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https://www.readbyqxmd.com/read/28070050/-clinical-comparative-analysis-for-pulmonary-histoplasmosis-and-progressive-disseminated-histoplasmosis
#1
Yan Zhang, Xiaoli Su, Yuanyuan Li, Ruoxi He, Chengping Hu, Pinhua Pan
To compare clinical features, diagnosis and therapeutic effect between pulmonary histoplasmosis and progressive disseminated histoplasmosis.
 Methods: A retrospective analysis for 12 cases of hospitalized patients with histoplasmosis, who was admitted in Xiangya Hospital, Central South University during the time from February 2009 to October 2015, was carried out. Four cases of pulmonary histoplasmosis and 8 cases of progressive disseminated histoplasmosis were included. The differences of clinical features, imaging tests, means for diagnosis and prognosis were analyzed between the two types of histoplasmosis...
December 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28043607/what-is-in-a-cough
#2
Kevin P Fennelly
OBJECTIVE/BACKGROUND: The aims of this talk are to: (a) provide an overview of our method of collecting, quantifying, and sizing infectious aerosols of Mycobacterium tuberculosis; and (b) to review data indicating that cough aerosol cultures of M. tuberculosis are the best predictors of infection and incident disease among household contacts of persons with active tuberculosis (TB). New infection was defined as tuberculin skin test conversion. METHODS: We developed a cough aerosol sampling system by placing two Andersen cascade impactor viability samplers inside a cylinder into which patients cough via connector tubing...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043585/occurrence-of-zoonotic-tuberculosis-in-occupationally-exposed-high-risk-groups-in-peshawar-pakistan
#3
Irfan Khattak, Muhammad H Mushtaq, Sultan Ayaz, Mansur U D Ahmad, Sadeeq U Rahman
OBJECTIVE/BACKGROUND: To determine the occurrence of active pulmonary tuberculosis (TB) due to Mycobacterium bovis in abattoir workers, butchers, livestock farmers, and veterinarians and to document their knowledge and practices regarding bovine TB (bTB). METHODS: A cross-sectional study was conducted among abattoir workers, butchers, livestock farmers, veterinary doctors, and veterinary assistants. Sputum samples were collected from the respondents with a chronic cough and data on sociodemographic conditions, knowledge, and practices regarding TB were obtained...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043535/delay-in-diagnosis-among-pulmonary-tuberculosis-patients-of-rayagada-district-odisha-india
#4
Dasarathi Das, Bhagirathi Dwibedi
BACKGROUND: India accounts for more than one-fifth of the world's tuberculosis (TB) burden. In spite of efforts taken by the Revised National Tuberculosis Control Programme, tribal areas of the state of Odisha report a high TB incidence over the years. One of the reasons could be delay in reporting to health facilities by the symptomatic patients. During such delays an active case may infect numerous susceptible people thereby contributing to the perpetuation of the infection. The delay in diagnosis may be as long as 2-3months and even more in hard-to-reach areas...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043486/tuberculosis-in-children
#5
Ali Akbar Velayati
Tuberculosis (TB) is the main cause of infection-related death in the world. Children make up ∼5-15% of all TB cases. Severe forms of disease such as meningitis and disseminated form are more common in children. Due to current estimates of World Health Organization (WHO) in 2015, one million children suffer from TB around the world; of these, it is estimated that more than 136,000 die a year. One study estimated 67million children with latent TB which develops to active form with the rate of ∼850,000 each year...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28029320/pulmonary-infiltrates-in-a-patient-with-advanced-melanoma
#6
Charles A Powell
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
December 28, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28011973/pulmonary-and-vertebral-mycobacterium-avium-disease-in-a-hiv-negative-71-year-old-man-a-case-report
#7
Mihailo I Stjepanovic, Dragica P Pesut, Aleksandar R Lesic, Ruza S Stevic
Nontuberculous mycobacteria (NTM) caused pulmonary disease is on increase worldwide, especially in countries with decreasing time trend of tuberculosis incidence. NTM skeletal affection is rare. Mycobacterium avium related disease, with still unclear clinical and radiologic features, is in current focus of both clinicians and researchers. An exhausted severely ill 71-year-old man was admitted on emergency due to cough, dyspnea and lumbar back pain to be diagnosed with terminal phase M. avium disease. Three sputum smears were positive for acid fast bacilli and M...
1, 2016: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/28011971/tuberculous-pericarditis-a-case-report
#8
Affan Denk, Mehmet Ali Kobat, Safak Ozer Balin, Sumeyye Selim Kara, Orhan Dogdu
Pericardial effusion is common disease and difficult to diagnose. Tuberculosis accounts for up to 4% of acute pericarditis and 7% of cardiac tamponade cases. Quick treatment can be lifesaving but requires accurate diagnosis. We report a case of a 65-year-old man who presented with a 3-week history of fever with chills, non-productive cough and dyspnea. The case was diagnosed by positivity of acid-fast staining, culture and polymerase chain reaction (PCR) of the aspirated pericardial fluid and treated promptly with antituberculosis drugs...
