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Platelet lymphocyte ratio

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https://www.readbyqxmd.com/read/29326773/clinical-outcomes-of-patients-undergoing-rotational-atherectomy-followed-by-drug-eluting-stent-implantation-a-single-center-real-world-experience
#1
Lucky R Cuenza, Ada Cherryl Jayme, James Ho Khe Sui
Background: Rotational atherectomy (RA) is used to improve procedural success of percutaneous catheter interventions (PCIs) of complex and heavily calcified coronary lesions. We report the clinical experience and outcomes in our institution with the use of RA, followed by drug-eluting stent implantation. Materials and Methods: Data of 81 patients treated with PCI and adjunctive RA were analyzed. Clinical follow-up for the occurrence of major adverse events (MAEs) was obtained in all patients and correlated with significant variables using multivariate Cox proportional hazards analysis...
October 2017: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/29325800/platelet-to-lymphocyte-ratio-is-a-predictive-marker-of-prognosis-and-therapeutic-effect-of-postoperative-chemotherapy-in-non-metastatic-esophageal-squamous-cell-carcinoma
#2
Yuchong Yang, Hao Xu, Likun Zhou, Ting Deng, Tao Ning, Rui Liu, Le Zhang, Xia Wang, Shaohua Ge, Hongli Li, Yi Ba
Increasing evidence indicated that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and prognostic nutritional index (PNI), can be used as prognostic indicators in esophageal squamous cell carcinoma (ESCC). However, which is the best predictor for prognosis in ESCC remain controversial. Few studies focused on the association between inflammatory biomarkers and postoperative chemotherapy. A cohort of 515 non-metastatic ESCC patients was reviewed retrospectively...
January 8, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29325504/platelet-to-lymphocyte-ratio-neutrophil-to-lymphocyte-ratio-and-platelet-indices-in-patients-with-acute-deep-vein-thrombosis
#3
Liang Ming, Zhiyun Jiang, Junfen Ma, Qian Wang, Fan Wu, Jiedan Ping
BACKGROUND: Inflammation is associated with an increased risk of thrombotic events and complete blood count (CBC) is an easily measured test. The purpose of this study was to evaluate the value of CBC relative parameters including mean platelet volume (MPV), platelet-to-lymphocyte ratio (PLR), mean platelet volume-to-lymphocyte ratio (MPVLR), and neutrophil-to-lymphocyte ratio (NLR) for patients with acute deep vein thrombosis (DVT). PATIENTS AND METHODS: A total of 115 patients with unprovoked DVT of the lower extremities and 105 controls were recruited in this study...
January 12, 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29325323/-platelet-to-lymphocyte-ratio-in-peripheral-blood-and-body-mass-index-novel-independent-prognostic-factors-in-patients-with-melanoma
#4
Y L Qi, Y Zhang, L D Zhao, A X Wang, Z B Wang, Q L Gao
Objective: To investigate whether platelet to lymphocyte ratio (PLR) in peripheral blood and body mass index (BMI) can be independent prognostic factors in patients with melanoma. Methods: Clinical date of 140 patients with melanoma in the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital from January 1, 2010 to December 31, 2015 were analyzed retrospectively.Receiver operating characteristic (ROC) curve was performed the optimal cut-off value for PLR.The 140 patients were divided into high PLR group and low PLR group...
December 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29299368/evaluation-of-the-prognostic-value-of-platelet-to-lymphocyte-ratio-in-patients-with-hepatocellular-carcinoma
#5
Yuchen Wang, Bashar M Attar, Harry E Fuentes, Palashkumar Jaiswal, Alfonso J Tafur
Background: Hepatocellular carcinoma (HCC) is increasingly common, potentially fatal cancer type globally. Platelet-lymphocyte ratio (PLR) as a biomarker for systemic inflammation has recently been recognized as a valuable prognostic marker in multiple cancer types. The aim of the present study was to assess the prognostic value of PLR in HCC patients and determine the optimal cut-off value for risk stratification. Methods: We retrospectively analyzed patients with diagnosis of HCC (screened by ICD-9 code, confirmed with radiographic examination and/or biopsy) at a large public hospital during 15 years (Jan 2000 through July 2015)...
