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https://www.readbyqxmd.com/read/29023475/de-novo-transcriptome-sequencing-of-isaria-cateniannulata-and-comparative-analysis-of-gene-expression-in-response-to-heat-and-cold-stresses
#1
Dingfeng Wang, Liangde Li, Guangyuan Wu, Liette Vasseur, Guang Yang, Pengrong Huang
Isaria cateniannulata is a very important and virulent entomopathogenic fungus that infects many insect pest species. Although I. cateniannulata is commonly exposed to extreme environmental temperature conditions, little is known about its molecular response mechanism to temperature stress. Here, we sequenced and de novo assembled the transcriptome of I. cateniannulata in response to high and low temperature stresses using Illumina RNA-Seq technology. Our assembly encompassed 17,514 unigenes (mean length = 1,197 bp), in which 11,445 unigenes (65...
2017: PloS One
https://www.readbyqxmd.com/read/29016771/predictors-of-long-term-survival-free-from-relapses-after-extraction-of-infected-cied
#2
Igor Diemberger, Mauro Biffi, Stefano Lorenzetti, Cristian Martignani, Elena Raffaelli, Matteo Ziacchi, Claudio Rapezzi, Davide Pacini, Giuseppe Boriani
Aims: We explored the possible predictors of long-term prognosis after transvenous lead extraction (TLE) for a cardiac implantable device related infection (CIEDI), including the modified Duke score result. Methods and results: We performed a single centre prospective observational study in a population of consecutive patients referred for TLE to a teaching hospital to treat a CIEDI without associated valve-endocarditis. 121 patients were enrolled between January 2012 and March 2016...
August 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28928258/implantable-cardiac-defibrillator-infections-the-emerging-importance-of-mycobacterium-fortuitum
#3
Menfil Orellana-Barrios, David A Sotello Aviles, Olusegun Oyenuga, Kenneth Nugent
Infection is a clinically relevant complication associated with intracardiac devices. Atypical mycobacteria, particularly Mycobacterium fortuitum, have been increasingly implicated in cardiovascular implantable electronic device (CIED) infections. We present a case of M. fortuitum CIED infection in a patient with ischaemic cardiomyopathy occurring approximately 3 weeks after insertion. The recognition and adequate treatment, including device removal, tissue sampling and the determination of antimicrobial sensitivities, are essential in the proper management of these patients...
September 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28918305/single-center-experience-with-percutaneous-extraction-of-cardiac-implantable-electric-devices
#4
Ayako Okada, Morio Shoda, Hiroaki Tabata, Wataru Shoin, Hideki Kobayashi, Takahiro Okano, Koji Yoshie, Yasutaka Oguchi, Takahiro Takeuchi, Ken Kato, Koichiro Kuwahara
BACKGROUND: The estimated incidence of infected cardiac implantable electric devices (CIED) has recently increased to 1-2% in Japan. Extraction of long-term implanted devices is generally difficult. There are few reports about lead extraction in Japan. We describe our experience with and outcomes of lead extraction using excimer lasers, mechanical sheaths, and manual extraction. METHODS: We retrospectively analyzed the characteristics, types of devices, and indications for extraction in 29 patients with 67 leads who required CIED lead extraction at Shinshu University Hospital between April 2014 and October 2016...
September 13, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28913626/role-of-18-f-fdg-pet-ct-in-the-diagnosis-of-cardiovascular-implantable-electronic-device-infections-a-meta-analysis
#5
Maryam Mahmood, Ayse Tuba Kendi, Saira Farid, Saira Ajmal, Geoffrey B Johnson, Larry M Baddour, Panithaya Chareonthaitawee, Paul A Friedman, M Rizwan Sohail
OBJECTIVE: We performed a meta-analysis evaluating the use of fluorine-18-fluorodeoxyglucose ((18)F-FDG) positron-emission tomography (PET)/computed tomography (CT) in the diagnosis of cardiovascular implantable electronic device (CIED) infections. BACKGROUND: PET/CT may be helpful in the diagnosis of CIED infection, particularly in patients with the absence of localizing signs or definitive echocardiographic findings. METHODS: PubMed, Embase, Cochrane library, CINAHL, Web of Knowledge, and www...
