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https://www.readbyqxmd.com/read/29028650/fast-digestive-proteins-and-sarcopenia-of-aging
#1
Yves Boirie, Christelle Guillet
PURPOSE OF REVIEW: The speed of dietary protein digestion influences postprandial amino acid availability which is crucial for improving altered anabolic response of skeletal muscle one feature of sarcopenia during aging. RECENT FINDINGS: By analogy with carbohydrate and in reference to their absorption rate, dietary proteins can be classified as 'fast' or 'slow' proteins depending on matrix food structure and technological processes, which can influence amino acids availability and their subsequent metabolic actions...
October 11, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29028515/post-biopsy-mri-changes-in-the-size-and-enhancement-of-intramuscular-myxomas-a-report-of-two-cases
#2
Wilbur Wang, Edward Smitaman, Wesley Rubenstein, Tudor Hughes, Brady K Huang
Intramuscular myxomas are benign soft-tissue tumors, characterized by bland spindle-shaped cells and fibroblasts within an abundant mucoid matrix on histologic examination. Classically, these are slowly enlarging masses which may occasionally cause pain, paresthesia, and muscle weakness secondary to mass effect. We present an interesting phenomenon of two histologically confirmed cases of intramuscular myxomas that exhibited size and enhancement changes on follow-up imaging after image-guided biopsy. To our knowledge, this is the first report to describe size and enhancement changes of intramuscular myxomas after biopsy...
September 28, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29028268/relationship-between-the-mediterranean-dietary-pattern-and-musculoskeletal-health-in-children-adolescents-and-adults-systematic-review-and-evidence-map
#3
Jean V Craig, Diane K Bunn, Richard P Hayhoe, Will O Appleyard, Elizabeth A Lenaghan, Ailsa A Welch
An understanding of the modifiable effects of diet on bone and skeletal muscle mass and strength over the life course will help inform strategies to reduce age-related fracture risk. The Mediterranean diet is rich in nutrients that may be important for optimal musculoskeletal health. The aim of this systematic review was to investigate the relationship between a Mediterranean diet and musculoskeletal outcomes (fracture, bone density, osteoporosis, sarcopenia) in any age group. Ten electronic databases were searched...
October 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29027398/nutritional-status-cachexia-and-anorexia-in-women-with-peritoneal-metastasis-and-intraperitoneal-chemotherapy-a-longitudinal-analysis
#4
Ziad Hilal, Günther A Rezniczek, Robert Klenke, Askin Dogan, Clemens B Tempfer
OBJECTIVE: To describe the nutritional status of women with peritoneal metastasis (PM) from recurrent ovarian, fallopian, or peritoneal cancer and to assess longitudinal variations of the cachexia-anorexia syndrome (CAS) during palliative pressurized intraperitoneal aerosol chemotherapy (PIPAC). METHODS: Nutritional assessment included body mass index (BMI), bioelectrical impedance analysis (BIA), and blood chemistry. CAS presence/absence was recorded before and during repeated cycles (1-11) of PIPAC...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29026517/dermatofibrosarcoma-protuberans-coexisting-in-a-patient-with-a-vascular-malformation-a-rare-coincidence
#5
Parthena Deskoulidi, Michael Sofopoulos, Pantelis Diamantopoulos, Thaleia Nikolaidou, Nikolaos Maltzaris, Maria Theodorakopoulou, Christos Klonaris, Niki Arnogiannaki, Maria Kotrotsiou, Spiros Stavrianos
Dermatofibrosarcoma protuberans with fibrosarcomatous differentiation (DFSP-FS) is a rare soft tissue tumor with more aggressive behavior and it is not clear what causes this type of skin cancer. We describe the case of a 48-year-old woman who was born with a vascular malformation in the sternal region and presented suddenly with a soft tissue sarcoma (DFSP-FS) in the same territory. She was initially treated by embolization as the sarcoma was misdiagnosed but the tumor within 6 months seemed to be growing rapidly and reached a giant dimension with ulceration and required surgical intervention...
