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hepatitis B descriptive

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https://www.readbyqxmd.com/read/29644251/twenty-year-evolution-of-hepatitis-b-virus-and-human-immunodeficiency-virus-prevalence-and-incidence-in-voluntary-blood-donors-in-c%C3%A3-te-d-ivoire
#1
Benjamin Seri, Albert Minga, Delphine Gabillard, Bamori Dembele, Seidou Konate, Jérôme Le Carrou, Lambert Dohoun, Yao Abo, Sophie Karcher, Patrick Coffie, Thérèse N'Dri-Yoman, Alain Attia, Serge P Eholié, Christine Danel, Karine Lacombe, Xavier Anglaret, Anders Boyd
Background: Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) share common risk factors. The parallel description of their frequency over time may help capture their similarities and differences. Methods: Using data from the National Transfusion Center of Abidjan, we estimated the following over a 20-year period: (1) the prevalence of HIV and hepatitis B surface antigen (HBsAg) positivity at first contact; and (2) the incidence of HIV and HBsAg seroconversion in negative first-time blood donors...
April 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29596409/distinct-inflammatory-profile-underlies-pathological-increases-in-creatinine-levels-associated-with-plasmodium-vivax-malaria-clinical-severity
#2
Luís A B Cruz, Manoel Barral-Netto, Bruno B Andrade
BACKGROUND: Although Plasmodium vivax infection is a frequent cause of malaria worldwide, severe presentations have been more regularly described only in recent years. In this setting, despite clinical descriptions of multi-organ involvement, data associating it with kidney dysfunction are relatively scarce. Here, renal dysfunction is retrospectively analyzed in a large cohort of vivax malaria patients with an attempt to dissect its association with disease severity and mortality, and to determine the role of inflammation in its progression...
March 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29579055/proportion-and-predictors-of-transfusion-transmissible-infections-among-blood-donors-in-north-shewa-zone-central-north-ethiopia
#3
Tekalign Deressa, Wubet Birhan, Bamlaku Enawgaw, Molla Abebe, Habtamu Wondiferaw Baynes, Mekuria Desta, Betelihem Terefe, Mulugeta Melku
BACKGROUND: Transfusion-transmissible infections (TTIs) pose a significant challenge for the availability and safety of blood transfusion. The aim of this study was to investigate the prevalence and risk factors for TTIs among blood donors in North Shewa zone, central North Ethiopia. METHODS: A retrospective survey of blood donors' medical records was conducted from April 2014 to June 2017 to assess the presence of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and syphilis infections...
2018: PloS One
https://www.readbyqxmd.com/read/29561969/liver-transplantation-in-hepatitis-delta-south-america-experience
#4
Daniel Souza Lima, Abdon José Murad Júnior, Márcio Alencar Barreira, Guilherme Cardoso Fernandes, Gustavo Rego Coelho, José Huygens Parente Garcia
BACKGROUND: The Amazon region is one of the main endemic areas of hepatitis delta in the world and the only one related to the presence of genotype 3 of the delta virus. OBJECTIVE: To analyze the profile, mortality and survival of cirrhotic patients submitted to liver transplantation for chronic hepatitis delta virus and compare with those transplanted by hepatitis B virus monoinfection. METHODS: Retrospective, observational and descriptive study...
January 2018: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/29554828/management-of-hepatitis-b-reactivation-in-lymphoma-patients-on-rituximab-with-past-hepatitis-b-exposure-an-observational-study
#5
Denise Yeo, Ihtimam Hossain, Soon Thye Lim, Mohamad Farid, Miriam Tao, Richard Quek, Tiffany Tang, Alexandre Chan
Background Currently, a standardized approach to prevent and manage hepatitis B reactivation in lymphoma patients with past hepatitis exposure receiving rituximab in Singapore is lacking. This study is designed to report the current management approach and outcomes associated with hepatitis B reactivation. Objectives The primary objective was to report 6-, 12-, 24-month cumulative hepatitis B reactivation-related outcomes. Secondary objectives were to report monitoring frequencies of hepatitis B DNA and liver function tests performed in lymphoma patients with resolved hepatitis B receiving rituximab, and anti-viral prophylaxis use...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29534608/nucleoside-analogs-as-a-rich-source-of-antiviral-agents-active-against-arthropod-borne-flaviviruses
#6
Luděk Eyer, Radim Nencka, Erik de Clercq, Katherine Seley-Radtke, Daniel Růžek
Nucleoside analogs represent the largest class of small molecule-based antivirals, which currently form the backbone of chemotherapy of chronic infections caused by HIV, hepatitis B or C viruses, and herpes viruses. High antiviral potency and favorable pharmacokinetics parameters make some nucleoside analogs suitable also for the treatment of acute infections caused by other medically important RNA and DNA viruses. This review summarizes available information on antiviral research of nucleoside analogs against arthropod-borne members of the genus Flavivirus within the family Flaviviridae, being primarily focused on description of nucleoside inhibitors of flaviviral RNA-dependent RNA polymerase, methyltransferase, and helicase/NTPase...
