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https://www.readbyqxmd.com/read/27924295/dataset-on-the-physical-characterization-of-biopolymer-coated-magnetic-nanoparticles
#1
Shazia Bano, Muhammad Afzal
The data presented in this article is related to the research article entitled "Paclitaxel loaded magnetic nanocomposites with folate modified chitosan/carboxymethyl surface; a vehicle for imaging and targeted drug delivery" (S. Bano, M. Afzal, M.M. Waraich, K. Alamgir, S. Nazir, 2016) [1]. It contains the absorbance spectra, band gap energies of pure nickel-ferrite nano cores (NFs), and calibration curve of Paclitaxel. Thermal stability analysis of pure NFs, chitosan (CS) and carboxymethyl cellulose (CMC)-conjugated NFs samples is also included in the data...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27924250/first-carpo-metacarpal-joint-arthritis-interpositional-arthroplasty-using-trapezium
#2
Chirag Kapoor, Ankur Kansagra, Maulik Jhaveri, Aditya Merh, Paresh Golwala
Thumb pain secondary to arthritis at the basal joint of the thumb is a common condition, especially in women, and can be quite disabling. An accurate diagnosis can be readily made from the history and examination. Reconstructive procedures for each stage of the disease are aimed at relieving pain and restoring thumb motion and strength. There are a number of methods available to treat this condition both conservatively and surgically with variable success rates. We present a case of a middle-aged female with first carpo-metacarpal (CMC) joint arthritis in whom we have tried a new technique in which the trapezium is excised, crushed, put in a sponge covering and then inserted back in the void created after excision...
November 3, 2016: Curēus
https://www.readbyqxmd.com/read/27923406/ameliorative-effects-of-rutin-against-metabolic-biochemical-and-hormonal-disturbances-in-polycystic-ovary-syndrome-in-rats
#3
Sarwat Jahan, Faryal Munir, Suhail Razak, Anam Mehboob, Qurat Ul Ain, Hizb Ullah, Tayyaba Afsar, Ghazala Shaheen, Ali Almajwal
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women of reproductive age. The study was commenced to assess the favorable effects of Rutin against metabolic, biochemical, histological, and androgenic aspects of polycystic ovary syndrome in rats. METHODS: Female Sprague-Dawley rats were administered letrozole (1 mg/kg) per orally (p.o) for a period of 21 days for the induction of PCOS, followed by dose of rutin (100 mg/kg and 150 mg/kg, p...
December 7, 2016: Journal of Ovarian Research
https://www.readbyqxmd.com/read/27917834/the-crystal-structure-of-the-endoglucanase-cel10-a-family-8-glycosyl-hydrolase-from-klebsiella-pneumoniae
#4
Ayman Attigani, Lifang Sun, Qing Wang, Yadan Liu, Dingping Bai, Shengping Li, Xiaohong Huang
Cellulases are produced by microorganisms that grow on cellulose biomass. Here, a cellulase, Cel10, was identified in a strain of Klebsiella pneumoniae isolated from Chinese bamboo rat gut. Analysis of substrate specificity showed that Cel10 is able to hydrolyze amorphous carboxymethyl cellulose (CMC) and crystalline forms of cellulose (Avicel and xylan) but is unable to hydrolyze p-nitrophenol β-D-glucopyranoside (p-NPG), proving that Cel10 is an endoglucanase. A phylogenetic tree analysis indicates that Cel10 belongs to the glycoside hydrolase 8 (GH8) subfamily...
December 1, 2016: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/27917581/micelle-enhanced-spectrofluorimetric-method-for-quantification-of-entacapone-in-tablets-and-human-plasma
#5
F Belal, F Ibrahim, Z A Sheribah, H Alaa
In this paper, a simple and highly sensitive spectrofluorimetric method was developed and validated for the determination of entacapone (ETC). The proposed method is based on forming a highly fluorescent product through the reduction of ETC with Zn/HCl. The produced fluorophore exhibits strong fluorescence at λem 345 nm after excitation at λex 240 nm. The use of fluorescence enhancers such as Tween-80 and carboxy methyl cellulose (CMC) greatly enhanced the fluorescence of the produced fluorophore by 150% and 200%, respectively...
