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https://www.readbyqxmd.com/read/29344622/barriers-to-and-facilitators-of-implementing-enhanced-recovery-pathways-using-an-implementation-framework-a-systematic-review
#1
Alexander B Stone, Christina T Yuan, Michael A Rosen, Michael C Grant, Lauren E Benishek, Elizabeth Hanahan, Lisa H Lubomski, Clifford Ko, Elizabeth C Wick
Importance: Enhanced recovery pathways (ERPs) have the potential to reduce length of hospital stay, costs, and complications following surgery but can be challenging to implement. Objective: To examine the body of literature on ERPs to assess how authors describe barriers and facilitators of ERP implementation and identify, in aggregate, the best practices that should be considered utilizing the Consolidated Framework for Implementation Research (CFIR) to extract these elements and summarize common barriers and facilitators according to its 5 major domains: (1) intervention characteristics, (2) inner setting, (3) outer setting, (4) characteristics of the individuals, and (5) the process of implementation...
January 17, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29343279/spatial-distribution-and-habitat-characterization-of-mosquito-species-during-the-dry-season-along-the-mara-river-and-its-tributaries-in-kenya-and-tanzania
#2
Gabriel O Dida, Douglas N Anyona, Paul O Abuom, Daniel Akoko, Samson O Adoka, Ally-Said Matano, Philip O Owuor, Collins Ouma
BACKGROUND: Vector-borne diseases are increasingly becoming a major health problem among communities living along the major rivers of Africa. Although larger water bodies such as lakes and dams have been extensively researched, rivers and their tributaries have largely been ignored. This study sought to establish the spatial distribution of mosquito species during the dry season and further characterize their habitats along the Mara River and its tributaries. METHODS: In this cross-sectional survey, mosquito larvae were sampled along the Mara River, its two perennial tributaries (Amala and Nyangores), drying streams, and adjacent aquatic habitats (e...
January 18, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29343110/can-the-physical-environment-itself-influence-neurological-patient-activity
#3
Michelle M Shannon, Marie Elf, Leonid Churilov, John Olver, Alan Pert, Julie Bernhardt
PURPOSE: To evaluate if a changed physical environment following redesign of a hospital ward influenced neurological patient physical and social activity. METHODS: A "before and after" observational design was used that included 17 acute neurological patients pre-move (median age 77 (IQR 69-85) years Ward A and 20 post-move (median age 70 (IQR 57-81) years Ward B. Observations occurred for 1 day from 08.00-17.00 using Behavioral Mapping of patient physical and social activity, and location of that activity...
January 17, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29339060/quantification-of-a-recombinant-antigen-in-an-immuno-stimulatory-whole-yeast-cell-based-therapeutic-vaccine
#4
Jenny Wang, Daniel Stenzel, Ally Liu, Dengfeng Liu, Darren Brown, Alexandre Ambrogelly
Therapeutic vaccines represent an emerging class of immune-modulatory treatments for cancer, infections, and chronic diseases. One such vaccine was designed as an immune stimulator of the T cell response against HBV antigens to eliminate HBV infected cells and offer a therapeutic avenue to treat patients suffering from chronic hepatitis B infection. Whole deactivated Saccharomyces cerevisiae cells expressing a recombinant fusion of HBV X, S and Core antigens elicit T cell responses in mice and activate human T cells linked with viral clearance...
January 12, 2018: Analytical Biochemistry
https://www.readbyqxmd.com/read/29336972/general-anesthesia-for-transcatheter-aortic-valve-replacement-total-intravenous-anesthesia-is-associated-with-less-delirium-as-compared-to-volatile-agent-technique
#5
Allie E Goins, Alan Smeltz, Cassandra Ramm, Paula D Strassle, Emily G Teeter, John P Vavalle, Lavinia Kolarczyk
OBJECTIVE: Investigate the effect of volatile anesthesia versus total intravenous anesthesia on the incidence of postoperative delirium and length of stay in patients undergoing transcatheter aortic valve replacement under general anesthesia. DESIGN: Retrospective study. SETTING: Single institution, academic medical center. PARTICIPANTS: Adult patients who underwent transcatheter aortic valve replacement under general anesthesia between November 2014 and February 2017...
December 11, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29334522/themes-in-literature-related-to-incidence-risk-and-prevention-of-cancer-in-solid-organ-transplantation-recipients-on-immunosuppressive-therapy
#6
Stefanie L Rashti
BACKGROUND: Solid-organ transplants provide a second chance to thousands of critically ill patients with end-organ failure each year. Immunosuppressants are administered to patients to prevent graft rejection of a transplanted organ, such as a heart, kidney, or liver, while placing the recipient at greater risk for infection and cancer. OBJECTIVE: The literature provides evidence of various cancers that have been found to develop in patients' posttransplantation...
