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https://www.readbyqxmd.com/read/29799067/recommendations-on-nuclear-and-multimodality-imaging-in-ie-and-cied-infections
#1
Paola Anna Erba, Patrizio Lancellotti, Isidre Vilacosta, Oliver Gaemperli, Francois Rouzet, Marcus Hacker, Alberto Signore, Riemer H J A Slart, Gilbert Habib
In the latest update of the European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE), imaging is positioned at the centre of the diagnostic work-up so that an early and accurate diagnosis can be reached. Besides echocardiography, contrast-enhanced CT (ce-CT), radiolabelled leucocyte (white blood cell, WBC) SPECT/CT and [18 F]FDG PET/CT are included as diagnostic tools in the diagnostic flow chart for IE. Following the clinical guidelines that provided a straightforward message on the role of multimodality imaging, we believe that it is highly relevant to produce specific recommendations on nuclear multimodality imaging in IE and cardiac implantable electronic device infections...
May 24, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29796277/facial-flushing-on-upper-limb-exertion-a-rare-presentation-of-superior-vena-cava-obstruction
#2
Michael Plunkett, James Wethasinghe, Brendon O'Donoghue, Nigel Lever, Conroy Wong
Infection remains a significant problem for patients with cardiac-implantable electronic devices (CIEDs) but can be difficult to diagnose. We describe an unusual presentation of CIED infection in a patient with abandoned pacemaker leads. A 27-year-old male presented with facial flushing on upper but not lower limb exertion due to superior vena cava (SVC) obstruction, as well as pleuritic chest pain due to septic emboli. This was successfully treated with antibiotics and complete endovascular extraction of the pacemaker leads...
April 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29785752/skin-lesions-over-the-pocket-area-that-may-mimic-cardiac-implantable-electronic-device-infection-a-case-series
#3
Panagiotis Korantzopoulos, Sofia Plakoutsi, Elizabeth Florou, Aris Bechlioulis
BACKGROUND: The early and correct diagnosis of cardiac implantable electronic device (CIED) infections is critical given that early aggressive treatment with complete removal of the system along with antimicrobial therapy dramatically improves outcomes. Pocket infection manifested by local signs of inflammation is the most common form of CIED infections. Conditions mimicking pocket infection have been described in the literature. These include various types of malignancy and rarely allergic reactions/contact dermatitis to pacemaker compounds...
May 21, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29780757/huge-candida-albicans-normal-native-tricuspid-valve-endocarditis
#4
Massimiliano Guerriero, Francesco Colasurdo, Anna Maria Pollio
Fungal endocarditis has become an important infection associated with medical progress and the modern lifestyle. In particular, Candida spp. is a rare but important cause of infective endocarditis. We report the case of a 28-year-old woman-quadriplegic and bedridden from birth-who died after repeated episodes of pneumonia treated with different regimens of intravenous antibiotics. A medico legal autopsy was performed, which diagnosed severe Candida native valve infective endocarditis (CIE). This case report illustrates the prolonged use of antibiotic treatment as a possible risk factor for the development of CIE...
April 2018: Autopsy & Case Reports
https://www.readbyqxmd.com/read/29764229/use-of-surgical-hemostatic-powder-for-ep-device-implantation-reduces-postoperative-rates-of-pocket-hematoma-and-infection
#5
Olga Reynbakh, Philippe Akhrass, Nektarios Souvaliotis, Chaithanya K Pamidimukala, Hasnun Nahar, Joseph Bastawrose, Pierre Boktor, Joshua E Aziz, Davendra Mehta, Emad F Aziz
BACKGROUND: Surgical site bleeding and infection are potential complications after EP device implantation procedures. To date, there is a wide variety of tools for management of intraoperative bleeding but it still remains unclear what methods are preferred. OBJECTIVE: The aim of our study is to compare the rate of complications in patients who underwent Cardiac Implantable Electronic devices (CIED) implantation utilizing Arista as a hemostatic agent to the rate of complications in those patients who underwent standard procedure protocol without Arista...
