keyword
MENU ▼
Read by QxMD icon Read
search

Vitreous

keyword
https://www.readbyqxmd.com/read/27932048/fatal-intravenous-injection-of-potassium-is-postmortem-biochemistry-useful-for-the-diagnosis
#1
Cristian Palmiere, Maria Pia Scarpelli, Vincent Varlet, Pia Baumann, Katarzyna Michaud, Marc Augsburger
Fatal cases of potassium overdoses have traditionally been considered indemonstrable due postmortem biochemical investigation limits (mainly potassium determination in postmortem serum and vitreous humor). Nevertheless, some authors have expressed a divergent opinion over the years based on the results of their own investigations. In this study, we investigated left vitreous, right vitreous, postmortem serum from peripheral blood, postmortem serum from cardiac blood, urine, pericardial and cerebrospinal fluid potassium concentrations in 21 forensic autopsy cases...
November 27, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27930814/septic-ketoacidosis-a-potentially-lethal-entity-with-renal-tubular-epithelial-vacuolization
#2
Chong Zhou, Roger W Byard
Fatal ketoacidosis due to diabetes mellitus, alcoholism, and starvation may produce characteristic basal vacuolization of renal tubular epithelial cells (RTEC). Septic ketoacidosis has recently been recognized clinically as a distinct condition in which septicemia can lead to elevation of ketones and various anions unrelated to diabetes mellitus, alcoholism, or caloric deprivation. We report four lethal cases with significantly elevated vitreous ketones secondary to sepsis and/or severe localized infection in individuals with no history of diabetes mellitus, alcoholism, or starvation...
December 8, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27930546/vitreous-lavage-fluid-and-bronchoalveolar-lavage-fluid-have-equal-diagnostic-value-in-sarcoidosis
#3
Kazuichi Maruyama, Tohru Inaba, Tsutomu Tamada, Toru Nakazawa
Here, we elucidate the immunological features of both bronchoalveolar lavage fluid (BALF) and vitreous lavage fluid (VLF) samples from patients with histopathologically verified sarcoidosis. In addition, we assess the safety of vitrectomy in sarcoidosis patients by investigating the occurrence of complications and the recovery of visual acuity.Twenty-two eyes of 22 patients with tissue-proven sarcoidosis were enrolled in this study. BALF and VLF samples were obtained and compared in each patient, and the clinical course (including visual acuity) was followed...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930538/binocular-indirect-ophthalmo-microscope-assistant-gas-perfused-pars-plana-vitrectomy-a-novel-technique-for-vitreous-sample-acquisition
#4
Luyi Zhang, Xiaoli Yang, Qingqing Zheng, Miaoqin Wu
The vitreous sample has been used for the diagnosis of uveitis and intraocular malignancy for decades. The sample volume is usually limited to 1 mL with current techniques. In the present study, a novel technique for higher amount of vitreous sample acquisition, that is, Binocular Indirect Ophthalmo Microscope-assistant gas-perfused pars plana vitrectomy (BAG-PPV) was invented.For diagnostic purpose, BAG-PPV with 23-ga vitrectomy system was performed on a 54-year-old Chinese male with the symptom of bilateral atypical uveitis...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930456/effects-of-a-modified-vitrectomy-probe-in-small-gauge-vitrectomy-an-experimental-study-on-the-flow-and-on-the-traction-exerted-on-the-retina
#5
Stanislao Rizzo, Gualtiero Fantoni, Giovanni de Santis, Jaw-Chyng Lormen Lue, Jonathan Ciampi, Michele Palla, Federica Genovesi Ebert, Alfonso Savastano, Carmelo De Maria, Giovanni Vozzi, Rodrigo A Brant Fernandes, Francesco Faraldi, Giuseppe Criscenti
PURPOSE: Thorough this experimental study, the physic features of a modified 23-gauge vitrectomy probe were evaluated in vitro. METHODS: A modified vitrectomy probe to increase vitreous outflow rate with a small-diameter probe, that also minimized tractional forces on the retina, was created and tested. The "new" probe was created by drilling an opening into the inner duct of a traditional 23-gauge probe with electrochemical or electrodischarge micromachining. Both vitreous outflow and tractional forces on the retina were examined using experimental models of vitreous surgery...
