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3D titanium implants

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https://www.readbyqxmd.com/read/28899562/the-design-production-and-clinical-application-of-3d-patient-specific-implants-with-drilling-guides-for-acetabular-surgery
#1
B J Merema, J Kraeima, K Ten Duis, K W Wendt, R Warta, E Vos, R H Schepers, M J H Witjes, F F A IJpma
An innovative procedure for the development of 3D patient-specific implants with drilling guides for acetabular fracture surgery is presented. By using CT data and 3D surgical planning software, a virtual model of the fractured pelvis was created. During this process the fracture was virtually reduced. Based on the reduced fracture model, patient-specific titanium plates including polyamide drilling guides were designed, 3D printed and milled for intra-operative use. One of the advantages of this procedure is that the personalised plates could be tailored to both the shape of the pelvis and the type of fracture...
August 30, 2017: Injury
https://www.readbyqxmd.com/read/28892256/possibility-of-quantitative-t2-mapping-mri-of-cartilage-near-metal-in-high-tibial-osteotomy-a-human-cadaver-study
#2
Joost Verschueren, Duncan E Meuffels, Esther E Bron, Stefan Klein, Gert-Jan Kleinrensink, Jan A N Verhaar, Sita M A Bierma-Zeinstra, Gabriel P Krestin, Piotr A Wielopolski, Max Reijman, Edwin H G Oei
T2-mapping is a widely used quantitative MRI technique in osteoarthritis research. An important challenge for its application in the context of high tibial osteotomy (HTO) is the presence of metallic fixation devices. In this study, we evaluated the possibility of performing T2-mapping after a HTO, by assessing the extent of magnetic susceptibility artifacts and the influence on T2 relaxation times caused by two commonly used fixation devices. T2-mapping with a 3D fast spin-echo sequence at 3 Tesla was performed on 11 human cadaveric knee joints before and after implantation of a titanium plate and screws (n = 5) or cobalt chrome staples(n = 6)...
September 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28888428/displacement-comparison-of-cad-cam-titanium-and-zirconia-abutments-to-implants-with-different-conical-connections
#3
Burak Yilmaz, Shervin Hashemzadeh, Jeremy D Seidt, Nancy L Clelland
PURPOSE: To compare the displacements of CAD-CAM zirconia and titanium abutments into different internal connection systems after torquing. METHODS: OsseoSpeed EV and OsseoSpeed TX implants (n=10) were placed in resin blocks. Zirconia and titanium abutments (n=5) were first hand tightened and then tightened to the recommended torque (20Ncm for TX and 25Ncm for EV). Displacements of abutments between screw tightening by hand and torque driver was measured using three-dimensional digital image correlation (3D DIC) technique...
September 6, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28884523/response-of-umbilical-cord-mesenchymal-stromal-cells-to-varying-titanium-topographical-signals
#4
Ines Lauria, Miriam Höner, Sebastian Kant, Roswitha Davtalab, Thomas Weik, Katrin Sternberg, Horst Fischer
A wide variety of titanium implant modifications have been developed to improve tissue- or cell-material interactions including bone bonding, implant failure, and contact osteogenesis. Osteogenesis can be stimulated by mechanobiological signals such as topography though translation of in vivo reactions to in vitro bioactivity and stem cell culture data, and vice versa, is challenging. We hypothesized that a systematic in vitro approach comparing clinically well-accepted implant surface topographical modifications could shed light on potential cell biological mechanisms provoked by submicron-, micron- or macrostructured surfaces...
September 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28855286/improved-methods-for-acrylic-free-implants-in-non-human-primates-for-neuroscience-research
#5
Jacqueline A Overton, Dylan F Cooke, Adam B Goldring, Steven A Lucero, Conor Weatherford, Gregg H Recanzone
Traditionally, head fixation devices and recording cylinders have been implanted in non-human primates (NHP) using dental acrylic, in spite of several shortcomings associated with acrylic. The use of more biocompatible materials such as titanium and PEEK is becoming more prevalent in NHP research. We describe a cost-effective set of procedures that maximizes the integration of headposts and recording cylinders with the animal's tissues while reducing surgery time. Nine rhesus monkeys were implanted with titanium headposts and one of these was also implanted with a recording chamber...
