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https://www.readbyqxmd.com/read/28910997/paediatric-nuclear-medicine-imaging
#1
Lorenzo Biassoni, Marina Easty
Background: Nuclear medicine imaging explores tissue viability and function by using radiotracers that are taken up at cellular level with different mechanism. This imaging technique can also be used to assess blood flow and transit through tubular organs. Nuclear medicine imaging has been used in paediatrics for decades and this field is continuously evolving. Sources of data: The data presented comes from clinical experience and some milestone papers on the subject...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28894304/quantification-of-brain-cholinergic-denervation-in-alzheimer-s-disease-using-pet-imaging-with-18-f-feobv
#2
M Aghourian, C Legault-Denis, J-P Soucy, P Rosa-Neto, S Gauthier, A Kostikov, P Gravel, M-A Bédard
(18)F-fluoroethoxybenzovesamicol (FEOBV) is a new PET radiotracer that binds to the vesicular acetylcholine transporter. In both animals and healthy humans, FEOBV was found sensitive and reliable to characterize presynaptic cholinergic nerve terminals in the brain. It has been used here for we believe the first time in patients with Alzheimer's disease (AD) to quantify brain cholinergic losses. The sample included 12 participants evenly divided in healthy subjects and patients with AD, all assessed with the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) cognitive scales...
September 12, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28877513/predicting-functional-neuroanatomical-maps-from-fusing-brain-networks-with-genetic-information
#3
REVIEW
Florian Ganglberger, Joanna Kaczanowska, Josef M Penninger, Andreas Hess, Katja Bühler, Wulf Haubensak
Functional neuroanatomical maps provide a mesoscale reference framework for studies from molecular to systems neuroscience and psychiatry. The underlying structure-function relationships are typically derived from functional manipulations or imaging approaches. Although highly informative, these are experimentally costly. The increasing amount of publicly available brain and genetic data offers a rich source that could be mined to address this problem computationally. Here, we developed an algorithm that fuses gene expression and connectivity data with functional genetic meta data and exploits cumulative effects to derive neuroanatomical maps related to multi-genic functions...
September 3, 2017: NeuroImage
https://www.readbyqxmd.com/read/28870688/-what-do-virtual-reality-tools-bring-to-child-and-adolescent-psychiatry
#4
S Bioulac, E de Sevin, P Sagaspe, A Claret, P Philip, J A Micoulaud-Franchi, M P Bouvard
Virtual reality is a relatively new technology that enables individuals to immerse themselves in a virtual world. It offers several advantages including a more realistic, lifelike environment that may allow subjects to "forget" they are being assessed, allow a better participation and an increased generalization of learning. Moreover, the virtual reality system can provide multimodal stimuli, such as visual and auditory stimuli, and can also be used to evaluate the patient's multimodal integration and to aid rehabilitation of cognitive abilities...
September 1, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28859565/neuroplasticity-and-the-brain-connectome-what-can-jean-talairach-s-reflections-bring-to-modern-psychosurgery
#5
Pierre Bourdillon, Caroline Apra, Marc Lévêque, Fabien Vinckier
Contrary to common psychosurgical practice in the 1950s, Dr. Jean Talairach had the intuition, based on clinical experience, that the brain connectome and neuroplasticity had a role to play in psychosurgery. Due to the remarkable progress of pharmacology at that time and to the technical limits of neurosurgery, these concepts were not put into practice. Currently, these concepts are being confirmed by modern techniques such as neuroimaging and computational neurosciences, and could pave the way for therapeutic innovation in psychiatry...
September 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28838470/computational-psychiatry-embracing-uncertainty-and-focusing-on-individuals-not-averages
#6
Adam M Chekroud, Chadrick E Lane, David A Ross
No abstract text is available yet for this article.
September 15, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28838467/a-formal-valuation-framework-for-emotions-and%C3%A2-their-control
#7
REVIEW
Quentin J M Huys, Daniel Renz
Computational psychiatry aims to apply mathematical and computational techniques to help improve psychiatric care. To achieve this, the phenomena under scrutiny should be within the scope of formal methods. As emotions play an important role across many psychiatric disorders, such computational methods must encompass emotions. Here, we consider formal valuation accounts of emotions. We focus on the fact that the flexibility of emotional responses and the nature of appraisals suggest the need for a model-based valuation framework for emotions...
September 15, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28838466/theory-based-computational-psychiatry
#8
Tiago V Maia, Quentin J M Huys, Michael J Frank
No abstract text is available yet for this article.
September 15, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28794897/uncovering-capgras-delusion-using-a-large-scale-medical-records-database
#9
Vaughan Bell, Caryl Marshall, Zara Kanji, Sam Wilkinson, Peter Halligan, Quinton Deeley
BACKGROUND: Capgras delusion is scientifically important but most commonly reported as single case studies. Studies analysing large clinical records databases focus on common disorders but none have investigated rare syndromes. AIMS: Identify cases of Capgras delusion and associated psychopathology, demographics, cognitive function and neuropathology in light of existing models. METHOD: Combined computational data extraction and qualitative classification using 250 000 case records from South London and Maudsley Clinical Record Interactive Search (CRIS) database...
July 2017: BJPsych Open
https://www.readbyqxmd.com/read/28755996/receptor-visualization-and-the-atomic-bomb-a-historical-account-of-the-development-of-the-chemical-neuroanatomy-of-receptors-for-neurotransmitters-and-drugs-during-the-cold-war
#10
REVIEW
J M Palacios, G Mengod
This is a historical account of how receptors for neurotransmitters and drugs got to be seen at the regional, cellular, and subcellular levels in brain, in the years going from the end of the World War II until the collapse of the Soviet Union, the Cold War (1945-1991). The realization in the US of the problem of mental health care, as a consequence of the results of medical evaluation for military service during the war, let the US Government to act creating among other things the National Institute for Mental Health (NIMH)...
