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https://www.readbyqxmd.com/read/28634537/a-meta-analysis-of-antibacterial-envelope-use-in-prevention-of-cardiovascular-implantable-electronic-device-infection
#1
Sajid Ali, Yousuf Kanjwal, Steven R Bruhl, Mohammed Alo, Mohammed Taleb, Syed S Ali, Ameer Kabour, Owais Khawaja
OBJECTIVES: Cardiac implantable electronic device (CIED) infection has been a major clinical problem in addition to being a major financial burden. In spite of antimicrobial prophylaxis, CIED infection rates have been increasing disproportionately. We therefore conducted this meta-analysis to assess the role of TYRX antibiotic envelope for the prevention of CIED infection. METHODS: Using extensive online search, we conducted a meta-analysis of studies reporting CIED infections with versus without the use of TYRX antibiotic envelope...
May 2017: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/28605036/still-begging-for-a-solution-the-ongoing-problem-of-device-cied-infection
#2
EDITORIAL
Qi Zheng, John D Fisher
No abstract text is available yet for this article.
June 12, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28603001/low-lateral-thoracic-site-for-cardiac-implantable-electronic-device-implantation-a-viable-alternative-in-patients-with-limited-access-options-after-infected-device-extraction
#3
Jackson J Liang, Robert D Schaller, Danesh S Modi, Andres Enriquez, Gregory E Supple, Joshua M Cooper
BACKGROUND: Device reimplantation after extraction due to cardiac implantable electronic device (CIED) infection in pacemaker-dependent patients can be challenging in patients with limited access options. OBJECTIVE: We describe a straight-forward, low lateral thoracic implantation technique for patients with a patent axillary vein but unavailable bilateral pectoral sites. METHODS: We included 9 pacemaker-dependent patients (mean age 70±13, 7 male) who underwent CIED extraction and low lateral thoracic reimplant, in whom bilateral pectoral sites were unavailable...
June 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28602063/risk-factors-for-poor-prognosis-in-nosocomial-infective-endocarditis
#4
Ji-Won Hwang, Seung Woo Park, Eun Jeong Cho, Ga Yeon Lee, Eun Kyoung Kim, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song, Ji-Won Hwang, Seung Woo Park, Eun Jeong Cho, Ga Yeon Lee, Eun Kyoung Kim, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
Background/Aims: The aim of our study was to compare the characteristics of nosocomial infective endocarditis (NIE) with community-acquired infective endocarditis (CIE) and to determine independent risk factors for in-hospital death. Methods: We retrospectively reviewed the medical records of 560 patients diagnosed with infective endocarditis. NIE was defined by a diagnosis made > 72 hours after hospital admission or within 2 months of hospital discharge. Results: Among the 560 cases reviewed, 121 were classified as NIE...
June 2, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28594654/rationale-study-design-and-pilot-phase-of-the-management-of-antithrombotic-therapy-in-patients-undergoing-electrophysiological-device-surgery-italian-national-multicenter-observational-registry
#5
Valerio Zacà, Marco Breschi, Alberto Mandorli, Luca Panchetti, Giuseppe Ricciardi, Stefano Viani, Pasquale Notarstefano
AIMS: To investigate the different strategies adopted for the management of antithrombotic therapy and the related hemorrhagic and infective complication rates in patients undergoing cardiac implantable electronic devices (CIEDs) surgery in a real-world setting. METHODS: THE Management of AntiThrOMbotic therApy in patients undergoing electrophysiological device surgery: Italian NatiOnal Multicenter Observational REgistry (HEMATOMA NO MORE) is an observational, prospective, multicenter, national cohort study (with a retrospective, multicenter, regional pilot phase) designed to enroll patients with standard indications to CIED implantations/replacements receiving concomitant antithrombotic therapy...