October 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29026505/indicator-for-success-of-obesity-reduction-programs-in-adolescents-body-composition-or-body-mass-index-evaluating-a-school-based-health-promotion-project-after-12-weeks-of-intervention
#6
Naser Kalantari, Nastaran Keshavarz Mohammadi, Shahram Rafieifar, Hassan Eini-Zinab, Atefeh Aminifard, Hanieh Malmir, Narjes Ashoori, Sheyda Abdi, Maryam Gholamalizadeh, Saeid Doaei
BACKGROUND: Obesity in adolescence is the strongest risk factor for obesity in adulthood. This study aimed to evaluate the effects of a comprehensive lifestyle intervention on different anthropometric indices in 12-16-year-old boy adolescents after 12 Weeks of Intervention. METHODS: A total of 96 male adolescents from two schools participated in this study. The schools were randomly assigned to intervention (53 students) and control school (43 students). Height and weight of students were measured and their body mass index (BMI) was calculated...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29026428/evaluation-of-the-physiological-activity-of-venom-from-the-eurasian-water-shrew-neomys-fodiens
#7
Krzysztof Kowalski, Paweł Marciniak, Grzegorz Rosiński, Leszek Rychlik
BACKGROUND: Animal toxins can have medical and therapeutic applications. Principally, toxins produced by insects, arachnids, snakes and frogs have been characterized. Venomous mammals are rare, and their venoms have not been comprehensively investigated. Among shrews, only the venom of Blarina brevicauda has been analysed so far, and blarina toxin has been proven to be its main toxic component. It is assumed that Neomys fodiens employs its venom to hunt larger prey. However, the toxic profile, properties and mode of action of its venom are largely unknown...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/29026370/preliminary-molecular-characterization-of-a-proinflammatory-and-nociceptive-molecule-from-the-echinometra-lucunter-spines-extracts
#8
Juliana Mozer Sciani, Bianca Zychar, Luis Roberto Gonçalves, Renata Giorgi, Thiago Nogueira, Daniel Carvalho Pimenta
BACKGROUND: Sea urchins are animals commonly found on the Brazilian shoreline, being Echinometra lucunter the most abundant species. Accidents caused by E. lucunter have been reported as one of the most frequent in Brazil, and are characterized by intense pain and inflammation, consequence of spine puncture in the skin. In order to characterize such toxic effects, we isolated one molecule that caused inflammatory and nociceptive effects. METHODS: E. lucunter specimens were collected without gender distinction...
2017: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/29026362/inflammatory-myofibroblastic-tumor-of-the-breast-mimicking-malignancy-in-an-elderly-male
#9
Fouzia Siraj, Manveen Kaur, Varsha Dalal, Jain Sonam
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a rare, distinctive lesion composed of a proliferation of myofibroblastic spindle cells accompanied by an inflammatory infiltrate. It was first described in the lung, but its occurrence at various extrapulmonary sites has also been reported. The literature mentions only a handful of cases of IMT in the breast and only 1 case in the male breast. We report the second case of IMT in the male breast. CASE REPORT: A 60-year-old male presented with a large, lobulated lump in the left breast that had progressively increased in size during the past year...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29026190/growth-hormone-secretagogues-hexarelin-and-jmv2894-protect-skeletal-muscle-from-mitochondrial-damages-in-a-rat-model-of-cisplatin-induced-cachexia
#10
Giuseppe Sirago, Elena Conte, Flavio Fracasso, Antonella Cormio, Jean-Alain Fehrentz, Jean Martinez, Clara Musicco, Giulia Maria Camerino, Adriano Fonzino, Laura Rizzi, Antonio Torsello, Angela Maria Serena Lezza, Antonella Liantonio, Palmiro Cantatore, Vito Pesce
Chemotherapy can cause cachexia, which consists of weight loss associated with muscle atrophy. The exact mechanisms underlying this skeletal muscle toxicity are largely unknown and co-therapies to attenuate chemotherapy-induced side effects are lacking. By using a rat model of cisplatin-induced cachexia, we here characterized the mitochondrial homeostasis in tibialis anterior cachectic muscle and evaluated the potential beneficial effects of the growth hormone secretagogues (GHS) hexarelin and JMV2894 in this setting...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29025708/intermuscular-adipose-tissue-and-subclinical-coronary-artery-calcification-in-midlife-the-cardia-study-coronary-artery-risk-development-in-young-adults
#11
James G Terry, Christina M Shay, Pamela J Schreiner, David R Jacobs, Otto A Sanchez, Jared P Reis, David C Goff, Samuel S Gidding, Lyn M Steffen, John Jeffrey Carr
OBJECTIVE: Excess deposition of fat within and around vital organs and nonadipose tissues is hypothesized to contribute to cardiovascular disease (CVD) risk. We evaluated the association of abdominal intermuscular adipose tissue (IMAT) volume with coronary artery calcification in CARDIA study (Coronary Artery Risk Development in Young Adults) participants. APPROACH AND RESULTS: We measured IMAT in the abdominal muscles, visceral adipose tissue and pericardial adipose tissue, and coronary artery calcification using computed tomography in 3051 CARDIA participants (56% women) at the CARDIA year 25 examination (2010-2011)...