July 26, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28735692/network-psychiatry-computational-methods-to-understand-the-complexity-of-psychiatric-disorders
#11
EDITORIAL
Glenn N Saxe
No abstract text is available yet for this article.
August 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28690972/computational-psychiatry-in-borderline-personality-disorder
#12
Sarah K Fineberg, Dylan Stahl, Philip Corlett
PURPOSE OF REVIEW: We review the literature on the use and potential use of computational psychiatry methods in Borderline Personality Disorder. RECENT FINDINGS: Computational approaches have been used in psychiatry to increase our understanding of the molecular, circuit, and behavioral basis of mental illness. This is of particular interest in BPD, where the collection of ecologically valid data, especially in interpersonal settings, is becoming more common and more often subject to quantification...
March 2017: Current Behavioral Neuroscience Reports
https://www.readbyqxmd.com/read/28678984/association-of-neural-and-emotional-impacts-of-reward-prediction-errors-with-major-depression
#13
Robb B Rutledge, Michael Moutoussis, Peter Smittenaar, Peter Zeidman, Tanja Taylor, Louise Hrynkiewicz, Jordan Lam, Nikolina Skandali, Jenifer Z Siegel, Olga T Ousdal, Gita Prabhu, Peter Dayan, Peter Fonagy, Raymond J Dolan
Importance: Major depressive disorder (MDD) is associated with deficits in representing reward prediction errors (RPEs), which are the difference between experienced and predicted reward. Reward prediction errors underlie learning of values in reinforcement learning models, are represented by phasic dopamine release, and are known to affect momentary mood. Objective: To combine functional neuroimaging, computational modeling, and smartphone-based large-scale data collection to test, in the absence of learning-related concerns, the hypothesis that depression attenuates the impact of RPEs...
August 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28678978/using-computational-psychiatry-to-rule-out-the-hidden-causes-of-depression
#14
Erdem Pulcu, Michael Browning
No abstract text is available yet for this article.
August 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28669207/computational-psychiatry-new-perspectives-on-mental-illnessedited-by-a-david-redish-ph-d-and-joshua-a-gordon-m-d-ph-d-cambridge-mass-mit-press-2016-424-pp-45-00-hardcover
#15
Tali M Ball, Andrea N Goldstein-Piekarski
No abstract text is available yet for this article.
July 1, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28641914/interactive-home-telehealth-and-burns-a-pilot-study
#16
Sean Hickey, Jason Gomez, Benjamin Meller, Jeffery C Schneider, Meredith Cheney, Shamim Nejad, John Schulz, Jeremy Goverman
OBJECTIVE: The objective of this study is to review our experience incorporating Interactive Home Telehealth (IHT) visits into follow-up burn care. METHODS: A retrospective review of all burn patients participating in IHT encounters over the course of 15 months was performed. Connections were established through secure video conferencing and call-routing software. Patients connected with a personal computer or tablet and providers connected with a desktop computer with a high-definition web camera...
June 19, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28640169/the-use-of-lorazepam-and-electroconvulsive-therapy-in-the-treatment-of-catatonia-treatment-characteristics-and-outcomes-in-60-patients
#17
Ahmet Unal, Abdurrahman Altindag, Bahadir Demir, Ihsan Aksoy
OBJECTIVES: Lorazepam and electroconvulsive therapy (ECT) are effective treatments for catatonia. However, systematic data on these treatments in catatonia are limited. In the present study, we aimed to investigate the clinical and treatment-related characteristics of patients with catatonia who underwent lorazepam and/or ECT. METHODS: Between January 2012 and December 2016, we received 60 patients with catatonia hospitalized in the Gaziantep University Faculty of Medicine Clinic of Psychiatry...
June 20, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28626229/linking-social-context-and-addiction-neuroscience-a-computational-psychiatry-approach
#18
Andrea Reiter, Andreas Heinz, Lorenz Deserno
No abstract text is available yet for this article.
June 19, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28619481/computational-psychosomatics-and-computational-psychiatry-toward-a-joint-framework-for-differential-diagnosis
#19
REVIEW
Frederike H Petzschner, Lilian A E Weber, Tim Gard, Klaas E Stephan
This article outlines how a core concept from theories of homeostasis and cybernetics, the inference-control loop, may be used to guide differential diagnosis in computational psychiatry and computational psychosomatics. In particular, we discuss 1) how conceptualizing perception and action as inference-control loops yields a joint computational perspective on brain-world and brain-body interactions and 2) how the concrete formulation of this loop as a hierarchical Bayesian model points to key computational quantities that inform a taxonomy of potential disease mechanisms...
May 25, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28618855/stability-of-and-factors-related-to-medical-student-specialty-choice-of-psychiatry
#20
Matthew N Goldenberg, D Keith Williams, John J Spollen
OBJECTIVE: Targeted efforts are needed to increase the number of medical students choosing psychiatry, but little is known about when students decide on their specialty or what factors influence their choice. The authors examined the timing and stability of student career choice of psychiatry compared with other specialties and determined what pre- and intra-medical school factors were associated with choosing a career in psychiatry. METHOD: Using survey data from students who graduated from U...
September 1, 2017: American Journal of Psychiatry
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