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https://www.readbyqxmd.com/read/28549273/body-weight-supported-bedside-treadmill-training-facilitates-ambulation-in-icu-patients-an-interventional-proof-of-concept-study
#1
Juultje Sommers, Denise C Wieferink, Dave A Dongelmans, Frans Nollet, Raoul H H Engelbert, Marike van der Schaaf
PURPOSE: Early mobilisation is advocated to improve recovery of intensive care unit (ICU) survivors. However, severe weakness in combination with tubes, lines and machinery are practical barriers for the implementation of ambulation with critically ill patients. The aim of this study was to explore the feasibility of Body Weight-Supported Treadmill Training (BWSTT) in critically ill patients in the ICU. METHODS: A custom build bedside Body Weight-Supported Treadmill was used and evaluated in medical and surgical patients in the ICU...
May 13, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28545513/cross-sectional-assessment-of-infants-exposure-to-toxic-metals-through-breast-milk-in-a-prospective-cohort-study-of-mining-communities-in-ghana
#2
David Kwaku Bansa, Adolf Kofi Awua, Rose Boatin, Theodosia Adom, Edward Christian Brown-Appiah, Kennedy Kwame Amewosina, Akusika Diaba, Dominic Datoghe, Wilhelmina Okwabi
BACKGROUND: Although breastfeeding of infants is recommended globally, the fact that maternal toxic metal stores are mobilised into breast milk implies infants, whose mothers live and work in mining communities, are at risk of multiple exposure to mining related toxic metals, such as Lead (Pb), Mercury (Hg), Cadmium (Cd) and Arsenic (As), through breast milk intake, in addition to in utero exposure. METHOD: A total of 114 mother-baby pairs, recruited from two community hospitals servicing mining communities in two different regions in Ghana (57 each), were involved in this study...
May 25, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28544927/estuarine-sediment-resuspension-and-acidification-release-behaviour-of-contaminants-under-different-oxidation-levels-and-acid-sources
#3
M Camino Martín-Torre, Eva Cifrian, Gema Ruiz, Berta Galán, Javier R Viguri
Carbon dioxide (CO2) Capture and Storage (CCS) is a technology to reduce the emissions of this gas to the atmosphere by sequestering it in geological formations. In the case of offshore storage, unexpected CO2 leakages will acidify the marine environment. Reductions of the pH might be also caused by anthropogenic activities or natural events such as acid spills and dredging operations or storms and floods. Changes in the pH of the marine environment will trigger the mobilisation of elements trapped in contaminated shallow sediments with unclear redox boundary...
May 22, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28540806/laparoscopic-hyperthermic-isolated-limb-perfusion-a-new-minimally-invasive-approach-for-hilp
#4
N Solari, F Sucameli, M Gipponi, F De Cian, F Cafiero
BACKGROUND: Hyperthermic isolated limb perfusion (HILP) represents a limb-sparing treatment for unresectable soft tissue sarcoma (STS) of the extremities with substantial complete response rates. HILP often provides good functional limb preservation, hence a significant improvement also in terms of quality of life of the patient. Notwithstanding these clear advantages, the traditional technique is still hindered by relatively high post-operative morbidity. METHOD: We treated a 78-year-old female with unresectable angiosarcoma of the left leg using a new surgical approach: an entirely laparoscopic HILP...
