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https://www.readbyqxmd.com/read/29029106/iatrogenic-cushing-syndrome-in-a-child-with-congenital-adrenal-hyperplasia-erroneous-compounding-of-hydrocortisone
#1
Julia E Barillas, Daniel Eichner, Ryan Van Wagoner, Phyllis W Speiser
Context: Patients with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH) require lifelong treatment with glucocorticoids. In growing children the drug of choice is hydrocortisone. Commercially available hydrocortisone tablets do not conform to very low doses prescribed to infants and toddlers, and compounded hydrocortisone is often dispensed to meet therapeutic needs. However, safety, efficacy and uniformity of compounded products are not tested. We report a case of Cushing syndrome in a child with CAH who was inadvertently receiving excessive hydrocortisone in compounded form...
September 28, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28991311/selenium-fortification-of-infant-formulas-does-selenium-form-matter
#2
REVIEW
Bo Lönnerdal, Eugenia Vargas-Fernández, Mark Whitacre
Selenium is a trace element essential for the health and development of the growing infant. It is a necessary component of proteins and enzymes required for a variety of functions, including antioxidant defense, modulation of the inflammatory response, and production of thyroid hormones. In breast-fed infants, selenium stores depend on the selenium content of the mother's diet. In formula-fed infants, selenium levels are correlated to the residual selenium stores accumulated in utero and the level and type of selenium fortification used in the formula...
October 9, 2017: Food & Function
https://www.readbyqxmd.com/read/28977026/infants-predict-expressers-cooperative-behavior-through-facial-expressions
#3
Toshinori Kaneshige, Etsuko Haryu
This study investigated infants' ability to use facial expressions to predict the expressers' subsequent cooperative behavior. To explore this problem, Experiment 1 tested 10- and 14-month-olds (N = 16, respectively) by using a violation-of-expectation procedure. In the experiment, all infants were first familiarized with two models, one with a happy facial expression and the other with an angry expression. They were also familiarized with an event in which a duck puppet tried to open a box but failed. During the test phase, infants in the helping condition saw two test scenes; one in which the happy model helped the duck open the box, and the other in which the angry model helped the duck...
2017: PloS One
https://www.readbyqxmd.com/read/28976781/pacifier-use-and-early-life-weight-outcomes-in-the-intervention-nurses-start-infants-growing-on-healthy-trajectories-study
#4
Emily E Hohman, Jennifer S Savage, Leann L Birch, Jessica S Beiler, Ian M Paul
BACKGROUND: Although widely used by infants, little is known about the long-term effects of pacifiers. We investigated relationships between pacifier use in infancy and appetite, temperament, feeding, and weight outcomes through age 2 years using data from the Intervention Nurses Start Infants Growing on Healthy Trajectories study. METHODS: Mother-newborn dyads were randomized to a responsive parenting intervention for obesity prevention or a control group. Infants with data on pacifier use (n = 250) were categorized as using a pacifier beyond early infancy (≥4 months of age) or not...
October 4, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28956803/infant-immunization-coverage-in-italy-2000-2016
#5
Carlo Signorelli, Anna Odone, Paola Cella, Stefania Iannazzo, Fortunato D'Ancona, Raniero Guerra
BACKGROUND: In Italy, national-level immunization polices are included in the National Immunization Prevention Plan (PNPV), whose latest edition - 2017-2019 PNPV - was finally approved in February 2017. Coverage rates are a key measure of immunization system performance; it can inform and support national and regional polices' implementation monitoring, as well as measure the impact of interventions aimed at increasing vaccine uptake. METHODS: We collected, analysed and critically interpreted 2000-2016 Italian national infant immunization coverage trends, by different vaccine, target population, and by Region...