January 2018: Antiviral Chemistry & Chemotherapy
https://www.readbyqxmd.com/read/29520729/pharmacokinetics-and-safety-of-velpatasvir-and-sofosbuvir-velpatasvir-in-subjects-with-hepatic-impairment
#7
Erik Mogalian, Diana M Brainard, Anu Osinusi, Lisa Moorehead, Bernard Murray, Kah Hiing John Ling, Robert Perry, Craig Curtis, Eric Lawitz, Kenneth Lasseter, Thomas Marbury, Anita Mathias
BACKGROUND: The pharmacokinetics and safety of velpatasvir, a potent pangenotypic hepatitis C virus NS5A inhibitor, were evaluated in two hepatic impairment studies: a phase I study in hepatitis C virus-uninfected subjects and a phase III study (ASTRAL-4) in hepatitis C virus-infected patients. METHODS: In the phase I study, subjects with moderate or severe hepatic impairment (Child-Pugh-Turcotte Class B or C), and demographically matched subjects with normal hepatic function received a single dose of velpatasvir 100 mg...
March 8, 2018: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/29512233/screening-recipients-of-increased-risk-donor-organs-a-multicenter-retrospective-study
#8
Michael G Ison, Meenakshi M Rana, Kyle D Brizendine, Sonia Chimienti, Jade Le, Rosette Kfoury, Parvin Mohazabnia, Nicole Theodoropoulos
BACKGROUND: Organ Procurement & Transplantation Network policy requires post-transplant screening of recipients of organs from donors at increased risk for transmission of HIV, hepatitis B virus and hepatitis C virus. Available data suggests that follow-up testing of recipients is not routinely conducted. METHODS: Data on increased risk donors and recipients of their organs from 2008-2012 was retrospectively collected from 6 transplant centers after IRB approval...
March 7, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29482629/primary-carcinosarcoma-of-the-liver-imaging-features-and-clinical-findings-in-six-cases-and-a-review-of-the-literature
#9
Jing Li, Pan Liang, Dandan Zhang, Jie Liu, Hongkai Zhang, Jinrong Qu, Jianbo Gao
BACKGROUND: Carcinosarcoma of the liver is a very rare tumor composed of a mixture of carcinomatous and sarcomatous elements. Less than 25 adequately documented cases have been reported, with inadequate description of imaging features. In order to improve the awareness of this rare tumor, this study aimed to analyze the clinicopathologic and imaging features of six cases of hepatic carcinosarcoma (HCS) confirmed by surgical pathologic evaluation. METHODS: We retrospectively studied the clinicopathologic and imaging features of six cases of HCS (matching the World Health Organization definition) and discussed the differential diagnosis on the basis of imaging findings...
February 27, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29459805/-hepatitis-b-and-c-prevalence-in-a-blood-bank-at-general-hospital-in-callao-peru
#10
Liliana Alvarez, Paul Jesús Tejada-Llacsa, Giannina Melgarejo-García, Gabriel Berto, Pedro Montes Teves, Eduardo Monge
OBJECTIVE: The aim of the present study was to determine the prevalence of sero positivity for HBsAg, Anti-HBcAg and AntiHVC in the blood bank of Hospital Daniel Carrion during the period 2010 - 2012. MATERIALS AND METHODS: Retrospective cross-sectional study. Potential donors who met the inclusion criteria were included. Sociodemographic factors, risk behaviors were gathered. A descriptive analysis was performed with STATA 14. RESULTS: 13,887 potential blood donors of the HNDAC between January 2010 and December 2012 were identified...
