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Platelet lymphocyte ratio

Ke Jiang, Jianyong Lei, Wenjie Chen, Yanping Gong, Han Luo, Zhihui Li, Rixiang Gong, Jingqiang Zhu
The preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are known to be prognostic factors in several cancers. However, no previous investigation has been performed to evaluate the significance of the NLR and PLR in medullary thyroid carcinoma (MTC).The aim of this study was to identify the ability of the preoperative NLR or PLR to predict lymph node metastasis and recurrence in patients with MTC. Data from all patients with MTC who had undergone surgery at our institution from May 2009 to May 2016 were retrospectively evaluated...
October 2016: Medicine (Baltimore)
Marialaura Bonaccio, Augusto Di Castelnuovo, George Pounis, Amalia De Curtis, Simona Costanzo, Mariarosaria Persichillo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Low-grade inflammation is associated with increased risk of chronic degenerative disease but its relationship with mortality is less explored. We aimed at evaluating, at a large epidemiological level, the possible association of low-grade inflammation, as measured by a composite score, with overall mortality risk. We conducted a population-based prospective investigation on 20,337 adult subjects free from major haematological disease and acute inflammatory status, randomly recruited from the general population of the Moli-sani study...
October 14, 2016: Haematologica
Wencong Ma, Ping Zhang, Jun Qi, Litong Gu, Mingcui Zang, Haochen Yao, Xiaoju Shi, Chunli Wang, Ying Jiang
This study was designed to evaluate the prognostic value of platelet to lymphocyte ratio (PLR) in hepatocellular carcinoma (HCC). A comprehensive literature search for relevant studies was performed in Web of science, Embase and Pubmed. A total of nine studies with 2017 patients were included in this meta-analysis, and combined hazard ratio (HR) or odds ratio (OR) and 95% confidence intervals (95%CIs) were served as effect measures. Pooled results showed that elevated PLR was associated with poor overall survival (OS) (HR = 1...
October 14, 2016: Scientific Reports
Cigdem Abide Yayla, Enis Ozkaya, Ahter Tayyar, Taylan Senol, M Baki Senturk, Ates Karateke
BACKGROUND: The aim of this study was to assess the relationship between some complete blood count parameters and placental invasion anomalies. METHODS: Totally 146 pregnants who were suspected for placental invasion anomalies underwent complete blood count screening before cesarean section. In all subjects white blood cell, lymphocyte, neutrophil and platelet counts with red cell distribution width, mean platelet volume, hemoglobin and hematocrit levels were analysed...
October 13, 2016: Journal of Maternal-fetal & Neonatal Medicine
Orietta Dalpiaz, Daniel Krieger, Georg C Ehrlich, Kristof Pohlmann, Tatjana Stojakovic, Karl Pummer, Richard Zigeuner, Martin Pichler, Georg C Hutterer
INTRODUCTION: This study is aimed at investigating the potential prognostic impact of the preoperatively assessed platelet-to-lymphocyte ratio (PLR) in a European cohort of patients with non-metastatic upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS: Clinicopathological data from 180 consecutive non-metastatic UTUC patients, operated between 1990 and 2012 at a single tertiary academic center, were evaluated retrospectively. The preoperative PLR was assessed one day before surgery...
October 13, 2016: Urologia Internationalis
Hong-Bo Yang, Meng Xing, Lei-Na Ma, Ling-Xin Feng, Zhuang Yu
SETTING: For now, hematological markers of inflammatory response have emerged as prognostic factors for patients with cancer. Many articles have confirm that neutrophil to lymphocyte ratio(NLR) and platelet-lymphocyte ratio (PLR) are relate with poor prognosis in various types of tumors Objective: To investigate the association between NLR/PLR and progression free survival (PFS), overall survival (OS) and clinicopathologic parameters in lung cancer patients. DESIGN: We performed relevant searches in PubMed database, Google Scholar, Springer Link...
