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Preeti Singh, Manju Agrawal, Rajesh Hishikar, Usha Joshi, Basant Maheshwari, Ajay Halwai
BACKGROUND: India is a developing country and adverse drug reactions (ADRs) influence most of the diseases in our population, and monitoring is required due to the paucity of ADRs. The present study was done to analyze the ADRs at the ADR monitoring center (AMC) of tertiary care hospital in Raipur during 1 year. MATERIALS AND METHODS: Study of ADR monitoring of outpatient and inpatient was a prospective and observational study carried out between September 2015 and August 2016...
November 2017: Indian Journal of Pharmacology
Sukhpal Kaur, Amarjeet Singh, Manoj K Tewari, Tejinder Kaur
Background: More than 80% of bedridden patients develop bedsores in home care settings. Training of informal caregivers can significantly affect the quality of care to these patients. Objective: The objective of this study is to compare the effectiveness of two caregiver training strategies on prevention of bedsores among bedridden patients. Methods: The study was carried out in Chandigarh. The study center was at PGIMER, Chandigarh. Seventy-eight bedridden patients being taken care in their homes were identified...
January 2018: Indian Journal of Palliative Care
Anita Tahlan, Neelam Varma, Shano Naseem, Deepak Bansal, Jogeshwar Binota, Anil Sood, Man Updesh Singh Sachdeva, Pankaj Malhotra, Subhash Varma
Chronic myelogenous leukemia (CML) is a rare disease in children, accounting for approximately 3% of leukemias in children and adolescents, with an annual incidence of 1 case per million children in western countries. This study was conducted, at PGIMER, Chandigarh. Ninety eight patients, 48 in children and adolescents group, and 50 in adult group were included in the study. Their hematological profiles along with the bone marrow findings were analyzed. The diagnosis of CML was confirmed by cytogenetics and/or molecular analysis...
January 2018: Indian Journal of Hematology & Blood Transfusion
Vivek Lal, Manoj K Goyal
History helps us to become better students, judge wisely, understand change, and most importantly, it tells us who we are. It helps us to understand what happened, why it happened and what its ramifications are. Winston Churchill once said: "Study history, study history. In history lie all the secrets of statecraft." Here, we take this opportunity to pay our gratitude to our esteemed teachers who worked relentlessly for uplifting of the department of Neurology, PGIMER, Chandigarh; and, narrate chronicles of all those people who made this department reach the heights where it stands today...
January 2018: Neurology India
Tarun Narang, Rahul Mahajan, Sunil Dogra
No abstract text is available yet for this article.
November 2017: Indian Dermatology Online Journal
Tulika Singh, Niranjan Khandelwal, Veenu Singla, Dileep Kumar, Madhu Gupta, Gurpreet Singh, Amanjit Bal
Mammography is the only method presently considered appropriate for mass screening of breast cancer. However, higher breast density was strongly associated with lower mammographic sensitivity. Breast density is also identified as independent and strongest risk factors for breast cancer. Studies have shown women with high breast density have four to six times increased risk of breast cancer as compare to women with fatty breast. It varies between different age group it generally decreases with increasing age in postmenopausal women and it can be different in different ethnic groups and people from different geographical areas...
November 15, 2017: Breast Journal
Ashish Bhalla, Ashok Kumar Pannu, Vikas Suri
BACKGROUND: The aim of this study was to evaluate the etiology of hemoptysis in patients presenting to emergency department of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. METHOD: Prospectively 110 patients presenting to the emergency department with history of hemoptysis were screened for a period of one and half years. Out of these, 64 patients having true hemoptysis were enrolled in the study. The patients were clinically evaluated with detailed history...
July 2017: International Journal of Mycobacteriology
Parul Chawla Gupta, Mona Duggal, Limalemla Jamir, Drishti Sharma, Ankita Kankaria, Shreyaswi Sathyanath, Rupinder Kaur, Kirtan Rana, Jagat Ram
PURPOSE: To assess the knowledge and attitude of school-going adolescents regarding corneal donation in government and private schools in an urban area of Northern India. METHODS: A school-based cross-sectional study was conducted in an urban field practice area of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. A total of 365 participants of the seventh to 10th grade were enrolled from a government school and a private school...
