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https://www.readbyqxmd.com/read/28329125/outcomes-in-patients-with-cardiovascular-implantable-electronic-device-infection-managed-with-chronic-antibiotic-suppression
#1
Eugene M Tan, Daniel C DeSimone, M Rizwan Sohail, Larry M Baddour, Walter R Wilson, James M Steckelberg, Abinash Virk
Background: Most cardiovascular implantable electronic device (CIED) recipients are elderly, have multiple comorbid conditions, and are at increased risk of CIED infection (CIEDI). Current guidelines recommend complete device removal in patients with CIEDI to prevent relapse and mortality. However, comorbidities or other factors may preclude device removal, thus prompting a non-surgical approach that includes chronic antibiotic suppression (CAS). There are limited data on outcomes of patients receiving CAS for CIEDI...
February 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28321212/microbiological-characteristics-and-clinical-features-of-cardiac-implantable-electronic-device-infections-at-a-tertiary-hospital-in-china
#2
Ruobing Wang, Xuebin Li, Qi Wang, Yawei Zhang, Hui Wang
The incidence of cardiac implantable electronic device (CIED) infections is rapidly increasing worldwide. However, the microbiological characteristics and clinical features of symptomatic CIED infections are not well described. The present study included patients with CIED infections in China, and their pocket tissues were collected for clinical microbiological determination. A total of 219 patients with CIED infections were investigated; of these patients, 145 (66.2%) were positive for CIED infection in pocket tissue cultures and 24 (11...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28315744/cardiac-implantable-electronic-device-infections-who-is-at-greatest-risk
#3
Parijat Saurav Joy, Gagan Kumar, Jeanne E Poole, Barry London, Brian Olshansky
BACKGROUND: Cardiac Implantable Electronic Device (CIED) infections are associated with hospitalization, mortality, increased costs and adverse outcomes. OBJECTIVE: Determine the burden of infections for CIEDs based on device type, associated comorbidities and clinical characteristics over a 12-year period. METHODS: Utilizing the National Inpatient Sample database from 2000-2012, procedures for device related infection (DRI) were identified using ICD-9-CM code for CIED removal with diagnosis codes for device-related infection or systemic infection...
March 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28264059/biomarker-based-diagnosis-of-pacemaker-and-implantable-cardioverter-defibrillator-pocket-infections-a-prospective-multicentre-case-control-evaluation
#4
Carsten Lennerz, Hrvoje Vrazic, Bernhard Haller, Siegmund Braun, Tobias Petzold, Ilka Ott, Agnes Lennerz, Jonathan Michel, Patrick Blažek, Isabel Deisenhofer, Peter Whittaker, Christof Kolb
BACKGROUND: The use of cardiac implantable electronic devices (CIED) has risen steadily, yet the rate of cardiac device infections (CDI) has disproportionately increased. Amongst all cardiac device infections, the pocket infection is the most challenging diagnosis. Therefore, we aimed to improve diagnosis of such pocket infection by identifying relevant biomarkers. METHODS: We enrolled 25 consecutive patients with invasively and microbiologically confirmed pocket infection...
2017: PloS One
https://www.readbyqxmd.com/read/28240419/enhanced-antimicrobial-effects-of-decellularized-extracellular-matrix-cormatrix-with-added-vancomycin-and-gentamicin-for-device-implant-protection
#5
Thomas F Deering, Carlos Chang, Carl Snyder, Selvamuthu K Natarajan, Robert Matheny
BACKGROUND: The incidence of cardiac implantable electronic device (CIED) infections has risen significantly over the past years. Although several devices are currently available to decrease the incidence of infection, most are made from non-viable synthetic material and are more prone to infection than vascularized tissue. OBJECTIVE: This study was undertaken to assess the resistance to infection of the CorMatrix CanGaroo, a CIED envelope made of decellularised extracellular matrix (ECM) hydrated in different antibiotic solutions...