December 7, 2016: Retina
https://www.readbyqxmd.com/read/27930437/case-of-metastatic-urothelial-carcinoma-of-the-retina-and-vitreous
#6
Katherine E Whalen, Ralph C Eagle, Tamara R Vrabec
PURPOSE: To report a rare case of vitreo-retinal metastasis from urothelial carcinoma of the bladder. METHODS: Case report. RESULTS: A 55-year-old man with a history of bladder cancer developed atypical vitritis and a white fundus mass. Intravenous fluorescein angiography demonstrated connection between the retinal and tumor vasculature consistent with a retinal malignancy. Cytologic analysis of the vitreous sample revealed large, atypical cells with pleomorphic nuclei, mucin vacuoles, and rare mitotic figures...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27930435/polypoidal-choroidal-vasculopathy-a-clinicopathologic-study
#7
Kareem Moussa, Michele M Bloomer, Daniel M Schwartz, Carolyn K Pan, Brian C Toy, Joseph B Crawford, Armin R Afshar
PURPOSE: To present a unique case of polypoidal choroidal vasculopathy presenting as a blind, painful eye with a suspected intraocular mass, and to correlate clinical findings with histopathologic studies. METHODS: Clinical case report and literature review. RESULTS: A 58-year-old Vietnamese man presented with a blind, painful eye with concern for an intraocular mass. B-scan ultrasonography showed massive intraocular hemorrhage and could not rule out a tumor...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27929753/generation-and-characterization-of-abbv642-a-dual-variable-domain-immunoglobulin-molecule-dvd-ig-that-potently-neutralizes-vegf-and-pdgf-bb-and-is-designed-for-the-treatment-of-exudative-age-related-macular-degeneration
#8
Kun Ding, Lucia Eaton, Diana Bowley, Matthew Rieser, Qing Chang, Maria C Harris, Anca Clabbers, Feng Dong, Jikui Shen, Sean F Hackett, Debra S Touw, Jacqueline Bixby, Suju Zhong, Lorenzo Benatuil, Sahana Bose, Christine Grinnell, Gregory M Preston, Ramesh Iyer, Ramkrishna Sadhukhan, Susan Marchie, Gary Overmeyer, Tariq Ghayur, Deborah A van Riet, Shibo Tang, Peter A Campochario, Jijie Gu
Exudative age-related macular degeneration (AMD) is the most common cause of moderate and severe vision loss in developed countries. Intraocular injections of vascular endothelial growth factor (VEGF or VEGF-A)-neutralizing proteins provide substantial benefit, but frequent, long-term injections are needed. In addition, many patients experience initial visual gains that are ultimately lost due to subretinal fibrosis. Preclinical studies and early phase clinical trials suggest that combined suppression of VEGF and platelet-derived growth factor-BB (PDGF-BB) provides better outcomes than suppression of VEGF alone, due to more frequent regression of neovascularization (NV) and suppression of subretinal fibrosis...
December 8, 2016: MAbs
https://www.readbyqxmd.com/read/27928876/increased-levels-of-alphab-crystallin-in-vitreous-fluid-of-patients-with-proliferative-diabetic-retinopathy-and-correlation-with-vascular-endothelial-growth-factor
#9
Wei Chen, Qianyi Lu, Li Lu, Huaijin Guan
BACKGROUND: AlphaB-crystallin has been shown to have angiogenic properties. The purpose of this study was to determine the levels of alphaB-crystallin in the vitreous fluid of patients with proliferative diabetic retinopathy (PDR) and to confirm the association between the expression level of alphaB-crystallin and vascular endothelial growth factor (VEGF). METHODS: Vitreous samples were collected before vitrectomy from 46 eyes of 46 consecutive patients with PDR and 19 patients without diabetes mellitus (DM) had vitrectomy for idiopathic macular hole (IMH)...
