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JOURNAL ARTICLE
Dora J Melber, Zachary T Berman, Marni B Jacobs, Andrew C Picel, Charlotte L Conturie, Kathy Zhang-Rutledge, Pratibha S Binder, Ramez N Eskander, Anne C Roberts, Michael T McHale, Gladys A Ramos, Jerasimos Ballas, Thomas F Kelly
BACKGROUND: Multidisciplinary care of placenta accreta spectrum cases improves pregnancy outcomes, but the specific components of such a multidisciplinary collaboration varies between institutions. As experience with placenta accreta spectrum increases, it is crucial to assess new surgical techniques and protocols to help improve maternal outcomes and to advocate for hospital resources. OBJECTIVE: This study aimed to assess a novel multidisciplinary protocol for the treatment of placenta accreta spectrum that comprises cesarean delivery, multivessel uterine embolization, and hysterectomy in a single procedure within a hybrid operative suite...
October 2021: American Journal of Obstetrics and Gynecology
#22
JOURNAL ARTICLE
Sherif A Shazly, Ismet Hortu, Jin-Chung Shih, Rauf Melekoglu, Shangrong Fan, Farhat Ul Ain Ahmed, Erbil Karaman, Ildar Fatkullin, Pedro V Pinto, Setyorini Irianti, Joel Noutakdie Tochie, Amr S Abdelbadie, Ahmet M Ergenoglu, Ahmet O Yeniel, Sermet Sagol, Ismail M Itil, Jessica Kang, Kuan-Ying Huang, Ercan Yilmaz, Yiheng Liang, Hijab Aziz, Tayyiba Akhter, Afshan Ambreen, Çağrı Ateş, Yasemin Karaman, Albir Khasanov, Fatkullina Larisa, Nariman Akhmadeev, Adelina Vatanina, Ana Paula Machado, Nuno Montenegro, Jusuf S Effendi, Dodi Suardi, Ahmad Y Pramatirta, Muhamad A Aziz, Amilia Siddiq, Ingrid Ofakem, Julius Sama Dohbit, Mohamed S Fahmy, Mohamed A Anan
INTRODUCTION: Placenta accreta spectrum is a major obstetric disorder that is associated with significant morbidity and mortality. The objective of this study is to establish a prediction model of clinical outcomes in these women. MATERIALS AND METHODS: PAS-ID is an international multicenter study that comprises 11 centers from 9 countries. Women who were diagnosed with PAS and were managed in the recruiting centers between 1 January 2010 and 31 December 2019 were included...
July 7, 2021: Journal of Maternal-fetal & Neonatal Medicine
#23
REVIEW
Ajay Gandhi, Klaus Görlinger, Sukesh C Nair, Poonam M Kapoor, Anjan Trikha, Yatin Mehta, Anil Handoo, Anil Karlekar, Jyoti Kotwal, Joseph John, Shashikant Apte, Vijay Vohra, Gajendra Gupta, Aseem K Tiwari, Anjali Rani, Shweta A Singh
In a developing country like India, with limited resources and access to healthcare facilities, dealing with massive hemorrhage is a major challenge. This challenge gets compounded by pre-existing anemia, hemostatic disorders, and logistic issues of timely transfer of such patients from peripheral hospitals to centers with adequate resources and management expertise. Despite the awareness amongst healthcare providers regarding management modalities of bleeding patients, no uniform Patient Blood Management (PBM) or perioperative bleeding management protocols have been implemented in India, yet...
January 2021: Journal of Anaesthesiology, Clinical Pharmacology
#24
JOURNAL ARTICLE
Bahram Salmanian, Steven L Clark, Shiu-Ki R Hui, Sarah Detlefs, Soroush Aalipour, Nazlisadat Meshinchi Asl, Alireza A Shamshirsaz
OBJECTIVE: Massive transfusion protocols are widely implemented in obstetrical practice in case of severe hemorrhage; however, different recommendations exist regarding the appropriate ratios of blood product components to be transfused. We report our extensive experience with massive component transfusion in a referral center in which the standard massive transfusion protocol is modified by ongoing clinical and laboratory evaluation. STUDY DESIGN: A retrospective chart review of all patients who had massive transfusion protocol activation in a level 4 referral center for obstetrical practice was performed from January 2014 to January 2020...
