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https://www.readbyqxmd.com/read/27790430/screening-for-intestinal-colonization-with-vancomycin-resistant-enterococci-and-associated-risk-factors-among-patients-admitted-to-an-adult-intensive-care-unit-of-a-large-teaching-hospital
#1
Rajesh Amberpet, Sujatha Sistla, Subhash Chandra Parija, Molly Mary Thabah
INTRODUCTION: Gut colonization with Vancomycin Resistant Enterococci (VRE) increases the risk of acquiring infection during hospital stay. Patients admitted in the ICU's are the major reservoirs for VRE colonization due to higher antibiotic pressure. AIM: To determine the rate of VRE colonization among patients admitted in the Medical Intensive Care Unit (MICU) and to assess the various risk factors which are associated with VRE colonization. MATERIALS AND METHODS: This was a prospective study carried out over a period of 18 months from September 2013 to February 2015 in the Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER), Pondicherry, South India...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27651706/the-three-rs-of-written-assessment-the-jipmer-experience
#2
EDITORIAL
S Manikandan, B Gitanjali
No abstract text is available yet for this article.
July 2016: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/27630838/identification-of-streptococcus-pyogenes-phenotypic-tests-vs-molecular-assay-spy1258pcr-a-comparative-study
#3
Tintu Abraham, Sujatha Sistla
INTRODUCTION: Traditionally Group A Streptococcus pyogenes (GAS) is differentiated from other beta haemolytic streptococci (BHS) by certain presumptive tests such as bacitracin sensitivity and production of Pyrollidonyl Aryl Sulfatase (PYR). The phenotypic and genotypic confirmatory tests are Lancefield grouping for cell wall carbohydrate antigen and PCR for spy1258 gene respectively. Reliance on presumptive tests alone may lead to misidentification of isolates. AIM: To compare the predictive values of routine phenotypic tests with spy1258 PCR for the identification of Streptococcus pyogenes...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27520889/maternal-and-birth-risk-factors-for-children-screening-positive-for-autism-spectrum-disorders-on-m-chat-r
#4
Saranya Ravi, Venkatesh Chandrasekaran, Shivanand Kattimani, Mahadevan Subramanian
This study was carried out to screen children aged 16-30 months, attending pediatric outpatient department of JIPMER, Puducherry, during June to August 2014, for ASD using modified checklist for autism in toddlers-revised (MCHAT-R) and to find association between maternal, birth and postnatal risk factors with risk of ASD. A total of 350 mother-child pairs with children aged between 16 and 30 months were recruited. M-CHAT-R was administered to all mothers to screen for ASD along with risk checklist. Based on screen result children were classified as ASD (high risk) and no ASD (low and medium risk) group...
August 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27437217/global-dna-methylation-level-among-ciprofloxacin-resistant-clinical-isolates-of-escherichia-coli
#5
Thiyagarajan Yugendran, Belgode Narasimha Harish
INTRODUCTION: Fluoroquinolone resistant clinical isolates belonging to the family Enterobacteriaceae is a major public health concern in India. Data analysis in JIPMER hospital revealed 10% rise in fluoroquinolone resistance within a span of three years suggestive of the possible involvement of mechanism/s other than QRDR capable of imparting fluoroquinolone resistance. DNA methylation regulates gene expression. Moreover, methylated cytosine is a mutational hotspot. Thus, DNA methylation can alter bacterial gene expression profile as well as facilitate the bacteria in accumulating mutations possibly leading to increased antimicrobial resistance...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27222806/sequence-analysis-of-pfcrt-and-pfmdr1-genes-and-its-association-with-chloroquine-resistance-in-southeast-indian-plasmodium-falciparum-isolates
#6
Hiasindh Ashmi Antony, Sindhusuta Das, Subhash Chandra Parija, Sanghamitra Padhi
BACKGROUND: Due to the widespread resistance of Plasmodium falciparum to chloroquine drug, artemisinin-based combination therapy (ACT) has been recommended as the first-line treatment. This study aims to evaluate the extent of chloroquine resistance in P. falciparum infection after the introduction of ACT. This study was carried out based on the mutation analysis in P. falciparum chloroquine resistant transporter (pfcrt) and P. falciparum multidrug resistance 1 (pfmdr1) genes. Identification of these molecular markers plays a significant role in monitoring and assessment of drug resistance as well as in designing an effective antimalarial drug policy in India...