April 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28537541/-earlier-weight-bearing-mobilisation-after-fracture-fixation
#5
P R G Brink, E J M M Verleisdonk, T J Blokhuis
Almost all the literature dictates a period of non-weight-bearing after surgical treatment of articular and peri-articular fractures of the pelvis and lower extremities. This is followed by partial weight-bearing which is based on the number of weeks after surgery. However, none of these recommendations are based on evidence. When taking muscle force and gravity into account, non-weight-bearing is actually impossible. In addition, lack of patient compliance, lack of muscle force in the elderly and four-fold energy expenditure make it almost impossible to ensure that patients will adhere to their surgeon's restrictions...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28537411/-treatment-of-pelvic-avulsion-fractures-in-children-and-adolescents
#6
A Stančák, J Kautzner, T Trč, V Havlas
INTRODUCTION: Paediatric avulsion fractures of the pelvis and hip joint are rare injuries most commonly associated with a rapid muscle contraction of the respected apophysis, which is the weakest component of the growing skeleton. The chosen therapy option can be either conservative or surgical. METHODS: We present a cohort of 69 patients treated for an apophyseal avulsion fracture of the anterior superior / inferior iliac spine, the lesser and greater trochanters iliac crest and the ischial tubercle...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28533235/the-tet39-determinant-and-the-msre-mphe-genes-in-acinetobacter-plasmids-are-each-part-of-discrete-modules-flanked-by-inversely-oriented-pdif-xerc-xerd-sites
#7
Grace A Blackwell, Ruth M Hall
The tet39 tetracycline resistance determinant and the macrolide resistance genes msrE and mphE were found in an 18.2 kb plasmid, pS30-1, recovered from a GC2 Acinetobacter baumannii isolate from Singapore, that conferred resistance to tetracycline and erythromycin. pS30-1 also contains mobA and mobC genes encoding MOBQ family proteins but attempts to mobilise pS30-1 utilising a co-resident conjugative repAci6 plasmid were unsuccessful. Eight pdif sites, consisting of inversely-oriented binding sites for the XerC and XerD recombinases separated by 6 bp, were detected in pS30-1...
May 22, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28532791/p518-a-small-flor-plasmid-from-a-south-american-isolate-of-actinobacillus-pleuropneumoniae
#8
Giarlã Cunha da Silva, Ciro César Rossi, Mateus Ferreira Santana, Paul R Langford, Janine T Bossé, Denise Mara Soares Bazzolli
A small (3.9kb) plasmid (p518), conferring resistance to florfenicol (MIC >8μg/mL) and chloramphenicol (MIC >8μg/mL) was isolated from an Actinobacillus pleuropneumoniae clinical isolate from Southeastern Brazil. To date, this is the smallest florfenicol resistance plasmid isolated from a member of the Pasteurellaceae. The complete nucleotide of this plasmid revealed a unique gene arrangement compared to previously reported florfenicol resistance plasmids found in other members of the Pasteurellaceae...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28531952/groundwater-quality-in-the-alluvial-aquifer-system-of-northwest-india-new-evidence-of-the-extent-of-anthropogenic-and-geogenic-contamination
#9
D J Lapworth, G Krishan, A M MacDonald, M S Rao
Groundwater depletion has been widely studied in northwest India, but water quality concerns are still poorly constrained. In this study, we explore the hydrochemistry of the top 160m of the aquifer system, through detailed field studies in the Bist-Doab region, considering both anthropogenic and geogenic controls. A detailed comparison is made between sites dominated by urban and agricultural landuse. Salinity, nitrate, chloride and lead concentrations are significantly higher in the shallow (0-50m) groundwater system due to surface anthropogenic contaminant loading from agricultural and urban sources...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28531946/the-role-of-mobilisation-and-delivery-processes-on-contrasting-dissolved-nitrogen-and-phosphorus-exports-in-groundwater-fed-catchments
#10
Rémi Dupas, Per-Erik Mellander, Chantal Gascuel-Odoux, Ophélie Fovet, Eoin B McAleer, Noeleen T McDonald, Mairead Shore, Phil Jordan
Diffuse transfer of nitrogen (N) and phosphorus (P) in agricultural catchments is controlled by the mobilisation of sources and their delivery to receiving waters. While plot scale experiments have focused on mobilisation processes, many catchment scale studies have hitherto concentrated on the controls of dominant flow pathways on nutrient delivery. To place mobilisation and delivery at a catchment scale, this study investigated their relative influence on contrasting nitrate-N and soluble P concentrations and N:P ratios in two shallow groundwater fed catchments with different land use (grassland and arable) on the Atlantic seaboard of Europe...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28529663/the-modified-dunn-procedure-for-slipped-capital-femoral-epiphysis-the-bernese-experience
