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Maximal lactate state

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https://www.readbyqxmd.com/read/29368654/identifying-individual-animal-factors-associated-with-mycobacterium-avium-subsp-paratuberculosis-map-milk-elisa-positivity-in-dairy-cattle-in-the-midwest-region-of-the-united-states
#1
Gustavo Machado, Kaushi Kanankege, Val Schumann, Scott Wells, Andres Perez, Julio Alvarez
BACKGROUND: Mycobacterium avium subsp. paratuberculosis (MAP) is a widespread chronic disease of ruminants that causes severe economic losses to the dairy cattle industry worldwide. The objective of this study was to evaluate the association between individual cow MAP-ELISA and relevant milk production predictors in dairy cattle using data routinely collected as part of quality and disease control programs in the Midwest region of the U.S. Milk ELISA results of 45,652 animals from 691 herds from November 2014 to August 2016 were analyzed...
January 25, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29290449/lactation-response-to-soybean-meal-and-rumen-protected-methionine-supplementation-of-corn-silage-based-diets
#2
H Nursoy, M Gonzalez Ronquillo, A P Faciola, G A Broderick
Corn silage, an important forage fed to dairy cows in the United States, is energy rich but protein poor. The objectives of this experiment were to investigate the effects on production of milk and milk components of feeding corn silage-based diets with 4 levels of dietary crude protein (CP) plus rumen-protected methionine (RPM). Thirty-six cows were blocked by days in milk into 9 squares and randomly assigned to 9 balanced 4 × 4 Latin squares with four 4-wk periods. All diets were formulated to contain, as a percent of dry matter (DM), 50% corn silage, 10% alfalfa silage, 4% soyhulls, 2...
December 28, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29163332/clinical-use-of-cerebral-microdialysis-in-patients-with-aneurysmal-subarachnoid-hemorrhage-state-of-the-art
#3
REVIEW
Raimund Helbok, Mario Kofler, Alois Josef Schiefecker, Maxime Gaasch, Verena Rass, Bettina Pfausler, Ronny Beer, Erich Schmutzhard
Objective: To review the published literature on the clinical application of cerebral microdialysis (CMD) in aneurysmal subarachnoid hemorrhage (SAH) patients and to summarize the evidence relating cerebral metabolism to pathophysiology, secondary brain injury, and outcome. Methods: Study selection: Two reviewers identified all manuscripts reporting on the clinical use of CMD in aneurysmal SAH patients from MEDLINE. All identified studies were grouped according to their focus on brain metabolic changes during the early and subacute phase after SAH, their association with mechanisms of secondary brain injury and outcome...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29161112/reply-to-discussion-of-can-measures-of-critical-power-precisely-estimate-the-maximal-metabolic-steady-state-is-it-still-necessary-to-compare-critical-power-to-maximal-lactate-steady-state-when-is-it-appropriate-to-compare-critical-power-to-maximal-lactate-steady
#4
Daniel A Keir, Felipe Mattioni Maturana, Juan M Murias
No abstract text is available yet for this article.
November 21, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29161111/discussion-of-can-measures-of-critical-power-precisely-estimate-the-maximal-metabolic-steady-state-is-it-still-necessary-to-compare-critical-power-to-maximal-lactate-steady-state
#5
Ricardo Dantas de Lucas
No abstract text is available yet for this article.
November 21, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29148629/carbohydrate-mouth-rinse-improves-cycling-performance-carried-out-until-the-volitional-exhaustion
#6
Bruno Bavaresco Gambassi, Ylana Gomes de Santana Barros Leal, Edson R Pinheiro Dos Anjos, Bruna A Antonelli, Daniela C Gomes Gonçalves E Silva, Iracema H Pires de Mélo Montenegro, Rita di Cássia de Oliveira Angelo, Isis S Correia Moura, Paulo A Schwingel
BACKGROUND: Carbohydrates (CHO) are among the most investigated nutritional ergogenic aids, and may be consumed in different forms, e.g., mouth rinse with carbohydrate solution (MRCS). In this sense, the aim of this study was to evaluate the impact of MRCS on the performance of physically active individuals undergoing a physical exercise session carried out until the volitional exhaustion. METHODS: This is a counter-balanced randomized study, with a double-blind design...
