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https://www.readbyqxmd.com/read/28069563/brief-cognitive-behavioural-therapy-for-patients-in-the-community-with-schizophrenia-randomised-controlled-trial-in-beijing-china
#1
Zhi-Hua Guo, Zhan-Jiang Li, Yun Ma, Jing Sun, Jun-Hua Guo, Wen-Xiu Li, Zhi-Qiang Wang, Hui-Li Xu, Roger M K Ng, Douglas Turkington, David Kingdon
BACKGROUND: Brief cognitive-behavioural therapy (CBT) is an emerging treatment for schizophrenia in community settings; however, further trials are needed, especially in non-Western countries. AIMS: To test the effects of brief CBT for Chinese patients with schizophrenia in the community (trial registration: ChiCTR-TRC-13003709). METHOD: A total of 220 patients with schizophrenia from four districts of Beijing were randomly assigned to either brief CBT plus treatment as usual (TAU) or TAU alone...
January 9, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28033512/the-beliefs-about-paranoia-scale-confirmatory-factor-analysis-and-tests-of-a-metacognitive-model-of-paranoia-in-a-clinical-sample
#2
Elizabeth K Murphy, Sarah Tully, Melissa Pyle, Andrew I Gumley, David Kingdon, Matthias Schwannauer, Douglas Turkington, Anthony P Morrison
This study aimed to confirm the factor structure of the Beliefs about Paranoia Scale (BaPS), a self-report measure to assess metacognitive beliefs about paranoia, and to test hypotheses of a metacognitive model. We hypothesised that positive and negative beliefs about paranoia would be associated with severity of suspiciousness, and that the co-occurrence of positive and negative beliefs would be associated with increased suspiciousness. A total of 335 patients meeting criteria for a schizophrenia spectrum disorder completed the BaPS, the Positive and Negative Syndromes Scale (PANSS), and the Psychotic Symptom Rating Scales (PSYRATS)...
November 12, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28003288/protocol-for-a-multicentre-study-to-assess-feasibility-acceptability-effectiveness-and-direct-costs-of-triumph-treatment-and-recovery-in-psychosis-integrated-care-pathway-for-psychosis
#3
Shanaya Rathod, Christie Garner, Alison Griffiths, Borislav D Dimitrov, Katherine Newman-Taylor, Chris Woodfine, Lars Hansen, Paul Tabraham, Karen Ward, Carolyn Asher, Peter Phiri, Farooq Naeem, Pippa North, Tariq Munshi, David Kingdon
INTRODUCTION: Duration of untreated psychosis (time between the onset of symptoms and start of treatment) is considered the strongest predictor of symptom severity and outcome. Integrated care pathways that prescribe timeframes around access and interventions can potentially improve quality of care. METHODS AND ANALYSIS: A multicentre mixed methods study to assess feasibility, acceptability, effectiveness and analysis of direct costs of an integrated care pathway for psychosis...
December 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27902745/utility-of-the-health-of-the-nation-outcome-scales-honos-in-predicting-mental-health-service-costs-for-patients-with-common-mental-health-problems-historical-cohort-study
#4
Conal Twomey, A Matthew Prina, David S Baldwin, Jayati Das-Munshi, David Kingdon, Leonardo Koeser, Martin J Prince, Robert Stewart, Alex D Tulloch, Alarcos Cieza
BACKGROUND: Few countries have made much progress in implementing transparent and efficient systems for the allocation of mental health care resources. In England there are ongoing efforts by the National Health Service (NHS) to develop mental health 'payment by results' (PbR). The system depends on the ability of patient 'clusters' derived from the Health of the Nation Outcome Scales (HoNOS) to predict costs. We therefore investigated the associations of individual HoNOS items and the Total HoNOS score at baseline with mental health service costs at one year follow-up...
2016: PloS One
https://www.readbyqxmd.com/read/27790373/techcare-mobile-assessment-and-therapy-for-psychosis-an-intervention-for-clients-in-the-early-intervention-service-a-feasibility-study-protocol
#5
Nusrat Husain, Nadeem Gire, James Kelly, Joy Duxbury, Mick McKeown, Miv Riley, Christopher Dj Taylor, Peter J Taylor, Richard Emsley, Saeed Farooq, Neil Caton, Farooq Naeem, David Kingdon, Imran Chaudhry
OBJECTIVES: Technological advances in healthcare have shown promise when delivering interventions for mental health problems such as psychosis. The aim of this project is to develop a mobile phone intervention for people with psychosis and to conduct a feasibility study of the TechCare App. METHODS: The TechCare App will assess participant's symptoms and respond with a personalised guided self-help-based psychological intervention with the aim of exploring feasibility and acceptability...
