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Pesticide exposure

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https://www.readbyqxmd.com/read/28822925/accumulation-of-anticoagulant-rodenticides-chlorophacinone-bromadiolone-and-brodifacoum-in-a-non-target-invertebrate-the-slug-deroceras-reticulatum
#1
Hussein Alomar, André Chabert, Michael Coeurdassier, Danièle Vey, Philippe Berny
Anticoagulant rodenticides (ARs) are used worldwide to control populations of agricultural and urban rodents, but these pesticides may be accumulated in and poisoned non-target species of wildlife. Slugs may feed on rodenticide bait following field applications. Thus, it can be assumed that their predators are exposed to rodenticides through food chain transfer. However, AR exposure in the slugs has not been systematically studied. We investigated the accumulation of three ARs (chlorophacinone, bromadiolone or brodifacoum) in the slug Deroceras reticulatum exposed for a period of 5days followed by depuration time of 4days in the laboratory...
August 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822923/sequential-exposure-to-low-levels-of-pesticides-and-temperature-stress-increase-toxicological-sensitivity-of-crustaceans
#2
Renato Russo, Jeremias Martin Becker, Matthias Liess
Frequent pesticide-related impacts on ecosystems at concentrations considered environmentally safe indicate that the current risk assessment framework for registration of pesticides is not protective enough. Causes may include difficulties in assessing the effects of sequential pesticide pulses and their interaction with environmental stressors. By contrast to such realistic scenarios, risk assessment for registration of pesticides is typically based on tests of a single exposure period under benign laboratory conditions...
August 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822773/methodology-design-of-the-regional-sub-saharan-africa-total-diet-study-in-benin-cameroon-mali-and-nigeria
#3
Luc Ingenbleek, Eric Jazet, Anaclet D Dzossa, Samson B Adebayo, Julius Ogungbangbe, Sylvestre Dansou, Zima J Diallo, Christiant Kouebou, Abimbola Adegboye, Epiphane Hossou, Salimata Coulibaly, Sara Eyangoh, Bruno Le Bizec, Philippe Verger, Jean Kamanzi, Caroline Merten, Jean-Charles Leblanc
The core food model was described more than three decades ago, and has been used ever since to identify main food contributors to dietary intakes for both nutrients and other food chemicals. The Sub-Saharan Africa Total Diet Study (SSA-TDS) uses this model to describe the food consumption habits of some selected populations of Benin, Cameroon, Mali, and Nigeria, prior to use in the completion of quantitative risk assessments with regard to food chemicals. Food consumption data were derived from food expenditure data contained in national household budget surveys that were provided by the national institutes of statistics in each country...
August 16, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28819888/paraquat-induced-movement-disorder-in-relation-to-oxidative-stress-mediated-neurodegeneration-in-the-brain-of-drosophila-melanogaster
#4
S Niveditha, S R Ramesh, T Shivanandappa
Exposure to pesticides like paraquat (PQ) is considered as a risk factor for Parkinson's disease (PD). PQ has been shown to induce PD-like phenotype in experimental animals. Drosophila, a valuable laboratory model organism, is widely used to study neurodegenerative disorders including PD. The acute (single dose) PQ model of PD in Drosophila is associated with high mortality as well as reversibility of locomotor deficits and, therefore, does not replicate the disease phenotype. We have investigated the relevance of the acute and multiple (sublethal) dose of PQ to induce PD-like symptoms in Drosophila and shown that multiple-dose of PQ induces irreversible locomotor impairment without significant mortality...
