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Epinephrine autoinjector

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https://www.readbyqxmd.com/read/29660429/summary-and-simulation-of-reported-adverse-events-from-epinephrine-autoinjectors-and-a-review-of-the-literature
#1
Marcus Shaker, Dana Toy, Christopher Lindholm, Jeffrey Low, Erin Reigh, Matthew Greenhawt
No abstract text is available yet for this article.
April 13, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29615480/improving-anaphylaxis-care-the-impact-of-a-clinical-pathway
#2
Juhee Lee, Bonnie Rodio, Jane Lavelle, Megan Ott Lewis, Rachel English, Sarah Hadley, Jennifer Molnar, Cynthia Jacobstein, Antonella Cianferoni, Jonathan Spergel, Lisa Zielinski, Nicholas Tsarouhas, Terri Brown-Whitehorn
BACKGROUND: Recommended durations of observation after anaphylaxis have been widely variable, with many ranging from 4 to 24 hours. Prolonged durations often prompt admission for ongoing observation. METHODS: In a multidisciplinary quality improvement initiative, we revised our emergency department (ED) anaphylaxis clinical pathway. Our primary aim was to safely decrease the recommended length of observation from 8 to 4 hours and thereby decrease unnecessary hospitalizations...
April 3, 2018: Pediatrics
https://www.readbyqxmd.com/read/29606638/epinephrine-in-severe-allergic-reactions-the-european-anaphylaxis-register
#3
Linus B Grabenhenrich, Sabine Dölle, Franziska Ruëff, Jean-Marie Renaudin, Kathrin Scherer, Claudia Pföhler, Regina Treudler, Alice Koehli, Vera Mahler, Thomas Spindler, Lars Lange, Maria Beatrice Bilò, Nikolaos G Papadopoulos, Jonathan O B Hourihane, Roland Lang, Montserrat Fernández-Rivas, George Christoff, Ewa Cichocka-Jarosz, Margitta Worm
BACKGROUND: Current guidelines recommend intramuscular administration of epinephrine as the first-line drug for the emergency treatment of severe allergic reactions (anaphylaxis), but no randomized trial evidence supports this consensus. OBJECTIVE: We aimed to assess anaphylaxis treatment practices over 10 years, covering several European regions, all allergen sources, and all age groups. METHODS: The European Anaphylaxis Register tracks elicitors, symptoms, emergency treatment, diagnostic workups, and long-term counseling for anaphylaxis incidents through web-based data entry from tertiary allergy specialists, covering information from the emergency respondent, patient, tertiary referral, and laboratory/clinical test results...
March 29, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29561357/how-to-manage-food-allergy-in-nursery-or-school
#4
Roxanne C Oriel, Julie Wang
PURPOSE OF REVIEW: The aim of this review is to describe effective management strategies in nursery or school based upon research findings. RECENT FINDINGS: The prevalence of food allergy and number of emergency department visits for food-related anaphylaxis are increasing in children and adolescents. As there is currently no cure, the most effective strategy to decrease allergic reactions is food allergen avoidance. However, allergic reactions are inevitable in both food allergic children as well as in first-time reactors...
June 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29542268/the-effect-of-oral-immunotherapy-treatment-in-severe-ige-mediated-milk-peanut-and-egg-allergy-in-adults
#5
Jarkko Mäntylä, Tuuli Thomander, Auli Hakulinen, Kaarina Kukkonen, Kati Palosuo, Helena Voutilainen, Anna Pelkonen, Paula Kauppi
INTRODUCTION: The standard care of severe food allergy in both adults and children means avoidance of allergens. In recent years promising results of oral immunotherapy (OIT) have been reported in children. In adults, information on OIT in severe food allergy is very limited. OBJECTIVE: We aimed to study if OIT is possible in adults. METHODS: We report OIT results in 10 adult patients with milk OIT, nine adult patients with peanut OIT, and four adult patients with egg OIT...
June 2018: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/29540279/one-child-s-food-fight-a-case-study-of-oral-immunotherapy-treatment-for-food-allergies
#6
Jessica L Peck, E Katherine Larson, Stacy K Silvers
The prevalence of food allergy has risen dramatically in the last two decades. Primary care providers encounter food-allergic children on a daily basis. Although the standard of care has traditionally been strict avoidance of the allergen and advisement to carry an epinephrine autoinjector in case of an accidental exposure resulting in a severe reaction, food allergy research has progressed in the past decade concerning various immunotherapies that may provide an alternate treatment strategy. Oral immunotherapy (OIT), performed under the supervision of an allergist, is the most widely studied of these therapies...
