keyword
MENU ▼
Read by QxMD icon Read
search

Behcet's disease

keyword
https://www.readbyqxmd.com/read/29328521/the-central-vein-sign-differentiates-ms-from-cns-inflammatory-vasculopathies
#1
Pietro Maggi, Martina Absinta, Matteo Grammatico, Luisa Vuolo, Giacomo Emmi, Giovanna Carlucci, Gregorio Spagni, Alessandro Barilaro, Anna Maria Repice, Lorenzo Emmi, Domenico Prisco, Vittorio Martinelli, Roberta Scotti, Niloufar Sadeghi, Gaetano Perrotta, Pascal Sati, Bernard Dachy, Daniel S Reich, Massimo Filippi, Luca Massacesi
OBJECTIVES: In multiple sclerosis (MS), MRI is a sensitive tool for detecting white matter lesions, but its diagnostic specificity is still suboptimal; ambiguous cases are frequent in clinical practice. Detection of perivenular lesions in the brain (the "central vein sign") improves the pathological specificity of MS diagnosis, but comprehensive evaluation of this MRI biomarker in MS-mimicking inflammatory and/or autoimmune diseases, such as CNS inflammatory vasculopathies, is missing...
January 12, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29319272/behcet-s-disease-dilemma
#2
Ladli Chatterjee, A A Bamanikar
No abstract text is available yet for this article.
October 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29313056/generalized-purpura-as-an-atypical-skin-manifestation-of-adult-onset-still-s-disease-in-a-patient-with-beh%C3%A3-et-s-disease
#3
Chika Omigawa, Takashi Hashimoto, Takaaki Hanafusa, Takeshi Namiki, Ken Igawa, Hiroo Yokozeki
No abstract text is available yet for this article.
January 9, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29311362/novel-transcriptional-activity-and-extensive-allelic-imbalance-in-the-human-mhc-region
#4
Elizabeth Gensterblum-Miller, Weisheng Wu, Amr H Sawalha
The MHC region encodes HLA genes and is the most complex region in the human genome. The extensively polymorphic nature of the HLA hinders accurate localization and functional assessment of disease risk loci within this region. Using targeted capture sequencing and constructing individualized genomes for transcriptome alignment, we identified 908 novel transcripts within the human MHC region. These include 593 novel isoforms of known genes, 137 antisense strand RNAs, 119 novel long intergenic noncoding RNAs, and 5 transcripts of 3 novel putative protein-coding human endogenous retrovirus genes...
January 8, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29296024/beh%C3%A3-et-syndrome-a-contemporary-view
#5
REVIEW
Hasan Yazici, Emire Seyahi, Gulen Hatemi, Yusuf Yazici
The presence of symptom clusters, regional differences in disease expression and similarities with, for example, Crohn's disease suggest multiple pathological pathways are involved in Behçet syndrome. These features also make formulating disease criteria difficult. Genetic studies have identified HLA-B*51 to be the important genetic risk factor. However, the low prevalence of HLA-B*51 in many patients with bone fide disease, especially in non-endemic regions, suggests other factors must also be operative in Behçet syndrome...
January 3, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29287101/cancer-risk-in-korean-patients-with-beh%C3%A3-et-s-disease-a-nationwide-population-based-study
#6
Yoon Suk Jung, Minkyung Han, Do Young Kim, Jae Hee Cheon, Sohee Park
BACKGROUND: Various immune-mediated diseases are associated with increased malignancy risks. However, the relationship between Behçet's disease (BD) and cancer remains unclear. We conducted a nationwide, population-based study to determine the risk of cancer in patients with BD. METHODS: Using National Health Insurance claims records, we collected data from 2402 patients diagnosed with BD between 2013 and 2014. Standardized incidence ratios (SIRs) of overall and site-specific cancers in patients with BD in comparison with the general population were calculated...
2017: PloS One
https://www.readbyqxmd.com/read/29285231/associations-between-tnfsf4-tnfsf8-and-tnfsf15-and-beh%C3%A3-et-s-disease-but-not-vkh-syndrome-in-han-chinese
#7
Yan Jiang, Ling Cheng, Xin Li, Wenke Zhou, Li Zhang
The present study was designed to explore the interrelationship between single nucleotide polymorphisms (SNP) of the tumor necrosis factor superfamily (TNFSF) and its respective receptor superfamily (TNFRSF) genes and Behcet's disease (BD) and Vogt-Koyanagi-Harada syndrome (VKH) in Han Chinese. The study sample included 796 patients with BD, 792 patients with VKH syndrome, and 1604 healthy controls. The genotyping of 35 SNPs was performed by MassARRAY platform (Sequenom), iPLEX Gold Assay, PCR-restriction fragment length polymorphism assay and TaqMan SNP assay...
