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https://www.readbyqxmd.com/read/29188432/18f-fdg-pet-ct-now-endorsed-by-guidelines-across-all-types-of-cied-infection-evidence-limited-but-growing
#1
EDITORIAL
Fozia Zahir Ahmed, Parthiban Arumugam
No abstract text is available yet for this article.
November 29, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29171319/cost-effectiveness-of-tyrx%C3%A2-absorbable-antibacterial-envelope-for-prevention-of-cardiovascular-implantable-electronic-device-infection
#2
Gemma Kay, Elizabeth L Eby, Benedict Brown, Julie Lyon, Simon Eggington, Gayathri Kumar, Elisabeth Fenwick, M Rizwan Sohail, David Jay Wright
AIMS: Infection is a major complication of cardiovascular implantable electronic device (CIED) therapy that usually requires device extraction and is associated with increased morbidity and mortality. The TYRX Antibacterial Envelope is a polypropylene mesh that stabilises the CIED and elutes minocycline and rifampin to reduce the risk of post-operative infection. METHODS: A decision tree was developed to assess the cost-effectiveness of TYRX versus standard of care (SOC) following implantation of four CIED device types...
November 24, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29162159/pulsed-electron-avalanche-knife-peak-plasmablade%C3%A2-in-pacemaker-and-defibrillator-procedures
#3
Elif Kaya, Matthias Totzeck, Tienush Rassaf
BACKGROUND: The pulsed electron avalanche knife (PEAK) PlasmaBlade™ is an innovative electrosurgical device that uses a novel technology to cut tissues. It has been proven to be safe and feasible in ear, nose, and throat surgery, but there are only limited data concerning the use of PlasmaBlade™ instead of conventional electrocautery in cardiac implantable electronic device (CIED) procedures except for generator replacements. METHODS: We conducted a retrospective, single-center study with patients undergoing CIED surgery at our center between December 2015 and March 2017 and evaluate the feasibility and the clinical outcome of the PlasmaBlade™...
November 21, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29153041/association-of-procalcitonin-values-and-bacterial-infections-in-pediatric-patients-receiving-extracorporeal-membrane-oxygenation
#4
Vi Ean Tan, Wayne S Moore, Arun Chopra, Jeffrey J Cies
OBJECTIVE: There is increasing data in pediatrics demonstrating procalcitonin (PCT) is more sensitive and specific than other biomarkers in the setting of bacterial infections. However, the use of PCT in neonatal and pediatric extracorporeal membrane oxygenation (ECMO) is not well described. Therefore, the purpose of this study was to describe the clinical utility of PCT in determining the absence or presence of bacterial infections in neonatal and pediatric patients on ECMO. METHODS: This was a retrospective electronic medical record (EMR) review of data between January 1, 2010 to June 30, 2016 at a single, free-standing, children 's hospital...
November 1, 2017: Perfusion
https://www.readbyqxmd.com/read/29112080/%C3%AE-lactam-therapeutic-drug-management-in-the-picu
#5
Jeffrey J Cies, Wayne S Moore, Adela Enache, Arun Chopra
OBJECTIVES: To determine whether contemporary β-lactam anti-infective dosing recommendations in critically ill children achieve concentrations associated with maximal anti-infective activity. The secondary objective was to describe the microbiological and clinical outcomes associated with β-lactam therapeutic drug management. DESIGN: Electronic Medical Record Review. SETTING: A 189-bed, freestanding children's tertiary care teaching hospital in Philadelphia, PA...
November 3, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29110166/effect-of-battery-longevity-on-costs-and-health-outcomes-associated-with-cardiac-implantable-electronic-devices-a-markov-model-based-monte-carlo-simulation
#6
Jordana K Schmier, Edmund C Lau, Jasmine D Patel, Juergen A Klenk, Arnold J Greenspon
INTRODUCTION: The effects of device and patient characteristics on health and economic outcomes in patients with cardiac implantable electronic devices (CIEDs) are unclear. Modeling can estimate costs and outcomes for patients with CIEDs under a variety of scenarios, varying battery longevity, comorbidities, and care settings. The objective of this analysis was to compare changes in patient outcomes and payer costs attributable to increases in battery life of implantable cardiac defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-D)...