September 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28846153/international-survey-of-knowledge-attitudes-and-practices-of-cardiologists-regarding-prevention-and-management-of-cardiac-implantable-electronic-device-infections
#6
Daniel C DeSimone, Anwar A Chahal, Christopher V DeSimone, Samuel J Asirvatham, Paul A Friedman, Larry M Baddour, M Rizwan Sohail
BACKGROUND: Cardiovascular implantable electronic devices (CIEDs) can be life-saving. However, complications from CIED infection can be life-threatening often requiring device removal. Despite publication of CIED infection management guidelines there remains marked variation in clinical practice. OBJECTIVE: To better understand and quantify these differences, we conducted a multi-national survey of practitioners of CIED management. METHODS: An electronic survey was sent to Heart Rhythm Society members, spanning 70 countries across six continents...
August 28, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28844107/impacts-of-a-care-process-model-and-inpatient-electrophysiology-service-on-cardiovascular-implantable-electronic-device-infections-a-preliminary-evaluation
#7
Eugene M Tan, Avish Nagpal, Daniel C DeSimone, Brenda Anderson, Jane Linderbaum, Thomas De Ziel, Zhuo Li, Muhammad R Sohail, Yong-Mei Cha, Erica Loomis, Raul Espinosa, Paul A Friedman, Kevin Greason, Henry Schiller, Abinash Virk, Walter R Wilson, James M Steckelberg, Larry M Baddour
PURPOSE: Cardiovascular implantable electronic device infection (CIEDI) rates are rising. To improve outcomes, our institution developed an online care process model (CPM) and a specialized inpatient heart rhythm service (HRS). METHODS: This retrospective review compared hospital length of stay (LOS), mortality, and times to subspecialty consultation and procedures before and after CPM and HRS availability. RESULTS: CPM use was associated with shortened time to surgical consultation (median 2 days post-CPM vs...
August 26, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28830879/outcomes-associated-with-extraction-versus-capping-and-abandoning-pacing-and-defibrillator-leads
#8
Sean D Pokorney, Xiaojuan Mi, Robert K Lewis, Melissa Greiner, Laurence M Epstein, Roger G Carrillo, Emily P Zeitler, Sana M Al-Khatib, Donald D Hegland, Jonathan P Piccini
Background -Lead management is an increasingly important aspect of care in patients with cardiac implantable electronic devices (CIED); however, relatively little is known about long-term outcomes after capping and abandoning leads. Methods -Using the 5% Medicare sample, we identified patients with (1) de novo CIED implants between 1/1/2000 and 12/31/2013 and (2) a subsequent lead addition or extraction ≥12 months after the de novo implant. Patients who underwent extraction for infection were excluded. Using multivariable Cox proportional hazards models, cumulative incidence of all-cause mortality, device-related infection, device revision, and lead extraction at 1 and 5 years were compared for the extract versus the cap and abandon groups...
August 22, 2017: Circulation
https://www.readbyqxmd.com/read/28815459/a-roadmap-for-reducing-cardiac-device-infections-a-review-of-epidemiology-pathogenesis-and-actionable-risk-factors-to-guide-the-development-of-an-infection-prevention-program-for-the-electrophysiology-laboratory
#9
REVIEW
Westyn Branch-Elliman
PURPOSE OF REVIEW: Cardiovascular implantable electronic device (CIED) infections are highly morbid, common, and costly, and rates are increasing (Sohail et al. Arch Intern Med 171(20):1821-8 2011; Voigt et al. J Am Coll Cardiol 48(3):590-1 2006). Factors that contribute to the development of CIED infections include patient factors (comorbid conditions, self-care, microbiome), procedural details (repeat procedure, contamination during procedure, appropriate pre-procedural prep, and antimicrobial use), environmental and organizational factors (patient safety culture, facility barriers, such as lack of space to store essential supplies, quality of environmental cleaning), and microbial factors (type of organism, virulence of organism)...
