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https://www.readbyqxmd.com/read/28434707/in-hospital-complications-after-implantation-of-cardiac-implantable-electronic-devices-analysis-of-a-national-inpatient-database-in-japan
#1
Sandeep Shakya, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
BACKGROUND: Complications after implantation of cardiac implantable electronic devices (CIEDs), including permanent pacemakers (PMs) and other CIEDs, are associated with increased patient mortality and healthcare costs. This study aimed to investigate overall complications after implantation of CIEDs, analyze the associated risk factors, and compare complications after PM implantation between hospitals that performed only PM implantations (PM-only hospitals) and hospitals that implanted other CIEDs, as well as PMs (all-CIED hospitals)...
April 20, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28434261/strategies-to-prevent-infections-associated-with-cardiovascular-implantable-electronic-devices
#2
Bharath Raj Palraj, Saira Farid, M Rizwan Sohail
Infections involving cardiovascular implantable electronic devices (CIED) are associated with high morbidity and mortality and substantial financial cost. In the past two decades, the rate of CIED infections has increased disproportionate to the number of devices implanted, likely due to aging patient population with multiple comorbidities. Microbial contamination of the generator pocket and or leads by skin flora at the time of implantation is a major mechanism for early CIED infections. Due to resistance to host immune cells and antibiotics caused by biofilm formation, complete removal of the device generator and leads is required to achieve cure...
April 24, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28377468/positron-emission-tomography-and-single-photon-emission-computed-tomography-imaging-in-the-diagnosis-of-cardiac-implantable-electronic-device-infection-a-systematic-review-and-meta-analysis
#3
Daniel Juneau, Mohammad Golfam, Samir Hazra, Lionel S Zuckier, Shady Garas, Calum Redpath, Jordan Bernick, Eugene Leung, Sharon Chih, George Wells, Rob S B Beanlands, Benjamin J W Chow
BACKGROUND: The use of cardiac implantable electronic devices (CIED) is increasing, and their associated infections result in significant morbidity and mortality. The introduction of better cardiac imaging techniques could be useful for diagnosing this condition and guiding therapy. Our objective was to systematically assess the diagnostic accuracy of Fluor-18-fluorodeoxyglucose positron emission tomography and computed tomography, labeled leukocyte scintigraphy (LS), and Gallium-67 citrate scintigraphy for the diagnosis of CIED infection...
April 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28337084/therapeutic-drug-monitoring-of-continuous-infusion-doripenem-in-a-pediatric-patient-on-continuous-renal-replacement-therapy
#4
Jeffrey J Cies, Wayne S Moore, Susan B Conley, Paul Shea, Adela Enache, Arun Chopra
An 11-year-old African American male with severe combined immunodeficiency variant, non-cystic fibrosis bronchiectasis, pancreatic insufficiency, chronic mycobacterium avium-intracellulare infection, chronic sinusitis, and malnutrition presented with a 1-week history of fevers. He subsequently developed respiratory decompensation and cefepime was discontinued and doripenem was initiated. Doripenem was the carbapenem used due to a national shortage of meropenem. By day 7 the patient (24.7 kg) had a positive fluid balance of 6925 mL (28% FO), and on days 7 into 8 developed acute kidney injury evidenced by an elevated serum creatinine of 0...
January 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28337082/pharmacokinetics-of-peramivir-in-an-adolescent-patient-receiving-continuous-venovenous-hemodiafiltration
#5
Ryan C Dillon, Robert Witcher, Jeffrey J Cies, Wayne S Moore, Arun Chopra
Critically ill patients requiring renal replacement therapy commonly experience pharmacokinetic alterations. This case report describes the pharmacokinetics of peramivir (Rapivab, BioCryst Pharmaceuticals, Inc, Durham, NC), the first US Food and Drug Administration-approved intravenous neuraminidase inhibitor for the treatment of influenza, in an adolescent patient receiving continuous renal replacement therapy (CRRT). A 49.5-kg, 17-year-old Caucasian female presented with fever, cough, and persistent hypoxia...
