keyword
https://read.qxmd.com/read/38537124/genetically-identifying-the-thrombo-embolic-in-cteph
#1
JOURNAL ARTICLE
Christina A Eichstaedt
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38537040/ligneous-conjunctivitis-fresh-frozen-plasma-and-heparin-use-intra-and-postoperatively-a-report-of-two-cases
#2
Sabela Costa Guerra Barreto de Almeida, Patrícia Maria Fernandes Marback
Ligneous conjunctivitis is a rare chronic form of recurrent membranous inflammation and plasminogen deficiency. Ocular manifestations may be associated with sites other than mucous membranes, such as the oral cavity, internal ear, respiratory, genitals, and kidney. Treatment is extremely difficult because of the lack of topic plasminogen drops, and a high volume is required for systemic supplementation. This report aimed to present two patients with ligneous conjunctivitis treated with membrane excision, topical fresh-frozen plasma, and heparin intra-, and postoperatively...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537031/anti-biofilm-effectiveness-of-protocols-for-cleaning-complete-dentures-in-hospitalized-patients-a-randomized-controlled-trial
#3
JOURNAL ARTICLE
Anna Clara Gurgel Gomes, Janaina Gomes Maciel, Amanda Aparecida Maia Neves Garcia, Letycia Accioly Simões Coelho, Giulia Murcia Rodrigues, Vinicius Carvalho Porto, Grigorios Polyzois, Marlise Inêz Klein, Simone Soares, Vanessa Migliorini Urban, Karin Hermana Neppelenbroek
BACKGROUND: Denture biofilm acts as a potential reservoir for respiratory pathogens, considerably increasing the risk of lung infections, specifically aspiration pneumonia, mainly 48h after hospital admission. The establishment of a straightforward, affordable, and applicable hygiene protocol in a hospital environment for the effective control of denture biofilm can be particularly useful to prevent respiratory infections or reduce the course of established lung disease. OBJECTIVES: To evaluate the anti-biofilm effectiveness of denture cleaning protocols in hospitalized patients...
2024: Journal of Applied Oral Science: Revista FOB
https://read.qxmd.com/read/38537025/effects-of-an-early-intensive-blood-pressure-lowering-strategy-using-remifentanil-and-dexmedetomidine-in-patients-with-spontaneous-intracerebral-hemorrhage-a-multicenter-prospective-superiority-randomized-controlled-trial
#4
JOURNAL ARTICLE
Rui Dong, Fen Li, Bin Li, Qiming Chen, Xianjian Huang, Jiehua Zhang, Qibing Huang, Zeli Zhang, Yunxing Cao, Mingbiao Yang, Jianwei Li, Zhanfu Li, Cuiyu Li, Guohua Liu, Shu Zhong, Guang Feng, Ming Zhang, Yumei Xiao, Kangyue Lin, Yunlong Shen, Huanzhang Shao, Yuan Shi, Xiangyou Yu, Xiaopeng Li, Lan Yao, Xinyu Du, Ying Xu, Pei Kang, Guoyi Gao, Bin Ouyang, Wenjin Chen, Zhenhua Zeng, Pingyan Chen, Chunbo Chen, Hong Yang
BACKGROUND: Although it has been established that elevated blood pressure and its variability worsen outcomes in spontaneous intracerebral hemorrhage, antihypertensives use during the acute phase still lacks robust evidence. A blood pressure-lowering regimen using remifentanil and dexmedetomidine might be a reasonable therapeutic option given their analgesic and anti-sympathetic effects. The objective of this superiority trial was to validate the efficacy and safety of this blood pressure-lowering strategy that uses remifentanil and dexmedetomidine in patients with acute intracerebral hemorrhage...
March 27, 2024: Anesthesiology
https://read.qxmd.com/read/38536988/randomized-controlled-trials-advantages-and-pitfalls-when-studying-causality
#5
JOURNAL ARTICLE
Diego Caruso, Juliana C Ferreira
No abstract text is available yet for this article.
March 22, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536987/arteriovenous-malformation
#6
JOURNAL ARTICLE
Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti
No abstract text is available yet for this article.
March 22, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536986/role-of-the-pulmonary-function-laboratory-in-investigating-diaphragm-dysfunction
#7
JOURNAL ARTICLE
Leticia Zumpano Cardenas, Pauliane Vieira Santana, André Luís Pereira de Albuquerque
No abstract text is available yet for this article.
March 22, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536985/asthma-remission
#8
EDITORIAL
Paul M O'Byrne
No abstract text is available yet for this article.
March 22, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536984/one-step-forward-in-understanding-sleep-in-hypersensitivity-pneumonitis-patients
#9
EDITORIAL
Paulo Mateus Madureira Soares Mariano, Pedro Rodrigues Genta
No abstract text is available yet for this article.