June 7, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28582500/comparison-of-epicardial-vs-endocardial-reimplantation-in-pacemaker-dependent-patients-with-device-infection
#6
Tilman Perrin, Baptiste Maille, Coralie Lemoine, Noémie Resseguier, Frédéric Franceschi, Linda Koutbi, Jérôme Hourdain, Jean-Claude Deharo
Aims: Reimplantation of cardiac implantable electronic devices (CIEDs) after extraction due to device infection is a major issue in pacemaker-dependent patients. We compared in-hospital and long-term outcomes with two techniques: epicardial reimplantation (EPI) before CIED extraction and temporary pacing (TP) with a view to delayed endocardial reimplantation. Methods and results: Two cohorts of consecutive pacemaker-dependent patients who underwent transvenous lead extraction at our tertiary centre were included in this retrospective cohort study...
June 3, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28544152/a-risk-adapted-approach-to-treating-respiratory-syncytial-virus-and-human-parainfluenza-virus-in-allogeneic-stem-cell-transplantation-recipients-with-oral-ribavirin-therapy-a-pilot-study
#7
José Luis Piñana, Juan Carlos Hernández-Boluda, Marisa Calabuig, Isabel Ballester, Manuela Marín, Silvia Madrid, Anabel Teruel, María-José Terol, David Navarro, Carlos Solano
Here we report the applicability of a protocol based on clinical conditions and risk factors (RFs) for managing 35 allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients who developed a total of 52 episodes of respiratory viral infections (RVIs) caused by respiratory syncytial virus (RSV; n=19), human parainfluenza virus (HPIV; n=29), or both (n=4) over a 2-year study period. Risk categories were classified as high risk (cat-1) when the immunodeficiency scoring index) was ≥ 3 and/or ≥ 3 RFs and/or ≥ 1 co-infective virus(es) were present; the remaining cases were classified as low risk (cat-0)...
May 19, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28526307/risk-factors-of-cardiac-device-infection-glove-contamination-during-device-procedures
#8
Isabella Kozon, Sam Riahi, Søren Lundbye-Christensen, Anna Margrethe Thøgersen, Tove Ejlertsen, Dorthe Aaen, Kirsten I Paulsen, Søren Hjortshøj
BACKGROUND: Infections in cardiac implantable electronic devices (CIEDs) constitute a serious complication. We sought to identify contamination of gloves before handling the device in primary and replacement CIED procedures. METHODS: Two groups of 30 patients underwent primary CIED implantation or replacement. Before the device entered the surgical field, surgeon and assistant imprinted their outer gloves on aerobe and anaerobe agar plates, and a wound swab was performed...
May 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28521596/overcoming-the-current-issues-surrounding-device-leads-reducing-the-complications-during-extraction
#9
Maria Grazia Bongiorni, Luca Segreti, Andrea Di Cori, Giulio Zucchelli, Luca Paperini, Stefano Viani, Ezio Soldati
The implantation rate of cardiac implantable electronic devices has consistently increased in the last 20 years, as have the related complication rates. The most relevant issue is the removal of pacing and implantable cardioverter defibrillator (ICD) leads, which a few months after implantation tend to develop intravascular fibrosis, often making extraction a challenging and risky procedure. Areas covered: The transvenous lead extraction (TLE) scenario is constantly evolving. TLE is a key procedure in lead management strategies...
June 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28496930/percutaneous-vacuum-assisted-thrombectomy-device-used-for-removal-of-large-vegetations-on-infected-pacemaker-and-defibrillator-leads-as-an-adjunct-to-lead-extraction
#10
Raymond H M Schaerf, Sasan Najibi, John Conrad
This case series reports our early experience with a minimally invasive percutaneous method of safely removing large vegetations during lead extraction in septic cardiac implantable electronic devices (CIED). Debate exists concerning the management of vegetations involving these devices. Lead extraction is mandated for infections, but vegetations may embolize, causing complications. Surgical debridement is recommended; alternatives include cardiopulmonary bypass, minimally invasive thoracotomy, or transatrial approaches...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28454777/identification-of-causative-organism-in-cardiac-implantable-electronic-device-infections
#11
Masato Fukunaga, Masahiko Goya, Michio Nagashima, Kenichi Hiroshima, Takashi Yamada, Yoshimori An, Kentaro Hayashi, Yu Makihara, Masatsugu Ohe, Kei Ichihashi, Morimasa Ohtsuka, Hiroaki Miyazaki, Kenji Ando
BACKGROUND: The causative organism in cardiovascular implantable electronic device (CIED) infection is usually diagnosed with the cultures from blood, removed leads, and/or infected pocket material. The cultured organism, however, is sometimes different among these samples. METHODS: Two hundred sixty patients with CIED infection, who underwent lead extraction between April 2005 and December 2014, were analyzed. More than two blood culture sets, all the extracted leads, and swab culture of the pocket were sent to the laboratory for culture...
