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https://www.readbyqxmd.com/read/29351462/maximal-strength-training-induced-improvements-in-forearm-work-efficiency-are-associated-with-reduced-blood-flow
#1
Ole Kristian Berg, Stian Kwak Nyberg, Tobias Midtvedt Windedal, Eivind Wang
Maximal strength training (MST) improves work efficiency. However, since blood flow is greatly dictated by muscle contractions in arms during exercise, and vascular conductance is lower, it has been indicated that arms rely more upon adapting oxygen extraction than legs in response to the enhanced work efficiency. Thus, to investigate if metabolic and vascular responses are arm-specific, we utilized Doppler-ultrasound and a catheter placed in the subclavian vein to measure blood flow and a-vO2diff during steady state work in seven young males (24{plus minus}3(SD) years) following six-weeks of handgrip MST...
December 29, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29350323/william-e-vidaver-1921-2017-an-innovator-enthusiastic-scientist-inspiring-teacher-and-a-wonderful-friend
#2
A H Jay Burr, Aaron Vidaver, Ulrich Schreiber, Doug Bruce, Danielle J Donnelly
William (Bill) E. Vidaver (February 2, 1921-August 31, 2017), who did his Ph.D. with Laurence (Larry) R. Blinks at Stanford (1964) and a postdoc with C. Stacy French (1965), taught and did research at Simon Fraser University (SFU) for almost 30 years. Here he published over 80 papers in photosynthesis-related areas co-authored by his graduate students, postdocs, visiting professors and SFU colleagues. He developed a unique high-pressure cuvette for the study of oxygen exchange and studied high-pressure effects in photosynthesis...
January 19, 2018: Photosynthesis Research
https://www.readbyqxmd.com/read/29349536/oxygen-uptake-efficiency-slope-and-prediction-of-post-operative-morbidity-and-mortality-in-patients-with-lung-cancer
#3
Sertaç Yakal, Sevtün Sofyalı, Berker Özkan, Safinaz Yıldız, Alper Toker, Erdem Kasikcioglu
OBJECTIVE: Peak oxygen consumption is a very valuable cardiopulmonary functional parameter in pre-operative evaluation of patients with lung cancer. However, it has several critical limitations for operability decision due to failure in achieving maximal level of exercise test for cases. The aim of this study was to reveal the importance of more accurate cardiopulmonary parameters that can be calculated from data of submaximal level test, such as oxygen uptake efficiency slope (OUES) and to determine whether it could be used in the operability decision phase for borderline cases by means of morbidity and mortality...
January 18, 2018: Lung
https://www.readbyqxmd.com/read/29348676/mir-137-regulates-ferroptosis-by-targeting-glutamine-transporter-slc1a5-in-melanoma
#4
Meiying Luo, Longfei Wu, Kexin Zhang, Hong Wang, Tian Zhang, Lucas Gutierrez, Douglas O'Connell, Peng Zhang, Yu Li, Tongtong Gao, Wenyan Ren, Yongfei Yang
Ferroptosis is a regulated form of cell death driven by small molecules or conditions that induce lipid-based reactive oxygen species (ROS) accumulation. This form of iron-dependent cell death is morphologically and genetically distinct from apoptosis, necroptosis, and autophagy. miRNAs are known to play crucial roles in diverse fundamental biological processes. However, to date no study has reported miRNA-mediated regulation of ferroptosis. Here we show that miR-137 negatively regulates ferroptosis by directly targeting glutamine transporter SLC1A5 in melanoma cells...
January 18, 2018: Cell Death and Differentiation
https://www.readbyqxmd.com/read/29345858/cardiopulmonary-fitness-is-strongly-associated-with-body-cell-mass-and-fat-free-mass
#5
Armin Köhler, Ryan King, Martin Bahls, Stefan Groß, Antje Steveling, Simone Gärtner, Sabine Schipf, Sven Gläser, Henry Völzke, Stephan B Felix, Marcello Ricardo Paulista Markus, Marcus Dörr
BACKGROUND: Peak oxygen uptake (VO2peak) is commonly indexed by total body weight (TBW) to determine cardiopulmonary fitness (CPF). This approach may lead to misinterpretation, particularly in obese subjects. We investigated the normalization of VO2peak by different body composition markers. METHODS: We analyzed combined data of 3,848 subjects (1,914 women; 49.7%), aged 20-90, from two independent cohorts of the population-based Study of Health in Pomerania (SHIP-2 and SHIP-TREND)...