February 27, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28194345/transaxillary-subpectoral-placement-of-cardiac-implantable-electronic-devices-in-young-female-patients
#6
Joo Hyun Oh, Chae Min Kim, Seung Yong Song, Jae Sun Uhm, Dae Hyun Lew, Dong Won Lee
BACKGROUND: The current indications of cardiac implantable electronic devices (CIEDs) have expanded to include young patients with serious cardiac risk factors, but CIED placement has the disadvantage of involving unsightly scarring and bulging of the chest wall. A collaborative team of cardiologists and plastic surgeons developed a technique for the subpectoral placement of CIEDs in young female patients via a transaxillary approach. METHODS: From July 2012 to December 2015, subpectoral CIED placement via an axillary incision was performed in 10 young female patients, with a mean age of 25...
January 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28131641/retrospective-comparative-analysis-of-cardiovascular-implantable-electronic-device-infections-with-and-without-the-use-of-antibacterial-envelopes
#7
COMPARATIVE STUDY
A Hassoun, E D Thottacherry, M Raja, M Scully, A Azarbal
BACKGROUND: Cardiovascular implantable electronic device (CIED) infections are associated with morbidity and mortality. Peri-operative systemic intravenous antibiotic prophylaxis reduces the rate of CIED infections. AIGISRx, a polymer envelope implanted with the CIED, releases minocycline and rifampin, and has been introduced to reduce infections. METHODS: Retrospective review of 184 patients who underwent CIED implantation was conducted. Ninety-two patients were implanted with an AIGISRx envelope (AIGISRx group) and 92 patients were not implanted with an AIGISRx envelope (control group)...
March 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28111362/incidence-of-bleeding-related-complications-during-primary-implantation-and-replacement-of-cardiac-implantable-electronic-devices
#8
Christine I Nichols, Joshua G Vose
BACKGROUND: Use of cardiac implantable electronic devices (CIEDs) is increasing. The incidence of bleeding-related complications during CIED procedures and the association with subsequent infection risk have been studied in trial settings but not in nonrandomized "real-world" populations. METHODS AND RESULTS: This retrospective database analysis of US insurance claims from the Truven MarketScan database (2009-2013) evaluated the incidence of bleeding complications during, or in the 30 days following, a CIED procedure and the association between bleeding and subsequent infection in days 31 to 365 of follow-up...
January 22, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28073883/infective-endocarditis-and-risk-of-death-after-cardiac-implantable-electronic-device-implantation-a-nationwide-cohort-study
#9
Cengiz Özcan, Jakob Raunsø, Morten Lamberts, Lars Køber, Tommi Bo Lindhardt, Niels Eske Bruun, Marie Louise Laursen, Christian Torp-Pedersen, Gunnar Hilmar Gislason, Morten Lock Hansen
AIMS: To determine the incidence, risk factors, and mortality of infective endocarditis (IE) following implantation of a first-time, permanent, cardiac implantable electronic device (CIED). METHODS AND RESULTS: From Danish nationwide administrative registers (beginning in 1996), we identified all de-novo permanent pacemakers (PMs) and implantable cardioverter defibrillators (ICDs) together with the occurrence of post-implantation IE-events in the period from 2000-2012...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27996097/prevention-of-cardiac-implantable-electronic-device-infections-single-operator-technique-with-use-of-povidone-iodine-double-gloving-meticulous-aseptic-antiseptic-measures-and-antibiotic-prophylaxis
#10
Antonis S Manolis, Helen Melita
BACKGROUND: Cardiac implantable electronic device (CIED) implantation is complicated by infection still at a worrisome rate of 2-5%. Since early on during device implantation procedures, we have adopted an infection-preventive technique which has hitherto resulted in effective prevention of infections. Herein we present our results of applying this technique by a single operator in a prospective series of 762 consecutive patients undergoing device implantation. METHODS: A meticulous search for and treatment of active, occult, or smoldering infection was undertaken preoperatively...