August 18, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28819220/nosema-ceranae-fipronil-and-their-combination-compromise-honey-bee-reproduction-via-changes-in-male-physiology
#5
Guillaume Kairo, David G Biron, Faten Ben Abdelkader, Marc Bonnet, Sylvie Tchamitchian, Marianne Cousin, Claudia Dussaubat, Boris Benoit, André Kretzschmar, Luc P Belzunces, Jean-Luc Brunet
The honey bee is threatened by biological agents and pesticides that can act in combination to induce synergistic effects on its physiology and lifespan. The synergistic effects of a parasite/pesticide combination have been demonstrated on workers and queens, but no studies have been performed on drones despite their essential contribution to colony sustainability by providing semen diversity and quality. The effects of the Nosema ceranae/fipronil combination on the life traits and physiology of mature drones were examined following exposure under semi-field conditions...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818044/effects-of-the-vertically-transmitted-microsporidian-facilispora-margolisi-and-the-parasiticide-emamectin-benzoate-on-salmon-lice-lepeophtheirus-salmonis
#6
Jordan D Poley, Ben J G Sutherland, Mark D Fast, Ben F Koop, Simon R M Jones
BACKGROUND: Microsporidia are highly specialized, parasitic fungi that infect a wide range of eukaryotic hosts from all major taxa. Infections cause a variety of damaging effects on host physiology from increased stress to death. The microsporidian Facilispora margolisi infects the Pacific salmon louse (Lepeophtheirus salmonis oncorhynchi), an economically and ecologically important ectoparasitic copepod that can impact wild and cultured salmonids. RESULTS: Vertical transmission of F...
August 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28817615/genotoxic-effects-of-roundup-full-ii%C3%A2-on-lymphocytes-of-chaetophractus-villosus-xenarthra-mammalia-in-vitro-studies
#7
Juan Pablo Luaces, Luis Francisco Rossi, Mónica Gabriela Chirino, Melanie Browne, María Susana Merani, Marta Dolores Mudry
In Argentina, Chaetophractus villosus has a wide distribution that overlaps with agricultural areas where soybean is the predominant crop. In such areas the pesticide Roundup Full II® (RU) is widely applied. The genotoxic effect of its active ingredient glyphosate (RU is 66.2% glyphosate) on the peripheral blood lymphocytes of C. villosus was tested over a range of concentrations (280, 420, 560, 1120 μmol/L). Culture medium without glyphosate served as negative control, while medium containing mitomycin C served as positive control...
2017: PloS One
https://www.readbyqxmd.com/read/28815868/conceptual-considerations-on-exposure-assessment-goals-for-aquatic-pesticide-risks-at-eu-level
#8
Jos J T I Boesten
BACKGROUND: The assessment of the risk to aquatic organisms is an important aspect of pesticide registration. This assessment has to be based on well-defined exposure assessment goals (EAGs). However, these goals have not yet been defined for the EU authorisation procedure. RESULTS: The definition of an aquatic EAG consists of seven elements including the type of water body, the spatial dimension of this body, the spatial population of water bodies, the multi-year temporal population of concentrations for a single water body, and the space-time percentile combination to be selected from the spatio-temporal population of concentrations...
August 16, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28812286/occupational-exposures-and-health-outcomes-among-immigrants-in-the-usa
#9
REVIEW
Sally C Moyce, Marc Schenker
PURPOSE OF REVIEW: Immigrants experience higher rates of occupational injury and fatality than their native-born counterparts. This review summarizes the current data related to occupational/environmental exposures and explores potential reasons for the disparities. RECENT FINDINGS: Immigrant workers are employed in sectors that expose them to dangerous working conditions. They experience increased risk for exposure to heat, pesticides, hazardous chemicals, and cleaning agents, as well as physical hazards such as falls...
August 15, 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28811173/prenatal-exposure-to-pyrethroid-pesticides-and-childhood-behavior-and-executive-functioning
#10
Melissa A Furlong, Dana Boyd Barr, Mary S Wolff, Stephanie M Engel
Several previous studies of pyrethroid biomarkers and behavior have reported associations between concurrent pyrethroid levels and adverse behavioral problems in children. One geospatial study reported associations between prenatal exposure to pyrethroids and autism. However, the association between prenatal pyrethroid biomarkers and childhood behavior is unknown. The Mount Sinai Children's Environmental Health Center is a prospective birth cohort with urinary pyrethroid biomarkers during pregnancy and behavioral measurements at 4, 6, and 7-9 years of age...
