keyword
MENU ▼
Read by QxMD icon Read
search

Sensory deprivation

keyword
https://www.readbyqxmd.com/read/29346758/size-dependent-axonal-bouton-dynamics-following-visual-deprivation-in%C3%A2-vivo
#1
Rosanna P Sammons, Claudia Clopath, Samuel J Barnes
Persistent synapses are thought to underpin the storage of sensory experience, yet little is known about their structural plasticity in vivo. We investigated how persistent presynaptic structures respond to the loss of primary sensory input. Using in vivo two-photon (2P) imaging, we measured fluctuations in the size of excitatory axonal boutons in L2/3 of adult mouse visual cortex after monocular enucleation. The average size of boutons did not change after deprivation, but the range of bouton sizes was reduced...
January 16, 2018: Cell Reports
https://www.readbyqxmd.com/read/29288837/does-eye-velocity-due-to-infantile-nystagmus-deprive-visual-acuity-development
#2
John P Kelly, James O Phillips, Avery H Weiss
PURPOSE: To use eye movement recordings of young children to determine whether eye velocity from infantile nystagmus (IN) deprives the developing visual system of normal visual acuity. METHOS: The video-oculography recordings and visual acuity measurements (including Teller cards) of 15 children ≤6.0 years of age with IN without visual sensory disease (idiopathic IN) were reviewed retrospectively. Eye velocity that would limit visual acuity development was predicted from both empirical adult data adjusted for age and a temporal limitation model using published photoreceptor density data with age...
December 27, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29287884/effects-of-transient-auditory-deprivation-during-critical-periods-on-the-development-of-auditory-temporal-processing
#3
Bong Jik Kim, Jungyoon Kim, Il-Yong Park, Jae Yun Jung, Myung-Whan Suh, Seung-Ha Oh
OBJECTIVES: The central auditory pathway matures through sensory experiences and it is known that sensory experiences during periods called critical periods exert an important influence on brain development. The present study aimed to investigate whether temporary auditory deprivation during critical periods (CPs) could have a detrimental effect on the development of auditory temporal processing. MATERIALS AND METHODS: Twelve neonatal rats were randomly assigned to control and study groups; Study group experienced temporary (18-20 days) auditory deprivation during CPs (Early deprivation study group)...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29247462/cross-modal-refinement-of-visual-performance-after-brief-somatosensory-deprivation-in-adult-mice
#4
Manuel Teichert, Marcel Isstas, Steven Wenig, Christoph Setz, Konrad Lehmann, Jürgen Bolz
It is well established that the congenital lack of one sensory modality enhances functionality in the spared senses. However, whether a late onset deprivation of one sense leads to such alterations is largely unknown. Here, we investigated whether a somatosensory deprivation induced by bilateral whisker removal affects visual acuity and contrast sensitivity in fully adult mice. Using the visual cortex dependent visual water task, we found that a brief somatosensory deprivation markedly improved behavioral visual acuity and contrast sensitivity by about 40%...
December 15, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29234064/homeostatic-plasticity-and-synaptic-scaling-in-the-adult-mouse-auditory-cortex
#5
Manuel Teichert, Lutz Liebmann, Christian A Hübner, Jürgen Bolz
It has been demonstrated that sensory deprivation results in homeostatic adjustments recovering neuronal activity of the deprived cortex. For example, deprived vision multiplicatively scales up mEPSC amplitudes in the primary visual cortex, commonly referred to as synaptic scaling. However, whether synaptic scaling also occurs in auditory cortex after auditory deprivation remains elusive. Using periodic intrinsic optical imaging in adult mice, we show that conductive hearing loss (CHL), initially led to a reduction of primary auditory cortex (A1) responsiveness to sounds...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29212538/a-pilot-investigation-of-audiovisual-processing-and-multisensory-integration-in-patients-with-inherited-retinal-dystrophies
#6
Mark H Myers, Alessandro Iannaccone, Gavin M Bidelman
BACKGROUND: In this study, we examined audiovisual (AV) processing in normal and visually impaired individuals who exhibit partial loss of vision due to inherited retinal dystrophies (IRDs). METHODS: Two groups were analyzed for this pilot study: Group 1 was composed of IRD participants: two with autosomal dominant retinitis pigmentosa (RP), two with autosomal recessive cone-rod dystrophy (CORD), and two with the related complex disorder, Bardet-Biedl syndrome (BBS); Group 2 was composed of 15 non-IRD participants (controls)...
