keyword
MENU ▼
Read by QxMD icon Read
search

behavior modification

keyword
https://www.readbyqxmd.com/read/28822692/complex-clinical-intersection-palliative-care-in-patients-with-dementia
#1
REVIEW
Ellen E Lee, Beverly Chang, Steven Huege, Jeremy Hirst
Because of the rapidly growing older population and increases in longevity, rates of dementia have been rising. Clinical challenges of treating dementia include limited resources and lack of curative therapies. Palliative care approaches improve quality of life and alleviate suffering for dementia patients at the end of life, although implementation may be limited by societal acceptance and feasibility. This review examines the published literature on pain assessments, pain and behavior interventions, tools for advanced care planning, and clinical concerns in dementia patients...
June 29, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28822233/obese-fathers-lead-to-an-altered-metabolism-and-obesity-in-their-children-in-adulthood-review-of-experimental-and-human-studies
#2
REVIEW
Fernanda Ornellas, Priscila V Carapeto, Carlos A Mandarim-de-Lacerda, Marcia B Aguila
OBJECTIVE: To discuss the recent literature on paternal obesity, focusing on the possible mechanisms of transmission of the phenotypes from the father to the children. SOURCES: A non-systematic review in the PubMed database found few publications in which paternal obesity was implicated in the adverse transmission of characteristics to offspring. Specific articles on epigenetics were also evaluated. As the subject is recent and still controversial, all articles were considered regardless of year of publication...
August 16, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28821537/investigating-novice-and-expert-conceptions-of-genetically-modified-organisms
#3
Lisa M Potter, Sarah A Bissonnette, Jonathan D Knight, Kimberly D Tanner
The aspiration of biology education is to give students tools to apply knowledge learned in the classroom to everyday life. Genetic modification is a real-world biological concept that relies on an in-depth understanding of the molecular behavior of DNA and proteins. This study investigated undergraduate biology students' conceptions of genetically modified organisms (GMOs) when probed with real-world, molecular and cellular, and essentialist cues, and how those conceptions compared across biology expertise...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/28816429/smart-cellulose-nanofluids-produced-by-tunable-hydrophobic-association-of-polymer-grafted-cellulose-nanocrystals
#4
Yea Ram Lee, Daehwan Park, Sang Koo Choi, Miju Kim, Heung Soo Baek, Jin Nam, Chan Bok Chung, Chinedum O Osuji, Jin Woong Kim
Cellulose fibrils, unique plant-derived semi-crystalline nanomaterials with exceptional mechanical properties, have significant potential for rheology modification of complex fluids due to their ability to form a physically associated semi-flexible fibrillary network. Here, we report new associative cellulose nanocrystals (ACNCs) with stress-responsive rheological behaviors in an aqueous solution. The surface-mediated living radical polymerization was employed to graft poly (stearyl methacrylate-co-2-methacryloxyethyl phosphorylcholine) brushes onto the nanofibrils, and then 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation was conducted to produce nanoscale ACNCs in the aqueous solution...
August 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28816395/cultural-adaptation-and-validation-of-the-caring-behaviors-assessment-tool-in-chile
#5
Ricardo A Ayala, María Julia Calvo
This study reports the process of cultural adaptation of the Caring Behaviors Assessment tool for the Spanish language, and determine its validity and reliability. We used a mixed-methods approach with a sample of adult participants after translation and adjustment, correlations and multiple regressions were used to explain differences in perception. Internal consistency and reliability were determined by using Cronbach's alpha. While slight modifications to syntax, language, and the interval scale were necessary to enable better comprehension, all items had high average scores as did the seven subscales...
August 17, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28815987/health-related-quality-of-life-in-randomized-controlled-trials-of-lorcaserin-for-obesity-management-what-mediates-improvement
#6
R L Kolotkin, R D Crosby, Z Wang
Lorcaserin, plus diet and exercise, has demonstrated significant weight loss and improved cardiometabolic parameters vs. placebo in patients with overweight/obesity in three randomized, placebo-controlled trials. We examined whether lorcaserin is also associated with greater improvements in health-related quality of life (HRQOL) and whether these improvements are wholly attributable to weight loss. Pooled data from Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM), Behavioral Modification and Lorcaserin Second Study for Obesity Management (BLOSSOM) and BLOOM-Diabetes Mellitus (BLOOM-DM) trials were analysed (n = 5624)...
