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Pesticide exposure

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https://www.readbyqxmd.com/read/28724251/concurrent-exposures-to-nonylphenol-bisphenol-a-phthalates-and-organophosphate-pesticides-on-birth-outcomes-a-cohort-study-in-taipei-taiwan
#1
Yu-Fang Huang, Wen-Chi Pan, Yen-An Tsai, Chia-Huang Chang, Pei-Jung Chen, Yi-Shuan Shao, Ming-Song Tsai, Jia-Woei Hou, Chensheng Alex Lu, Mei-Lien Chen
Prenatal exposure to phenols, phthalates (PAEs), and organophosphate (OP) pesticides may increase the risk of abnormal birth outcomes. However, many previous studies have examined exposure to a limited number of chemical classes or exposure profiles limited to a specific stage of pregnancy. This study aims to characterize the concurrent exposure scenario throughout pregnancy by simultaneously monitoring internal doses of several endocrine-disrupting compounds (EDCs), including 2 phenols (nonylphenol (NP) and bisphenol A (BPA)), 9 PAEs, and 6 OP pesticide metabolites and to assess the relationships between concurrent exposure to EDCs and infant birth weight, length, and head and chest circumference...
July 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28724247/persistent-organic-pollutants-and-risk-of-diabetes-and-obesity-on-healthy-adults-results-from-a-cross-sectional-study-in-spain
#2
Luis Alberto Henríquez-Hernández, Octavio P Luzardo, Pilar F Valerón, Manuel Zumbado, Lluis Serra-Majem, María Camacho, Ana González-Antuña, Luis D Boada
Environmental exposure to persistent organic pollutants (POPs) has been reported to be relevant in the population of the Canary Islands (Spain), especially that of organochlorine pesticides. On the other hand, the population of this archipelago presents a high prevalence of type 2 diabetes (T2D), and it has been recently reported that environmental chemical contamination could play a role in the development of this disease. We performed a cross-sectional study in a representative sample from this archipelago to evaluate whether serum levels of selected POPs could be considered as risk factors for diabetes in this population...
July 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28723966/activated-carbon-a-useful-medium-to-bind-chlordecone-in-soil-and-limit-its-transfer-to-growing-goat-kids
#3
Sarah Yehya, Matthieu Delannoy, Agnès Fournier, Moomen Baroudi, Guido Rychen, Cyril Feidt
Chlordecone (Kepone) (CLD) is a highly persistent pesticide which was extensively used in the French West Indies; high levels of CLD can still currently be found in large agricultural areas. As CLD transfers from soil to animals mainly via involuntary ingestion, the consumption of foodstuffs derived from animals raised in contaminated areas may significantly contribute to exposure of humans to CLD. The present study was designed to test the efficacy of two different activated carbons (ACs) sources in limiting CLD transfer from soil to animal...
2017: PloS One
https://www.readbyqxmd.com/read/28721745/pesticide-genotoxicity-in-cotton-picking-women-in-pakistan-evaluated-using-comet-assay
#4
Tayyaba Ali, Muhammad Ismail, Farkhanda Asad, Asma Ashraf, Usman Waheed, Qaiser M Khan
To control agricultural pests and meet the increasing food demands, pesticides use has been increased substantially over time. Although pesticides are relatively specific to their targets, they can affect non-target organisms and are hazardous for the population around the application areas particularly to the individuals engaged in different types of agricultural activities. This situation is worse in developing and under-developed countries where personal protective equipment is merely used and regulatory guidelines are hardly practiced...
July 19, 2017: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/28721614/low-doses-of-chlorpyrifos-interfere-with-spermatogenesis-of-rats-through-reduction-of-sex-hormones
#5
Dinithi Champika Peiris, Thamali Dhanushka
Use of pesticides results in indirect effects on human health. We aimed to evaluate implications of toxicological effects of subchronic chlorpyrifos exposure on reproductive function in male rats. A total of 48 adult Wistar male rats were separated into four groups (n = 12). Animals were gavaged with 2.5 mg/kg (T1), 5 mg/kg (T2), or 10 mg/kg (T3) body weight of chlorpyrifos (CPF) or distilled water (control) daily for 30 days. Organ weights, epididymal sperm parameters, DNA integrity, sex hormonal (FHS and LH) levels, and alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), and creatinine concentrations were determined on day 31...