November 6, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29032885/the-subtle-connection-between-development-of-cardiac-implantable-electrical-device-infection-and-survival-after-complete-system-removal-an-observational-prospective-multicenter-study
#7
Igor Diemberger, Federico Migliore, Mauro Biffi, Alberto Cipriani, Emanuele Bertaglia, Stefano Lorenzetti, Giulia Massaro, Gaia Tanzarella, Giuseppe Boriani
BACKGROUND: Despite the improvements in transvenous lead extraction (TLE), patients with cardiac implantable device related infection (CIEDI) have a poor prognosis at long term. We explored the possible role of factors associated with development of CIEDI as predictors of post-TLE survival. METHODS: We performed a multi-center prospective observational study in a population of consecutive patients referred for TLE for CIEDI. We adopted a previously developed 10-point scale for CIEDI risk stratification and assessed its performance in predicting post-TLE survival...
October 9, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29023475/de-novo-transcriptome-sequencing-of-isaria-cateniannulata-and-comparative-analysis-of-gene-expression-in-response-to-heat-and-cold-stresses
#8
Dingfeng Wang, Liangde Li, Guangyuan Wu, Liette Vasseur, Guang Yang, Pengrong Huang
Isaria cateniannulata is a very important and virulent entomopathogenic fungus that infects many insect pest species. Although I. cateniannulata is commonly exposed to extreme environmental temperature conditions, little is known about its molecular response mechanism to temperature stress. Here, we sequenced and de novo assembled the transcriptome of I. cateniannulata in response to high and low temperature stresses using Illumina RNA-Seq technology. Our assembly encompassed 17,514 unigenes (mean length = 1,197 bp), in which 11,445 unigenes (65...
2017: PloS One
https://www.readbyqxmd.com/read/29016771/predictors-of-long-term-survival-free-from-relapses-after-extraction-of-infected-cied
#9
Igor Diemberger, Mauro Biffi, Stefano Lorenzetti, Cristian Martignani, Elena Raffaelli, Matteo Ziacchi, Claudio Rapezzi, Davide Pacini, Giuseppe Boriani
Aims: We explored the possible predictors of long-term prognosis after transvenous lead extraction (TLE) for a cardiac implantable device related infection (CIEDI), including the modified Duke score result. Methods and results: We performed a single centre prospective observational study in a population of consecutive patients referred for TLE to a teaching hospital to treat a CIEDI without associated valve-endocarditis. 121 patients were enrolled between January 2012 and March 2016...
August 9, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28928258/implantable-cardiac-defibrillator-infections-the-emerging-importance-of-mycobacterium-fortuitum
#10
Menfil Orellana-Barrios, David A Sotello Aviles, Olusegun Oyenuga, Kenneth Nugent
Infection is a clinically relevant complication associated with intracardiac devices. Atypical mycobacteria, particularly Mycobacterium fortuitum, have been increasingly implicated in cardiovascular implantable electronic device (CIED) infections. We present a case of M. fortuitum CIED infection in a patient with ischaemic cardiomyopathy occurring approximately 3 weeks after insertion. The recognition and adequate treatment, including device removal, tissue sampling and the determination of antimicrobial sensitivities, are essential in the proper management of these patients...
September 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28918305/single-center-experience-with-percutaneous-extraction-of-cardiac-implantable-electric-devices
#11
Ayako Okada, Morio Shoda, Hiroaki Tabata, Wataru Shoin, Hideki Kobayashi, Takahiro Okano, Koji Yoshie, Yasutaka Oguchi, Takahiro Takeuchi, Ken Kato, Koichiro Kuwahara
BACKGROUND: The estimated incidence of infected cardiac implantable electric devices (CIED) has recently increased to 1-2% in Japan. Extraction of long-term implanted devices is generally difficult. There are few reports about lead extraction in Japan. We describe our experience with and outcomes of lead extraction using excimer lasers, mechanical sheaths, and manual extraction. METHODS: We retrospectively analyzed the characteristics, types of devices, and indications for extraction in 29 patients with 67 leads who required CIED lead extraction at Shinshu University Hospital between April 2014 and October 2016...