August 12, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28810201/the-association-between-non-hodgkin-lymphoma-and-organophosphate-pesticides-exposure-a-meta-analysis
#11
REVIEW
Liqin Hu, Dan Luo, Tingting Zhou, Yun Tao, Jingwen Feng, Surong Mei
Several epidemiological studies show the association between organophosphate pesticides (OPs) and the risk of non-Hodgkin lymphoma (NHL), yet various research results remain controversial. To explore the hazard of OPs exposure to human health, three kinds of OPs (Terbufos, Malathion, and Diazinon) that are non-halogenated aliphatic compounds were included in the meta-analysis. We searched PubMed and Web of Science Databases for articles published from 1985 to February 2017. The databases were also searched for eligible studies through a manual references search...
August 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28808317/bumblebee-colony-development-following-chronic-exposure-to-field-realistic-levels-of-the-neonicotinoid-pesticide-thiamethoxam-under-laboratory-conditions
#12
Dara A Stanley, Nigel E Raine
Neonicotinoid pesticides are used in agriculture to reduce damage from crop pests. However, beneficial insects such as bees can come into contact with these pesticides when foraging in treated areas, with potential consequences for bee declines and pollination service delivery. Honeybees are typically used as a model organism to investigate insecticide impacts on bees, but relatively little is known about impacts on other taxa such as bumblebees. In this experiment, we chronically exposed whole mature bumblebee (Bombus terrestris) colonies to field-realistic levels of the neonicotinoid thiamethoxam (2...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28806556/persistent-organic-pollutants-in-fat-of-three-species-of-pacific-pelagic-longline-caught-sea-turtles-accumulation-in-relation-to-ingested-plastic-marine-debris
#13
Katharine E Clukey, Christopher A Lepczyk, George H Balazs, Thierry M Work, Qing X Li, Melannie J Bachman, Jennifer M Lynch
In addition to eating contaminated prey, sea turtles may be exposed to persistent organic pollutants (POPs) from ingesting plastic debris that has absorbed these chemicals. Given the limited knowledge about POPs in pelagic sea turtles and how plastic ingestion influences POP exposure, our objectives were to: 1) provide baseline contaminant levels of three species of pelagic Pacific sea turtles; and 2) assess trends of contaminant levels in relation to species, sex, length, body condition and capture location...
August 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28803741/the-cardiovascular-toxicity-of-triadimefon-in-early-life-stage-of-zebrafish-and-potential-implications-to-human-health
#14
Hong-Cui Liu, Tian-Yi Chu, Li-Li Chen, Wen-Jun Gui, Guo-Nian Zhu
The health risk of triadimefon (TF) to cardiovascular system of human is still unclear, especially to pesticide suicides population, occupational population (farmers, retailers and pharmaceutical workers), and special population (young children and infants, pregnant women, older people, and those with compromised immune systems) who are at a greater risk. Therefore, firstly we explored the toxic effects and possible mechanism of cardiovascular toxicity induced by TF using zebrafish model. Zebrafish at stage of 48 h post fertilization (hpf) exposed to TF for 24 h exhibited morphological malformations which were further confirmed by histopathologic examination, including pericardial edema, circulation abnormalities, serious venous thrombosis and increased distance between the sinus venosus (SV) and bulbus arteriosus (BA) regions of the heart...
August 10, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28802893/complex-mixtures-of-dissolved-pesticides-show-potential-aquatic-toxicity-in-a-synoptic-study-of-midwestern-u-s-streams
#15
Lisa H Nowell, Patrick W Moran, Travis S Schmidt, Julia E Norman, Naomi Nakagaki, Megan E Shoda, Barbara J Mahler, Peter C Van Metre, Wesley W Stone, Mark W Sandstrom, Michelle L Hladik
Aquatic organisms in streams are exposed to pesticide mixtures that vary in composition over time in response to changes in flow conditions, pesticide inputs to the stream, and pesticide fate and degradation within the stream. To characterize mixtures of dissolved-phase pesticides and degradates in Midwestern streams, a synoptic study was conducted at 100 streams during May-August 2013. In weekly water samples, 94 pesticides and 89 degradates were detected, with a median of 25 compounds detected per sample and 54 detected per site...