1, 2016: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/28011331/multi-drug-resistant-female-genital-tuberculosis-a-preliminary-report
#9
J B Sharma, Alka Kriplani, Eshani Sharma, Sangeeta Sharma, Sona Dharmendra, Sunesh Kumar, P Vanamail, S K Sharma
OBJECTIVE: Evaluation of 6 patients presenting with tubo-ovarian mass or infertility with multi drug resistant (MDR) female genital tuberculosis (FGTB). STUDY DESIGN: It was an observational study in a tertiary referral centre, India on subjects with MDR FGTB on clinical examination and investigations. All patients were given category IV drugs using kanamycin (intramuscular), levofloxacin, pyrazinamide, cycloserine, ethionamide and ethambutol (or para aminosalicylic acid [PAS] for ethambutol resistant cases) for 6 months intensive phase followed by oral levofloxacin, cycloserine, ethionamide and ethambutol (or PAS for ethambutol resistant cases) for 18 months continuation phase...
December 12, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27965902/tuberculosis-and-migration-a-challenge-for-medical-staff-and-public-health
#10
Ines Griesshammer, David Shiva Srivastava, Christophe von Garnier, Till Silvan Blaser, Aris Exadaktylos, Moritz Steib
A high number of asylum seekers enter Switzerland every year. They often originate from countries with a high TB prevalence. Our patient from Somalia presented with 2 lipoma-like tumors with pain on palpation on his left chest wall but no symptoms including coughing, fever, night-sweats, or loss of weight. CT scan then showed diffuse infiltrations of his lung and multiple abscesses on his left chest wall. Therefore contagious tuberculosis (TB) was suspected and the patient was put in isolation. In the follow-up the diagnosis of open TB was proofed with bronchial secretion and EBUS-guided biopsy that showed acid-fast rods...
2016: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/27955709/the-characteristics-of-patients-with-mycobacterium-tuberculosis-blood-stream-infections-in-beijing-china-a-retrospective-study
#11
Xiaoqing Liu, Sainan Bian, Yueqiu Zhang, Lifan Zhang, Qiwen Yang, Peng Wang, Yingchun Xu, Xiaochun Shi, Yao Zhang, Roy F Chemaly
BACKGROUND: Published information regarding the clinical characteristics, laboratory findings, and outcomes of patients with Mycobacterium tuberculosis (MTB) blood stream infection (BSI) is limited. We aimed in this study to evaluate the clinical characteristics, laboratory evaluation, and outcomes of patients with MTB BSI. METHODS: All patients diagnosed with MTB BSI at Peking Union Medical College Hospital between January 2008 and May 2014 were identified by examining the electronic database listing results of all blood cultures...
December 12, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27942386/are-patients-with-pulmonary-tuberculosis-who-are-identified-through-active-case-finding-in-the-community-different-than-those-identified-in-healthcare-facilities
#12
S T Abdurrahman, L Lawson, M Blakiston, J Obasanya, M A Yassin, R M Anderson, O Oladimeji, A Ramsay, L E Cuevas
The lack of healthcare access contributes to large numbers of tuberculosis (TB) cases being missed and has led to renewed interest in outreach approaches to increase detection. It is however unclear whether outreach activities increase case detection or merely identify patients before they attend health facilities. We compared adults with cough of >2 weeks' duration recruited in health facilities (1202 participants) or in urban slums (2828 participants) in Nigeria. Participants provided demographic and clinical information and were screened using smear microscopy...
January 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/27922582/-knowledge-and-perception-about-tuberculosis-among-public-transport-workers-in-lima-peru
#13
Danitza Lukac, Octavio Garaycochea, Alvaro Taype-Rondan, Laura Luque Bustamante, André Mujica-Vasquez, Dario Zamora
OBJECTIVES: To describe the level of knowledge and perception of tuberculosis among public transport workers attending Road Safety Education courses in Lima, Peru. METHODS: An observational, cross-sectional, analytic study was conducted between July and August 2014 in public transport workers attending the courses of Road Safety education. In Lima, such courses are mandatory for workers in the public transport area. An anonymous and voluntary survey was applied to obtain the following variables: sociodemographic characteristics, history of tuberculosis, tuberculosis knowledge and attitudes towards the disease...
November 23, 2016: Medwave
https://www.readbyqxmd.com/read/27900225/internal-jugular-vein-thrombosis-in-isolated-tuberculous-cervical-lymphadenopathy
#14
Sanjay Khaladkar, Avadhesh Chauhan, Arijit Ghosh, Kunaal Jain, Surbhi Chauhan
Tuberculosis is a common infectious disease with a high prevalence in developing countries and presents a major public health issue. Internal jugular vein (IJV) thrombosis is a rare complication in tuberculous cervical lymphadenopathy. We report a case of 26-year male patient with a history of low-grade evening rise in fever, dry cough, loss of appetite, and loss of weight with swelling in lower neck on right side. Ultrasonography (USG) neck showed well-defined hypoechoic lymph nodes posterior to right IJV and common carotid artery in the lower neck at level IV and in the right supraclavicular region showing central necrotic areas with adjoining IJV thrombosis...