August 17, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28815905/degradable-vanadium-disulfide-nanostructures-with-unique-optical-and-magnetic-functions-for-cancer-theranostics
#7
Yuyan Chen, Liang Cheng, Ziliang Dong, Yu Chao, Huali Lei, He Zhao, Jian Wang, Zhuang Liu
Multifunctional biodegradable inorganic theranostic nano-agents are of great interests to the field of nanomedicine. Herein, VS2 nanosheets upon lipid modification could be converted into ultra-small VS2 nanodots encapsulated inside polyethylene glycol (PEG) modified lipid micelles. Owing to the paramagnetic property, high near-infrared (NIR) absorbance, and chelator-free 99mTc4+ labeling of VS2, such VS2@lipid-PEG nanoparticles could be used for T1-weighted magnetic resonance (MR), photoacoustic (PA),and single photon emission computed tomography (SPECT) tri-modal imaging guided photothermal ablation of tumors...
August 16, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28815055/green-lacewings-neuroptera-chrysopidae-are-commonly-associated-with-a-diversity-of-rickettsial-endosymbionts
#8
Michael Gerth, Ronny Wolf, Christoph Bleidorn, Julia Richter, Rebekka Sontowski, Jasmin Unrein, Martin Schlegel, Axel Gruppe
BACKGROUND: Bacterial symbionts transmitted from mothers to offspring are found in the majority of arthropods. Numerous studies have illustrated their wide impact on host biology, such as reproduction, behavior, and physiology One of the most common inherited symbionts is Rickettsia spp. (Alphaproteobacteria, Rickettsiales), which are found in about one-quarter of terrestrial arthropods, as well as in other invertebrates. In insect populations, Rickettsia spp. have been reported to cause reproductive modifications and fecundity-enhancing effects...
2017: Zoological Letters
https://www.readbyqxmd.com/read/28814400/mediation-and-modification-of-genetic-susceptibility-to-obesity-by-eating-behaviors
#9
Blandine de Lauzon-Guillain, Emma Ad Clifton, Felix R Day, Karine Clément, Soren Brage, Nita G Forouhi, Simon J Griffin, Yves Akoli Koudou, Véronique Pelloux, Nicholas J Wareham, Marie-Aline Charles, Barbara Heude, Ken K Ong
Background: Many genetic variants show highly robust associations with body mass index (BMI). However, the mechanisms through which genetic susceptibility to obesity operates are not well understood. Potentially modifiable mechanisms, including eating behaviors, are of particular interest to public health.Objective: Here we explore whether eating behaviors mediate or modify genetic susceptibility to obesity.Design: Genetic risk scores for BMI (BMI-GRSs) were calculated for 3515 and 2154 adults in the Fenland and EDEN (Etude des déterminants pré et postnatals de la santé et du développement de l'enfant) population-based cohort studies, respectively...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28813589/regulation-of-stability-on-histone-h2a-h2b-dimer-by-h2a-tyr57-phosphorylation
#10
Takuma Sueoka, Gosuke Hayashi, Akimitsu Okamoto
Histone H2A and H2B form a H2A-H2B heterodimer, which is a fundamental unit of nucleosome assembly and disassembly. Several posttranslational modifications change the interface between the H2A-H2B dimer and the H3-H4 tetramer, and regulate nucleosome stability. However, posttranslational modifications associated with the interface between H2A and H2B have not been discussed. In this paper, it is shown that Tyr57 phosphorylation in H2A strongly influences H2A-H2B dimerization. Tyr57-phosphorylated H2A was chemically synthesized and utilized to reconstitute the H2A-H2B dimer and nucleosome as well as canonical H2A...
