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Platelet lymphocyte ratio

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https://www.readbyqxmd.com/read/28431566/the-prognostic-value-of-the-preoperative-c-reactive-protein-albumin-ratio-in-ovarian-cancer
#1
Yubo Liu, Shengfu Chen, Chengyu Zheng, Miao Ding, Lan Zhang, Liangan Wang, Meiqing Xie, Jianhua Zhou
BACKGROUND: Inflammation plays an important role in the pathogenesis of ovarian cancer. This study sought to investigate the association between the preoperative c-reactive protein/albumin ratio (CRP/Alb) and oncological outcomes in ovarian cancer patients. METHODS: Two hundred patients with histologically verified ovarian cancer between June 2006 and July 2012 were retrospectively reviewed. Overall survival was evaluated by the Kaplan-Meier method and log-rank test...
April 21, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28428718/clinical-implication-of-fdg-uptake-of-bone-marrow-on-pet-ct-in-gastric-cancer-patients-with-surgical-resection
#2
Jeong Won Lee, Moon-Soo Lee, Il Kwon Chung, Myoung Won Son, Young Sin Cho, Sang Mi Lee
AIM: To determine the relationship between F-18 fluorodeoxyglucose (FDG) uptake of bone marrow (BM) on positron emission tomography/computed tomography (PET/CT) and clinical factors and to assess the prognostic value of FDG uptake of BM in gastric carcinoma. METHODS: We retrospectively enrolled 309 gastric cancer patients who underwent staging FDG PET/CT and curative surgical resection. FDG uptake of primary tumor was visually classified as positive or negative FDG uptake...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28427174/association-of-immunologic-markers-from-complete-blood-counts-with-the-response-to-preoperative-chemoradiotherapy-and-prognosis-in-locally-advanced-rectal-cancer
#3
Sung Woo Jung, In Ja Park, Se Heon Oh, Seung-Seop Yeom, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Jung Bok Lee, Chang Sik Yu, Jin Cheon Kim
We investigated retrospectively whether immunologic markers from a complete blood count (CBC) are associated with the responsiveness to preoperative chemoradiotherapy (PCRT) and oncologic outcomes in 984 patients with locally advanced rectal cancer (LARC) who also underwent radical surgery from 2005 to 2013. CBC parameters including the neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and platelet to lymphocyte ratio (PLR) were recorded. Pathologic responses to PCRT were evaluated in the resected specimens using the tumor regression grade system...
February 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423351/significance-of-inflammation-based-indices-in-the-prognosis-of-patients-with-non-metastatic-colorectal-cancer
#4
Xiangping Song, Hong Zhu, Qian Pei, Fengbo Tan, Chenglong Li, Zhongyi Zhou, Yuan Zhou, Nanhui Yu, Yuqiang Li, Haiping Pei
Previous studies demonstrated that several inflammation-based hematological indices are closely related to various malignancies, including colorectal cancer (CRC). In this study, the prognostic value of inflammation-based markers, including a combination index termed coNLR-PDW, comprising the preoperative neutrophil-to-lymphocyte ratio (NLR) and the platelet distribution width (PDW), was evaluated in 206 patients with non-metastatic CRC treated with surgery at a single medical center. The association of patient demographics, blood chemistry, and serum biochemical indices with recurrence-free survival (RFS) and overall survival (OS) were examined through univariate and multivariate analysis...