January 12, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29334372/pharmacological-blockade-of-asct2-dependent-glutamine-transport-leads-to-antitumor-efficacy-in-preclinical-models
#7
Michael L Schulte, Allie Fu, Ping Zhao, Jun Li, Ling Geng, Shannon T Smith, Jumpei Kondo, Robert J Coffey, Marc O Johnson, Jeffrey C Rathmell, Joe T Sharick, Melissa C Skala, Jarrod A Smith, Jordan Berlin, M Kay Washington, Michael L Nickels, H Charles Manning
The unique metabolic demands of cancer cells underscore potentially fruitful opportunities for drug discovery in the era of precision medicine. However, therapeutic targeting of cancer metabolism has led to surprisingly few new drugs to date. The neutral amino acid glutamine serves as a key intermediate in numerous metabolic processes leveraged by cancer cells, including biosynthesis, cell signaling, and oxidative protection. Herein we report the preclinical development of V-9302, a competitive small molecule antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2...
January 15, 2018: Nature Medicine
https://www.readbyqxmd.com/read/29334149/evidence-based-practice-readiness-a-concept-analysis
#8
Jessica D Schaefer, John M Welton
AIM: To analyse and define the concept "evidence based practice readiness" in nurses. BACKGROUND: Evidence based practice readiness is a term commonly used in health literature, but without a clear understanding of what readiness means. Concept analysis is needed to define the meaning of evidence based practice readiness. METHOD: A concept analysis was conducted using Walker and Avant's method to clarify the defining attributes of evidence based practice readiness as well as antecedents and consequences...
January 15, 2018: Journal of Nursing Management
https://www.readbyqxmd.com/read/29327603/a-qualitative-investigation-into-the-patient-centered-goal-setting-practices-of-allied-health-clinicians-working-in-rehabilitation
#9
Lisa J Cameron, Lisa M Somerville, Catherine E Naismith, Dina Watterson, Valentina Maric, Natasha A Lannin
OBJECTIVE: To explore the ways clinicians engage rehabilitation patients in patient-centered goal setting and identify factors influencing the goal-setting process. DESIGN: Ethnographic study utilizing observed practice-thematic analysis. SETTING: Four rehabilitation wards of a large metropolitan hospital in Melbourne, Australia. SUBJECTS: Participants included 17 rehabilitation patients, 18 allied health clinicians and one family member...
January 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29325943/neurosurgical-care-availability-and-access-in-low-and-middle-income-countries
#10
Maria Punchak, Swagoto Mukhopadhyay, Sonal Sachdev, Ya-Ching Hung, Sophie Peeters, Abbas Rattani, Michael Dewan, Walter D Johnson, Kee B Park
BACKGROUND: An estimated 5 billion people worldwide lack access to basic surgical care. In particular, the vast majority of low- and middle-income countries (LMICs) currently struggle to provide adequate neurosurgical services. Significant barriers exist, including limited access to trained medical, nursing and allied health staff, lack of equipment, and availability of services at reasonable distance and at reasonable cost to patients. An accurate assessment of current neurosurgical capacity in LIMCs is an essential first step in tackling this deficit...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29322855/fatigue-in-pediatric-patients-with-familial-mediterranean-fever
#11
Semanur Özdel, Z Birsin Özçakar, Nilgün Cakar, Fatma Aydın, Elif Çelikel, Atilla H Elhan, Fatoş Yalçınkaya
OBJECTIVES: Familial Mediterranean fever (FMF) is characterized by recurrent, self-limited attacks of fever with serositis involving the peritoneum, pleura and joints. Fatigue is a common problem in many pediatric rheumatic diseases; however, has not been evaluated systematically in FMF patients. Accordingly, the aim of this study was to evaluate fatigue and its possible allied factors in patients with FMF. METHODS: Patients with FMF, aged between 10-18 years, were assessed by completed validated fatigue questionnaire (Checklist Individual Strength-20)...
January 11, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29322683/exploring-the-research-culture-of-nurses-and-allied-health-professionals-ahps-in-a-research-focused-and-a-non-research-focused-healthcare-organisation-in-the-uk
#12
Manju Luckson, Fiona Duncan, Azita Rajai, Carol Haigh
AIMS AND OBJECTIVES: There is a gap in knowledge about the research culture of nurses and Allied Health Professionals (AHPs) in the UK, and the influence of a dedicated research strategy and funding. It is important to understand the culture in order to effectively promote evidence - based patient care. The primary aim of this research was to explore the influence of research focused exposure on the research culture of nurses and AHPs in the UK, and to identify if there was a difference in the research culture between a research- focused and non-research - focused clinical area (City and Riverside Hospitals)...
January 10, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29322576/a-mixed-method-thematic-review-health-related-decision-making-by-the-older-person
#13
REVIEW
Lindy King, Ann Harrington, Ecushla Linedale, Elizabeth Tanner
AIMS: To undertake a mixed method thematic literature review that explored how elderly adults approached decision making in regard to their health care following discharge. BACKGROUND: A critical time for appropriate health decisions occurs during hospital discharge planning with nursing staff. However, little is known how the 89% of elderly living at home make decisions regarding their health care. Research into older adults' management of chronic conditions emerges as an important step to potentially encourage symptom monitoring, prevent missed care and detect deterioration...