October 8, 2016: Oncotarget
Goutham Reddy K, M Jagadesh, K Ranjan Shetty
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Ahmet Goktug Ertem, Cagri Yayla, Burak Acar, Ozgur Kırbas, Sefa Unal, Melahat Uzel Sener, Mehmet Kadri Akboga, Tolga Han Efe, Serkan Sıvrı, Fatih Sen, Serkan Gokaslan, Serkan Topaloglu
INTRODUCTION: The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio etc.) Objectives: We investigated the predictive value of lymphocye to monocyte ratio (LMR) for mortality in first 30 days after APE. METHODS: The study population included 294 APE patients of which 230 patients survivors, 64 patients non-survivors. RESULTS: Lymphocye to monocyte ratio was significantly lower in non-survivors after APE (p<0...
October 11, 2016: Clinical Respiratory Journal
Jong-Han Lee, Sungwook Song, Soo-Young Yoon, Chae Seung Lim, Jae-Woo Song, Hyon-Suk Kim
No abstract text is available yet for this article.
July 2016: British Journal of Biomedical Science
Cheryl Sarah Philipose, T Umashankar
INTRODUCTION: Malaria is a mosquito borne disease which is a major public health problem and a leading cause of morbidity and mortality worldwide. Various haematological parameters have been studied to help predict malaria, such as alteration in the leucocyte count, platelet counts and erythrocyte counts. The neutrophil lymphocyte count ratio (NLCR) was found to have a good predictive value in systemic inflammation, particularly in critical care setting. AIMS AND OBJECTIVES: The present study aims to study the various haematological parameters and acertain the predictive value of NLCR and MLR in the detection of malaria...
July 2016: Tropical Parasitology
Mehmet Artaç, Mükremin Uysal, Mustafa Karaağaç, Levent Korkmaz, Zehra Er, Tunç Güler, Melih Cem Börüban, Hakan Bozcuk
PURPOSE: Metastatic colorectal cancer (mCRC) is a lethal disease and fluorouracil-leucovorin-irinotecan (FOLFIRI) plus bevacizumab (bev) is a standard approach. Hence, there is a strong need for identifying new prognostic factors to show the efficacy of FOLFIRI-bev. METHODS: This is a retrospective study including patients (n = 90) with mCRC from two centers in Turkey. Neutrophil/lymphocyte (N/L) ratio, platelet count, albumin, and C-reactive protein (CRP) were recorded before FOLFIRI-bev therapy...
October 7, 2016: Journal of Gastrointestinal Cancer
Kevser Gülcihan Balci, Mustafa Mücahit Balci, Ugur Arslan, Burak Açar, Orhan Maden, Hatice Selcuk, Timur Selcuk
BACKGROUND: Platelet-to-lymphocyte ratio (PLR) and relative lymphocyte count (L%) are commonly available tests that can be obtained from complete blood count. The aim of this study was to investigate the association between appropriate defibrillator therapy and PLR, and whether decreased lymphocyte count may predict appropriate implantable cardioverter defibrillator (ICD) shocks in heart failure (HF) patients. METHODS: A total of 147 patients with ischemic or non-ischemic HF who underwent ICD implantation for primary prevention were enrolled in this study...
September 2016: Acta Cardiol Sin
I-Chih Chen, Chao-Chin Yu, Yi-Hsuan Wu, Ting-Hsing Chao
BACKGROUND: Inflammation plays an important role in the pathogenesis of cardiovascular disease in patients with advanced chronic kidney disease (CKD). Neutrophil-to-lymphocyte ratio (NLR), an inflammatory biomarker, has not been evaluated in patients who have advanced CKD with peripheral artery disease (PAD) undergoing percutaneous transluminal angioplasty (PTA), especially in Taiwan. METHODS: We retrospectively evaluated 148 advanced CKD (creatinine clearance rate ≤ 30 mL/min/1...
September 2016: Acta Cardiol Sin
Pietro Salvago, Serena Rizzo, Antonino Bianco, Francesco Martines
OBJECTIVE: To investigate the relationship between haematological routine parameters and audiogram shapes in patients affected by sudden sensorineural hearing loss (SSNHL). DESIGN: A retrospective study. All patients were divided into four groups according to the audiometric curve and mean values of haematological parameters (haemoglobin, white blood cell, neutrophils and lymphocytes relative count, platelet count, haematocrit, prothrombin time, activated partial thromboplastin time, fibrinogen and neutrophil-to-lymphocite ratio) of each group were statistically compared...