August 30, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28832345/biomimetic-surface-functionalization-of-clinically-relevant-metals-used-as-orthopaedic-and-dental-implants
#6
Elena García-Gareta, Jia Hua, Alodia Orera, Nupur Kohli, Jonathan C Knowles, Gordon W Blunn
Titanium and its alloys or tantalum (Ta) are materials used in orthopaedic and dental implants due to their excellent mechanical properties and biocompatibility. However, their bioactivity and osteoconductivity is low. With a view to improving these materials bioactivity we hypothesised that the surface of Ta and TiAl6V4 can be functionalised with biomimetic, amorphous nano-sized calcium-phosphate (CaP) apatite-like deposits, instead of creating uniform coatings, which can lead to flaking, delamination and poor adherence...
August 23, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28828975/customized-titanium-mesh-based-on-the-3d-printed-model-vs-manual-intraoperative-bending-of-titanium-mesh-for-reconstructing-of-orbital-bone-fracture-a-randomized-clinical-trial
#7
Shahrokh Raisian, Hamid Reza Fallahi, Kazem S Khiabani, Mehdi Heidarizadeh, Sadaf Azdoo
BACKGROUND: This study was aimed to compare the efficacy of customized patient-specific titanium mesh based on 3D printed model with intra-operative bending of titanium mesh for reconstructing of orbital floor fracture. METHODS: This study was prospectively conducted on 10 patients with unilateral orbital floor fractures caused by accident or falls. In intervention group (n=5), the CT-scan slices were used for generating 3D reconstruction of both affected and unaffected orbits...
August 21, 2017: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/28820570/engineering-of-micro-to-nanostructured-3d-printed-drug-releasing-titanium-implants-for-enhanced-osseointegration-and-localized-delivery-of-anticancer-drugs
#8
Shaheer Maher, Gagandeep Kaur, Luis Lima-Marques, Andreas Evdokiou, Dusan Losic
Primary and secondary bone cancers are major causes of pathological bone fractures which are usually treated through implant fixation and chemotherapy. However, both approaches face many limitations. On one hand, implants may suffer from poor osseointegration, and their rejection results in repeated surgery, patient's suffering, and extensive expenses. On the other hand, there are severe systemic adverse effects of toxic chemotherapeutics which are administrated systemically. In this paper, in order to address these two problems, we present a new type of localized drug-releasing titanium implants with enhanced implants' biointegration and drug release capabilities that could provide a high concentration of anticancer drugs locally to treat bone cancers...
August 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28790331/3d-printed-personalized-titanium-plates-improve-clinical-outcome-in-microwave-ablation-of-bone-tumors-around-the-knee
#9
Limin Ma, Ye Zhou, Ye Zhu, Zefeng Lin, Lingling Chen, Yu Zhang, Hong Xia, Chuanbin Mao
Microwave ablation has been widely accepted in treating bone tumor. However, its procedure is time-consuming and usually results in postoperative fractures. To solve this problem, we designed and fabricated titanium plates customized to the patients' bone structures. The personalized titanium plates were then used for fixation after the removal of tumorous tissue. Specifically, 3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the personalized titanium plates...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28765800/fortifying-the-bone-implant-interface-part-2-an-in-vivo-evaluation-of-3d-printed-and-tps-coated-triangular-implants
#10
Regina F MacBarb, Derek P Lindsey, Shane A Woods, Peggy A Lalor, Mukund I Gundanna, Scott A Yerby
BACKGROUND: Minimally invasive surgical fusion of the sacroiliac (SI) joint using machined solid triangular titanium plasma spray (TPS) coated implants has demonstrated positive clinical outcomes in SI joint pain patients. Additive manufactured (AM), i.e. 3D-printed, fenestrated triangular titanium implants with porous surfaces and bioactive agents, such as nanocrystalline hydroxyapatite (HA) or autograft, may further optimize bony fixation and subsequent biomechanical stability. METHODS: A bilateral ovine distal femoral defect model was used to evaluate the cancellous bone-implant interfaces of TPS-coated and AM implants...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28765799/fortifying-the-bone-implant-interface-part-1-an-in-vitro-evaluation-of-3d-printed-and-tps-porous-surfaces
#11
Regina F MacBarb, Derek P Lindsey, Chelsea S Bahney, Shane A Woods, Mark L Wolfe, Scott A Yerby