October 12, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29025706/no-augments-endothelial-reactivity-by-reducing-myoendothelial-calcium-signal-spreading-a-novel-role-for-cx37-connexin-37-and-shp-2
#12
Kristin Pogoda, Hanna Mannell, Stephanie Blodow, Holger Schneider, Kai Michael Schubert, Jiehua Qiu, Andreas Schmidt, Axel Imhof, Heike Beck, Laurentia Irina Tanase, Alexander Pfeifer, Ulrich Pohl, Petra Kameritsch
OBJECTIVE: Because of its strategic position between endothelial and smooth muscle cells in microvessels, Cx37 (Connexin 37) plays an important role in myoendothelial gap junctional intercellular communication. We have shown before that NO inhibits gap junctional intercellular communication through gap junctions containing Cx37. However, the underlying mechanism is not yet identified. APPROACH AND RESULTS: Using channel-forming Cx37 mutants exhibiting partial deletions or amino acid exchanges in their C-terminal loops, we now show that the phosphorylation state of a tyrosine residue at position 332 (Y332) in the C terminus of Cx37 controls the gap junction-dependent spread of calcium signals...
October 12, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29024824/body-mass-index-and-fitness-in-high-functioning-children-and-adolescents-with-cerebral-palsy-what-happened-over-a-decade
#13
Maremka Zwinkels, Tim Takken, Thijs Ruyten, Anne Visser-Meily, Olaf Verschuren
BACKGROUND: In recent decades, improving fitness has become an important goal in rehabilitation medicine in children and adolescents with cerebral palsy (CP). AIMS: To compare body mass index (BMI), performance-related fitness, and cardiorespiratory fitness of children with CP measured in 2014 with a comparable sample from 2004. METHODS AND PROCEDURES: In total, 25 high-functioning children with CP (i.e., GMFCS I-II) measured in 2004 (13 boys; mean age 13...
October 9, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29024598/effects-of-long-term-exposures-to-low-iron-and-branched-chain-amino-acid-containing-diets-on-aging-skeletal-muscle-of-fisher-344-brown-norway-rats
#14
Yuho Kim, Sok Sambo Men, Chen Liang, Candace N Receno, Tom D Brutsaert, Donna L Korol, Kevin S Heffernan, Keith C DeRuisseau
Aging skeletal muscle displays an altered iron status that may promote oxidative stress and sarcopenia. A low iron (LI) containing diet could reduce muscle iron status and attenuate age-related muscle atrophy. Supplemental branched-chain amino acids (BCAA) may also alleviate sarcopenia by promoting muscle protein synthesis and iron status improvement. This study examined individual and combined effects of LI and BCAA diets on anabolic signaling and iron status in skeletal muscle of aging rats. Twenty-nine-month-old male F344BN rats consumed the following control-base diets: Control + regular iron (35 mg iron/kg) (CR; n = 11); Control + LI (~6 mg iron/kg) (CL; n = 11); 2×BCAA + regular iron (BR; n = 10); and 2×BCAA + LI (BL; n = 12) for 12 weeks...
October 12, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29024550/biology-of-obesity-and-weight-regain-implications-for-clinical-practice
#15
Mary Madeline Rogge, Bibha Gautam
BACKGROUND AND PURPOSE: Weight loss is recommended as first-line therapy for many chronic illnesses, including obesity. Most patients who do successfully lose weight are unable to maintain their reduced weight. Recent research findings are reviewed and synthesized to explain the biology of obesity, adaptation to weight loss, and weight regain. FINDINGS: Weight regain is a common consequence of successful weight loss. Current obesity management strategies fail to take into consideration the underlying genetic and environmental causes of obesity...