August 16, 2017: Biochemistry
https://www.readbyqxmd.com/read/28811267/app-a%C3%AE-structural-diversity-and-alzheimer-s-disease-pathogenesis
#11
REVIEW
Alex E Roher, Tyler A Kokjohn, Steven G Clarke, Michael R Sierks, Chera L Maarouf, Geidy E Serrano, Marwan S Sabbagh, Thomas G Beach
The amyloid cascade hypothesis of Alzheimer's disease (AD) proposes amyloid- β (Aβ) is a chief pathological element of dementia. AD therapies have targeted monomeric and oligomeric Aβ 1-40 and 1-42 peptides. However, alternative APP proteolytic processing produces a complex roster of Aβ species. In addition, Aβ peptides are subject to extensive posttranslational modification (PTM). We propose that amplified production of some APP/Aβ species, perhaps exacerbated by differential gene expression and reduced peptide degradation, creates a diverse spectrum of modified species which disrupt brain homeostasis and accelerate AD neurodegeneration...
August 12, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28810775/chemical-dynamics-between-wells-across-a-time-dependent-barrier-self-similarity-in-the-lagrangian-descriptor-and-reactive-basins
#12
Andrej Junginger, Lennart Duvenbeck, Matthias Feldmaier, Jörg Main, Günter Wunner, Rigoberto Hernandez
In chemical or physical reaction dynamics, it is essential to distinguish precisely between reactants and products for all times. This task is especially demanding in time-dependent or driven systems because therein the dividing surface (DS) between these states often exhibits a nontrivial time-dependence. The so-called transition state (TS) trajectory has been seen to define a DS which is free of recrossings in a large number of one-dimensional reactions across time-dependent barriers and thus, allows one to determine exact reaction rates...
August 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28810485/risk-perception-self-efficacy-trust-for-physician-depression-and-behavior-modification-in-diabetic-patients
#13
Hissei Imai, Toshiaki A Furukawa, Shin-U Hayashi, Atsushi Goto, Kazuo Izumi, Yasuaki Hayashino, Mitsuhiko Noda
We evaluated the associations of risk perception, self-efficacy, and trust with two health promotion behaviors (food habits and exercise) and depressive mood. Diabetic patients aged between 40 and 64 ( n = 1195) were included in the analyses. Risk perception worsened behavioral changes in terms of food habits and depression, whereas self-efficacy and trust improved food habits, exercise, and depression; trust improved exercise and depression. In conclusion, self-efficacy and trust appear to be more beneficial than risk perception for positive behavioral changes and for improving depression in diabetic patients...
July 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809838/easy-manipulation-of-architectures-in-protein-based-hydrogels-for-cell-culture-applications
#14
Nicholas Bodenberger, Dennis Kubiczek, Frank Rosenau
Hydrogels are recognized as promising materials for cell culture applications due to their ability to provide highly hydrated cell environments. The field of 3D templates is rising due to the potential resemblance of those materials to the natural extracellular matrix. Protein-based hydrogels are particularly promising because they can easily be functionalized and can achieve defined structures with adjustable physicochemical properties. However, the production of macroporous 3D templates for cell culture applications using natural materials is often limited by their weaker mechanical properties compared to those of synthetic materials...
August 4, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28809769/adverse-experiences-in-childhood-and-sexually-transmitted-infection-risk-from-adolescence-into-adulthood
#15
Stephanie London, Kelly Quinn, Joy D Scheidell, B Christopher Frueh, Maria R Khan
BACKGROUND: Childhood maltreatment, particularly sexual abuse, has been found to be associated with sexual risk behaviors later in life. We aimed to evaluate associations between a broad range of childhood traumas and sexual risk behaviors from adolescence into adulthood. METHODS: Using data from Waves I, III and IV of the National Longitudinal Study of Adolescent to Adult Health (Add Health), we used logistic regression to estimate the unadjusted odds ratio (OR) and adjusted OR (AOR) for associations between 9 childhood traumas and a cumulative trauma score and three sexual risk outcomes (multiple partnerships, sex trade involvement, and sexually transmitted infection [STI]) in adolescence, young adulthood, and adulthood...