January 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28329125/outcomes-in-patients-with-cardiovascular-implantable-electronic-device-infection-managed-with-chronic-antibiotic-suppression
#6
Eugene M Tan, Daniel C DeSimone, M Rizwan Sohail, Larry M Baddour, Walter R Wilson, James M Steckelberg, Abinash Virk
Background: Most cardiovascular implantable electronic device (CIED) recipients are elderly, have multiple comorbid conditions, and are at increased risk of CIED infection (CIEDI). Current guidelines recommend complete device removal in patients with CIEDI to prevent relapse and mortality. However, comorbidities or other factors may preclude device removal, thus prompting a non-surgical approach that includes chronic antibiotic suppression (CAS). There are limited data on outcomes of patients receiving CAS for CIEDI...
February 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28321212/microbiological-characteristics-and-clinical-features-of-cardiac-implantable-electronic-device-infections-at-a-tertiary-hospital-in-china
#7
Ruobing Wang, Xuebin Li, Qi Wang, Yawei Zhang, Hui Wang
The incidence of cardiac implantable electronic device (CIED) infections is rapidly increasing worldwide. However, the microbiological characteristics and clinical features of symptomatic CIED infections are not well described. The present study included patients with CIED infections in China, and their pocket tissues were collected for clinical microbiological determination. A total of 219 patients with CIED infections were investigated; of these patients, 145 (66.2%) were positive for CIED infection in pocket tissue cultures and 24 (11...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28315744/cardiac-implantable-electronic-device-infections-who-is-at-greatest-risk
#8
Parijat Saurav Joy, Gagan Kumar, Jeanne E Poole, Barry London, Brian Olshansky
BACKGROUND: Cardiac implantable electronic device (CIED) infections are associated with hospitalization, mortality, increased costs, and adverse outcomes. OBJECTIVE: Determine the burden of infections for CIEDs based on device type, associated comorbidities, and clinical characteristics over a 12-year period. METHODS: Utilizing data from the National Inpatient Sample database for cases from 2000 through 2012, we identified procedures for device-related infection (DRI) using International Statistical Classification of Diseases and Related Health Problems, Ninth Revision, Clinical Modification (ICD-9-CM) codes for CIED removal with diagnosis codes for device-related infection or systemic infection...
March 16, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28264059/biomarker-based-diagnosis-of-pacemaker-and-implantable-cardioverter-defibrillator-pocket-infections-a-prospective-multicentre-case-control-evaluation
#9
Carsten Lennerz, Hrvoje Vrazic, Bernhard Haller, Siegmund Braun, Tobias Petzold, Ilka Ott, Agnes Lennerz, Jonathan Michel, Patrick Blažek, Isabel Deisenhofer, Peter Whittaker, Christof Kolb
BACKGROUND: The use of cardiac implantable electronic devices (CIED) has risen steadily, yet the rate of cardiac device infections (CDI) has disproportionately increased. Amongst all cardiac device infections, the pocket infection is the most challenging diagnosis. Therefore, we aimed to improve diagnosis of such pocket infection by identifying relevant biomarkers. METHODS: We enrolled 25 consecutive patients with invasively and microbiologically confirmed pocket infection...
2017: PloS One
https://www.readbyqxmd.com/read/28240419/enhanced-antimicrobial-effects-of-decellularized-extracellular-matrix-cormatrix-with-added-vancomycin-and-gentamicin-for-device-implant-protection
#10
Thomas F Deering, Carlos Chang, Carl Snyder, Selvamuthu K Natarajan, Robert Matheny
BACKGROUND: The incidence of cardiac implantable electronic device (CIED) infections has risen significantly over the past years. Although several devices are currently available to decrease the incidence of infection, most are made from non-viable synthetic material and are more prone to infection than vascularized tissue. OBJECTIVE: This study was undertaken to assess the resistance to infection of the CorMatrix CanGaroo, a CIED envelope made of decellularised extracellular matrix (ECM) hydrated in different antibiotic solutions...