April 25, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28434707/in-hospital-complications-after-implantation-of-cardiac-implantable-electronic-devices-analysis-of-a-national-inpatient-database-in-japan
#12
Sandeep Shakya, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
BACKGROUND: Complications after implantation of cardiac implantable electronic devices (CIEDs), including permanent pacemakers (PMs) and other CIEDs, are associated with increased patient mortality and healthcare costs. This study aimed to investigate overall complications after implantation of CIEDs, analyze the associated risk factors, and compare complications after PM implantation between hospitals that performed only PM implantations (PM-only hospitals) and hospitals that implanted other CIEDs, as well as PMs (all-CIED hospitals)...
April 20, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28434261/strategies-to-prevent-infections-associated-with-cardiovascular-implantable-electronic-devices
#13
Bharath Raj Palraj, Saira Farid, M Rizwan Sohail
Infections involving cardiovascular implantable electronic devices (CIED) are associated with high morbidity and mortality and substantial financial cost. In the past two decades, the rate of CIED infections has increased disproportionate to the number of devices implanted, likely due to aging patient population with multiple comorbidities. Microbial contamination of the generator pocket and or leads by skin flora at the time of implantation is a major mechanism for early CIED infections. Due to resistance to host immune cells and antibiotics caused by biofilm formation, complete removal of the device generator and leads is required to achieve cure...
May 4, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28377468/positron-emission-tomography-and-single-photon-emission-computed-tomography-imaging-in-the-diagnosis-of-cardiac-implantable-electronic-device-infection-a-systematic-review-and-meta-analysis
#14
REVIEW
Daniel Juneau, Mohammad Golfam, Samir Hazra, Lionel S Zuckier, Shady Garas, Calum Redpath, Jordan Bernick, Eugene Leung, Sharon Chih, George Wells, Rob S B Beanlands, Benjamin J W Chow
BACKGROUND: The use of cardiac implantable electronic devices (CIED) is increasing, and their associated infections result in significant morbidity and mortality. The introduction of better cardiac imaging techniques could be useful for diagnosing this condition and guiding therapy. Our objective was to systematically assess the diagnostic accuracy of Fluor-18-fluorodeoxyglucose positron emission tomography and computed tomography, labeled leukocyte scintigraphy (LS), and Gallium-67 citrate scintigraphy for the diagnosis of CIED infection...
April 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28337084/therapeutic-drug-monitoring-of-continuous-infusion-doripenem-in-a-pediatric-patient-on-continuous-renal-replacement-therapy
#15
Jeffrey J Cies, Wayne S Moore, Susan B Conley, Paul Shea, Adela Enache, Arun Chopra
An 11-year-old African American male with severe combined immunodeficiency variant, non-cystic fibrosis bronchiectasis, pancreatic insufficiency, chronic mycobacterium avium-intracellulare infection, chronic sinusitis, and malnutrition presented with a 1-week history of fevers. He subsequently developed respiratory decompensation and cefepime was discontinued and doripenem was initiated. Doripenem was the carbapenem used due to a national shortage of meropenem. By day 7 the patient (24.7 kg) had a positive fluid balance of 6925 mL (28% FO), and on days 7 into 8 developed acute kidney injury evidenced by an elevated serum creatinine of 0...
