been studied widely. In the present study, the therapeutic effect of frankincense was evaluated in a model of AD induced by i.c.v administration of streptozotocin. MATERIALS AND METHODS: Under stereotaxic surgery, two guide cannulas were implanted in the lateral ventricles of adult male Wistar rats weighing 230-270 g. One group received streptozotocin (1...
July 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27516690/fingerprints-pharmaceutical-and-radical-scavenging-activity-evaluation-of-an-alzheimer-targeted-herbal-preparation
#14
Farid Dabaghian, Sedigheh Khademian, Amir Azadi, Mohammad Zarshenas
BACKGROUND: As the most common form of dementia, Alzheimer disease is characterized by progressive loss of memory and deterioration of cognitive functions. It is predicted that about 75.63 million people would suffer from dementia by 2030. Apart from conventional remedies, the application of herbal medicines is on the rise. There are numerous natural medicaments reported in the traditional manuscript of Persian medicine. Accordingly, in the present study, the intended remedy was selected and an appropriate pharmacognostical and pharmaceutical evaluations were performed...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27493682/simultaneous-quantification-of-triterpenoic-acids-by-high-performance-liquid-chromatography-method-in-the-extracts-of-gum-resin-of-boswellia-serrata-obtained-by-different-extraction-techniques
#15
Neha Sharma, Vikram Bhardwaj, Samar Singh, Sheikh Abid Ali, D K Gupta, Satya Paul, Naresh K Satti, Suresh Chandra, Mahendra K Verma
BACKGROUND: Boswellia serrata, also known as Indian frankincense is a commercially important medicinal plant which has been used for hundreds of years as an Ayurvedic medicine for the attempted treatment of arthritis. It contains naturally occurring triterpenoic acids, called as boswellic acids (BA's). RESULTS: A highly reproducible High performance liquid chromatography-ultraviolet diode array detection (HPLC-UV-DAD) method was developed for the simultaneous determination and quantitative analysis of eight major triterpenoic acids in Boswellia serrata gum resin obtained by different extraction techniques...
2016: Chemistry Central Journal
https://www.readbyqxmd.com/read/27359330/endophytic-fungi-from-frankincense-tree-improves-host-growth-and-produces-extracellular-enzymes-and-indole-acetic-acid
#16
Abdul Latif Khan, Ahmed Al-Harrasi, Ahmed Al-Rawahi, Zainab Al-Farsi, Aza Al-Mamari, Muhammad Waqas, Sajjad Asaf, Ali Elyassi, Fazal Mabood, Jae-Ho Shin, In-Jung Lee
Boswellia sacra, an economically important frankincense-producing tree found in the desert woodlands of Oman, is least known for its endophytic fungal diversity and the potential of these fungi to produce extracellular enzymes and auxins. We isolated various fungal endophytes belonging to Eurotiales (11.8%), Chaetomiaceae (17.6%), Incertae sadis (29.5%), Aureobasidiaceae (17.6%), Nectriaceae (5.9%) and Sporomiaceae (17.6%) from the phylloplane (leaf) and caulosphere (stem) of the tree. Endophytes were identified using genomic DNA extraction, PCR amplification and sequencing the internal transcribed spacer regions, whereas a detailed phylogenetic analysis of the same gene fragment was made with homologous sequences...
2016: PloS One
https://www.readbyqxmd.com/read/27352042/neuroactive-and-anti-inflammatory-frankincense-cembranes-a-structure-activity-study
#17
Federica Pollastro, Samantha Golin, Giuseppina Chianese, Masteria Yunovilsa Putra, Aniello Schiano Moriello, Luciano De Petrocellis, Victor García, Eduardo Munoz, Orazio Taglialatela-Scafati, Giovanni Appendino
An expeditious isolation method for the cembrane diterpene alcohols incensol (1a) and serratol (2) has been developed from respectively African and Indian frankincense. The two native alcohols and a series of semisynthetic derivatives of incensol were evaluated for transient receptor potential vanilloid 3 (TRPV3) activation and the inhibition of NF-κB, the putative molecular targets underlying the psychotropic and anti-inflammatory activities of incensol acetate (IA, 1b). Serratol (2) was the most potent TRPV3 activator, outperforming by 2 orders of magnitude the reference agonist thymol and by 1 order of magnitude incensol acetate (1b)...
July 22, 2016: Journal of Natural Products
https://www.readbyqxmd.com/read/27313767/alantolactone-induces-apoptosis-of-human-cervical-cancer-cells-via-reactive-oxygen-species-generation-glutathione-depletion-and-inhibition-of-the-bcl-2-bax-signaling-pathway
#18
Yan Jiang, Hanjie Xu, Jiafei Wang
Alantolactone is the active ingredient in frankincense, and is extracted from the dry root of elecampane. It has a wide variety of uses, including as an insect repellent, antibacterial, antidiuretic, analgesic and anticancer agent. In addition, alantolactone induces apoptosis of human cervical cancer cells, however, its mechanism of action remains to be elucidated. Therefore, the present study investigated whether alantolactone was able to induce apoptosis of human cervical cancer cells, and its potential mechanisms of action were analyzed...
June 2016: Oncology Letters
https://www.readbyqxmd.com/read/27200097/the-in-vitro-and-in-vivo-wound-healing-properties-of-the-chinese-herbal-medicine-jinchuang-ointment
#19
Tsung-Jung Ho, Shinn-Jong Jiang, Guang-Huey Lin, Tzong Shiun Li, Lih-Ming Yiin, Jai-Sing Yang, Ming-Chuan Hsieh, Chun-Chang Wu, Jaung-Geng Lin, Hao-Ping Chen
"Jinchuang ointment" is a traditional Chinese herbal medicine complex for treatment of incised wounds. For more than ten years, it has been used at China Medical University Hospital (Taichung, Taiwan) for the treatment of diabetic foot infections and decubitus ulcers. Three different cases are presented in this study. "Jinchuang" ointment is a mixture of natural product complexes from nine different components, making it difficult to analyze its exact chemical compositions. To further characterize the herbal ingredients used in this study, the contents of reference standards present in a subset of the ointment ingredients (dragon's blood, catechu, frankincense, and myrrh) were determined by HPLC...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27143985/effect-of-frankincense-extract-on-nerve-recovery-in-the-rat-sciatic-nerve-damage-model
#20
Xiaowen Jiang, Jun Ma, Qingwei Wei, Xinxin Feng, Lu Qiao, Lin Liu, Binqing Zhang, Wenhui Yu
This study investigated the effect of frankincense extract on peripheral nerve regeneration in a crush injury rat model. Forty-eight Sprague-Dawley rats were randomly divided into four groups: control and frankincense extract low-, medium-, and high-dose groups. At days 7, 14, 21, and 28 following the surgery, nerve regeneration and functional recovery were evaluated using the sciatic functional index (SFI), expression of GAP-43, and the proliferation of Schwann cells (SCs) in vivo and in vitro. At day 7, the SFI in the frankincense extract high-dose group was significantly improved compared with the control group...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
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