June 2016: Genomics Data
https://www.readbyqxmd.com/read/27190798/evaluation-of-ns1-antigen-detection-for-early-diagnosis-of-dengue-in-a-tertiary-hospital-in-southern-india
#7
Ashwini Manoor Anand, Sujatha Sistla, Rahul Dhodapkar, Abdoul Hamide, Niranjan Biswal, Badrinath Srinivasan
INTRODUCTION: Dengue is a mosquito-borne disease affecting mainly tropical and subtropical regions of the world. The early diagnosis of dengue is required for identifying an epidemic and also for implementing effective vector control measures. AIM: To evaluate NS1 antigen assay as an alternative to RT-PCR for the early diagnosis of Dengue. MATERIALS AND METHODS: A comparative study was conducted to evaluate NS1 antigen assay in clinically suspected dengue cases admitted to JIPMER hospital from January to November 2011...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27168994/high-incidence-of-plasmid-mediated-quinolone-resistance-genes-among-ciprofloxacin-resistant-clinical-isolates-of-enterobacteriaceae-at-a-tertiary-care-hospital-in-puducherry-india
#8
Thiyagarajan Yugendran, Belgode Narasimha Harish
Background. Plasmid-mediated quinolone resistance (PMQR) has received considerable attention recently. Data analysis in Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER) revealed 75% of the Enterobacteriaceae isolates to be ciprofloxacin-resistant in 2012. Few reports regarding the prevalence of PMQR are available from India. Hence, the present study was carried out to ascertain the prevalence of PMQR genes among clinical isolates of ciprofloxacin-resistant Enterobacteriaceae in JIPMER...
2016: PeerJ
https://www.readbyqxmd.com/read/27050177/honey-on-oral-mucositis-a-randomized-controlled-trial
#9
J L Jayalekshmi, R Lakshmi, A Mukerji
BACKGROUND AND OBJECTIVE: The main stream of management of head and neck cancer is by radiotherapy and surgery. During radiation therapy in head and neck cancers, oral cavity is directly exposed to high dose radiation which leads to several side effects - oral mucositis being the most distressing one. This study was intended to assess the effects of applying honey on oral mucositis during radiation therapy. MATERIAL AND METHODS: The research design used in this study was Randomized Control Trial with single blinding method in the Radiotherapy Unit of Regional Cancer Centre (RCC), at JIPMER...
January 2016: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/26884655/an-analysis-of-the-origins-subjects-and-awards-received-for-presentations-at-the-annual-iasg-conferences-2009-2013
#10
Subhash Soni, Peush Sahni, Samiran Nundy
s presented at scientific meetings are important for making ongoing research more widely known and may also reflect the quality of the parent institution's standard of patient care. We analyzed the abstracts presented at the annual meetings of IASG for the past 5 years for (i) medium of presentation (oral/poster/videos), (ii) subjects discussed, (iii) institution of origin, (iv) whether a prospective/ retrospective study or a case report, (v) changing trends, and (vi) awards received. Of the 1340 abstracts analyzed, there were 18...
December 2015: Indian Journal of Surgery
https://www.readbyqxmd.com/read/26634184/abductor-hallucis-anatomical-variation-and-its-clinical-implications-in-the-reconstruction-of-chronic-nonhealing-ulcers-and-defects-of-foot
#11
Ravi Kumar Chittoria, Harsha Pratap, Suma Hottigoudar Yekappa
Abductor hallucis (AH) is an intrinsic muscle of sole of the foot. It is commonly used in the coverage of ankle and heel defects and chronic nonhealing ulcers of the foot; its use is reported to have a favorable long-term outcome. The muscle's apt bulk and size, its simple surgical isolation, absence of donor-site defect, unvaried anatomy, and long neurovascular pedicle are some of the advantages that make it a promising muscle flap. During routine cadaver dissection in the Department of Anatomy of Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India, we identified an anatomical variation in AH in both feet of a 45-year-old embalmed male Indian cadaver...