August 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28802169/human-health-risk-assessment-on-the-consumption-of-fruits-and-vegetables-containing-residual-pesticides-a-cancer-and-non-cancer-risk-benefit-perspective
#16
Mathieu Valcke, Marie-Hélène Bourgault, Louis Rochette, Louise Normandin, Onil Samuel, Denis Belleville, Carole Blanchet, Denise Phaneuf
Pesticide residues in food is a public health concern. This study aimed to evaluate health risk and benefit associated with chronic consumption of fruits and vegetables (F&V) containing residual pesticides in the province of Quebec, Canada. Based on a representative sample of Quebecers (n=4727, aged 1-79) enrolled in the Canadian nutrition survey, population's mean chronic dietary exposure through consumption of F&V was evaluated for 169 different pesticide active ingredients (PAI), including 135 for which toxicological reference values (TRV) were available in the literature...
August 9, 2017: Environment International
https://www.readbyqxmd.com/read/28802014/flow-covariate-prediction-of-stream-pesticide-concentrations
#17
Paul L Mosquin, Jeremy Aldworth, Wenlin Chen
Potential "peak" functions (e.g., maximum rolling averages over a given duration) of annual pesticide concentrations in the aquatic environment are important exposure parameters (or target quantities) for ecological risk assessments. These target quantities require accurate concentration estimates on non-sampled days in a monitoring program. In this paper, we examine stream flow as a covariate via universal kriging to improve predictions of maximum m-day (m = 1, 7, 14, 30, 60) rolling averages and the 95(th) percentiles of atrazine concentration in streams where data were collected every 7 or 14 days...
August 12, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28799488/environment-and-neurodegenerative-diseases-an-update-on-mirna-role
#18
Margherita Ferrante, Gea Oliveri Conti
INTRODUCTION: The importance of neurodegenerative diseases on the management of public health is growing and the real role of the environment and miRNA in their occurrence is still unclear. miRNA can affect significantly the regulatory network. The complex variety and gene-regulatory capacity of miRNAs is particularly valuable in the brain, being a very complex organ with a functional specialization of neurons highly adaptable to environmental stimuli. In particular a miRNAs role is demonstrated in neurological diseases as the effect to toxic and mutagenic substances exposure by the environment...
August 11, 2017: MicroRNA
https://www.readbyqxmd.com/read/28796631/endocrine-disruption-in-human-fetal-testis-explants-by-individual-and-combined-exposures-to-selected-pharmaceuticals-pesticides-and-environmental-pollutants
#19
Pierre Gaudriault, Séverine Mazaud-Guittot, Vincent Lavoué, Isabelle Coiffec, Laurianne Lesné, Nathalie Dejucq-Rainsford, Martin Scholze, Andreas Kortenkamp, Bernard Jégou
BACKGROUND: Numerous chemicals are capable of disrupting androgen production, but the possibility that they might act together to produce effects greater than those of the most effective component in the mixture has not been studied directly in human tissues. Suppression of androgen synthesis in fetal life has been associated with testis maldescent, malformations of the genitalia at birth, and poor semen quality later in life. OBJECTIVES: Our aim was to investigate whether chemicals can act together to disrupt androgen production in human fetal testis explants and to evaluate the importance of mixture effects when characterizing the hazard of individual chemicals...
August 4, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28782715/corticosterone-potentiates-dfp-induced-neuroinflammation-and-affects-high-order-diffusion-imaging-in-a-rat-model-of-gulf-war-illness
#20
Bang-Bon Koo, Lindsay T Michalovicz, Samanthan Calderazzo, Kimberly A Kelly, Kimberly Sullivan, Ronald J Killiany, James P O'Callaghan
Veterans of the 1991 Gulf War were potentially exposed to a variety of toxic chemicals, including sarin nerve agent and pesticides, which have been suspected to be involved in the development of Gulf War Illness (GWI). Several of these exposures cause a neuroinflammatory response in mice, which may serve as a basis for the sickness behavior-like symptoms seen in veterans with GWI. Furthermore, conditions mimicking the physiological stress experienced during the war can exacerbate this effect. While neuroinflammation has been observed post-exposure using animal models, it remains a challenge to evaluate neuroinflammation and its associated cellular and molecular changes in vivo in veterans with GWI...
August 4, 2017: Brain, Behavior, and Immunity
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