September 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28809430/a-one-step-method-for-the-functional-and-property-modification-of-dopa-based-nanocoatings
#16
Qinghua Lyu, Jieyu Zhang, Koon Gee Neoh, Christina Li Lin Chai
Biomimetic poly(catecholamine) coatings have gained much attention in recent years due to their versatility as functional materials. Despite this, only limited methods are available to modify the function and property of poly(catecholamine) coatings, primarily through post-modification methods. Our approach reported herein provides a simple approach to the fabrication of novel functionalized poly(catecholamine) coatings. The strategy employs the copolymerization of N-Ac-3,4-dihydroxyphenylalanine methyl ester (NADOPAMe) with nucleophilic additives, giving rise to nano-coatings on various surfaces including plastic, metal, glass and polymers...
August 15, 2017: Nanoscale
https://www.readbyqxmd.com/read/28807795/d-cycloserine-facilitates-extinction-learning-and-enhances-extinction-related-brain-activation
#17
Anne Klass, Benjamin Glaubitz, Martin Tegenthoff, Silke Lissek
Extinction learning is modulated by N-methyl D-aspartate receptors (NMDAR) particularly in prefrontal and hippocampal brain regions. The use of of NMDA agonists in exposure therapy of anxiety disorders has been investigated in various patient groups. Behavioral results showed beneficial effects of pre-learning administration of the partial NMDAR agonist D-Cycloserine (DCS) on therapy success. However, the impact of DCS upon non-fear-related contextual extinction, and associated recruitment of extinction-relevant brain regions is as yet unknown...
August 11, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28806641/acute-ethanol-administration-results-in-a-protective-cytokine-and-neuroinflammatory-profile-in-traumatic-brain-injury
#18
Akila Chandrasekar, Florian Olde Heuvel, Annette Palmer, Birgit Linkus, Albert C Ludolph, Tobias M Boeckers, Borna Relja, Markus Huber-Lang, Francesco Roselli
Ethanol intoxication is a common comorbidity in traumatic brain injury. To date, the effect of ethanol on TBI pathogenic cascades and resulting outcomes remains debated. A closed blunt weight-drop murine TBI model has been implemented to investigate behavioral (by sensorimotor and neurological tests), and neuro-immunological (by tissue cytokine arrays and immuno-histology) effects of ethanol intoxication on TBI. The effect of the occurrence of traumatic intracerebral hemorrhage was also studied. The results indicate that ethanol pretreatment results in a faster and better recovery after TBI with reduced infiltration of leukocytes and reduced microglia activation...
August 11, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28806136/harnessing-olig2-function-in-tumorigenicity-and-plasticity-to-target-malignant-gliomas
#19
Jennifer Kosty, Fanghui Lu, Robert Kupp, Shwetal Mehta, Q Richard Lu
Glioblastoma (GBM) is the most prevalent and malignant brain tumor, displaying notorious resistance to conventional therapy, partially due to molecular and genetic heterogeneity. Understanding the mechanisms for gliomagenesis, tumor stem/progenitor cell propagation and phenotypic diversity is critical for devising effective and targeted therapy for this lethal disease. The basic helix-loop-helix transcription factor OLIG2, which is universally expressed in gliomas, has emerged as an important player in GBM cell reprogramming, genotoxic resistance, and tumor phenotype plasticity...
August 14, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28804467/learning-about-expectation-violation-from-prediction-error-paradigms-a-meta-analysis-on-brain-processes-following-a-prediction-error
#20
Lisa D'Astolfo, Winfried Rief
Modifying patients' expectations by exposing them to expectation violation situations (thus maximizing the difference between the expected and the actual situational outcome) is proposed to be a crucial mechanism for therapeutic success for a variety of different mental disorders. However, clinical observations suggest that patients often maintain their expectations regardless of experiences contradicting their expectations. It remains unclear which information processing mechanisms lead to modification or persistence of patients' expectations...
2017: Frontiers in Psychology
keyword
keyword
6967
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"