July 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28953843/what-are-the-risks-associated-with-different-selective-serotonin-re-uptake-inhibitors-ssris-to-treat-depression-and-anxiety-in-pregnancy-an-evaluation-of-current-evidence
#6
Kate Womersley, Katherine Ripullone, Mark Agius
A literature review was conducted to elucidate the respective reproductive safety profiles of different SSRIs to inform the prescribing practices of doctors treating pregnant women with anxiety and depression. BACKGROUND: Women are most likely to be diagnosed with depression or anxiety between the ages of 25 and 44 years, which are also the years of childbearing potential (Burke et al., 1991). Therefore a substantial number of women face a decision about whether or not to take an antidepressant or anxiolytic during pregnancy...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28953784/predictors-of-postpartum-depression-in-dubai-a-rapidly-growing-multicultural-society-in-the-united-arab-emirates
#7
Salwa M Alhammadi, Lien Abou Hashem, Zainah R Abusbeih, Fatima S Alzaabi, Salama N Alnuaimi, Ala F Jalabi, Satish C Nair, Frederick R Carrick, Mahera Abdulrahman
BACKGROUND: Postpartum depression (PPD) is a significant public health problem adversely affecting mothers, their newborns, and other members of the family. Although PPD is common and potentially dangerous, only a minority of the cases are identified in primary health care settings during routine care, and the majority of depressed mothers in the community lies unrecognized and therefore untreated. SUBJECTS AND METHODS: In this study, a total of 1500 mothers were approached randomly, 808 accepted to participate, and 504 were within the inclusion criteria (women who had a birth of a singleton full-term healthy infant, had an uncomplicated pregnancy, and were within their one week to six months postpartum)...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28944717/an-overview-of-assessment-methodology-for-obesity-related-variables-in-infants-at-risk
#8
Danae Dinkel, Corrine Hanson, Karsten Koehler, Ann Anderson Berry, Anastasia Kyvelidou, Matthew Bice, Jill Wallen, Danstan Bagenda, Laura Jana, Jana Pressler
BACKGROUND: The first 2 years of a child's life are a particularly critical time period for obesity prevention. AIM: An increasing amount of research across the world is aimed at understanding factors that impact early childhood obesity and developing interventions that target these factors effectively. With this growing interest, new and interdisciplinary research teams are developing to meet this research need. Due to rapid growth velocity during this phase of the lifespan, typical assessments used in older populations may not be valid or applicable in infants, and investigators need to be aware of the pros and cons of specific methodological strategies...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28941901/antimicrobial-efficacy-of-phytochemicals-against-bacillus-cereus-in-reconstituted-infant-rice-cereal
#9
Hayriye Cetin-Karaca, Melissa C Newman
The objective of this study was to determine the potential use of Trans-cinnamaldehyde (TC), (-)-Epigallocatechin gallate (EGCG) and [10]-Gingerol (GI) to inhibit the growth of B. cereus in infant rice cereal reconstituted with infant formula. Samples were inoculated with either vegetative cells or spores of B. cereus (ATCC 14579), and they were treated with 500 ppm (mg/L) TC, EGCG and GI. They were stored at 7 °C, 23 °C, or 37 °C for 0, 4, 8 and 24 h to simulate advance preparation, handling and temperature abuse...
February 2018: Food Microbiology
https://www.readbyqxmd.com/read/28937574/committee-opinion-no-722-marijuana-use-during-pregnancy-and-lactation
#10
(no author information available yet)
Cannabis sativa (marijuana) is the illicit drug most commonly used during pregnancy. The self-reported prevalence of marijuana use during pregnancy ranges from 2% to 5% in most studies. A growing number of states are legalizing marijuana for medicinal or recreational purposes, and its use by pregnant women could increase even further as a result. Because of concerns regarding impaired neurodevelopment, as well as maternal and fetal exposure to the adverse effects of smoking, women who are pregnant or contemplating pregnancy should be encouraged to discontinue marijuana use...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937569/committee-opinion-summary-no-722-marijuana-use-during-pregnancy-and-lactation
#11
(no author information available yet)
Cannabis sativa (marijuana) is the illicit drug most commonly used during pregnancy. The self-reported prevalence of marijuana use during pregnancy ranges from 2% to 5% in most studies. A growing number of states are legalizing marijuana for medicinal or recreational purposes, and its use by pregnant women could increase even further as a result. Because of concerns regarding impaired neurodevelopment, as well as maternal and fetal exposure to the adverse effects of smoking, women who are pregnant or contemplating pregnancy should be encouraged to discontinue marijuana use...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28931390/who-s-holding-the-baby-a-prospective-diary-study-of-the-contact-patterns-of-mothers-with-an-infant
#12
Patricia Therese Campbell, Jodie McVernon, Niraj Shrestha, Paula M Nathan, Nicholas Geard
BACKGROUND: Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on contact patterns across many populations, less attention has been paid to the social contacts of young infants. We collected information on the social contacts of primary carers of young infants and investigated their potential for use as a proxy for contacts made by their infant...