January 2023: American Journal of Perinatology
#25
REVIEW
Jennifer Prittie
OBJECTIVE: To evaluate the current role of cryoprecipitate in human and canine transfusion medicine. DATA SOURCES: Human and veterinary scientific reviews and original studies found using PubMed and CAB Abstract search engines were reviewed. HUMAN DATA SYNTHESIS: In the human critical care setting, cryoprecipitate is predominantly used for fibrinogen replenishment in bleeding patients with acute traumatic coagulopathy. Other coagulopathic patient cohorts for whom cryoprecipitate is recommended include those undergoing cardiovascular or obstetric procedures or patients bleeding from advanced liver disease...
March 2021: Journal of Veterinary Emergency and Critical Care
#26
JOURNAL ARTICLE
Susanne Ångerman, Hetti Kirves, Jouni Nurmi
Objective: While prehospital blood transfusion (PHBT) for trauma patients has been established in many services, the literature on PHBT use for nontrauma patients is limited. We aimed to describe and compare nontrauma and trauma patients receiving PHBT who had similar hemodynamic triggers. Methods: We analyzed 3.5 years of registry data from a single prehospital critical care unit. The PHBT protocol included two packed red blood cell units and was later completed with two freeze-dried plasma units. The transfusion triggers were a strong clinical suspicion of massive hemorrhage and systolic blood pressure below 90 mmHg or absent radial pulse...
March 2022: Prehospital Emergency Care
#27
REVIEW
Joy L Hawkins
Peripartum hemorrhage is a leading cause of maternal morbidity and mortality. Anesthesiologists must be familiar with conditions associated with hemorrhage that are unique to labor and delivery and not seen elsewhere in their practice. Regardless of etiology, early recognition and timely treatment of obstetric hemorrhage is necessary to prevent significant blood loss. Massive transfusion protocols are crucial to successful resuscitation, and providers should also consider use of cell salvage, uterine artery embolization, and anti-fibrinolytics...
December 2020: Anesthesiology Clinics
#28
MULTICENTER STUDY
Whitley Hulse, Timothy M Bahr, David S Morris, Douglas S Richards, Sarah J Ilstrup, Robert D Christensen
BACKGROUND: Most low-risk obstetric patients do not have crossmatched blood available to treat unexpected postpartum hemorrhage. An emergency-release blood transfusion (ERBT) program is critical for hospitals with obstetrical services. We performed a retrospective analysis of obstetrical ERBTs administered in our multihospital system. DESIGN AND METHODS: We collected data from the past 8 years at all Intermountain Healthcare hospitals on every ERBT after postpartum hemorrhage; logging circumstances, number and type of transfused products, and outcomes...
July 2020: Transfusion
#29
JOURNAL ARTICLE
David S Morris, Maxwell A Braverman, Jessica Corean, John C Myers, Elly Xenakis, Kayla Ireland, Leslie Greebon, Sarah Ilstrup, Donald H Jenkins
BACKGROUND: Death from postpartum hemorrhage (PPH) remains a significant preventable problem worldwide. Cold-stored, low-titer, type-O whole blood (LTOWB) is increasingly being used for resuscitation of injured patients, but it is uncommon in PPH patients, and it is unclear what its role may be in this population. STUDY DESIGN AND METHODS: Brief report of the early experience of WB use for PPH in two institutions, one university hospital and one private hospital...