#11
M Tannast, L M Jost, T D Lerch, F Schmaranzer, K Ziebarth, K A Siebenrock
PURPOSE: Based on previous investigations on the vascular blood supply to the femoral head, a technique for anatomical reduction after slipped capital femoral epiphysis was developed. This technique is a modification of the original technique by Dunn using a retinacular soft-tissue flap. This allows the visual control of the epiphyseal vascular blood supply. We report the experience at the inventor's institution with a critical discussion of the available literature. METHODS: Using a trochanteric osteotomy for surgical dislocation of the hip, a retinacular soft tissue flap is created containing the deep branch of the medial femoral circumflex artery, the external rotators and the capsule...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28528499/metal-transport-and-remobilisation-in-a-basin-affected-by-acid-mine-drainage-the-role-of-ochreous-amorphous-precipitates
#12
Sirio Consani, Cristina Carbone, Enrico Dinelli, Tonci Balić-Žunić, Laura Cutroneo, Marco Capello, Gabriella Salviulo, Gabriella Lucchetti
Metal-polluted mine waters represent a major threat to the quality of waters and sediments in a downstream basin. At the confluence between acidic mine waters and the unpolluted waters of the Gromolo Torrent (Liguria, North-West Italy), the massive formation of an ochreous amorphous precipitate takes place. This precipitate forms a soft blanket that covers the torrent bed and can be observed down to its mouth in the sea. The aim of this work is to evaluate the dispersion of metals in the Gromolo Torrent basin from the abandoned Cu-Fe sulphide mine of Libiola to the Ligurian Sea and to assess the metal remobilisation from the amorphous precipitates...
May 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28511653/processes-and-challenges-of-community-mobilisation-for-latrine-promotion-under-nirmal-bharat-abhiyan-in-rural-odisha-india
#13
Parimita Routray, Belen Torondel, Marion W Jenkins, Thomas Clasen, Wolf-Peter Schmidt
BACKGROUND: Despite efforts to eradicate it, open defecation remains widely practiced in India, especially in rural areas. Between 2013 and 2014, 50 villages in one district of Odisha, India, received a sanitation programme under the Nirmal Bharat Abhiyan (NBA - "Clean India Campaign"), the successor of India's Total Sanitation Campaign. This paper documents the strategies and processes of NBA community mobilisation for latrine promotion in these villages and assesses the strengths and limitations of the mobilisation activities...
May 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28510481/family-group-conferencing-its-added-value-in-mental-health-care
#14
Gert Schout, Ellen Meijer, Gideon de Jong
Worldwide, there is a growing emphasis on reducing coercion and involving social networks in the care of mental health clients. Nurses should encourage their clients to regain control over their lives, preferably with less coercion and with help from their social network. During four years, a Dutch evaluation study was deployed to determine the applicability of mobilising help from social networks of people with psychiatric problems. Specifically the potential of Family Group Conferencing was examined. In this discursive paper the question, 'what Family Group Conferencing adds to the existing methods that aim to reduce coercion in mental health care and promote inclusion' is addressed...
February 27, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28505579/effect-of-lupinus-albus-l-root-activities-on-as-and-cu-mobility-after-addition-of-iron-based-soil-amendments
#15
Teresa Fresno, Jesús M Peñalosa, Jakob Santner, Markus Puschenreiter, Eduardo Moreno-Jiménez
Arsenic and Cu mobility was investigated in the rhizosphere of Lupinus albus L. grown in an iron-amended contaminated soil. White lupin was grown in rhizobags in contaminated soil either left untreated or amended with iron sulphate plus lime (Fe + lime) or biochar (Fe + BC). Porewater was monitored in rhizosphere and bulk soil throughout the experiment and the extractable fraction of several elements and As and Cu plant uptake was analysed after 48 days. The distribution of As, Cu, P and Fe in the lupin rhizosphere was evaluated with chemical images obtained by laser ablation-ICP-MS analysis of diffusive gradients in thin films (DGT) gels...