March 12, 2018: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/29499370/epinephrine-auto-injector-needle-lengths-can-both-subcutaneous-and-periosteal-intraosseous-injection-be-avoided
#7
Sten Dreborg, Laura Kim, Gina Tsai, Harold Kim
BACKGROUND: Epinephrine should be administered intramuscularly in the anterolateral aspect of the thigh. The length of the epinephrine auto-injector (EAI) needle should ensure intramuscular injection. OBJECTIVE: To discuss suitable EAI needle lengths based on ultrasound measurements related to weight. METHODS: The skin-to-muscle distance (STMD) and skin-to-bone distance (STBD) were measured by ultrasound in the mid-third of the anterolateral area of the right thigh when applying high pressure (8 lb; high-pressure EAI [HPEAI]) or low pressure (low-pressure EAI [LPEAI]) on the ultrasound probe...
February 27, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29499368/human-factors-study-in-untrained-adolescents-comparing-a-recently-approved-single-dose-epinephrine-prefilled-syringe-with-an-approved-autoinjector
#8
Ronald B Moss, Karen Daniels, Thomas Moll, Dennis J Carlo
No abstract text is available yet for this article.
May 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29499333/a-survey-of-caregiver-perspectives-on-emergency-epinephrine-autoinjector-sharing
#9
Marcus Shaker, Tsuzumi Kanaoka, Robert G P Murray, Dana Toy, Susan Shaker, Aurora Drew
No abstract text is available yet for this article.
March 1, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29415679/downstream-consequences-of-diagnostic-error-in-pediatric-anaphylaxis
#10
H Thomson, R Seith, S Craig
BACKGROUND: Pediatric anaphylaxis is commonly misdiagnosed in the Emergency Department (ED). We aimed to determine the impact of inaccurate diagnosis on the management and follow-up of pediatric anaphylaxis presenting to the ED. METHODS: Retrospective chart review of ED management of children aged 0-18 years with allergic presentations to three EDs in Melbourne, Australia in 2014. Cases were included if an ED diagnosis of anaphylaxis was recorded, or the presentation met international consensus criteria for anaphylaxis...
February 7, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29351501/pediatric-anaphylaxis-in-the-prehospital-setting-incidence-characteristics-and-management
#11
Emily Andrew, Ziad Nehme, Stephen Bernard, Karen Smith
OBJECTIVE: Although hospital presentations for pediatric anaphylaxis have been described in the literature, a minimal amount is known regarding the incidence, characteristics, and management of pediatric anaphylaxis presenting to emergency medical services (EMS). METHODS: We performed a retrospective observational study of pediatrics (≤16 years) presenting to EMS in Victoria, Australia. Patients with suspected anaphylaxis were included if they were treated with epinephrine before or after EMS arrival...
January 19, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29333893/syringe-administration-of-epinephrine-by-emergency-medical-technicians-for-anaphylaxis
#12
Andrew J Latimer, Sofia Husain, Jonathan Nolan, Vinod Doreswamy, Thomas D Rea, Michael R Sayre, Mickey S Eisenberg
OBJECTIVE: In recent years, the costs of epinephrine autoinjectors (EAIs) in the United States have risen substantially. King County Emergency Medical Services implemented the "Check and Inject" program to replace EAIs by teaching emergency medical technicians (EMTs) to manually aspirate epinephrine from a single-use 1 mg/mL epinephrine vial using a needle and syringe followed by prehospital intramuscular administration of the correct adult or pediatric dose of epinephrine for anaphylaxis or serious allergic reaction...
January 15, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29305517/allergy-teaching-is-suboptimal-and-heterogeneous-in-the-undergraduate-medical-curriculum-in-the-uk
#13
Emily Frances Reid, Mamidipudi Thirumala Krishna, Claire Bethune
AIM: To record the level of allergy teaching occurring in UK medical schools. The UK has experienced an 'allergy epidemic' during the last 3-4 decades. Previous government reviews have emphasised the importance of allergy education and training, treating common allergies in primary care with referral pathways to a specialist and the creation of regional networks. It is acknowledged that the delivery of allergy teaching in UK medical schools is variable, despite the well-recognised need...