December 5, 2016: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/27917440/solid-flocculation-and-emulsifying-activities-of-the-lipopolysaccharide-produced-by-trichosporon-mycotoxinivorans-cla2
#6
Vitor S Domingues, Andrea S Monteiro, Gabriella Freitas Ferreira, Vera L Santos
The objective of this study was to evaluate the capability of a lipopolysaccharide, produced by Trichosporon mycotoxinivorans CLA2 using residue of biodiesel processing, to flocculate two different solids in suspension. In addition, the emulsifying activity and the stability of this lipopolysaccharide in response to pH and temperature variations and in the presence of some electrolytes were evaluated. The lipopolysaccharide was used in concentrations ranging from 20 to 80 mgL(-1) to flocculate 100 gL(-1) of kaolin and 50 gL(-1) of charcoal...
December 5, 2016: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/27916941/autoimmune-regulator-expression-in-dc2-4-cells-regulates-the-nf-%C3%AE%C2%BAb-signaling-and-cytokine-expression-of-the-toll-like-receptor-3-pathway
#7
Jitong Sun, Kunwei Niu, Haiying Fu, Haijun Li, Yi Li, Wei Yang
Autoimmune regulator (Aire) mutations result in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), which manifests as multi-organ autoimmunity and chronic mucocutaneous candidiasis (CMC). Indendritic cells (DCs), pattern recognition receptors (PRR), such as Toll-like receptors (TLRs), are closely involved in the recognition of various pathogens, activating the intercellular signaling pathway, followed by the activation of transcription factors and the expression of downstream genes, which take part in mediating the immune response and maintaining immune tolerance...
December 1, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27916424/caring-for-children-with-medical-complexity-perspectives-of-primary-care-providers
#8
Carolyn C Foster, Rita Mangione-Smith, Tamara D Simon
OBJECTIVE: To describe typical care experiences and key barriers and facilitators to caring for children with medical complexity (CMC) from the perspective of community primary care providers (PCPs). STUDY DESIGN: PCPs participating in a randomized controlled trial of a care-coordination intervention for CMC were sent a 1-time cross-sectional survey that asked PCPs to (1) describe their experiences with caring for CMC; (2) identify key barriers affecting their ability to care for CMC; and (3) prioritize facilitators enhancing their ability to provide care coordination for CMC...
December 2, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27901208/gastric-and-renal-effects-of-cox-2-selective-and-non-selective-nsaids-in-rats-receiving-low-dose-aspirin-therapy
#9
Marcella Goetz Moro, Paula Katherine Vargas Sanchez, Mayara Vitorino Gevert, Emeline Maria Baller, Ana Flávia Tostes, Ana Caroline Lupepsa, Sinvaldo Baglie, Gilson Cesar Nobre Franco
The consumption of low-dose aspirin (LDA) to prevent cardiovascular disease continues to increase worldwide. Consequently, the number of chronic LDA users seeking dental procedures that require complementary acute anti-inflammatory medication has also grown. Considering the lack of literature evaluating this interaction, we analyzed the gastric and renal effects caused by a selective COX-2 inhibitor (etoricoxib) and a non-selective COX-2 inhibitor (ibuprofen) nonsteroidal anti-inflammatory drug (NSAID) in rats receiving chronic LDA therapy...
November 28, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27901170/bilayer-hydrogel-actuators-with-tight-interfacial-adhesion-fully-constructed-from-natural-polysaccharides
#10
Jiangjiang Duan, Xichao Liang, Kunkun Zhu, Jinhua Guo, Lina Zhang
Smart hydrogel actuators with excellent biocompatibility and biodegradation are extremely desired for biomedical applications. Herein, we have constructed bio-hydrogel actuators inspired by the bilayer structures of plant organs from chitosan and cellulose/carboxymethylcellulose (CMC) solution in an alkali/urea aqueous system containing epichlorohydrin (ECH) as a crosslinker, and demonstrated tight adhesion between two layers through strong electrostatic attraction and chemical crosslinking. The bilayer hydrogels with excellent mechanical properties could carry out rapid, reversible, and repeated self-rolling deformation actuated by pH-triggered swelling/deswelling, and transformed into rings, tubules, and flower-, helix-, bamboo-, and wave-like shapes by effectively designing the geometric shape and size...