January 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27941400/lead-extraction-considerations-for-the-referring-cardiologist
#11
Ayman Hussein, Bruce L Wilkoff
The population of patients with cardiac implantable electronic devices (CIED) continues to grow owing to increasing indications in an aging population and breakthroughs in both the medical and surgical care of patients with heart disease. In clinical practice there has been a growing need for device and lead extraction due to the growing population of patients with CIEDs and the subsequent need for system upgrades or revisions because of complications, infections and lead advisory alerts. In this condensed review, we will discuss aspects of transvenous lead extraction, with a special focus on considerations that would be relevant to the referring cardiologist...
November 17, 2016: Cardiology in Review
https://www.readbyqxmd.com/read/27850287/648-utility-of-procalcitonin-for-viral-lower-respiratory-tract-infections-in-the-pediatric-icu
#12
John Kotula, Wayne Moore, Arun Chopra, Jeffrey Cies
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27830083/the-seroprevalence-of-human-cystic-echinococcosis-in-iran-a-systematic-review-and-meta-analysis-study
#13
REVIEW
Reza Shafiei, Saeed Hosseini Teshnizi, Kurosh Kalantar, Maryam Gholami, Golnush Mirzaee, Fatemeh Mirzaee
Human cystic echinococcosis (HCE), a zoonotic infection of the larval stage of Echinococcus granulosus, has high effect on public health in human population all around the world. Iran is one of the most important endemic areas in the Middle East. This systematic review and meta-analysis was performed to evaluate the seroprevalence of HCE in Iranian population. An electronic search for articles from 1985 until April 2015 was performed using data bases PubMed, Scopus, Google Scholar, Magiran, IranMedex, Iran Doc, and Scientific Information Database (SID) both in English and in Persian...
2016: Journal of Parasitology Research
https://www.readbyqxmd.com/read/27721936/role-of-radionuclide-imaging-for-diagnosis-of-device-and-prosthetic-valve-infections
#14
REVIEW
Jean-François Sarrazin, François Philippon, Mikaël Trottier, Michel Tessier
Cardiovascular implantable electronic device (CIED) infection and prosthetic valve endocarditis (PVE) remain a diagnostic challenge. Cardiac imaging plays an important role in the diagnosis and management of patients with CIED infection or PVE. Over the past few years, cardiac radionuclide imaging has gained a key role in the diagnosis of these patients, and in assessing the need for surgery, mainly in the most difficult cases. Both (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) and radiolabelled white blood cell single-photon emission computed tomography/computed tomography (WBC SPECT/CT) have been studied in these situations...
September 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/27714592/characteristics-of-cefazolin-inoculum-effect-positive-methicillin-susceptible-staphylococcus-aureus-infection-in-a-multicentre-bacteraemia-cohort
#15
MULTICENTER STUDY
K-H Song, S-I Jung, S Lee, S Park, S M Kiem, S H Lee, Y G Kwak, Y K Kim, H-C Jang, Y-S Kim, H-I Kim, C J Kim, K-H Park, N J Kim, M-D Oh, H B Kim
Cefazolin treatment failure has been observed in high-inoculum infections caused by methicillin-susceptible Staphylococcus aureus (MSSA) with a cefazolin inoculum effect (CIE). However, data on the characteristics and risk factors for the acquisition of CIE-positive MSSA infection are scarce. CIE positivity was measured as an MIC ≥ 16 μg/ml with a high inoculum (∼5 × 10(7) CFU/ml). The blaZ gene type was assessed through sequence analysis. The clinical characteristics and risk factors for the acquisition of CIE-positive MSSA infection were assessed...
February 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27707785/outcomes-of-lead-extraction-without-subsequent-device-reimplantation
#16
Mohammed A Al-Hijji, Ammar M Killu, Omid Yousefian, David O Hodge, Jae Yoon Park, Shrinivas Hebsur, Abdallah El Sabbagh, Victor G Pretorius, Michael J Ackerman, Paul A Friedman, Ulrika Birgersdotter-Green, Yong-Mei Cha
AIMS: Outcomes among patients who do not receive device reimplantation after cardiovascular implantable electronic device (CIED) extraction have not been well studied. The present study aims to investigate the outcomes of patients without device reimplantation after lead extraction and device removal. METHODS AND RESULTS: We retrospectively searched for consecutive patients who underwent CIED extraction at Mayo Clinic, Rochester, MN and University of California San Diego Medical Center from 2001 through 2012...
