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Pesticide exposure

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https://www.readbyqxmd.com/read/29673448/case-control-study-of-impulsivity-aggression-pesticide-exposure-and-suicide-attempts-using-pesticides-among-farmers
#1
Chun Ping Lyu, Jian Ru Pei, L Cheryl Beseler, Yu Ling Li, Jian Hui Li, Ming Ren, Lorann Stallones, Shu Ping Ren
A case-control study was conducted to investigate associations between organophosphate pesticide (OP) exposure, aggression, impulsivity, and attempted suicide. Questionnaires were used to collect information; impulsivity and aggression were measured by the Barratt Impulsivity Scale (BIS) and the Aggression Inventory (AI). A greater number of OP symptoms was associated with an increased odds of a suicide attempt after adjusting for marital status and income (OR = 1.45; CI 1.14-1.86). Attempted suicide was significantly associated with high impulsivity scores (means: 72...
March 2018: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/29671119/potential-risks-of-dietary-exposure-to-chlorpyrifos-and-cypermethrin-from-their-use-in-fruit-vegetable-crops-and-beef-cattle-productions
#2
Daniela M Ferré, Arnoldo A M Quero, Antonio F Hernández, Valentina Hynes, Marcelo J Tornello, Carlos Lüders, Nora B M Gorla
The active ingredients (a.i.) used as pesticides vary across regions. Diet represents the main source of chronic exposure to these chemicals. The aim of this study was to look at the pesticides applied in fruit, vegetable, and beef cattle productions in Mendoza (Argentina), to identify those that were simultaneously used by the three production systems. Local individuals (n = 160), involved in these productions, were interviewed. Glyphosate was the a.i. most often used by fruit-vegetable producers, and ivermectin by beef cattle producers...
April 18, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29671087/severe-adverse-reactions-following-ketoconazole-fluconazole-and-environmental-exposures-a-case-report
#3
Allan Lieberman, Luke Curtis
In this case report, we describe a 66-year-old man who developed multiple adverse reactions beginning at age 56 after exposure to several azole antifungal drugs including ketoconazole and fluconazole. He also had a history of more than 40 years exposure to chemicals including pesticides, wood preservatives, fertilizers, and welding chemicals. His reactions involved dehydration (requiring several liters of intravenous fluids in less than an hour to alleviate this condition), angioedema, nausea, tinnitus, hypotension, and difficulty breathing...
April 18, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29669110/chronic-occupational-exposure-endured-by-tobacco-farmers-from-brazil-and-association-with-dna-damage
#4
Vívian F Silva Kahl, Varinderpal Singh Dhillon, Daniel Simon, Fernanda Rabaioli da Silva, Mirian Salvador, Cátia Dos Santos Branco, Mónica Cappetta, Wilner Martínez-López, Flávia V Thiesen, Johnny F Dias, Claudia Telles de Souza, Michael Fenech, Juliana da Silva
Tobacco farming is an important economic income in Brazil, although it has been challenged as regard the occupational exposure to both pesticides and nicotine endured by farmers. Chronic occupational exposure to complex mixtures can lead to health hazardous. We examined genomic instability and epigenetic changes in tobacco farmers occupationally exposed to pesticide mixtures and nicotine at tobacco fields. DNA damage was assessed by alkaline comet assay in blood cells. Genomic DNA was isolated, and telomere length was measured using quantitative polymerase chain reaction assay...
April 13, 2018: Mutagenesis
https://www.readbyqxmd.com/read/29667781/ameliorative-effect-of-nanoencapsulated-flavonoid-against-chlorpyrifos-induced-hepatic-oxidative-damage-and-immunotoxicity-in-wistar-rats
#5
Sanvidhan G Suke, Prasad Sherekar, Vivek Kahale, Shaktipal Patil, Dharmendra Mundhada, Vivek M Nanoti
The theme of the present work is to evaluate the protective effect of nanoencapsulated quercetin (NEQ) against chlorpyrifos (CPF)-induced hepatic damage and immune alterations in animals. Nanoparticles (NP) drug encapsulation was prepared. Forty male Wistar rats were divided into eight groups. Two groups served as control and CPF (13.5 mg/kg) treatment for 28 days. Other three groups were free quercetin (QC), NP and NEQ treated with 3 mg/kg respectively for 15 days; whereas remaining three groups received treatment of CPF and QC, NP, NEQ, respectively, for 15 days...