December 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29299149/the-combination-of-preoperative-platelet-count-and-neutrophil-lymphocyte-ratio-as-a-prognostic-indicator-in-localized-renal-cell-carcinoma
#6
Takuya Tsujino, Kazumasa Komura, Atsushi Ichihashi, Takeshi Tsutsumi, Tomohisa Matsunaga, Yuki Yoshikawa, Ryoichi Maenosono, Kyohei Okita, Tomoaki Takai, Rintaro Oide, Koichiro Minami, Hirofumi Uehara, Kohei Taniguchi, Hajime Hirano, Hayahito Nomi, Naokazu Ibuki, Kiyoshi Takahara, Teruo Inamoto, Haruhito Azuma
Introduction: The combination of platelet count and neutrophil to lymphocyte ratio (COP-NLR) has been shown to provide prognostic information in several cancers, whereas its prognostic value in renal cell carcinoma (RCC) has not been reported. The objective of the present study was to examine the preoperative prognostic value of the COP-NLR in patients with localized RCC undergoing nephrectomy. Material and Methods: The record of 268 patients, who underwent nephrectomy due to a diagnosis of RCC at our institute was analyzed in the study...
December 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/29290784/systemic-inflammation-biomarkers-predict-survival-in-patients-of-early-stage-non-small-cell-lung-cancer-treated-with-stereotactic-ablative-radiotherapy-a-single-center-experience
#7
Hui Luo, Hong Ge, Yingying Cui, Jiangong Zhang, Ruitai Fan, Anping Zheng, Xiaoli Zheng, Yanan Sun
Background: Increasing evidence indicates a relationship between systemic inflammation and survival following treatment in various tumors. However, the correlation of systematic inflammation with survival after stereotactic ablative radiotherapy (SABR) in early stage non-small cell lung cancer (NSCLC) has not been well established. Patients and methods: We retrospectively analyzed patients with newly diagnosed early stage NSCLC treated with SABR in a single institution from 2011 to 2015. The neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and lymphocyte- monocyte ratio (LMR) were calculated as systemic inflammation biomarkers...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29285194/combination-of-the-neutrophil-to-lymphocyte-ratio-and-the-platelet-to-lymphocyte-ratio-as-a-useful-predictor-for-recurrence-following-radiofrequency-ablation-of-hepatocellular-carcinoma
#8
Kai Chen, Mei-Xiao Zhan, Bao-Shan Hu, Yong Li, Xu He, Si-Rui Fu, Yong-Jie Xin, Li-Gong Lu
The aim of the present study was to investigate the prognostic potential of a novel inflammation-based system, the combination of the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) (CNP), for predicting the survival time of patients with hepatocellular carcinoma (HCC) who had received radiofrequency ablation (RFA). A total of 287 HCC patients treated with RFA were enrolled in the study. Patients with an elevated NLR (>2.58) and an elevated PLR (>131.78) were allocated a score of 2, and patients exhibiting one or neither of these characteristics were allocated a score of 1 or 0, respectively...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29275426/platelet-to-lymphocyte-ratio-predicts-long-term-survival-in-laryngeal-cancer
#9
Yize Mao, Yan Fu, Yunfei Gao, Ankui Yang, Quan Zhang
OBJECTIVES: Although the survival rate of laryngeal cancer is relatively high, some patients with laryngeal squamous cell carcinoma (LSCC) show the least benefit from laryngectomy, owing to few determining diagnostic tools. We aimed to identify high-risk patients according to a preoperatively determined signature of the platelet-to-lymphocyte ratio (PLR) of > 193.55, as an indicator of poor treatment outcome in LSCC patients. METHODS: We retrospectively evaluated 899 patients who underwent laryngectomy for LSCC...
December 23, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29260361/sex-dependent-association-of-preoperative-hematologic-markers-with-glioma-grade-and-progression
#10
Wenshen Xu, Dengliang Wang, Xiaobin Zheng, Qishui Ou, Liming Huang
Neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio, the systemic immune-inflammation index (SII), and red blood cell distribution width (RDW), have been recognized as promising predictors for histological grade and prognosis in multiple cancer types. However, few investigations illustrated the impacts of sex on the clinical utility of hematologic markers. Patients with primary gliomas were retrospectively reviewed. The association between grade and inflammatory markers by sex were investigated by univariate and multivariate analysis...