2016: SAGE Open Medicine
https://www.readbyqxmd.com/read/27746054/measuring-common-responses-to-psychosis-assessing-the-psychometric-properties-of-a-new-measure
#6
Sarah Tully, Adrian Wells, Melissa Pyle, Jemma Hudson, Andrew Gumley, David Kingdon, Matthias Schwannauer, Douglas Turkington, Anthony P Morrison
Responses to psychotic experiences are central to cognitive models of psychosis. The current study aimed to develop and validate a self-report measure of common responses to the experience of psychosis. This measure is needed as cognitive and behavioural responses are implicated in the maintenance of psychosis, but there is currently no measure that comprehensively assesses these maintaining factors. The Measure of Common Responses to psychosis (MCR) was developed and utilised in a sample of 487 participants who met criteria for treatment-resistant schizophrenia...
October 13, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27692269/data-science-for-mental-health-a-uk-perspective-on-a-global-challenge
#7
REVIEW
Andrew M McIntosh, Robert Stewart, Ann John, Daniel J Smith, Katrina Davis, Cathie Sudlow, Aiden Corvin, Kristin K Nicodemus, David Kingdon, Lamiece Hassan, Matthew Hotopf, Stephen M Lawrie, Tom C Russ, John R Geddes, Miranda Wolpert, Eva Wölbert, David J Porteous
Data science uses computer science and statistics to extract new knowledge from high-dimensional datasets (ie, those with many different variables and data types). Mental health research, diagnosis, and treatment could benefit from data science that uses cohort studies, genomics, and routine health-care and administrative data. The UK is well placed to trial these approaches through robust NHS-linked data science projects, such as the UK Biobank, Generation Scotland, and the Clinical Record Interactive Search (CRIS) programme...
October 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27496180/design-and-protocol-for-the-focusing-on-clozapine-unresponsive-symptoms-focus-trial-a-randomised-controlled-trial
#8
Melissa Pyle, John Norrie, Matthias Schwannauer, David Kingdon, Andrew Gumley, Douglas Turkington, Rory Byrne, Suzy Syrett, Graeme MacLennan, Robert Dudley, Hamish J McLeod, Helen Griffiths, Samantha Bowe, Thomas R E Barnes, Paul French, Paul Hutton, Linda Davies, Anthony P Morrison
BACKGROUND: For around a third of people with a diagnosis of schizophrenia, the condition proves to respond poorly to treatment with many typical and atypical antipsychotics. This is commonly referred to as treatment-resistant schizophrenia. Clozapine is the only antipsychotic with convincing efficacy for people whose symptoms are considered treatment-resistant to antipsychotic medication. However, 30-40 % of such conditions will have an insufficient response to the drug. Cognitive behavioural therapy has been shown to be an effective treatment for schizophrenia when delivered in combination with antipsychotic medication, with several meta-analyses showing robust support for this approach...
2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27445354/training-to-enhance-psychiatrist-communication-with-patients-with-psychosis-tempo-cluster-randomised-controlled-trial
#9
Rose McCabe, Paula John, Jemima Dooley, Patrick Healey, Annie Cushing, David Kingdon, Stephen Bremner, Stefan Priebe
BACKGROUND: A better therapeutic relationship predicts better outcomes. However, there is no trial-based evidence on how to improve therapeutic relationships in psychosis. AIMS: To test the effectiveness of communication training for psychiatrists on improving shared understanding and the therapeutic relationship (trial registration: ISRCTN94846422). METHOD: In a cluster randomised controlled trial in the UK, 21 psychiatrists were randomised...