June 2020: Transfusion
#30
JOURNAL ARTICLE
Jieun Kang, Hye Sim Kim, Eun Bi Lee, Young Uh, Kyoung Hee Han, Eun Young Park, Hyang Ah Lee, Dae Ryong Kang, In Bai Chung, Seong Jin Choi
PURPOSE: Recently, obstetric massive transfusion protocols have shifted toward early intervention. This study aimed to develop a prediction model for transfusion of ≥5 units of packed red blood cells (PRBCs) during cesarean section in women with placenta previa. MATERIALS AND METHODS: We conducted a cohort study including 287 women with placenta previa who delivered between September 2011 and April 2018. Univariate and multivariate logistic regression analyses were used to test the association between clinical factors, ultrasound factors, and massive transfusion...
February 2020: Yonsei Medical Journal
#31
JOURNAL ARTICLE
Jeannie L Callum, Calvin H Yeh, Andrew Petrosoniak, Mark J McVey, Stephanie Cope, Troy Thompson, Victoria Chin, Keyvan Karkouti, Avery B Nathens, Kimmo Murto, Suzanne Beno, Jacob Pendergrast, Andrew McDonald, Russell MacDonald, Neill K J Adhikari, Asim Alam, Donald Arnold, Lee Barratt, Andrew Beckett, Sue Brenneman, Hina Razzaq Chaudhry, Allison Collins, Margaret Harvey, Jacinthe Lampron, Clarita Margarido, Amanda McFarlan, Barto Nascimento, Wendy Owens, Menaka Pai, Sandro Rizoli, Theodora Ruijs, Robert Skeate, Teresa Skelton, Michelle Sholzberg, Kelly Syer, Jami-Lynn Viveiros, Josee Theriault, Alan Tinmouth, Rardi Van Heest, Susan White, Michelle Zeller, Katerina Pavenski
BACKGROUND: A massive hemorrhage protocol (MHP) enables rapid delivery of blood components in a patient who is exsanguinating pending definitive hemorrhage control, but there is variability in MHP implementation rates, content and compliance owing to challenges presented by infrequent activation, variable team performance and patient acuity. The goal of this project was to identify the key evidence-based principles and quality indicators required to develop a standardized regional MHP...
July 2019: CMAJ Open
#32
Timothy M Bahr, Tara L DuPont, David S Morris, Spencer E Pierson, Michael Sean Esplin, Samuel M Brown, Elizabeth A O'Brien, Sarah J Ilstrup, Robert D Christensen
BACKGROUND: In cases of massive hemorrhage in the US military, improved outcomes have been reported with the use of warm, fresh whole blood transfusions. Cold-stored low-titer type O whole blood (LTOWB) has become the preferred product for resuscitation of severe bleeding in deployed surgical units. Reports of LTOWB use in civilian trauma are becoming more frequent. CASE REPORT: We report our experience with emergency transfusion of LTOWB for a woman with massive postpartum hemorrhage...
October 2019: Transfusion
#33
JOURNAL ARTICLE
Rami A Ballout, Rayan Ghanem, Anwar Nassar, Ali H Hallal, Labib M Ghulmiyyah
This is the case of a 38 year-old Lebanese woman G2P1, history of previous cesarean section, presenting at 30+5 weeks of gestation with acute left-sided flank pain and a two-day history of chills and dysuria. In light of the clinical presentation, the patient was initially diagnosed with pyelonephritis and managed accordingly; however, her clinical status deteriorated with worsening hypotension and lethargy despite resuscitative measures and a normal abdominal ultrasound. Failure to revive the patient eventually led to a cardiac arrest for which a peri-mortem cesarean section was performed at bedside...
2019: Journal of women's health and development
#34
JOURNAL ARTICLE
Christian Horazeck, Christy J Crockett
A 31-year-old primigravid parturient with no pertinent medical history was admitted at 40 weeks and 4 days of gestation for postdate induction of labor. She was subsequently diagnosed with preeclampsia and developed hemolysis, elevated liver enzymes, and a low platelet count. An emergency cesarean delivery ensued owing to fetal bradycardia. Massive hemorrhage occurred on incision, and a diagnosis of ruptured subcapsular hepatic hematoma was made. The hemorrhage was managed using our institution's massive transfusion protocol...