January 18, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29345213/matcha-green-tea-drinks-enhance-fat-oxidation-during-brisk-walking-in-females
#6
Mark Elisabeth Theodorus Willems, Mehmet Akif Şahin, Matthew David Cook
Intake of the catechin epigallocatechin gallate and caffeine has been shown to enhance exercise-induced fat oxidation. Matcha green tea powder contains catechins and caffeine and is consumed as a drink. We examined the effect of Matcha green tea drinks on metabolic, physiological and perceived intensity responses during brisk walking. Thirteen females (age: 27±8 yr, body mass: 65±7 kg, height: 166±6 cm) volunteered. Resting metabolic equivalent (1-MET) was measured using Douglas bags (1-MET: 3.4±0.3 ml·kg-1·min-1)...
January 18, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29344916/the-acute-effects-of-erythromycin-and-oxytetracycline-on-enhanced-biological-phosphorus-removal-system-shift-in-bacterial-community-structure
#7
Zhetai Hu, Peide Sun, Jingyi Han, Ruyi Wang, Liang Jiao, Pengfei Yang, Jing Cai
Since extensive application, an increasing amount of antibiotics has been released into wastewater treatment plants. In this study, the enhanced biological phosphorus removal (EBPR) system was fed with synthetic wastewater containing erythromycin (ERY) and oxytetracycline (OTC) for 7 days to evaluate the variations of solution ortho-P (SOP), volatile fatty acid (VFA), poly-bhydroxyalkanoates (PHAs), specific oxygen uptake rater (SOUR), and microbial community in the EBPR system. The obtained results showed that the P-removal efficiency decreased to 0...
January 18, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29341977/elemental-composition-at-silicone-hydrogel-contact-lens-surfaces
#8
Jessica Rex, Timothy Knowles, Xueying Zhao, Jessie Lemp, Cecile Maissa, Scott S Perry
OBJECTIVES: The outermost surface composition of 11 silicone hydrogel (SiHy) lenses was measured using X-ray photoelectron spectroscopy (XPS) to understand differences in wettability and potential interactions within an ocular environment. The SiHy lenses tested included balafilcon A, lotrafilcon A, lotrafilcon B, senofilcon A, comfilcon A, and somofilcon A reusable 2-week or monthly replacement lenses and delefilcon A, samfilcon A, narafilcon A, stenfilcon A, and somofilcon A daily disposable lenses...
January 15, 2018: Eye & Contact Lens
https://www.readbyqxmd.com/read/29340005/comparison-of-aerobic-performance-testing-protocols-in-elite-male-wheelchair-basketball-players
#9
Bartosz Molik, Andrzej Kosmol, Natalia Morgulec-Adamowicz, Judit Lencse-Mucha, Anna Mróz, Karol Gryko, Jolanta Marszałek
In wheelchair sports, aerobic performance is commonly assessed with the use of an arm crank ergometer (ACE), a wheelchair ergometer (WCE) or a wheelchair treadmill (WCT). There are different protocols to identify peak oxygen uptake in wheelchair sports; however, only a few protocols have been applied to evaluate these conditions in wheelchair basketball players. The purpose of this study was to compare physiological responses during maximal exercise testing with the use of ACE and WCT in wheelchair basketball players...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339995/physical-performance-and-anthropometric-characteristics-of-male-south-african-university-soccer-players
#10
Alliance Kubayi, Yvonne Paul, Prescott Mahlangu, Abel Toriola
Soccer is the most popular sport worldwide. Despite its global acclaim, scientific studies of soccer have tended to focus on tactics and techniques, thereby neglecting the physical and physiological profile of the players. Therefore, the purpose of this study was to examine physical and anthropometric characteristics of male South African university soccer players. Twenty-seven male soccer players aged 19 to 24 (mean age: 22.1 years; s = 1.5 years) volunteered to participate in the study. The results showed that goalkeepers (77...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339061/dose-dependent-photochemical-photothermal-toxicity-of-indocyanine-green-based-therapy-on-three-different-cancer-cell-lines
#11
Mustafa Kemal Ruhi, Ayşe Ak Can, Murat Gülsoy
The Food and Drug Administration-approved Indocyanine Green can be used as a photosensitizer to kill cancer cells selectively. Although indocyanine green is advantageous as a photosensitizer in terms of strong absorption in the near-infrared region, indocyanine green-based cancer treatment is still not approved as a clinical method. Some reasons for this are aggregation at high concentrations, rapid clearance of the photosensitizer from the body, low singlet oxygen quantum yield, and the uncertainty concerning its action mechanism...