May 15, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29759500/antibacterial-envelope-is-associated-with-low-infection-rates-after-implantable-cardioverter-defibrillator-and-cardiac-resynchronization-therapy-device-replacement-results-of-the-citadel-and-centurion-studies
#6
Charles A Henrikson, M Rizwan Sohail, Helbert Acosta, Eric E Johnson, Lawrence Rosenthal, Roman Pachulski, Dan Dan, Walter Paladino, Farhat S Khairallah, Kent Gleed, Ibrahim Hanna, Alan Cheng, Daniel R Lexcen, Grant R Simons
OBJECTIVES: This study sought to determine whether the nonabsorbable TYRX Antibacterial Envelope (TYRX) reduces major cardiovascular implantable electronic device (CIED) infections 12 months after implant. BACKGROUND: TYRX is a monofilament polypropylene mesh impregnated with minocycline and rifampin specifically designed to hold a CIED in place and elute antimicrobials over time. There are limited data on its ability to reduce CIED infections. METHODS: We prospectively enrolled patients who underwent generator replacement with an implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy device (CRT), treated with TYRX...
October 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29755632/is-there-always-a-need-for-permanent-pacemaker-replacement-after-device-infection-a-tale-of-two-patients
#7
Munish Sharma, Daniel A N Mascarenhas
There has been an increase in number of cardiac implantable electronic devices (CIEDs) implantation and with this we have witnessed increased rates of CIED infection mainly in elderly population. It is important to assess conditions that may not reliably improve with cardiac pacing or those who lack adequate beneficial effect from permanent pacing before contemplating implantation or reimplantation of these devices. Sometimes, the initial cardiac pathology may revert obviating the need for reimplantation as in the two cases that we have discussed below...
April 2018: Cardiology Research
https://www.readbyqxmd.com/read/29749938/impact-of-abandoned-leads-on-cardiovascular-implantable-electronic-device-infections-a-propensity-matched-analysis-of-medic-multicenter-electrophysiologic-device-infection-cohort
#8
Thomas A Boyle, Daniel Z Uslan, Jordan M Prutkin, Arnold J Greenspon, Larry M Baddour, Stephan B Danik, Jose M Tolosana, Katherine Le, Jose M Miro, James E Peacock, Muhammad R Sohail, Holenarasipur R Vikram, Roger G Carrillo
OBJECTIVES: This study sought to evaluate the impact of abandoned cardiovascular implantable electronic device (CIED) leads on the presentation and management of device-related infections. BACKGROUND: Device infection is a serious consequence of CIEDs and necessitates removal of all hardware for attempted cure. The merits of extracting or retaining presumed sterile but nonfunctioning leads is a subject of ongoing debate. METHODS: The MEDIC (Multicenter Electrophysiologic Device Infection Cohort) prospectively enrolled patients with CIED infections at 10 institutions in the United States and abroad between January 1, 2009, and December 31, 2012...
February 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29721118/temporary-external-implantable-cardioverter-defibrillator-as-a-bridge-to-reimplantation-after-infected-device-extraction
#9
Maciej Dębski, Andrzej Ząbek, Krzysztof Boczar, Małgorzata Urbańczyk-Zawadzka, Jacek Lelakowski, Barbara Małecka
Patients with cardiac implantable electronic devices (CIED) and endovascular infection represent a difficult management group. The explantation of an implantable cardioverter-defibrillator (ICD) system deprives the patient of the protection against life-threatening ventricular tachyarrhythmias. In this study, we describe feasibility and clinical outcomes of bridging with temporary dual-coil ICD lead and external ICD following the extraction of a CIED due to endovascular infection and compare the performance of this approach to other available options...
February 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29695526/approach-to-diagnosis-of-cardiovascular-implantable-electronic-device-infection
#10
Daniel C DeSimone, M Rizwan Sohail
Device infection remains a significant challenge as clinical indications for cardiovascular implantable electronic devices (CIED) therapy continue to expand beyond prevention and treatment of cardiac arrhythmias. Patients receiving CIED therapy are now older with significant comorbidities, placing them at higher risk of complications including infection. CIED infection warrants complete device removal as retention is associated with unacceptably high risk of relapse and increased mortality. However, accurate diagnosis of CIED infections remains a significant challenge and is based on a combination of findings on physical examination, microbiological and laboratory testing, and advanced imaging such as transesophageal echocardiography or positron emission tomography...
