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https://www.readbyqxmd.com/read/28318856/balloon-aortic-valvuloplasty-in-the-transcatheter-aortic-valve-implantation-era-a-single-center-registry
#1
Ana Rita G Francisco, Miguel Nobre Menezes, Pedro Carrilho Ferreira, Cláudia Jorge, Doroteia Silva, Eduardo Infante de Oliveira, Fausto J Pinto, Pedro Canas da Silva
INTRODUCTION: Percutaneous balloon aortic valvuloplasty (BAV) has been limited by the risk of complications and restenosis. However, growing use of transcatheter aortic valve implantation (TAVI) has revived interest in this technique. We analyzed the current indications for BAV and outcomes in a single center. METHODS: Acute results and long-term outcomes were analyzed in a retrospective single-center registry of patients undergoing BAV between January 2013 and January 2016...
March 16, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28318141/zika-virus-induced-cellular-remodeling
#2
Evan D Rossignol, Kristen N Peters, John H Connor, Esther Bullitt
Zika virus (ZIKV) has been associated with morbidities such as Guillain-Barré, infant microcephaly, and ocular disease. The spread of this positive-sense, single-stranded RNA virus and its growing public health threat underscore gaps in our understanding of basic ZIKV virology. To advance knowledge of the virus replication cycle within mammalian cells, we use serial section three-dimensional electron tomography to demonstrate the widespread remodeling of intracellular membranes upon infection with ZIKV. We report extensive structural rearrangements of the endoplasmic reticulum and reveal stages of the ZIKV viral replication cycle...
March 20, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/28315890/evidence-for-the-effects-of-complementary-feeding-interventions-on-the-growth-of-infants-and-young-children-in-low-and-middle-income-countries
#3
Rebecca A Heidkamp
As momentum for investment in early childhood nutrition grows, so does the evidence base for the effectiveness of interventions to improve complementary feeding in low- and middle-income countries (LMIC), where the risk of early growth faltering is high. The aim of this chapter is to review the current state of the evidence for the impact of two categories of interventions (nutrition education alone and provision of food or nutrient supplements with or without education) on linear and ponderal growth of children aged 6-23 months in LMIC...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28315883/complementary-foods-guidelines-and-practices
#4
Merryn J Netting, Maria Makrides
Complementary feeding, the transition from a breast milk-based diet to inclusion of other sources of nutrition in an infant's diet, is a major milestone in infant development. This transition period is important as it is a time when infants are vulnerable to developing nutritional deficiencies and occurs during a developmental stage when important food-related behavioral patterns are being established. As under- and overnutrition may coexist in children from the same country, it is important that advice provided by complementary feeding guidelines meets the needs of all children helping them to grow and develop into healthy adults...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28306522/infrared-analyzers-for-breast-milk-analysis-fat-levels-can-influence-the-accuracy-of-protein-measurements
#5
Celia Kwan, Gerhard Fusch, Aldin Bahonjic, Niels Rochow, Christoph Fusch
BACKGROUND: Currently, there is a growing interest in lacto-engineering in the neonatal intensive care unit, using infrared milk analyzers to rapidly measure the macronutrient content in breast milk before processing and feeding it to preterm infants. However, there is an overlap in the spectral information of different macronutrients, so they can potentially impact the robustness of the measurement. In this study, we investigate whether the measurement of protein is dependent on the levels of fat present while using an infrared milk analyzer...
March 15, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28303125/antibiotic-and-desiccation-resistance-of-cronobacter-sakazakii-and-c-malonaticus-isolates-from-powdered-infant-formula-and-processing-environments
#6
Peng Fei, Yujun Jiang, Jing Feng, Stephen J Forsythe, Ran Li, Yanhong Zhou, Chaoxin Man
This study evaluated the antimicrobial and desiccation resistance of Cronobacter sakazakii and Cronobacter malonaticus isolates from powdered infant formula and processing environments. The antimicrobial susceptibility tests showed that the 70 Cronobacter strains, representing 19 sequence types, were susceptible to the most of the antibiotics except for amoxicillin-clavulanate, ampicillin, and cefazolin. Furthermore, the growth of six C. sakazakii and two C. malonaticus strains from different sequence types (STs) in hyperosmotic media was measured...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28294323/segmental-morphometrics-of-the-olive-baboon-papio-anubis-a-longitudinal-study-from-birth-to-adulthood
#7
François Druelle, Peter Aerts, Kristiaan D'Août, Valérie Moulin, Gilles Berillon
The linear dimensions and inertial characteristics of the body are important in locomotion and they change considerably during the ontogeny of animals, including humans. This longitudinal and ontogenetic study has produced the largest dataset to date of segmental morphometrics in a Catarrhini species, the olive baboon. The objectives of the study were to quantify the changes in body linear and inertial dimensions and to explore their (theoretical) mechanical significance for locomotion. We took full-body measurements of captive individuals at regular intervals...