October 5, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27659878/worldwide-randomized-antibiotic-envelope-infection-prevention-trial-wrap-it
#17
Khaldoun G Tarakji, Suneet Mittal, Charles Kennergren, Ralph Corey, Jeanne Poole, Kurt Stromberg, Daniel R Lexcen, Bruce L Wilkoff
BACKGROUND: Cardiac implantable electronic device (CIED) infection is a major complication that is associated with significant morbidity and mortality. The aim of this study is to determine whether Medtronic TYRX absorbable envelope reduces the risk of CIED infection through 12 months of follow-up post procedure. METHODS: WRAP-IT is a randomized, prospective, multi center, international, single-blinded study. Up to 7,764 subjects who are undergoing CIED generator replacement, upgrade, or revision, or a de novo CRT-D implant, will be enrolled and randomized (1:1) to receive the TYRX envelope or not...
October 2016: American Heart Journal
https://www.readbyqxmd.com/read/27635069/outcomes-of-transvenous-lead-extraction-for-cardiovascular-implantable-electronic-device-infections-in-patients-with-prosthetic-heart-valves
#18
Xin-Miao Huang, Hai-Xia Fu, Li Zhong, Jiang Cao, Samuel J Asirvatham, Larry M Baddour, M Rizwan Sohail, Vuyisile T Nkomo, Rick A Nishimura, Kevin L Greason, Rakesh M Suri, Paul A Friedman, Yong-Mei Cha
BACKGROUND: Lead-related or valve-related endocarditis can complicate cardiovascular implantable electronic device (CIED) infection in patients with both CIED and prosthetic valves. The objective of this study was to determine the outcomes of transvenous lead extraction for CIED infection in patients with prosthetic valves. METHODS AND RESULTS: We retrospectively screened 794 transvenous lead extraction procedures, between September 1, 2001 and August 31, 2012, at Mayo Clinic to identify patients with prosthetic valves who underwent lead extraction for infection...
September 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/27588155/lead-extractions-in-patients-with-cardiac-implantable-electronic-device-infections-single-center-experience
#19
Masahiko Goya, Michio Nagashima, Ken-Ichi Hiroshima, Kentaro Hayashi, Yu Makihara, Masato Fukunaga, Yoshimori An, Masatsugu Ohe, So-Ichiro Yamazato, Ko-Ichiro Sonoda, Kennosuke Yamashita, Kouji Katayama, Tomoaki Ito, Harushi Niu, Kenji Ando, Hiroyoshi Yokoi, Masashi Iwabuchi
BACKGROUND: Lead extraction using laser sheaths is performed mainly for cardiac implantable electronic device (CIED) infections. However, there are few reports concerning the management of CIED infections in Japan. METHODS AND RESULTS: Lead extraction procedures were performed in 183 patients targeting 450 leads (atrial leads: 170, ventricular: 181, implantable cardioverter-defibrillators (ICDs): 79, and coronary sinus: 20). One hundred twenty patients (65.6%) presented with pocket infections without the presentation of an endovascular infection...
August 2016: Journal of Arrhythmia
https://www.readbyqxmd.com/read/27588154/incidence-of-cardiac-implantable-electronic-device-infections-and-migrations-in-japan-results-from-a-129-institute-survey
#20
Hiroshi Nakajima, Masami Taki
BACKGROUND: We conducted a survey of the infection burden associated with the implantation of cardiac implantable electronic devices (CIEDs) in Japan. METHODS: The institutes were selected using annual device implantation data provided by Medtronic Japan Co., Ltd. The data sampling period was from January 1 to December 31, 2013. Institutes were classified into Group P, at which only pacemakers were implanted, and Group A, at which other CIEDs were implanted. Group P was further classified into three sub-groups by implantation number...
August 2016: Journal of Arrhythmia
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