keyword
https://read.qxmd.com/read/37286267/reduction-of-disease-activity-corticosteroids-use-and-healthcare-resource-utilisation-in-patients-with-systemic-lupus-erythematosus-treated-with-belimumab-in-clinical-practice-settings-observe-spain-multicentre-study
#1
MULTICENTER STUDY
Josefina Cortés-Hernández, Carlos Marras Fernández-Cid, Jose Luis Andreu Sánchez, Jaime Calvo Alén, Angel M García-Aparicio, Elvira Díez Álvarez, Francisco Javier Hidalgo Bermejo, Carlos Coronell, Alessandra Perna, Josep Ordi Ros
INTRODUCTION AND OBJECTIVES: This OBSErve Spain study, a part of the international OBSErve programme, evaluated belimumab real-world use and effectiveness following 6 months of treatment in patients with active systemic lupus erythematosus (SLE) in clinical practice in Spain. MATERIALS AND METHODS: In this retrospective, observational study (GSK Study 200883), eligible patients with SLE receiving intravenous belimumab (10mg/kg) had their disease activity (physician assessed), SELENA-SLEDAI scores, corticosteroid use, and healthcare resource utilisation (HCRU), assessed after 6 months of treatment versus index (belimumab initiation) or 6 months pre-index...
2023: Reumatología clinica
https://read.qxmd.com/read/35940560/-translated-article-randomized-placebo-controlled-double-blind-clinical-trial-to-evaluate-efficacy-and-safety-of-topical-tranexamic-acid-in-saving-blood-loss-in-patients-undergoing-prosthetic-knee-surgery
#2
JOURNAL ARTICLE
F Oliva-Moya, I Belloso-Moreno, J M Vilches-Fernández, M Casas-Ruiz, J A Andrés-García
BACKGROUND AND OBJECTIVE: Knee arthroplasty is a major surgery with potential significant blood loss. Assess the efficacy and safety of topical administration of 3g of tranexamic acid (TXA) in terms of reducing blood loss in knee arthroplasty. MATERIAL AND METHOD: A randomized, phase III, double-blind, placebo-controlled clinical trial has been conducted. We included 150 patients in 2 parallel treatment groups (75 per arm). The solution was administered topically intra-articular after cementation and prior to capsular closure...
August 6, 2022: Revista Española de Cirugía Ortopédica y Traumatología
https://read.qxmd.com/read/35867922/budget-impact-analysis-of-primary-screening-with-the-hpv-test-and-genotyping-against-conventional-cytology-in-colombia
#3
JOURNAL ARTICLE
Miguel Amézquita, Geny Carolina Silva, Diego Antonio Restrepo, Linda Margarita Ibata, Rafael Niño, Maximiliano Bustacara, Víctor Alexander Sáenz, Dieric Anderson Díaz, Milena Alarcón, Luz Adriana Quintero
Introduction: The detection of the human papillomavirus (HPV) through the combination of the HPV test and other techniques such as cytology has impacted the detection and timely treatment of lesions associated with cervical cancer. Objective: To estimate the budgetary impact of the strategy of early detection of HPV with DNA test genotyping with reflex cytology versus conventional cytology in women aged 30 to 65 years attending the cervical cancer screening program at a health benefit managing entity in Colombia...
June 1, 2022: Biomédica: Revista del Instituto Nacional de Salud
https://read.qxmd.com/read/35452861/randomized-placebo-controlled-double-blind-clinical-trial-to-evaluate-efficacy-and-safety-of-topical-tranexamic-acid-in-saving-blood-loss-in-patients-undergoing-prosthetic-knee-surgery
#4
JOURNAL ARTICLE
F Oliva-Moya, I Belloso-Moreno, J M Vilches-Fernández, M Casas-Ruiz, J A Andrés-García
OBJECTIVE: Knee arthroplasty is a major surgery with potential significant blood loss. Assess the efficacy and safety of topical administration of 3 gr of tranexamic acid (TXA) in terms of reducing blood loss in knee arthroplasty. MATERIAL AND METHOD: A randomized, phase III, double-blind, placebo-controlled clinical trial has been conducted. We included 150 patients in two parallel treatment groups (75 per arm). The solution was administered topically intra-articular after cementation and prior to capsular closure...