March 22, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536983/clinical-outcomes-before-and-after-videofluoroscopic-swallow-study-in-children-24-months-of-age-or-younger
#10
JOURNAL ARTICLE
Fabiola Luciane Barth, Deborah Salle Levy, Marisa Gasparin, Cláudia Schweiger, Denise Manica, Camila Dalbosco Gadenz, Paulo José Cauduro Maróstica
OBJECTIVE: To evaluate the combined impact of videofluoroscopic swallow study (VFSS) and therapeutic feeding and swallowing interventions on clinical outcomes in children with oropharyngeal dysphagia (OPD). METHODS: This was an uncontrolled longitudinal analytical study in which OPD patients were evaluated before and after VFSS. Children ≤ 24 months of age diagnosed with OPD in a clinical setting and undergoing VFSS for investigation and management of OPD were included in the study...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536982/lung-cancer-screening-in-brazil-recommendations-from-the-brazilian-society-of-thoracic-surgery-brazilian-thoracic-association-and-brazilian-college-of-radiology-and-diagnostic-imaging
#11
JOURNAL ARTICLE
Luiz Fernando Ferreira Pereira, Ricardo Sales Dos Santos, Daniel Oliveira Bonomi, Juliana Franceschini, Ilka Lopes Santoro, André Miotto, Thiago Lins Fagundes de Sousa, Rodrigo Caruso Chate, Bruno Hochhegger, Artur Gomes Neto, Airton Schneider, César Augusto de Araújo Neto, Dante Luiz Escuissato, Gustavo Faibischew Prado, Luciana Costa-Silva, Mauro Musa Zamboni, Mario Claudio Ghefter, Paulo César Rodrigues Pinto Corrêa, Pedro Paulo Teixeira E Silva Torres, Ricardo Kalaf Mussi, Valdair Francisco Muglia, Irma de Godoy, Wanderley Marques Bernardo
Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536981/relative-incidence-of-interstitial-lung-diseases-in-brazil
#12
JOURNAL ARTICLE
Simone Lobo Krupok Matias, Carlos Alberto de Castro Pereira, Maria Raquel Soares, Flávia Castro Velasco Fernandes, Maria Auxiliadora Carmo Moreira, Fernanda Maciel de Aguiar Baptista, Tarciane Aline Prata, Gediel Cordeiro Junior, Eliane Viana Mancuzo
OBJECTIVE: To assess the relative frequency of incident cases of interstitial lung diseases (ILDs) in Brazil. METHODS: This was a retrospective survey of new cases of ILD in six referral centers between January of 2013 and January of 2020. The diagnosis of ILD followed the criteria suggested by international bodies or was made through multidisciplinary discussion (MDD). The condition was characterized as unclassifiable ILD when there was no specific final diagnosis following MDD or when there was disagreement between clinical, radiological, or histological data...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536980/connective-tissue-disease-associated-interstitial-lung-disease
#13
JOURNAL ARTICLE
Karin Mueller Storrer, Carolina de Souza Müller, Maxwell Cássio de Albuquerque Pessoa, Carlos Alberto de Castro Pereira
Connective tissue disease-associated interstitial lung disease (CTD-ILD) represents a group of systemic autoimmune disorders characterized by immune-mediated organ dysfunction. Systemic sclerosis, rheumatoid arthritis, idiopathic inflammatory myositis, and Sjögren's syndrome are the most common CTDs that present with pulmonary involvement, as well as with interstitial pneumonia with autoimmune features. The frequency of CTD-ILD varies according to the type of CTD, but the overall incidence is 15%, causing an important impact on morbidity and mortality...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536970/diagnosis-and-treatment-of-asthma-in-childhood-an-overview-of-guidelines
#14
JOURNAL ARTICLE
Laissa Harumi Furukawa, Laura de Castro E Garcia, Marina Puerari Pieta, Miguel Ângelo de Castro, Leonardo Araújo Pinto, Paulo M Pitrez
No abstract text is available yet for this article.
March 25, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536913/cardiac-tissue-model-of-immune-induced-dysfunction-reveals-the-role-of-free-mitochondrial-dna-and-the-therapeutic-effects-of-exosomes
#15
JOURNAL ARTICLE
Rick Xing Ze Lu, Naimeh Rafatian, Yimu Zhao, Karl T Wagner, Erika L Beroncal, Bo Li, Carol Lee, Jingan Chen, Eryn Churcher, Daniel Vosoughi, Chuan Liu, Ying Wang, Andrew Baker, Uriel Trahtemberg, Bowen Li, Agostino Pierro, Ana C Andreazza, Claudia C Dos Santos, Milica Radisic
Despite tremendous progress in the development of mature heart-on-a-chip models, human cell-based models of myocardial inflammation are lacking. Here, we bioengineered a vascularized heart-on-a-chip with circulating immune cells to model severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced acute myocarditis. We observed hallmarks of coronavirus disease (COVID-19)-induced myocardial inflammation, as the presence of immune cells augmented the secretion of proinflammatory cytokines, triggered progressive impairment of contractile function, and altered intracellular calcium transients...
