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Nishant Jain, Vinod Kumar
In this paper, region-difference filters for the segmentation of liver ultrasound (US) images are proposed. Region-difference filters evaluate maximum difference of the average of two regions of the window around the center pixel. Implementing the filters on the whole image gives region-difference image. This image is then converted into binary image and morphologically operated for segmenting the desired lesion from the ultrasound image. The proposed method is compared with the maximum a posteriori-Markov random field (MAP-MRF), Chan-Vese active contour method (CV-ACM), and active contour region-scalable fitting energy (RSFE) methods...
December 26, 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Sunita Saini, Sukhpal Kaur, Karobi Das, Vikas Saini
CONTEXT: Using the first drop or second drop of blood while measuring blood glucose (BG) values. OBJECTIVE: The study was planned to compare the BG values from the first and second drops of blood. RESEARCH SETTINGS: The study was conducted at the Main Intensive Care Unit, PGIMER, Chandigarh, India. RESEARCH DESIGN: This study was a comparative study. MATERIALS AND METHODS: Ninety patients aged 2-93 years were enrolled in this study...
November 2016: Indian Journal of Critical Care Medicine
Harvinder Kaur, Anil Kumar Bhalla, Praveen Kumar
Background: Available information on auxological attainments of symmetric and asymmetric SGA (small for gestational age) infants presents conflicting views. The complete absence of longitudinal data on growth patterns of both types of Indian SGA infants prompted us to undertake this study. Aim: To study distance and velocity growth pattern of weight and crown-heel length (CHL) of symmetric and asymmetric SGA infants. Subjects & Methods: Weight and CHL amongst full-term 100 symmetric SGA, 100 asymmetric SGA and 100 AGA infants from upper socio-economic strata were mixed-longitudinally measured at birth, 1, 3, 6, 9 and 12 months in the Department of Pediatrics, PGIMER, Chandigarh, India...
November 23, 2016: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
Jasbir Arora, Indu Talwar, Daisy Sahni, Vidya Rattan
BACKGROUND: Dentine has been examined extensively for age-related physiological changes but there exists limited data on age related changes at ultrastructural level of dentine Aim: The present study aimed to examine age related ultrastructural changes in calcospherites of human dentine under the scanning electron microscope. MATERIAL AND METHODS: 30 single rooted teeth of North Western adult Indians (18-75 yrs) were collected from the Department of Oral Health Sciences, PGIMER, Chandigarh...
December 8, 2016: Annals of Human Biology
Rajesh Kumar, Radhika Srinivasan, Nalini Gupta, Pranab Dey, Arvind Rajwanshi, Raje Nijhawan, Anupam Lal, Naveen Kalra
BACKGROUND: Ultrasound-guided fine-needle aspiration cytology (FNAC) is the standard modality for diagnosis of gallbladder malignant neoplasms. Adenocarcinoma is the most common malignancy; however, other types may also be encountered. The aim of this study was to perform a retrospective analysis of gallbladder malignancies diagnosed on FNAC in the last 5 years to document the cytomorphological spectrum and the variations thereof. METHODS: The records of the Department of Cytology, PGIMER were searched from July 2010 to June 2015 and all cases of gallbladder malignancies were analyzed in detail for cytomorphological characteristics...
January 2017: Diagnostic Cytopathology
Vishal Kumar, Amarjeet Singh, Manoj K Tewari, Sukhpal Kaur
PROBLEM STATEMENT: Neurosurgical patients require special care not only in the hospital but also after their discharge from the hospital. Comprehension and compliance to the instructions given by the doctors/nurses at the time of discharge is important in home care of these patients. Many such patients suffer from various co-morbidities. Variable periods of convalescence affect health-related quality of life in these patients. PURPOSE OF THE STUDY: To determine the degree of compliance of neurosurgery patients and their family caregivers with the discharge advice given by the consultantsTo evaluate the quality of life of these patientsTo know the problems faced by these patients at home...
October 2016: Asian Journal of Neurosurgery
Ashish Jain, Ajju Agnihotri, Neelam Marwaha, Ratti Ram Sharma
INTRODUCTION: Red cell allo- and auto-immunization is a well recognized problem in multi-transfused thalassemic patients. We conducted this study on 301 multi-transfused thalassemic patients under the Thalassemia Transfusion Programme of Advanced Pediatric Centre of PGIMER. AIMS AND OBJECTIVES: The study was designed to determine the frequency of alloimmunization and autoimmunization in multi-transfused thalassemic patients and to establish the specificity of alloantibody to red cell antigens, if alloimmunization is detected...