August 16, 2017: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/28811391/cardiac-implantable-electronic-device-lead-extraction-using-the-lead-locking-device-system-keeping-it-simple-safe-and-inexpensive-with-mechanical-tools-and-local-anesthesia
#10
Antonis S Manolis, Georgios Georgiopoulos, Sofia Metaxa, Spyridon Koulouris, Dimitris Tsiachris
OBJECTIVE: We have previously reported our successful approach for percutaneous cardiac implantable electronic device (CIED) lead extraction using inexpensive tools, which we have continued over the years. Herein we report the results of the systematic use of a unique stylet, the lead-locking device (LLD), which securely locks the entire lead lumen, aided with non-powered telescoping sheaths in 54 patients to extract 98 CIED leads. METHODS: This prospective observational clinical study included 38 men and 16 women aged 68...
August 11, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28769025/delayed-pacemaker-generator-pocket-and-lead-primary-infection-due-to-burkholderia-cepacia
#11
Fatma Ben Abid, Hussam Al-Saoub, Faraj Howadi, Ahmed AlBishawi, Maliha Thapur
BACKGROUND Recently, the use of cardiac implantable electrophysiological devices (CIEDs) has increased. Advances in medical technology, an increasingly aging population, increases in clinical indications, and expanded medical insurance coverage for these devices have all contributed to this trend. Infection is considered to be one of the most serious complications of CIEDs and carries a significant risk of morbidity and mortality. Although infection with Staphylococcus sp. accounts for the majority of cases, other bacteria have been implicated as causative agents of infection of CIEDs...
August 3, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28696088/cardiac-lead-management-the-future-of-transvenous-lead-extraction-approaches-and-technologies
#12
Luca Segreti, Jean-Claude Deharo
INTRODUCTION: The implantation rate of Cardiac implantable Elecrtonical Devices has consistently increased in the last 20 years, so as related complication rates. According, devices infections and malfunctions required the development of appropriate strategies, including lead removal. Transvenous lead extraction (TLE) is the gold standard for lead removal. The increasing rate of CIED implantations and of CIED related complications highlight the importance of transvenous lead extraction (TLE)...
July 10, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28694202/comparative-outcomes-of-cefazolin-versus-nafcillin-for-methicillin-susceptible-staphylococcus-aureus-bacteraemia-a-prospective-multicentre-cohort-study-in-korea
#13
S Lee, K-H Song, S-I Jung, W B Park, S H Lee, Y-S Kim, Y G Kwak, Y K Kim, S M Kiem, H-I Kim, E S Kim, K-H Park, N J Kim, H-C Jang, H B Kim
OBJECTIVES: No randomized controlled trials have evaluated the comparative outcomes of cefazolin versus nafcillin for methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia. METHODS: A prospective observational cohort study including all S. aureus bacteraemia was conducted at 10 hospitals. Patients (≥15 years) with MSSA bacteraemia who received cefazolin or nafcillin as definitive antibiotics were included. The rates of treatment failure (premature discontinuation of antibiotics because of adverse effects, switching of antibiotics because of clinical failure, all-cause mortality within 1 month, or recurrence) were compared between the cefazolin and nafcillin groups...
July 8, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28674615/in-vivo-biocompatibility-and-pacing-function-study-of-silver-ion-based-antimicrobial-surface-technology-applied-to-cardiac-pacemakers
#14
James Shawcross, Ameet Bakhai, Ali Ansaripour, James Armstrong, David Lewis, Philip Agg, Roberta De Godoy, Gordon Blunn
INTRODUCTION: Evidence suggests that the rate of cardiovascular implantable electronic device (CIED) infections is increasing more rapidly than the rates of CIED implantation and is associated with considerable mortality, morbidity and health economic impact. Antimicrobial surface treatments are being developed for CIEDs to reduce the risk of postimplantation infection within the subcutaneous implant pocket. METHODS AND ANALYSIS: The feasibility of processing cardiac pacemakers with the Agluna antimicrobial silver ion surface technology and in vivo biocompatibility were evaluated...