March 29, 2024: Science Advances
https://read.qxmd.com/read/38536829/the-effects-of-gases-from-food-waste-on-human-health-a-systematic-review
#16
JOURNAL ARTICLE
Paulina Rudziak, Evans Batung, Isaac Luginaah
Food waste is a routine and increasingly growing global concern that has drawn significant attention from policymakers, climate change activists and health practitioners. Amid the plurality of discourses on food waste-health linkages, however, the health risks from food waste induced emissions have remained under explored. This lack of evidence is partly because of the lack of complete understanding of the effects of food waste emissions from household food waste on human health either directly through physiological mechanisms or indirectly through environmental exposure effects...
2024: PloS One
https://read.qxmd.com/read/38536820/changes-in-sars-cov-2-viral-load-and-titers-over-time-in-sars-cov-2-infected-human-corpses
#17
JOURNAL ARTICLE
Sayaka Nagasawa, Yuichiro Hirata, Sho Miyamoto, Seiya Ozono, Shun Iida, Harutaka Katano, Shigeki Tsuneya, Kei Kira, Susumu Kobayashi, Makoto Nakajima, Hiroyuki Abe, Masako Ikemura, Isao Yamamoto, Kimiko Nakagawa, Kazumi Kubota, Shinji Akitomi, Iwao Hasegawa, Tetsuo Ushiku, Tadaki Suzuki, Hirotaro Iwase, Yohsuke Makino, Hisako Saitoh
High viral titers of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been detected in human corpses long after death. However, little is known about the kinetics of infectious SARS-CoV-2 in corpses. In this case series study, we investigated the postmortem kinetics of infectious SARS-CoV-2 in human corpses by collecting nasopharyngeal swab samples at multiple time points from six SARS-CoV-2-infected patients after their death. SARS-CoV-2 RNA was detected by quantitative reverse transcription-polymerase chain reaction from nasopharyngeal swab samples collected from all six deceased patients...
2024: PloS One
https://read.qxmd.com/read/38536630/influenza-associated-outcomes-and-healthcare-utilization-by-race-and-ethnicity-in-the-usa-a-retrospective-cohort-study-using-the-national-inpatient-sample-database
#18
JOURNAL ARTICLE
Mohamad El Labban, Wigdan Farah, Perla Mansour, Karine Eid, Yewande E Odeyemi
BACKGROUND: The influenza virus continues to be a public health concern every season. We aimed to evaluate influenza-associated outcomes and healthcare utilization by race and ethnicity. METHODS: We conducted a retrospective cohort study using the National Inpatient Sample across 2019 and 2020. Influenza pneumonia was selected as the principal diagnosis. Outcomes included mortality, use of respiratory support ventilation, length of stay, and total hospitalization charge...
March 27, 2024: Journal of Racial and Ethnic Health Disparities
https://read.qxmd.com/read/38536629/association-of-premorbid-glp-1ra-and-sglt-2i-prescription-alone-and-in-combination-with-covid-19-severity
#19
JOURNAL ARTICLE
Klara R Klein, Trine J Abrahamsen, Anna R Kahkoska, G Caleb Alexander, Christopher G Chute, Melissa Haendel, Stephanie S Hong, Hemalkumar Mehta, Richard Moffitt, Til Stürmer, Kajsa Kvist, John B Buse
INTRODUCTION: People with type 2 diabetes are at heightened risk for severe outcomes related to COVID-19 infection, including hospitalization, intensive care unit admission, and mortality. This study was designed to examine the impact of premorbid use of glucagon-like peptide-1 receptor agonist (GLP-1RA) monotherapy, sodium-glucose cotransporter-2 inhibitor (SGLT-2i) monotherapy, and concomitant GLP1-RA/SGLT-2i therapy on the severity of outcomes in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
March 27, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/38536578/the-role-of-macrophages-in-lung-fibrosis-and-the-signaling-pathway
#20
REVIEW
Xingmei Wang, Jiaxu Zhou, Xinrui Li, Chang Liu, Lan Liu, Hong Cui
Lung fibrosis is a dysregulated repair process caused by excessive deposition of extracellular matrix that can severely affect respiratory function. Macrophages are a group of immune cells that have multiple functions and can perform a variety of roles. Lung fibrosis develops with the involvement of pro-inflammatory and pro-fibrotic factors secreted by macrophages. The balance between M1 and M2 macrophages has been proposed to play a role in determining the trend and severity of lung fibrosis. New avenues and concepts for preventing and treating lung fibrosis have emerged in recent years through research on mitochondria, Gab proteins, and exosomes...
March 27, 2024: Cell Biochemistry and Biophysics
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