December 7, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29204664/-central-and-peripheral-aspects-of-noise-induced-hearing-loss
#7
REVIEW
D Basta, M Gröschel, A Ernst
Noise is an important socioeconomic problem in industrialized countries. Development of efficient treatment options for the audiological phenomena resulting from noise-induced hearing loss requires in-depth understanding of the underlying damage mechanisms causing peripheral and central nervous changes. Mechanical damage, ischemia and excitotoxicity are mainly responsible for noise-induced cell death and biophysical changes in the cochlea. Auditory synaptopathy is an additional consequence. Besides these cochlear pathologies, noise exposure leads to extensive changes within the central auditory pathway...
December 4, 2017: HNO
https://www.readbyqxmd.com/read/29197166/early-postnatal-development-of-electrophysiological-and-histological-properties-of-sensory-sural-nerves-in-male-rats-that-were-maternally-deprived-and-artificially-reared-role-of-tactile-stimulation
#8
Rene Zempoalteca, Mercedes G Porras, Suelem Moreno-Pérez, Gabriela Ramirez-Funez, Elsa L Aguirre-Benítez, Margarita González Del Pliego, Silvia Mariscal-Tovar, Ma Eugenia Mendoza-Garrido, Kurt Leroy Hoffman, Ismael Jiménez-Estrada, Angel I Melo
Early adverse experiences disrupt brain development and behavior, but little is known about how such experiences impact on the development of the peripheral nervous system. Recently, we found alterations in the electrophysiological and histological characteristics of the sensory sural (SU) nerve in maternally-deprived, artificially-reared (AR) adult male rats, as compared to maternally-reared (MR) control rats. In the present study, our aim was to characterize the ontogeny of these alterations. Thus, male pups of 4 postnatal days (PND) were 1) artificially reared (AR group), 2) artificially reared and received daily tactile stimulation to the body and anogenital region (AR-Tactile group); or 3) reared by their mother (MR group)...
December 2, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/29196586/implementing-a-multicomponent-intervention-to-prevent-delirium-among-critically-ill-patients
#9
Felipe Martínez, Ana María Donoso, Carla Marquez, Eduardo Labarca
BACKGROUND: Delirium is common among the critically ill. Nonpharmacologic interventions are reportedly effective in reducing incident delirium, but limited data specific to this population exist. OBJECTIVES: To assess the efficacy and describe the implementation strategy of a multicomponent intervention to prevent delirium in an intensive care unit. METHODS: A before-and-after study was conducted in an intensive care unit between May 2014 through August 2015...
December 2017: Critical Care Nurse
https://www.readbyqxmd.com/read/29180513/glucose-deprivation-induces-primary-cilium-formation-through-mtorc1-inactivation
#10
Kengo Takahashi, Tomoaki Nagai, Shuhei Chiba, Keiko Nakayama, Kensaku Mizuno
Primary cilia are antenna-like sensory organelles extending from the surface of many cell types and play critical roles in tissue development and homeostasis. Here, we examined the effect of nutrient status on primary cilium formation. Glucose deprivation significantly increased the number of ciliated cells under both serum-fed and -starved conditions. Glucose deprivation-induced ciliogenesis was suppressed by overexpression of Rheb, an activator of mammalian target of rapamycin complex-1 (mTORC1). Inactivation of mTORC1 by rapamycin treatment or Raptor knockdown significantly promoted ciliogenesis...