July 2016: Asian Journal of Transfusion Science
Ashirwad Karigoudar, Arun Kumar Gupta, Sourabh Mukharjee, Nikhil Gupta, C K Durga
The aim of this study is to assess the advantages of fibrin glue over Prolene suture in fixation of the mesh in open inguinal hernia repair. Sixty-four cases of inguinal hernia underwent hernia repair by the Lichtenstein method in the department of surgery in PGIMER & Dr. RML Hospital, New Delhi. The patients were randomized prospectively into group A (fibrin glue group) and group B (Prolene suture group). In group A, fibrin glue was used for mesh fixation, and in group B, Prolene suture was used for mesh fixation...
August 2016: Indian Journal of Surgery
R John, M S Dhillon, K Syam, S Prabhakar, P Behera, H Singh
BACKGROUND: Sports-related knee injuries occur commonly in athletes. However, there is no published epidemiological study from India till date. OBJECTIVES: The purpose of this study was to identify common injuries sustained by Indian athletes participating in different sports and to study various associated demographic features. A secondary objective was to investigate different factors, which may affect return to sport by the athlete. STUDY DESIGN: Cross-sectional study (observational study)...
July 2016: Journal of Clinical Orthopaedics and Trauma
A Rajwanshi, M Rohilla, P Singh
OBJECTIVE: Fine needle aspiration (FNA) cytology is a relatively non-invasive method for diagnosing both superficial and deep-seated neoplastic and non-neoplastic lesions. In this study, we evaluated the diagnostic utility of trans-oral FNA in cervical (C1 and C2) vertebral and paravertebral lesions. MATERIAL AND METHODS: Eighteen FNA cases of cervical vertebral and paravertebral lesions performed by a trans-oral route without any image-guidance between 1995 and 2014 were retrieved from the archives of the cytology department at PGIMER, Chandigarh and reviewed...
August 3, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
Manupriya Sharma, Man Updesh Singh Sachdeva, Neelam Varma, Subhash Varma, R K Marwaha
BACKGROUND: Identification of aberrant antigen expression is important in characterizing neoplastic population among non.neoplastic bone marrow counterparts and further in the detection of minimal residual disease. (MRD). Flow cytometry (FCM) is an important tool in identifying aberrant phenotypes. Incidence of aberrant phenotypes varies considerably in independent studies and its association with prognostic factors is still debatable. AIM: To identify the prevalence of aberrant phenotypes on immunophenotyping in a large series of de novo acute lymphoblastic leukemia (ALL) and to evaluate any association with initial clinical and hematological features...
April 2016: Journal of Cancer Research and Therapeutics
Deepti Suri, Avinash Sharma, Sagar Bhattad, Amit Rawat, Sunil Arora, Ranjana W Minz, Surjit Singh
AIM: Children with human immunodeficiency virus (HIV) infection usually present with recurrent and unusual infections. Although reported among adults, arthritis as a predominant presentation in children with HIV is rare. Reactive arthritis is considered to be the most common musculoskeletal manifestation in adults with HIV infection. However, in children, septic or HIV-related arthritis has been described. We report four children having arthritis with HIV disease and their long-term outcome; out of which three had human leukocyte antigen (HLA)-B27-related arthritis...
October 2016: International Journal of Rheumatic Diseases
Devki Nandan, Prachi Kansal, Neha Patharia, Parul Goyal
PURPOSE: The objective of this study is to measure levels of nitrites in induced sputum in children with asthma and correlate it with clinical asthma parameters. METHOD: This prospective observational study was done in PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, on 91 children aged 7-18 years with mild and moderate persistent asthma. Patients were specifically evaluated for five clinical parameters of asthma (i.e. Days of acute exacerbations, use of salbutamol as rescue medication, emergency visits, nights with cough, days of school absence) and induced sputum nitrite levels was done at the time of enrollment and 3 months after treatment with inhaled budesonide...
July 2016: Journal of Laboratory Physicians
Shashwat Sarin, Lileswar Kaman, Divya Dahiya, Arunanshu Behera, Bikash Medhi, Yogesh Chawla
UNLABELLED: During major liver resection, ischemia reperfusion injury occurs resulting in adverse outcome. Animal studies have demonstrated the beneficial effect of statins on hepatic ischemic injury, but no clinical studies have been performed. Twenty consecutive patients undergoing major hepatic resection were included and were randomized into two groups. The study group (n = 10) patients received oral atorvastatin 40 mg for 3 days prior to surgery, including the day of surgery, and the control group (n = 10) received a placebo...