September 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28929093/the-elevated-rate-of-cesarean-section-and-its-contribution-to-non-communicable-chronic-diseases-in-latin-america-the-growing-involvement-of-the-microbiota
#13
REVIEW
Fabien Magne, Alexa Puchi Silva, Bielka Carvajal, Martin Gotteland
The current recommendation of the World Health Organization (WHO) regarding cesarean section (C-section) is that this clinical practice should be carried out only under specific conditions, when the health or life of the mother/newborn dyad is threatened, and that its use should not exceed 10-15% of the total deliveries. However, over the last few decades, the frequency of C-section delivery in medium- and high-income countries has rapidly increased worldwide. This review describes the evolution of this procedure in Latin American countries, showing that today more than half of newborns in the region are delivered by C-section...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28928622/central-perforation-of-atretic-pulmonary-valve-using-coronary-microcatheter
#14
Saurabh Kumar Gupta, Rajnish Juneja, Anita Saxena
Percutaneous perforation of pulmonary valve, using 0.014" guidewires meant for coronary artery chronic total occlusion (CTO), is increasingly being performed for select cases of pulmonary atresia with intact ventricular septum (PA-IVS). Despite growing experience, procedural failures and complications are not uncommon. Even in infants treated successfully, the orifice created in the atretic pulmonary valve is eccentric. In this report, we present usefulness of coronary microcatheter in alignment of perforating coronary guidewire to the center of atretic pulmonary valve resulting in central perforation...
September 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28925669/lower-extremity-abnormalities-in-children
#15
Caitlyn M Rerucha, Caleb Dickison, Drew C Baird
Leg and foot problems in childhood are common causes of parental concern. Rotational problems include intoeing and out-toeing. Intoeing is most common in infants and young children. Intoeing is caused by metatarsus adductus, internal tibial torsion, and femoral anteversion. Out-toeing is less common than intoeing and occurs more often in older children. Out-toeing is caused by external tibial torsion and femoral retroversion. Angular problems include genu varum (bowleg) and genu valgum (knock knee). With pes planus (flatfoot), the arch of the foot is usually flexible rather than rigid...
August 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28925412/prenatal-antimicrobial-use-and-early-childhood-body-mass-index
#16
A E Cassidy-Bushrow, C Burmeister, S Havstad, A M Levin, S V Lynch, D R Ownby, A G Rundle, K J Woodcroft, E M Zoratti, C C Johnson, G Wegienka
BACKGROUND/OBJECTIVES: Growing evidence suggests that antibiotic use is associated with childhood body mass index (BMI), potentially via mechanisms mediated by gut microbiome alterations. Less is known on the potential role of prenatal antimicrobial use in offspring obesity risk. We examined whether prenatal antibiotic or antifungal use was associated with BMI at the age of 2 years in 527 birth cohort participants. METHODS/SUBJECTS: Antimicrobial use was obtained from the prenatal medical record...
August 17, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28925341/physiological-attunement-in-mother-infant-dyads-at-clinical-high-risk-the-influence-of-maternal-depression-and-positive-parenting
#17
Cassandra L Hendrix, Zachary N Stowe, D Jeffrey Newport, Patricia A Brennan
A growing number of research studies have examined the intradyadic coregulation (or attunement) of hypothalamus-pituitary-adrenal axis functioning in mothers and their children. However, it is unclear how early this coregulation may be present in dyads at clinical high risk and whether certain factors, such as maternal depression or positive parenting, are associated with the strength of this coregulation. The present study examined cortisol attunement within mother-infant dyads in a high-risk sample of 233 mothers who received treatment for psychiatric illness during pregnancy and whose infants were 6 months old at the study visit...
September 19, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28924002/variations-in-infant-and-childhood-vitamin-d-supplementation-programs-across-europe-and-factors-influencing-adherence
#18
Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky, Wolfgang Hoegler
BACKGROUND: Nutritional rickets is a growing global public health concern despite existing prevention programs and health policies. We aimed to compare infant and childhood vitamin D supplementation policies, implementation strategies and practices across Europe and explore factors influencing adherence. METHODS: European Society for Paediatric Endocrinology Bone and Growth Plate Working Group members and other specialists completed a questionnaire on country-specific vitamin D supplementation policy and child healthcare programs, socioeconomic factors, policy implementation strategies, and adherence...
September 18, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28905497/alveolar-soft-part-sarcoma-a-case-report-with-emphasis-on-some-unusual-cytological-features
#19
Neelam Sood, Minakshi Gulia
Alveolar soft part sarcoma is a very rare, slow growing highly angiogenic tumor with poor prognosis. Most common site in children and infants is head and neck region and in adults it most commonly occurs in extremities especially thigh. In our case study, an 8 years old female patient presented with a gradually progressive left shoulder lump. FNAC from the lesion showed cellular smears with polyhedral and spindly cells showing abundant finely vacuolated cytoplasm, nuclear pleomorphism, intranuclear pseudoinclusions, and few bare nuclei...
September 14, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28899048/growing-brains-how-adapting-to-africa-advanced-the-treatment-of-infant-hydrocephalus
#20
Benjamin C Warf
No abstract text is available yet for this article.
September 1, 2017: Neurosurgery
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