November 27, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29161626/the-effect-of-augmented-somatosensory-feedback-on-standing-postural-sway
#11
Angela Smalley, Scott C White, Robert Burkard
Impaired balance resulting from reduced postural control occurs with aging and various medical conditions. Sensory input for balance control is provided by the visual, vestibular and somatosensory systems. Previous research suggests that increased proprioceptive feedback from various lower extremity devices improves balance. Mixed results have been reported with the use of orthoses such as ankle foot orthoses (AFOs). In this study, 20 healthy subjects wore footplates in their shoes or straps around their lower legs in order to imitate the somatosensory feedback produced by wearing AFOs, but without providing ankle restriction...
November 14, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29155975/induced-cortical-responses-require-developmental-sensory-experience
#12
Prasandhya Astagiri Yusuf, Peter Hubka, Jochen Tillein, Andrej Kral
Sensory areas of the cerebral cortex integrate the sensory inputs with the ongoing activity. We studied how complete absence of auditory experience affects this process in a higher mammal model of complete sensory deprivation, the congenitally deaf cat. Cortical responses were elicited by intracochlear electric stimulation using cochlear implants in adult hearing controls and deaf cats. Additionally, in hearing controls, acoustic stimuli were used to assess the effect of stimulus mode (electric versus acoustic) on the cortical responses...
November 16, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29144967/a-local-rebalancing-act-leads-to-global-benefit
#13
Ju Lu, Yi Zuo
Barnes et al. (2017) reveal that in the visual cortex of sensory-deprived mice, dendritic spine enlargement correlates with recent spine loss from the same dendritic branch. Such branch-specific homeostatic plasticity highlights dendritic branches as key computational units.
November 15, 2017: Neuron
https://www.readbyqxmd.com/read/29118195/binocular-deprivation-induces-both-age-dependent-and-age-independent-forms-of-plasticity-in-parvalbumin-inhibitory-neuron-visual-response-properties
#14
Berquin D Feese, Diego E Pafundo, Meredith N Schmehl, Sandra J Kuhlman
Activity of cortical inhibitory interneurons is rapidly reduced in response to monocular deprivation during the critical period for ocular dominance plasticity and in response to salient events encountered during learning. In the case of primary sensory cortex, a decrease in mean evoked firing rate of parvalbumin-positive (PV) inhibitory neurons is causally linked to a reorganization of excitatory networks following sensory perturbation. Converging evidence indicates that it is deprivation, and not an imbalance between open and closed eye inputs, that triggers rapid plasticity in PV neurons...
November 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29111363/absolute-not-relative-interocular-luminance-modulates-sensory-eye-dominance-plasticity-in-adults
#15
Zhimo Yao, Zhifen He, Yonghua Wang, Fan Lu, Jia Qu, Jiawei Zhou, Robert F Hess
If one eye is patched for a period of 2.5 h in human adults, transient changes in sensory eye dominance result with the previously patched eye's contribution being strengthened. Similar changes result from opaque and translucent occlusion suggesting that it is the deprivation of contrast not luminance information that drives these transient shift of sensory eye dominance. However, this does not rule out the possibility that luminance deprivation per se cannot produce changes in sensory eye dominance, indeed based on what we know of the physiology, where the contrast gain of visual neurons is luminance dependent, one would expect it should...
October 27, 2017: Neuroscience
https://www.readbyqxmd.com/read/29107520/deprivation-induced-homeostatic-spine-scaling-in%C3%A2-vivo-is-localized-to-dendritic-branches-that-have-undergone-recent-spine-loss
#16
Samuel J Barnes, Eleonora Franzoni, R Irene Jacobsen, Ferenc Erdelyi, Gabor Szabo, Claudia Clopath, Georg B Keller, Tara Keck
Synaptic scaling is a key homeostatic plasticity mechanism and is thought to be involved in the regulation of cortical activity levels. Here we investigated the spatial scale of homeostatic changes in spine size following sensory deprivation in a subset of inhibitory (layer 2/3 GAD65-positive) and excitatory (layer 5 Thy1-positive) neurons in mouse visual cortex. Using repeated in vivo two-photon imaging, we find that increases in spine size are tumor necrosis factor alpha (TNF-α) dependent and thus are likely associated with synaptic scaling...