April 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28418850/the-prognostic-value-of-preoperative-neutrophils-platelets-lymphocytes-monocytes-and-calculated-ratios-in-patients-with-laryngeal-squamous-cell-cancer
#5
Chiyao Hsueh, Lei Tao, Ming Zhang, Wenjun Cao, Hongli Gong, Jian Zhou, Liang Zhou
This study was aimed to examine the prognostic value of preoperative neutrophils, platelets, lymphocytes, monocytes and calculated ratios in patients with laryngeal squamous cell cancer (LSCC). From January 2007 to December 2011, 979 patients with LSCC were enrolled in our study. Preoperative neutrophils, platelets, lymphocytes, monocytes, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) were analyzed. Besides well-established clinicopathological prognostic factors, we evaluated the independent prognostic relevance of these hematological parameters by Cox regression models in disease-free survival (DFS) and cancer-specific survival (CSS)...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414280/neutrophil-to-lymphocyte-and-platelet-to-lymphocyte-ratios-in-pediatric-patients-with-idiopathic-sudden-hearing-loss
#6
Suphi Bulğurcu, Bünyamin Dikilitaş, İlker Burak Arslan, İbrahim Çukurova
OBJECTIVE: We investigated the significance of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios, which have recently been used in adults for the prognosis of idiopathic sudden hearing loss (ISHL), in the prognosis of idiopathic sudden hearing loss in a pediatric population. MATERIALS AND METHODS: A total of 13 males and 8 females younger than19 years with idiopathic sudden hearing loss were retrospectively examined between January 2008 and August 2016...
April 17, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28412759/preoperative-monocyte-lymphocyte-and-neutrophil-lymphocyte-but-not-platelet-lymphocyte-ratios-are-predictive-of-clinical-outcomes-in-resected-patients-with-non-metastatic-siewert-type-ii-iii-adenocarcinoma-of-esophagogastric-junction-a-prospective-cohort-study
#7
Jia-Wei Zhang, Lei Huang, A-Man Xu
AIMS: To propectively reveal the clinicopathological and prognostic significances of monocyte-lymphocyte ratio (MLR), neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in resected patients with non-metastatic Siewert type II/III adenocarcinoma of esophagogastric junction (AEG). METHODS: A total of 611 patients diagnosed with Siewert type II/III AEG and undergoing surgery between 2006 and 2011 were prospectively followed-up until April 2016. Associations between preoperative peripheral MLR, NLR, and PLR and clinicopathological parameters were quantified using the multivariate Logistic regression model with adjustment...
February 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28412137/are-markers-of-systemic-inflammation-good-prognostic-indicators-in-colorectal-cancer
#8
REVIEW
Sabrina Rossi, Michele Basso, Antonia Strippoli, Giovanni Schinzari, Ettore D'Argento, Mario Larocca, Alessandra Cassano, Carlo Barone
Systemic inflammation has been proved to play a crucial role in promoting cancer progression and metastasis in many cancer types, including colorectal cancer (CRC). The aim of the present review was to provide an overview of studies regarding the prognostic value of inflammation-based markers in patients with CRC. A literature search was performed for articles reporting the prognostic value of the Glasgow prognostic score (GPS), modified GPS (mGPS), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) in relation to CRC outcomes...
March 24, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/28407827/-values-of-neutrophil-lymphocyte-ratio-and-platelet-lymphocyte-ratio-in-predicting-sensitivity-to-intravenous-immunoglobulin-in-kawasaki-disease
#9
Ying-Di Yuan, Jun Sun, Peng-Fei Li, Chun-Lei Wei, Yan-Hui Yu
OBJECTIVE: To study the values of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in predicting the sensitivity to intravenous immunoglobulin (IVIG) in Kawasaki disease (KD). METHODS: A retrospective cohort study was conducted in 404 children with newly diagnosed KD. The data on routine blood tests, NLR, and PLR were collected before and after IVIG treatment. The receiver operating characteristic (ROC) curve was used to determine the cut-off values of NLR and PLR in predicting the insensitivity to IVIG...
April 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28404961/increased-platelet-lymphocyte-ratio-closely-relates-to-inferior-clinical-features-and-worse-long-term-survival-in-both-resected-and-metastatic-colorectal-cancer-an-updated-systematic-review-and-meta-analysis-of-24-studies
#10
Nan Chen, Wanling Li, Kexin Huang, Wenhao Yang, Lin Huang, Tianxin Cong, Qingfang Li, Meng Qiu
Colorectal cancer (CRC) is one of the most common cancers worldwide. However, the prognostic and clinical value of platelet-lymphocyte ratio (PLR) in colorectal cancer was still unclear, which attracted more and more researchers' considerable attention. We performed a systematic review and meta-analysis to investigate the relationship between PLR and survival as well as clinical features of CRC update to September 2016. The hazard ratio (HR) or odds ratio (OR) with 95% confidence interval (CI) were calculated to access the association...
