keyword
MENU ▼
Read by QxMD icon Read
search

3D porous titanium

keyword
https://www.readbyqxmd.com/read/29511441/a-novel-hybrid-3d-printed-titanium-scaffold-for-osteogenesis-in-a-rabbit-calvarial-defect-model
#1
Bo Yin, Bingjian Xue, Zhihong Wu, Jiguang Ma, Keming Wang
The aim of this study was to explore an innovative method to improve the osteogenic ability of porous titanium. We used gelatin (Gel) and nano-hydroxyapatite (nHA) to construct micro-scaffolds within the pores of porous titanium alloy. We compared three groups: control, Gel:nHA = 1:0, and Gel:nHA = 1:1. We assessed cell attachment, cell proliferation, and osteogenic (alkaline phosphatase [ALP] and collagen type 1 [Col-1]) and cytoskeletal (Talin) gene and protein expression in MC3T3-E1 cells. We also evaluated osteogenic abilities in a rabbit calvarial defect model...
2018: American Journal of Translational Research
https://www.readbyqxmd.com/read/29496624/bony-ingrowth-potential-of-3d-printed-porous-titanium-alloy-a-direct-comparison-of-interbody-cage-materials-in-an-in-vivo-ovine-lumbar-fusion-model
#2
Kirk McGilvray, Jeremiah Easley, Howard B Seim, Daniel Regan, Sigurd H Berven, Wellington K Hsu, Thomas E Mroz, Christian M Puttlitz
BACKGROUND CONTEXT: There is significant variability in the materials commonly used for interbody cages in spine surgery. It is theorized that 3-D printed interbody cages utilizing porous titanium material can provide more consistent bone ingrowth and biological fixation. PURPOSE: The purpose of this study was to provide an evidence-based approach to decision making regarding interbody materials for spinal fusion. STUDY DESIGN: Comparative animal study...
February 26, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29481493/contour-restoration-of-over-resected-mandibular-angle-and-lower-border-by-reduction-mandibuloplasty-using-three-dimensional-planning-and-computer-aided-design-and-manufacturing-custom-made-titanium-implants
#3
Jae Man Woo, Seung-Hak Baek, Jong-Cheol Kim, Jin-Young Choi
OBJECTIVE: The purpose of this clinical report was to introduce a new methodology for contour restoration of the over-resected mandible by reduction mandibuloplasty using 3-dimensional (3D) planning and computer-assisted design and manufacturing (CAD-CAM) custom-made titanium implants. PATIENT AND METHOD: A 20-year-old male patient had undergone reduction of the zygoma and mandibular angle and lower border for esthetic reason 1 year ago at a private clinic. However, he was not satisfied with surgical outcome and wanted to restore his original facial volume and contour...
February 23, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29464784/total-nasal-reconstruction-with-3d-custom-made-porous-titanium-prosthesis-and-free-thoracodorsal-artery-perforator-flap-a-case-report
#4
Quentin Qassemyar, Nathaniel Assouly, Yoni Madar, Stéphane Temam, Frédéric Kolb
Total nasal reconstruction is a challenging surgical procedure which usually involves a free flap, forehead flap, and cartilage grafts. In certain failure situations where patients do not accept the idea of anaplastology, possibilities become very limited. We report the case of a patient who underwent several reconstruction steps with multiple failures including free and local flaps and cartilage harvests which showed recurrent episodes of necrosis and infection leading to melting and collapse of reconstructed structures...
February 21, 2018: Microsurgery
https://www.readbyqxmd.com/read/29414477/effect-of-porous-orthopaedic-implant-material-and-structure-on-load-sharing-with-simulated-bone-ingrowth-a-finite-element-analysis-comparing-titanium-and-peek
#5
R Dana Carpenter, Brett S Klosterhoff, F Brennan Torstrick, Kevin T Foley, J Kenneth Burkus, Christopher S D Lee, Ken Gall, Robert E Guldberg, David L Safranski
Osseointegration of load-bearing orthopaedic implants, including interbody fusion devices, is critical to long-term biomechanical functionality. Mechanical loads are a key regulator of bone tissue remodeling and maintenance, and stress-shielding due to metal orthopaedic implants being much stiffer than bone has been implicated in clinical observations of long-term bone loss in tissue adjacent to implants. Porous features that accommodate bone ingrowth have improved implant fixation in the short term, but long-term retrieval studies have sometimes demonstrated limited, superficial ingrowth into the pore layer of metal implants and aseptic loosening remains a problem for a subset of patients...