June 2016: Updates in Surgery
Geeti Khullar, Uma Nahar Saikia, Dipankar De, Sanjeev Handa, Bishan Das Radotra
BACKGROUND: Squamous and basal cell carcinomas together constitute the majority of non-melanoma skin cancers. These malignancies are infrequent in Indians as compared to the white skinned population. Literature on squamous cell carcinoma in dark skin is limited. AIM: To analyze the risk factors and to characterize the histopathological subtypes of cutaneous squamous cell carcinoma in Indian patients in an area, non-endemic for arsenicosis. METHODS: A retrospective analysis of data from January 2003 to August 2013 was performed to evaluate the predisposing factors and histopathological types of cutaneous squamous cell carcinoma at the Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh...
May 2016: Indian Journal of Dermatology, Venereology and Leprology
Vishal Jogi, Sahil Mehta, Amod Gupta, Paramjeet Singh, Vivek Lal
CONTEXT: Retinal migraine (RM) is considered as one of the rare causes of transient monocular visual loss (TMVL) and has not been studied in Indian population. OBJECTIVES: The study aims to analyze the clinical and investigational profile of patients with RM. MATERIALS AND METHODS: This is an observational prospective analysis of 12 cases of TMVL fulfilling the International Classification of Headache Disorders-2nd edition (ICHD-II) criteria of RM examined in Neurology and Ophthalmology Outpatient Department (OPD) of Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh from July 2011 to October 2012...
January 2016: Annals of Indian Academy of Neurology
Subhash Soni, Peush Sahni, Samiran Nundy
s presented at scientific meetings are important for making ongoing research more widely known and may also reflect the quality of the parent institution's standard of patient care. We analyzed the abstracts presented at the annual meetings of IASG for the past 5 years for (i) medium of presentation (oral/poster/videos), (ii) subjects discussed, (iii) institution of origin, (iv) whether a prospective/ retrospective study or a case report, (v) changing trends, and (vi) awards received. Of the 1340 abstracts analyzed, there were 18...
December 2015: Indian Journal of Surgery
Mahendra Kumar, Man Updesh Singh Sachdeva, Shano Naseem, Jasmina Ahluwalia, Reena Das, Neelam Varma, R K Marwaha
BACKGROUND: Langerhans' cell histiocytosis (LCH) is a reactive proliferative disease of unknown pathogenesis characterized by proliferation of Langerhans cells. Involvement of bone marrow (BM), liver and lung are related to high risk factors and poor survival. The aim of this report is to highlight the clinical and haematological findings of 5 cases of LCH with BM infiltration which may help to predict involvement of BM. CASE SERIES: Five cases of Langerhan's cell histiocytosis with bone marrow infiltration were retrieved from archives of Department of Hematology, PGIMER and Chandigarh for review and further analysis...
October 1, 2015: International Journal of Hematology-oncology and Stem Cell Research
Vinay Rathore, Arun Bansal, Sunit C Singhi, Pratibha Singhi, Jayashree Muralidharan
BACKGROUND: Data on outcome of children undergoing in-hospital cardiopulmonary resuscitation (CPR) in low- and middle-income countries are scarce. AIMS: To describe the clinical profile and outcome of children undergoing in-hospital CPR. METHODS: This prospective observational study was undertaken in the Advanced Pediatric Center, PGIMER, Chandigarh. All patients aged 1 month to 12 years who underwent in-hospital CPR between July 2010 and March 2011 were included...
February 3, 2016: Paediatrics and International Child Health
Ravi Kumar H S, Vijay G Goni, Batra Y K
STUDY DESIGN: The study was conducted on patients who received autologous conditioned serum (ACS) as a line of treatment at the Orthopedics outpatient department of Post Graduate Institute of Medical Education and Research (PGIMER, Chandigarh) from January 2011 to June 2012. Of the 1,224 patients, 20 males or females were included in the study based on the inclusion and exclusion criteria. The institutional board of PGIMER approved the study before it was initiated. PURPOSE: To study the efficacy of ACS in the treatment of unilateral lumbar radiculopathy...
December 2015: Asian Spine Journal
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