March 14, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28293976/evolution-of-hybrid-interventions-for-congenital-heart-disease
#8
Hitesh Agrawal, Wail Alkashkari, Damien Kenny
Surgical and transcatheter interventions have seen a tremendous evolution in last three decades. Hybrid technology combines the achievements of both disciplines to bring substantial hemodynamic benefit to patients with congenital heart disease (CHD) in a minimally invasive manner. This collaboration between surgeons and interventionalists will continue to grow as the technology evolves to meet the demands of CHD patients, potentially avoiding cardiopulmonary bypass and vascular access complications as well as optimizing immediate technical outcomes with exit angiography...
March 15, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28292288/mobile-technology-for-community-health-in-ghana-what-happens-when-technical-functionality-threatens-the-effectiveness-of-digital-health-programs
#9
Amnesty E LeFevre, Diwakar Mohan, David Hutchful, Larissa Jennings, Garrett Mehl, Alain Labrique, Karen Romano, Anitha Moorthy
BACKGROUND: Despite the growing use of technology in the health sector, little evidence is available on the technological performance of mobile health programs nor on the willingness of target users to utilize these technologies as intended (behavioral performance). In this case study of the Mobile Technology for Health (MOTECH) program in Ghana, we assess the platform's effectiveness in delivering messages, along with user response across sites in five districts from 2011 to 2014. METHODS: MOTECH is comprised of "Client Data Application" (CDA) which allows providers to digitize and track service delivery information for women and infants and "Mobile Midwife" (MM) which sends automated educational voice messages to the mobile phones of pregnant and postpartum women...
March 14, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28285607/lipid-based-nutrient-supplements-and-linear-growth-in-children-under-2-years-a-review
#10
Tonderayi M Matsungo, Herculina S Kruger, Cornelius M Smuts, Mieke Faber
The prevalence of stunting remains high in low- and middle-income countries despite adoption of comprehensive nutrition interventions, particularly in low-income countries. In the present paper, we review current evidence on the acceptability and efficacy of small-quantity lipid-based nutrient supplements (SQ-LNS) on preventing stunting in children under 2 years, discuss the factors that affect their efficacy, highlight the implications of the current findings at pragmatic level and identify research priorities...
March 13, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/28281945/complication-after-extraction-of-natal-teeth-with-continued-growth-of-a-dental-papilla
#11
Sook Hee Kim, Young-Ah Cho, Ok Hyung Nam, Mi Sun Kim, Sung Chul Choi, Hyo-Seol Lee
The purposes of this case report were to describe a growing two-cm gingival mass that developed after natal teeth were extracted in a four-month-old female patient, present a review of the literature on the growth of a gingival mass after the extraction of natal teeth, and illustrate the clinical and histological features that differentiate this condition from other types of gingival masses in infants. Histological examination of the excised mass revealed that it contained tooth-like hard tissue (regular and irregular dentin) that intermingled with bone, dental pulp, and fibrous tissue...
November 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28262449/impact-of-the-zika-virus-for-anesthesiologists-a-review-of-current-literature-and-practices
#12
REVIEW
Benjamin J Heller, Menachem M Weiner, Joshua A Heller
Zika virus disease is of growing concern to all clinicians. There is a growing concern with regards to the neurologic sequela of the virus, particularly for infants born to women infected while pregnant. The continued spread of this virus throughout North and South America requires all anesthesiologists to maintain vigilance on this issue. This article addresses some of the key issues that pertain to anesthesiologists with regards to the Zika virus including the risks of perioperative management of patients with Zika virus...
December 2, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28253494/how-milk-and-its-proteins-affect-growth-bone-health-and-weight%C3%A2
#13
Michal Yackobovitch-Gavan, Moshe Phillip, Galia Gat-Yablonski
Milk has long been recognized to constitute a complete, well-balanced source of the nutrients and energy required to ensure the proper postnatal growth and development of infants. A growing body of evidence suggests the positive effects of dairy products and particularly of milk proteins on linear growth also in older children, both healthy or during recovery from malnutrition. This evidence led the way to the performance of extensive research aimed to delineate the components of milk and the mechanisms acting to make milk so effective...
March 2, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28244941/prenatal-breastfeeding-education-impact-on-infants-with-neonatal-abstinence-syndrome
#14
Kimberley Crook, Debra Brandon
BACKGROUND: Neonatal abstinence syndrome (NAS) is a growing problem in the United States, affecting 32,000 infants annually. Although breastfeeding would benefit infants with NAS, rates among these mothers are low. PURPOSE: The purpose of this quality improvement project was to increase breastfeeding rates and decrease hospital length of stay (LOS) for infants with NAS through prenatal breastfeeding initiatives. METHOD: A pre-/postquality improvement design was used to assess the relationship between breastfeeding initiatives on breastfeeding rates and LOS in infants with NAS...