January 30, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29249195/surface-nanotopography-induced-favorable-modulation-of-bioactivity-and-osteoconductive-potential-of-anodized-3d-printed-ti-6al-4v-alloy-mesh-structure
#6
K C Nune, Rdk Misra, X Gai, S J Li, Y L Hao
The objective of the study described here is to fundamentally elucidate the biological response of 3D printed Ti-6Al-4V alloy mesh structures that were surface modified to introduce titania nanotubes with an average pore size of ∼80 nm via an electrochemical anodization process from the perspective of enhancing bioactivity. The bioactivity of the mesh structures were analyzed through immersion test in simulated body fluid, which confirmed the nucleation and growth of fine globular nanoscale apatite on the nanoporous titania-modified (anodized) mesh structure surface, and agglomerated apatite with fine flakes of apatite crystals on as-fabricated mesh structure surface, that were rich in calcium and phosphorous...
March 2018: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29233510/patient-specific-puzzle-implant-preformed-with-3d-printed-rapid-prototype-model-for-combined-orbital-floor-and-medial-wall-fracture
#7
Young Chul Kim, Kyung Hyun Min, Jong Woo Choi, Kyung S Koh, Tae Suk Oh, Woo Shik Jeong
BACKGROUND: The management of combined orbital floor and medial wall fractures involving the inferomedial strut is challenging due to absence of stable cornerstone. In this article, we proposed surgical strategies using customized 3D puzzle implant preformed with Rapid Prototype (RP) skull model. METHODS: Retrospective review was done in 28 patients diagnosed with combined orbital floor and medial wall fracture. Using preoperative CT scans, original and mirror-imaged RP skull models for each patient were prepared and sterilized...
April 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29215451/mandibular-reconstruction-using-a-customized-three-dimensional-titanium-implant-applied-on-the-lingual-surface-of-the-mandible
#8
You-Young Jo, Seong-Gon Kim, Min-Keun Kim, Sung-Ho Shin, Janghoon Ahn, Hyun Seok
A patient had a right mandibular defect due to resection of an ameloblastoma. Previously, the defect had been reconstructed by an iliac bone graft, and subsequently, a titanium mesh with xenograft was used. However, it was not successfully reconstructed. For the recovery of mandible continuity and rehabilitation of jaw movement, we manufactured a customized 3-dimensional titanium implant by computer-aided design and manufacturing and electron beam melting technology. This implant was designed to have a porous body structure and lingual plate...
March 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28884523/response-of-umbilical-cord-mesenchymal-stromal-cells-to-varying-titanium-topographical-signals
#9
Ines Lauria, Miriam Höner, Sebastian Kant, Roswitha Davtalab, Thomas Weik, Katrin Sternberg, Horst Fischer
A wide variety of titanium implant modifications have been developed to improve tissue- or cell-material interactions including bone bonding, implant failure, and contact osteogenesis. Osteogenesis can be stimulated by mechanobiological signals such as topography though translation of in vivo reactions to in vitro bioactivity and stem cell culture data, and vice versa, is challenging. We hypothesized that a systematic in vitro approach comparing clinically well-accepted implant surface topographical modifications could shed light on potential cell biological mechanisms provoked by submicron-, micron- or macrostructured surfaces...
January 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28832345/biomimetic-surface-functionalization-of-clinically-relevant-metals-used-as-orthopaedic-and-dental-implants
#10
Elena García-Gareta, Jia Hua, Alodia Orera, Nupur Kohli, Jonathan C Knowles, Gordon W Blunn
Titanium and its alloys or tantalum (Ta) are materials used in orthopaedic and dental implants due to their excellent mechanical properties and biocompatibility. However, their bioactivity and osteoconductivity is low. With a view to improving the bioactivity of these materials we hypothesised that the surface of Ta and TiAl6V4 can be functionalised with biomimetic, amorphous nano-sized calcium phosphate (CaP) apatite-like deposits, instead of creating uniform coatings, which can lead to flaking, delamination and poor adherence...