September 13, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28913626/role-of-18-f-fdg-pet-ct-in-the-diagnosis-of-cardiovascular-implantable-electronic-device-infections-a-meta-analysis
#12
Maryam Mahmood, Ayse Tuba Kendi, Saira Farid, Saira Ajmal, Geoffrey B Johnson, Larry M Baddour, Panithaya Chareonthaitawee, Paul A Friedman, M Rizwan Sohail
OBJECTIVE: We performed a meta-analysis evaluating the use of fluorine-18-fluorodeoxyglucose ((18)F-FDG) positron-emission tomography (PET)/computed tomography (CT) in the diagnosis of cardiovascular implantable electronic device (CIED) infections. BACKGROUND: PET/CT may be helpful in the diagnosis of CIED infection, particularly in patients with the absence of localizing signs or definitive echocardiographic findings. METHODS: PubMed, Embase, Cochrane library, CINAHL, Web of Knowledge, and www...
September 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28846153/international-survey-of-knowledge-attitudes-and-practices-of-cardiologists-regarding-prevention-and-management-of-cardiac-implantable-electronic-device-infections
#13
Daniel C DeSimone, Anwar A Chahal, Christopher V DeSimone, Samuel J Asirvatham, Paul A Friedman, Larry M Baddour, M Rizwan Sohail
BACKGROUND: Cardiovascular implantable electronic devices (CIEDs) can be life-saving. However, complications from CIED infection can be life-threatening, often requiring device removal. Despite publication of CIED infection management guidelines, there remains marked variation in clinical practice. OBJECTIVE: To better understand and quantify these differences, we conducted a multinational survey of practitioners of CIED management. METHODS: An electronic survey was sent to Heart Rhythm Society members, spanning 70 countries across six continents...
August 28, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28844107/impacts-of-a-care-process-model-and-inpatient-electrophysiology-service-on-cardiovascular-implantable-electronic-device-infections-a-preliminary-evaluation
#14
Eugene M Tan, Avish Nagpal, Daniel C DeSimone, Brenda Anderson, Jane Linderbaum, Thomas De Ziel, Zhuo Li, Muhammad R Sohail, Yong-Mei Cha, Erica Loomis, Raul Espinosa, Paul A Friedman, Kevin Greason, Henry Schiller, Abinash Virk, Walter R Wilson, James M Steckelberg, Larry M Baddour
PURPOSE: Cardiovascular implantable electronic device infection (CIEDI) rates are rising. To improve outcomes, our institution developed an online care process model (CPM) and a specialized inpatient heart rhythm service (HRS). METHODS: This retrospective review compared hospital length of stay (LOS), mortality, and times to subspecialty consultation and procedures before and after CPM and HRS availability. RESULTS: CPM use was associated with shortened time to surgical consultation (median 2 days post-CPM vs...
October 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28830879/outcomes-associated-with-extraction-versus-capping-and-abandoning-pacing-and-defibrillator-leads
#15
COMPARATIVE STUDY
Sean D Pokorney, Xiaojuan Mi, Robert K Lewis, Melissa Greiner, Laurence M Epstein, Roger G Carrillo, Emily P Zeitler, Sana M Al-Khatib, Donald D Hegland, Jonathan P Piccini
BACKGROUND: Lead management is an increasingly important aspect of care in patients with cardiac implantable electronic devices; however, relatively little is known about long-term outcomes after capping and abandoning leads. METHODS: Using the 5% Medicare sample, we identified patients with de novo cardiac implantable electronic device implantations between January 1, 2000, and December 31, 2013, and with a subsequent lead addition or extraction ≥12 months after the de novo implantation...