April 25, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29692938/a-case-of-pacemaker-endocarditis-caused-by-aerococcus-urinae
#11
Sandra Samuelsson, Charles Kennergren, Magnus Rasmussen
Background: Aerococcus urinae has lately been acknowledged as a cause of infective endocarditis (IE) especially in older males with underlying urinary tract disorders. In this population, cardiac implanted electronical devices (CIED) are not uncommon, but despite the capacity of A. urinae to form biofilm in vitro , no cases of aerococcal CIED infections have been reported to date. Case Presentation: An 84-year-old male with pacemaker was admitted with dysuria one month after a transurethral procedure for urinary bladder cancer...
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29672690/infections-and-associated-costs-following-cardiovascular-implantable-electronic-device-implantations-a-nationwide-cohort-study
#12
Nicolas Clémenty, Phuong Lien Carion, Lucie de Léotoing, Ludovic Lamarsalle, Fanny Wilquin-Bequet, Benedict Brown, Koen J P Verhees, Jérôme Fernandes, Jean-Claude Deharo
Aims: This study assessed the contemporary occurrence of cardiac device infections (CDIs) following implantation in French hospitals and estimated associated costs. Methods and Results: A retrospective analysis was conducted on the French National Hospital Database (PMSI). Patients with a record of de novo cardiac implantable electronic device (CIED) implantation or replacement interventions in France in 2012 were identified and followed until the end of 2015. Cardiac device infections (CDIs) were identified based on coding using the French classification for procedures [Classification Commune des Actes Médicaux (CCAM)] and International Classification of Diseases (ICD-10)...
April 17, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29607624/burden-and-consequences-of-retained-cardiovascular-implantable-electronic-device-lead-fragments-after-heart-transplantation
#13
Paulino A Alvarez, Brett W Sperry, Antonio L Perez, Kenneth Varian, Timothy Raymond, Michael Tong, Ayman A Hussein, David O Taylor
We performed a retrospective review of 402 consecutive patients who underwent heart transplantation at our institution between January 2009 and March 2017. A retained cardiovascular implantable electronic device (CIED) fragment was identified after transplantation in 49 of the 301 patients (16.2%) with CIED at baseline. Patients with retained fragments had leads with longer dwell times (median 2596 [1982, 3389] vs 1384 [610, 2202] days, P < .001), higher prevalence of previously abandoned leads (14.3% vs 2...
April 1, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29584858/incidence-and-factors-associated-with-infective-endocarditis-in-patients-undergoing-left-sided-heart-valve-replacement
#14
Lauge Østergaard, Nana Valeur, Nikolaj Ihlemann, Morten Holdgaard Smerup, Henning Bundgaard, Gunnar Gislason, Christian Torp-Pedersen, Niels Eske Bruun, Lars Køber, Emil Loldrup Fosbøl
Aims: Patients with left-sided heart valve replacement are considered at high-risk of infective endocarditis (IE). However, data on the incidence and risk factors associated with IE are sparse. Methods and results: Through Danish administrative registries, we identified patients who underwent left-sided heart valve replacement from January 1996 to December 2015. Patients were categorized in mitral and aortic valve replacement (MVR and AVR) and followed until: 12 years after valve surgery, end of study, death, emigration, or hospitalization due to IE, whichever came first...
March 23, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29564522/antibiotic-prophylaxis-practices-in-pediatric-cardiac-implantable-electronic-device-procedures-a-survey-of-the-pediatric-and-congenital-electrophysiology-society-paces
#15
Spenser Y Chen, Scott R Ceresnak, Kara S Motonaga, Anthony Trela, Debra Hanisch, Anne M Dubin
Cardiac implantable electronic device (CIED) infections are associated with significant morbidity in the pediatric device population, with a tenfold higher risk of infection in children compared to adults. The 2010 American Heart Association (AHA) guidelines recommend a single dose of systemic antibiotic (ABX) prophylaxis prior to CIED implantation and no post-operative (OP) ABX. However, there is limited data regarding adherence to this recommendation among the pediatric community. To assess current clinical practices for CIED ABX prophylaxis in pediatrics; whether the AHA guidelines are being followed; and if not, the reasons for non-adherence...