December 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/29260026/brain-biopsy-to-aid-diagnosis-of-neuro-beh%C3%A3-et-s-disease-case-report-and-literature-review
#8
Hiroki Yamada, Kazuyuki Saito, Mitsuhiko Hokari, Shuta Toru
Central nervous system involvement in Behçet's disease (Neuro-Behçet's disease: NBD) has been reported to present diverse clinical and pathological manifestations. A few cases presenting with neurological symptoms preceding other systemic features are difficult to be diagnosed. Here we suggest the clinical benefit of brain biopsy with a case of NBD initially presenting neurological symptoms.
September 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/29245353/multiple-aneurysms-and-gastrointestinal-involvement-in-behcet-s-disease-a-case-report
#9
Mengdi Wang, Weiwei Sun, Zhenjie Chen, Xiaona Wang, Jie Lv, Quanming Tan, Yaoxian Wang, Jingwei Zhou
RATIONALE: Behcet's disease (BD) is a rare systemic vasculitis disorder that can involve vessels of any size. PATIENT CONCERNS: A 60-year-old female had recurrent painful mouth ulcers about 30 years ago and recently presented with abdominal distension, conjunctival congestion, and chest pain in sequence. DIAGNOSES: The patient was diagnosed with BD according to the International Criteria for Behcet's Disease (ICBD). INTERVENTIONS: A therapy of glucocorticoids and cyclophosphamide was administered...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29245339/ten-year-progress-of-coronary-artery-lesions-prior-to-beh%C3%A3-et-disease-diagnosis-a-case-report-and-care-compliant-article
#10
Wenfang Ma, Yan Liang, Jun Zhu
INTRODUCTION: Behçet disease is a multisystemic chronic inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. However, particularly part of patients would present cardiovascular involvements and vascular lesions could be the presenting sign of Behçet disease preceding classical symptoms. We presented a middle aged male patient, in whom abdominal aorta pseudoaneurysm was as the first leading sign to reveal Behçet disease, and with his coronary artery lesions progress through a 10-year period before Behçet disease was diagnosed...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29241760/miscellaneous-skin-disease-and-the-metabolic-syndrome
#11
Sila Seremet, Mehmet Salih Gurel
The link between the metabolic syndrome (MetS) and skin diseases is increasingly important, with new associations being discovered. The association between MetS and psoriasis or MetS and hidradenitis suppurativa is well known, although the relationship between MetS and various autoimmune or inflammatory diseases has only recently attracted interest. Some inflammatory skin diseases, such as vitiligo, scleredema, recurrent aphthous stomatitis, Behçet disease, rosacea, necrobiosis lipoidica, granuloma annulare, skin tags, knuckle pads, and eruptive xanthomas, have possible associations with MetS...
January 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29225266/a-case-of-aortic-regurgitation-presenting-with-recurrent-detachment-of-a-prosthetic-valve-as-the-first-presenting-symptom-of-cardiovascular-beh%C3%A3-et-s-disease
#12
Tsugumi Takayama, Takuya Ozawa, Akiko Sanada, Tohru Watanabe, Masahiro Ito, Satoru Hirono, Yoshifusa Aizawa, Tohru Minamino
A 33-year-old man with severe aortic regurgitation underwent initial aortic valve replacement (AVR). During the 2 years after AVR, 3 reoperations for prosthetic valve detachment were required. During hospitalization, he had no typical clinical findings, with the exception of a persistent inflammatory reaction; a pseudo-aneurysm around the Bentall graft developed 27 days after the 4th operation. This unique clinical course suggested the possibility of Behçet's disease. In the 8 years of follow-up after the administration of prednisolone, the pseudo-aneurysm did not become enlarged and the detachment of the prosthetic valve was not observed...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29224587/the-prevalence-of-beh%C3%A3-et-s-disease-in-the-north-of-jordan-a-hospital-based-epidemiological-survey
#13
Wafa Y Madanat, Khaldoon M Alawneh, Mahmoud M Smadi, Salwa S Saadeh, Muntasser M Omari, Anas B Bani Hani, Hasan Yazici
OBJECTIVES: To estimate the prevalence of Behçet's disease (BD) in Jordan, with the additional aim of comparing this prevalence among hospital workers in other geographical areas. METHODS: In the first stage of our survey, 2,569 employees from 6 hospitals in north Jordan were interviewed using a screening questionnaire to identify individuals with recurrent oral ulcers (ROU), a previous diagnosis of BD (PDBD) and/or any major symptom related to BD. In the second stage, all individuals with ROU or PDBD identified at stage 1, were examined by 2 rheumatologists for the presence/confirmation of BD according to the International Study Group (ISG) criteria...