December 1, 2015: Advances in Wound Care
https://www.readbyqxmd.com/read/26604603/morbidity-profile-and-out-of-pocket-health-care-expenditure-among-under-five-children-of-an-urban-area-of-puducherry
#12
Divya Nair, Sitanshu Sekhar Kar, Kalaiselvi Selvaraj, Archana Ramalingam
BACKGROUND: Information on out of pocket (OOP) health care expenditure is essential for health planning and devising strategies for Universal Health Coverage (UHC). AIMS AND OBJECTIVES: To describe morbidity profile, treatment preferences and OOP expenditure toward health care of under five children in an urban primary health center of Puducherry. MATERIALS AND METHODS: A cross-sectional study was conducted in four Anganwadi centers selected randomly from a total of 13 centers in the urban service area of JIPMER, Puducherry...
August 2015: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/26372084/high-serum-testosterone-levels-during-postpartum-period-are-associated-with-postpartum-depression
#13
A Aswathi, Soundravally Rajendiren, Archana Nimesh, R Ravi Philip, Shivanand Kattimani, D Jayalakshmi, P H Ananthanarayanan, Pooja Dhiman
In view of the reported cases of mood disorders that occur in mothers following childbirth and believing that sex steroid hormones contribute to mood and behavioral changes, this study has been aimed to explore the role of sex steroid hormones as an etiological factor for postpartum depression (PPD). This study was conducted at JIPMER, Puducherry, India between January 2010 and 2011. 103 women were recruited in the study after childbirth, out of which 62 women who were believed to be suffering from PPD were categorized as cases and the remaining 41 with no mood changes as controls, using Edinburgh Postpartum Depression Scale (EPDS) (cases had EPDS score ≥10 at 24-28h, controls had score <10 at 24-48h postpartum)...
October 2015: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/26037430/student-centred-learning-in-community-medicine-an-experience-from-jawaharlal-institute-of-postgraduate-medical-education-and-research-puducherry
#14
S S Kar, K C Premarajan, Subitha L, R Archana, S Iswarya, Sujiv A
BACKGROUND: Student-centred learning (SCL) places the student at the centre of policies, practices and decision-making in the teaching-learning process. SCL methodology also advocates active involvement of students in the curriculum planning, selection of teaching-learning methods and assessment process. We planned an education innovation project to assess the perception of fifth semester undergraduate medical students towards implementation of an SCL methodology. METHODS: The study was done among 87 fifth semester undergraduate medical students (batch of 2010-11) in the noncommunicable disease epidemiology section of Community Medicine at the Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry...
September 2014: National Medical Journal of India
https://www.readbyqxmd.com/read/25859453/relationship-between-antimicrobial-consumption-and-the-incidence-of-antimicrobial-resistance-in-escherichia-coli-and-klebsiella-pneumoniae-isolates
#15
Noyal Mariya Joseph, B Bhanupriya, Deepak Gopal Shewade, Belgode Narasimha Harish
INTRODUCTION: Gram negative organisms are one of the major causes of nosocomial diseases. Development of resistance to antibiotics by these organisms increases their risk in clinical treatment of patients. It also affects morbidity and mortality hence needs to be monitored and controlled. AIM: The aim of the present study was to analyse the correlation between consumption of parenteral antibiotics and the rates of antimicrobial resistance among the Escherichia coli and Klebsiella pneumoniae isolates collected during Dec 2010 - Jun 2013 from JIPMER hospital...