2017: Open Heart
https://www.readbyqxmd.com/read/28634537/a-meta-analysis-of-antibacterial-envelope-use-in-prevention-of-cardiovascular-implantable-electronic-device-infection
#15
Sajid Ali, Yousuf Kanjwal, Steven R Bruhl, Mohammed Alo, Mohammed Taleb, Syed S Ali, Ameer Kabour, Owais Khawaja
OBJECTIVES: Cardiac implantable electronic device (CIED) infection has been a major clinical problem in addition to being a major financial burden. In spite of antimicrobial prophylaxis, CIED infection rates have been increasing disproportionately. We therefore conducted this meta-analysis to assess the role of TYRX antibiotic envelope for the prevention of CIED infection. METHODS: Using extensive online search, we conducted a meta-analysis of studies reporting CIED infections with versus without the use of TYRX antibiotic envelope...
May 2017: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/28605036/still-begging-for-a-solution-the-ongoing-problem-of-device-cied-infection
#16
EDITORIAL
Qi Zheng, John D Fisher
No abstract text is available yet for this article.
June 12, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28603001/low-lateral-thoracic-site-for-cardiac-implantable-electronic-device-implantation-a-viable-alternative-in-patients-with-limited-access-options-after-infected-device-extraction
#17
Jackson J Liang, Robert D Schaller, Danesh S Modi, Andres Enriquez, Gregory E Supple, Joshua M Cooper
BACKGROUND: Device reimplantation after extraction because of cardiac implantable electronic device (CIED) infection in pacemaker-dependent patients can be challenging in individuals with limited access options. OBJECTIVE: The purpose of this study was to describe a straightforward, low lateral thoracic implantation technique for patients with a patent axillary vein but unavailable bilateral pectoral sites. METHODS: Nine pacemaker-dependent patients (mean age 70 ± 13 years, 7 male) who underwent CIED extraction and low lateral thoracic reimplantation in whom bilateral pectoral sites were unavailable were included in the study...
October 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28602063/risk-factors-for-poor-prognosis-in-nosocomial-infective-endocarditis
#18
Ji-Won Hwang, Seung Woo Park, Eun Jeong Cho, Ga Yeon Lee, Eun Kyoung Kim, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Jae-Hoon Song
Background/Aims: The aim of our study was to compare the characteristics of nosocomial infective endocarditis (NIE) with community-acquired infective endocarditis (CIE) and to determine independent risk factors for in-hospital death. Methods: We retrospectively reviewed the medical records of 560 patients diagnosed with infective endocarditis. NIE was defined by a diagnosis made > 72 hours after hospital admission or within 2 months of hospital discharge. Results: Among the 560 cases reviewed, 121 were classified as NIE...
June 2, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28594654/rationale-study-design-and-pilot-phase-of-the-management-of-antithrombotic-therapy-in-patients-undergoing-electrophysiological-device-surgery-italian-national-multicenter-observational-registry
#19
Valerio Zacà, Marco Breschi, Alberto Mandorli, Luca Panchetti, Giuseppe Ricciardi, Stefano Viani, Pasquale Notarstefano
AIMS: To investigate the different strategies adopted for the management of antithrombotic therapy and the related hemorrhagic and infective complication rates in patients undergoing cardiac implantable electronic devices (CIEDs) surgery in a real-world setting. METHODS: THE Management of AntiThrOMbotic therApy in patients undergoing electrophysiological device surgery: Italian NatiOnal Multicenter Observational REgistry (HEMATOMA NO MORE) is an observational, prospective, multicenter, national cohort study (with a retrospective, multicenter, regional pilot phase) designed to enroll patients with standard indications to CIED implantations/replacements receiving concomitant antithrombotic therapy...
June 7, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28582500/comparison-of-epicardial-vs-endocardial-reimplantation-in-pacemaker-dependent-patients-with-device-infection
#20
Tilman Perrin, Baptiste Maille, Coralie Lemoine, Noémie Resseguier, Frédéric Franceschi, Linda Koutbi, Jérôme Hourdain, Jean-Claude Deharo
Aims: Reimplantation of cardiac implantable electronic devices (CIEDs) after extraction due to device infection is a major issue in pacemaker-dependent patients. We compared in-hospital and long-term outcomes with two techniques: epicardial reimplantation (EPI) before CIED extraction and temporary pacing (TP) with a view to delayed endocardial reimplantation. Methods and results: Two cohorts of consecutive pacemaker-dependent patients who underwent transvenous lead extraction at our tertiary centre were included in this retrospective cohort study...
June 3, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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