Giovanni Sighinolfi, Micaela Mitolo, Fabrizio Pizzagalli, Michelangelo Stanzani-Maserati, Daniel Remondini, Magali Jane Rochat, Elena Cantoni, Greta Venturi, Gianfranco Vornetti, Fiorina Bartiromo, Sabina Capellari, Rocco Liguori, Caterina Tonon, Claudia Testa, Raffaele Lodi
BACKGROUND: Being able to differentiate mild cognitive impairment (MCI) patients who would eventually convert (MCIc) to Alzheimer's disease (AD) from those who would not (MCInc) is a key challenge for prognosis. OBJECTIVE: This study aimed to investigate the ability of sulcal morphometry to predict MCI progression to AD, dedicating special attention to an accurate identification of sulci. METHODS: Twenty-five AD patients, thirty-seven MCI and twenty-five healthy controls (HC) underwent a brain-MR protocol (1...
April 17, 2024: Journal of Alzheimer's Disease: JAD