October 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29453472/prevalence-of-hepatitis-d-among-patients-with-hepatitis-b-viral-infection-attending-a-tertiary-care-centre-of-nepal
#11
Kiran Regmi, Jeetendra Kaji Shrestha, Sudhamshu Kc, Bikash Jaishi, Niyanta Karki, Dipendra Khadka, Sandip Khadka
INTRODUCTION: Worldwide there is variation in prevalence of Hepatitis D viral infection. Superinfection and co infection with hepatitis B viral infection is known to occur in 15-20 million people. METHODS: This was a descriptive cross-sectional hospital based study carried out in NAMS, Bir hospital, Kathmandu, Nepal from period of January 2017 to June 2017. Consecutive patients of chronic hepatitis B viral infection of HBsAg positive with more than two-time upper normal limit of ALT were enrolled and tested for HDV IgG...
October 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/29416843/perceptions-and-practice-of-health-care-workers-regarding-hepatitis-b-vaccination-bouak%C3%A3-c%C3%A3-te-d-ivoire-2016
#12
Damus Kouassi, Odile Angbo-Effi, Lepri Aka, M'Bégnan Coulibaly, Sory Soumahoro, Gnissan Yao, Nagho Soro
Barriers to immunization are seen in both the general population and the health care workforce. We conducted this study to determine the perception of health workers on vaccination and the immunization of their patients. This cross-sectional descriptive analytical study was carried out among the medical staff in Bouaké, from 10 January to 07 March 2016. The data collected from the interviews were analyzed using Epi info 2000 software and SPSS 17.0. The Chi-2 test and logistic regression were performed and the significance threshold of the tests was 5%...
December 31, 2017: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/29381647/recommendations-for-management-of-endemic-diseases-and-travel-medicine-in-solid-organ-transplant-recipients-and-donors-latin-america
#13
Wanessa Trindade Clemente, Lígia Camera Pierrotti, Edson Abdala, Michele I Morris, Luiz S Azevedo, Rogelio López-Vélez, Manuel Cuenca-Estrella, Julian Torre-Cisneros, Eskild Petersen, Luis Fernando A Camargo, Alissa Jade Wright, Nicholas J Beeching, Eduardo Garcia Vilela, Guilherme Santoro-Lopes, Oscar Len, Raquel S B Stucchi, Oriol Manuel, Luciana Costa Faria, Hakan Leblebicioglu, Shirish Huprikar, Israel Molina, Paulo Henrique Orlandi Mourão, Camille N Kotton, José María Aguado
The Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America clinical practice guideline is intended to guide clinicians caring for solid-organ transplant (SOT) donors, candidates and recipients regarding infectious diseases (ID) issues related to this geographical region, mostly located in the tropics. These recommendations are based on both systematic reviews of relevant literature and expert opinion from both transplant ID and travel medicine specialists...
February 2018: Transplantation
https://www.readbyqxmd.com/read/29241726/prevalence-and-risk-factors-of-hepatitis-d-virus-infection-in-patients-with-chronic-hepatitis-b-infection-attending-the-three-main-tertiary-hospitals-in-libya
#14
Abdel-Naser Elzouki, Saleh M Bashir, Omar Elahmer, Islam Elzouki, Fathi Alkhattali
BACKGROUND AND STUDY AIMS: Globally, More than 350 million individuals are chronically infected with hepatitis B virus (HBV), and >20 million of them are co-infected with hepatitis D virus (HDV). The aim of this study was to determine the pattern of HDV infection in patients with chronic hepatitis B in three main tertiary hospitals in Tripoli and Benghazi, Libya. PATIENTS AND METHODS: This cross sectional and descriptive study was conducted on 162 patients with chronic hepatitis B positive for more than six months) who were followed up at hepatitis clinics of the three main tertiary hospitals in Tripoli city (88 patients from Tripoli Medical Centre and Tripoli Central Hospital) and Benghazi city (74 patients from Aljomhoria Hospital) during the period from January 2010 to June 2012...