May 2017: Cornea
Nishant Jain, Vinod Kumar
In this paper, region-difference filters for the segmentation of liver ultrasound (US) images are proposed. Region-difference filters evaluate maximum difference of the average of two regions of the window around the center pixel. Implementing the filters on the whole image gives region-difference image. This image is then converted into binary image and morphologically operated for segmenting the desired lesion from the ultrasound image. The proposed method is compared with the maximum a posteriori-Markov random field (MAP-MRF), Chan-Vese active contour method (CV-ACM), and active contour region-scalable fitting energy (RSFE) methods...
June 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Sunita Saini, Sukhpal Kaur, Karobi Das, Vikas Saini
CONTEXT: Using the first drop or second drop of blood while measuring blood glucose (BG) values. OBJECTIVE: The study was planned to compare the BG values from the first and second drops of blood. RESEARCH SETTINGS: The study was conducted at the Main Intensive Care Unit, PGIMER, Chandigarh, India. RESEARCH DESIGN: This study was a comparative study. MATERIALS AND METHODS: Ninety patients aged 2-93 years were enrolled in this study...
November 2016: Indian Journal of Critical Care Medicine
Harvinder Kaur, Anil Kumar Bhalla, Praveen Kumar
Background: Available information on auxological attainments of symmetric and asymmetric SGA (small for gestational age) infants presents conflicting views. The complete absence of longitudinal data on growth patterns of both types of Indian SGA infants prompted us to undertake this study. Aim: To study distance and velocity growth pattern of weight and crown-heel length (CHL) of symmetric and asymmetric SGA infants. Subjects & Methods: Weight and CHL amongst full-term 100 symmetric SGA, 100 asymmetric SGA and 100 AGA infants from upper socio-economic strata were mixed-longitudinally measured at birth, 1, 3, 6, 9 and 12 months in the Department of Pediatrics, PGIMER, Chandigarh, India...
April 1, 2017: Anthropologischer Anzeiger; Bericht ├╝ber die Biologisch-anthropologische Literatur
Jasbir Arora, Indu Talwar, Daisy Sahni, Vidya Rattan
BACKGROUND: Dentine has been examined extensively for age-related physiological changes, but there are limited data on age-related changes at ultrastructural level of dentine. AIM: The present study aimed to examine age-related ultrastructural changes in calcospherites of human dentine under the scanning electron microscope. MATERIALS AND METHODS: Thirty single rooted teeth of North Western adult Indians (18-75 years) were collected from the Department of Oral Health Sciences, PGIMER, Chandigarh...
June 2017: Annals of Human Biology
Rajesh Kumar, Radhika Srinivasan, Nalini Gupta, Pranab Dey, Arvind Rajwanshi, Raje Nijhawan, Anupam Lal, Naveen Kalra
BACKGROUND: Ultrasound-guided fine-needle aspiration cytology (FNAC) is the standard modality for diagnosis of gallbladder malignant neoplasms. Adenocarcinoma is the most common malignancy; however, other types may also be encountered. The aim of this study was to perform a retrospective analysis of gallbladder malignancies diagnosed on FNAC in the last 5 years to document the cytomorphological spectrum and the variations thereof. METHODS: The records of the Department of Cytology, PGIMER were searched from July 2010 to June 2015 and all cases of gallbladder malignancies were analyzed in detail for cytomorphological characteristics...
January 2017: Diagnostic Cytopathology
Vishal Kumar, Amarjeet Singh, Manoj K Tewari, Sukhpal Kaur
PROBLEM STATEMENT: Neurosurgical patients require special care not only in the hospital but also after their discharge from the hospital. Comprehension and compliance to the instructions given by the doctors/nurses at the time of discharge is important in home care of these patients. Many such patients suffer from various co-morbidities. Variable periods of convalescence affect health-related quality of life in these patients. PURPOSE OF THE STUDY: To determine the degree of compliance of neurosurgery patients and their family caregivers with the discharge advice given by the consultantsTo evaluate the quality of life of these patientsTo know the problems faced by these patients at home...