February 27, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28194345/transaxillary-subpectoral-placement-of-cardiac-implantable-electronic-devices-in-young-female-patients
#11
Joo Hyun Oh, Chae Min Kim, Seung Yong Song, Jae Sun Uhm, Dae Hyun Lew, Dong Won Lee
BACKGROUND: The current indications of cardiac implantable electronic devices (CIEDs) have expanded to include young patients with serious cardiac risk factors, but CIED placement has the disadvantage of involving unsightly scarring and bulging of the chest wall. A collaborative team of cardiologists and plastic surgeons developed a technique for the subpectoral placement of CIEDs in young female patients via a transaxillary approach. METHODS: From July 2012 to December 2015, subpectoral CIED placement via an axillary incision was performed in 10 young female patients, with a mean age of 25...
January 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28131641/retrospective-comparative-analysis-of-cardiovascular-implantable-electronic-device-infections-with-and-without-the-use-of-antibacterial-envelopes
#12
COMPARATIVE STUDY
A Hassoun, E D Thottacherry, M Raja, M Scully, A Azarbal
BACKGROUND: Cardiovascular implantable electronic device (CIED) infections are associated with morbidity and mortality. Peri-operative systemic intravenous antibiotic prophylaxis reduces the rate of CIED infections. AIGISRx, a polymer envelope implanted with the CIED, releases minocycline and rifampin, and has been introduced to reduce infections. METHODS: Retrospective review of 184 patients who underwent CIED implantation was conducted. Ninety-two patients were implanted with an AIGISRx envelope (AIGISRx group) and 92 patients were not implanted with an AIGISRx envelope (control group)...
March 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28111362/incidence-of-bleeding-related-complications-during-primary-implantation-and-replacement-of-cardiac-implantable-electronic-devices
#13
Christine I Nichols, Joshua G Vose
BACKGROUND: Use of cardiac implantable electronic devices (CIEDs) is increasing. The incidence of bleeding-related complications during CIED procedures and the association with subsequent infection risk have been studied in trial settings but not in nonrandomized "real-world" populations. METHODS AND RESULTS: This retrospective database analysis of US insurance claims from the Truven MarketScan database (2009-2013) evaluated the incidence of bleeding complications during, or in the 30 days following, a CIED procedure and the association between bleeding and subsequent infection in days 31 to 365 of follow-up...
January 22, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28073883/infective-endocarditis-and-risk-of-death-after-cardiac-implantable-electronic-device-implantation-a-nationwide-cohort-study
#14
Cengiz Özcan, Jakob Raunsø, Morten Lamberts, Lars Køber, Tommi Bo Lindhardt, Niels Eske Bruun, Marie Louise Laursen, Christian Torp-Pedersen, Gunnar Hilmar Gislason, Morten Lock Hansen
AIMS: To determine the incidence, risk factors, and mortality of infective endocarditis (IE) following implantation of a first-time, permanent, cardiac implantable electronic device (CIED). METHODS AND RESULTS: From Danish nationwide administrative registers (beginning in 1996), we identified all de-novo permanent pacemakers (PMs) and implantable cardioverter defibrillators (ICDs) together with the occurrence of post-implantation IE-events in the period from 2000-2012...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27996097/prevention-of-cardiac-implantable-electronic-device-infections-single-operator-technique-with-use-of-povidone-iodine-double-gloving-meticulous-aseptic-antiseptic-measures-and-antibiotic-prophylaxis
#15
Antonis S Manolis, Helen Melita
BACKGROUND: Cardiac implantable electronic device (CIED) implantation is complicated by infection still at a worrisome rate of 2-5%. Since early on during device implantation procedures, we have adopted an infection-preventive technique which has hitherto resulted in effective prevention of infections. Herein we present our results of applying this technique by a single operator in a prospective series of 762 consecutive patients undergoing device implantation. METHODS: A meticulous search for and treatment of active, occult, or smoldering infection was undertaken preoperatively...