November 22, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28797809/the-role-of-titanium-dioxide-on-the-morphology-microstructure-and-bioactivity-of-grafted-cellulose-hydroxyapatite-nanocomposites-for-a-potential-application-in-bone-repair
#11
Saeed Saber-Samandari, Hamed Yekta, Sara Ahmadi, Kadhim Alamara
Fabrication and characterization of a novel 3D nanocomposite scaffold have been reported in this research. The purpose of developing this new 3D nanocomposite scaffolds is introducing an alternative treatment for bone tissue replacement. Outcomes confirmed that the morphology, microstructure and mechanical properties of synthesized 3D nanocomposite scaffolds closely mimics the properties of real bone tissue. The 3D nanocomposite scaffolds compose of nanoparticle hydroxyapatite which is embedded in the semi-IPN of polyacrylamide-grafted cellulose by free radical polymerization...
January 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28765800/fortifying-the-bone-implant-interface-part-2-an-in-vivo-evaluation-of-3d-printed-and-tps-coated-triangular-implants
#12
Regina F MacBarb, Derek P Lindsey, Shane A Woods, Peggy A Lalor, Mukund I Gundanna, Scott A Yerby
BACKGROUND: Minimally invasive surgical fusion of the sacroiliac (SI) joint using machined solid triangular titanium plasma spray (TPS) coated implants has demonstrated positive clinical outcomes in SI joint pain patients. Additive manufactured (AM), i.e. 3D-printed, fenestrated triangular titanium implants with porous surfaces and bioactive agents, such as nanocrystalline hydroxyapatite (HA) or autograft, may further optimize bony fixation and subsequent biomechanical stability. METHODS: A bilateral ovine distal femoral defect model was used to evaluate the cancellous bone-implant interfaces of TPS-coated and AM implants...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28765799/fortifying-the-bone-implant-interface-part-1-an-in-vitro-evaluation-of-3d-printed-and-tps-porous-surfaces
#13
Regina F MacBarb, Derek P Lindsey, Chelsea S Bahney, Shane A Woods, Mark L Wolfe, Scott A Yerby
BACKGROUND: An aging society and concomitant rise in the incidence of impaired bone health have led to the need for advanced osteoconductive spinal implant surfaces that promote greater biological fixation (e.g. for interbody fusion cages, sacroiliac joint fusion implants, and artificial disc replacements). Additive manufacturing, i.e. 3D-printing, may improve bone integration by generating biomimetic spinal implant surfaces that mimic bone morphology. Such surfaces may foster an enhanced cellular response compared to traditional implant surfacing processes...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28689135/deformation-and-fatigue-of-tough-3d-printed-elastomer-scaffolds-processed-by-fused-deposition-modeling-and-continuous-liquid-interface-production
#14
Andrew T Miller, David L Safranski, Catherine Wood, Robert E Guldberg, Ken Gall
Polyurethane (PU) based elastomers continue to gain popularity in a variety of biomedical applications as compliant implant materials. In parallel, advancements in additive manufacturing continue to provide new opportunities for biomedical applications by enabling the creation of more complex architectures for tissue scaffolding and patient specific implants. The purpose of this study was to examine the effects of printed architecture on the monotonic and cyclic mechanical behavior of elastomeric PUs and to compare the structure-property relationship across two different printing approaches...
July 1, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28629601/a-custom-made-temporomandibular-joint-prosthesis-for-fabrication-by-selective-laser-melting-finite-element-analysis
#15
Xiangliang Xu, Danmei Luo, Chuanbin Guo, Qiguo Rong
A novel and custom-made selective laser melting (SLM) 3D-printed alloplastic temporomandibular joint (TMJ) prosthesis is proposed. The titanium-6aluminium-4vanadium (Ti-6Al-4V) condyle component and ultra-high molecular weight polyethylene (UHMWPE) fossa component comprised the total alloplastic TMJ replacement prosthesis. For the condyle component, an optimized tetrahedral open-porous scaffold with combined connection structures, i.e. an inlay rod and an onlay plate, between the prosthesis and remaining mandible was designed...
