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https://www.readbyqxmd.com/read/24161451/interaction-between-genetic-variants-and-exposure-to-hurricane-katrina-on-post-traumatic-stress-and-post-traumatic-growth-a-prospective-analysis-of-low-income-adults
#1
Erin C Dunn, Nadia Solovieff, Sarah R Lowe, Patience J Gallagher, Jonathan Chaponis, Jonathan Rosand, Karestan C Koenen, Mary C Waters, Jean E Rhodes, Jordan W Smoller
BACKGROUND: There is considerable variation in psychological reactions to natural disasters, with responses ranging from relatively mild and transitory symptoms to severe and persistent posttraumatic stress (PTS). Some survivors also report post-traumatic growth (PTG), or positive psychological changes due to the experience and processing of the disaster and its aftermath. Gene-environment interaction (GxE) studies could offer new insight into the factors underlying variability in post-disaster psychological responses...
January 2014: Journal of Affective Disorders
https://www.readbyqxmd.com/read/24143106/evidence-for-single-nucleotide-polymorphisms-and-their-association-with-bipolar-disorder
#2
REVIEW
Aleksandra Szczepankiewicz
Bipolar disorder (BD) is a complex disorder with a number of susceptibility genes and environmental risk factors involved in its pathogenesis. In recent years, huge progress has been made in molecular techniques for genetic studies, which have enabled identification of numerous genomic regions and genetic variants implicated in BD across populations. Despite the abundance of genetic findings, the results have often been inconsistent and not replicated for many candidate genes/single nucleotide polymorphisms (SNPs)...
2013: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/19358880/the-genetics-of-bipolar-disorder
#3
REVIEW
J H Barnett, J W Smoller
Bipolar disorder is a mood disorder characterized by impairing episodes of mania and depression. Twin studies have established that bipolar disorder is among the most heritable of medical disorders and efforts to identify specific susceptibility genes have intensified over the past two decades. The search for genes influencing bipolar disorder has been complicated by a paucity of animal models, limited understanding of pathogenesis, and the genetic and phenotypic complexity of the syndrome. Linkage studies have implicated several chromosomal regions as harboring relevant genes, but results have been inconsistent...
November 24, 2009: Neuroscience
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