November 30, 2016: Soft Matter
https://www.readbyqxmd.com/read/27900528/the-thermophilic-biomass-degrading-fungus-thielavia-terrestris-co3bag1-produces-a-hyperthermophilic-and-thermostable-%C3%AE-1-4-xylanase-with-exo-and-endo-activity
#11
Yolanda García-Huante, Maribel Cayetano-Cruz, Alejandro Santiago-Hernández, Claudia Cano-Ramírez, Rodolfo Marsch-Moreno, Jorge E Campos, Guillermo Aguilar-Osorio, Claudia G Benitez-Cardoza, Sergio Trejo-Estrada, María Eugenia Hidalgo-Lara
A hyperthermophilic and thermostable xylanase of 82 kDa (TtXynA) was purified from the culture supernatant of T. terrestris Co3Bag1, grown on carboxymethyl cellulose (CMC), and characterized biochemically. TtXynA showed optimal xylanolytic activity at pH 5.5 and at 85 °C, and retained more than 90% of its activity at a broad pH range (4.5-10). The enzyme is highly thermostable with a half-life of 23.1 days at 65 °C, and active in the presence of several metal ions. Circular dichroism spectra strongly suggest the enzyme gains secondary structures when temperature increases...
November 29, 2016: Extremophiles: Life Under Extreme Conditions
https://www.readbyqxmd.com/read/27899004/the-influence-of-binders-and-solvents-on-the-stability-of-ru-ruox-oer-catalyst-nanoparticles-on-ito-nanocrystals-in-cycled-li-o2-battery-cathodes
#12
Svetoslava Vankova, Carlotta Francia, Julia Amici, Juqin Zeng, Silvia Bodoardo, Nerino Penazzi, Gillian Collins, Hugh Geaney, Colm O'Dwyer
Li-O2 battery research at a fundamental level remains critical, and nature of reactions and stability are paramount for realising the promise of the Li-O2 system. We report that ITO nanocrystals with supported 1-2 nm OER catalyst Ru/RuOx nanoparticles demonstrate efficient OER processes, significantly reducing the cell's recharge overpotential, and maintain catalytic activity to promote a consistent cycling discharge potential in Li-O2 cells even when the ITO support nanocrystals deteriorate from the very first cycle...
November 29, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27895702/ameliorating-effect-of-erxian-decoction-combined-with-fructus-schisandrae-chinensis-wu-wei-zi-on-menopausal-sweating-and-serum-hormone-profiles-in-a-rat-model
#13
Shi Wei Wang, Fei Hua Wu, Yan Bo Zhang, Liang Zhang, Jing Su, Hei Kei Wong, Ai Hua Liu, Ho Pan Cheung, Tzi Bun Ng, Yao Tong, Stephen Cho Wing Sze
BACKGROUND: Modified Erxian decoction (MEXD), i.e., Erxian decoction (EXD) with Fructus Schisandrae chinensis (Wu Wei Zi) added, has been used to alleviate menopausal symptoms. This study aimed to investigate the effects of MEXD on menopausal sweating and serum hormone levels in a rat model of menopause after oral administration of MEXD. METHODS: Quality control of MEXD was conducted by employing a reversed-phase high performance liquid chromatography column. The three treatment groups received oral administration of MEXD in 0...
2016: Chinese Medicine
https://www.readbyqxmd.com/read/27895469/comparison-of-bile-salt-phosphatidylcholine-mixed-micelles-in-solubilization-to-sterols-and-stability
#14
Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin, Haiyan Hu
Androst-3β,5α,6β-triol (Triol) is a promising neuroprotective agent, but its poor solubility restricts its development into parenteral preparations. In this study, Triol is significantly solubilized by bile salt/phosphatidylcholine mixed micelles (BS/PC-MM). All BS/PC-MM systems are tested to remarkably improve the drug solubility with various stabilities after drug loading. Among them, the sodium glycocholate (SGC)/egg phosphatidylcholine (EPC) system with 2:1 ratio in weight and the total concentration of SGC and EPC of 100 mg/mL is proved to produce stable mixed micelles with high drug loading...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27888734/production-and-characterization-of-rhamnolipid-using-palm-oil-agricultural-refinery-waste
#15
Mohd Nazren Radzuan, Ibrahim M Banat, James Winterburn
In this research we assess the feasibility of using palm oil agricultural refinery waste as a carbon source for the production of rhamnolipid biosurfactant through fermentation. The production and characterization of rhamnolipid produced by Pseudomonas aeruginosa PAO1 grown on palm fatty acid distillate (PFAD) under batch fermentation were investigated. Results show that P. aeruginosa PAO1 can grow and produce 0.43gL(-1) of rhamnolipid using PFAD as the sole carbon source. Identification of the biosurfactant product using mass spectrometry confirmed the presence of monorhamnolipid and dirhamnolipid...