December 2016: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/27146475/group-mindfulness-based-intervention-for-distressing-voices-a-pragmatic-randomised-controlled-trial
#10
Paul Chadwick, Clara Strauss, Anna-Marie Jones, David Kingdon, Lyn Ellett, Laura Dannahy, Mark Hayward
Group Person-Based Cognitive Therapy (PBCT) integrates cognitive therapy and mindfulness to target distinct sources of distress in psychosis. The present study presents data from the first randomised controlled trial investigating group PBCT in people distressed by hearing voices. One-hundred and eight participants were randomised to receive either group PBCT and Treatment As Usual (TAU) or TAU only. While there was no significant effect on the primary outcome, a measure of general psychological distress, results showed significant between-group post-intervention benefits in voice-related distress, perceived controllability of voices and recovery...
August 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/26996274/worry-processes-in-patients-with-persecutory-delusions
#11
Helen Startup, Katherine Pugh, Graham Dunn, Jacinta Cordwell, Helen Mander, Emma Černis, Gail Wingham, Katherine Shirvell, David Kingdon, Daniel Freeman
OBJECTIVES: Worry may be common in patients with paranoia and a contributory causal factor in the occurrence of the delusions. A number of psychological mechanisms have been linked to the occurrence of worry in emotional disorders but these are yet to be investigated in psychosis. The primary aim of the study was to test the links between five main worry mechanisms - perseverative thinking, catastrophizing, stop rules, metacognitive beliefs, and intolerance of uncertainty - and the cognitive style of worry in patients with persecutory delusions...
November 2016: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/26971071/cognitive-behavior-therapy-for-psychosis-based-guided-self-help-cbtp-gsh-delivered-by-frontline-mental-health-professionals-results-of-a-feasibility-study
#12
RANDOMIZED CONTROLLED TRIAL
Farooq Naeem, Rupy Johal, Claire McKenna, Shanaya Rathod, Muhammad Ayub, Tania Lecomte, Nusrat Husain, David Kingdon, Saeed Farooq
Availability of Cognitive Behavior Therapy for psychosis (CBTp) is limited in spite of strong evidence base. The purpose of this study was to determine the feasibility of a CBTp based Guided Self-help (CBTp-GSH) in comparison to Treatment As Usual (TAU). The secondary outcomes were a reduction of symptoms of schizophrenia using Positive and Negative Symptom Scale (PANSS) & Disability (WHO DAS 2.0). A total of 33 adults with a DSM-IV diagnosis of schizophrenia was recruited from community mental health services in Kingston, ON, Canada, and randomly assigned to the 12-16week intervention with TAU (Treatment), or TAU alone (Control)...
May 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/26969128/the-efficacy-of-a-new-translational-treatment-for-persecutory-delusions-study-protocol-for-a-randomised-controlled-trial-the-feeling-safe-study
#13
RANDOMIZED CONTROLLED TRIAL
Daniel Freeman, Felicity Waite, Richard Emsley, David Kingdon, Linda Davies, Ray Fitzpatrick, Graham Dunn
BACKGROUND: Persecutory delusions (strong unfounded fears that others intend harm to the person) occur in more than 70 % of the patients diagnosed with schizophrenia. This major psychotic experience is a key clinical target, for which substantial improvement in treatment is needed. Our aim is to use advances in theoretical understanding to develop a much more efficacious treatment that leads to recovery in at least 50 % of people with persistent persecutory delusions. Our cognitive conceptualisation is that persecutory delusions are threat beliefs, developed in the context of genetic and environmental risk, maintained by a number of psychological processes including excessive worry, low self-confidence, intolerance of anxious affect and other internal anomalous experiences, reasoning biases, and safety-seeking strategies...
March 11, 2016: Trials
https://www.readbyqxmd.com/read/26808462/successful-resuscitation-novel-partnership-between-paramedics-and-u-s-coast-guard
#14
David Kingdon, Erin Stapleton, Eric Stahl
In this article, we present a notable case that illustrates a novel partnership between a United States Coast Guard small boat station and a civilian paramedic response unit. Patients who experience medical emergencies in remote environments are at particularly high risk for morbidity and mortality. For the most serious conditions, delayed contact with Advanced Life Support (ALS) has grave results. Typically, these circumstances involve small groups of individuals and cannot be easily predicted. The waters off the coasts of Maui, Hawaii, however, host millions of residents and visitors annually, with activities including swimming, snorkeling, diving, parasailing, and other types of ocean recreation...
May 2016: Prehospital Emergency Care
https://www.readbyqxmd.com/read/26649933/reanalyses-of-turkington-et-al-2014-correcting-errors-and-clarifying-findings
#15
Harry J Sivec, Michael Hewit, Zhenyu Jia, Vicki Montesano, Mark R Munetz, David Kingdon
No abstract text is available yet for this article.