June 3, 2019: A&A Practice
#35
JOURNAL ARTICLE
Jonathan Stanleigh, Jennia Michaeli, Shunit Armon, Fayez Khatib, Boris Zuckerman, Michael Shaya, Alexander Ioscovitch, Ofer Shenfeld, Dvora Greenblat, Rivka Farkash, Ahron Tevet, Arnon Samueloff, Sorina Grisaru Granovsky
BACKGROUND: Adherent and invasive placenta, termed Placenta Creta Spectrum (PCS), is associated with increased maternal morbidity and mortality. Incidence and risk factors for Placenta Creta are on the rise and call to optimize the obstetric care for this condition. OBJECTIVES: We sought to compare maternal and neonatal outcomes between a ProActive Peripartum Multidisciplinary Approach (PAMA) as compared to the urgent management of the Placenta Creta Spectrum patients...
June 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology
#36
JOURNAL ARTICLE
Reggie R Thomasson, Mark H Yazer, James D Gorham, Nancy M Dunbar
BACKGROUND: Massive transfusion protocols (MTPs) provide blood products rapidly and in fixed amounts. MTPs are commonly used in trauma but may also be used in other clinical settings, although evidence to support fixed-ratio resuscitation in nontraumatic hemorrhage is lacking. The goals of this study were to describe the types and contents of available MTPs and the clinical indications for MTP activation. METHODS: A survey was distributed to 353 transfusion medicine specialists to assess the types and contents of available MTPs...
May 2019: Transfusion
#37
JOURNAL ARTICLE
Christian Horazeck, Christy J Crockett
A 31-year-old primigravid parturient with no pertinent medical history was admitted at 40 weeks and 4 days of gestation for postdate induction of labor. She was subsequently diagnosed with preeclampsia and developed hemolysis, elevated liver enzymes, and a low platelet count. An emergency cesarean delivery ensued owing to fetal bradycardia. Massive hemorrhage occurred on incision, and a diagnosis of ruptured subcapsular hepatic hematoma was made. The hemorrhage was managed using our institution's massive transfusion protocol...
December 19, 2018: A&A Practice
#38
JOURNAL ARTICLE
C Margarido, J Ferns, V Chin, T Ribeiro, B Nascimento, J Barrett, E Herer, S Halpern, L Andrews, G Ballatyne, M Chapmam, J Gomes, J Callum
BACKGROUND: A structured approach to hemorrhagic emergencies in obstetrics has gained popularity with the implementation of massive hemorrhage protocols. The trauma literature suggests that routine quality reviews should be in place to improve patient outcomes. The aim of this study was to develop quality indicators and assess compliance by the clinical team. METHODS: A multidisciplinary team set the institutional quality indicators for the massive hemorrhage protocol review...
May 2019: International Journal of Obstetric Anesthesia
#39
JOURNAL ARTICLE
(no author information available yet)
Placenta accreta spectrum, formerly known as morbidly adherent placenta, refers to the range of pathologic adherence of the placenta, including placenta increta, placenta percreta, and placenta accreta. The most favored hypothesis regarding the etiology of placenta accreta spectrum is that a defect of the endometrial-myometrial interface leads to a failure of normal decidualization in the area of a uterine scar, which allows abnormally deep placental anchoring villi and trophoblast infiltration. Maternal morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion...
December 2018: Obstetrics and Gynecology
#40
JOURNAL ARTICLE
(no author information available yet)
Placenta accreta spectrum, formerly known as morbidly adherent placenta, refers to the range of pathologic adherence of the placenta, including placenta increta, placenta percreta, and placenta accreta. The most favored hypothesis regarding the etiology of placenta accreta spectrum is that a defect of the endometrial-myometrial interface leads to a failure of normal decidualization in the area of a uterine scar, which allows abnormally deep placental anchoring villi and trophoblast infiltration. Maternal morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion...
December 2018: Obstetrics and Gynecology
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