February 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/25738014/comparison-of-ranolazine-and-trimetazidine-on-glycemic-status-in-diabetic-patients-with-coronary-artery-disease-a-randomized-controlled-trial
#16
Selvarajan Sandhiya, Steven Aibor Dkhar, Ajith Ananthakrishna Pillai, Melvin George, Balachander Jayaraman, Adithan Chandrasekaran
INTRODUCTION: Cardiovascular diseases have become the leading cause of death around the globe and diabetes mellitus (DM) is considered to be a coronary artery disease (CAD) risk equivalent. Ranolazine, an anti anginal drug has been found to reduce Glycated haemoglobin (HbA1c) in diabetes patients with chronic angina. However the effect of another antianginal drug trimetazidine, on glycemic status is not clear. AIM: To compare the effect of ranolazine and trimetazidine on glycemic status in diabetic patients with CAD...
January 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/25709349/adverse-drug-reactions-of-imatinib-in-patients-with-chronic-myeloid-leukemia-a-single-center-surveillance-study
#17
Jose Francis, Muthiah Palaniappan, Biswajit Dubashi, Suresh Chandra Pradhan, Adithan Chandrasekaran
OBJECTIVE: To monitor the adverse drug reactions (ADRs) associated with imatinib treatment in patients with chronic myeloid leukemia (CML) in a tertiary care hospital. MATERIALS AND METHODS: The study was carried out by the Departments of Pharmacology and Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India. The study was carried out from March 2012 to February 2014. The ADRs were reported in a suspected Adverse Drug Reaction Reporting form, provided by the Central Drugs Standard Control Organization (CDSCO), Ministry of Health and Family Welfare, Government of India...
January 2015: Journal of Pharmacology & Pharmacotherapeutics
https://www.readbyqxmd.com/read/25584214/detection-of-salmonella-in-blood-by-pcr-using-irob-gene
#18
Vithiya Ganesan, Belgode Narasimha Harish, Godfred Antony Menezes, Subash Chandra Parija
BACKGROUND: Salmonella, a genus of more than 2500 serological variants (serovars), includes many organisms that can cause human disease. Enteric fever remains an important public health problem in developing countries. Non typhoidal Salmonella generally produce a self limited gastroenteritis in healthy individuals whereas in extremes of age and immunocompromised cause severe fatal disease. The protean manifestations make this disease a true diagnostic challenge. AIM: The present study was carried out to optimize PCR for detecting the Salmonella genus using iroB gene and evaluate its use in the rapid diagnosis of typhoid and non typhoidal salmonellosis...
November 2014: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/25508307/an-analysis-of-adverse-drug-reactions-to-radiographic-contrast-media-reported-during-a-3-year-period-in-a-tertiary-care-hospital-in-south-india
#19
A Subathra, S Sandhiya, R Kesavan
AIM: The aim of this study was to analyse the nature and incidence of adverse drug reactions to radiographic contrast media (ionic and non ionic) reported during a 3 year period in a tertiary care hospital in South India METHODS: Adverse Drug Reactions (ADRs) to radiographic contrast media (ionic and non ionic) reported during a 3 year period to the pharmacovigilance centre, JIPMER, Pondicherry were retrospectively analysed for demographic profile, frequency, severity, causality and the temporal relationship of contrast administratior to the occurrence of ADR...
January 2014: Indian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/25464676/an-analysis-of-adverse-drug-reactions-to-radiographic-contrast-media-reported-during-a-3-year-period-in-a-tertiary-care-hospital-in-south-india
#20
A Subathra, S Sandhiya, R Kesavan
AIM: The aim of this study was to analyse the nature and incidence of adverse drug reactions to radiographic contrast media (ionic and non ionic) reported during a 3 year period in a tertiary care hospital in South India METHODS: Adverse Drug Reactions (ADRs) to radiographic contrast media (ionic and non ionic) reported during a 3 year period to the pharmacovigilance centre, JIPMER, Pondicherry were retrospectively analysed for demographic profile, frequency, severity, causality and the temporal relationship of contrast administratior to the occurrence of ADR...
January 2014: Indian Journal of Physiology and Pharmacology
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