July 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28720696/persistent-organic-pollutants-impair-insulin-secretory-function-of-pancreatic-beta-cells-human-and-in-vitro-evidence
#6
Yu-Mi Lee, Chae-Myeong Ha, Se-A Kim, Themis Thoudam, Young-Ran Yoon, Dae-Jung Kim, Hyeon-Chang Kim, Hyo-Bang Moon, Sungmi Park, In-Kyu Lee, Duk-Hee Lee
Persistent organic pollutants (POPs), especially organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), have emerged as a new risk factor of type 2 diabetes (T2D). We evaluated whether chronic exposure to low-dose POPs affects insulin secretory function of beta-cells in humans and in vitro cells. Serum concentrations of OCPs and PCBs were measured in 200 nondiabetic adults. Mathematical-model-based insulin secretion indices were estimated using a 2-hour 7-sample oral glucose tolerance test. Insulin secretion by INS1E beta-cells was measured after 48-hour treatment with 3 OCPs or a PCB mixture...
July 18, 2017: Diabetes
https://www.readbyqxmd.com/read/28720389/exposure-to-pesticide-as-a-risk-factor-for-depression-a-population-based-longitudinal-study-in-korea
#7
Sang-Baek Koh, Tae Hui Kim, Seongho Min, Kyungsuk Lee, Dae Ryong Kang, Jung Ran Choi
BACKGROUND: Exposure to pesticides is associated with mental disorders, including depression, especially among occupationally exposed populations, such as farmers. The results of experimental studies ascribed the negative effects of pesticides on mental health to their neurotoxic and endocrine-disrupting activities. PURPOSE: This study aimed to investigate the association between the risk of depression and high- or low-level exposure to pesticides in a rural population...
July 15, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28719883/sublethal-insecticide-exposure-affects-reproduction-chemical-phenotype-as-well-as-offspring-development-and-antennae-symmetry-of-a-leaf-beetle
#8
Thorben Müller, Alexander Prosche, Caroline Müller
The area of agriculturally used land and following to that the use of pesticides are steadily increasing. Insecticides do not only reduce pest organisms on crops but can also affect non-target organisms when present in sublethal concentrations in the environment. We investigated the effects of an exposure to sublethal pyrethroid (lambda-cyhalothrin) concentrations, at doses 20 and 60 times lower than the LC50, respectively, on reproductive traits and adult cuticular hydrocarbon (CHC) profiles of a leaf beetle (Phaedon cochleariae Fabricius)...
July 15, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28718769/pesticide-exposure-and-risk-of-rheumatoid-arthritis-among-licensed-male-pesticide-applicators-in-the-agricultural-health-study
#9
Armando Meyer, Dale P Sandler, Laura E Beane Freeman, Jonathan N Hofmann, Christine G Parks
BACKGROUND: The occupation of farming has been associated with rheumatoid arthritis (RA); pesticides may account for this association, but there are few studies. OBJECTIVES: We investigated associations between RA and use of pesticides in the Agricultural Health Study. METHODS: The study sample was drawn from male pesticide applicators enrolled in 1993-1997 who provided questionnaire data at baseline and at least once during follow-up (over a median 18 y; interquartile range 16-19)...
July 14, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28718371/changes-in-the-expression-of-genes-involved-in-cell-cycle-regulation-and-the-relative-telomere-length-in-the-process-of-canceration-induced-by-omethoate
#10
Xiaoran Duan, Yongli Yang, Sihua Wang, Xiaolei Feng, Tuanwei Wang, Pengpeng Wang, Suxiang Liu, Lei Li, Wu Yao, Liuxin Cui, Wei Wang
Organophosphorous pesticides (OPs), with high efficiency, broad-spectrum and low residue, are widely used in China. Omethoate is a broad category of organophosphorous pesticides and is more domestically utilized which has chronic toxic effect on human health caused by long-term, low-dose exposure to Ops, recently its potential genotoxicity has attracted wide attention which can cause chromosomal DNA damage. Thus, the aim of this study is screen susceptible biomarkers and explore the mechanism of canceration induced by omethoate...