December 19, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29259209/hemographic-indices-are-associated-with-mortality-in-acute-heart-failure
#11
Wei-Ming Huang, Hao-Min Cheng, Chi-Jung Huang, Chao-Yu Guo, Dai-Yin Lu, Ching-Wei Lee, Pai-Feng Hsu, Wen-Chung Yu, Chen-Huan Chen, Shih-Hsien Sung
Hemographic indices have been associated with clinical outcomes in patients with chronic heart failure. We therefore investigated the prognostic values of hemographic indices in patients hospitalized for acute heart failure (AHF). Patients hospitalized primarily for AHF were drawn from an intramural registry. Hemographic indices, including white blood cell counts, neutrophil counts, neutrophil-to-lymphocyte ratio, reciprocal of lymphocyte (RL) and platelet-to-lymphocyte ratio were recorded. Among a total of 1923 participants (mean age 76 ± 12 years, 68% men), 875 patients died during a mean follow-up of 28...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29251364/after-neoadjuvant-chemotherapy-platelet-lymphocyte-ratios-negatively-correlate-with-prognosis-in-gastric-cancer-patients
#12
Weipeng Gong, Lei Zhao, Zhaogang Dong, Yu Dou, Yanguo Liu, Chao Ma, Xun Qu
INTRODUCTION: Circulating predictors prognostic factors of neoadjuvant chemotherapy, which identify the patients who are potential possibly to benefit from it are limited at present. In this research, we aimed to compare the prognostic significance of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in patients with locally advance gastric carcinoma who were treated with neoadjuvant chemotherapy (NAC) followed by D2 gastrectomy. MATERIALS AND METHODS: From 2007 to 2015, 91 patients with locally advanced gastric cancer treated with NAC followed by D2 gastrectomy included in this retrospective cohort study...
December 18, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29243847/utility-of-complete-blood-count-parameters-to-detect-premature-ovarian-insufficiency-in-cases-with-oligomenorrhea-amenorrhea
#13
Ilhan Sanverdi, Cetin Kilicci, Ebru Cogendez, Cigdem Abide Yayla, Enis Ozkaya
BACKGROUND: There are very few biomarkers available to diagnose cases with premature ovarian failure. Some complete blood count parameters have been introduced to be diagnostic biomarkers for several disorders associated with inflammatory process. Due to the evidence that indicated chronic inflammatory process to be underlying pathophysiology in premature ovarian insufficiency (POI), we aimed to assess the predictive value of complete blood count parameters for POI diagnosis. METHOD: A total of 96 women diagnosed to have premature ovarian failure were compared with 110 otherwise healthy women in terms of some basal hormone levels and complete blood count parameters...
December 15, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29241668/neutrophil-to-lymphocyte-ratio-is-a-strong-predictor-of-atherosclerotic-carotid-plaques-in-older-adults
#14
T Corriere, S Di Marca, E Cataudella, A Pulvirenti, S Alaimo, B Stancanelli, L Malatino
BACKGROUND AND AIMS: The Neutrophil-to-Lymphocyte Ratio (NLR), an index of systemic inflammation, has been reported to be associated with subclinical atherosclerosis, but its predictive role of the presence of carotid atherosclerotic plaques remains undefined. This study aims to assess this association which gives additional value to this biomarker, with respect to the main risk factors, in the prediction of carotid atherosclerosis in older adults. METHODS AND RESULTS: We recruited 324 patients, aged ≥65 years, without hematopoietic disorders, and/or history of malignancies, evidence of acute infections, chronic inflammatory status, and history of glucocorticoid therapy within the past three months, hospitalized in the Unit of Internal Medicine, University of Catania, Catania, Italy from January 2014 to December 2016...
November 5, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29240565/platelets-to-lymphocyte-ratio-is-a-good-predictor-of-liver-fibrosis-and-insulin-resistance-in-hepatitis-c-virus-related-liver-disease
#15
Ayman Alsebaey, Mostafa Elhelbawy, Imam Waked
BACKGROUND: Hepatitis C virus (HCV) is a global health problem that is complicated by liver fibrosis and insulin resistance (IR). AIM: The aim of this study was to validate neutrophils-to-lymphocytes ratio (NLR) and platelets-to-lymphocytes ratio (PLR) as indirect biomarkers of liver fibrosis and IR in HCV patients. PATIENTS AND METHODS: One hundred and fifty patients were enrolled. Physical examination, BMI, liver function tests, serum creatinine, complete blood count, serum HCV RNA count by PCR, and abdominal ultrasonography were performed...