January 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27941400/lead-extraction-considerations-for-the-referring-cardiologist
#16
Ayman Hussein, Bruce L Wilkoff
The population of patients with cardiac implantable electronic devices (CIED) continues to grow owing to increasing indications in an aging population and breakthroughs in both the medical and surgical care of patients with heart disease. In clinical practice there has been a growing need for device and lead extraction due to the growing population of patients with CIEDs and the subsequent need for system upgrades or revisions because of complications, infections and lead advisory alerts. In this condensed review, we will discuss aspects of transvenous lead extraction, with a special focus on considerations that would be relevant to the referring cardiologist...
November 17, 2016: Cardiology in Review
https://www.readbyqxmd.com/read/27850287/648-utility-of-procalcitonin-for-viral-lower-respiratory-tract-infections-in-the-pediatric-icu
#17
John Kotula, Wayne Moore, Arun Chopra, Jeffrey Cies
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27830083/the-seroprevalence-of-human-cystic-echinococcosis-in-iran-a-systematic-review-and-meta-analysis-study
#18
REVIEW
Reza Shafiei, Saeed Hosseini Teshnizi, Kurosh Kalantar, Maryam Gholami, Golnush Mirzaee, Fatemeh Mirzaee
Human cystic echinococcosis (HCE), a zoonotic infection of the larval stage of Echinococcus granulosus, has high effect on public health in human population all around the world. Iran is one of the most important endemic areas in the Middle East. This systematic review and meta-analysis was performed to evaluate the seroprevalence of HCE in Iranian population. An electronic search for articles from 1985 until April 2015 was performed using data bases PubMed, Scopus, Google Scholar, Magiran, IranMedex, Iran Doc, and Scientific Information Database (SID) both in English and in Persian...
2016: Journal of Parasitology Research
https://www.readbyqxmd.com/read/27721936/role-of-radionuclide-imaging-for-diagnosis-of-device-and-prosthetic-valve-infections
#19
REVIEW
Jean-François Sarrazin, François Philippon, Mikaël Trottier, Michel Tessier
Cardiovascular implantable electronic device (CIED) infection and prosthetic valve endocarditis (PVE) remain a diagnostic challenge. Cardiac imaging plays an important role in the diagnosis and management of patients with CIED infection or PVE. Over the past few years, cardiac radionuclide imaging has gained a key role in the diagnosis of these patients, and in assessing the need for surgery, mainly in the most difficult cases. Both (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) and radiolabelled white blood cell single-photon emission computed tomography/computed tomography (WBC SPECT/CT) have been studied in these situations...
September 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/27714592/characteristics-of-cefazolin-inoculum-effect-positive-methicillin-susceptible-staphylococcus-aureus-infection-in-a-multicentre-bacteraemia-cohort
#20
MULTICENTER STUDY
K-H Song, S-I Jung, S Lee, S Park, S M Kiem, S H Lee, Y G Kwak, Y K Kim, H-C Jang, Y-S Kim, H-I Kim, C J Kim, K-H Park, N J Kim, M-D Oh, H B Kim
Cefazolin treatment failure has been observed in high-inoculum infections caused by methicillin-susceptible Staphylococcus aureus (MSSA) with a cefazolin inoculum effect (CIE). However, data on the characteristics and risk factors for the acquisition of CIE-positive MSSA infection are scarce. CIE positivity was measured as an MIC ≥ 16 μg/ml with a high inoculum (∼5 × 10(7) CFU/ml). The blaZ gene type was assessed through sequence analysis. The clinical characteristics and risk factors for the acquisition of CIE-positive MSSA infection were assessed...
February 2017: European Journal of Clinical Microbiology & Infectious Diseases
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