March 22, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29563819/a-case-of-brucella-melitensis-endocarditis-in-a-patient-with-cardiovascular-implantable-electronic-device
#16
Wasl Al-Adsani, Ali Ahmad, Mohammad Al-Mousa
Background: Brucellosis is a bacterial infection, caused by the nonmotile gram-negative aerobic coccobacilli. The clinical manifestation of brucellosis is variable, ranging from mild disease to severe disease. The gold standard test to confirm the diagnosis of brucellosis is assaying blood, bone marrow, or other body fluids or by tissue culture. Preferred first-line treatment in adults with uncomplicated, nonlocalized disease consists of doxycycline-aminoglycoside combination. The recommended duration of treatment is 6 weeks...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29518265/attempted-salvage-of-infected-cardiovascular-implantable-electronic-devices-are-there-clinical-factors-that-predict-success
#17
James E Peacock, Jeanette M Stafford, Katherine Le, Muhammad Rizwan Sohail, Larry M Baddour, Jordan M Prutkin, Stephan B Danik, Holenarasipur R Vikram, Marta Hernandez-Meneses, José M Miró, Elisabeth Blank, Christoph K Naber, Roger G Carrillo, Arnold J Greenspon, Chi-Hong Tseng, Daniel Z Uslan
BACKGROUND: Published guidelines mandate complete device removal in cases of cardiovascular implantable electronic device (CIED) infection. Clinical predictors of successful salvage of infected CIEDs have not been defined. METHODS: Data from the Multicenter Electrophysiologic Device Infection Collaboration, a prospective, observational, multinational cohort study of CIED infection, were used to investigate whether clinical predictors of successful salvage of infected devices could be identified...
March 8, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29508843/application-of-an-infection-control-protocol-icp-reduced-cardiac-device-infection-cdi-in-low-volume-centers
#18
Gongchang Guan, Zhongwei Liu, Yong Zhang, Fangyun Wang, Haiming Ji, Xuewen Li, Yuan Chen, Xiaoqiang Yang, Jianxia Wei, Kai Yu, Ming Zhang
BACKGROUND Cardiac device infection (CDI) is a serious complication of cardiovascular implantable electronic device (CIED) implantations. Many risk factors have been identified, but several are still uncertain. This study aimed to identify and evaluate the risk factors. Moreover, an infection control protocol (ICP) was carried out, and its efficacy in reducing CDIs was investigated. MATERIAL AND METHODS A total of 1259 patients who received permanent pacemaker (PPM) implantations were enrolled in this study in a 3-year period in a high-volume center and low-volume centers in the central area of Shaanxi Province, China...
March 6, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29428137/management-of-device-infections
#19
REVIEW
Khalid Aljabri, Ann Garlitski, Jonathan Weinstock, Christopher Madias
The rate of cardiac implantable electronic device (CIED) infection has increased disproportionately to the rate of implantation. Expanded indications for CIED implantation combined with a sicker patient population contribute to this increased rate. Device-related infections are most commonly due to perioperative contamination, and infection risk increases in conjunction with procedural complexity. Early pocket re-exploration and upgrade procedures confer a higher infectious risk. Confirmed CIED infection requires prompt removal of the CIED system combined with antimicrobial therapy...
March 2018: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/29428134/lead-management-and-lead-extraction
#20
REVIEW
Charles J Love
Management of patients with cardiac implantable electronic devices (CIEDs) has become complex given the complications that can occur with implanted lead systems. Clinical problems such as infection, lead failure, and occluded vessels create situations that demand intervention to remove leads. Due to adhesions that occur in the venous system and at the endomyocardial attachment site, simple traction to remove a lead is often not sufficient. Infection is a mandatory reason to remove the entire CIED system. Tools and techniques are now available that enable a skilled operator to extract leads with a great deal of efficacy and safety...
March 2018: Cardiac Electrophysiology Clinics
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