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Epinephrine autoinjector

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https://www.readbyqxmd.com/read/28346591/out-of-pocket-spending-among-commercially-insured-patients-for-epinephrine-autoinjectors-between-2007-and-2014
#1
Kao-Ping Chua, Rena M Conti
No abstract text is available yet for this article.
March 27, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28346577/medicaid-expenditures-and-estimated-rebates-for-epinephrine-autoinjectors-2012-to-2016
#2
Jing Luo, Aaron S Kesselheim, Jerry Avorn
No abstract text is available yet for this article.
March 27, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28339320/basic-life-support-access-to-injectable-epinephrine-across-the-united-states
#3
Ian D Brasted, Michael W Dailey
BACKGROUND:  Aggressive epinephrine administration has growing support in the treatment of anaphylaxis, a life-threatening allergic reaction. Emergency Medical Services (EMS) providers are frequently in a position to provide the first care to someone experiencing an anaphylactic reaction. Intramuscular injection of epinephrine is the definitive pharmacologic treatment for many associated symptoms. While easy to use, epinephrine autoinjectors (EAI) are prohibitively expensive, having increased in price ten-fold in ten years...
March 24, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28284784/trends-in-provider-management-of-patients-with-food-protein-induced-enterocolitis-syndrome
#4
Matthew Greenhawt, J Andrew Bird, Anna H Nowak-Węgrzyn
BACKGROUND: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy. OBJECTIVE: To better understand provider-level variation in FPIES knowledge and management. METHODS: A 23-question online survey was administered to AAAAI members during the spring and summer of 2014. RESULTS: Among 470 respondents, 64% reported "full understanding" of FPIES diagnosis/management; 78.8% reported managing 1 or more patient with FPIES; and 80...
March 8, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28215605/the-high-cost-of-epinephrine-autoinjectors-and-possible-alternatives
#5
Amber N Pepper, Emma Westermann-Clark, Richard F Lockey
Epinephrine autoinjectors provide potentially life-saving therapy for pediatric and adult subjects with systemic allergic reactions, including anaphylaxis. However, the cost of these devices, specifically the EpiPen (Mylan, Canonsburg, Pa), is increasing exponentially. Epinephrine autoinjectors are commonly prescribed in the United States but are not readily available worldwide. Alternatives for the self-administration of epinephrine exist and should be considered for patients who cannot afford or do not have access to these devices...
February 10, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28193793/guidance-on-completing-a-written-allergy-and-anaphylaxis-emergency-plan
#6
Julie Wang, Scott H Sicherer
Anaphylaxis is a potentially life-threatening, severe allergic reaction. The immediate assessment of patients having an allergic reaction and prompt administration of epinephrine, if criteria for anaphylaxis are met, promote optimal outcomes. National and international guidelines for the management of anaphylaxis, including those for management of allergic reactions at school, as well as several clinical reports from the American Academy of Pediatrics, recommend the provision of written emergency action plans to those at risk of anaphylaxis, in addition to the prescription of epinephrine autoinjectors...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28193791/epinephrine-for-first-aid-management-of-anaphylaxis
#7
Scott H Sicherer, F Estelle R Simons
Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinical report from the American Academy of Pediatrics is an update of the 2007 clinical report on this topic. It provides information to help clinicians identify patients at risk of anaphylaxis and new information about epinephrine and epinephrine autoinjectors (EAs). The report also highlights the importance of patient and family education about the recognition and management of anaphylaxis in the community...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28117270/food-allergic-adolescents-at-risk-for-anaphylaxis-a-randomized-controlled-study-of-supervised-injection-to-improve-comfort-with-epinephrine-self-injection
#8
Eyal Shemesh, Christine D'Urso, Christopher Knight, Melissa Rubes, Kinga M Picerno, Ailie M Posillico, Zara Atal, Rachel A Annunziato, Scott H Sicherer
BACKGROUND: Epinephrine self-injection is a key element in the management of food allergy, yet many adolescents report that they may not be able to use the autoinjector when needed. We hypothesized that supervised self-injection with an empty syringe would increase adolescents' comfort with self-injection. OBJECTIVE: The objective of this study was to examine the effect of supervised self-injection on self- and parent-reported comfort and anxiety during and after clinic visits in a food allergy center...