October 7, 2016: International Journal of Audiology
Hale Ates, Ihsan Ates, Harun Kundi, Fatma Meric Yilmaz
BACKGROUND: The aim of this study was to determine the hematologic parameter with the highest diagnostic differentiation in the identification of massive acute pulmonary embolism (APE). METHODS: A retrospective study was performed on patients diagnosing with APE between June 2014 and June 2016. All radiological and laboratory parameters of patients were scanned through the electronic information management system of the hospital. PLR was obtained from the ratio of platelet count to lymphocyte count, NLR was obtained from the ratio of neutrophil count to lymphocyte count, WMR was obtained from white blood cell in mean platelet volume ratio, MPR was obtained from the ratio of mean platelet volume to platelet count, and RPR was obtained from the ratio of red distribution width to platelet count...
October 6, 2016: Journal of Clinical Laboratory Analysis
Hasan Huseyin Ozdemir
The purpose of this study was to investigate the prognostic value of the pretreatment and post-treatment albumin level, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in subtypes of Guillain-Barré syndrome (GBS). A retrospective analysis of 62 patients with GBS treated between 2011 and 2015 in Dicle University Hospital, Turkey, was carried out. The pretreatment and post-treatment albumin, NLR, and PLR were documented, together with acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy, motor sensory axonal neuropathy, and Hughes' scores...
September 2016: Arquivos de Neuro-psiquiatria
Xin Wang, Feifei Teng, Li Kong, Jinming Yu
BACKGROUND: The inflammatory response indexes, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), have prognostic value for a variety of cancers. However, their prognostic value for small-cell lung cancer (SCLC) has been rarely reported. In this study, we monitored changes of NLR and PLR along with the clinical outcomes in patients with limited-stage and extensive-stage SCLC who received standard treatments. MATERIALS AND METHODS: We retrospectively reviewed the records of 153 patients who were pathologically diagnosed with SCLC and collected their hematological data at different time points during disease and treatment process...
2016: OncoTargets and Therapy
Nan Ding, ZhaoFei Pang, Hongchang Shen, Yang Ni, Jiajun Du, Qi Liu
Recently, many studies have been conducted to explore prognostic value of platelet to lymphocyte ratio (PLR) for patients with lung cancer, while the results remain controversial. We collected pretreatment, clinicopathological and follow-up data of 1388 lung cancer patients receiving surgery between 2006 and 2011 in our hospital, and reviewed relevant articles from Embase, Pubmed, Web of science databases, then performed a meta-analysis to clarify the relationship between PLR and prognosis of lung cancer patients...
October 5, 2016: Scientific Reports
Hui-Bing Zhang, Juan Chen, Qiao-Fen Lan, Xiong-Jian Ma, Shi-Yan Zhang
The aim of this study was to evaluate the diagnostic efficiency of red blood cell distribution width (RDW), platelet distribution width (PDW), the neutrophil-lymphocyte count ratio (NLCR), procalcitonin (PCT) and C-reactive protein (CRP) for the prediction of sepsis. A total of 120 consecutive patients who underwent blood culture testing were included. The PCT and CRP levels, and RDW, PDW and NLCR percentages were determined and compared between patients with positive blood cultures and those without. The PCT, CRP, RDW, PDW and NLCR values were significantly higher in patients with positive blood culture compared with those without...
October 2016: Experimental and Therapeutic Medicine
Shih-Hua Fang, Katsuhiko Suzuki, Chin Leong Lim, Ming-Shun Chung, Po-Wen Ku, Li-Jung Chen
Sleep disorder is a risk factor for several systemic inflammation-related diseases and there are extensive data showing that schizophrenia is associated with chronic low-grade systemic inflammation. This study investigated the associations between sleep quality and inflammatory markers in patients with schizophrenia, which has not been examined before. Sleep quality (total sleep time, sleep efficiency, sleep onset latency, total activity counts, wake after sleep onset, number of awakening, and average length of awakening) was measured using actigraphy in 199 schizophrenia inpatients...
September 21, 2016: Psychiatry Research
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