March 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28403106/baseline-serum-albumin-and-other-common-clinical-markers-are-prognostic-factors-in-colorectal-carcinoma-a-retrospective-cohort-study
#11
Sagrario González-Trejo, José F Carrillo, D Darlene Carmona-Herrera, Patricia Baz-Gutiérrez, Roberto Herrera-Goepfert, Gloria Núñez, Francisco J Ochoa-Carrillo, Dolores Gallardo-Rincón, Vincenzo Aiello-Crocifoglio, Luis F Oñate-Ocaña
The aim of the present study was to define the prognostic role of baseline serum albumin (BSA) in colorectal cancer (CRC) across tumor-node-metastasis (TNM) stages and other well defined prognostic factors. Many prognostic models in medicine employ BSA to define or refine treatments in very specific settings; in CRC, BSA has been found to be a prognostic factor as well. A retrospective cohort study of consecutive patients with CRC demonstrated by biopsy, who attended a cancer center during a 7-year period. Multivariate analysis was utilized to define prognostic factors associated with overall survival (OS) employing the Cox model...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28394006/prognostic-value-of-platelet-to-lymphocyte-ratio-in-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#12
Li Hui, Yun Zhou, Yan Ma, Su Xia Han, Lian Suo Zhou
BACKGROUND: The aim of this study was to investigate whether the platelet-to-lymphocyte ratio (PLR) is an independent predictor of all-cause mortality and cardiovascular events in patients with acute coronary syndrome (ACS). METHODS: PubMed, Embase, and the Cochrane Library were searched for relevant cohort studies regarding the association between PLR and outcomes of patients with ACS. Either a random- or a fixed-effect model was used for pooling data. RESULTS: Eight studies involving 6627 patients with ACS were included...
April 10, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28386987/neutrophil-and-platelet-to-lymphocyte-ratios-in-people-with-subjective-mild-cognitive-impairment-and-early-alzheimer-s-disease
#13
Tevfik Kalelioglu, Mehmet Yuruyen, Gozde Gultekin, Hakan Yavuzer, Yadigar Özturk, Meltem Kurt, Yildiray Topcu, Alper Doventas, Murat Emul
No abstract text is available yet for this article.
April 7, 2017: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/28384249/a-systematically-structured-review-of-biomarkers-of-dying-in-cancer-patients-in-the-last-months-of-life-an-exploration-of-the-biology-of-dying
#14
Victoria Louise Reid, Rachael McDonald, Amara Callistus Nwosu, Stephen R Mason, Chris Probert, John E Ellershaw, Séamus Coyle
BACKGROUND: The Neuberger review made a number of recommendations to improve end of life care, including research into the biology of dying. An important aspect of the biology of dying is the identification of biomarkers as indices of disease processes. Biomarkers have the potential to inform the current, limited understanding of the dying process and assist clinicians in recognising dying, in particular how to distinguish dying from reversible acute deterioration. OBJECTIVES: To critically appraise the literature on biological factors that may be used as prognostic indicators in advanced cancer patients and to identify candidate biomarkers of the dying process that can be measured serially in cancer patients' bodily fluids...
2017: PloS One
https://www.readbyqxmd.com/read/28384215/use-of-the-combination-of-the-preoperative-platelet-to-lymphocyte-ratio-and-tumor-characteristics-to-predict-peritoneal-metastasis-in-patients-with-gastric-cancer
#15
Xiao-Dong Chen, Chen-Chen Mao, Rui-Sen Wu, Wei-Teng Zhang, Ji Lin, Xiang-Wei Sun, Chu-Huai Chi, Neng Lou, Peng-Fei Wang, Xian Shen, Guan-Bao Zhu, Shu-Rong Shen
The aims of the present study were to evaluate the predictive value of the platelet-to-lymphocyte ratio for peritoneal metastasis in patients with gastric cancer and to construct an available preoperative prediction system for peritoneal metastasis. A total of 1080 patients with gastric cancer were enrolled in our study. The preoperative platelet-to-lymphocyte ratio and other serum markers and objective clinical tumor characteristics were evaluated by receiver operating characteristic curves. A logistic analysis was performed to determine the independent predictive indicators of peritoneal metastasis...
