Junichi Ishigami, Mayank Kansal, Rupal Mehta, Anand Srivastava, Mahboob Rahman, Mirela Dobre, Sadeer G Al-Kindi, Alan S Go, Sankar D Navaneethan, Jing Chen, Jiang He, Zeenat Yousuf Bhat, Bernard G Jaar, Lawrence J Appel, Kunihiro Matsushita
RATIONALE & OBJECTIVE: Heart-kidney crosstalk is recognized as the cardiorenal syndrome. We examined the association of cardiac function and structure with the risk of kidney failure with replacement therapy (KFRT) in a chronic kidney disease (CKD) population. STUDY DESIGN: Prospective observational cohort study. SETTING & PARTICIPANTS: 3,027 participants from the Chronic Renal Insufficiency Cohort Study. EXPOSURE: Five preselected variables that assess different aspects of cardiac structure and function: left ventricular mass index (LVMI), LV volume, left atrial (LA) area, peak tricuspid regurgitation (TR) velocity, and left ventricular ejection fraction (EF) as assessed by echocardiography...
March 18, 2023: American Journal of Kidney Diseases