January 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28337082/pharmacokinetics-of-peramivir-in-an-adolescent-patient-receiving-continuous-venovenous-hemodiafiltration
#16
Ryan C Dillon, Robert Witcher, Jeffrey J Cies, Wayne S Moore, Arun Chopra
Critically ill patients requiring renal replacement therapy commonly experience pharmacokinetic alterations. This case report describes the pharmacokinetics of peramivir (Rapivab, BioCryst Pharmaceuticals, Inc, Durham, NC), the first US Food and Drug Administration-approved intravenous neuraminidase inhibitor for the treatment of influenza, in an adolescent patient receiving continuous renal replacement therapy (CRRT). A 49.5-kg, 17-year-old Caucasian female presented with fever, cough, and persistent hypoxia...
January 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28329125/outcomes-in-patients-with-cardiovascular-implantable-electronic-device-infection-managed-with-chronic-antibiotic-suppression
#17
Eugene M Tan, Daniel C DeSimone, M Rizwan Sohail, Larry M Baddour, Walter R Wilson, James M Steckelberg, Abinash Virk
Background.: Most cardiovascular implantable electronic device (CIED) recipients are elderly, have multiple comorbid conditions, and are at increased risk of CIED infection (CIEDI). Current guidelines recommend complete device removal in patients with CIEDI to prevent relapse and mortality. However, comorbidities or other factors may preclude device removal, thus prompting a nonsurgical approach that includes chronic antibiotic suppression (CAS). There are limited data on outcomes of patients receiving CAS for CIEDI...
June 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28321212/microbiological-characteristics-and-clinical-features-of-cardiac-implantable-electronic-device-infections-at-a-tertiary-hospital-in-china
#18
Ruobing Wang, Xuebin Li, Qi Wang, Yawei Zhang, Hui Wang
The incidence of cardiac implantable electronic device (CIED) infections is rapidly increasing worldwide. However, the microbiological characteristics and clinical features of symptomatic CIED infections are not well described. The present study included patients with CIED infections in China, and their pocket tissues were collected for clinical microbiological determination. A total of 219 patients with CIED infections were investigated; of these patients, 145 (66.2%) were positive for CIED infection in pocket tissue cultures and 24 (11...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28315744/cardiac-implantable-electronic-device-infections-who-is-at-greatest-risk
#19
Parijat Saurav Joy, Gagan Kumar, Jeanne E Poole, Barry London, Brian Olshansky
BACKGROUND: Cardiac implantable electronic device (CIED) infections are associated with hospitalization, mortality, increased costs, and adverse outcomes. OBJECTIVE: Determine the burden of infections for CIEDs based on device type, associated comorbidities, and clinical characteristics over a 12-year period. METHODS: Utilizing data from the National Inpatient Sample database for cases from 2000 through 2012, we identified procedures for device-related infection (DRI) using International Statistical Classification of Diseases and Related Health Problems, Ninth Revision, Clinical Modification (ICD-9-CM) codes for CIED removal with diagnosis codes for device-related infection or systemic infection...
March 16, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28264059/biomarker-based-diagnosis-of-pacemaker-and-implantable-cardioverter-defibrillator-pocket-infections-a-prospective-multicentre-case-control-evaluation
#20
Carsten Lennerz, Hrvoje Vrazic, Bernhard Haller, Siegmund Braun, Tobias Petzold, Ilka Ott, Agnes Lennerz, Jonathan Michel, Patrick Blažek, Isabel Deisenhofer, Peter Whittaker, Christof Kolb
BACKGROUND: The use of cardiac implantable electronic devices (CIED) has risen steadily, yet the rate of cardiac device infections (CDI) has disproportionately increased. Amongst all cardiac device infections, the pocket infection is the most challenging diagnosis. Therefore, we aimed to improve diagnosis of such pocket infection by identifying relevant biomarkers. METHODS: We enrolled 25 consecutive patients with invasively and microbiologically confirmed pocket infection...
2017: PloS One
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