August 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28578109/reconstruction-of-thoracic-spine-using-a-personalized-3d-printed-vertebral-body-in-adolescent-with-t9-primary-bone-tumor
#16
Wen Jie Choy, Ralph J Mobbs, Ben Wilcox, Steven Phan, Kevin Phan, Chester E Sutterlin
BACKGROUND: Neurosurgery and spine surgery have the potential to benefit from the use of 3-dimensional printing (3DP) technology due to complex anatomic considerations and the delicate nature of surrounding structures. We report a procedure that uses a 3D-printed titanium T9 vertebral body implant post T9 vertebrectomy for a primary bone tumor. CASE DESCRIPTION: A 14-year-old female presented with progressive kyphoscoliosis and a pathologic fracture of the T9 vertebra with sagittal and coronal deformity due to a destructive primary bone tumor...
September 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28474182/homogenous-scaffold-based-cranial-skull-implant-modelling-and-structural-analysis-unit-cell-algorithm-meshless-approach
#17
V Phanindra Bogu, Y Ravi Kumar, Asit Kumar Khanra
This computational study explores a unique modelling approach of the cranial implant, homogenous scaffold algorithm and meshless method, respectively. This meshless method is employed to review the implant underneath intracranial pressure (ICP) conditions with a standard ICP range of 7 mm of Hg to 15 mm of Hg. The algorithm is used to introduce uniform porosity within the implant enabling the implant behaviour with respect to ICP conditions. However, increase in the porosity leads to variation in deformation and equivalent stress, respectively...
November 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28350023/topochemical-synthesis-and-photocatalytic-activity-of-3d-hierarchical-batio-3-microspheres-constructed-from-crystal-axis-oriented-nanosheets
#18
Chang-Ke Chen, Shi-Xi Zhao, Qian-Long Lu, Kai Luo, Xi-Hui Zhang, Ce-Wen Nan
Novel BaTiO3 hierarchical porous microspheres were achieved by using H2 Ti2 O5 ·H2 O (HTO) hierarchical microspheres as a precursor template via a facile solvothermal method. Interestingly, the BaTiO3 microspheres were constructed with two-dimensional (2D) nanosheets, which were composed of many order nanocrystals with crystal-axis-orientation. The special hierarchical structure, which is both macroporous and mesoporous, exhibits a large specific surface area and a high total pore volume. The photocatalytic performance of BaTiO3 hierarchical microspheres for degradation of methyl orange (MO) under UV-light irradiation was tested, its apparent rate being up to 0...
April 11, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28338421/harnessing-the-osteogenicity-of-in-vitro-stem-cell-derived-mineralized-extracellular-matrix-as-3d-biotemplate-to-guide-bone-regeneration
#19
Yoke Chin Chai, Johanna Bolander, Ioannis Papantoniou, Jennifer Patterson, Jef Vleugels, Jan Schrooten, Frank P Luyten
Advanced biomaterials that are capable of guiding robust bone regeneration are highly demanded for translational therapy of bone defects or bone augmentation in clinics. One of the strategic approaches is to produce tissue engineering (TE) constructs that mediate bone regeneration by recapitulating the natural bone formation or healing process. In this study, we aimed at producing devitalized mineralized carriers with augmented bone forming capacity via a modified culture protocol (i.e., culture conditions with high calcium and/or phosphate concentrations) that first promotes cell growth and, subsequently, mineralized extracellular matrix (ECM) deposition by human periosteum-derived osteoprogenitor cells (hPDCs) on additive manufactured three-dimensional (3D) porous titanium (Ti)-based scaffolds...
March 24, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28251470/3d-printed-porous-titanium-changed-femoral-head-repair-growth-patterns-osteogenesis-and-vascularisation-in-porous-titanium
#20
Wei Zhu, Yan Zhao, Qi Ma, Yingjie Wang, Zhihong Wu, Xisheng Weng
Osteonecrosis of the femoral head (ONFH) is a major cause of morbidity, and total hip arthroplasty is both traumatic and expensive. Here, we created a gelatine scaffold embedded in uniquely shaped, 3D-printed porous titanium parts, which could attract and promote the proliferation of osteoblasts as well as bone regeneration, as the extracellular matrix (ECM) does in vivo. Interestingly, after hybridisation with platelets, the scaffold exhibited a low yet considerable rate of stable, safe and long-term growth factor release...
April 2017: Journal of Materials Science. Materials in Medicine
keyword
keyword
69586
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"