July 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28718019/neonatal-placental-and-umbilical-cord-blood-parameters-in-pregnant-women-residing-in-areas-with-intensive-pesticide-application
#11
María Martha Quintana, Berta Vera, Gladis Magnarelli, Natalia Guiñazú, María Gabriela Rovedatti
In rural populations, the proximity to areas with intensive pesticide application represents a risk factor of xenobiotic exposure. Here, we investigated whether newborns born to mothers residing in an area with intensive pesticide application show alterations in placental and neonatal morphometric standards, umbilical cord blood (UCB) biochemical parameters, and/or biomarkers related to oxidative stress and oxidative damage. Samples were collected from 151 healthy pregnant women residing in a rural area (rural group; RG) during the pesticide spraying (SS) and nonspraying (NSS) seasons, as well as from women from an urban population (control group; CG), and grouped according to the delivery type (vaginal or cesarean)...
July 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28715737/static-and-continuous-flow-through-pulsed-light-technology-for-pesticide-abatement-in-water
#12
Ana Beatriz Baranda, Amaia Lasagabaster, Iñigo Martínez de Marañón
Perspectives concerning pulsed light (PL) technology as a novel water decontamination treatment are overviewed in this work. Degradation of atrazine, malathion, chlorpyriphos-methyl and bromopropylate in aqueous solutions at different concentrations was performed employing static and continuous flow-through PL units. Results for both PL systems were compared in terms of efficacy of pesticides degradation and derived photoproducts formed. The pesticides degradation increased with the applied total fluence for both PL systems...
July 8, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28714172/a-study-of-dna-damage-in-buccal-cells-of-consumers-of-well-and-or-tap-water-using-the-comet-assay-assessment-of-occupational-exposure-to-genotoxicants
#13
Celia Vazquez Boucard, Larisa Lee-Cruz, Laurence Mercier, Martín Ramírez Orozco, Vania Serrano Pinto, Gerardo Anguiano, Linette Cazares, Daniel Díaz
Because of concerns that natural aquifers in the region of Todos Santos (Baja California Sur, Mexico) might be contaminated by organochlorine pesticides and heavy metals, a case-control study was conducted among consumers and non-consumers of well- and/or tap-water to determine risks to human health. This study was based on a genotoxic evaluation of buccal cells using the Comet assay technique. Levels of DNA damage in the consumers group were significantly higher than those of the control group. However, occupational exposure to genotoxicants showed to be the critical factor rather than water consumption...
July 17, 2017: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/28711003/environmentally-relevant-concentrations-of-herbicides-impact-non-target-species-at-multiple-sublethal-endpoints
#14
Simone Hasenbein, Jade Peralta, Sharon P Lawler, Richard E Connon
There is concern over herbicide exposure effects on aquatic primary production and zooplankton as herbicides are found in aquatic ecosystems at concentrations potentially toxic to phytoplankton. We first aimed to determine the effect concentrations (growth inhibition) and mixture interactions of the herbicides diuron (0.5 to 50μg/L) and hexazinone (0.5 to 40μg/L) on the green algae Pseudokirchneriella subcapitata. Secondly, we evaluated chronic effects on Daphnia magna that were periodically fed on P. subcapitata that had been exposed to low, medium, and high concentrations...
July 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28709981/relative-toxicity-for-indoor-semi-volatile-organic-compounds-based-on-neuronal-death
#15
Kevin Fournier, Emmanuel Baumont, Philippe Glorennec, Nathalie Bonvallot
BACKGROUND: Semi Volatile Organic Compounds (SVOCs) are contaminants commonly found in dwellings as a result of their use as plasticizers, flame retardants, or pesticides in building materials and consumer products. Many SVOCs are suspected of being neurotoxic, based on mammal experimentation (impairment of locomotor activity, spatial learning/memory or behavioral changes), raising the question of cumulative risk assessment. The aim of this work is to estimate the relative toxicity of such SVOCs, based on neuronal death...