October 10, 2017: Circulation
https://www.readbyqxmd.com/read/28815459/a-roadmap-for-reducing-cardiac-device-infections-a-review-of-epidemiology-pathogenesis-and-actionable-risk-factors-to-guide-the-development-of-an-infection-prevention-program-for-the-electrophysiology-laboratory
#16
REVIEW
Westyn Branch-Elliman
PURPOSE OF REVIEW: Cardiovascular implantable electronic device (CIED) infections are highly morbid, common, and costly, and rates are increasing (Sohail et al. Arch Intern Med 171(20):1821-8 2011; Voigt et al. J Am Coll Cardiol 48(3):590-1 2006). Factors that contribute to the development of CIED infections include patient factors (comorbid conditions, self-care, microbiome), procedural details (repeat procedure, contamination during procedure, appropriate pre-procedural prep, and antimicrobial use), environmental and organizational factors (patient safety culture, facility barriers, such as lack of space to store essential supplies, quality of environmental cleaning), and microbial factors (type of organism, virulence of organism)...
August 16, 2017: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/28811391/cardiac-implantable-electronic-device-lead-extraction-using-the-lead-locking-device-system-keeping-it-simple-safe-and-inexpensive-with-mechanical-tools-and-local-anesthesia
#17
Antonis S Manolis, Georgios Georgiopoulos, Sofia Metaxa, Spyridon Koulouris, Dimitris Tsiachris
OBJECTIVE: We have previously reported our successful approach for percutaneous cardiac implantable electronic device (CIED) lead extraction using inexpensive tools, which we have continued over the years. Herein we report the results of the systematic use of a unique stylet, the lead-locking device (LLD), which securely locks the entire lead lumen, aided with non-powered telescoping sheaths in 54 patients to extract 98 CIED leads. METHODS: This prospective observational clinical study included 38 men and 16 women aged 68...
October 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28769025/delayed-pacemaker-generator-pocket-and-lead-primary-infection-due-to-burkholderia-cepacia
#18
Fatma Ben Abid, Hussam Al-Saoub, Faraj Howadi, Ahmed AlBishawi, Maliha Thapur
BACKGROUND Recently, the use of cardiac implantable electrophysiological devices (CIEDs) has increased. Advances in medical technology, an increasingly aging population, increases in clinical indications, and expanded medical insurance coverage for these devices have all contributed to this trend. Infection is considered to be one of the most serious complications of CIEDs and carries a significant risk of morbidity and mortality. Although infection with Staphylococcus sp. accounts for the majority of cases, other bacteria have been implicated as causative agents of infection of CIEDs...
August 3, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28696088/cardiac-lead-management-the-future-of-transvenous-lead-extraction-approaches-and-technologies
#19
Luca Segreti, Jean-Claude Deharo
INTRODUCTION: The implantation rate of Cardiac implantable Elecrtonical Devices has consistently increased in the last 20 years, so as related complication rates. According, devices infections and malfunctions required the development of appropriate strategies, including lead removal. Transvenous lead extraction (TLE) is the gold standard for lead removal. The increasing rate of CIED implantations and of CIED related complications highlight the importance of transvenous lead extraction (TLE)...
July 10, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28694202/comparative-outcomes-of-cefazolin-versus-nafcillin-for-methicillin-susceptible-staphylococcus-aureus-bacteraemia-a-prospective-multicentre-cohort-study-in-korea
#20
S Lee, K-H Song, S-I Jung, W B Park, S H Lee, Y-S Kim, Y G Kwak, Y K Kim, S M Kiem, H-I Kim, E S Kim, K-H Park, N J Kim, H-C Jang, H B Kim
OBJECTIVES: No randomized controlled trials have evaluated the comparative outcomes of cefazolin versus nafcillin for methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia. METHODS: A prospective observational cohort study including all S. aureus bacteraemia was conducted at 10 hospitals. Patients (≥15 years) with MSSA bacteraemia who received cefazolin or nafcillin as definitive antibiotics were included. The rates of treatment failure (premature discontinuation of antibiotics because of adverse effects, switching of antibiotics because of clinical failure, all-cause mortality within 1 month, or recurrence) were compared between the cefazolin and nafcillin groups...
July 8, 2017: Clinical Microbiology and Infection
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