Valeria Mercadante, Arwa Al Hamad, James McCaul, Christopher Nutting, Kevin Harrington, Dawn Carnell, Teresa Guerrero Urbano, Nicholas Kalavrezos, Julie A Barber, Stephen R Porter, Stefano Fedele
PURPOSE: Radiation therapy-induced xerostomia significantly affects quality of life in head and neck cancer survivors. Neuro-electrostimulation of the salivary glands may safely increase natural salivation and reduce dry mouth symptoms. METHODS AND MATERIALS: This multicenter, double-masked, randomized, sham-controlled clinical trial assessed the long-term effects of a commercially available intraoral neuro-electrostimulating device in lessening xerostomia symptoms, increasing salivary flow, and improving quality of life in individuals with radiation therapy-induced xerostomia...
January 1, 2024: International Journal of Radiation Oncology, Biology, Physics