November 15, 2017: Neuron
https://www.readbyqxmd.com/read/29094306/early-sensory-experience-influences-the-development-of-multisensory-thalamocortical-and-intracortical-connections-of-primary-sensory-cortices
#17
Julia U Henschke, Anja M Oelschlegel, Frank Angenstein, Frank W Ohl, Jürgen Goldschmidt, Patrick O Kanold, Eike Budinger
The nervous system integrates information from multiple senses. This multisensory integration already occurs in primary sensory cortices via direct thalamocortical and corticocortical connections across modalities. In humans, sensory loss from birth results in functional recruitment of the deprived cortical territory by the spared senses but the underlying circuit changes are not well known. Using tracer injections into primary auditory, somatosensory, and visual cortex within the first postnatal month of life in a rodent model (Mongolian gerbil) we show that multisensory thalamocortical connections emerge before corticocortical connections but mostly disappear during development...
November 1, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29053746/external-auditory-exostoses-and-hearing-loss-in-the-shanidar-1-neandertal
#18
Erik Trinkaus, Sébastien Villotte
The Late Pleistocene Shanidar 1 older adult male Neandertal is known for the crushing fracture of his left orbit with a probable reduction in vision, the loss of his right forearm and hand, and evidence of an abnormal gait, as well as probable diffuse idiopathic skeletal hyperostosis. He also exhibits advanced external auditory exostoses in his left auditory meatus and larger ones with complete bridging across the porus in the right meatus (both Grade 3). These growths indicate at least unilateral conductive hearing (CHL) loss, a serious sensory deprivation for a Pleistocene hunter-gatherer...
2017: PloS One
https://www.readbyqxmd.com/read/29050394/cortical-neurons-and-networks-are-dormant-but-fully-responsive-during-isoelectric-brain-state
#19
Tristan Altwegg-Boussac, Adrien E Schramm, Jimena Ballestero, Fanny Grosselin, Mario Chavez, Sarah Lecas, Michel Baulac, Lionel Naccache, Sophie Demeret, Vincent Navarro, Séverine Mahon, Stéphane Charpier
A continuous isoelectric electroencephalogram reflects an interruption of endogenously-generated activity in cortical networks and systematically results in a complete dissolution of conscious processes. This electro-cerebral inactivity occurs during various brain disorders, including hypothermia, drug intoxication, long-lasting anoxia and brain trauma. It can also be induced in a therapeutic context, following the administration of high doses of barbiturate-derived compounds, to interrupt a hyper-refractory status epilepticus...
September 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29036852/rehabilitation-modality-and-onset-differentially-influence-whisker-sensory-hypersensitivity-after-diffuse-traumatic-brain-injury-in-the-rat
#20
Theresa Currier Thomas, Ellen Magee Stockhausen, L Matthew Law, Aida Khodadad, Jonathan Lifshitz
BACKGROUND: As rehabilitation strategies advance as therapeutic interventions, the modality and onset of rehabilitation after traumatic brain injury (TBI) are critical to optimize treatment. Our laboratory has detected and characterized a late-onset, long-lasting sensory hypersensitivity to whisker stimulation in diffuse brain-injured rats; a deficit that is comparable to visual or auditory sensory hypersensitivity in humans with an acquired brain injury. OBJECTIVE: We hypothesize that the modality and onset of rehabilitation therapies will differentially influence sensory hypersensitivity in response to the Whisker Nuisance Task (WNT) as well as WNT-induced corticosterone (CORT) stress response in diffuse brain-injured rats and shams...
October 9, 2017: Restorative Neurology and Neuroscience
keyword
keyword
69616
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"