April 18, 2018: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/29665533/the-effect-of-antibiotics-on-the-persistence-of-herbicides-in-soil-under-the-combined-pollution
#6
Wenqi Jiang, Jing Gao, Zheng Cheng, Peng Wang, Zhiqiang Zhou, Donghui Liu
Antibiotic contamination in agricultural lands through manure application causes changes in soil enzyme activity and the abundance of microbes, which may affect the fate of agrochemicals. A clear understanding of antibiotic-pesticide interactions is very limited. The objective of this study was to investigate the effect of oxytetracycline (OTC) on the persistence of triazine and chloroacetanilide herbicides in soil under a combined application scenario. Soil enzyme activity and the abundance of soil microbes disturbed by OTC were measured...
April 10, 2018: Chemosphere
https://www.readbyqxmd.com/read/29662130/application-of-improved-approach-to-evaluate-a-community-intervention-to-reduce-exposure-of-young-children-living-in-farmworker-households-to-organophosphate-pesticides
#7
William C Griffith, Eric M Vigoren, Marissa N Smith, Tomomi Workman, Beti Thompson, Gloria D Coronado, Elaine M Faustman
The take-home pathway is a significant source of organophosphate pesticide exposure for young children (3-5 years old) living with an adult farmworker. This avoidable exposure pathway is an important target for intervention. We selected 24 agricultural communities in the Yakima Valley of Washington State and randomly assigned them to receive an educational intervention (n = 12) to reduce children's pesticide exposure or usual care (n = 12). We assessed exposure to pesticides in nearly 200 adults and children during the pre and post-intervention periods by measuring metabolites in urine...
April 17, 2018: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29660695/metabolite-profiles-of-striped-marsh-frog-limnodynastes-peronii-larvae-exposed-to-the-anti-androgenic-fungicides-vinclozolin-and-propiconazole-are-consistent-with-altered-steroidogenesis-and-oxidative-stress
#8
Steven D Melvin, Frederic D L Leusch, Anthony R Carroll
Amphibians use wetlands in urban and agricultural landscapes for breeding, growth and development. Fungicides and other pesticides used in these areas have therefore been identified as potential threats that could contribute towards amphibian population declines. However, relatively little is known about how such chemicals influence sensitive early life-stages or how short episodic exposures influence sub-lethal physiological and metabolic pathways. The present study applied untargeted metabolomics to evaluate effects in early post-hatch amphibian larvae exposed to the anti-androgenic fungicides vinclozolin and propiconazole...
April 11, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29660432/evaluation-of-hematological-and-biochemical-parameters-of-pesticide-retailers-following-occupational-exposure-to-a-mixture-of-pesticides
#9
Masoud Neghab, Hamed Jalilian, Shekoufeh Taheri, Mohsen Tatar, Zeynab Haji Zadeh
AIMS: Recently concern has been raised regarding possible health effects of exposure of pesticide retailers to chemicals they handle. Additionally, it is not known whether exposure to these compounds by retailers may be associated with any liver and kidney dysfunction or hematological abnormalities. This study was undertaken to address these issue. MAIN METHODS: In this cross-sectional study, 70 male pesticide retailers (cases) and 64 male subjects, randomly selected from the constructions workers of city council contractors, as the referent group, were investigated...
April 13, 2018: Life Sciences
https://www.readbyqxmd.com/read/29659907/effect-of-cold-storage-on-biological-traits-of-psix-saccharicola-hymenoptera-platygastridae-an-egg-parasitoid-of-acrosternum-arabicum-hemiptera-pentatomidae
#10
Farzane Forouzan, Mohammad Amin Jalali, Mahdi Ziaaddini, Hamid Hashemi Rad
Psix saccharicola (Mani) (Hymenoptera: Platygastridae) is a solitary egg parasitoid of the pistachio green stink bug, Acrosternum arabicum (Wagner) (Hemiptera: Pentatomidae), which is one of the most important pests of pistachio in Iran. Augmentation of P. saccharicola field populations using mass-reared individuals may provide an alternative to conventional pesticide use for pistachio green stink bug control. Cold storage is an important component of mass-rearing protocols for optimum timing of host egg parasitization and potentially extended storage of P...