October 2016: Asian Journal of Neurosurgery
Ashish Jain, Ajju Agnihotri, Neelam Marwaha, Ratti Ram Sharma
INTRODUCTION: Red cell allo- and auto-immunization is a well recognized problem in multi-transfused thalassemic patients. We conducted this study on 301 multi-transfused thalassemic patients under the Thalassemia Transfusion Programme of Advanced Pediatric Centre of PGIMER. AIMS AND OBJECTIVES: The study was designed to determine the frequency of alloimmunization and autoimmunization in multi-transfused thalassemic patients and to establish the specificity of alloantibody to red cell antigens, if alloimmunization is detected...
July 2016: Asian Journal of Transfusion Science
Ashirwad Karigoudar, Arun Kumar Gupta, Sourabh Mukharjee, Nikhil Gupta, C K Durga
The aim of this study is to assess the advantages of fibrin glue over Prolene suture in fixation of the mesh in open inguinal hernia repair. Sixty-four cases of inguinal hernia underwent hernia repair by the Lichtenstein method in the department of surgery in PGIMER & Dr. RML Hospital, New Delhi. The patients were randomized prospectively into group A (fibrin glue group) and group B (Prolene suture group). In group A, fibrin glue was used for mesh fixation, and in group B, Prolene suture was used for mesh fixation...
August 2016: Indian Journal of Surgery
R John, M S Dhillon, K Syam, S Prabhakar, P Behera, H Singh
BACKGROUND: Sports-related knee injuries occur commonly in athletes. However, there is no published epidemiological study from India till date. OBJECTIVES: The purpose of this study was to identify common injuries sustained by Indian athletes participating in different sports and to study various associated demographic features. A secondary objective was to investigate different factors, which may affect return to sport by the athlete. STUDY DESIGN: Cross-sectional study (observational study)...
July 2016: Journal of Clinical Orthopaedics and Trauma
A Rajwanshi, M Rohilla, P Singh
OBJECTIVE: Fine needle aspiration (FNA) cytology is a relatively non-invasive method for diagnosing both superficial and deep-seated neoplastic and non-neoplastic lesions. In this study, we evaluated the diagnostic utility of trans-oral FNA in cervical (C1 and C2) vertebral and paravertebral lesions. MATERIAL AND METHODS: Eighteen FNA cases of cervical vertebral and paravertebral lesions performed by a trans-oral route without any image-guidance between 1995 and 2014 were retrieved from the archives of the cytology department at PGIMER, Chandigarh and reviewed...
February 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
Manupriya Sharma, Man Updesh Singh Sachdeva, Neelam Varma, Subhash Varma, R K Marwaha
BACKGROUND: Identification of aberrant antigen expression is important in characterizing neoplastic population among non.neoplastic bone marrow counterparts and further in the detection of minimal residual disease. (MRD). Flow cytometry (FCM) is an important tool in identifying aberrant phenotypes. Incidence of aberrant phenotypes varies considerably in independent studies and its association with prognostic factors is still debatable. AIM: To identify the prevalence of aberrant phenotypes on immunophenotyping in a large series of de novo acute lymphoblastic leukemia (ALL) and to evaluate any association with initial clinical and hematological features...
April 2016: Journal of Cancer Research and Therapeutics
Deepti Suri, Avinash Sharma, Sagar Bhattad, Amit Rawat, Sunil Arora, Ranjana W Minz, Surjit Singh
AIM: Children with human immunodeficiency virus (HIV) infection usually present with recurrent and unusual infections. Although reported among adults, arthritis as a predominant presentation in children with HIV is rare. Reactive arthritis is considered to be the most common musculoskeletal manifestation in adults with HIV infection. However, in children, septic or HIV-related arthritis has been described. We report four children having arthritis with HIV disease and their long-term outcome; out of which three had human leukocyte antigen (HLA)-B27-related arthritis...
October 2016: International Journal of Rheumatic Diseases
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