January 5, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29236793/diagnosis-and-treatment-of-anaphylaxis-there-is-an-urgent-needs-to-implement-the-use-of-guidelines
#14
Maria Luiza Kraft Köhler Ribeiro, Herberto José Chong Neto, Nelson Augusto Rosario Filho
Anaphylaxis is a severe, life-threatening generalized or systemic hypersensitivity reaction that requires rapid and adequate care. This study aimed to obtain an integrated view of the level of physicians' knowledge related with treatment of anaphylaxis in studies published within the last 5 years. Sixteen studies were found and four points were identified as of the great interest to the authors: (1) emergency pharmacological treatment, (2) epinephrine auto-injectors prescription, (3) knowledge of the main signs of anaphylaxis, and (4) admission of the patient to verify biphasic reactions...
October 2017: Einstein
https://www.readbyqxmd.com/read/29234208/epinephrine-for-anaphylaxis-autoinjector-or-1-mg-vial-or-ampoule
#15
Matthew Grissinger
Epinephrine for anaphylaxis: Autoinjector or 1-mg vial or ampoule?
December 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29229045/accidental-thumb-injection-with-an-epinephrine-autoinjector
#16
Tobias Fritz, Tim Pohlemann, Moritz Klein
No abstract text is available yet for this article.
November 24, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29187266/guidance-for-compassionate-restraint-of-small-children-to-prevent-injuries-with-epinephrine-autoinjectors
#17
Martha V White
BACKGROUND: Without securing a child properly, injuries can happen with the use of pediatric epinephrine autoinjectors (EAI), and lacerations and embedded needles have been reported. Health care providers should ensure that instruction is provided to parents on how to hold a child during an injection with an EAI. OBJECTIVE: To demonstrate the compassionate restraint of small children during an allergic emergency to ensure the safe use of an EAI. METHODS: A patient was used to illustrate a compassionate restraint technique during a mock injection with an EAI...
March 29, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29151840/adherence-with-epinephrine-autoinjector-prescriptions-in-primary-care
#18
Elissa M Abrams, Alexander G Singer, Lisa Lix, Alan Katz, Marina Yogendran, F Estelle R Simons
Background: The aim of this study was to estimate primary adherence for epinephrine autoinjector (EA) prescriptions in primary care practices in Manitoba, Canada. Methods: A retrospective analysis of electronic medical record and administrative data was performed to determine primary adherence, defined as dispensation of a new EA prescription within 90 days of the date the prescription was written. Multivariable logistic regression models were used to test predictors of filling an EA prescription...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/29144278/time-trends-in-food-allergy-diagnoses-epinephrine-orders-and-epinephrine-administrations-in-new-york-city-schools
#19
Elizabeth Feuille, Cheryl Lawrence, Caroline Volel, Scott H Sicherer, Julie Wang
OBJECTIVES: To assess time trends in food allergy diagnoses, epinephrine autoinjector (EAI) prescriptions, and EAI administrations in the school setting. STUDY DESIGN: In this retrospective study, deidentified student data from the New York City Department of Health and Mental Hygiene, which oversees >1 million students in 1800 schools, were provided to investigators. Data from school years 2007-2008 to 2012-2013 pertaining to diagnoses of food allergy, student-specific EAI orders, and EAI administrations among students in New York City were analyzed for trends over time, via the use of ORs and χ2 calculation...
November 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29070274/long-term-omalizumab-use-in-the-treatment-of-exercise-induced-anaphylaxis
#20
Mark R Peterson, Christopher A Coop
Reported is a case of a 39-year-old male who was diagnosed with exercise-induced anaphylaxis (EIA). He was initially treated prophylactically with fexofenadine, montelukast, and ranitidine. He also used an epinephrine autoinjector as needed. He was refractory to these medications and continued to have episodes of EIA. He was then started on a trial of omalizumab, an immunoglobulin E monoclonal antibody, and had resolution of the EIA episodes. After discontinuation of the omalizumab, the EIA episodes returned...
October 1, 2017: Allergy & Rhinology
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