2016: Case Reports in Radiology
https://www.readbyqxmd.com/read/27899384/rifampicin-induced-adrenal-crisis-in-a-patient-with-tuberculosis-a-therapeutic-challenge
#15
Nicholas Denny, Sarika Raghunath, Praveen Bhatia, Muntasir Abdelaziz
A 55-year-old Indian man presented with productive cough and a large left pleural effusion. Pleural fluid culture grew Mycobacterium tuberculosis, and he was started on antituberculosis therapy. One week later, the patient presented to hospital with drowsiness, dehydration and hypotension. He was transferred to critical care and only improved after starting hydrocortisone and stopping rifampicin. His short synACTHen test subsequently confirmed primary adrenal insufficiency, and a CT of the abdomen showed bilateral adrenal enlargement...
November 29, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27882294/cough-and-fever-in-an-immigrant-adolescent-with-abnormal-chest-x-ray
#16
Nicole Giles, Rajeev Bhatia
Tuberculosis (TB) remains a leading cause of death from infectious disease worldwide with 80,000 pediatric deaths annually. Disease caused by Mycobacterium tuberculosis (Mtb) is usually asymptomatic in pediatric patients and resolves after completion of standard therapy with isoniazid (INH). Rare reports document children greater than 10 years of age in endemic regions developing adult type cavitary disease, an infectious pulmonary tuberculosis lesion. This is a notable case of post-infectious pulmonary TB disease with adult type cavitation in an immigrant adolescent, which developed even after completing standard therapy with INH...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27879464/severe-pleuropulmonary-paragonimiasis-caused-by-paragonimus-mexicanus-treated-as-tuberculosis-in-ecuador
#17
Manuel Calvopina, Daniel Romero-Alvarez, Rubén Macias, Hiromu Sugiyama
A 30-year-old male, from a subtropical region of Ecuador, was hospitalized with a 5-year history of persistent cough with rusty brown sputum, chest pain, and progressive dyspnea. The patient underwent thoracic surgery 3 years ago for pleural effusion and subsequently received a 9-month regimen treatment of tuberculosis. However, there was no clinical resolution and symptoms became progressively worse. A chest radiograph and computerized tomography scan showed several small nodules in both lungs. Eggs of Paragonimus spp...
November 22, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27872739/30-years-retrospective-review-of-tuberculosis-cases-in-a-tuberculosis-dispensary-in-bursa-nilufer-turkey-1985-2014-changes-of-epidemics
#18
Kayıhan Pala, Harika Gerçek, Tuncay Aydin Taş, Rukiye Çakir, Sedef Özgüç, Timur Yildiz
OBJECTIVE: The aim of this study is to describe the epidemiological and clinical aspects of patients who applied to the Bursa Nilufer Tuberculosis Dispensary by investigating the trends in epidemics over three decades. METHOD: In this retrospective observational study, the records of all tuberculosis cases (1630 patients) treated in the last 30 years (1985-2014) at the Bursa Nilufer Tuberculosis Dispensary were examined and statistically analyzed. RESULTS: Males comprised 65...
2016: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/27867459/successful-treatment-of-giant-left-subclavian-artery-pseudoaneurysm-abutting-the-arch-of-the-aorta-and-descending-aorta
#19
Hamza Abdur Rahim Khan, Sehrish Batool, Fazal Wahab Khan, Saulat Hasnain Fatimi
A 28-year-old woman presented with 3-month history of fever of unknown origin and progressively increasing cough. She was diagnosed with pulmonary tuberculosis on bronchial lavage cultures. A chest X-ray performed on follow-up showed a new opacity in the left apical area of the chest. Computed tomography scan of chest showed a large 10 cm pseudoaneurysm of the left subclavian artery 1 cm from its take off from the arch of the aorta. The pseudoaneurysm was approached through a left posterolateral thoracotomy and opened following a proximal and distal control...
July 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27866367/risk-for-latent-and-active-tuberculosis-in-germany
#20
Christian Herzmann, Giovanni Sotgiu, Oswald Bellinger, Roland Diel, Silke Gerdes, Udo Goetsch, Helga Heykes-Uden, Tom Schaberg, Christoph Lange
PURPOSE: Few individuals that are latently infected with M. tuberculosis latent tuberculosis infection(LTBI) progress to active disease. We investigated risk factors for LTBI and active pulmonary tuberculosis (PTB) in Germany. METHODS: Healthy household contacts (HHCs), health care workers (HCWs) exposed to M. tuberculosis and PTB patients were recruited at 18 German centres. Interferon-γ release assay (IGRA) testing was performed. LTBI risk factors were evaluated by comparing IGRA-positive with IGRA-negative contacts...
November 19, 2016: Infection
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