July 11, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28708984/comparison-of-social-behavior-responses-of-japanese-medaka-oryzias-latipes-to-lethal-and-sublethal-chlorpyrifos-concentrations-at-different-exposure-times
#16
Fatma Khalil, Xuchun Qiu, Ik Joon Kang, Ismail Abo-Ghanema, Yohei Shimasaki, Yuji Oshima
Chlorpyrifos (CPF) is one of the most widely used insecticides and has been found in both urban and rural water bodies. In this study, we studied variations in the social behavioral patterns, swimming behavior, and brain acetylcholinesterase (AChE) activity of Japanese medaka exposed to lethal (0.12mg/L) and sublethal (0.012mg/L) concentrations of CPF after different exposure times. Group behavior performance (schooling, shoaling, and solitary) was determined on day 4 of lethal exposure and on days 4, 8, and 12 of sublethal exposure...
July 11, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28708418/vaccines-pesticides-and-narratives-of-exposure-and-evidence
#17
Elena Conis
This essay considers the cultural work performed by two public health narratives - the DDT narrative and the vaccine narrative - as they appeared in popular and professional discourse concerning two recent media events: controversy over an antivaccination film, and the emergence of a Zika global public health emergency. Like all narratives in the history of medicine, the stories historians and others tell about DDT and about vaccines organize a shared past to explain the present. They also point to a hoped-for future...
July 14, 2017: Canadian Bulletin of Medical History, Bulletin Canadien D'histoire de la Médecine
https://www.readbyqxmd.com/read/28704700/environmental-exposure-to-pesticides-and-the-risk-of-parkinson-s-disease-in-the-netherlands
#18
Maartje Brouwer, Anke Huss, Marianne van der Mark, Peter C G Nijssen, Wim M Mulleners, Antonetta M G Sas, Teus van Laar, Geert R de Snoo, Hans Kromhout, Roel C H Vermeulen
BACKGROUND: Exposure to pesticides has been linked to Parkinson's disease (PD), although associations between specific pesticides and PD have not been well studied. Residents of rural areas can be exposed through environmental drift and volatilization of agricultural pesticides. OBJECTIVES: Our aim was to investigate the association between lifetime environmental exposure to individual pesticides and the risk of PD, in a national case-control study. METHODS: Environmental exposure to pesticides was estimated using a spatio-temporal model, based on agricultural crops around the residential address...
July 10, 2017: Environment International
https://www.readbyqxmd.com/read/28704346/mortality-from-amyotrophic-lateral-sclerosis-and-parkinson-s-disease-among-different-occupation-groups-united-states-1985-2011
#19
John D Beard, Andrea L Steege, Jun Ju, John Lu, Sara E Luckhaupt, Mary K Schubauer-Berigan
Amyotrophic lateral sclerosis (ALS) and Parkinson's disease, both progressive neurodegenerative diseases, affect >1 million Americans (1,2). Consistently reported risk factors for ALS include increasing age, male sex, and cigarette smoking (1); risk factors for Parkinson's disease include increasing age, male sex, and pesticide exposure, whereas cigarette smoking and caffeine consumption are inversely associated (2). Relative to cancer or respiratory diseases, the role of occupation in neurologic diseases is much less studied and less well understood (3)...
July 14, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28702848/organic-solvent-exposure-and-depressive-symptoms-among-licensed-pesticide-applicators-in-the-agricultural-health-study
#20
Miriam Siegel, Sarah E Starks, Wayne T Sanderson, Freya Kamel, Jane A Hoppin, Fred Gerr
PURPOSE: Although organic solvents are often used in agricultural operations, neurotoxic effects of solvent exposure have not been extensively studied among farmers. The current analysis examined associations between questionnaire-based metrics of organic solvent exposure and depressive symptoms among farmers. METHODS: Results from 692 male Agricultural Health Study participants were analyzed. Solvent type and exposure duration were assessed by questionnaire. An "ever-use" variable and years of use categories were constructed for exposure to gasoline, paint/lacquer thinner, petroleum distillates, and any solvent...
July 12, 2017: International Archives of Occupational and Environmental Health
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