April 5, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29659035/metabolomics-on-a-chip-approach-to-study-hepatotoxicity-of-ddt-permethrin-and-their-mixtures
#11
Rachid Jellali, Françoise Gilard, Vittoria Pandolfi, Audrey Legendre, Marie-José Fleury, Patrick Paullier, Cécile Legallais, Eric Leclerc
Despite the diversity of studies on pesticide toxicities, there is a serious lack of information concerning the toxic effect of pesticides mixtures. Dichlorodiphenyl-trichloroethane (DDT) and permethrin (PMT) are among the most prevalent pesticides in the environment and have been the subject of several toxicological studies. However, there are no data on the toxicity of their mixtures. In this study, we used an approach combining cell culture in microfluidic biochips with gas chromatography-mass spectrometry metabolomics profiling to investigate the biomarkers of toxicity of DDT, PMT and their mixtures...
April 16, 2018: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/29658108/maternal-residential-pesticide-use-and-risk-of-childhood-leukemia-in-costa-rica
#12
Carly Hyland, Robert B Gunier, Catherine Metayer, Michael N Bates, Catharina Wesseling, Ana M Mora
Evidence suggests that early-life exposure to pesticides inside the home may be associated with childhood leukemia, however data from Latin American countries are limited. We examined whether self-reported maternal residential pesticide use and nearby pesticide applications-before and after child's birth-were associated with acute lymphoblastic leukemia (ALL) in the Costa Rican Childhood Leukemia Study (CRCLS), a population-based case-control study (2001-2003). Cases (n=251 ALL) were diagnosed between 1995 and 2000 (age <15 years at diagnosis) and were identified through the Costa Rican Cancer Registry and National Children's Hospital...
April 15, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29656190/effect-of-titanium-dioxide-nanoparticles-on-the-bioavailability-and-neurotoxicity-of-cypermethrin-in-zebrafish-larvae
#13
Meng Li, Qiong Wu, Qiangwei Wang, Dandan Xiang, Guonian Zhu
In aquatic environment, the presence of nanoparticles (NPs) has been reported to modify the bioavailability and toxicity of the organic toxicants. Nevertheless, the combined toxicity of NPs and the pesticides that were used world-widely still remains unclear. Cypermethrin (CYP), a synthetic pyrethroid insecticide, is commonly used for controlling agricultural and indoor pests. Therefore, the effects of titanium dioxide NPs (nTiO2 ) on CYP bioconcentration and its effects on the neuronal development in zebrafish were investigated in our study...
March 31, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29656176/underreporting-of-fatal-poisonings-in-brazil-a-descriptive-study-using-data-from-four-information-systems
#14
Andrea Franco Amoras Magalhães, Eloisa Dutra Caldas
Poisoning is a worldwide problem that involves individuals of all ages and a range of chemicals. In this study, fatal poisoning cases that occurred in the Federal District of Brazil (DF) from 2009 to 2013 were described using information from four systems, and the reasons for underreporting of each system were discussed. Data were obtained from the mortality information system (SIM), the notifiable disease information system (SINAN), the poison information center (CIT), and the forensic medicine institute (IML) of the DF...
April 4, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29653138/neuroprotective-action-of-4-hydroxyisophthalic-acid-against-paraquat-induced-motor-impairment-involves-amelioration-of-mitochondrial-damage-and-neurodegeneration-in-drosophila
#15
Niveditha S, T Shivanandappa
Neurodegenerative disorders including Parkinson's disease (PD) are believed to be caused by oxidative stress and mitochondrial dysfunction. Exposure to environmental agents such as pesticides has been implicated in the etiology of sporadic PD. Paraquat (PQ), a widely used herbicide, induces PD symptoms in laboratory animals including Drosophila. PQ acts as a free radical generator and induces oxidative damage, which is implicated in neuronal cell death. Drosophila model of PQ-induced PD offers a convenient tool for mechanistic studies and, to assess the neuroprotective potential of natural antioxidants...