November 17, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29035635/effects-of-varying-the-step-duration-on-the-determination-of-lactate-thresholds-in-elite-rowers
#7
Pitre C Bourdon, Sarah M Woolford, Jonathan D Buckley
This study aimed to identify the minimum increment duration required to accurately assess two distinct lactate thresholds. Twenty-one elite rowers (12 female, 9 males) each performed 8-9 rowing tests comprising: 1) five progressive incremental tests (3, 4, 5, 7 or 10 min steps); and 2) at least three 30-min constant-intensity maximal lactate steady state (MLSS) assessments. Power output (PO) at lactate threshold 1 (LT1) was higher in the 3- and 4-min incremental tests. No other measures were different for LT1...
October 16, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28952829/mental-fatigue-and-physical-and-cognitive-performance-during-a-two-bout-exercise-test
#8
Susan Vrijkotte, Romain Meeusen, Cloe Vandervaeren, Luk Buyse, Jeroen van Cutsem, Nathalie Pattyn, Bart Roelands
PURPOSE: The two bout exercise protocol has been developed to diagnose non-functional overreaching (NFO) and the 'Overtraining Syndrome' (OTS). It consists of two maximal exercise bouts separated by 4 hours. Mental fatigue negatively influences performance but the effects of its occurrence during the two bout exercise protocol have never been investigated. The aim of this study was to examine whether mental fatigue (induced during the rest period) influences physical and cognitive performance during/after the second exercise bout of the two bout exercise protocol...
September 27, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28712262/evaluation-of-efforts-in-untrained-wistar-rats-following-exercise-on-forced-running-wheel-at-maximal-lactate-steady-state
#9
Sajjad Rezaei, Hamid Agha-Alinejad, Mahdieh Molanouri Shamsi, Mahvash Jafari, Fabricio Azevedo Voltarelli, Alireza Naderi, Conrad Earnest
PURPOSE: We aimed to examine the effect of running speed on metabolic responses associated with maximal lactate steady state (MLSS) in rats during forced running wheel (FRW) exercise. METHODS: Forty male adult Wistar rats were divided into seven groups. The blood lactate threshold and peak running speed were determined for an incremental power test group. Five groups participated in constant power tests at intensities 10, 13, 14.5, 16, and 17.5 m/min to determine MLSS and a non-exercise group was chosen as the control...
March 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28642717/the-lactate-minimum-test-concept-methodological-aspects-and-insights-for-future-investigations-in-human-and-animal-models
#10
REVIEW
Leonardo H D Messias, Claudio A Gobatto, Wladimir R Beck, Fúlvia B Manchado-Gobatto
In 1993, Uwe Tegtbur proposed a useful physiological protocol named the lactate minimum test (LMT). This test consists of three distinct phases. Firstly, subjects must perform high intensity efforts to induce hyperlactatemia (phase 1). Subsequently, 8 min of recovery are allowed for transposition of lactate from myocytes (for instance) to the bloodstream (phase 2). Right after the recovery, subjects are submitted to an incremental test until exhaustion (phase 3). The blood lactate concentration is expected to fall during the first stages of the incremental test and as the intensity increases in subsequent stages, to rise again forming a "U" shaped blood lactate kinetic...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28593171/withania-somnifera-targets-interleukin-8-and-cyclooxygenase-2-in-human-prostate-cancer-progression
#11
Anand Setty Balakrishnan, Abel Arul Nathan, Mukesh Kumar, Sudhakar Ramamoorthy, Sathish Kumar Ramia Mothilal
BACKGROUND: Prostate cancer (PC) is a common noncutaneous malignancy in men. The incidence of PC is increasing at an alarming rate across the globe. Progression of PC is associated with elevated levels of interleukin-8 (IL-8) and cyclooxygenase-2 (COX-2) in malignant cells. Overexpression of these players is accompanied by chronic inflammation, increased angiogenesis, proliferation, migration, and inhibition of apoptosis. Moreover, their elevated circulating levels promote the disease progression from androgen-dependent to androgen-independent state...