January 20, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28065345/is-the-benefit-from-prescribing-epinephrine-autoinjectors-for-sublingual-immunotherapy-worth-the-cost-lessons-learned-from-clinical-trials
#9
EDITORIAL
Jay Portnoy, Linda S Cox
No abstract text is available yet for this article.
January 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28052801/factors-that-determine-parents-perception-of-their-child-s-risk-of-life-threatening-food-induced-anaphylaxis
#10
Jennifer Ogg, Jayne Wong, Ming Wai Wan, Naomi Davis, Peter D Arkwright
BACKGROUND: Although food allergy is known to be associated with increased disease burden, factors that shape parents' perception of their child's risk of future severe or fatal anaphylaxis are poorly understood. OBJECTIVE: This study aimed to evaluate factors associated with parents' perceived risk of food-induced anaphylaxis. METHODS: A questionnaire-based survey of 202 parents was conducted in a single specialist center outpatient clinic that treats children with food allergies...
January 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27923649/food-allergy-trends-and-epinephrine-autoinjector-presence-in-summer-camps
#11
Natalie R Schellpfeffer, Harvey L Leo, Michael Ambrose, Andrew N Hashikawa
BACKGROUND: Pediatric campers with food allergies are at greater risk for exposure and anaphylaxis. A diagnosis of asthma increases risk for anaphylaxis. Epidemiological investigations of food-allergic children at high risk for allergic reactions requiring intervention in camp settings are lacking. OBJECTIVE: The objectives of this study were to estimate the prevalence of food allergies among otherwise healthy campers in summer camps throughout the United States and Canada, and to assess asthma comorbidity and determine rates of epinephrine autoinjector prescriptions present in this population...
December 3, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27869359/pitfalls-in-the-use-of-epinephrine-for-anaphylaxis-patient-and-provider-opportunities-for-improvement
#12
Michael B Cohen, Stefanie S Saunders, Sarah K Wise, Samih Nassif, Michael P Platt
BACKGROUND: Epinephrine remains the mainstay of treatment for life-threatening allergic reactions. A number of challenges are encountered with epinephrine, resulting in underutilization and misutilization of epinephrine. The purpose of this study was to identify the scope of epinephrine pitfalls and opportunities for improvement in the management of allergy emergencies. METHODS: A PubMed search from 1990 to 2015 was performed to identify all cases and reports pertaining to the use and misuse of epinephrine for anaphylaxis...
March 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27833688/autoinjectors-preferred-for-intramuscular-epinephrine-in-anaphylaxis-and-allergic-reactions
#13
Ronna L Campbell, M Fernanda Bellolio, Megan S Motosue, Kharmene L Sunga, Christine M Lohse, Maria I Rudis
INTRODUCTION: Epinephrine is the treatment of choice for anaphylaxis. We surveyed emergency department (ED) healthcare providers regarding two methods of intramuscular (IM) epinephrine administration (autoinjector and manual injection) for the management of anaphylaxis and allergic reactions and identified provider perceptions and preferred method of medication delivery. METHODS: This observational study adhered to survey reporting guidelines. It was performed through a Web-based survey completed by healthcare providers at an academic ED...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27822074/diagnosis-of-exercise-induced-anaphylaxis-current-insights
#14
REVIEW
Valerio Pravettoni, Cristoforo Incorvaia
Exercise-induced anaphylaxis (EIAn) is defined as the occurrence of anaphylactic symptoms (skin, respiratory, gastrointestinal, and cardiovascular symptoms) after physical activity. In about a third of cases, cofactors, such as food intake, temperature (warm or cold), and drugs (especially nonsteroidal anti-inflammatory drugs) can be identified. When the associated cofactor is food ingestion, the correct diagnosis is food-dependent EIAn (FDEIAn). The literature describes numerous reports of FDEIAn after intake of very different foods, from vegetables and nuts to meats and seafood...