April 10, 2018: Neurotoxicology
https://www.readbyqxmd.com/read/29649189/acute-metam-sodium-poisoning-caused-by-occupational-exposure-at-a-flower-farm-uganda-october-2016
#16
Susan Nakubulwa, Joy Kusiima, Daniel Kadobera, Joan N Mutyoba, Alex R Ario, Bao-Ping Zhu
On October 25, 2016, media reports alerted the Uganda Ministry of Health to an outbreak of >80 cases of vomiting, syncope, and acute diarrhea among workers at a flower farm in central Uganda; 27 workers were hospitalized. On November 1, an investigation was undertaken by the Uganda Public Health Fellowship Program.* A case-control study found that working inside greenhouse 7, which had been fumigated with the organosulfur compound metam sodium the night of October 13, was strongly associated with illness...
April 13, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29644616/genetic-aberrations-of-the-k-ras-proto-oncogene-and-in-bladder-cancer-in-relation-to-pesticide-exposure
#17
Diaa A Hameed, Heba A Yassa, Michael N Agban, Randa T Hanna, Ahmed M Elderwy, Mohamed A Zwaita
In Egypt, bladder cancer is one of the most popular cancer, accounting for 31% of all cancer cases. It ranks first in males about 16.2% of male cancer. The incidence in rural areas among males is near 32 per 100,000. The exact etiology of bladder cancer is still unknown; K-ras gene is known as a critical DNA target for chemical carcinogens as a pesticide. Some occupational hazard exposure is thought to be directly genotoxic, while others might enhance the mutagenicity and carcinogenicity of directly acting genotoxic agents...
April 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29643573/beyond-polarization-using-q-methodology-to-explore-stakeholders-views-on-pesticide-use-and-related-risks-for-agricultural-workers-in-washington-state-s-tree-fruit-industry
#18
Nadine Lehrer, Gretchen Sneegas
Controversies in food and agriculture abound, with many portrayed as conflicts between polarized viewpoints. Framing such controversies as dichotomies, however, can at times obscure what might be a plurality of views and potential common ground on the subject. We used Q methodology to explore stakeholders' views about pesticide safety, agricultural worker exposure, and human health concerns in the tree fruit industry of central Washington State. Using a purposive sample of English and Spanish-speaking agricultural workers, industry representatives, state agencies, educators, and advocates (n = 41), participants sorted 45 statements on pesticide use and perceived human safety risks in the tree fruit industry in 2011...
January 2018: Agriculture and Human Values
https://www.readbyqxmd.com/read/29643175/impaired-associative-learning-after-chronic-exposure-to-pesticides-in-young-adult-honey-bees
#19
Carolina Mengoni Goñalons, Walter M Farina
Neonicotinoids are the most widespread insecticides in agriculture, preferred for their low toxicity to mammals and their systemic nature. Nevertheless, there have been increasing concerns regarding their impact on non-target organisms. Glyphosate is also widely used in crops and, therefore, traces of this pesticide are likely to be found together with neonicotinoids. Although glyphosate is considered a herbicide, adverse effects have been found on animal species, including honey bees. Apis mellifera is one of the most important pollinators in agroecosystems and is exposed to both these pesticides...
April 11, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29642657/exploring-demographic-and-environmental-factors-related-to-unintentional-pesticide-poisonings-in-children-and-adolescents-in-texas
#20
Amber Trueblood, Daikwon Han, Eva Shipp, Leslie Cizmas
There is limited literature on the frequency and distribution of pesticide exposures, specifically with respect to demographic and environmental factors in the United States. The purpose of this exploratory study was to investigate geographic trends and factors associated with unintentional pesticide exposures in children and adolescents in Texas. The study used an ecological design with secondary data. A spatial scan statistic, based on a Poisson regression model, was employed to identify spatial clusters of unintentional pesticide-related poison center exposures...
March 26, 2018: Environmental Health and Toxicology
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