June 2017: Prostate International
https://www.readbyqxmd.com/read/28583599/serum-concentration-dynamic-of-energy-homeostasis-hormones-leptin-insulin-thyroid-hormones-and-cortisol-throughout-canine-pregnancy-and-lactation
#12
L Cardinali, A Troisi, J P Verstegen, L Menchetti, A Elad Ngonput, C Boiti, S Canello, R Zelli, A Polisca
Pregnancy and lactation represent critical periods of canine reproductive life and different hormones are required to maintain homeostasis and the correct energy requirements. The aim of this study was to evaluate leptin, insulin, triiodotyronine (T3), thyroxin (T4) and cortisol serum concentrations to better describe the canine maternal energy metabolism. Twelve Bloodhound bitches that had at least one litter and were considered to be healthy submitted blood samples every 15 days starting from day 0 (ovulation) throughout pregnancy up to the end of lactation (day 120)...
July 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28526448/the-catechol-o-methyltransferase-inhibitors-tolcapone-and-entacapone-uncouple-and-inhibit-the-mitochondrial-respiratory-chain-in-heparg-cells
#13
David Grünig, Andrea Felser, Jamal Bouitbir, Stephan Krähenbühl
The catechol-O-methyltransferase inhibitor tolcapone causes hepatotoxicity and mitochondrial damage in animal models. We studied the interaction of tolcapone with mitochondrial respiration in comparison to entacapone in different experimental models. In HepaRG cells (human cell-line), tolcapone decreased the ATP content (estimated IC50 100±15μM) and was cytotoxic (estimated IC50 333±45μM), whereas entacapone caused no cytotoxicity and no ATP depletion up to 200μM. Cytochrome P450 induction did not increase the toxicity of the compounds...
May 16, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28499395/time-course-of-blood-lactate-levels-inflammation-and-mitochondrial-function-in-experimental-sepsis
#14
Thiago Domingos Corrêa, Adriano José Pereira, Sebastian Brandt, Madhusudanarao Vuda, Siamak Djafarzadeh, Jukka Takala, Stephan Mathias Jakob
BACKGROUND: A decrease in blood lactate levels (Lac) >10% during the first hours of resuscitation in sepsis is associated with better outcomes, but the mechanisms are unclear. Our objective was to investigate the relationship between the time course of Lac, inflammatory response, and mitochondrial respiration during experimental sepsis. METHODS: Original data from two previously published studies were reanalyzed. In cohort 1, pigs were randomized to be resuscitated for 48 h starting at 6, 12, and 24 h, respectively, after fecal peritonitis induction (n = 8 each)...
May 12, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28489460/a-preliminary-study-in-the-alterations-of-mitochondrial-respiration-in-patients-with-carbon-monoxide-poisoning-measured-in-blood-cells
#15
David H Jang, Matthew Kelly, Kevin Hardy, David S Lambert, Frances S Shofer, David M Eckmann
OBJECTIVES: Carbon monoxide (CO) is a colorless and odorless gas responsible for poisoning mortality and morbidity in the United States. At this time, there is no reliable method to predict the severity of poisoning or clinical prognosis following CO exposure. Whole blood cells, such as peripheral blood mononuclear cells (PBMCs) and platelets, have been explored for their potential use to act as sensitive biomarkers for mitochondrial dysfunction which may have a role in CO poisoning. DESIGN: The objective of this study was to measure mitochondrial respiration using intact cells obtained from patients exposed to CO as a potential biomarker for mitochondrial inhibition with results that can be obtained in a time frame useful for guiding clinical care...