November 16, 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27880962/production-of-cellulases-by-rhizopus-stolonifer-from-glucose-containing-media-based-on-the-regulation-of-transcriptional-regulator-cre
#16
Yingyiing Zhang, Bin Tang, Guocheng Du
Carbon catabolite repression is a crucial regulation in microorganism, while its characteristic in Rhizopus is unclear now. We extracted a carbon regulation gene cre that encoded a carbon catabolite repressor protein (CRE) from Rhizopus stolonifer TP-02, and studied the regulation of CRE by real-time qPCR. CRE responded to the glucose in a certain range, wherein it could significantly regulate part of cellulases genes (eg, bg and cbh2) without cbh1. Compared with the responding of cre and four cellulases genes to the carboxymethylcellulose sodium (CMC) and the simple carbon source (lactose), the effect of CRE was only related to the concentration of reducing sugars...
November 23, 2016: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27877155/weak-and-saturable-protein-surfactant-interactions-in-the-denaturation-of-apo-%C3%AE-lactalbumin-by-acidic-and-lactonic-sophorolipid
#17
Kell K Andersen, Brian S Vad, Sophie Roelants, Inge N A van Bogaert, Daniel E Otzen
Biosurfactants are of growing interest as sustainable alternatives to fossil-fuel-derived chemical surfactants, particularly for the detergent industry. To realize this potential, it is necessary to understand how they affect proteins which they may encounter in their applications. However, knowledge of such interactions is limited. Here, we present a study of the interactions between the model protein apo-α-lactalbumin (apo-aLA) and the biosurfactant sophorolipid (SL) produced by the yeast Starmerella bombicola...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27874277/graphite-lini0-5mn1-5o4-cells-based-on-environmentally-friendly-in-water-made-electrodes
#18
Francesca De Giorgio, Nina Laszczynski, Jan von Zamory, Marina Mastragostino, Catia Arbizzani, Stefano Passerini
The performance of graphite//LiNi0.5Mn1.5O4 (LNMO) cells whose both electrodes are made using water-soluble sodium carboxymethyl cellulose (CMC) binder is reported for the first time. The full cell performed outstandingly at 400 cycles in the conventional electrolyte ethylene carbonate: dimethyl carbonate - 1M LiPF6 and the delivered specific energy at the 100th, 200th, 300th and 400th cycle corresponded to 82%, 78%, 73% and 66% of the initial energy value of 259 Wh kg-1 referred to the sum of the two electrode composite weights...
November 22, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27870934/remediation-of-hexavalent-chromium-spiked-soil-by-using-synthesized-iron-sulfide-particles
#19
Yujie Li, Wanyu Wang, Liqiang Zhou, Yuanyuan Liu, Zakaria A Mirza, Xiang Lin
Carboxymethyl cellulose (CMC) stabilized microscale iron sulfide (FeS) particles were synthesized and applied to remediate hexavalent chromium (Cr(VI)) spiked soil. The effects of parameters including dosage of FeS particles, soil moisture, and natural organic matter (NOM) in soil were investigated with comparison to iron sulfate (FeSO4). The results show that the stabilized FeS particles can reduce Cr(VI) and immobilize Cr in soil quickly and efficiently. The soil moisture ranging from 40% to 70% and NOM in soil had no significant effects on Cr(VI) remediation by FeS particles...
November 18, 2016: Chemosphere
https://www.readbyqxmd.com/read/27867275/improved-oral-bioavailability-of-total-flavonoids-of-dracocephalum-moldavica-via-composite-phospholipid-liposomes-preparation-in-vitro-drug-release-and-pharmacokinetics-in-rats
#20
Cheng Zeng, Wen Jiang, Meie Tan, Jianguo Xing, Chenghui He
BACKGROUND: Dracocephalum moldavica L is a traditional Uygur medicine for centuries, total flavonoids extracted from Dracocephalum moldavica are the major active ingredients of herbs, which possesses significant medicinal values to treat coronart disease and hypertension, due to the glycosyl group on the ring, total flavonoids of Dracocephalum moldavica has low hydrophilic and poorly absorbed after oral administration, so one way is the formulation of poorly water soluble and permeabledrugs with lipids containing formulations such as Composite phospholipid liposomes to improve the absorption profile of drug...
October 2016: Pharmacognosy Magazine
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