2017: PloS One
https://www.readbyqxmd.com/read/28382799/elevated-plasma-fibrinogen-levels-and-prognosis-of-epithelial-ovarian-cancer-a-cohort-study-and-meta-analysis
#16
Yanlin Luo, Hee Seung Kim, Miseon Kim, Maria Lee, Yong Sang Song
OBJECTIVE: To evaluate the effect of elevated plasma fibrinogen levels on the prognosis of epithelial ovarian cancer (EOC). METHODS: We reviewed the data of 217 patients with advanced-stage EOC between 2000 and 2012, and investigated the prognostic role of elevated plasma fibrinogen levels compared with serum CA-125 levels, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR). For further evaluation, we performed a meta-analysis using 5 cohort studies published to July 2015, including our cohort study after a literature review...
May 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28380461/are-pretreatment-neutrophil-lymphocyte-ratio-and-platelet-lymphocyte-ratio-useful-in-predicting-the-outcomes-of-patients-with-small-cell-lung-cancer
#17
Min Deng, Xuelei Ma, Xiao Liang, Chenjing Zhu, Manni Wang
OBJECTIVES: The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) have been proved to affect the prognosis of various types of cancers. However, the prognostic role of NLR and PLR in patients with small-cell lung cancer (SCLC) remains controversial. The objective of this study is to assess the prognostic values of NLR, PLR and other potential prognostic indexes in SCLC patients. RESULTS: The optimal cutoff levels were 2.65 for NLR, 125 for PLR and 210 for LDH by ROC curves analysis...
March 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28374931/a-link-between-platelet-to-lymphocyte-ratio-and-helicobacter-pylori-infection
#18
Raymond Farah, Hamza Hamza, Rola Khamisy-Farah
PURPOSE: Chronic Helicobacter pylori gastritis affects two-thirds of the world's population and is one of the most common chronic inflammatory disorders of humans, the infection clearly results in chronic mucosal inflammation in the stomach and duodenum, which, in turn, might lead to abnormalities in gastroduodenal motility and sensitivity and is the most frequent cause of dyspepsia and peptic disease. Some studies showed that there was a correlation between low-grade inflammation as CRP and HP infection...
April 4, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28367174/does-obesity-cause-chronic-inflammation-the-association-between-complete-blood-parameters-with-body-mass-index-and-fasting-glucose
#19
Tuba Tulay Koca
OBJECTIVE: This study aimed to determine the relationship of complete blood count (CBC) parameters and derivates with fasting blood sugar and the body mass index. METHODS: This was a prospective, observational clinical study. Hospitalized patients who received a physiotherapy program in the Physical Medicine and Rehabilitation Clinic between March and June 2016 were included. The age, height, weight, body mass index (BMI), fasting blood glucose, erythrocyte sedimentation (ESR), C-reactive protein, and CBC parameters (leukocytes, platelets, neutrophil, lymphocytes, and monocytes) and red cell distribution width, platelet distribution width, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio of the patients were recorded...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28365200/postoperative-changes-in-neutrophil-to-lymphocyte-ratio-and-platelet%C3%A2-count-a-simple-prognostic-predictor%C3%A2-for-adult-to-adult-living-donor%C3%A2-liver%C3%A2-transplantation
#20
Hironori Hayashi, Hiroyuki Takamura, Yoshinao Ohbatake, Shinichi Nakanuma, Hidehiro Tajima, Sachio Fushida, Ichiro Onishi, Takashi Tani, Koichi Shimizu, Tetsuo Ohta
BACKGROUND/OBJECTIVE: The neutrophil-to-lymphocyte ratio (NLR) is a simple index that represents systemic inflammatory change. The number of platelets is also known to reflect both post-transplant graft regeneration and dysfunction. Thus, we aimed to investigate the usefulness of NLR and platelet number in predicting the clinical course after adult-to-adult living donor liver transplantation (AA-LDLT) in the acute postoperative period in recipients. METHODS: Between January 1999 and December 2013, 61 patients underwent their first AA-LDLT at our institute...
March 29, 2017: Asian Journal of Surgery
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