February 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29236646/evaluation-of-bone-mineral-density-bmd-and-indicators-of-bone-turnover-in-patients-with-hemophilia
#16
Mehmet Dagli, Ali Kutlucan, Sedat Abusoglu, Abdulkadir Basturk, Mehmet Sozen, Leyla Kutlucan, Ali Unlu, Farise Yilmaz
A decrease in bone mass is observed in hemophilic patients. The aim of this study was to evaluate bone mineral density (BMD), parathyroid hormone (PTH), 25-hydroxy vitamin D (vitamin D), and a bone formation and resorption marker, procollagen type I N-terminal propeptide (PINP) and urinary N-terminal telopeptide (uNTX) respectively, in hemophilic patients and healthy controls. Laboratory parameters related to the pathogenesis of bone loss such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) were also evaluated...
December 13, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29236347/the-full-blood-count-as-an-ancillary-test-to-support-the-diagnosis-of-giant-cell-arteritis
#17
Lawrence J Oh, Eugene Wong, Juliana Andrici, Peter McCluskey, James E H Smith, Anthony J Gill
BACKGROUND: Temporal artery biopsy is considered the investigation of choice to definitively diagnose giant cell arteritis in patients with compatible symptoms. However it is invasive and not completely sensitive. Serum markers, particularly ESR, can be supportive but are not definitive in individual cases. AIMS: We sought to investigate whether indices derived from the full blood count including neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), were associated with a positive biopsy in patients with suspected giant cell arteritis...
December 13, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29235538/preoperative-neutrophil-to-lymphocyte-ratio-and-tumor-related-factors-to-predict-lymph-node-metastasis-in-nonfunctioning-pancreatic-neuroendocrine-tumors
#18
Bo Zhou, Junfang Deng, Lifeng Chen, Shusen Zheng
The lymph node (LN) status is very important for the survival in pancreatic neuroendocrine tumors (PNETs). Therefore, the investigation of factors related to LN metastases has a great clinical significance. The aim of this study was to evaluate the predictive value of the preoperative neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and possible clinical parameters on the LN metastases in nonfunctional PNETs (NF-PNETs). A retrospective review of 101 NF-PNET patients following curative resection and lymphadenectomy was conducted...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29228745/prognostic-role-of-the-pre-treatment-platelet-lymphocyte-ratio-in-pancreatic-cancer-a-meta-analysis
#19
Zheng-Shui Xu, Fa-Peng Zhang, Yin Zhang, Yong-Peng Ou-Yang, Xiao-Wen Yu, Wen-Long Wang, Wen-Ji Xu, Zhi-Qiang Luo
Background and Aims: Recently, the pre-treatment platelet-lymphocyte ratio (PLR), which is based on blood parameters, was accepted as a prognostic factor for patients with various cancers. Numerous studies have investigated the prognostic role of the PLR in pancreatic cancer; however, it remains unclear. Therefore, we conducted this meta-analysis to evaluate the relationship between the pre-treatment PLR and overall survival (OS) in pancreatic cancer. Materials and Methods: We performed a systematic literature search of the PubMed, Embase and Web of Science databases for relevant studies that explored the prognostic role of the pre-treatment PLR in pancreatic cancer...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29228679/prognostic-value-of-the-c-reactive-protein-albumin-ratio-car-in-patients-with-operable-soft-tissue-sarcoma
#20
Yao Liang, Wei Xiao, Yuan-Xiang Guan, Wei Wang, Huo Ying Chen, Cheng Fang, Xing Zhang, Zhi-Wei Zhou
Background: The preoperative C-reactive protein/Albumin ratio (CAR) is valuable for predicting the prognosis of patients with various types of cancers. The aim of the present study is to investigate the prognostic value of the preoperative CAR and compare it with other systemic inflammatory response markers in patients with soft tissue sarcoma (STS). Methods: This retrospective study included 206 patients with STS. The optimal cutoff value of the CAR was determined by receiver operating characteristic (ROC) analysis...
November 17, 2017: Oncotarget
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