October 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29024435/efect-of-longitudinally-oriented-collagen-conduit-combined-with-nerve-growth-factor-on-nerve-regeneration-after-dog-sciatic-nerve-injury
#16
Yao Yao, Yi Cui, Yannan Zhao, Zhifeng Xiao, Xing Li, Sufang Han, Bing Chen, Yongxiang Fang, Piao Wang, Juli Pan, Jianwu Dai
The research on artificial nerve conduits has become a focus of study in peripheral nerve reconstruction so as a possible replacement for the treatment of autologous nerve grafts in clinics. In this study, we used longitudinally oriented collagen conduit (LOCC) combined with nerve growth factor (NGF) to reconstruct long distance of sciatic nerve defects (35 mm) in adult dog model. The long term follow-up evaluation demonstrated that the LOCC/NGF conduit allowed functional and morphological nerve regeneration at the transection site of the injured sciatic nerve...
October 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29024332/effect-of-resistance-training-set-volume-on-upper-body-muscle-hypertrophy-are-more-sets-really-better-than-less
#17
REVIEW
Cauê V La Scala Teixeira, Yuri Motoyama, Paulo Henrique Silva Marques de Azevedo, Alexandre Lopes Evangelista, James Steele, Danilo Sales Bocalini
BACKGROUND: Resistance training (RT) for upper body muscle hypertrophy (UBMH) typically entails high volumes of sets per muscle group per training session. The majority of RT regimens does not discriminate between upper and lower body muscle groups, while these groups may respond differently to RT set volumes in terms of maximum skeletal muscle mass gain. Recent studies have examined the effect of different set volumes on the extent of UBMH to formulate optimal RT regimens and to make RT programmes more time-efficient...
October 11, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29024128/foetal-development-of-skeletal-muscle-in-bovines-as-a-function-of-maternal-nutrition-foetal-sex-and-gestational-age
#18
T R S Gionbelli, C M Veloso, P P Rotta, S C Valadares Filho, B C Carvalho, M I Marcondes, C S Cunha, M A S Novaes, L D Prezotto, M S Duarte, M P Gionbelli
To determine the effects of maternal nutrition on modifications of foetal development of the skeletal muscle and possible increase in the potential of skeletal muscle growth in cattle, gestating cows were either fed 190% NRC recommendations (overnourished; ON) or 100% NRC recommendation (control; CO). Interaction between maternal nutrition (MN) and the foetal sex (FS) was also investigated. Foetuses were necropsied at four different time points throughout gestation (139, 199, 241 and 268 days of gestation) to assess the mRNA expression of myogenic, adipogenic and fibrogenic markers in skeletal muscle...
October 10, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29023331/effects-of-plyometric-training-on-components-of-physical-fitness-in-prepuberal-male-soccer-athletes-the-role-of-surface-instability
#19
Yassine Negra, Helmi Chaabene, Senda Sammoud, Raja Bouguezzi, Bessem Mkaouer, Younés Hachana, Urs Granacher
Negra, Y, Chaabene, H, Sammoud, S, Bouguezzi, R, Mkaouer, B, Hachana, Y, and Granacher, U. Effects of plyometric training on components of physical fitness in prepuberal male soccer athletes: the role of surface instability. J Strength Cond Res XX(X): 000-000, 2017-Previous studies contrasted the effects of plyometric training (PT) conducted on stable vs. unstable surfaces on components of physical fitness in child and adolescent soccer players. Depending on the training modality (stable vs. unstable), specific performance improvements were found for jump (stable PT) and balance performances (unstable PT)...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29023300/thyroglossal-duct-cyst-at-the-base-of-tongue-the-emerging-role-of-transoral-endoscopic-assisted-surgery
#20
Mario Turri-Zanoni, Paolo Battaglia, Paolo Castelnuovo
Cystic lesions involving the tongue base are rare, generally presenting in pediatric patients, and they may encompass different pathologies such as ranula, lingual ectopic thyroid, thyroglossal duct cyst (TDC), dysontogenetic cysts, benign, and malignant tumors.This paper describes the case of a 19-year-old girl with phonation impairment and mild dysphagia due to limited tongue protrusion and movements. Radiologic examinations revealed a bulky cystic lesion at the base of tongue with displacement of extrinsic lingual muscles...
October 11, 2017: Journal of Craniofacial Surgery
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