2016: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/27815065/current-evidence-on-safety-and-practical-considerations-for-administration-of-sublingual-allergen-immunotherapy-slit-in-the-united-states
#15
Tolly G Epstein, Christopher Calabria, Linda S Cox, Sten Dreborg
Liquid sublingual allergen immunotherapy (SLIT) has been used off-label for decades, and Food and Drug Administration (FDA)-approved grass and ragweed SLIT tablets have been available in the United States since 2014. Potentially life-threatening events from SLIT do occur, although they appear to be very rare, especially for FDA-approved products. Practice guidelines that incorporate safety precautions regarding the use of SLIT in the United States are needed. This clinical commentary attempts to address unresolved issues including controversy regarding the FDA mandate for the prescription of epinephrine autoinjectors for patients on SLIT; how to approach polysensitized patients; optimal timing and duration of SLIT administration; how to address gaps in therapy; whether antihistamines can prevent local reactions, if certain patient populations (such as persistent asthmatics) should not receive SLIT; and when to instruct patients to self-administer epinephrine...
January 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27814249/challenging-historical-dogma-should-you-really-have-epinephrine-autoinjectors-in-your-emergency-kit
#16
Jason H Goodchild, Mark Donaldson
No abstract text is available yet for this article.
November 2016: General Dentistry
https://www.readbyqxmd.com/read/27475776/parent-reported-prevalence-of-food-allergy-in-mexican-schoolchildren-a-population-based-study
#17
N Ontiveros, E E Valdez-Meza, M J Vergara-Jiménez, A Canizalez-Román, A Borzutzky, F Cabrera-Chávez
BACKGROUND: Food allergy (FA) prevalence is well documented in developed countries and appears to be increasing, but remains unknown in most Latin American countries. We aimed to evaluate on a population basis the parent-reported prevalence of FA and its clinical characteristics in Mexican schoolchildren. METHODS: A validated Spanish version of a structured written questionnaire was administered to parents of schoolchildren aged 5-13 years old from Culiacan, Mexico...
November 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27362323/should-patients-with-pollen-fruit-syndrome-be-prescribed-an-automatic-epinephrine-injector
#18
Constance H Katelaris
PURPOSE OF REVIEW: The review outlines recent insights into our understanding of the complex relationships between pollen and plant food sensitization patterns resulting in the pollen fruit syndrome and the possible risk, upon ingestion, of generalized symptoms rather than localized oropharyngeal reactions. Appreciation of this risk will inform management strategies, which include epinephrine prescription. RECENT FINDINGS: In recent times, the ability to examine molecular components of foods and pollen has allowed further delineation of reactivity patterns...
August 2016: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27283056/the-emperor-has-no-symptoms-the-risks-of-a-blanket-approach-to-using-epinephrine-autoinjectors-for-all-allergic-reactions
#19
Paul J Turner, Audrey DunnGalvin, Jonathan O'B Hourihane
Fatal anaphylaxis in humans is rare and unpredictable. We note a trend to provide allergic individuals with care plans that recommend immediate use of epinephrine autoinjectors if allergen ingestion is suspected, even in the absence of any allergic symptoms, without any supporting evidence base. Instructions to use an autoinjector device, irrespective of reaction severity and especially when symptoms are actually absent, are likely to add to parental and patient anxiety. Of greater concern is the possibility of epinephrine being administered "too early" to treat initial, mild symptoms that then progress to severe anaphylaxis...
November 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27283053/epinephrine-autoinjector-prescribing-trends-an-outpatient-population-based-study-in-olmsted-county-minnesota
#20
Sangil Lee, Erik P Hess, Christine Lohse, Dante Lucas S Souza, Ronna L Campbell
BACKGROUND: The prescribing pattern of epinephrine over time is an indicator of the secular trend of anaphylaxis. However, it is not well known in a population level in the United States. OBJECTIVE: To evaluate the trend of prescriptions for epinephrine autoinjectors in Olmsted County, Minn, residents. METHODS: Outpatient prescriptions for epinephrine were identified among residents of Olmsted County, Minn, between January 1, 2004, and December 31, 2010...
November 2016: Journal of Allergy and Clinical Immunology in Practice
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