November 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29218258/breaking-the-magic-mouth-and-genital-ulcers-with-inflamed-cartilage-syndrome
#14
REVIEW
Stella Pak, Shaina Logemann, Christine Dee, Adam Fershko
Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome refers to a condition in which features of Behcet's disease (BD) and relapsing polychondritis (RP) occur in the same individual. The existence of MAGIC syndrome suggests a potential common etiology for BD and RP. However, connecting these two diseases and referring to this condition as MAGIC syndrome might have been premature, as there is currently insufficient knowledge on BD and RP. In this critical review, we argue that these two clinical entities could possibly be unique disease processes rather than two ends of the same disease spectrum...
October 4, 2017: Curēus
https://www.readbyqxmd.com/read/29208519/cardiac-involvement-in-a-patient-with-beh%C3%A3-et-disease-diagnostic-and-therapeutic-approach
#15
Ana Román Rego, José María García Acuña, Leyre Álvarez Rodríguez, Pedro Rigueiro Veloso, Diego López Otero, José Ramón González Juanatey
No abstract text is available yet for this article.
December 2, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29207867/updated-treatment-strategies-for-intestinal-beh%C3%A3-et-s-disease
#16
Yong Eun Park, Jae Hee Cheon
Behçet's disease (BD) is a chronic, idiopathic, relapsing immune-mediated disease involving multiple organs, and is characterized by recurrent oral and genital ulcers, ocular disease, gastrointestinal ulcers, vascular diseases, and skin lesions. In particular, gastrointestinal involvement in BD is followed by severe complications, including massive bleeding, bowel perforation, and fistula, which can lead to significant morbidity and mortality. However, the management of intestinal BD has not yet been properly established...
December 8, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29204391/mean-platelet-volume-a-reliable-marker-of-inflammation-in-recurrent-apthous-stomatitis-and-beh%C3%A3-et-disease
#17
Engin Şenel, Bilal Acar, Emre Demir
Background: Mean platelet volume (MPV) is an indicator of platelet activation and aggregation. MPV has been found to be related with the inflammation of certain disorders in recent studies. Aims: We sought to investigate whether MPV could be an indicator of inflammation in patients with Behçet disease (BD) and recurrent apthous stomatitis (RAS). Materials and Methods: Our study was designed as a retrospective case-control study and data was retrieved from our institutional database...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29202564/systematic-review-the-efficacy-of-topical-hyaluronic-acid-on-oral-ulcers
#18
M Casale, A Moffa, P Vella, V Rinaldi, M A Lopez, V Grimaldi, F Salvinelli
The management of oral ulcers is a challenge for clinicians. Whilst there is widespread use of topical corticosteroids, antibiotics and antimicrobial, there is only weak evidence for the effectiveness of any of the topical treatments. Hyaluronic Acid (HA) has been recently proposed for topical administration in the treatment of oral ulcers and other painful oral lesions. The aim of the study is to systematically review the published literature regarding all the therapeutic effects of HA on painful oral lesions such as oral ulcers and oral lichen planus...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29201328/hughes-stovin-syndrome-revealing-the-presence-of-beh%C3%A3-et-s-disease
#19
Melek Kechida, Sondes Yaacoubi, Ahmed Zrig, Walid Jomaa, Rim Klii, Sonia Hammami, Ines Khochtali
Background: Hughes-Stovin Syndrome (HSS) is a rare clinical disorder characterized by deep venous thrombosis and multiple pulmonary and/or bronchial aneurysms. Aneurysms in systemic circulation can also be seen. Case presentation: We report the first case of HSS with aortic aneurysm in a 55-year-old man who initially presented with deep venous thrombosis. The diagnosis of HSS revealing Behçet's disease was made given the history of recurrent oral and genital ulcers...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29196115/imaging-manifestations-of-behcet-s-disease-key-considerations-and-major-features
#20
REVIEW
Ghazaleh Mehdipoor, Fereydoun Davatchi, Hadi Ghoreishian, Abbas Arjmand Shabestari
Behcet's disease is an autoimmune disease most commonly seen in the Middle East. Although primarily known with painful oral and genital ulcers, it can lead to vasculitis. Therefore, several associated complications such as thrombotic syndromes, aneurysmal arterial disease may arise. In many cases, it might be difficult to make the diagnosis purely based on clinical grounds; however, imaging plays an important role for both diagnosis and assessment of the disease's complications. We provide a comprehensive review of the most notable imaging findings of Behcet's disease...
November 21, 2017: European Journal of Radiology
keyword
keyword
69678
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"