July 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28488826/soccer-training-high-intensity-interval-training-is-mood-disturbing-while-small-sided-games-ensure-mood-balance
#16
Okba Selmi, Monoem Haddad, Lina Majed, Wissam Ben Khalifa, Marzougui Hamza, Karim Chamari
BACKGROUNDː The aim of the study was to compare the effects of high-intensity intermittent training (HIIT) versus small-sided games (SSG) in soccer on both the physiological responses and the mood state of players. METHODS: Sixteen professional soccer players took part in the study (age: 24.1±0.9 years). Testing of players was conducted on separate days in a randomized and counter-balanced order (each training session: 28-min: 4x4 minutes work with 3-min of passive recovery in-between)...
May 9, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28345160/increasing-skeletal-muscle-carnitine-availability-does-not-alter-the-adaptations-to-high-intensity-interval-training
#17
Christopher E Shannon, Reza Ghasemi, Paul L Greenhaff, Francis B Stephens
Increasing skeletal muscle carnitine availability alters muscle metabolism during steady-state exercise in healthy humans. We investigated whether elevating muscle carnitine, and thereby the acetyl-group buffering capacity, altered the metabolic and physiological adaptations to 24 weeks of high-intensity interval training (HIIT) at 100% maximal exercise capacity (Wattmax ). Twenty-one healthy male volunteers (age 23±2 years; BMI 24.2±1.1 kg/m(2) ) performed 2 × 3 minute bouts of cycling exercise at 100% Wattmax , separated by 5 minutes of rest...
March 27, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28302463/critical-power-testing-or-self-selected-cycling-which-one-is-the-best-predictor-of-maximal-metabolic-steady-state
#18
Felipe Mattioni Maturana, Daniel A Keir, Kaitlin M McLay, Juan M Murias
Critical power (CP) demarcates the boundary between heavy and very heavy exercise intensity domains, and therefore, the power output (PO) that can be sustained at the maximal metabolic steady-state during constant-PO exercise (i.e., maximal lactate steady-state (MLSS)). However, the estimated CP does not always reflect a sustainable intensity of exercise, where blood lactate concentration ([La]) and oxygen uptake (V˙O2) reach a plateau. OBJECTIVES: To test cyclists' ability to predict their highest PO associated with metabolic steady-state based on their own perception of effort...
January 24, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28282663/reliability-and-validity-of-a-new-specific-field-test-of-aerobic-capacity-with-the-ball-for-futsal-players
#19
Ricardo Barbieri, Fabio Barbieri, Fabio Milioni, Julio Dos-Santos, Marcelo Soares, Alessandro Zagatto, Marcelo Papoti
The aim of this study was to establish the validity and reliability and verification of the reproducibility of the lactate minimum test (LM) to predict the maximal lactate steady state exercise intensity (MLSS) on a futsal-specific circuit (Futsal_circuit) which takes into consideration the technical movements performed. 16 male Brazilian futsal players (body mass: 67.7±8.3 kg; height: 1.73±0.05 m) were distributed randomly into 2 studies with 8 athletes in each (Study A - reproducibility; Study B - validity)...
March 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28245246/oxygen-uptake-kinetics-and-energy-system-s-contribution-around-maximal-lactate-steady-state-swimming-intensity
#20
Jailton Gregório Pelarigo, Leandro Machado, Ricardo Jorge Fernandes, Camila Coelho Greco, João Paulo Vilas-Boas
The purpose of this study was to examine the oxygen uptake ([Formula: see text]) kinetics and the energy systems' contribution at 97.5, 100 and 102.5% of the maximal lactate steady state (MLSS) swimming intensity. Ten elite female swimmers performed three-to-five 30 min submaximal constant swimming bouts at imposed paces for the determination of the swimming velocity (v) at 100%MLSS based on a 7 x 200 m intermittent incremental protocol until voluntary exhaustion to find the v associated at the individual anaerobic threshold...
2017: PloS One
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