December 7, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27928412/posterior-vitreous-detachment-associated-with-non-arteritic-ischaemic-optic-neuropathy
#10
Bailey Shen, Peter W MacIntosh
It has been hypothesised that non-arteritic ischaemic optic neuropathy is caused by vitreous traction on the optic nerve. The authors recently took care of a patient who developed a posterior vitreous detachment shortly after she was diagnosed with non-arteritic ischaemic optic neuropathy. Her visual field spontaneously improved after the posterior vitreous detachment. This case report provides some evidence that non-arteritic ischaemic optic neuropathy, vitreous traction, and posterior vitreous detachment may be related...
October 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27926755/surface-area-of-detachment-proliferative-vitreoretinopathy-and-pulse-pressure-but-not-ages-are-associated-with-retinal-redetachment
#11
Bernardina T Fokkens, Douwe J Mulder, Michiel B Nugteren, Casper G Schalkwijk, Jean L Scheijen, Andries J Smit, Leonoor I Los
Purpose: Advanced glycation endproducts (AGEs) have been suggested to play a role in retinal redetachment by promoting proliferative vitreoretinopathy (PVR). The purpose of this study was to investigate whether AGEs, in combination with other clinical characteristics, were able to identify patients at high risk for redetachment after vitrectomy for rhegmatogenous retinal detachment (RRD). Methods: In this prospective cohort study, 410 RRD patients were included...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27920489/bleb-related-infections-clinical-characteristics-risk-factors-and-outcomes-in-an-asian-population
#12
Zhu Li Yap, You Chuen Chin, Judy Yu-Fen Ku, Tat Keong Chan, Gillian Teh, Monisha Esther Nongpiur, Tin Aung, Shamira A Perera
PURPOSE: Comparison of the demographic, ocular, systemic and microbiological characteristics of eyes with bleb related infection (BRI) and bleb related endophthalmitis (BRE). METHODS: Retrospective chart review of patients with BRI from January 1996-July 2013. Identification done via the center's longstanding endophthalmitis audit, BRI audit and laboratory database identifying all conjunctival swabs from blebs. Blebitis was defined as anterior segment inflammation with mucopurulent material in or around the bleb, with anterior chamber cells but no hypopyon...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27918825/early-postnatal-hyperoxia-in-mice-leads-to-severe-persistent-vitreoretinopathy
#13
Paul G McMenamin, Rachel Kenny, Sjakon Tahija, Jeremiah Lim, Cecilia Naranjo Golborne, Xiangting Chen, Sheena Bouch, Foula Sozo, Bang Bui
Purpose: To describe a mouse model of hyperoxia-induced vitreoretinopathy that replicated some of the clinical and pathologic features encountered in infants with severe retinopathy of prematurity and congenital ocular conditions such as persistent hyperplastic primary vitreous. Methods: Experimental mice (C57BL/6J) were exposed to 65% oxygen between postnatal days (P)0 to P7 and studied at P10, P14, and 3, 5, 8, 20, and 40 weeks. Controls were exposed to normoxic conditions...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27917719/prevention-and-treatment-of-postoperative-endophthalmitis-using-povidone-iodine
#14
Hiroyuki Shimada, Hiroyuki Nakashizuka, Andrzej Grzybowski
Postoperative endophthalmitis is typically caused by patient's conjunctival bacterial flora or contaminated solutions and instruments. Visual outcome is often poor in severe cases, and treatment is especially difficult when endophthalmitis is caused by multidrug resistant bacteria. Povidone-iodine is used worldwide due to its wide-spectrum antimicrobial activity, absence of resistant bacteria to povidone-iodine, and low cost. Furthermore, the effective concentration against microorganisms and safe concentration for ocular tissues have been well established...
December 4, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27916715/360-degree-trabeculotomy-for-medically-refractory-glaucoma-following-cataract-surgery-and-juvenile-open-angle-glaucoma
#15
Maria E Lim, Jennifer B Dao, Sharon F Freedman
PURPOSE: While angle surgeries show good success in primary congenital glaucoma, reported success in glaucoma following cataract surgery (GFCS) and juvenile open angle glaucoma (JOAG) is variable and with relatively short follow-up. We evaluated longer-term outcomes of 360-trabeculotomy for medically-refractory GFCS and JOAG. DESIGN: Retrospective case series. METHODS: First operated eyes of consecutive patients with medically-refractory GFCS and JOAG in a single-surgeon pediatric glaucoma practice who underwent illuminated microcatheter-assisted 360-trabeculotomy from 2/2008-6/2015 were reviewed...