January 12, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29338771/regulation-of-aquaporins-in-plants-under-stress
#12
REVIEW
Ranganathan Kapilan, Maryam Vaziri, Janusz J Zwiazek
Aquaporins (AQP) are channel proteins belonging to the Major Intrinsic Protein (MIP) superfamily that play an important role in plant water relations. The main role of aquaporins in plants is transport of water and other small neutral molecules across cellular biological membranes. AQPs have remarkable features to provide an efficient and often, specific water flow and enable them to transport water into and out of the cells along the water potential gradient. Plant AQPs are classified into five main subfamilies including the plasma membrane intrinsic proteins (PIPs), tonoplast intrinsic proteins (TIPs), nodulin 26 like intrinsic proteins (NIPs), small basic intrinsic proteins (SIPs) and X intrinsic proteins (XIPs)...
January 16, 2018: Biological Research
https://www.readbyqxmd.com/read/29338613/combined-systems-of-different-antibiotics-with-nano-cuo-against-escherichia-coli-and-the-mechanisms-involved
#13
Yahui Zhang, Lin Wang, Xiang Xu, Fang Li, Qingsheng Wu
AIM: The combined efficacy of CuO nanoparticles (NPs) with 22 kinds of antibiotics against Escherichia coli was systematic studied, and CuO with cephalexin synergistic system was screened out. METHODS: Antimicrobial susceptibility test included disk diffusion test, checkerboard method and time-kill assay. The interactions of CuO NPs and antibiotics were analyzed by x-ray photoelectron spectroscopy, Fourier transform infrared spectra and Zeta. The interactions between bacteria and antibacterial agents were studied by surface plasmon resonance sensor for the first time...
January 17, 2018: Nanomedicine
https://www.readbyqxmd.com/read/29338134/retinal-oximetry-is-affected-in-multiple-sclerosis
#14
Anna Bryndis Einarsdottir, Olof Birna Olafsdottir, Haukur Hjaltason, Sveinn Hakon Hardarson
PURPOSE: Structural and physiological abnormalities have been reported in the retina in patients with multiple sclerosis (MS). Retinal oximetry has recently detected changes in retinal oxygen metabolism in Alzheimer's disease and mild cognitive impairment. Our goal was to determine whether oxygen saturation in retinal blood vessels of patients with patients is different from that of a healthy population. METHODS: Oxygen saturation of haemoglobin was measured in retinal blood vessels, using imaging with spectrophotometric noninvasive retinal oximeter...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29334615/hemodynamic-and-metabolic-responses-to-self-paced-and-ramp-graded-exercise-testing-protocols
#15
Nicholas M Beltz, Fabiano Amorim, Ann L Gibson, Jeffrey M Janot, Len Kravitz, Christine M Mermier, Nathan Cole, Terence A Moriarty, Tony P Nunez, Sam Trigg, Lance Dalleck
PURPOSE: Recent examinations have shown lower maximal oxygen uptake (VO2max) during traditional ramp (RAMP) compared to self-paced (SPV) graded exercise testing (GXT) attributed to differences in cardiac ouput. The current study examined the differences in hemodyamic and metabolic responses between RAMP and SPV during treadmill exercise. METHODS: Sixteen recreationally trained men (23.7±3.0 yrs) completed two separate treadmill GXT protocols. SPV consisted of five 2-min stages (10 min total) of increasing speed clamped by the Borg RPE6-20 scale...