BACKGROUND: An aging society and concomitant rise in the incidence of impaired bone health have led to the need for advanced osteoconductive spinal implant surfaces that promote greater biological fixation (e.g. for interbody fusion cages, sacroiliac joint fusion implants, and artificial disc replacements). Additive manufacturing, i.e. 3D-printing, may improve bone integration by generating biomimetic spinal implant surfaces that mimic bone morphology. Such surfaces may foster an enhanced cellular response compared to traditional implant surfacing processes...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28761274/comparative-evaluation-of-bite-force-analytical-study-following-mandibular-osteosysthesis-using-three-dimensional-and-conventional-locking-miniplates
#12
Pallav Kumar Kinra, K Jayakumar, C S Soumithran, Manoj Joseph Michael, Deepak Passi, Mahinder Singh
AIMS AND OBJECTIVES: The aim is to study the effectiveness of 2 mm three-dimensional (3D) titanium miniplates and 2 mm conventional titanium miniplates in osteosynthesis of mandibular fractures by comparing the change in bite force. METHODOLOGY: The study comprised forty patients of age group 20-40 years, weighing 55-75 kg having mandibular fractures. Patients were randomly divided into two equal groups In Group A, twenty patients underwent osteosynthesis using 3D titanium miniplates (2...
January 2017: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28746140/are-there-3d-changes-in-spine-and-rod-shape-in-the-2-years-after-adolescent-idiopathic-scoliosis-instrumentation
#13
Franck Le Navéaux, Hubert Labelle, Stefan Parent, Peter O Newton, Carl-Eric Aubin
STUDY DESIGN: Retrospective analysis of spine and rods 3D shape in the 2 years after adolescent idiopathic scoliosis (AIS) posterior surgical instrumentation. OBJECTIVE: To evaluate spine and rod shape 3D changes in the 2 years after AIS instrumentation with different rod materials. SUMMARY OF BACKGROUND DATA: Postoperative loss of correction has been reported with modern segmental instrumentation. The postoperative 3D rod shape changes of different rod materials and their implication in postoperative loss of correction have never been studied...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28736922/effect-of-implantoplasty-on-fracture-resistance-and-surface-roughness-of-standard-diameter-dental-implants
#14
Xavier Costa-Berenguer, Marta García-García, Alba Sánchez-Torres, Mariano Sanz-Alonso, Rui Figueiredo, Eduard Valmaseda-Castellón
OBJECTIVE: To assess the effect of implantoplasty on the fracture resistance, surface roughness, and macroscopic morphology of standard diameter (4.1 mm) external connection dental implants. MATERIALS AND METHODS: An in vitro study was conducted in 20 screw-shaped titanium dental implants with an external connection. In 10 implants, the threads and surface were removed and polished with high-speed burs (implantoplasty), while the remaining 10 implants were used as controls...
July 23, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28720339/in%C3%A2-vitro-fit-of-cad-cam-complete-arch-screw-retained-titanium-and-zirconia-implant-prostheses-fabricated-on-4-implants
#15
Hadi Al-Meraikhi, Burak Yilmaz, Edwin McGlumphy, William Brantley, William M Johnston
STATEMENT OF PROBLEM: Computer-aided designed and computer-aided manufactured (CAD-CAM) titanium and zirconia implant-supported fixed implant prostheses on 4 implants have become popular. The precision and accuracy of their interface fit has not been widely researched. PURPOSE: The purpose of this in vitro study was to compare the marginal fit of zirconia and titanium implant-supported screw-retained CAD-CAM complete fixed dental prostheses (CFDP) fit with a standardized cast simulating the all-on-4 implant distribution...
July 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28689135/deformation-and-fatigue-of-tough-3d-printed-elastomer-scaffolds-processed-by-fused-deposition-modeling-and-continuous-liquid-interface-production
#16
Andrew T Miller, David L Safranski, Catherine Wood, Robert E Guldberg, Ken Gall
Polyurethane (PU) based elastomers continue to gain popularity in a variety of biomedical applications as compliant implant materials. In parallel, advancements in additive manufacturing continue to provide new opportunities for biomedical applications by enabling the creation of more complex architectures for tissue scaffolding and patient specific implants. The purpose of this study was to examine the effects of printed architecture on the monotonic and cyclic mechanical behavior of elastomeric PUs and to compare the structure-property relationship across two different printing approaches...