December 2015: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/26488686/cognitive-behavioural-therapy-brief-versus-standard-duration-for-schizophrenia
#16
REVIEW
Farooq Naeem, Saeed Farooq, David Kingdon
BACKGROUND: Cognitive behavioural therapy for people with schizophrenia is a psychotherapeutic approach that establishes links between thoughts, emotions and behaviours and challenges dysfunctional thoughts. There is some evidence to suggest that cognitive behavioural therapy for people with psychosis (CBTp) might be an effective treatment for people with schizophrenia. There are however, limitations in its provision due to available resource and training issues. One way to tackle this issue might be to offer a brief version of CBTp...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26360083/effects-of-cognitive-behaviour-therapy-for-worry-on-persecutory-delusions-in-patients-with-psychosis-wit-a-parallel-single-blind-randomised-controlled-trial-with-a-mediation-analysis
#17
RANDOMIZED CONTROLLED TRIAL
Daniel Freeman, Graham Dunn, Helen Startup, Katherine Pugh, Jacinta Cordwell, Helen Mander, Emma Černis, Gail Wingham, Katherine Shirvell, David Kingdon
BACKGROUND: Worry might be a contributory causal factor in the occurrence of persecutory delusions in patients with psychotic disorders. Therefore we postulated that reducing worry with cognitive behaviour therapy (CBT) would reduce persecutory delusions. METHODS: For our two-arm, assessor-blinded, randomised controlled trial (Worry Intervention Trial [WIT]), we recruited patients aged 18-65 years with persistent persecutory delusions but non-affective psychosis from two centres: the Oxford Health National Health Service (NHS) Foundation Trust (Oxford, UK) and the Southern Health NHS Foundation Trust (Southampton, UK)...
April 2015: Lancet Psychiatry
https://www.readbyqxmd.com/read/26301705/the-perseverative-thinking-questionnaire-in-patients-with-persecutory-delusions
#18
Emma Černis, Graham Dunn, Helen Startup, David Kingdon, Gail Wingham, Nicole Evans, Rachel Lister, Katherine Pugh, Jacinta Cordwell, Helen Mander, Daniel Freeman
BACKGROUND: Ruminative negative thinking has typically been considered as a factor maintaining common emotional disorders and has recently been shown to maintain persecutory delusions in psychosis. The Perseverative Thinking Questionnaire (PTQ) (Ehring et al., 2011) is a transdiagnostic measure of ruminative negative thinking that shows promise as a "content-free" measure of ruminative negative thinking. AIMS: The PTQ has not previously been studied in a psychosis patient group...
July 2016: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/26278784/the-effectiveness-of-a-patient-centred-assessment-with-a-solution-focused-approach-dialog-for-patients-with-psychosis-a-pragmatic-cluster-randomised-controlled-trial-in-community-care
#19
RANDOMIZED CONTROLLED TRIAL
Stefan Priebe, Lauren Kelley, Serif Omer, Eoin Golden, Sophie Walsh, Husnara Khanom, David Kingdon, Clare Rutterford, Paul McCrone, Rosemarie McCabe
BACKGROUND: DIALOG+ was developed as a computer-mediated intervention, consisting of a structured assessment of patients' concerns combined with a solution-focused approach to initiate change. This study tested the effectiveness of DIALOG+ in the community treatment of patients with psychosis. METHOD: This was a pragmatic, exploratory, parallel-group, cluster-randomised controlled trial. Clinicians within community teams - along with patients with psychosis under their care - were randomised to use DIALOG+ once per month for 6 months or an active control...
2015: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/26270489/can-cognitive-behaviour-therapy-beneficially-influence-arousal-mechanisms-in-psychosis
#20
Fleur M Howells, David S Baldwin, David G Kingdon
Cognitive behavioural therapy for psychosis (CBTp) is an approved adjunct therapy for patients with psychotic disorders; however, we do not fully understand the neurobiological effects that this therapy may exert. Arousal, as measured by electroencephalography (EEG), provides a useful electrophysiological marker for assessing psychotic disorders. EEG studies may therefore serve as a useful measure for assessing the underlying effects of CBTp in psychotic disorders.
January 2016: Human Psychopharmacology
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