January 15, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29334157/elevated-sympathetic-vasomotor-outflow-in-response-to-increased-inspiratory-muscle-activity-during-exercise-is-less-in-young-women-compared-with-men
#16
Keisho Katayama, Joshua R Smith, Kanako Goto, Kaori Shimizu, Mitsuru Saito, Koji Ishida, Teruhiko Koike, Satoshi Iwase, Craig A Harms
We compared changes in muscle sympathetic nerve activity (MSNA) and cardiovascular variables during leg cycle exercise with increased inspiratory muscle resistance in men and women. We hypothesized that sympathetic vasomotor outflow during exercise with increased inspiratory resistance would be attenuated in young women compared with age-matched men. Eight women and seven men completed the study. The subjects performed two 10-min exercise bouts at 40% peak oxygen uptake using a cycle ergometer in a semirecumbent position [spontaneous breathing for 5 min and voluntary hyperventilation with or without inspiratory resistive breathing for 5 min (breathing frequency: 50 breaths min-1 with a 50% duty cycle, inspiratory resistance: 30% of maximal inspiratory pressure)]...
January 15, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29334005/physiological-correlations-with-short-medium-and-long-cycling-time-trial-performance
#17
Fernando K Borszcz, Artur F Tramontin, Kristopher M de Souza, Lorival J Carminatti, Vitor P Costa
PURPOSE: Several studies have demonstrated that physiological variables predict cycling endurance performance. However, it is still unclear whether the predictors will change over different performance durations. The aim of this study was to assess the correlations between physiological variables and cycling time trials with different durations. METHODS: Twenty trained male cyclists (maximal oxygen uptake [VO2max] = 60.5 ± 5.6 mL/kg/min) performed 4 separate experimental trials during a 2-week period...
January 15, 2018: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29331919/removal-of-pharmaceutical-pollutants-from-synthetic-wastewater-using-chemically-modified-biomass-of-green-alga-scenedesmus-obliquus
#18
Mohamed E M Ali, Azza M Abd El-Aty, Mohamed I Badawy, Rizka K Ali
Pharmaceutical compounds are considered emerging environmental pollutants that have a potential harmful impact on environment and human health. In this study, the biomass of alga (Scenedesmus obliquus) was modified using alkaline solution, and used for the biosorption of tramadol (TRAM) and other pharmaceuticals. The adsorption kinetics and isotherms were investigated. The obtained results reveal high adsorption capacity of tramadol over modified algal biomass (MAB) after 45min with removal percentage of 91%...
January 11, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29330966/static-hyperinflation-is-associated-with-ventilatory-limitation-and-exercise-tolerance-in-adult-cystic-fibrosis
#19
Daniel Stevens
INTRODUCTION: Lung hyperinflation is a potential mechanism limiting exercise tolerance. However, available data on the impact of static hyperinflation on exercise performance in adult cystic fibrosis is lacking. Furthermore, the relative contribution of both static and dynamic hyperinflation to exercise performance is unknown. OBJECTIVES: To determine the impact of static hyperinflation on exercise tolerance and lung dynamics in adult cystic fibrosis. METHODS: Clinical data of 107 adult patients with cystic fibrosis, including pulmonary function, lung volumes, and cardiopulmonary exercise from the Toronto Cystic Fibrosis database were collected and analyzed...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29330794/hypoxia-mediated-in-vivo-tumor-glucose-uptake-measurement-and-analysis
#20
Surendra K Shukla, Scott E Mulder, Pankaj K Singh
Most solid tumors are hypoxic in nature due to the limited supply of oxygen to internal tissues. Hypoxia plays an important role in metabolic adaptations of tumors that contribute significantly to cancer pathogenesis. Among the several metabolic alterations induced by hypoxia, hypoxia-mediated increased glucose uptake serves as the hallmark of metabolic reprogramming. Hypoxia-mediated stabilization of hypoxia-inducible factor-1 alpha (HIF-1α) transcription factor leads to altered expression of several glycolytic genes and glucose transporters, which results in increased glucose uptake by tumor cells...
2018: Methods in Molecular Biology
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