July 1, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28647748/single-level-anterior-cervical-corpectomy-and-fusion-using-a-new-3d-printed-anatomy-adaptive-titanium-mesh-cage-for-treatment-of-cervical-spondylotic-myelopathy-and-ossification-of-the-posterior-longitudinal-ligament-a-retrospective-case-series-study
#17
Teng Lu, Chao Liu, Baohui Yang, Jiantao Liu, Feng Zhang, Dong Wang, Haopeng Li, Xijing He
BACKGROUND The aim of this study was to evaluate the clinical and radiological outcomes of the use of a new 3D-printed anatomy-adaptive titanium mesh cage (AA-TMC) for single-level anterior cervical corpectomy and fusion (ACCF) in patients with cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL). MATERIAL AND METHODS We retrospectively reviewed the records of 15 consecutive patients who underwent ACCF surgeries with AA-TMC implantation. The Japanese Orthopedic Association (JOA) scoring system, a visual analogue scale (VAS), the mean intervertebral height (MIBH) of the surgical segments, and the surgical segmental angle (SSA) were recorded preoperatively, immediately after surgery and at the final follow-up visit...
June 25, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28645667/effect-of-different-restorative-crown-and-customized-abutment-materials-on-stress-distribution-in-single-implants-and-peripheral-bone-a-three-dimensional-finite-element-analysis-study
#18
Necati Kaleli, Duygu Sarac, Safak Külünk, Özgür Öztürk
STATEMENT OF PROBLEM: In recent years, the use of resin-matrix ceramics and polyetheretherketone (PEEK) abutments has been suggested to absorb excessive stresses on dental implants. However, only a few studies have evaluated the effect of these materials on stress distribution in implants and peripheral bone structure. PURPOSE: The purpose of this finite element analysis was to evaluate the biomechanical behaviors of resin-matrix ceramics and PEEK customized abutments in terms of stress distribution in implants and peripheral bone...
June 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28581710/biotransformation-of-silver-released-from-nanoparticle-coated-titanium-implants-revealed-in-regenerating-bone
#19
Hua Geng, Gowsihan Poologasundarampillai, Naomi Todd, Aine Devlin-Mullin, Katie L Moore, Zahra Golrokhi, James B Gilchrist, Eric Jones, Richard J Potter, Chris Sutcliffe, Marie O'Brien, David W L Hukins, Sarah Cartmell, Christopher A Mitchell, Peter D Lee
Antimicrobial silver nanoparticle coatings have attracted interest for reducing prosthetic joint infection. However, few studies report in vivo investigations of the biotransformation of silver nanoparticles within the regenerating tissue and its impact on bone formation. We present a longitudinal investigation of the osseointegration of silver nanoparticle-coated additive manufactured titanium implants in rat tibial defects. Correlative imaging at different time points using nanoscale secondary ion mass spectrometry, transmission electron microscopy (TEM), histomorphometry, and 3D X-ray microcomputed tomography provided quantitative insight from the nano- to macroscales...
June 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28578109/reconstruction-of-thoracic-spine-using-a-personalized-3d-printed-vertebral-body-in-adolescent-with-t9-primary-bone-tumor
#20
Wen Jie Choy, Ralph J Mobbs, Ben Wilcox, Steven Phan, Kevin Phan, Chester E Sutterlin
BACKGROUND: Neurosurgery and spine surgery have the potential to benefit from the use of 3-dimensional printing (3DP) technology due to complex anatomic considerations and the delicate nature of surrounding structures. We report a procedure that uses a 3D-printed titanium T9 vertebral body implant post T9 vertebrectomy for a primary bone tumor. CASE DESCRIPTION: A 14-year-old female presented with progressive kyphoscoliosis and a pathologic fracture of the T9 vertebra with sagittal and coronal deformity due to a destructive primary bone tumor...
September 2017: World Neurosurgery
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