February 27, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28241263/bridging-knowledge-gaps-to-understand-how-zika-virus-exposure-and-infection-affect-child-development
#15
Bill G Kapogiannis, Nahida Chakhtoura, Rohan Hazra, Catherine Y Spong
Importance: The Zika virus (ZIKV) epidemic has profoundly affected the lives of children and families across the Americas. As the number of children born with ZIKV-related complications continues to grow, the long-term developmental trajectory for these children and the effect on their families remains largely unknown. In September 2016, the Eunice Kennedy Shriver National Institute of Child Health and Human Development and partner National Institutes of Health institutes convened a workshop to develop a research agenda to improve the evaluation, monitoring, and management of neonates, infants, or children affected by ZIKV and its complications...
February 20, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28238854/use-of-a-probabilistic-pbpk-pd-model-to-calculate-data-derived-extrapolation-factors-for-chlorpyrifos
#16
Torka S Poet, Charles Timchalk, Michael J Bartels, Jordan N Smith, Robin McDougal, Daland R Juberg, Paul S Price
A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model combined with Monte Carlo analysis of inter-individual variation was used to assess the effects of the insecticide, chlorpyrifos and its active metabolite, chlorpyrifos oxon in humans. The PBPK/PD model has previously been validated and used to describe physiological changes in typical individuals as they grow from birth to adulthood. This model was updated to include physiological and metabolic changes that occur with pregnancy. The model was then used to assess the impact of inter-individual variability in physiology and biochemistry on predictions of internal dose metrics and quantitatively assess the impact of major sources of parameter uncertainty and biological diversity on the pharmacodynamics of red blood cell acetylcholinesterase inhibition...
February 24, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28238633/early-neonatal-death-a-challenge-worldwide
#17
REVIEW
Liisa Lehtonen, Ana Gimeno, Anna Parra-Llorca, Máximo Vento
Early neonatal death (ENND), defined as the death of a newborn between zero and seven days after birth, represents 73% of all postnatal deaths worldwide. Despite a 50% reduction in childhood mortality, reduction of ENND has significantly lagged behind other Millennium Developmental Goal achievements and is a growing contributor to overall mortality in children aged <5 years. The etiology of ENND is closely related to the level of a country's industrialization. Hence, prematurity and congenital anomalies are the leading causes in high-income countries...
February 23, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28229835/-neurodevelopmental-outcomes-of-very-preterm-or-very-low-birth-weigth-infants-comparison-of-monochorionic-and-dichorionic-twins-with-singletons
#18
Adelaide Taborda, Guiomar Oliveira
INTRODUCTION: Twins are associated with a delayed development and cerebral palsy. The purpose of this work was to compare the neurologic morbidity in very preterm or very low birth weight dichorionic and monochorionic twins with singletons. MATERIAL AND METHODS: We conducted a retrospective cohort study of livebirths lowest through 32 weeks of gestation or very low weight infants admitted to Neonatal Intensive Care Unit of a level III hospital, between 2006 and 2010...
November 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28196885/hemoglobin-phase-of-oxygenation-and-deoxygenation-in-early-brain-development-measured-using-fnirs
#19
Hama Watanabe, Yoshihiko Shitara, Yoshinori Aoki, Takanobu Inoue, Shinya Tsuchida, Naoto Takahashi, Gentaro Taga
A crucial issue in neonatal medicine is the impact of preterm birth on the developmental trajectory of the brain. Although a growing number of studies have shown alterations in the structure and function of the brain in preterm-born infants, we propose a method to detect subtle differences in neurovascular and metabolic functions in neonates and infants. Functional near-infrared spectroscopy (fNIRS) was used to obtain time-averaged phase differences between spontaneous low-frequency (less than 0.1 Hz) oscillatory changes in oxygenated hemoglobin (oxy-Hb) and those in deoxygenated hemoglobin (deoxy-Hb)...
February 28, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28196546/prevalence-and-factors-associated-with-depression-and-depression-related-healthcare-access-in-mothers-of-9-month-old-infants-in-the-republic-of-ireland
#20
S M Cruise, R Layte, M Stevenson, D O'Reilly
AIMS: Untreated maternal depression during the postpartum period can have a profound impact on the short- and long-term psychological and physical well-being of children. There is, therefore, an imperative for increased understanding of the determinants of depression and depression-related healthcare access during this period. METHODS: Respondents were 11 089 mothers of 9-month-old infants recruited to the Growing Up in Ireland study. Of this sample, 10 827 had complete data on all relevant variables...
February 15, 2017: Epidemiology and Psychiatric Sciences
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