April 19, 2022: Revista Española de Cirugía Ortopédica y Traumatología
https://read.qxmd.com/read/35394941/cost-consequences-of-age-and-comorbidity-in-accelerated-postoperative-discharge-after-colectomy
#5
JOURNAL ARTICLE
Ana C De Roo, Sarah P Shubeck, Anne H Cain-Nielsen, Edward C Norton, Scott E Regenbogen
BACKGROUND: Prospective payment models have incentivized reductions in length of stay after surgery. The benefits of abbreviated postoperative hospitalization could be undermined by increased readmissions or postacute care use, particularly for older adults or those with comorbid conditions. OBJECTIVE: The purpose of this study was to determine whether hospitals with accelerated postsurgical discharge accrue total episode savings or incur greater postdischarge payments among patients stratified by age and comorbidity...
May 1, 2022: Diseases of the Colon and Rectum
https://read.qxmd.com/read/33658168/influence-of-intra-articular-tranexamic-acid-on-cost-savings-and-early-functional-outcomes-in-total-knee-arthroplasty
#6
JOURNAL ARTICLE
A C Urgel Granados, A Torres Campos, M Royo Agustín, A Rillo Lázaro, M T Espallargas Donate, Á Castro Sauras
BACKGROUND AND AIM: Total knee arthroplasty (TKA) is a frequent intervention that can associate significant blood loss. There are several methods to avoid transfusions. One of the most relevant is tranexamic acid (TXA). Our purpose is to analyse the efficacy in terms of blood savings, transfusion needs, functional results, and cost-effectiveness of intra-articular (IA) administration in TKA. MATERIALS AND METHODS: We conducted a retrospective analysis of historical cohorts (75 patients each) between January 2015 and December 2016...
February 28, 2021: Revista Española de Cirugía Ortopédica y Traumatología
https://read.qxmd.com/read/32969888/a-paradigm-shift-in-physician-reimbursement-a-model-to-align-reimbursement-to-value-in-laparoscopic-colorectal-surgery-in-the-united-states
#7
JOURNAL ARTICLE
Deborah S Keller, Jianying Zhang, Scott R Steele
BACKGROUND: Despite common beliefs, underuse of laparoscopic colorectal surgery remains an issue. A paradigm shift to increase laparoscopy and align payment with effort is needed, with pressures to improve value. OBJECTIVE: The purpose of this study was to compare reimbursement across surgical approach and payer for common colorectal procedures and to propose a novel way to increase use in the United States. DATA SOURCES: Centers for Medicare & Medicaid Services (Medicare) reimbursement and commercial claims data from 2012 to 2015 were used...
October 2020: Diseases of the Colon and Rectum
https://read.qxmd.com/read/31189321/-notes-on-the-cost-effectiveness-of-nutritional-therapy-with-oral-supplementation-in-the-integral-recovery-of-the-patient-with-mrd
#8
REVIEW
Julia Álvarez
The efficient management of health services requires obtaining the highest level of health possible with the available resources. The health economy has developed in recent years under the pressure of a more demanding population, older and with more comorbidities, in an environment of limited resources and greater financing difficulties. The Economics of Nutrition was born as a new discipline that addresses aspects related to the role of economics and nutrition in the health of healthy and sick populations...
July 1, 2019: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/30356960/the-messinian-stromatolites-of-the-sierra-del-colmenar-western-mediterranean-facies-characterization-and-sedimentological-interpretation
#9
JOURNAL ARTICLE
Patricio Guillermo Villafañe, Hugo Corbí, Carlos Cónsole-Gonella, Francisco Javier Ruiz-Sánchez, Jesús Miguel Soria
A representative outcrop of the Messinian stromatolites belonging to the Terminal Carbonate Complex unit, from the northern sector of the Bajo Segura basin ( Caja de Ahorros del Mediterraneo section, Sierra del Colmenar, SE Spain) has been studied. Here, we present a detailed analysis of the architecture, external morphology, and internal morphology in order to reconstruct the environmental and palaeoecological conditions for their growth. The stromatolites macrostructure consists of a continuously doming type morphology (build up and sheets areas)...
2018: PeerJ
https://read.qxmd.com/read/30226494/-seguridad-y-eficacia-del-modelo-de-atenci%C3%A3-n-fast-track-vs-atenci%C3%A3-n-convencional-en-apendicitis-no-complicada-del-paciente-pedi%C3%A3-trico
#10
RANDOMIZED CONTROLLED TRIAL
Alberto Tlacuilo-Parra, Sandy P López-Valenzuela, Gabriela Ambriz-González, Elizabeth Guevara-Gutiérrez
OBJETIVO: Comparar la seguridad y la eficacia de la atención fast-track vs. atención convencional en apendicitis no complicada en un hospital pediátrico. MÉTODO: Ensayo clínico controlado, aleatorizado, con dos grupos de 30 pacientes cada uno: A) fast-track, apendicitis no complicada que cumplieron el programa; y B) atención convencional, apendicitis no complicada con atención habitual. Variables de seguridad y eficacia: proporción de complicaciones y tiempo de estancia hospitalaria...