January 10, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29321011/attractive-toxic-sugar-baits-for-controlling-mosquitoes-a-qualitative-study-in-bagamoyo-tanzania
#14
Marta Ferreira Maia, Frank Chelestino Tenywa, Hannah Nelson, Athumani Kambagha, Abigail Ashura, Ibrahim Bakari, Deogratis Mruah, Aziza Simba, Ally Bedford
BACKGROUND: Malaria elimination is unlikely to be achieved without the implementation of new vector control interventions capable of complementing insecticide-treated nets and indoor residual spraying. Attractive-toxic sugar baits (ATSBs) are considered a new vector control paradigm. They are technologically appropriate as they are simple and affordable to produce. ATSBs kill both female and male mosquitoes attracted to sugar feed on a sugary solution containing a mosquitocidal agent and may be used indoors or outdoors...
January 10, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29320966/evaluating-barriers-to-adopting-telemedicine-worldwide-a-systematic-review
#15
Clemens Scott Kruse, Priyanka Karem, Kelli Shifflett, Lokesh Vegi, Karuna Ravi, Matthew Brooks
Introduction and objective Studies on telemedicine have shown success in reducing the geographical and time obstacles incurred in the receipt of care in traditional modalities with the same or greater effectiveness; however, there are several barriers that need to be addressed in order for telemedicine technology to spread. The aim of this review is to evaluate barriers to adopting telemedicine worldwide through the analysis of published work. Methods The authors conducted a systematic literature review by extracting the data from the Cumulative Index of Nursing and Allied Health Literature (CINAHL) and PubMed (MEDLINE) research databases...
January 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29320671/cognitive-impairment-during-pregnancy-a-meta-analysis
#16
Sasha J Davies, Jarrad Ag Lum, Helen Skouteris, Linda K Byrne, Melissa J Hayden
OBJECTIVES: Many women report declines in cognitive function during pregnancy, but attempts to empirically evaluate such changes have yielded inconsistent results. We aimed to determine whether pregnancy is associated with objective declines in cognitive functioning, and to assess the progression of any declines during pregnancy. STUDY DESIGN: We undertook a meta-analysis, applying a random effects model, of 20 studies that have reported quantitative relationships between pregnancy and changes in cognition...
January 15, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29317990/artefactual-angulated-lesion-on-angiography-a-case-report-and-review-of-literature
#17
Sadat Ali Edroos, Jeremy William Sayer
We present a case of a patient who presented with chest pain, and on diagnostic coronary angiography appeared to have a grossly angulated yet significant coronary stenosis. This was proven to be an artefactual appearance on further assessment with intravascular ultrasound imaging. We describe the causes and associations of coronary tortuosity with other arteriopathy, and highlight challenges in the interpretation of tortuous vessels to accurately assess luminal narrowing and suitability for coronary intervention...
December 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/29316887/how-do-informal-information-sources-influence-women-s-decision-making-for-birth-a-meta-synthesis-of-qualitative-studies
#18
Ruth A Sanders, Kenda Crozier
BACKGROUND: Women approach birth using various methods of preparation drawing from conventional healthcare providers alongside informal information sources (IIS) outside the professional healthcare context. An investigation of the forms in which these informal information sources are accessed and negotiated by women, and how these disconnected and often conflicting elements influence women's decision-making process for birth have yet to be evaluated. The level of antenatal preparedness women feel can have significant and long lasting implications on their birth experience and transition into motherhood and beyond...
January 10, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29316548/determinants-of-dental-care-attendance-during-pregnancy-a-systematic-review
#19
Juliana Schaia Rocha, Letícia Yumi Arima, Renata Iani Werneck, Samuel Jorge Moysés, Márcia Helena Baldani
Despite the fact that dental care attendance during pregnancy has been recommended by guidelines and institutions, the demand for dental services is still low among pregnant women. The aim of this study was to identify and analyze the determinants of dental care attendance during pregnancy. We performed a systematic literature search in the electronic databases PubMed, Scopus, Web of Science, Latin American and Caribbean Health Sciences Literature, Brazilian Library in Dentistry, Cumulative Index to Nursing and Allied Health Literature, and Medline using relevant keywords...
January 10, 2018: Caries Research
https://www.readbyqxmd.com/read/29315727/considerations-for-optimal-blood-pressure-goals-in-the-elderly-population-a-review-of-emergent-evidence
#20
Diana X Cao, Rebecca J C Tran
Recent hypertension clinical trials and national guideline updates have created a debate on the most appropriate treatment goals in elderly patients with hypertension. In 2014, recommendations by the Eighth Joint National Committee (JNC 8) allowed a more lenient goal for patients 60 years and older compared with previous guidelines. Since then, several large clinical trials and meta-analyses have added more information regarding strict versus lenient treatment goals. Most recently, the American College of Cardiology and American Heart Association Task Force published their highly-anticipated hypertension guideline developed in conjunction with nine additional interdisciplinary organizations...
January 8, 2018: Pharmacotherapy
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