December 2017: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/29241647/safety-of-currently-licensed-hepatitis-b-surface-antigen-vaccines-in-the-united-states-vaccine-adverse-event-reporting-system-vaers-2005-2015
#15
Penina Haber, Pedro L Moro, Carmen Ng, Paige W Lewis, Beth Hibbs, Sarah F Schillie, Noele P Nelson, Rongxia Li, Brock Stewart, Maria V Cano
INTRODUCTION: Currently four recombinant hepatitis B (HepB) vaccines are in use in the United States. HepB vaccines are recommended for infants, children and adults. We assessed adverse events (AEs) following HepB vaccines reported to the Vaccine Adverse Event Reporting System (VAERS), a national spontaneous reporting system. METHODS: We searched VAERS for reports of AEs following single antigen HepB vaccine and HepB-containing vaccines (either given alone or with other vaccines), from January 2005 - December 2015...
January 25, 2018: Vaccine
https://www.readbyqxmd.com/read/29190726/socio-demographic-health-related-and-individual-correlates-of-diagnostic-self-testing-by-lay-people-results-from-a-representative-survey-in-germany
#16
Pinar Kuecuekbalaban, Silke Schmidt, Manfred Beutel, Kerstin Weidner, Martina de Zwaan, Elmar Braehler, Holger Muehlan
INTRODUCTION: A broad range of self-tests (testing for e.g. HIV, cancer, hepatitis B/C) have become available and can be conducted by lay consumers without the help of a health professional. The aims of this study were to (a) investigate the prevalence of self-testing, (b) identify the most frequently used self-tests, and (c) explore the associations between socio-demographic, health-related and individual factors with self-testing. METHODS: A face-to-face plus paper-pencil cross-sectional survey was conducted...
2017: PloS One
https://www.readbyqxmd.com/read/29181140/foetal-haemoglobin-and-disease-severity-in-nigerian-children-with-sickle-cell-anaemia
#17
Oluwagbemiga O Adeodu, Morenike A Akinlosotu, Samuel A Adegoke, Saheed B A Oseni
Background: Foetal haemoglobin (HbF) is a major modifying factor influencing sickle cell disease (SCD) severity. Despite this, HbF estimation is not routinely done in Nigeria. The relationship between HbF and SCD severity among affected children is also poorly studied. Methods: In this descriptive cross-sectional study, we determined the relationship between steady state HbF levels and disease severity of Nigerian children aged 1 - 15 years with homozygous SCD. For each child, the socio-demographic characteristics and SCD clinical severity were determined...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/29173103/social-norm-family-communication-and-hbv-screening-among-asian-americans
#18
RANDOMIZED CONTROLLED TRIAL
Hee-Soon Juon, Rajiv N Rimal, Ann Klassen, Sunmin Lee
Individuals' behaviors are influenced by those of others in their social environment (i.e., descriptive norms), as well as by how individuals perceive they should behave in that environment (e.g., injunctive norms). Although social norms are thought to play an important role in hepatitis B virus (HBV) screening, limited theoretical or empirical guidance exists on how the underlying process works. In addition, norms are social phenomena that are spread through family discussion about the importance of getting HBV screening...
December 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/29165125/nurses-willingness-to-care-for-patients-infected-with-hiv-or-hepatitis-b-c-in-vietnam
#19
Tomohiro Ishimaru, Koji Wada, Huong Thi Xuan Hoang, Anh Thi My Bui, Hung Dinh Nguyen, Hung Le, Derek R Smith
OBJECTIVES: This study examined the factors associated with nurses' willingness to care for patients infected with human immunodeficiency virus (HIV) or hepatitis B or C virus (HBV/HCV) in Vietnam. METHODS: A cross-section of 400 Vietnamese nurses from two hospitals were selected using stratified random sampling, to whom a self-administered questionnaire was administered which included demographic items, previous experience with patients infected with HIV or HBV/HCV, and their attitudes toward these patients...
March 16, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29158854/current-condition-of-chronic-hepatitis-b-virus-infection-in-cuban-adults
#20
Castellanos Fernández Marlen Ivón, Dorta Guridi Zaily, Da Silva Conde-Eduardo Leda Patricia, Galbán García Enrique, Arús Soler Enrique, Martinez Pérez Yadina
Background: The reduction of the incidence of hepatitis B virus (HBV) infection in Cuba can be attributed to the effectiveness of the national immunization program. However, the number of patients with chronic HBV observed in clinical practice is not negligible. Objective: A cross-sectional study was conducted to describe the main clinical characteristics of patients with chronic hepatitis B virus infection. Methods: A total of 146 patients who had at least a 6-month history of hepatitis B surface antigen positivity were recruited between 2013 and 2015...
2017: Current Therapeutic Research, Clinical and Experimental
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