December 1, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27913441/size-and-vitreomacular-attachment-of-primary-full-thickness-macular-holes
#16
Elise Philippakis, Franck Amouyal, Aude Couturier, Elise Boulanger-Scemama, Alain Gaudric, Ramin Tadayoni
PURPOSE: To study the relationship between the size of primary full-thickness macular hole (MH) and the vitreomacular attachment status. DESIGN: Single-centre retrospective observational case series. METHODS: The records of 100 consecutive eyes operated for primary full-thickness MH were retrospectively reviewed. The vitreous status and MH diameter were assessed on the preoperative optical coherence tomography scans. MH were classified depending on the presence or absence of vitreomacular traction (VMT) and their size as small (<250 µm), medium (250-400 µm) and large (>400 µm), as suggested in the International VMT Study Group Classification...
December 2, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27913439/retinitis-pigmentosa-associated-cystoid-macular-oedema-pathogenesis-and-avenues-of-intervention
#17
REVIEW
S Strong, G Liew, M Michaelides
Hereditary retinal diseases are now the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales, of which retinitis pigmentosa (RP) is the most common disorder. RP may be complicated by cystoid macular oedema (CMO), causing a reduction of central vision. The underlying pathogenesis of RP-associated CMO (RP-CMO) remains uncertain, however, several mechanisms have been proposed, including: (1) breakdown of the blood-retinal barrier, (2) failure (or dysfunction) of the pumping mechanism in the retinal pigment epithelial, (3) Müller cell oedema and dysfunction, (4) antiretinal antibodies and (5) vitreous traction...
December 2, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27909796/-clinical-morphological-and-molecular-biological-characteristics-of-the-aging-eye
#18
M R R Böhm, H Thomasen, F Parnitzke, K-P Steuhl
BACKGROUND: The physiological aging of the eye is associated with loss of visual function. Age-related changes of the eye can result in ophthalmological diseases. The aim of this article is to display morphological, histological and molecular biological alterations of the aging eye. MATERIAL AND METHODS: A web-based search and review of the literature for aging of the visual system including cornea, lens, vitreous humor, retina, retinal pigment epithelium (RPE), choroidea and optic nerve were carried out...
December 1, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27905004/ocular-disposition-of-%C3%A2-8-tetrahydrocannabinol-from-various-topical-ophthalmic-formulations
#19
Nagendra S Punyamurthula, Goutham R Adelli, Waseem Gul, Michael A Repka, Mahmoud A ElSohly, Soumyajit Majumdar
The purposes of this project are to enhance the trans-membrane penetration of Δ(8)-Tetrahydrocannabinol (Δ(8)-THC) and to study the effect of various lipid based systems in delivering the compound, non-invasively, to anterior and posterior ocular chambers. Solid lipid nanoparticles (SLNs), fast gelling films were manufactured using high pressure homogenization and melt cast techniques, respectively. The formulations were characterized for drug content, entrapment efficiency, particle size and subsequently evaluated in vitro for trans-corneal permeation...
November 30, 2016: AAPS PharmSciTech
https://www.readbyqxmd.com/read/27904945/-sarcoidosis-and-uveitis-an-update
#20
REVIEW
J G Garweg
Ocular involvement in sarcoidosis is present in up to one third of patients and is frequently manifested before the underlying systemic disease has been diagnosed. With a view to the therapeutic consequences an early diagnosis of the underlying disease is advantageous. In cases of visual loss early diagnostic measures include invasive procedures, such as ultrasound-guided bronchoalveolar lavage and transbronchial biopsy, if nodular conjunctival or cutaneous manifestations which would confirm the diagnosis are not present...
November 30, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
keyword
keyword
6960
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"