2018: Cirugia y Cirujanos
https://read.qxmd.com/read/28474699/-what-can-doctors-do-to-moderate-healthcare-costs
#11
EDITORIAL
Alberto Lifshitz, Miguel Ángel Celis, Mucio Moreno, Héctor Aguirre Gas, José Halabe, Luis Jasso, Óscar Arrieta, Rubén Burgos, Carlos Campillo, Manuel de la Llata, Judith Domínguez, Sergio Islas, Ricardo Plancarte, Alejandro Reyes, Antonio Soda, Emma Verásteguio, Julio Sotelo
Los costos de la atención médica pueden alcanzar niveles tales que marginen a algunos pacientes de los beneficios del avance científico y tecnológico. Las razones de estos elevados costos son diversas y en la mayoría de los casos no está en manos de los médicos moderarlos. En este escrito se proponen algunas acciones que los médicos podemos realizar para disminuir los costos de la atención médica. La magnitud del ahorro que se puede alcanzar con estas medidas es modesta, puesto que la mayor parte de los costos no dependen de los médicos, pero se trata de ofrecer nuestra contribución...
March 2017: Gaceta Médica de México
https://read.qxmd.com/read/28000471/-not-available
#12
JOURNAL ARTICLE
Leticia Goni, Maritza Aray Miranda, J. Alfredo Martínez, Marta Cuervo
Introduction: The assessment of intake and eating habits become increasingly important to relate them to the risk of disease. In this sense, food frequency questionnaires (FFQ) are a common dietary tool used in both clinical practice and nutritional epidemiological studies. Objective: The aim of the study was the validation of a food groups frequency questionnaire (FGFQ) based on an exchange system, in relation to a 7 days food record (FR) used as reference. Methods: A total of 60 healthy adults (males and females) were recruited...
November 29, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/26199356/viral-exposures-and-ms-outcome-in-a-prospective-cohort-of-children-with-acquired-demyelination
#13
JOURNAL ARTICLE
Naila Makhani, Brenda Banwell, Raymond Tellier, Carmen Yea, Suzanne McGovern, Julia O'Mahony, Jean M Ahorro, Douglas Arnold, A Dessa Sadovnick, Ruth A Marrie, Amit Bar-Or
Epstein-Barr virus (EBV) infection is associated with increased multiple sclerosis (MS) risk. Recently, cytomegalovirus (CMV) infection has been proposed as a protective factor against MS development. We determined EBV, herpes simplex virus, varicella-zoster virus and CMV seroprevalence in 247 prospectively followed children with acquired demyelinating syndromes (ADS). Remote EBV infection was more common in children with MS than those with monophasic ADS while CMV infection was more common in children with monophasic ADS...
March 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://read.qxmd.com/read/26049212/implementation-of-a-patient-blood-management-program-in-pediatric-scoliosis-surgery
#14
JOURNAL ARTICLE
A Pérez-Ferrer, E Gredilla-Díaz, J de Vicente-Sánchez, F Sánchez Pérez-Grueso, F Gilsanz-Rodríguez
OBJECTIVES: To determine whether the implementation of a blood conservation program, and the adoption and progressive association of different methods, reduces transfusion requirements in pediatric patients undergoing scoliosis surgery of different origins. MATERIAL AND METHOD: Quasi-experimental, nonrandomized, descriptive study, approved by the Ethics Committee for Research of our institution. 50 pediatric patients (ASA I-III) aged 5 to 18 years, undergoing scoliosis surgery of any etiology by a single posterior or double approach (anterior and posterior) were included...
February 2016: Revista Española de Anestesiología y Reanimación
https://read.qxmd.com/read/25601893/how-do-management-fees-affect-retirement-wealth-under-mexico-s-personal-retirement-accounts-system
#15
JOURNAL ARTICLE
Emma Aguila, Michael D Hurd, Susann Rohwedder
In 1997, Mexico transformed its pay-as-you-go social security system to a fully funded system with personal retirement accounts, including management fees. This article examines changes in retirement wealth resulting from this new system. It shows that management fees have drained a significant proportion of individuals' retirement wealth and have increased the number of persons claiming a government-subsidized minimum pension, particularly from the time the system was introduced in 1997 until adjustment to management fees in 2008...
December 2014: Latin American Policy
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