May 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28501938/zoledronic-acid-renders-human-m1-and-m2-macrophages-susceptible-to-v%C3%AE-2-%C3%AE-%C3%AE-t-cell-cytotoxicity-in-a-perforin-dependent-manner
#16
Daniel W Fowler, John Copier, Angus G Dalgleish, Mark D Bodman-Smith
Vδ2(+) T cells are a subpopulation of γδ T cells in humans that are cytotoxic towards cells which accumulate isopentenyl pyrophosphate. The nitrogen-containing bisphosphonate, zoledronic acid (ZA), can induce tumour cell lines to accumulate isopentenyl pyrophosphate, thus rendering them more susceptible to Vδ2(+) T cell cytotoxicity. However, little is known about whether ZA renders other, non-malignant cell types susceptible. In this study we focussed on macrophages (Mϕs), as these cells have been shown to take up ZA...
May 13, 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28498049/the-paradox-of-recognition-hijra-third-gender-and-sexual-rights-in-bangladesh
#17
Adnan Hossain
Hijra, the iconic figure of South Asian gender and sexual difference, comprise a publicly institutionalised subculture of male-bodied feminine-identified people. Although they have existed as a culturally recognised third gender for a very long time, it is only recently that hijra have been legally recognised as a third gender in several South Asian countries. This paper focuses on the transformation of this long-running cultural category of third gender into a legal category of third gender in Bangladesh, showing that the process of legal recognition has necessitated a simultaneous mobilisation of a discourse of disability in the constitution of hijra as citizens worthy of rights...
May 12, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28497755/autologous-stem-cell-transplantation-in-treatment-refractory-crohn-s-disease-an-analysis-of-pooled-data-from-the-astic-trial
#18
James O Lindsay, Mathieu Allez, Miranda Clark, Myriam Labopin, Elenor Ricart, Gerhard Rogler, Montserrat Rovira, Jack Satsangi, Dominique Farge, Christopher J Hawkey
BACKGROUND: The randomised controlled ASTIC trial showed no benefit of mobilisation and autologous haematopoietic stem-cell transplantation (HSCT) compared with mobilisation followed by conventional therapy using a stringent primary endpoint (steroid-free clinical remission for 3 months with no endoscopic or radiological evidence of intestinal inflammation) in patients with treatment-refractory Crohn's disease. We now assess HSCT in patients enrolled in the ASTIC trial using endpoints that are traditional for clinical trials in Crohn's disease, and identify factors that predict benefit or harm...
June 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28495264/community-engagement-and-integrated-health-and-polio-immunisation-campaigns-in-conflict-affected-areas-of-pakistan-a-cluster-randomised-controlled-trial
#19
Muhammad Atif Habib, Sajid Soofi, Simon Cousens, Saeed Anwar, Najib Ul Haque, Imran Ahmed, Noshad Ali, Rehman Tahir, Zulfiqar A Bhutta
BACKGROUND: Pakistan faces huge challenges in eradicating polio due to widespread poliovirus transmission and security challenges. Innovative interventions are urgently needed to strengthen community buy-in, to increase the coverage of oral polio vaccine (OPV) and other routine immunisations, and to enhance immunity through the introduction of inactivated polio vaccine (IPV) in combination with OPV. We aimed to evaluate the acceptability and effect on immunisation coverage of an integrated strategy for community engagement and maternal and child health immunisation campaigns in insecure and conflict-affected polio-endemic districts of Pakistan...
June 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28494356/appraising-the-role-of-environment-friendly-chelants-in-alleviating-lead-by-coronopus-didymus-from-pb-contaminated-soils
#20
Gagan Preet Singh Sidhu, Harminder Pal Singh, Daizy R Batish, Ravinder Kumar Kohli
In a screenhouse experiment, we investigated the role of two environment friendly chelants, Ammonium molybdate and EDDS for Pb mobilisation and its extraction by Coronopus didymus under completely randomized controlled conditions. Seedlings of C. didymus were grown in pots having Pb-contaminated soil (1200 and 2200 mg kg(-1)) for 6 weeks. Plants were harvested, 1 week after the addition of A. molybdate and EDDS. Results revealed that A. molybdate and EDDS enhanced the uptake and accumulation of Pb in roots and shoots of C...
May 4, 2017: Chemosphere
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